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PMC:1440874 / 41460-44131 JSONTXT

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Id Subject Object Predicate Lexical cue
T8999 0-4 NN denotes Atrx
T9000 5-10 VBZ denotes joins
T9001 11-13 DT denotes an
T9002 24-28 NN denotes list
T9003 14-23 VBG denotes expanding
T9004 29-31 IN denotes of
T9005 32-37 NN denotes mouse
T9006 38-43 NNS denotes genes
T9007 44-47 IN denotes for
T9008 74-81 VBZ denotes results
T9009 48-53 WDT denotes which
T9010 54-62 VBN denotes targeted
T9011 63-73 NN denotes disruption
T9012 82-84 IN denotes in
T9013 85-102 JJ denotes peri-implantation
T9014 103-112 NN denotes lethality
T9015 113-115 IN denotes as
T9016 116-117 DT denotes a
T9017 118-124 NN denotes result
T9018 125-127 IN denotes of
T9019 128-139 NN denotes trophoblast
T9020 153-166 NNS denotes abnormalities
T9021 140-142 CC denotes or
T9022 143-152 JJ denotes placental
T9023 167-168 -LRB- denotes (
T9024 168-176 VBN denotes reviewed
T9025 177-179 IN denotes in
T9026 180-181 -LRB- denotes [
T9027 181-183 CD denotes 25
T9028 183-184 -RRB- denotes ]
T9029 184-185 -RRB- denotes )
T9030 185-186 . denotes .
T9031 186-296 sentence denotes Comparison with other phenotypes might provide some insight into the role of Atrx in trophoblast development.
T9032 187-197 NN denotes Comparison
T9033 226-233 VB denotes provide
T9034 198-202 IN denotes with
T9035 203-208 JJ denotes other
T9036 209-219 NNS denotes phenotypes
T9037 220-225 MD denotes might
T9038 234-238 DT denotes some
T9039 239-246 NN denotes insight
T9040 247-251 IN denotes into
T9041 252-255 DT denotes the
T9042 256-260 NN denotes role
T9043 261-263 IN denotes of
T9044 264-268 NN denotes Atrx
T9045 269-271 IN denotes in
T9046 272-283 NN denotes trophoblast
T9047 284-295 NN denotes development
T9048 295-296 . denotes .
T9049 296-512 sentence denotes Atrx-mutant embryos progress further than embryos nullizygous for factors involved in the initial specification of trophoblast stem cells (such as Cdx2) or in stem cell maintenance and proliferation (such as Eomes).
T9050 297-301 NN denotes Atrx
T9051 302-308 NN denotes mutant
T9052 301-302 HYPH denotes -
T9053 309-316 NNS denotes embryos
T9054 317-325 VBP denotes progress
T9055 326-333 RB denotes further
T9056 334-338 IN denotes than
T9057 339-346 NNS denotes embryos
T9058 347-358 JJ denotes nullizygous
T9059 359-362 IN denotes for
T9060 363-370 NNS denotes factors
T9061 371-379 VBN denotes involved
T9062 380-382 IN denotes in
T9063 383-386 DT denotes the
T9064 395-408 NN denotes specification
T9065 387-394 JJ denotes initial
T9066 409-411 IN denotes of
T9067 412-423 NN denotes trophoblast
T9068 429-434 NNS denotes cells
T9069 424-428 NN denotes stem
T9070 435-436 -LRB- denotes (
T9071 441-443 IN denotes as
T9072 436-440 JJ denotes such
T9073 444-448 NN denotes Cdx2
T9074 448-449 -RRB- denotes )
T9075 450-452 CC denotes or
T9076 453-455 IN denotes in
T9077 456-460 NN denotes stem
T9078 466-477 NN denotes maintenance
T9079 461-465 NN denotes cell
T9080 478-481 CC denotes and
T9081 482-495 NN denotes proliferation
T9082 496-497 -LRB- denotes (
T9083 502-504 IN denotes as
T9084 497-501 JJ denotes such
T9085 505-510 NN denotes Eomes
T9086 510-511 -RRB- denotes )
T9087 511-512 . denotes .
T9088 512-748 sentence denotes Cdx2-mutant embryos fail to implant and die between 3.5 and 5.5 dpc [26], while Eomes-mutant blastocysts implant into the uterus, but arrest soon after implantation without forming organised embryonic or extraembryonic structures [27].
T9089 513-517 NN denotes Cdx2
T9090 518-524 NN denotes mutant
T9091 517-518 HYPH denotes -
T9092 525-532 NNS denotes embryos
T9093 533-537 VBP denotes fail
T9094 538-540 TO denotes to
T9095 541-548 VB denotes implant
T9096 549-552 CC denotes and
T9097 553-556 VBP denotes die
T9098 557-564 IN denotes between
T9099 565-568 CD denotes 3.5
T9100 577-580 NN denotes dpc
T9101 569-572 CC denotes and
T9102 573-576 CD denotes 5.5
T9103 581-582 -LRB- denotes [
T9104 582-584 CD denotes 26
T9105 584-585 -RRB- denotes ]
T9106 585-587 , denotes ,
T9107 587-592 IN denotes while
T9108 618-625 VBP denotes implant
T9109 593-598 NN denotes Eomes
T9110 599-605 NN denotes mutant
T9111 598-599 HYPH denotes -
T9112 606-617 NNS denotes blastocysts
T9113 626-630 IN denotes into
T9114 631-634 DT denotes the
T9115 635-641 NN denotes uterus
T9116 641-643 , denotes ,
T9117 643-646 CC denotes but
T9118 647-653 VBP denotes arrest
T9119 654-658 RB denotes soon
T9120 659-664 IN denotes after
T9121 665-677 NN denotes implantation
T9122 678-685 IN denotes without
T9123 686-693 VBG denotes forming
T9124 694-703 VBN denotes organised
T9125 732-742 NNS denotes structures
T9126 704-713 JJ denotes embryonic
T9127 714-716 CC denotes or
T9128 717-731 JJ denotes extraembryonic
T9129 743-744 -LRB- denotes [
T9130 744-746 CD denotes 27
T9131 746-747 -RRB- denotes ]
T9132 747-748 . denotes .
T9133 748-859 sentence denotes In contrast, Atrx-mutant embryos implant successfully and establish organised embryonic structures by 7.5 dpc.
T9134 749-751 IN denotes In
T9135 782-789 VBP denotes implant
T9136 752-760 NN denotes contrast
T9137 760-762 , denotes ,
T9138 762-766 NN denotes Atrx
T9139 767-773 NN denotes mutant
T9140 766-767 HYPH denotes -
T9141 774-781 NNS denotes embryos
T9142 790-802 RB denotes successfully
T9143 803-806 CC denotes and
T9144 807-816 VBP denotes establish
T9145 817-826 VBN denotes organised
T9146 837-847 NNS denotes structures
T9147 827-836 JJ denotes embryonic
T9148 848-850 IN denotes by
T9149 851-854 CD denotes 7.5
T9150 855-858 NN denotes dpc
T9151 858-859 . denotes .
T9152 859-996 sentence denotes The Atrx-mutant phenotype closely resembles that observed in mice nullizygous for the basic helix-loop-helix transcription factor Hand1.
T9153 860-863 DT denotes The
T9154 876-885 NN denotes phenotype
T9155 864-868 NN denotes Atrx
T9156 869-875 NN denotes mutant
T9157 868-869 HYPH denotes -
T9158 894-903 VBZ denotes resembles
T9159 886-893 RB denotes closely
T9160 904-908 DT denotes that
T9161 909-917 VBN denotes observed
T9162 918-920 IN denotes in
T9163 921-925 NNS denotes mice
T9164 926-937 JJ denotes nullizygous
T9165 938-941 IN denotes for
T9166 942-945 DT denotes the
T9167 983-989 NN denotes factor
T9168 946-951 JJ denotes basic
T9169 952-957 NN denotes helix
T9170 963-968 NN denotes helix
T9171 957-958 HYPH denotes -
T9172 958-962 NN denotes loop
T9173 962-963 HYPH denotes -
T9174 969-982 NN denotes transcription
T9175 990-995 NN denotes Hand1
T9176 995-996 . denotes .
T9177 996-1222 sentence denotes Hand1-mutant conceptuses arrest at around 7.5 dpc and display a normal embryonic compartment, but, like Atrx-mutant embryos, ablation of Hand1 causes a reduction in the size of the ectoplacental cone and density of TGCs [28].
T9178 997-1002 NN denotes Hand1
T9179 1003-1009 NN denotes mutant
T9180 1002-1003 HYPH denotes -
T9181 1010-1021 NNS denotes conceptuses
T9182 1022-1028 VBP denotes arrest
T9183 1029-1031 IN denotes at
T9184 1032-1038 IN denotes around
T9185 1039-1042 CD denotes 7.5
T9186 1043-1046 NN denotes dpc
T9187 1047-1050 CC denotes and
T9188 1051-1058 VBP denotes display
T9189 1059-1060 DT denotes a
T9190 1078-1089 NN denotes compartment
T9191 1061-1067 JJ denotes normal
T9192 1068-1077 JJ denotes embryonic
T9193 1089-1091 , denotes ,
T9194 1091-1094 CC denotes but
T9195 1094-1096 , denotes ,
T9196 1096-1100 IN denotes like
T9197 1140-1146 VBZ denotes causes
T9198 1101-1105 NN denotes Atrx
T9199 1106-1112 NN denotes mutant
T9200 1105-1106 HYPH denotes -
T9201 1113-1120 NNS denotes embryos
T9202 1120-1122 , denotes ,
T9203 1122-1130 NN denotes ablation
T9204 1131-1133 IN denotes of
T9205 1134-1139 NN denotes Hand1
T9206 1147-1148 DT denotes a
T9207 1149-1158 NN denotes reduction
T9208 1159-1161 IN denotes in
T9209 1162-1165 DT denotes the
T9210 1166-1170 NN denotes size
T9211 1171-1173 IN denotes of
T9212 1174-1177 DT denotes the
T9213 1192-1196 NN denotes cone
T9214 1178-1191 JJ denotes ectoplacental
T9215 1197-1200 CC denotes and
T9216 1201-1208 NN denotes density
T9217 1209-1211 IN denotes of
T9218 1212-1216 NNS denotes TGCs
T9219 1217-1218 -LRB- denotes [
T9220 1218-1220 CD denotes 28
T9221 1220-1221 -RRB- denotes ]
T9222 1221-1222 . denotes .
T9223 1222-1325 sentence denotes As with Atrx mutants, only arrested or resorbed Hand1-mutant conceptuses were recovered after 8.5 dpc.
T9224 1223-1225 IN denotes As
T9225 1301-1310 VBN denotes recovered
T9226 1226-1230 IN denotes with
T9227 1231-1235 NN denotes Atrx
T9228 1236-1243 NNS denotes mutants
T9229 1243-1245 , denotes ,
T9230 1245-1249 RB denotes only
T9231 1284-1295 NNS denotes conceptuses
T9232 1250-1258 VBN denotes arrested
T9233 1259-1261 CC denotes or
T9234 1262-1270 VBN denotes resorbed
T9235 1271-1276 NN denotes Hand1
T9236 1277-1283 NN denotes mutant
T9237 1276-1277 HYPH denotes -
T9238 1296-1300 VBD denotes were
T9239 1311-1316 IN denotes after
T9240 1317-1320 CD denotes 8.5
T9241 1321-1324 NN denotes dpc
T9242 1324-1325 . denotes .
T9243 1325-1483 sentence denotes Also like Atrx, disruption of Hand1 specifically affects secondary giant cell formation, and primary trophoblast outgrowths from blastocysts appeared normal.
T9244 1326-1330 RB denotes Also
T9245 1375-1382 VBZ denotes affects
T9246 1331-1335 IN denotes like
T9247 1336-1340 NN denotes Atrx
T9248 1340-1342 , denotes ,
T9249 1342-1352 NN denotes disruption
T9250 1353-1355 IN denotes of
T9251 1356-1361 NN denotes Hand1
T9252 1362-1374 RB denotes specifically
T9253 1383-1392 JJ denotes secondary
T9254 1399-1403 NN denotes cell
T9255 1393-1398 JJ denotes giant
T9256 1404-1413 NN denotes formation
T9257 1413-1415 , denotes ,
T9258 1415-1418 CC denotes and
T9259 1419-1426 JJ denotes primary
T9260 1439-1449 NNS denotes outgrowths
T9261 1427-1438 NN denotes trophoblast
T9262 1467-1475 VBD denotes appeared
T9263 1450-1454 IN denotes from
T9264 1455-1466 NNS denotes blastocysts
T9265 1476-1482 JJ denotes normal
T9266 1482-1483 . denotes .
T9267 1483-1649 sentence denotes Hand1 is required for terminal differentiation of secondary TGCs, and in its absence trophoblast cells arrest at a precursor stage in the ectoplacental cone [17,28].
T9268 1484-1489 NN denotes Hand1
T9269 1493-1501 VBN denotes required
T9270 1490-1492 VBZ denotes is
T9271 1502-1505 IN denotes for
T9272 1506-1514 JJ denotes terminal
T9273 1515-1530 NN denotes differentiation
T9274 1531-1533 IN denotes of
T9275 1534-1543 JJ denotes secondary
T9276 1544-1548 NNS denotes TGCs
T9277 1548-1550 , denotes ,
T9278 1550-1553 CC denotes and
T9279 1554-1556 IN denotes in
T9280 1587-1593 VBP denotes arrest
T9281 1557-1560 PRP$ denotes its
T9282 1561-1568 NN denotes absence
T9283 1569-1580 NN denotes trophoblast
T9284 1581-1586 NNS denotes cells
T9285 1594-1596 IN denotes at
T9286 1597-1598 DT denotes a
T9287 1609-1614 NN denotes stage
T9288 1599-1608 NN denotes precursor
T9289 1615-1617 IN denotes in
T9290 1618-1621 DT denotes the
T9291 1636-1640 NN denotes cone
T9292 1622-1635 JJ denotes ectoplacental
T9293 1641-1642 -LRB- denotes [
T9294 1645-1647 CD denotes 28
T9295 1642-1644 CD denotes 17
T9296 1644-1645 , denotes ,
T9297 1647-1648 -RRB- denotes ]
T9298 1648-1649 . denotes .
T9299 1649-2020 sentence denotes Given the similarity of the Atrx- and Hand1-mutant phenotypes and the likelihood that Atrx acts as a transcriptional regulator by modifying chromatin structure, it will be of interest to determine whether Atrx is itself a regulator of Hand1 expression, or alternatively whether it acts as a co-regulator of one or more of the downstream transcriptional targets of Hand1.
T9300 1650-1655 VBN denotes Given
T9301 1819-1821 VB denotes be
T9302 1656-1659 DT denotes the
T9303 1660-1670 NN denotes similarity
T9304 1671-1673 IN denotes of
T9305 1674-1677 DT denotes the
T9306 1701-1711 NNS denotes phenotypes
T9307 1678-1682 NN denotes Atrx
T9308 1694-1700 NN denotes mutant
T9309 1682-1683 HYPH denotes -
T9310 1684-1687 CC denotes and
T9311 1688-1693 NN denotes Hand1
T9312 1693-1694 HYPH denotes -
T9313 1712-1715 CC denotes and
T9314 1716-1719 DT denotes the
T9315 1720-1730 NN denotes likelihood
T9316 1731-1735 IN denotes that
T9317 1741-1745 VBZ denotes acts
T9318 1736-1740 NN denotes Atrx
T9319 1746-1748 IN denotes as
T9320 1749-1750 DT denotes a
T9321 1767-1776 NN denotes regulator
T9322 1751-1766 JJ denotes transcriptional
T9323 1777-1779 IN denotes by
T9324 1780-1789 VBG denotes modifying
T9325 1790-1799 NN denotes chromatin
T9326 1800-1809 NN denotes structure
T9327 1809-1811 , denotes ,
T9328 1811-1813 PRP denotes it
T9329 1814-1818 MD denotes will
T9330 1822-1824 IN denotes of
T9331 1825-1833 NN denotes interest
T9332 1834-1836 TO denotes to
T9333 1837-1846 VB denotes determine
T9334 1847-1854 IN denotes whether
T9335 1860-1862 VBZ denotes is
T9336 1855-1859 NN denotes Atrx
T9337 1863-1869 PRP denotes itself
T9338 1870-1871 DT denotes a
T9339 1872-1881 NN denotes regulator
T9340 1882-1884 IN denotes of
T9341 1885-1890 NN denotes Hand1
T9342 1891-1901 NN denotes expression
T9343 1901-1903 , denotes ,
T9344 1903-1905 CC denotes or
T9345 1906-1919 RB denotes alternatively
T9346 1931-1935 VBZ denotes acts
T9347 1920-1927 IN denotes whether
T9348 1928-1930 PRP denotes it
T9349 1936-1938 IN denotes as
T9350 1939-1940 DT denotes a
T9351 1941-1953 NN denotes co-regulator
T9352 1954-1956 IN denotes of
T9353 1957-1960 CD denotes one
T9354 1961-1963 CC denotes or
T9355 1964-1968 JJR denotes more
T9356 1969-1971 IN denotes of
T9357 1972-1975 DT denotes the
T9358 2003-2010 NNS denotes targets
T9359 1976-1986 JJ denotes downstream
T9360 1987-2002 JJ denotes transcriptional
T9361 2011-2013 IN denotes of
T9362 2014-2019 NN denotes Hand1
T9363 2019-2020 . denotes .
T9364 2020-2153 sentence denotes It is noteworthy that, in the brain-specific Atrx knockout mice, the defect was observed in terminally differentiating neurons [20].
T9365 2021-2023 PRP denotes It
T9366 2024-2026 VBZ denotes is
T9367 2027-2037 JJ denotes noteworthy
T9368 2038-2042 IN denotes that
T9369 2101-2109 VBN denotes observed
T9370 2042-2044 , denotes ,
T9371 2044-2046 IN denotes in
T9372 2047-2050 DT denotes the
T9373 2080-2084 NNS denotes mice
T9374 2051-2056 NN denotes brain
T9375 2057-2065 JJ denotes specific
T9376 2056-2057 HYPH denotes -
T9377 2066-2070 NN denotes Atrx
T9378 2071-2079 NN denotes knockout
T9379 2084-2086 , denotes ,
T9380 2086-2089 DT denotes the
T9381 2090-2096 NN denotes defect
T9382 2097-2100 VBD denotes was
T9383 2110-2112 IN denotes in
T9384 2113-2123 RB denotes terminally
T9385 2124-2139 VBG denotes differentiating
T9386 2140-2147 NNS denotes neurons
T9387 2148-2149 -LRB- denotes [
T9388 2149-2151 CD denotes 20
T9389 2151-2152 -RRB- denotes ]
T9390 2152-2153 . denotes .
T9391 2153-2462 sentence denotes The secondary TGCs affected in the universal Atrx knockout reported here represent one of the first terminally differentiated tissues in the developing mouse, and this may point to the requirement for Atrx in the high-level expression of some tissue-specific genes during the final stages of differentiation.
T9392 2154-2157 DT denotes The
T9393 2168-2172 NNS denotes TGCs
T9394 2158-2167 JJ denotes secondary
T9395 2227-2236 VBP denotes represent
T9396 2173-2181 VBN denotes affected
T9397 2182-2184 IN denotes in
T9398 2185-2188 DT denotes the
T9399 2204-2212 NN denotes knockout
T9400 2189-2198 JJ denotes universal
T9401 2199-2203 NN denotes Atrx
T9402 2213-2221 VBN denotes reported
T9403 2222-2226 RB denotes here
T9404 2237-2240 CD denotes one
T9405 2241-2243 IN denotes of
T9406 2244-2247 DT denotes the
T9407 2280-2287 NNS denotes tissues
T9408 2248-2253 JJ denotes first
T9409 2254-2264 RB denotes terminally
T9410 2265-2279 VBN denotes differentiated
T9411 2288-2290 IN denotes in
T9412 2291-2294 DT denotes the
T9413 2306-2311 NN denotes mouse
T9414 2295-2305 VBG denotes developing
T9415 2311-2313 , denotes ,
T9416 2313-2316 CC denotes and
T9417 2317-2321 DT denotes this
T9418 2326-2331 VB denotes point
T9419 2322-2325 MD denotes may
T9420 2332-2334 IN denotes to
T9421 2335-2338 DT denotes the
T9422 2339-2350 NN denotes requirement
T9423 2351-2354 IN denotes for
T9424 2355-2359 NN denotes Atrx
T9425 2360-2362 IN denotes in
T9426 2363-2366 DT denotes the
T9427 2378-2388 NN denotes expression
T9428 2367-2371 JJ denotes high
T9429 2372-2377 NN denotes level
T9430 2371-2372 HYPH denotes -
T9431 2389-2391 IN denotes of
T9432 2392-2396 DT denotes some
T9433 2413-2418 NNS denotes genes
T9434 2397-2403 NN denotes tissue
T9435 2404-2412 JJ denotes specific
T9436 2403-2404 HYPH denotes -
T9437 2419-2425 IN denotes during
T9438 2426-2429 DT denotes the
T9439 2436-2442 NNS denotes stages
T9440 2430-2435 JJ denotes final
T9441 2443-2445 IN denotes of
T9442 2446-2461 NN denotes differentiation
T9443 2461-2462 . denotes .
T9444 2462-2670 sentence denotes Interestingly, the α-globin genes, the only confirmed transcriptional targets of regulation by human ATRX, are also highly expressed specifically during terminal differentiation within the erythroid lineage.
T9445 2463-2476 RB denotes Interestingly
T9446 2586-2595 VBN denotes expressed
T9447 2476-2478 , denotes ,
T9448 2478-2481 DT denotes the
T9449 2491-2496 NNS denotes genes
T9450 2482-2483 NN denotes α
T9451 2484-2490 NN denotes globin
T9452 2483-2484 HYPH denotes -
T9453 2496-2498 , denotes ,
T9454 2498-2501 DT denotes the
T9455 2533-2540 NNS denotes targets
T9456 2502-2506 RB denotes only
T9457 2507-2516 VBN denotes confirmed
T9458 2517-2532 JJ denotes transcriptional
T9459 2541-2543 IN denotes of
T9460 2544-2554 NN denotes regulation
T9461 2555-2557 IN denotes by
T9462 2558-2563 JJ denotes human
T9463 2564-2568 NN denotes ATRX
T9464 2568-2570 , denotes ,
T9465 2570-2573 VBP denotes are
T9466 2574-2578 RB denotes also
T9467 2579-2585 RB denotes highly
T9468 2596-2608 RB denotes specifically
T9469 2609-2615 IN denotes during
T9470 2616-2624 JJ denotes terminal
T9471 2625-2640 NN denotes differentiation
T9472 2641-2647 IN denotes within
T9473 2648-2651 DT denotes the
T9474 2662-2669 NN denotes lineage
T9475 2652-2661 JJ denotes erythroid
T9476 2669-2670 . denotes .
R5462 T8999 T9000 nsubj Atrx,joins
R5463 T9001 T9002 det an,list
R5464 T9002 T9000 dobj list,joins
R5465 T9003 T9002 amod expanding,list
R5466 T9004 T9002 prep of,list
R5467 T9005 T9006 compound mouse,genes
R5468 T9006 T9004 pobj genes,of
R5469 T9007 T9008 prep for,results
R5470 T9008 T9002 relcl results,list
R5471 T9009 T9007 pobj which,for
R5472 T9010 T9011 amod targeted,disruption
R5473 T9011 T9008 nsubj disruption,results
R5474 T9012 T9008 prep in,results
R5475 T9013 T9014 amod peri-implantation,lethality
R5476 T9014 T9012 pobj lethality,in
R5477 T9015 T9008 prep as,results
R5478 T9016 T9017 det a,result
R5479 T9017 T9015 pobj result,as
R5480 T9018 T9017 prep of,result
R5481 T9019 T9020 nmod trophoblast,abnormalities
R5482 T9020 T9018 pobj abnormalities,of
R5483 T9021 T9019 cc or,trophoblast
R5484 T9022 T9019 conj placental,trophoblast
R5485 T9023 T9024 punct (,reviewed
R5486 T9024 T9000 parataxis reviewed,joins
R5487 T9025 T9024 prep in,reviewed
R5488 T9026 T9025 punct [,in
R5489 T9027 T9025 pobj 25,in
R5490 T9028 T9024 punct ],reviewed
R5491 T9029 T9024 punct ),reviewed
R5492 T9030 T9000 punct .,joins
R5493 T9032 T9033 nsubj Comparison,provide
R5494 T9034 T9032 prep with,Comparison
R5495 T9035 T9036 amod other,phenotypes
R5496 T9036 T9034 pobj phenotypes,with
R5497 T9037 T9033 aux might,provide
R5498 T9038 T9039 det some,insight
R5499 T9039 T9033 dobj insight,provide
R5500 T9040 T9033 prep into,provide
R5501 T9041 T9042 det the,role
R5502 T9042 T9040 pobj role,into
R5503 T9043 T9042 prep of,role
R5504 T9044 T9043 pobj Atrx,of
R5505 T9045 T9042 prep in,role
R5506 T9046 T9047 compound trophoblast,development
R5507 T9047 T9045 pobj development,in
R5508 T9048 T9033 punct .,provide
R5509 T9050 T9051 compound Atrx,mutant
R5510 T9051 T9053 compound mutant,embryos
R5511 T9052 T9051 punct -,mutant
R5512 T9053 T9054 nsubj embryos,progress
R5513 T9055 T9054 advmod further,progress
R5514 T9056 T9055 prep than,further
R5515 T9057 T9056 pobj embryos,than
R5516 T9058 T9057 amod nullizygous,embryos
R5517 T9059 T9058 prep for,nullizygous
R5518 T9060 T9059 pobj factors,for
R5519 T9061 T9060 acl involved,factors
R5520 T9062 T9061 prep in,involved
R5521 T9063 T9064 det the,specification
R5522 T9064 T9062 pobj specification,in
R5523 T9065 T9064 amod initial,specification
R5524 T9066 T9064 prep of,specification
R5525 T9067 T9068 compound trophoblast,cells
R5526 T9068 T9066 pobj cells,of
R5527 T9069 T9068 compound stem,cells
R5528 T9070 T9071 punct (,as
R5529 T9071 T9064 parataxis as,specification
R5530 T9072 T9071 amod such,as
R5531 T9073 T9071 pobj Cdx2,as
R5532 T9074 T9071 punct ),as
R5533 T9075 T9062 cc or,in
R5534 T9076 T9062 conj in,in
R5535 T9077 T9078 compound stem,maintenance
R5536 T9078 T9076 pobj maintenance,in
R5537 T9079 T9078 compound cell,maintenance
R5538 T9080 T9078 cc and,maintenance
R5539 T9081 T9078 conj proliferation,maintenance
R5540 T9082 T9083 punct (,as
R5541 T9083 T9078 parataxis as,maintenance
R5542 T9084 T9083 amod such,as
R5543 T9085 T9083 pobj Eomes,as
R5544 T9086 T9083 punct ),as
R5545 T9087 T9054 punct .,progress
R5546 T9089 T9090 compound Cdx2,mutant
R5547 T9090 T9092 compound mutant,embryos
R5548 T9091 T9090 punct -,mutant
R5549 T9092 T9093 nsubj embryos,fail
R5550 T9094 T9095 aux to,implant
R5551 T9095 T9093 xcomp implant,fail
R5552 T9096 T9093 cc and,fail
R5553 T9097 T9093 conj die,fail
R5554 T9098 T9099 quantmod between,3.5
R5555 T9099 T9100 nummod 3.5,dpc
R5556 T9100 T9097 dobj dpc,die
R5557 T9101 T9099 cc and,3.5
R5558 T9102 T9099 conj 5.5,3.5
R5559 T9103 T9104 punct [,26
R5560 T9104 T9093 parataxis 26,fail
R5561 T9105 T9104 punct ],26
R5562 T9106 T9093 punct ", ",fail
R5563 T9107 T9108 mark while,implant
R5564 T9108 T9093 advcl implant,fail
R5565 T9109 T9110 compound Eomes,mutant
R5566 T9110 T9112 compound mutant,blastocysts
R5567 T9111 T9110 punct -,mutant
R5568 T9112 T9108 nsubj blastocysts,implant
R5569 T9113 T9108 prep into,implant
R5570 T9114 T9115 det the,uterus
R5571 T9115 T9113 pobj uterus,into
R5572 T9116 T9108 punct ", ",implant
R5573 T9117 T9108 cc but,implant
R5574 T9118 T9108 conj arrest,implant
R5575 T9119 T9120 advmod soon,after
R5576 T9120 T9118 prep after,arrest
R5577 T9121 T9120 pobj implantation,after
R5578 T9122 T9118 prep without,arrest
R5579 T9123 T9122 pcomp forming,without
R5580 T9124 T9125 amod organised,structures
R5581 T9125 T9123 dobj structures,forming
R5582 T9126 T9125 amod embryonic,structures
R5583 T9127 T9126 cc or,embryonic
R5584 T9128 T9126 conj extraembryonic,embryonic
R5585 T9129 T9130 punct [,27
R5586 T9130 T9093 parataxis 27,fail
R5587 T9131 T9130 punct ],27
R5588 T9132 T9093 punct .,fail
R5589 T9134 T9135 prep In,implant
R5590 T9136 T9134 pobj contrast,In
R5591 T9137 T9135 punct ", ",implant
R5592 T9138 T9139 compound Atrx,mutant
R5593 T9139 T9141 compound mutant,embryos
R5594 T9140 T9139 punct -,mutant
R5595 T9141 T9135 nsubj embryos,implant
R5596 T9142 T9135 advmod successfully,implant
R5597 T9143 T9135 cc and,implant
R5598 T9144 T9135 conj establish,implant
R5599 T9145 T9146 amod organised,structures
R5600 T9146 T9144 dobj structures,establish
R5601 T9147 T9146 amod embryonic,structures
R5602 T9148 T9144 prep by,establish
R5603 T9149 T9150 nummod 7.5,dpc
R5604 T9150 T9148 pobj dpc,by
R5605 T9151 T9135 punct .,implant
R5606 T9153 T9154 det The,phenotype
R5607 T9154 T9158 nsubj phenotype,resembles
R5608 T9155 T9156 compound Atrx,mutant
R5609 T9156 T9154 compound mutant,phenotype
R5610 T9157 T9156 punct -,mutant
R5611 T9159 T9158 advmod closely,resembles
R5612 T9160 T9158 dobj that,resembles
R5613 T9161 T9160 acl observed,that
R5614 T9162 T9161 prep in,observed
R5615 T9163 T9162 pobj mice,in
R5616 T9164 T9163 amod nullizygous,mice
R5617 T9165 T9164 prep for,nullizygous
R5618 T9166 T9167 det the,factor
R5619 T9167 T9165 pobj factor,for
R5620 T9168 T9167 amod basic,factor
R5621 T9169 T9170 compound helix,helix
R5622 T9170 T9167 compound helix,factor
R5623 T9171 T9170 punct -,helix
R5624 T9172 T9170 compound loop,helix
R5625 T9173 T9170 punct -,helix
R5626 T9174 T9167 compound transcription,factor
R5627 T9175 T9167 appos Hand1,factor
R5628 T9176 T9158 punct .,resembles
R5629 T9178 T9179 compound Hand1,mutant
R5630 T9179 T9181 compound mutant,conceptuses
R5631 T9180 T9179 punct -,mutant
R5632 T9181 T9182 nsubj conceptuses,arrest
R5633 T9183 T9182 prep at,arrest
R5634 T9184 T9185 quantmod around,7.5
R5635 T9185 T9186 nummod 7.5,dpc
R5636 T9186 T9183 pobj dpc,at
R5637 T9187 T9182 cc and,arrest
R5638 T9188 T9182 conj display,arrest
R5639 T9189 T9190 det a,compartment
R5640 T9190 T9188 dobj compartment,display
R5641 T9191 T9190 amod normal,compartment
R5642 T9192 T9190 amod embryonic,compartment
R5643 T9193 T9182 punct ", ",arrest
R5644 T9194 T9182 cc but,arrest
R5645 T9195 T9182 punct ", ",arrest
R5646 T9196 T9197 prep like,causes
R5647 T9197 T9182 conj causes,arrest
R5648 T9198 T9199 compound Atrx,mutant
R5649 T9199 T9201 compound mutant,embryos
R5650 T9200 T9199 punct -,mutant
R5651 T9201 T9196 pobj embryos,like
R5652 T9202 T9197 punct ", ",causes
R5653 T9203 T9197 nsubj ablation,causes
R5654 T9204 T9203 prep of,ablation
R5655 T9205 T9204 pobj Hand1,of
R5656 T9206 T9207 det a,reduction
R5657 T9207 T9197 dobj reduction,causes
R5658 T9208 T9207 prep in,reduction
R5659 T9209 T9210 det the,size
R5660 T9210 T9208 pobj size,in
R5661 T9211 T9210 prep of,size
R5662 T9212 T9213 det the,cone
R5663 T9213 T9211 pobj cone,of
R5664 T9214 T9213 amod ectoplacental,cone
R5665 T9215 T9210 cc and,size
R5666 T9216 T9210 conj density,size
R5667 T9217 T9216 prep of,density
R5668 T9218 T9217 pobj TGCs,of
R5669 T9219 T9220 punct [,28
R5670 T9220 T9197 parataxis 28,causes
R5671 T9221 T9220 punct ],28
R5672 T9222 T9197 punct .,causes
R5673 T9224 T9225 prep As,recovered
R5674 T9226 T9224 prep with,As
R5675 T9227 T9228 compound Atrx,mutants
R5676 T9228 T9226 pobj mutants,with
R5677 T9229 T9225 punct ", ",recovered
R5678 T9230 T9231 advmod only,conceptuses
R5679 T9231 T9225 nsubjpass conceptuses,recovered
R5680 T9232 T9231 amod arrested,conceptuses
R5681 T9233 T9232 cc or,arrested
R5682 T9234 T9232 conj resorbed,arrested
R5683 T9235 T9236 compound Hand1,mutant
R5684 T9236 T9231 compound mutant,conceptuses
R5685 T9237 T9236 punct -,mutant
R5686 T9238 T9225 auxpass were,recovered
R5687 T9239 T9225 prep after,recovered
R5688 T9240 T9241 nummod 8.5,dpc
R5689 T9241 T9239 pobj dpc,after
R5690 T9242 T9225 punct .,recovered
R5691 T9244 T9245 advmod Also,affects
R5692 T9246 T9245 prep like,affects
R5693 T9247 T9246 pobj Atrx,like
R5694 T9248 T9245 punct ", ",affects
R5695 T9249 T9245 nsubj disruption,affects
R5696 T9250 T9249 prep of,disruption
R5697 T9251 T9250 pobj Hand1,of
R5698 T9252 T9245 advmod specifically,affects
R5699 T9253 T9254 amod secondary,cell
R5700 T9254 T9256 compound cell,formation
R5701 T9255 T9254 amod giant,cell
R5702 T9256 T9245 dobj formation,affects
R5703 T9257 T9245 punct ", ",affects
R5704 T9258 T9245 cc and,affects
R5705 T9259 T9260 amod primary,outgrowths
R5706 T9260 T9262 nsubj outgrowths,appeared
R5707 T9261 T9260 compound trophoblast,outgrowths
R5708 T9262 T9245 conj appeared,affects
R5709 T9263 T9260 prep from,outgrowths
R5710 T9264 T9263 pobj blastocysts,from
R5711 T9265 T9262 oprd normal,appeared
R5712 T9266 T9262 punct .,appeared
R5713 T9268 T9269 nsubjpass Hand1,required
R5714 T9270 T9269 auxpass is,required
R5715 T9271 T9269 prep for,required
R5716 T9272 T9273 amod terminal,differentiation
R5717 T9273 T9271 pobj differentiation,for
R5718 T9274 T9273 prep of,differentiation
R5719 T9275 T9276 amod secondary,TGCs
R5720 T9276 T9274 pobj TGCs,of
R5721 T9277 T9269 punct ", ",required
R5722 T9278 T9269 cc and,required
R5723 T9279 T9280 prep in,arrest
R5724 T9280 T9269 conj arrest,required
R5725 T9281 T9282 poss its,absence
R5726 T9282 T9279 pobj absence,in
R5727 T9283 T9284 compound trophoblast,cells
R5728 T9284 T9280 nsubj cells,arrest
R5729 T9285 T9280 prep at,arrest
R5730 T9286 T9287 det a,stage
R5731 T9287 T9285 pobj stage,at
R5732 T9288 T9287 compound precursor,stage
R5733 T9289 T9280 prep in,arrest
R5734 T9290 T9291 det the,cone
R5735 T9291 T9289 pobj cone,in
R5736 T9292 T9291 amod ectoplacental,cone
R5737 T9293 T9294 punct [,28
R5738 T9294 T9280 parataxis 28,arrest
R5739 T9295 T9294 nummod 17,28
R5740 T9296 T9294 punct ",",28
R5741 T9297 T9294 punct ],28
R5742 T9298 T9280 punct .,arrest
R5743 T9300 T9301 prep Given,be
R5744 T9302 T9303 det the,similarity
R5745 T9303 T9300 pobj similarity,Given
R5746 T9304 T9303 prep of,similarity
R5747 T9305 T9306 det the,phenotypes
R5748 T9306 T9304 pobj phenotypes,of
R5749 T9307 T9308 nmod Atrx,mutant
R5750 T9308 T9306 compound mutant,phenotypes
R5751 T9309 T9307 punct -,Atrx
R5752 T9310 T9307 cc and,Atrx
R5753 T9311 T9307 conj Hand1,Atrx
R5754 T9312 T9308 punct -,mutant
R5755 T9313 T9303 cc and,similarity
R5756 T9314 T9315 det the,likelihood
R5757 T9315 T9303 conj likelihood,similarity
R5758 T9316 T9317 mark that,acts
R5759 T9317 T9315 acl acts,likelihood
R5760 T9318 T9317 nsubj Atrx,acts
R5761 T9319 T9317 prep as,acts
R5762 T9320 T9321 det a,regulator
R5763 T9321 T9319 pobj regulator,as
R5764 T9322 T9321 amod transcriptional,regulator
R5765 T9323 T9317 prep by,acts
R5766 T9324 T9323 pcomp modifying,by
R5767 T9325 T9326 compound chromatin,structure
R5768 T9326 T9324 dobj structure,modifying
R5769 T9327 T9301 punct ", ",be
R5770 T9328 T9301 nsubj it,be
R5771 T9329 T9301 aux will,be
R5772 T9330 T9301 prep of,be
R5773 T9331 T9330 pobj interest,of
R5774 T9332 T9333 aux to,determine
R5775 T9333 T9301 xcomp determine,be
R5776 T9334 T9335 mark whether,is
R5777 T9335 T9333 advcl is,determine
R5778 T9336 T9335 nsubj Atrx,is
R5779 T9337 T9335 npadvmod itself,is
R5780 T9338 T9339 det a,regulator
R5781 T9339 T9335 attr regulator,is
R5782 T9340 T9339 prep of,regulator
R5783 T9341 T9342 compound Hand1,expression
R5784 T9342 T9340 pobj expression,of
R5785 T9343 T9335 punct ", ",is
R5786 T9344 T9335 cc or,is
R5787 T9345 T9346 advmod alternatively,acts
R5788 T9346 T9335 conj acts,is
R5789 T9347 T9346 mark whether,acts
R5790 T9348 T9346 nsubj it,acts
R5791 T9349 T9346 prep as,acts
R5792 T9350 T9351 det a,co-regulator
R5793 T9351 T9349 pobj co-regulator,as
R5794 T9352 T9351 prep of,co-regulator
R5795 T9353 T9352 pobj one,of
R5796 T9354 T9353 cc or,one
R5797 T9355 T9353 conj more,one
R5798 T9356 T9353 prep of,one
R5799 T9357 T9358 det the,targets
R5800 T9358 T9356 pobj targets,of
R5801 T9359 T9358 amod downstream,targets
R5802 T9360 T9358 amod transcriptional,targets
R5803 T9361 T9358 prep of,targets
R5804 T9362 T9361 pobj Hand1,of
R5805 T9363 T9301 punct .,be
R5806 T9365 T9366 nsubj It,is
R5807 T9367 T9366 acomp noteworthy,is
R5808 T9368 T9369 mark that,observed
R5809 T9369 T9366 ccomp observed,is
R5810 T9370 T9369 punct ", ",observed
R5811 T9371 T9369 prep in,observed
R5812 T9372 T9373 det the,mice
R5813 T9373 T9371 pobj mice,in
R5814 T9374 T9375 npadvmod brain,specific
R5815 T9375 T9373 amod specific,mice
R5816 T9376 T9375 punct -,specific
R5817 T9377 T9378 compound Atrx,knockout
R5818 T9378 T9373 compound knockout,mice
R5819 T9379 T9369 punct ", ",observed
R5820 T9380 T9381 det the,defect
R5821 T9381 T9369 nsubjpass defect,observed
R5822 T9382 T9369 auxpass was,observed
R5823 T9383 T9369 prep in,observed
R5824 T9384 T9385 advmod terminally,differentiating
R5825 T9385 T9386 amod differentiating,neurons
R5826 T9386 T9383 pobj neurons,in
R5827 T9387 T9388 punct [,20
R5828 T9388 T9366 parataxis 20,is
R5829 T9389 T9388 punct ],20
R5830 T9390 T9366 punct .,is
R5831 T9392 T9393 det The,TGCs
R5832 T9393 T9395 nsubj TGCs,represent
R5833 T9394 T9393 amod secondary,TGCs
R5834 T9396 T9393 acl affected,TGCs
R5835 T9397 T9396 prep in,affected
R5836 T9398 T9399 det the,knockout
R5837 T9399 T9397 pobj knockout,in
R5838 T9400 T9399 amod universal,knockout
R5839 T9401 T9399 compound Atrx,knockout
R5840 T9402 T9399 acl reported,knockout
R5841 T9403 T9402 advmod here,reported
R5842 T9404 T9395 dobj one,represent
R5843 T9405 T9404 prep of,one
R5844 T9406 T9407 det the,tissues
R5845 T9407 T9405 pobj tissues,of
R5846 T9408 T9407 amod first,tissues
R5847 T9409 T9410 advmod terminally,differentiated
R5848 T9410 T9407 amod differentiated,tissues
R5849 T9411 T9404 prep in,one
R5850 T9412 T9413 det the,mouse
R5851 T9413 T9411 pobj mouse,in
R5852 T9414 T9413 amod developing,mouse
R5853 T9415 T9395 punct ", ",represent
R5854 T9416 T9395 cc and,represent
R5855 T9417 T9418 nsubj this,point
R5856 T9418 T9395 conj point,represent
R5857 T9419 T9418 aux may,point
R5858 T9420 T9418 prep to,point
R5859 T9421 T9422 det the,requirement
R5860 T9422 T9420 pobj requirement,to
R5861 T9423 T9422 prep for,requirement
R5862 T9424 T9423 pobj Atrx,for
R5863 T9425 T9422 prep in,requirement
R5864 T9426 T9427 det the,expression
R5865 T9427 T9425 pobj expression,in
R5866 T9428 T9429 amod high,level
R5867 T9429 T9427 compound level,expression
R5868 T9430 T9429 punct -,level
R5869 T9431 T9427 prep of,expression
R5870 T9432 T9433 det some,genes
R5871 T9433 T9431 pobj genes,of
R5872 T9434 T9435 npadvmod tissue,specific
R5873 T9435 T9433 amod specific,genes
R5874 T9436 T9435 punct -,specific
R5875 T9437 T9422 prep during,requirement
R5876 T9438 T9439 det the,stages
R5877 T9439 T9437 pobj stages,during
R5878 T9440 T9439 amod final,stages
R5879 T9441 T9439 prep of,stages
R5880 T9442 T9441 pobj differentiation,of
R5881 T9443 T9418 punct .,point
R5882 T9445 T9446 advmod Interestingly,expressed
R5883 T9447 T9446 punct ", ",expressed
R5884 T9448 T9449 det the,genes
R5885 T9449 T9446 nsubjpass genes,expressed
R5886 T9450 T9451 compound α,globin
R5887 T9451 T9449 compound globin,genes
R5888 T9452 T9451 punct -,globin
R5889 T9453 T9449 punct ", ",genes
R5890 T9454 T9455 det the,targets
R5891 T9455 T9449 appos targets,genes
R5892 T9456 T9455 advmod only,targets
R5893 T9457 T9455 amod confirmed,targets
R5894 T9458 T9455 amod transcriptional,targets
R5895 T9459 T9455 prep of,targets
R5896 T9460 T9459 pobj regulation,of
R5897 T9461 T9460 prep by,regulation
R5898 T9462 T9463 amod human,ATRX
R5899 T9463 T9461 pobj ATRX,by
R5900 T9464 T9446 punct ", ",expressed
R5901 T9465 T9446 auxpass are,expressed
R5902 T9466 T9446 advmod also,expressed
R5903 T9467 T9446 advmod highly,expressed
R5904 T9468 T9469 advmod specifically,during
R5905 T9469 T9446 prep during,expressed
R5906 T9470 T9471 amod terminal,differentiation
R5907 T9471 T9469 pobj differentiation,during
R5908 T9472 T9446 prep within,expressed
R5909 T9473 T9474 det the,lineage
R5910 T9474 T9472 pobj lineage,within
R5911 T9475 T9474 amod erythroid,lineage
R5912 T9476 T9446 punct .,expressed

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T8202 0-4 PR_EXT:000004503 denotes Atrx
T8203 32-37 NCBITaxon:10088 denotes mouse
T8204 38-43 SO_EXT:0000704 denotes genes
T8205 90-102 GO:0007566 denotes implantation
T8206 103-112 GO_EXT:fatality_or_lethality denotes lethality
T8207 128-139 UBERON:0000088 denotes trophoblast
T8208 143-152 UBERON:0001987 denotes placental
T8209 264-268 PR_EXT:000004503 denotes Atrx
T8210 272-283 UBERON:0000088 denotes trophoblast
T8211 297-301 PR_EXT:000004503 denotes Atrx
T8212 302-308 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T8213 309-316 UBERON:0000922 denotes embryos
T8214 339-346 UBERON:0000922 denotes embryos
T8215 395-411 _FRAGMENT denotes specification of
T8216 424-434 GO:0048866 denotes stem cells
T8217 412-423 UBERON:0000088 denotes trophoblast
T8218 412-423 _FRAGMENT denotes trophoblast
T8219 429-434 CL:0000351 denotes cells
T8220 424-434 CL:0000034 denotes stem cells
T8221 429-434 CL_GO_EXT:cell denotes cells
T8222 444-448 PR_EXT:000005296 denotes Cdx2
T8223 456-465 CL:0000034 denotes stem cell
T8224 456-477 GO:0019827 denotes stem cell maintenance
T8225 456-465 _FRAGMENT denotes stem cell
T8226 482-495 GO:0072089 denotes proliferation
T8227 461-465 CL_GO_EXT:cell denotes cell
T8228 505-510 PR_EXT:000003463 denotes Eomes
T8229 513-517 PR_EXT:000005296 denotes Cdx2
T8230 518-524 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T8231 525-532 UBERON:0000922 denotes embryos
T8232 541-548 GO:0007566 denotes implant
T8233 553-556 GO:0016265 denotes die
T8234 593-598 PR_EXT:000003463 denotes Eomes
T8235 599-605 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T8236 606-617 UBERON:0000358 denotes blastocysts
T8237 618-625 GO:0007566 denotes implant
T8238 635-641 UBERON:0000995 denotes uterus
T8239 665-677 GO:0007566 denotes implantation
T8240 704-713 _FRAGMENT denotes embryonic
T8241 732-742 UBERON:0002050 denotes structures
T8242 717-742 UBERON:0000478 denotes extraembryonic structures
T8243 762-766 PR_EXT:000004503 denotes Atrx
T8244 767-773 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T8245 774-781 UBERON:0000922 denotes embryos
T8246 782-789 GO:0007566 denotes implant
T8247 827-847 UBERON:0002050 denotes embryonic structures
T8248 864-868 PR_EXT:000004503 denotes Atrx
T8249 869-875 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T8250 921-925 NCBITaxon:10088 denotes mice
T8251 946-951 CHEBI_EXT:22695 denotes basic
T8252 952-957 SO_EXT:0001114 denotes helix
T8253 963-968 SO_EXT:0001114 denotes helix
T8254 969-982 GO_EXT:transcription denotes transcription
T8255 969-989 GO_EXT:transcription_factor denotes transcription factor
T8256 990-995 PR_EXT:000008439 denotes Hand1
T8257 997-1002 PR_EXT:000008439 denotes Hand1
T8258 1003-1009 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T8259 1068-1077 UBERON:0000922 denotes embryonic
T8260 1101-1105 PR_EXT:000004503 denotes Atrx
T8261 1106-1112 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T8262 1113-1120 UBERON:0000922 denotes embryos
T8263 1134-1139 PR_EXT:000008439 denotes Hand1
T8264 1178-1196 UBERON:0004364 denotes ectoplacental cone
T8265 1212-1216 CL:0002488 denotes TGCs
T8266 1231-1235 PR_EXT:000004503 denotes Atrx
T8267 1236-1243 SO_EXT:sequence_altered_entity denotes mutants
T8268 1271-1276 PR_EXT:000008439 denotes Hand1
T8269 1277-1283 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T8270 1284-1295 UBERON:0004716 denotes conceptuses
T8271 1336-1340 PR_EXT:000004503 denotes Atrx
T8272 1356-1361 PR_EXT:000008439 denotes Hand1
T8273 1383-1403 CL:0002498 denotes secondary giant cell
T8274 1399-1403 CL_GO_EXT:cell denotes cell
T8275 1399-1413 GO:0048468 denotes cell formation
T8276 1427-1438 UBERON:0000088 denotes trophoblast
T8277 1455-1466 UBERON:0000358 denotes blastocysts
T8278 1484-1489 PR_EXT:000008439 denotes Hand1
T8279 1515-1530 GO_RO_EXT:developmental_differentiation_process denotes differentiation
T8280 1534-1548 CL:0002498 denotes secondary TGCs
T8281 1569-1580 UBERON:0000088 denotes trophoblast
T8282 1569-1586 CL:0000351 denotes trophoblast cells
T8283 1581-1586 CL_GO_EXT:cell denotes cells
T8284 1622-1640 UBERON:0004364 denotes ectoplacental cone
T8285 1678-1682 PR_EXT:000004503 denotes Atrx
T8286 1688-1693 PR_EXT:000008439 denotes Hand1
T8287 1694-1700 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T8288 1736-1740 PR_EXT:000004503 denotes Atrx
T8289 1751-1766 GO_EXT:transcription denotes transcriptional
T8290 1767-1776 GO_EXT:regulator denotes regulator
T8291 1790-1799 GO:0000785 denotes chromatin
T8292 1855-1859 PR_EXT:000004503 denotes Atrx
T8293 1872-1881 GO_EXT:regulator denotes regulator
T8294 1885-1890 PR_EXT:000008439 denotes Hand1
T8295 1891-1901 GO:0010467 denotes expression
T8296 1944-1953 GO_EXT:regulator denotes regulator
T8297 1987-2002 GO_EXT:transcription denotes transcriptional
T8298 2014-2019 PR_EXT:000008439 denotes Hand1
T8299 2051-2056 UBERON:0000955 denotes brain
T8300 2066-2070 PR_EXT:000004503 denotes Atrx
T8301 2080-2084 NCBITaxon:10088 denotes mice
T8302 2124-2139 GO_RO_EXT:developmental_differentiation_process denotes differentiating
T8303 2140-2147 CL:0000540 denotes neurons
T8304 2158-2172 CL:0002498 denotes secondary TGCs
T8305 2199-2203 PR_EXT:000004503 denotes Atrx
T8306 2265-2279 GO_PATO_RO_EXT:developmental_differentiation_process_or_quality denotes differentiated
T8307 2280-2287 UBERON:0000479 denotes tissues
T8308 2306-2311 NCBITaxon:10088 denotes mouse
T8309 2355-2359 PR_EXT:000004503 denotes Atrx
T8310 2378-2388 GO:0010467 denotes expression
T8311 2397-2403 UBERON:0000479 denotes tissue
T8312 2413-2418 SO_EXT:0000704 denotes genes
T8313 2446-2461 GO_RO_EXT:developmental_differentiation_process denotes differentiation
T8314 2484-2490 CHEBI:5386 denotes globin
T8315 2491-2496 SO_EXT:0000704 denotes genes
T8316 2517-2532 GO_EXT:transcription denotes transcriptional
T8317 2544-2554 GO:0065007 denotes regulation
T8318 2558-2563 NCBITaxon:9606 denotes human
T8319 2564-2568 PR_EXT:000004503 denotes ATRX
T8320 2586-2595 GO:0010467 denotes expressed
T8321 2625-2640 GO_RO_EXT:developmental_differentiation_process denotes differentiation
T8322 2652-2661 CL:0000764 denotes erythroid
R4820 T8216 T8215 _lexicallyChainedTo stem cells,specification of
R4821 T8219 T8218 _lexicallyChainedTo cells,trophoblast
R4822 T8226 T8225 _lexicallyChainedTo proliferation,stem cell
R4823 T8241 T8240 _lexicallyChainedTo structures,embryonic

2_test

Id Subject Object Predicate Lexical cue
16628246-11433360-85799766 181-183 11433360 denotes 25
16628246-9052785-85799767 582-584 9052785 denotes 26
16628246-10716450-85799768 744-746 10716450 denotes 27
16628246-9500551-85799769 1218-1220 9500551 denotes 28
16628246-10611232-85799770 1642-1644 10611232 denotes 17
16628246-9500551-85799771 1645-1647 9500551 denotes 28
16628246-15668733-85799772 2149-2151 15668733 denotes 20
T36669 181-183 11433360 denotes 25
T78131 582-584 9052785 denotes 26
T46656 744-746 10716450 denotes 27
T27799 1218-1220 9500551 denotes 28
T13124 1642-1644 10611232 denotes 17
T42247 1645-1647 9500551 denotes 28
T83367 2149-2151 15668733 denotes 20

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T7969 0-4 PR:000004503 denotes Atrx
T7970 32-37 NCBITaxon:10088 denotes mouse
T7971 38-43 SO:0000704 denotes genes
T7972 90-102 GO:0007566 denotes implantation
T7973 128-139 UBERON:0000088 denotes trophoblast
T7974 143-152 UBERON:0001987 denotes placental
T7975 264-268 PR:000004503 denotes Atrx
T7976 272-283 UBERON:0000088 denotes trophoblast
T7977 297-301 PR:000004503 denotes Atrx
T7978 309-316 UBERON:0000922 denotes embryos
T7979 339-346 UBERON:0000922 denotes embryos
T7980 395-411 _FRAGMENT denotes specification of
T7981 424-434 GO:0048866 denotes stem cells
T7982 412-423 UBERON:0000088 denotes trophoblast
T7983 412-423 _FRAGMENT denotes trophoblast
T7984 429-434 CL:0000351 denotes cells
T7985 424-434 CL:0000034 denotes stem cells
T7986 444-448 PR:000005296 denotes Cdx2
T7987 456-465 CL:0000034 denotes stem cell
T7988 456-477 GO:0019827 denotes stem cell maintenance
T7989 456-465 _FRAGMENT denotes stem cell
T7990 482-495 GO:0072089 denotes proliferation
T7991 505-510 PR:000003463 denotes Eomes
T7992 513-517 PR:000005296 denotes Cdx2
T7993 525-532 UBERON:0000922 denotes embryos
T7994 541-548 GO:0007566 denotes implant
T7995 553-556 GO:0016265 denotes die
T7996 593-598 PR:000003463 denotes Eomes
T7997 606-617 UBERON:0000358 denotes blastocysts
T7998 618-625 GO:0007566 denotes implant
T7999 635-641 UBERON:0000995 denotes uterus
T8000 665-677 GO:0007566 denotes implantation
T8001 704-713 _FRAGMENT denotes embryonic
T8002 732-742 UBERON:0002050 denotes structures
T8003 717-742 UBERON:0000478 denotes extraembryonic structures
T8004 762-766 PR:000004503 denotes Atrx
T8005 774-781 UBERON:0000922 denotes embryos
T8006 782-789 GO:0007566 denotes implant
T8007 827-847 UBERON:0002050 denotes embryonic structures
T8008 864-868 PR:000004503 denotes Atrx
T8009 921-925 NCBITaxon:10088 denotes mice
T8010 946-951 CHEBI:22695 denotes basic
T8011 952-957 SO:0001114 denotes helix
T8012 963-968 SO:0001114 denotes helix
T8013 990-995 PR:000008439 denotes Hand1
T8014 997-1002 PR:000008439 denotes Hand1
T8015 1068-1077 UBERON:0000922 denotes embryonic
T8016 1101-1105 PR:000004503 denotes Atrx
T8017 1113-1120 UBERON:0000922 denotes embryos
T8018 1134-1139 PR:000008439 denotes Hand1
T8019 1178-1196 UBERON:0004364 denotes ectoplacental cone
T8020 1212-1216 CL:0002488 denotes TGCs
T8021 1231-1235 PR:000004503 denotes Atrx
T8022 1271-1276 PR:000008439 denotes Hand1
T8023 1284-1295 UBERON:0004716 denotes conceptuses
T8024 1336-1340 PR:000004503 denotes Atrx
T8025 1356-1361 PR:000008439 denotes Hand1
T8026 1383-1403 CL:0002498 denotes secondary giant cell
T8027 1399-1413 GO:0048468 denotes cell formation
T8028 1427-1438 UBERON:0000088 denotes trophoblast
T8029 1455-1466 UBERON:0000358 denotes blastocysts
T8030 1484-1489 PR:000008439 denotes Hand1
T8031 1534-1548 CL:0002498 denotes secondary TGCs
T8032 1569-1580 UBERON:0000088 denotes trophoblast
T8033 1569-1586 CL:0000351 denotes trophoblast cells
T8034 1622-1640 UBERON:0004364 denotes ectoplacental cone
T8035 1678-1682 PR:000004503 denotes Atrx
T8036 1688-1693 PR:000008439 denotes Hand1
T8037 1736-1740 PR:000004503 denotes Atrx
T8038 1790-1799 GO:0000785 denotes chromatin
T8039 1855-1859 PR:000004503 denotes Atrx
T8040 1885-1890 PR:000008439 denotes Hand1
T8041 1891-1901 GO:0010467 denotes expression
T8042 2014-2019 PR:000008439 denotes Hand1
T8043 2051-2056 UBERON:0000955 denotes brain
T8044 2066-2070 PR:000004503 denotes Atrx
T8045 2080-2084 NCBITaxon:10088 denotes mice
T8046 2140-2147 CL:0000540 denotes neurons
T8047 2158-2172 CL:0002498 denotes secondary TGCs
T8048 2199-2203 PR:000004503 denotes Atrx
T8049 2280-2287 UBERON:0000479 denotes tissues
T8050 2306-2311 NCBITaxon:10088 denotes mouse
T8051 2355-2359 PR:000004503 denotes Atrx
T8052 2378-2388 GO:0010467 denotes expression
T8053 2397-2403 UBERON:0000479 denotes tissue
T8054 2413-2418 SO:0000704 denotes genes
T8055 2484-2490 CHEBI:5386 denotes globin
T8056 2491-2496 SO:0000704 denotes genes
T8057 2544-2554 GO:0065007 denotes regulation
T8058 2558-2563 NCBITaxon:9606 denotes human
T8059 2564-2568 PR:000004503 denotes ATRX
T8060 2586-2595 GO:0010467 denotes expressed
T8061 2652-2661 CL:0000764 denotes erythroid
R4817 T7990 T7989 _lexicallyChainedTo proliferation,stem cell
R4818 T8002 T8001 _lexicallyChainedTo structures,embryonic
R4815 T7981 T7980 _lexicallyChainedTo stem cells,specification of
R4816 T7984 T7983 _lexicallyChainedTo cells,trophoblast