> top > docs > PMC:1440874 > spans > 31797-33432

PMC:1440874 / 31797-33432 JSON TXT

Annnotations TAB JSON ListView MergeView

craft-sa-dev

{"project":"craft-sa-dev","denotations":[{"id":"T6498","span":{"begin":0,"end":6},"obj":"JJ"},{"id":"T6499","span":{"begin":7,"end":11},"obj":"NNS"},{"id":"T6500","span":{"begin":75,"end":83},"obj":"VBN"},{"id":"T6501","span":{"begin":12,"end":20},"obj":"VBG"},{"id":"T6502","span":{"begin":21,"end":23},"obj":"DT"},{"id":"T6503","span":{"begin":34,"end":40},"obj":"NN"},{"id":"T6504","span":{"begin":24,"end":33},"obj":"JJ"},{"id":"T6505","span":{"begin":41,"end":42},"obj":"-LRB-"},{"id":"T6506","span":{"begin":61,"end":64},"obj":"NN"},{"id":"T6507","span":{"begin":42,"end":49},"obj":"NN"},{"id":"T6508","span":{"begin":50,"end":54},"obj":"NN"},{"id":"T6509","span":{"begin":49,"end":50},"obj":"HYPH"},{"id":"T6510","span":{"begin":54,"end":55},"obj":":"},{"id":"T6511","span":{"begin":55,"end":60},"obj":"NN"},{"id":"T6512","span":{"begin":60,"end":61},"obj":"HYPH"},{"id":"T6513","span":{"begin":65,"end":66},"obj":"SYM"},{"id":"T6514","span":{"begin":66,"end":67},"obj":"HYPH"},{"id":"T6515","span":{"begin":67,"end":68},"obj":"SYM"},{"id":"T6516","span":{"begin":68,"end":69},"obj":"-RRB-"},{"id":"T6517","span":{"begin":70,"end":74},"obj":"VBD"},{"id":"T6518","span":{"begin":84,"end":86},"obj":"IN"},{"id":"T6519","span":{"begin":87,"end":90},"obj":"CD"},{"id":"T6520","span":{"begin":91,"end":94},"obj":"NN"},{"id":"T6521","span":{"begin":95,"end":96},"obj":"-LRB-"},{"id":"T6522","span":{"begin":96,"end":101},"obj":"NN"},{"id":"T6523","span":{"begin":102,"end":103},"obj":"CD"},{"id":"T6524","span":{"begin":103,"end":104},"obj":"-RRB-"},{"id":"T6525","span":{"begin":105,"end":108},"obj":"CC"},{"id":"T6526","span":{"begin":109,"end":118},"obj":"VBN"},{"id":"T6527","span":{"begin":119,"end":121},"obj":"IN"},{"id":"T6528","span":{"begin":122,"end":127},"obj":"NN"},{"id":"T6529","span":{"begin":128,"end":129},"obj":"-LRB-"},{"id":"T6530","span":{"begin":141,"end":145},"obj":"NNS"},{"id":"T6531","span":{"begin":129,"end":140},"obj":"JJ"},{"id":"T6532","span":{"begin":145,"end":146},"obj":"-RRB-"},{"id":"T6533","span":{"begin":146,"end":148},"obj":","},{"id":"T6534","span":{"begin":148,"end":156},"obj":"IN"},{"id":"T6535","span":{"begin":207,"end":210},"obj":"VBD"},{"id":"T6536","span":{"begin":157,"end":159},"obj":"IN"},{"id":"T6537","span":{"begin":160,"end":164},"obj":"CC"},{"id":"T6538","span":{"begin":170,"end":176},"obj":"NNS"},{"id":"T6539","span":{"begin":165,"end":169},"obj":"NN"},{"id":"T6540","span":{"begin":177,"end":180},"obj":"DT"},{"id":"T6541","span":{"begin":181,"end":187},"obj":"NN"},{"id":"T6542","span":{"begin":188,"end":190},"obj":"IN"},{"id":"T6543","span":{"begin":191,"end":198},"obj":"NN"},{"id":"T6544","span":{"begin":199,"end":206},"obj":"NNS"},{"id":"T6545","span":{"begin":211,"end":216},"obj":"JJR"},{"id":"T6546","span":{"begin":217,"end":221},"obj":"IN"},{"id":"T6547","span":{"begin":222,"end":226},"obj":"DT"},{"id":"T6548","span":{"begin":227,"end":229},"obj":"IN"},{"id":"T6549","span":{"begin":230,"end":234},"obj":"JJ"},{"id":"T6550","span":{"begin":235,"end":239},"obj":"NN"},{"id":"T6551","span":{"begin":234,"end":235},"obj":"HYPH"},{"id":"T6552","span":{"begin":267,"end":274},"obj":"NNS"},{"id":"T6553","span":{"begin":240,"end":241},"obj":"-LRB-"},{"id":"T6554","span":{"begin":258,"end":261},"obj":"NN"},{"id":"T6555","span":{"begin":241,"end":248},"obj":"NN"},{"id":"T6556","span":{"begin":249,"end":251},"obj":"NN"},{"id":"T6557","span":{"begin":248,"end":249},"obj":"HYPH"},{"id":"T6558","span":{"begin":251,"end":252},"obj":":"},{"id":"T6559","span":{"begin":252,"end":257},"obj":"NN"},{"id":"T6560","span":{"begin":257,"end":258},"obj":"HYPH"},{"id":"T6561","span":{"begin":262,"end":263},"obj":"SYM"},{"id":"T6562","span":{"begin":263,"end":264},"obj":"HYPH"},{"id":"T6563","span":{"begin":264,"end":265},"obj":"SYM"},{"id":"T6564","span":{"begin":265,"end":266},"obj":"-RRB-"},{"id":"T6565","span":{"begin":274,"end":276},"obj":","},{"id":"T6566","span":{"begin":276,"end":286},"obj":"VBG"},{"id":"T6567","span":{"begin":287,"end":291},"obj":"IN"},{"id":"T6568","span":{"begin":331,"end":335},"obj":"VBD"},{"id":"T6569","span":{"begin":292,"end":293},"obj":"DT"},{"id":"T6570","span":{"begin":294,"end":304},"obj":"NN"},{"id":"T6571","span":{"begin":305,"end":307},"obj":"IN"},{"id":"T6572","span":{"begin":308,"end":315},"obj":"NN"},{"id":"T6573","span":{"begin":323,"end":330},"obj":"NNS"},{"id":"T6574","span":{"begin":316,"end":322},"obj":"JJ"},{"id":"T6575","span":{"begin":336,"end":338},"obj":"FW"},{"id":"T6576","span":{"begin":339,"end":344},"obj":"FW"},{"id":"T6577","span":{"begin":344,"end":345},"obj":"."},{"id":"T6578","span":{"begin":345,"end":489},"obj":"sentence"},{"id":"T6579","span":{"begin":346,"end":355},"obj":"VBG"},{"id":"T6580","span":{"begin":377,"end":381},"obj":"NNS"},{"id":"T6581","span":{"begin":356,"end":361},"obj":"JJ"},{"id":"T6582","span":{"begin":362,"end":369},"obj":"NN"},{"id":"T6583","span":{"begin":370,"end":376},"obj":"JJ"},{"id":"T6584","span":{"begin":382,"end":386},"obj":"VBD"},{"id":"T6585","span":{"begin":387,"end":390},"obj":"RB"},{"id":"T6586","span":{"begin":391,"end":405},"obj":"RB"},{"id":"T6587","span":{"begin":406,"end":412},"obj":"JJ"},{"id":"T6588","span":{"begin":413,"end":416},"obj":"CC"},{"id":"T6589","span":{"begin":417,"end":426},"obj":"VBD"},{"id":"T6590","span":{"begin":427,"end":431},"obj":"JJ"},{"id":"T6591","span":{"begin":444,"end":457},"obj":"NNS"},{"id":"T6592","span":{"begin":432,"end":443},"obj":"JJ"},{"id":"T6593","span":{"begin":457,"end":459},"obj":","},{"id":"T6594","span":{"begin":459,"end":467},"obj":"IN"},{"id":"T6595","span":{"begin":479,"end":488},"obj":"VB"},{"id":"T6596","span":{"begin":468,"end":472},"obj":"DT"},{"id":"T6597","span":{"begin":473,"end":478},"obj":"MD"},{"id":"T6598","span":{"begin":488,"end":489},"obj":"."},{"id":"T6599","span":{"begin":489,"end":649},"obj":"sentence"},{"id":"T6600","span":{"begin":490,"end":493},"obj":"IN"},{"id":"T6601","span":{"begin":590,"end":597},"obj":"VBN"},{"id":"T6602","span":{"begin":494,"end":497},"obj":"DT"},{"id":"T6603","span":{"begin":526,"end":533},"obj":"NNS"},{"id":"T6604","span":{"begin":498,"end":505},"obj":"NN"},{"id":"T6605","span":{"begin":506,"end":510},"obj":"JJ"},{"id":"T6606","span":{"begin":505,"end":506},"obj":"HYPH"},{"id":"T6607","span":{"begin":511,"end":518},"obj":"NN"},{"id":"T6608","span":{"begin":519,"end":525},"obj":"JJ"},{"id":"T6609","span":{"begin":534,"end":543},"obj":"VBN"},{"id":"T6610","span":{"begin":544,"end":546},"obj":"IN"},{"id":"T6611","span":{"begin":547,"end":552},"obj":"NN"},{"id":"T6612","span":{"begin":553,"end":554},"obj":"CD"},{"id":"T6613","span":{"begin":554,"end":556},"obj":","},{"id":"T6614","span":{"begin":556,"end":559},"obj":"DT"},{"id":"T6615","span":{"begin":568,"end":574},"obj":"NN"},{"id":"T6616","span":{"begin":560,"end":567},"obj":"NN"},{"id":"T6617","span":{"begin":575,"end":578},"obj":"VBD"},{"id":"T6618","span":{"begin":579,"end":589},"obj":"RB"},{"id":"T6619","span":{"begin":597,"end":599},"obj":","},{"id":"T6620","span":{"begin":599,"end":604},"obj":"IN"},{"id":"T6621","span":{"begin":641,"end":648},"obj":"VBN"},{"id":"T6622","span":{"begin":605,"end":608},"obj":"DT"},{"id":"T6623","span":{"begin":619,"end":625},"obj":"NN"},{"id":"T6624","span":{"begin":609,"end":618},"obj":"JJ"},{"id":"T6625","span":{"begin":626,"end":629},"obj":"VBD"},{"id":"T6626","span":{"begin":630,"end":640},"obj":"RB"},{"id":"T6627","span":{"begin":648,"end":649},"obj":"."},{"id":"T6628","span":{"begin":649,"end":888},"obj":"sentence"},{"id":"T6629","span":{"begin":650,"end":652},"obj":"IN"},{"id":"T6630","span":{"begin":690,"end":692},"obj":"VBZ"},{"id":"T6631","span":{"begin":653,"end":656},"obj":"DT"},{"id":"T6632","span":{"begin":657,"end":662},"obj":"NN"},{"id":"T6633","span":{"begin":662,"end":664},"obj":","},{"id":"T6634","span":{"begin":664,"end":665},"obj":"NN"},{"id":"T6635","span":{"begin":666,"end":676},"obj":"NN"},{"id":"T6636","span":{"begin":677,"end":689},"obj":"NN"},{"id":"T6637","span":{"begin":693,"end":700},"obj":"JJ"},{"id":"T6638","span":{"begin":701,"end":703},"obj":"IN"},{"id":"T6639","span":{"begin":704,"end":712},"obj":"JJ"},{"id":"T6640","span":{"begin":713,"end":723},"obj":"NN"},{"id":"T6641","span":{"begin":724,"end":726},"obj":"IN"},{"id":"T6642","span":{"begin":727,"end":730},"obj":"DT"},{"id":"T6643","span":{"begin":731,"end":744},"obj":"NN"},{"id":"T6644","span":{"begin":745,"end":748},"obj":"CC"},{"id":"T6645","span":{"begin":749,"end":758},"obj":"JJ"},{"id":"T6646","span":{"begin":768,"end":776},"obj":"NNS"},{"id":"T6647","span":{"begin":759,"end":767},"obj":"NN"},{"id":"T6648","span":{"begin":777,"end":781},"obj":"WDT"},{"id":"T6649","span":{"begin":782,"end":786},"obj":"VBP"},{"id":"T6650","span":{"begin":787,"end":791},"obj":"NN"},{"id":"T6651","span":{"begin":792,"end":794},"obj":"IN"},{"id":"T6652","span":{"begin":795,"end":798},"obj":"DT"},{"id":"T6653","span":{"begin":814,"end":821},"obj":"NNS"},{"id":"T6654","span":{"begin":799,"end":813},"obj":"JJ"},{"id":"T6655","span":{"begin":821,"end":823},"obj":","},{"id":"T6656","span":{"begin":823,"end":832},"obj":"VBG"},{"id":"T6657","span":{"begin":833,"end":835},"obj":"IN"},{"id":"T6658","span":{"begin":836,"end":848},"obj":"NN"},{"id":"T6659","span":{"begin":849,"end":851},"obj":"IN"},{"id":"T6660","span":{"begin":852,"end":855},"obj":"DT"},{"id":"T6661","span":{"begin":867,"end":877},"obj":"NN"},{"id":"T6662","span":{"begin":856,"end":864},"obj":"JJ"},{"id":"T6663","span":{"begin":865,"end":866},"obj":"NN"},{"id":"T6664","span":{"begin":878,"end":879},"obj":"-LRB-"},{"id":"T6665","span":{"begin":879,"end":881},"obj":"NN"},{"id":"T6666","span":{"begin":881,"end":882},"obj":"-RRB-"},{"id":"T6667","span":{"begin":883,"end":884},"obj":"-LRB-"},{"id":"T6668","span":{"begin":884,"end":886},"obj":"CD"},{"id":"T6669","span":{"begin":886,"end":887},"obj":"-RRB-"},{"id":"T6670","span":{"begin":887,"end":888},"obj":"."},{"id":"T6671","span":{"begin":888,"end":1017},"obj":"sentence"},{"id":"T6672","span":{"begin":889,"end":891},"obj":"IN"},{"id":"T6673","span":{"begin":1002,"end":1004},"obj":"VBZ"},{"id":"T6674","span":{"begin":892,"end":900},"obj":"NN"},{"id":"T6675","span":{"begin":900,"end":902},"obj":","},{"id":"T6676","span":{"begin":902,"end":904},"obj":"IN"},{"id":"T6677","span":{"begin":905,"end":912},"obj":"NNS"},{"id":"T6678","span":{"begin":913,"end":915},"obj":"IN"},{"id":"T6679","span":{"begin":916,"end":919},"obj":"DT"},{"id":"T6680","span":{"begin":920,"end":926},"obj":"NN"},{"id":"T6681","span":{"begin":927,"end":933},"obj":"JJ"},{"id":"T6682","span":{"begin":934,"end":935},"obj":"-LRB-"},{"id":"T6683","span":{"begin":935,"end":942},"obj":"VBN"},{"id":"T6684","span":{"begin":943,"end":947},"obj":"IN"},{"id":"T6685","span":{"begin":948,"end":951},"obj":"DT"},{"id":"T6686","span":{"begin":963,"end":967},"obj":"NN"},{"id":"T6687","span":{"begin":952,"end":957},"obj":"JJ"},{"id":"T6688","span":{"begin":958,"end":962},"obj":"NN"},{"id":"T6689","span":{"begin":968,"end":970},"obj":"IN"},{"id":"T6690","span":{"begin":971,"end":974},"obj":"DT"},{"id":"T6691","span":{"begin":975,"end":985},"obj":"NN"},{"id":"T6692","span":{"begin":985,"end":986},"obj":"-RRB-"},{"id":"T6693","span":{"begin":987,"end":988},"obj":"NN"},{"id":"T6694","span":{"begin":989,"end":1001},"obj":"NN"},{"id":"T6695","span":{"begin":988,"end":989},"obj":"HYPH"},{"id":"T6696","span":{"begin":1005,"end":1011},"obj":"JJ"},{"id":"T6697","span":{"begin":1012,"end":1013},"obj":"-LRB-"},{"id":"T6698","span":{"begin":1013,"end":1015},"obj":"CD"},{"id":"T6699","span":{"begin":1015,"end":1016},"obj":"-RRB-"},{"id":"T6700","span":{"begin":1016,"end":1017},"obj":"."},{"id":"T6701","span":{"begin":1017,"end":1350},"obj":"sentence"},{"id":"T6702","span":{"begin":1018,"end":1022},"obj":"RB"},{"id":"T6703","span":{"begin":1132,"end":1140},"obj":"VBN"},{"id":"T6704","span":{"begin":1022,"end":1024},"obj":","},{"id":"T6705","span":{"begin":1024,"end":1026},"obj":"IN"},{"id":"T6706","span":{"begin":1027,"end":1030},"obj":"DT"},{"id":"T6707","span":{"begin":1046,"end":1057},"obj":"NN"},{"id":"T6708","span":{"begin":1031,"end":1045},"obj":"JJ"},{"id":"T6709","span":{"begin":1058,"end":1060},"obj":"IN"},{"id":"T6710","span":{"begin":1061,"end":1068},"obj":"NN"},{"id":"T6711","span":{"begin":1069,"end":1073},"obj":"JJ"},{"id":"T6712","span":{"begin":1068,"end":1069},"obj":"HYPH"},{"id":"T6713","span":{"begin":1082,"end":1089},"obj":"NNS"},{"id":"T6714","span":{"begin":1074,"end":1081},"obj":"NN"},{"id":"T6715","span":{"begin":1089,"end":1091},"obj":","},{"id":"T6716","span":{"begin":1091,"end":1097},"obj":"JJ"},{"id":"T6717","span":{"begin":1110,"end":1122},"obj":"NN"},{"id":"T6718","span":{"begin":1098,"end":1107},"obj":"VBN"},{"id":"T6719","span":{"begin":1108,"end":1109},"obj":"NN"},{"id":"T6720","span":{"begin":1109,"end":1110},"obj":"HYPH"},{"id":"T6721","span":{"begin":1123,"end":1128},"obj":"MD"},{"id":"T6722","span":{"begin":1129,"end":1131},"obj":"VB"},{"id":"T6723","span":{"begin":1141,"end":1143},"obj":"TO"},{"id":"T6724","span":{"begin":1144,"end":1150},"obj":"VB"},{"id":"T6725","span":{"begin":1151,"end":1153},"obj":"IN"},{"id":"T6726","span":{"begin":1154,"end":1163},"obj":"VBG"},{"id":"T6727","span":{"begin":1164,"end":1166},"obj":"IN"},{"id":"T6728","span":{"begin":1167,"end":1170},"obj":"DT"},{"id":"T6729","span":{"begin":1198,"end":1204},"obj":"NN"},{"id":"T6730","span":{"begin":1171,"end":1181},"obj":"RB"},{"id":"T6731","span":{"begin":1182,"end":1189},"obj":"VBN"},{"id":"T6732","span":{"begin":1190,"end":1197},"obj":"NN"},{"id":"T6733","span":{"begin":1204,"end":1206},"obj":","},{"id":"T6734","span":{"begin":1206,"end":1213},"obj":"VBG"},{"id":"T6735","span":{"begin":1214,"end":1218},"obj":"RB"},{"id":"T6736","span":{"begin":1233,"end":1239},"obj":"NN"},{"id":"T6737","span":{"begin":1219,"end":1222},"obj":"DT"},{"id":"T6738","span":{"begin":1223,"end":1232},"obj":"JJ"},{"id":"T6739","span":{"begin":1240,"end":1242},"obj":"IN"},{"id":"T6740","span":{"begin":1243,"end":1246},"obj":"DT"},{"id":"T6741","span":{"begin":1263,"end":1264},"obj":"NN"},{"id":"T6742","span":{"begin":1247,"end":1253},"obj":"JJ"},{"id":"T6743","span":{"begin":1254,"end":1262},"obj":"JJ"},{"id":"T6744","span":{"begin":1265,"end":1266},"obj":"-LRB-"},{"id":"T6745","span":{"begin":1266,"end":1268},"obj":"NN"},{"id":"T6746","span":{"begin":1268,"end":1269},"obj":"-RRB-"},{"id":"T6747","span":{"begin":1270,"end":1273},"obj":"CC"},{"id":"T6748","span":{"begin":1274,"end":1281},"obj":"RB"},{"id":"T6749","span":{"begin":1282,"end":1288},"obj":"VB"},{"id":"T6750","span":{"begin":1289,"end":1292},"obj":"DT"},{"id":"T6751","span":{"begin":1308,"end":1315},"obj":"NNS"},{"id":"T6752","span":{"begin":1293,"end":1307},"obj":"JJ"},{"id":"T6753","span":{"begin":1316,"end":1320},"obj":"JJ"},{"id":"T6754","span":{"begin":1321,"end":1324},"obj":"IN"},{"id":"T6755","span":{"begin":1325,"end":1329},"obj":"JJ"},{"id":"T6756","span":{"begin":1330,"end":1336},"obj":"NN"},{"id":"T6757","span":{"begin":1329,"end":1330},"obj":"HYPH"},{"id":"T6758","span":{"begin":1342,"end":1349},"obj":"NN"},{"id":"T6759","span":{"begin":1337,"end":1341},"obj":"NN"},{"id":"T6760","span":{"begin":1349,"end":1350},"obj":"."},{"id":"T6761","span":{"begin":1350,"end":1445},"obj":"sentence"},{"id":"T6762","span":{"begin":1351,"end":1358},"obj":"RB"},{"id":"T6763","span":{"begin":1414,"end":1416},"obj":"VBZ"},{"id":"T6764","span":{"begin":1358,"end":1360},"obj":","},{"id":"T6765","span":{"begin":1360,"end":1363},"obj":"DT"},{"id":"T6766","span":{"begin":1364,"end":1371},"obj":"NN"},{"id":"T6767","span":{"begin":1372,"end":1374},"obj":"IN"},{"id":"T6768","span":{"begin":1375,"end":1379},"obj":"NN"},{"id":"T6769","span":{"begin":1380,"end":1382},"obj":"IN"},{"id":"T6770","span":{"begin":1383,"end":1386},"obj":"DT"},{"id":"T6771","span":{"begin":1402,"end":1413},"obj":"NN"},{"id":"T6772","span":{"begin":1387,"end":1401},"obj":"JJ"},{"id":"T6773","span":{"begin":1417,"end":1423},"obj":"JJ"},{"id":"T6774","span":{"begin":1424,"end":1426},"obj":"IN"},{"id":"T6775","span":{"begin":1427,"end":1436},"obj":"JJ"},{"id":"T6776","span":{"begin":1437,"end":1438},"obj":"NN"},{"id":"T6777","span":{"begin":1436,"end":1437},"obj":"HYPH"},{"id":"T6778","span":{"begin":1439,"end":1444},"obj":"NNS"},{"id":"T6779","span":{"begin":1444,"end":1445},"obj":"."},{"id":"T6780","span":{"begin":1445,"end":1635},"obj":"sentence"},{"id":"T6781","span":{"begin":1446,"end":1450},"obj":"DT"},{"id":"T6782","span":{"begin":1451,"end":1460},"obj":"VBD"},{"id":"T6783","span":{"begin":1461,"end":1464},"obj":"DT"},{"id":"T6784","span":{"begin":1465,"end":1476},"obj":"NN"},{"id":"T6785","span":{"begin":1477,"end":1479},"obj":"IN"},{"id":"T6786","span":{"begin":1480,"end":1482},"obj":"DT"},{"id":"T6787","span":{"begin":1483,"end":1489},"obj":"NN"},{"id":"T6788","span":{"begin":1490,"end":1494},"obj":"IN"},{"id":"T6789","span":{"begin":1495,"end":1504},"obj":"VBN"},{"id":"T6790","span":{"begin":1505,"end":1517},"obj":"NN"},{"id":"T6791","span":{"begin":1518,"end":1520},"obj":"IN"},{"id":"T6792","span":{"begin":1521,"end":1524},"obj":"DT"},{"id":"T6793","span":{"begin":1552,"end":1558},"obj":"NN"},{"id":"T6794","span":{"begin":1525,"end":1535},"obj":"RB"},{"id":"T6795","span":{"begin":1536,"end":1543},"obj":"VBN"},{"id":"T6796","span":{"begin":1544,"end":1551},"obj":"NN"},{"id":"T6797","span":{"begin":1559,"end":1561},"obj":"IN"},{"id":"T6798","span":{"begin":1562,"end":1565},"obj":"DT"},{"id":"T6799","span":{"begin":1581,"end":1592},"obj":"NN"},{"id":"T6800","span":{"begin":1566,"end":1580},"obj":"JJ"},{"id":"T6801","span":{"begin":1593,"end":1595},"obj":"IN"},{"id":"T6802","span":{"begin":1596,"end":1597},"obj":"DT"},{"id":"T6803","span":{"begin":1598,"end":1608},"obj":"NN"},{"id":"T6804","span":{"begin":1609,"end":1611},"obj":"IN"},{"id":"T6805","span":{"begin":1612,"end":1619},"obj":"NN"},{"id":"T6806","span":{"begin":1627,"end":1634},"obj":"NNS"},{"id":"T6807","span":{"begin":1620,"end":1626},"obj":"JJ"},{"id":"T6808","span":{"begin":1634,"end":1635},"obj":"."}],"relations":[{"id":"R3876","pred":"amod","subj":"T6498","obj":"T6499"},{"id":"R3877","pred":"nsubjpass","subj":"T6499","obj":"T6500"},{"id":"R3878","pred":"acl","subj":"T6501","obj":"T6499"},{"id":"R3879","pred":"det","subj":"T6502","obj":"T6503"},{"id":"R3880","pred":"dobj","subj":"T6503","obj":"T6501"},{"id":"R3881","pred":"amod","subj":"T6504","obj":"T6503"},{"id":"R3882","pred":"punct","subj":"T6505","obj":"T6506"},{"id":"R3883","pred":"parataxis","subj":"T6506","obj":"T6499"},{"id":"R3884","pred":"compound","subj":"T6507","obj":"T6508"},{"id":"R3885","pred":"dep","subj":"T6508","obj":"T6506"},{"id":"R3886","pred":"punct","subj":"T6509","obj":"T6508"},{"id":"R3887","pred":"punct","subj":"T6510","obj":"T6506"},{"id":"R3888","pred":"compound","subj":"T6511","obj":"T6506"},{"id":"R3889","pred":"punct","subj":"T6512","obj":"T6506"},{"id":"R3890","pred":"punct","subj":"T6513","obj":"T6506"},{"id":"R3891","pred":"punct","subj":"T6514","obj":"T6506"},{"id":"R3892","pred":"punct","subj":"T6515","obj":"T6506"},{"id":"R3893","pred":"punct","subj":"T6516","obj":"T6506"},{"id":"R3894","pred":"auxpass","subj":"T6517","obj":"T6500"},{"id":"R3895","pred":"prep","subj":"T6518","obj":"T6500"},{"id":"R3896","pred":"nummod","subj":"T6519","obj":"T6520"},{"id":"R3897","pred":"pobj","subj":"T6520","obj":"T6518"},{"id":"R3898","pred":"punct","subj":"T6521","obj":"T6522"},{"id":"R3899","pred":"parataxis","subj":"T6522","obj":"T6500"},{"id":"R3900","pred":"nummod","subj":"T6523","obj":"T6522"},{"id":"R3901","pred":"punct","subj":"T6524","obj":"T6522"},{"id":"R3902","pred":"cc","subj":"T6525","obj":"T6500"},{"id":"R3903","pred":"conj","subj":"T6526","obj":"T6500"},{"id":"R3904","pred":"prep","subj":"T6527","obj":"T6526"},{"id":"R3905","pred":"pobj","subj":"T6528","obj":"T6527"},{"id":"R3906","pred":"punct","subj":"T6529","obj":"T6530"},{"id":"R3907","pred":"meta","subj":"T6530","obj":"T6526"},{"id":"R3908","pred":"amod","subj":"T6531","obj":"T6530"},{"id":"R3909","pred":"punct","subj":"T6532","obj":"T6530"},{"id":"R3910","pred":"punct","subj":"T6533","obj":"T6500"},{"id":"R3911","pred":"mark","subj":"T6534","obj":"T6535"},{"id":"R3912","pred":"advcl","subj":"T6535","obj":"T6500"},{"id":"R3913","pred":"prep","subj":"T6536","obj":"T6535"},{"id":"R3914","pred":"preconj","subj":"T6537","obj":"T6538"},{"id":"R3915","pred":"pobj","subj":"T6538","obj":"T6536"},{"id":"R3916","pred":"compound","subj":"T6539","obj":"T6538"},{"id":"R3917","pred":"det","subj":"T6540","obj":"T6541"},{"id":"R3918","pred":"nsubj","subj":"T6541","obj":"T6535"},{"id":"R3919","pred":"prep","subj":"T6542","obj":"T6541"},{"id":"R3920","pred":"compound","subj":"T6543","obj":"T6544"},{"id":"R3921","pred":"pobj","subj":"T6544","obj":"T6542"},{"id":"R3922","pred":"acomp","subj":"T6545","obj":"T6535"},{"id":"R3923","pred":"prep","subj":"T6546","obj":"T6545"},{"id":"R3924","pred":"pobj","subj":"T6547","obj":"T6546"},{"id":"R3925","pred":"prep","subj":"T6548","obj":"T6547"},{"id":"R3926","pred":"amod","subj":"T6549","obj":"T6550"},{"id":"R3927","pred":"nmod","subj":"T6550","obj":"T6552"},{"id":"R3928","pred":"punct","subj":"T6551","obj":"T6550"},{"id":"R3929","pred":"pobj","subj":"T6552","obj":"T6548"},{"id":"R3930","pred":"punct","subj":"T6553","obj":"T6554"},{"id":"R3931","pred":"parataxis","subj":"T6554","obj":"T6550"},{"id":"R3932","pred":"compound","subj":"T6555","obj":"T6556"},{"id":"R3933","pred":"dep","subj":"T6556","obj":"T6554"},{"id":"R3934","pred":"punct","subj":"T6557","obj":"T6556"},{"id":"R3935","pred":"punct","subj":"T6558","obj":"T6554"},{"id":"R3936","pred":"compound","subj":"T6559","obj":"T6554"},{"id":"R3937","pred":"punct","subj":"T6560","obj":"T6554"},{"id":"R3938","pred":"punct","subj":"T6561","obj":"T6554"},{"id":"R3939","pred":"punct","subj":"T6562","obj":"T6554"},{"id":"R3940","pred":"punct","subj":"T6563","obj":"T6554"},{"id":"R3941","pred":"punct","subj":"T6564","obj":"T6554"},{"id":"R3942","pred":"punct","subj":"T6565","obj":"T6535"},{"id":"R3943","pred":"advcl","subj":"T6566","obj":"T6535"},{"id":"R3944","pred":"mark","subj":"T6567","obj":"T6568"},{"id":"R3945","pred":"ccomp","subj":"T6568","obj":"T6566"},{"id":"R3946","pred":"det","subj":"T6569","obj":"T6570"},{"id":"R3947","pred":"nsubj","subj":"T6570","obj":"T6568"},{"id":"R3948","pred":"prep","subj":"T6571","obj":"T6570"},{"id":"R3949","pred":"nmod","subj":"T6572","obj":"T6573"},{"id":"R3950","pred":"pobj","subj":"T6573","obj":"T6571"},{"id":"R3951","pred":"amod","subj":"T6574","obj":"T6573"},{"id":"R3952","pred":"advmod","subj":"T6575","obj":"T6576"},{"id":"R3953","pred":"advmod","subj":"T6576","obj":"T6568"},{"id":"R3954","pred":"punct","subj":"T6577","obj":"T6500"},{"id":"R3955","pred":"amod","subj":"T6579","obj":"T6580"},{"id":"R3956","pred":"nsubj","subj":"T6580","obj":"T6584"},{"id":"R3957","pred":"amod","subj":"T6581","obj":"T6580"},{"id":"R3958","pred":"nmod","subj":"T6582","obj":"T6580"},{"id":"R3959","pred":"amod","subj":"T6583","obj":"T6580"},{"id":"R3960","pred":"neg","subj":"T6585","obj":"T6584"},{"id":"R3961","pred":"advmod","subj":"T6586","obj":"T6587"},{"id":"R3962","pred":"acomp","subj":"T6587","obj":"T6584"},{"id":"R3963","pred":"cc","subj":"T6588","obj":"T6584"},{"id":"R3964","pred":"conj","subj":"T6589","obj":"T6584"},{"id":"R3965","pred":"amod","subj":"T6590","obj":"T6591"},{"id":"R3966","pred":"dobj","subj":"T6591","obj":"T6589"},{"id":"R3967","pred":"amod","subj":"T6592","obj":"T6591"},{"id":"R3968","pred":"punct","subj":"T6593","obj":"T6584"},{"id":"R3969","pred":"mark","subj":"T6594","obj":"T6595"},{"id":"R3970","pred":"advcl","subj":"T6595","obj":"T6584"},{"id":"R3971","pred":"nsubj","subj":"T6596","obj":"T6595"},{"id":"R3972","pred":"aux","subj":"T6597","obj":"T6595"},{"id":"R3973","pred":"punct","subj":"T6598","obj":"T6584"},{"id":"R3974","pred":"prep","subj":"T6600","obj":"T6601"},{"id":"R3975","pred":"det","subj":"T6602","obj":"T6603"},{"id":"R3976","pred":"pobj","subj":"T6603","obj":"T6600"},{"id":"R3977","pred":"npadvmod","subj":"T6604","obj":"T6605"},{"id":"R3978","pred":"amod","subj":"T6605","obj":"T6603"},{"id":"R3979","pred":"punct","subj":"T6606","obj":"T6605"},{"id":"R3980","pred":"nmod","subj":"T6607","obj":"T6603"},{"id":"R3981","pred":"amod","subj":"T6608","obj":"T6603"},{"id":"R3982","pred":"acl","subj":"T6609","obj":"T6603"},{"id":"R3983","pred":"prep","subj":"T6610","obj":"T6609"},{"id":"R3984","pred":"pobj","subj":"T6611","obj":"T6610"},{"id":"R3985","pred":"nummod","subj":"T6612","obj":"T6611"},{"id":"R3986","pred":"punct","subj":"T6613","obj":"T6601"},{"id":"R3987","pred":"det","subj":"T6614","obj":"T6615"},{"id":"R3988","pred":"nsubjpass","subj":"T6615","obj":"T6601"},{"id":"R3989","pred":"compound","subj":"T6616","obj":"T6615"},{"id":"R3990","pred":"auxpass","subj":"T6617","obj":"T6601"},{"id":"R3991","pred":"advmod","subj":"T6618","obj":"T6601"},{"id":"R3992","pred":"punct","subj":"T6619","obj":"T6601"},{"id":"R3993","pred":"mark","subj":"T6620","obj":"T6621"},{"id":"R3994","pred":"advcl","subj":"T6621","obj":"T6601"},{"id":"R3995","pred":"det","subj":"T6622","obj":"T6623"},{"id":"R3996","pred":"nsubjpass","subj":"T6623","obj":"T6621"},{"id":"R3997","pred":"amod","subj":"T6624","obj":"T6623"},{"id":"R3998","pred":"auxpass","subj":"T6625","obj":"T6621"},{"id":"R3999","pred":"advmod","subj":"T6626","obj":"T6621"},{"id":"R4000","pred":"punct","subj":"T6627","obj":"T6601"},{"id":"R4001","pred":"prep","subj":"T6629","obj":"T6630"},{"id":"R4002","pred":"det","subj":"T6631","obj":"T6632"},{"id":"R4003","pred":"pobj","subj":"T6632","obj":"T6629"},{"id":"R4004","pred":"punct","subj":"T6633","obj":"T6630"},{"id":"R4005","pred":"compound","subj":"T6634","obj":"T6635"},{"id":"R4006","pred":"compound","subj":"T6635","obj":"T6636"},{"id":"R4007","pred":"nsubj","subj":"T6636","obj":"T6630"},{"id":"R4008","pred":"acomp","subj":"T6637","obj":"T6630"},{"id":"R4009","pred":"prep","subj":"T6638","obj":"T6637"},{"id":"R4010","pred":"amod","subj":"T6639","obj":"T6640"},{"id":"R4011","pred":"pobj","subj":"T6640","obj":"T6638"},{"id":"R4012","pred":"prep","subj":"T6641","obj":"T6640"},{"id":"R4013","pred":"det","subj":"T6642","obj":"T6643"},{"id":"R4014","pred":"pobj","subj":"T6643","obj":"T6641"},{"id":"R4015","pred":"cc","subj":"T6644","obj":"T6643"},{"id":"R4016","pred":"amod","subj":"T6645","obj":"T6646"},{"id":"R4017","pred":"conj","subj":"T6646","obj":"T6643"},{"id":"R4018","pred":"compound","subj":"T6647","obj":"T6646"},{"id":"R4019","pred":"dep","subj":"T6648","obj":"T6649"},{"id":"R4020","pred":"relcl","subj":"T6649","obj":"T6643"},{"id":"R4021","pred":"dobj","subj":"T6650","obj":"T6649"},{"id":"R4022","pred":"prep","subj":"T6651","obj":"T6649"},{"id":"R4023","pred":"det","subj":"T6652","obj":"T6653"},{"id":"R4024","pred":"pobj","subj":"T6653","obj":"T6651"},{"id":"R4025","pred":"amod","subj":"T6654","obj":"T6653"},{"id":"R4026","pred":"punct","subj":"T6655","obj":"T6630"},{"id":"R4027","pred":"advcl","subj":"T6656","obj":"T6630"},{"id":"R4028","pred":"prep","subj":"T6657","obj":"T6656"},{"id":"R4029","pred":"pobj","subj":"T6658","obj":"T6657"},{"id":"R4030","pred":"prep","subj":"T6659","obj":"T6658"},{"id":"R4031","pred":"det","subj":"T6660","obj":"T6661"},{"id":"R4032","pred":"pobj","subj":"T6661","obj":"T6659"},{"id":"R4033","pred":"amod","subj":"T6662","obj":"T6663"},{"id":"R4034","pred":"compound","subj":"T6663","obj":"T6661"},{"id":"R4035","pred":"punct","subj":"T6664","obj":"T6661"},{"id":"R4036","pred":"appos","subj":"T6665","obj":"T6661"},{"id":"R4037","pred":"punct","subj":"T6666","obj":"T6661"},{"id":"R4038","pred":"punct","subj":"T6667","obj":"T6668"},{"id":"R4039","pred":"parataxis","subj":"T6668","obj":"T6630"},{"id":"R4040","pred":"punct","subj":"T6669","obj":"T6668"},{"id":"R4041","pred":"punct","subj":"T6670","obj":"T6630"},{"id":"R4042","pred":"prep","subj":"T6672","obj":"T6673"},{"id":"R4043","pred":"pobj","subj":"T6674","obj":"T6672"},{"id":"R4044","pred":"punct","subj":"T6675","obj":"T6673"},{"id":"R4045","pred":"prep","subj":"T6676","obj":"T6673"},{"id":"R4046","pred":"pobj","subj":"T6677","obj":"T6676"},{"id":"R4047","pred":"prep","subj":"T6678","obj":"T6677"},{"id":"R4048","pred":"det","subj":"T6679","obj":"T6680"},{"id":"R4049","pred":"pobj","subj":"T6680","obj":"T6678"},{"id":"R4050","pred":"amod","subj":"T6681","obj":"T6680"},{"id":"R4051","pred":"punct","subj":"T6682","obj":"T6677"},{"id":"R4052","pred":"acl","subj":"T6683","obj":"T6677"},{"id":"R4053","pred":"prep","subj":"T6684","obj":"T6683"},{"id":"R4054","pred":"det","subj":"T6685","obj":"T6686"},{"id":"R4055","pred":"pobj","subj":"T6686","obj":"T6684"},{"id":"R4056","pred":"amod","subj":"T6687","obj":"T6686"},{"id":"R4057","pred":"compound","subj":"T6688","obj":"T6686"},{"id":"R4058","pred":"prep","subj":"T6689","obj":"T6686"},{"id":"R4059","pred":"det","subj":"T6690","obj":"T6691"},{"id":"R4060","pred":"pobj","subj":"T6691","obj":"T6689"},{"id":"R4061","pred":"punct","subj":"T6692","obj":"T6673"},{"id":"R4062","pred":"compound","subj":"T6693","obj":"T6694"},{"id":"R4063","pred":"nsubj","subj":"T6694","obj":"T6673"},{"id":"R4064","pred":"punct","subj":"T6695","obj":"T6694"},{"id":"R4065","pred":"acomp","subj":"T6696","obj":"T6673"},{"id":"R4066","pred":"punct","subj":"T6697","obj":"T6698"},{"id":"R4067","pred":"parataxis","subj":"T6698","obj":"T6673"},{"id":"R4068","pred":"punct","subj":"T6699","obj":"T6698"},{"id":"R4069","pred":"punct","subj":"T6700","obj":"T6673"},{"id":"R4070","pred":"advmod","subj":"T6702","obj":"T6703"},{"id":"R4071","pred":"punct","subj":"T6704","obj":"T6703"},{"id":"R4072","pred":"prep","subj":"T6705","obj":"T6703"},{"id":"R4073","pred":"det","subj":"T6706","obj":"T6707"},{"id":"R4074","pred":"pobj","subj":"T6707","obj":"T6705"},{"id":"R4075","pred":"amod","subj":"T6708","obj":"T6707"},{"id":"R4076","pred":"prep","subj":"T6709","obj":"T6707"},{"id":"R4077","pred":"npadvmod","subj":"T6710","obj":"T6711"},{"id":"R4078","pred":"amod","subj":"T6711","obj":"T6713"},{"id":"R4079","pred":"punct","subj":"T6712","obj":"T6711"},{"id":"R4080","pred":"pobj","subj":"T6713","obj":"T6709"},{"id":"R4081","pred":"compound","subj":"T6714","obj":"T6713"},{"id":"R4082","pred":"punct","subj":"T6715","obj":"T6703"},{"id":"R4083","pred":"amod","subj":"T6716","obj":"T6717"},{"id":"R4084","pred":"nsubjpass","subj":"T6717","obj":"T6703"},{"id":"R4085","pred":"amod","subj":"T6718","obj":"T6717"},{"id":"R4086","pred":"compound","subj":"T6719","obj":"T6717"},{"id":"R4087","pred":"punct","subj":"T6720","obj":"T6717"},{"id":"R4088","pred":"aux","subj":"T6721","obj":"T6703"},{"id":"R4089","pred":"auxpass","subj":"T6722","obj":"T6703"},{"id":"R4090","pred":"aux","subj":"T6723","obj":"T6724"},{"id":"R4091","pred":"xcomp","subj":"T6724","obj":"T6703"},{"id":"R4092","pred":"prep","subj":"T6725","obj":"T6724"},{"id":"R4093","pred":"pobj","subj":"T6726","obj":"T6725"},{"id":"R4094","pred":"prep","subj":"T6727","obj":"T6726"},{"id":"R4095","pred":"det","subj":"T6728","obj":"T6729"},{"id":"R4096","pred":"pobj","subj":"T6729","obj":"T6727"},{"id":"R4097","pred":"advmod","subj":"T6730","obj":"T6731"},{"id":"R4098","pred":"amod","subj":"T6731","obj":"T6729"},{"id":"R4099","pred":"compound","subj":"T6732","obj":"T6729"},{"id":"R4100","pred":"punct","subj":"T6733","obj":"T6703"},{"id":"R4101","pred":"advcl","subj":"T6734","obj":"T6703"},{"id":"R4102","pred":"advmod","subj":"T6735","obj":"T6736"},{"id":"R4103","pred":"dobj","subj":"T6736","obj":"T6734"},{"id":"R4104","pred":"det","subj":"T6737","obj":"T6736"},{"id":"R4105","pred":"amod","subj":"T6738","obj":"T6736"},{"id":"R4106","pred":"prep","subj":"T6739","obj":"T6734"},{"id":"R4107","pred":"det","subj":"T6740","obj":"T6741"},{"id":"R4108","pred":"pobj","subj":"T6741","obj":"T6739"},{"id":"R4109","pred":"amod","subj":"T6742","obj":"T6741"},{"id":"R4110","pred":"amod","subj":"T6743","obj":"T6741"},{"id":"R4111","pred":"punct","subj":"T6744","obj":"T6741"},{"id":"R4112","pred":"appos","subj":"T6745","obj":"T6741"},{"id":"R4113","pred":"punct","subj":"T6746","obj":"T6734"},{"id":"R4114","pred":"cc","subj":"T6747","obj":"T6734"},{"id":"R4115","pred":"advmod","subj":"T6748","obj":"T6749"},{"id":"R4116","pred":"conj","subj":"T6749","obj":"T6734"},{"id":"R4117","pred":"det","subj":"T6750","obj":"T6751"},{"id":"R4118","pred":"dobj","subj":"T6751","obj":"T6749"},{"id":"R4119","pred":"amod","subj":"T6752","obj":"T6751"},{"id":"R4120","pred":"oprd","subj":"T6753","obj":"T6749"},{"id":"R4121","pred":"prep","subj":"T6754","obj":"T6753"},{"id":"R4122","pred":"amod","subj":"T6755","obj":"T6756"},{"id":"R4123","pred":"compound","subj":"T6756","obj":"T6758"},{"id":"R4124","pred":"punct","subj":"T6757","obj":"T6756"},{"id":"R4125","pred":"pobj","subj":"T6758","obj":"T6754"},{"id":"R4126","pred":"compound","subj":"T6759","obj":"T6758"},{"id":"R4127","pred":"punct","subj":"T6760","obj":"T6703"},{"id":"R4128","pred":"advmod","subj":"T6762","obj":"T6763"},{"id":"R4129","pred":"punct","subj":"T6764","obj":"T6763"},{"id":"R4130","pred":"det","subj":"T6765","obj":"T6766"},{"id":"R4131","pred":"nsubj","subj":"T6766","obj":"T6763"},{"id":"R4132","pred":"prep","subj":"T6767","obj":"T6766"},{"id":"R4133","pred":"pobj","subj":"T6768","obj":"T6767"},{"id":"R4134","pred":"prep","subj":"T6769","obj":"T6766"},{"id":"R4135","pred":"det","subj":"T6770","obj":"T6771"},{"id":"R4136","pred":"pobj","subj":"T6771","obj":"T6769"},{"id":"R4137","pred":"amod","subj":"T6772","obj":"T6771"},{"id":"R4138","pred":"acomp","subj":"T6773","obj":"T6763"},{"id":"R4139","pred":"prep","subj":"T6774","obj":"T6763"},{"id":"R4140","pred":"amod","subj":"T6775","obj":"T6776"},{"id":"R4141","pred":"compound","subj":"T6776","obj":"T6778"},{"id":"R4142","pred":"punct","subj":"T6777","obj":"T6776"},{"id":"R4143","pred":"pobj","subj":"T6778","obj":"T6774"},{"id":"R4144","pred":"punct","subj":"T6779","obj":"T6763"},{"id":"R4145","pred":"nsubj","subj":"T6781","obj":"T6782"},{"id":"R4146","pred":"det","subj":"T6783","obj":"T6784"},{"id":"R4147","pred":"dobj","subj":"T6784","obj":"T6782"},{"id":"R4148","pred":"prep","subj":"T6785","obj":"T6784"},{"id":"R4149","pred":"det","subj":"T6786","obj":"T6787"},{"id":"R4150","pred":"pobj","subj":"T6787","obj":"T6785"},{"id":"R4151","pred":"prep","subj":"T6788","obj":"T6787"},{"id":"R4152","pred":"amod","subj":"T6789","obj":"T6790"},{"id":"R4153","pred":"pobj","subj":"T6790","obj":"T6788"},{"id":"R4154","pred":"prep","subj":"T6791","obj":"T6790"},{"id":"R4155","pred":"det","subj":"T6792","obj":"T6793"},{"id":"R4156","pred":"pobj","subj":"T6793","obj":"T6791"},{"id":"R4157","pred":"advmod","subj":"T6794","obj":"T6795"},{"id":"R4158","pred":"amod","subj":"T6795","obj":"T6793"},{"id":"R4159","pred":"compound","subj":"T6796","obj":"T6793"},{"id":"R4160","pred":"prep","subj":"T6797","obj":"T6782"},{"id":"R4161","pred":"det","subj":"T6798","obj":"T6799"},{"id":"R4162","pred":"pobj","subj":"T6799","obj":"T6797"},{"id":"R4163","pred":"amod","subj":"T6800","obj":"T6799"},{"id":"R4164","pred":"prep","subj":"T6801","obj":"T6799"},{"id":"R4165","pred":"det","subj":"T6802","obj":"T6803"},{"id":"R4166","pred":"pobj","subj":"T6803","obj":"T6801"},{"id":"R4167","pred":"prep","subj":"T6804","obj":"T6803"},{"id":"R4168","pred":"nmod","subj":"T6805","obj":"T6806"},{"id":"R4169","pred":"pobj","subj":"T6806","obj":"T6804"},{"id":"R4170","pred":"amod","subj":"T6807","obj":"T6806"},{"id":"R4171","pred":"punct","subj":"T6808","obj":"T6782"}],"text":"Female mice carrying an Atrx null allele (Atrx WT/null;GATA1-cre +/−) were detected at 9.5 dpc (Table 1) and recovered at birth (unpublished data), although at both time points the number of carrier females was lower than that of wild-type (Atrx WT/WT;GATA1-cre +/−) females, suggesting that a proportion of carrier female embryos died in utero. Surviving adult carrier female mice were not phenotypically normal and exhibited mild behavioural abnormalities, although some could reproduce. For all Atrx WT/null carrier female embryos presented in Table 1, the Atrx WT allele was paternally derived, while the Atrx null allele was maternally derived. In the mouse, X chromosome inactivation is subject to parental imprinting in the trophectoderm and primitive endoderm lineages that give rise to the extraembryonic tissues, resulting in inactivation of the paternal X chromosome (Xp) [18]. In contrast, in tissues of the embryo proper (derived from the inner cell mass of the blastocyst) X-inactivation is random [19]. Thus, in the extraembryonic compartment of Atrx WT/null carrier females, normal imprinted X-inactivation would be expected to result in silencing of the paternally derived Atrx WT allele, leaving only the Atrx null allele on the active maternal X (Xm) and thereby render the extraembryonic tissues null for full-length Atrx protein. However, the absence of Atrx in the extraembryonic compartment is lethal in Atrx null/Y males. This suggested the possibility of an escape from imprinted inactivation of the paternally derived Atrx WT allele in the extraembryonic compartment of a proportion of carrier female embryos."}

craft-ca-core-ex-dev

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T6288","span":{"begin":0,"end":6},"obj":"PATO_UBERON_EXT:female_or_bearer_of_femaleness"},{"id":"T6289","span":{"begin":7,"end":11},"obj":"NCBITaxon:10088"},{"id":"T6290","span":{"begin":24,"end":28},"obj":"PR_EXT:000004503"},{"id":"T6291","span":{"begin":29,"end":33},"obj":"SO_EXT:sequence_nullness"},{"id":"T6292","span":{"begin":34,"end":40},"obj":"SO_EXT:0001023"},{"id":"T6293","span":{"begin":42,"end":46},"obj":"PR_EXT:000004503"},{"id":"T6294","span":{"begin":47,"end":49},"obj":"SO_EXT:wild_type_entity_or_quality"},{"id":"T6295","span":{"begin":50,"end":54},"obj":"SO_EXT:sequence_nullness"},{"id":"T6296","span":{"begin":55,"end":60},"obj":"PR_EXT:000007857"},{"id":"T6297","span":{"begin":65,"end":66},"obj":"SO_EXT:normal_or_wild_type_or_present"},{"id":"T6298","span":{"begin":67,"end":68},"obj":"SO_EXT:sequence_nullness_or_absence"},{"id":"T6299","span":{"begin":122,"end":127},"obj":"GO:0007567"},{"id":"T6300","span":{"begin":199,"end":206},"obj":"PATO_UBERON_EXT:female_or_bearer_of_femaleness"},{"id":"T6301","span":{"begin":230,"end":239},"obj":"SO_EXT:wild_type_entity_or_quality"},{"id":"T6302","span":{"begin":241,"end":245},"obj":"PR_EXT:000004503"},{"id":"T6303","span":{"begin":246,"end":248},"obj":"SO_EXT:wild_type_entity_or_quality"},{"id":"T6304","span":{"begin":249,"end":251},"obj":"SO_EXT:wild_type_entity_or_quality"},{"id":"T6305","span":{"begin":252,"end":257},"obj":"PR_EXT:000007857"},{"id":"T6306","span":{"begin":262,"end":263},"obj":"SO_EXT:normal_or_wild_type_or_present"},{"id":"T6307","span":{"begin":264,"end":265},"obj":"SO_EXT:sequence_nullness_or_absence"},{"id":"T6308","span":{"begin":267,"end":274},"obj":"PATO_UBERON_EXT:female_or_bearer_of_femaleness"},{"id":"T6309","span":{"begin":316,"end":322},"obj":"PATO_UBERON_EXT:female_or_bearer_of_femaleness"},{"id":"T6310","span":{"begin":323,"end":330},"obj":"UBERON:0000922"},{"id":"T6311","span":{"begin":331,"end":335},"obj":"GO:0016265"},{"id":"T6312","span":{"begin":356,"end":361},"obj":"UBERON:0007023"},{"id":"T6313","span":{"begin":370,"end":376},"obj":"PATO_UBERON_EXT:female_or_bearer_of_femaleness"},{"id":"T6314","span":{"begin":377,"end":381},"obj":"NCBITaxon:10088"},{"id":"T6315","span":{"begin":432,"end":443},"obj":"GO_PATO_EXT:biological_behavior"},{"id":"T6316","span":{"begin":479,"end":488},"obj":"GO:0000003"},{"id":"T6317","span":{"begin":498,"end":502},"obj":"PR_EXT:000004503"},{"id":"T6318","span":{"begin":503,"end":505},"obj":"SO_EXT:wild_type_entity_or_quality"},{"id":"T6319","span":{"begin":506,"end":510},"obj":"SO_EXT:sequence_nullness"},{"id":"T6320","span":{"begin":519,"end":525},"obj":"PATO_UBERON_EXT:female_or_bearer_of_femaleness"},{"id":"T6321","span":{"begin":526,"end":533},"obj":"UBERON:0000922"},{"id":"T6322","span":{"begin":560,"end":564},"obj":"PR_EXT:000004503"},{"id":"T6323","span":{"begin":565,"end":567},"obj":"SO_EXT:wild_type_entity_or_quality"},{"id":"T6324","span":{"begin":568,"end":574},"obj":"SO_EXT:0001023"},{"id":"T6325","span":{"begin":609,"end":613},"obj":"PR_EXT:000004503"},{"id":"T6326","span":{"begin":614,"end":618},"obj":"SO_EXT:sequence_nullness"},{"id":"T6327","span":{"begin":619,"end":625},"obj":"SO_EXT:0001023"},{"id":"T6328","span":{"begin":657,"end":662},"obj":"NCBITaxon:10088"},{"id":"T6329","span":{"begin":664,"end":676},"obj":"GO:0000805"},{"id":"T6330","span":{"begin":664,"end":689},"obj":"GO:0009048"},{"id":"T6331","span":{"begin":666,"end":676},"obj":"GO_SO_EXT:chromosome"},{"id":"T6332","span":{"begin":713,"end":723},"obj":"GO:0071514"},{"id":"T6333","span":{"begin":731,"end":744},"obj":"UBERON:0004345"},{"id":"T6334","span":{"begin":749,"end":767},"obj":"UBERON:0008776"},{"id":"T6335","span":{"begin":799,"end":821},"obj":"UBERON:0005292"},{"id":"T6336","span":{"begin":836,"end":851},"obj":"_FRAGMENT"},{"id":"T6337","span":{"begin":856,"end":877},"obj":"GO:0060817"},{"id":"T6338","span":{"begin":879,"end":881},"obj":"GO:0060817"},{"id":"T6339","span":{"begin":865,"end":877},"obj":"GO:0000805"},{"id":"T6340","span":{"begin":867,"end":877},"obj":"GO_SO_EXT:chromosome"},{"id":"T6341","span":{"begin":905,"end":912},"obj":"UBERON:0000479"},{"id":"T6342","span":{"begin":920,"end":926},"obj":"UBERON:0000922"},{"id":"T6343","span":{"begin":952,"end":967},"obj":"UBERON:0000087"},{"id":"T6344","span":{"begin":958,"end":962},"obj":"CL_GO_EXT:cell"},{"id":"T6345","span":{"begin":975,"end":985},"obj":"UBERON:0000358"},{"id":"T6346","span":{"begin":987,"end":988},"obj":"GO:0000805"},{"id":"T6347","span":{"begin":987,"end":1001},"obj":"GO:0009048"},{"id":"T6348","span":{"begin":1036,"end":1045},"obj":"UBERON:0000922"},{"id":"T6349","span":{"begin":1061,"end":1065},"obj":"PR_EXT:000004503"},{"id":"T6350","span":{"begin":1066,"end":1068},"obj":"SO_EXT:wild_type_entity_or_quality"},{"id":"T6351","span":{"begin":1069,"end":1073},"obj":"SO_EXT:sequence_nullness"},{"id":"T6352","span":{"begin":1082,"end":1089},"obj":"PATO_UBERON_EXT:female_or_bearer_of_femaleness"},{"id":"T6353","span":{"begin":1098,"end":1122},"obj":"GO:0060819"},{"id":"T6354","span":{"begin":1108,"end":1109},"obj":"GO:0000805"},{"id":"T6355","span":{"begin":1154,"end":1163},"obj":"GO:0016458"},{"id":"T6356","span":{"begin":1190,"end":1194},"obj":"PR_EXT:000004503"},{"id":"T6357","span":{"begin":1195,"end":1197},"obj":"SO_EXT:wild_type_entity_or_quality"},{"id":"T6358","span":{"begin":1198,"end":1204},"obj":"SO_EXT:0001023"},{"id":"T6359","span":{"begin":1223,"end":1227},"obj":"PR_EXT:000004503"},{"id":"T6360","span":{"begin":1228,"end":1232},"obj":"SO_EXT:sequence_nullness"},{"id":"T6361","span":{"begin":1233,"end":1239},"obj":"SO_EXT:0001023"},{"id":"T6362","span":{"begin":1263,"end":1264},"obj":"GO:0000805"},{"id":"T6363","span":{"begin":1293,"end":1315},"obj":"UBERON:0005292"},{"id":"T6364","span":{"begin":1316,"end":1320},"obj":"SO_EXT:sequence_nullness"},{"id":"T6365","span":{"begin":1337,"end":1341},"obj":"PR_EXT:000004503"},{"id":"T6366","span":{"begin":1342,"end":1349},"obj":"CHEBI_PR_EXT:protein"},{"id":"T6367","span":{"begin":1375,"end":1379},"obj":"PR_EXT:000004503"},{"id":"T6368","span":{"begin":1392,"end":1401},"obj":"UBERON:0000922"},{"id":"T6369","span":{"begin":1417,"end":1423},"obj":"GO_EXT:fatality_or_lethality"},{"id":"T6370","span":{"begin":1427,"end":1431},"obj":"PR_EXT:000004503"},{"id":"T6371","span":{"begin":1432,"end":1436},"obj":"SO_EXT:sequence_nullness"},{"id":"T6372","span":{"begin":1437,"end":1438},"obj":"GO:0000806"},{"id":"T6373","span":{"begin":1439,"end":1444},"obj":"PATO_UBERON_EXT:male_or_bearer_of_maleness"},{"id":"T6374","span":{"begin":1495,"end":1504},"obj":"GO:0071514"},{"id":"T6375","span":{"begin":1544,"end":1548},"obj":"PR_EXT:000004503"},{"id":"T6376","span":{"begin":1549,"end":1551},"obj":"SO_EXT:wild_type_entity_or_quality"},{"id":"T6377","span":{"begin":1552,"end":1558},"obj":"SO_EXT:0001023"},{"id":"T6378","span":{"begin":1571,"end":1580},"obj":"UBERON:0000922"},{"id":"T6379","span":{"begin":1620,"end":1626},"obj":"PATO_UBERON_EXT:female_or_bearer_of_femaleness"},{"id":"T6380","span":{"begin":1627,"end":1634},"obj":"UBERON:0000922"}],"relations":[{"id":"R3856","pred":"_lexicallyChainedTo","subj":"T6337","obj":"T6336"},{"id":"R3857","pred":"_lexicallyChainedTo","subj":"T6338","obj":"T6336"}],"text":"Female mice carrying an Atrx null allele (Atrx WT/null;GATA1-cre +/−) were detected at 9.5 dpc (Table 1) and recovered at birth (unpublished data), although at both time points the number of carrier females was lower than that of wild-type (Atrx WT/WT;GATA1-cre +/−) females, suggesting that a proportion of carrier female embryos died in utero. Surviving adult carrier female mice were not phenotypically normal and exhibited mild behavioural abnormalities, although some could reproduce. For all Atrx WT/null carrier female embryos presented in Table 1, the Atrx WT allele was paternally derived, while the Atrx null allele was maternally derived. In the mouse, X chromosome inactivation is subject to parental imprinting in the trophectoderm and primitive endoderm lineages that give rise to the extraembryonic tissues, resulting in inactivation of the paternal X chromosome (Xp) [18]. In contrast, in tissues of the embryo proper (derived from the inner cell mass of the blastocyst) X-inactivation is random [19]. Thus, in the extraembryonic compartment of Atrx WT/null carrier females, normal imprinted X-inactivation would be expected to result in silencing of the paternally derived Atrx WT allele, leaving only the Atrx null allele on the active maternal X (Xm) and thereby render the extraembryonic tissues null for full-length Atrx protein. However, the absence of Atrx in the extraembryonic compartment is lethal in Atrx null/Y males. This suggested the possibility of an escape from imprinted inactivation of the paternally derived Atrx WT allele in the extraembryonic compartment of a proportion of carrier female embryos."}

2_test

{"project":"2_test","denotations":[{"id":"16628246-1152998-85799757","span":{"begin":884,"end":886},"obj":"1152998"},{"id":"16628246-6185603-85799758","span":{"begin":1013,"end":1015},"obj":"6185603"},{"id":"T777","span":{"begin":884,"end":886},"obj":"1152998"},{"id":"T63330","span":{"begin":1013,"end":1015},"obj":"6185603"}],"text":"Female mice carrying an Atrx null allele (Atrx WT/null;GATA1-cre +/−) were detected at 9.5 dpc (Table 1) and recovered at birth (unpublished data), although at both time points the number of carrier females was lower than that of wild-type (Atrx WT/WT;GATA1-cre +/−) females, suggesting that a proportion of carrier female embryos died in utero. Surviving adult carrier female mice were not phenotypically normal and exhibited mild behavioural abnormalities, although some could reproduce. For all Atrx WT/null carrier female embryos presented in Table 1, the Atrx WT allele was paternally derived, while the Atrx null allele was maternally derived. In the mouse, X chromosome inactivation is subject to parental imprinting in the trophectoderm and primitive endoderm lineages that give rise to the extraembryonic tissues, resulting in inactivation of the paternal X chromosome (Xp) [18]. In contrast, in tissues of the embryo proper (derived from the inner cell mass of the blastocyst) X-inactivation is random [19]. Thus, in the extraembryonic compartment of Atrx WT/null carrier females, normal imprinted X-inactivation would be expected to result in silencing of the paternally derived Atrx WT allele, leaving only the Atrx null allele on the active maternal X (Xm) and thereby render the extraembryonic tissues null for full-length Atrx protein. However, the absence of Atrx in the extraembryonic compartment is lethal in Atrx null/Y males. This suggested the possibility of an escape from imprinted inactivation of the paternally derived Atrx WT allele in the extraembryonic compartment of a proportion of carrier female embryos."}

craft-ca-core-dev

{"project":"craft-ca-core-dev","denotations":[{"id":"T6160","span":{"begin":7,"end":11},"obj":"NCBITaxon:10088"},{"id":"T6161","span":{"begin":24,"end":28},"obj":"PR:000004503"},{"id":"T6162","span":{"begin":34,"end":40},"obj":"SO:0001023"},{"id":"T6163","span":{"begin":42,"end":46},"obj":"PR:000004503"},{"id":"T6164","span":{"begin":55,"end":60},"obj":"PR:000007857"},{"id":"T6165","span":{"begin":122,"end":127},"obj":"GO:0007567"},{"id":"T6166","span":{"begin":241,"end":245},"obj":"PR:000004503"},{"id":"T6167","span":{"begin":252,"end":257},"obj":"PR:000007857"},{"id":"T6168","span":{"begin":323,"end":330},"obj":"UBERON:0000922"},{"id":"T6169","span":{"begin":331,"end":335},"obj":"GO:0016265"},{"id":"T6170","span":{"begin":356,"end":361},"obj":"UBERON:0007023"},{"id":"T6171","span":{"begin":377,"end":381},"obj":"NCBITaxon:10088"},{"id":"T6172","span":{"begin":479,"end":488},"obj":"GO:0000003"},{"id":"T6173","span":{"begin":498,"end":502},"obj":"PR:000004503"},{"id":"T6174","span":{"begin":526,"end":533},"obj":"UBERON:0000922"},{"id":"T6175","span":{"begin":560,"end":564},"obj":"PR:000004503"},{"id":"T6176","span":{"begin":568,"end":574},"obj":"SO:0001023"},{"id":"T6177","span":{"begin":609,"end":613},"obj":"PR:000004503"},{"id":"T6178","span":{"begin":619,"end":625},"obj":"SO:0001023"},{"id":"T6179","span":{"begin":657,"end":662},"obj":"NCBITaxon:10088"},{"id":"T6180","span":{"begin":664,"end":676},"obj":"GO:0000805"},{"id":"T6181","span":{"begin":664,"end":689},"obj":"GO:0009048"},{"id":"T6182","span":{"begin":713,"end":723},"obj":"GO:0071514"},{"id":"T6183","span":{"begin":731,"end":744},"obj":"UBERON:0004345"},{"id":"T6184","span":{"begin":749,"end":767},"obj":"UBERON:0008776"},{"id":"T6185","span":{"begin":799,"end":821},"obj":"UBERON:0005292"},{"id":"T6186","span":{"begin":836,"end":851},"obj":"_FRAGMENT"},{"id":"T6187","span":{"begin":856,"end":877},"obj":"GO:0060817"},{"id":"T6188","span":{"begin":879,"end":881},"obj":"GO:0060817"},{"id":"T6189","span":{"begin":865,"end":877},"obj":"GO:0000805"},{"id":"T6190","span":{"begin":905,"end":912},"obj":"UBERON:0000479"},{"id":"T6191","span":{"begin":920,"end":926},"obj":"UBERON:0000922"},{"id":"T6192","span":{"begin":952,"end":967},"obj":"UBERON:0000087"},{"id":"T6193","span":{"begin":975,"end":985},"obj":"UBERON:0000358"},{"id":"T6194","span":{"begin":987,"end":988},"obj":"GO:0000805"},{"id":"T6195","span":{"begin":987,"end":1001},"obj":"GO:0009048"},{"id":"T6196","span":{"begin":1036,"end":1045},"obj":"UBERON:0000922"},{"id":"T6197","span":{"begin":1061,"end":1065},"obj":"PR:000004503"},{"id":"T6198","span":{"begin":1098,"end":1122},"obj":"GO:0060819"},{"id":"T6199","span":{"begin":1108,"end":1109},"obj":"GO:0000805"},{"id":"T6200","span":{"begin":1154,"end":1163},"obj":"GO:0016458"},{"id":"T6201","span":{"begin":1190,"end":1194},"obj":"PR:000004503"},{"id":"T6202","span":{"begin":1198,"end":1204},"obj":"SO:0001023"},{"id":"T6203","span":{"begin":1223,"end":1227},"obj":"PR:000004503"},{"id":"T6204","span":{"begin":1233,"end":1239},"obj":"SO:0001023"},{"id":"T6205","span":{"begin":1263,"end":1264},"obj":"GO:0000805"},{"id":"T6206","span":{"begin":1293,"end":1315},"obj":"UBERON:0005292"},{"id":"T6207","span":{"begin":1337,"end":1341},"obj":"PR:000004503"},{"id":"T6208","span":{"begin":1375,"end":1379},"obj":"PR:000004503"},{"id":"T6209","span":{"begin":1392,"end":1401},"obj":"UBERON:0000922"},{"id":"T6210","span":{"begin":1427,"end":1431},"obj":"PR:000004503"},{"id":"T6211","span":{"begin":1437,"end":1438},"obj":"GO:0000806"},{"id":"T6212","span":{"begin":1495,"end":1504},"obj":"GO:0071514"},{"id":"T6213","span":{"begin":1544,"end":1548},"obj":"PR:000004503"},{"id":"T6214","span":{"begin":1552,"end":1558},"obj":"SO:0001023"},{"id":"T6215","span":{"begin":1571,"end":1580},"obj":"UBERON:0000922"},{"id":"T6216","span":{"begin":1627,"end":1634},"obj":"UBERON:0000922"}],"relations":[{"id":"R3853","pred":"_lexicallyChainedTo","subj":"T6187","obj":"T6186"},{"id":"R3854","pred":"_lexicallyChainedTo","subj":"T6188","obj":"T6186"}],"text":"Female mice carrying an Atrx null allele (Atrx WT/null;GATA1-cre +/−) were detected at 9.5 dpc (Table 1) and recovered at birth (unpublished data), although at both time points the number of carrier females was lower than that of wild-type (Atrx WT/WT;GATA1-cre +/−) females, suggesting that a proportion of carrier female embryos died in utero. Surviving adult carrier female mice were not phenotypically normal and exhibited mild behavioural abnormalities, although some could reproduce. For all Atrx WT/null carrier female embryos presented in Table 1, the Atrx WT allele was paternally derived, while the Atrx null allele was maternally derived. In the mouse, X chromosome inactivation is subject to parental imprinting in the trophectoderm and primitive endoderm lineages that give rise to the extraembryonic tissues, resulting in inactivation of the paternal X chromosome (Xp) [18]. In contrast, in tissues of the embryo proper (derived from the inner cell mass of the blastocyst) X-inactivation is random [19]. Thus, in the extraembryonic compartment of Atrx WT/null carrier females, normal imprinted X-inactivation would be expected to result in silencing of the paternally derived Atrx WT allele, leaving only the Atrx null allele on the active maternal X (Xm) and thereby render the extraembryonic tissues null for full-length Atrx protein. However, the absence of Atrx in the extraembryonic compartment is lethal in Atrx null/Y males. This suggested the possibility of an escape from imprinted inactivation of the paternally derived Atrx WT allele in the extraembryonic compartment of a proportion of carrier female embryos."}