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PMC:1440874 / 29856-31668 JSONTXT

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Id Subject Object Predicate Lexical cue
T5753 0-2 TO denotes To
T5754 3-14 VB denotes investigate
T5755 520-528 VBN denotes cultured
T5756 15-22 IN denotes whether
T5757 50-60 VBN denotes restricted
T5758 23-26 DT denotes the
T5759 39-45 NN denotes defect
T5760 27-38 NN denotes trophoblast
T5761 46-49 VBD denotes was
T5762 61-63 IN denotes to
T5763 64-67 DT denotes the
T5764 68-78 NN denotes production
T5765 79-81 IN denotes of
T5766 82-91 JJ denotes secondary
T5767 92-96 NNS denotes TGCs
T5768 97-98 -LRB- denotes (
T5769 98-106 VBN denotes produced
T5770 107-109 IN denotes by
T5771 110-117 NN denotes diploid
T5772 118-128 NNS denotes precursors
T5773 129-131 IN denotes in
T5774 132-135 DT denotes the
T5775 150-154 NN denotes cone
T5776 136-149 JJ denotes ectoplacental
T5777 155-158 CC denotes and
T5778 159-166 VBN denotes derived
T5779 167-177 RB denotes originally
T5780 178-182 IN denotes from
T5781 183-186 DT denotes the
T5782 193-206 NN denotes trophectoderm
T5783 187-192 JJ denotes polar
T5784 207-216 VBG denotes overlying
T5785 217-220 DT denotes the
T5786 232-236 NN denotes mass
T5787 221-226 JJ denotes inner
T5788 227-231 NN denotes cell
T5789 237-239 IN denotes of
T5790 240-243 DT denotes the
T5791 244-254 NN denotes blastocyst
T5792 254-255 -RRB- denotes )
T5793 256-258 CC denotes or
T5794 259-263 RB denotes also
T5795 264-272 VBD denotes affected
T5796 273-276 DT denotes the
T5797 277-287 NN denotes production
T5798 288-290 IN denotes of
T5799 291-298 JJ denotes primary
T5800 299-303 NNS denotes TGCs
T5801 304-305 -LRB- denotes (
T5802 305-314 VBG denotes resulting
T5803 315-319 IN denotes from
T5804 320-335 NN denotes differentiation
T5805 336-338 IN denotes of
T5806 339-342 DT denotes the
T5807 349-362 NN denotes trophectoderm
T5808 343-348 JJ denotes mural
T5809 363-365 IN denotes of
T5810 366-369 DT denotes the
T5811 370-380 NN denotes blastocyst
T5812 380-381 -RRB- denotes )
T5813 381-383 , denotes ,
T5814 383-394 NNS denotes blastocysts
T5815 395-396 -LRB- denotes (
T5816 400-403 NN denotes dpc
T5817 396-399 CD denotes 3.5
T5818 403-404 -RRB- denotes )
T5819 405-409 IN denotes from
T5820 410-417 NNS denotes crosses
T5821 418-425 IN denotes between
T5822 426-433 NN denotes Atrx WT
T5823 434-438 NN denotes flox
T5824 433-434 HYPH denotes /
T5825 439-446 NNS denotes females
T5826 447-450 CC denotes and
T5827 451-456 NN denotes GATA1
T5828 457-460 NN denotes Cre
T5829 456-457 HYPH denotes -
T5830 461-471 JJ denotes homozygous
T5831 483-488 NNS denotes males
T5832 472-482 JJ denotes transgenic
T5833 489-490 -LRB- denotes (
T5834 490-497 NN denotes Atrx WT
T5835 498-499 NN denotes Y
T5836 497-498 HYPH denotes /
T5837 499-500 : denotes ;
T5838 500-505 NN denotes GATA1
T5839 506-509 NN denotes Cre
T5840 505-506 HYPH denotes -
T5841 510-511 SYM denotes +
T5842 511-512 HYPH denotes /
T5843 512-513 SYM denotes +
T5844 513-514 -RRB- denotes )
T5845 515-519 VBD denotes were
T5846 529-531 FW denotes in
T5847 532-537 FW denotes vitro
T5848 538-541 IN denotes for
T5849 542-543 CD denotes 5
T5850 544-545 NNS denotes d
T5851 546-548 TO denotes to
T5852 549-556 VB denotes monitor
T5853 557-566 NN denotes outgrowth
T5854 567-569 IN denotes of
T5855 570-573 DT denotes the
T5856 582-593 NN denotes trophoblast
T5857 574-581 JJ denotes primary
T5858 593-594 . denotes .
T5859 594-769 sentence denotes After 5 d, individual blastocyst cultures were scored for the extent of primary trophoblast outgrowth, and the Atrx genotype and sex of the blastocyst were determined by PCR.
T5860 595-600 IN denotes After
T5861 642-648 VBN denotes scored
T5862 601-602 CD denotes 5
T5863 603-604 NNS denotes d
T5864 604-606 , denotes ,
T5865 606-616 JJ denotes individual
T5866 628-636 NNS denotes cultures
T5867 617-627 NN denotes blastocyst
T5868 637-641 VBD denotes were
T5869 649-652 IN denotes for
T5870 653-656 DT denotes the
T5871 657-663 NN denotes extent
T5872 664-666 IN denotes of
T5873 667-674 JJ denotes primary
T5874 687-696 NN denotes outgrowth
T5875 675-686 NN denotes trophoblast
T5876 696-698 , denotes ,
T5877 698-701 CC denotes and
T5878 702-705 DT denotes the
T5879 711-719 NN denotes genotype
T5880 706-710 NN denotes Atrx
T5881 751-761 VBN denotes determined
T5882 720-723 CC denotes and
T5883 724-727 NN denotes sex
T5884 728-730 IN denotes of
T5885 731-734 DT denotes the
T5886 735-745 NN denotes blastocyst
T5887 746-750 VBD denotes were
T5888 762-764 IN denotes by
T5889 765-768 NN denotes PCR
T5890 768-769 . denotes .
T5891 769-942 sentence denotes Most blastocysts hatched from the zona pellucida within 24 h, and trophoblast cells spreading out from the inner cell mass could usually be detected within 48 h of culture.
T5892 770-774 JJS denotes Most
T5893 775-786 NNS denotes blastocysts
T5894 787-794 VBN denotes hatched
T5895 795-799 IN denotes from
T5896 800-803 DT denotes the
T5897 809-818 NN denotes pellucida
T5898 804-808 NN denotes zona
T5899 819-825 IN denotes within
T5900 826-828 CD denotes 24
T5901 829-830 NNS denotes h
T5902 830-832 , denotes ,
T5903 832-835 CC denotes and
T5904 836-847 NN denotes trophoblast
T5905 848-853 NNS denotes cells
T5906 910-918 VBN denotes detected
T5907 854-863 VBG denotes spreading
T5908 864-867 RP denotes out
T5909 868-872 IN denotes from
T5910 873-876 DT denotes the
T5911 888-892 NN denotes mass
T5912 877-882 JJ denotes inner
T5913 883-887 NN denotes cell
T5914 893-898 MD denotes could
T5915 899-906 RB denotes usually
T5916 907-909 VB denotes be
T5917 919-925 IN denotes within
T5918 926-928 CD denotes 48
T5919 929-930 NNS denotes h
T5920 931-933 IN denotes of
T5921 934-941 NN denotes culture
T5922 941-942 . denotes .
T5923 942-1305 sentence denotes No difference was observed in the rate or extent of trophoblast outgrowth over 5 d of culture between Atrxnull blastocysts (Atrx null/Y, n = 6) and blastocysts bearing an Atrx WT allele (Atrx WT/WT, n = 6; Atrx WT/null, n = 6; Atrx WT/Y, n = 6) (examples shown in Figure 7D), suggesting that the defect specifically involves the secondary giant cell compartment.
T5924 943-945 DT denotes No
T5925 946-956 NN denotes difference
T5926 961-969 VBN denotes observed
T5927 957-960 VBD denotes was
T5928 970-972 IN denotes in
T5929 973-976 DT denotes the
T5930 977-981 NN denotes rate
T5931 982-984 CC denotes or
T5932 985-991 NN denotes extent
T5933 992-994 IN denotes of
T5934 995-1006 NN denotes trophoblast
T5935 1007-1016 NN denotes outgrowth
T5936 1017-1021 IN denotes over
T5937 1022-1023 CD denotes 5
T5938 1024-1025 NNS denotes d
T5939 1026-1028 IN denotes of
T5940 1029-1036 NN denotes culture
T5941 1037-1044 IN denotes between
T5942 1045-1053 JJ denotes Atrxnull
T5943 1054-1065 NNS denotes blastocysts
T5944 1066-1067 -LRB- denotes (
T5945 1077-1078 NN denotes Y
T5946 1067-1076 JJ denotes Atrx null
T5947 1076-1077 HYPH denotes /
T5948 1078-1080 , denotes ,
T5949 1080-1081 NN denotes n
T5950 1084-1085 CD denotes 6
T5951 1082-1083 SYM denotes =
T5952 1085-1086 -RRB- denotes )
T5953 1087-1090 CC denotes and
T5954 1091-1102 NNS denotes blastocysts
T5955 1103-1110 VBG denotes bearing
T5956 1111-1113 DT denotes an
T5957 1122-1128 NN denotes allele
T5958 1114-1121 NN denotes Atrx WT
T5959 1129-1130 -LRB- denotes (
T5960 1185-1186 CD denotes 6
T5961 1130-1137 NN denotes Atrx WT
T5962 1138-1140 NN denotes WT
T5963 1137-1138 HYPH denotes /
T5964 1146-1147 CD denotes 6
T5965 1140-1142 , denotes ,
T5966 1142-1143 NN denotes n
T5967 1144-1145 SYM denotes =
T5968 1147-1148 : denotes ;
T5969 1149-1156 NN denotes Atrx WT
T5970 1157-1161 NN denotes null
T5971 1156-1157 HYPH denotes /
T5972 1167-1168 CD denotes 6
T5973 1161-1163 , denotes ,
T5974 1163-1164 NN denotes n
T5975 1165-1166 SYM denotes =
T5976 1168-1169 : denotes ;
T5977 1170-1177 NN denotes Atrx WT
T5978 1178-1179 NN denotes Y
T5979 1177-1178 HYPH denotes /
T5980 1179-1181 , denotes ,
T5981 1181-1182 NN denotes n
T5982 1183-1184 SYM denotes =
T5983 1186-1187 -RRB- denotes )
T5984 1188-1189 -LRB- denotes (
T5985 1198-1203 VBN denotes shown
T5986 1189-1197 NNS denotes examples
T5987 1204-1206 IN denotes in
T5988 1207-1213 NN denotes Figure
T5989 1214-1216 NN denotes 7D
T5990 1216-1217 -RRB- denotes )
T5991 1217-1219 , denotes ,
T5992 1219-1229 VBG denotes suggesting
T5993 1230-1234 IN denotes that
T5994 1259-1267 VBZ denotes involves
T5995 1235-1238 DT denotes the
T5996 1239-1245 NN denotes defect
T5997 1246-1258 RB denotes specifically
T5998 1268-1271 DT denotes the
T5999 1293-1304 NN denotes compartment
T6000 1272-1281 JJ denotes secondary
T6001 1282-1287 JJ denotes giant
T6002 1288-1292 NN denotes cell
T6003 1304-1305 . denotes .
T6004 1305-1421 sentence denotes This is consistent with the observation that Atrxnull conceptuses implant successfully and survive to gastrulation.
T6005 1306-1310 DT denotes This
T6006 1311-1313 VBZ denotes is
T6007 1314-1324 JJ denotes consistent
T6008 1325-1329 IN denotes with
T6009 1330-1333 DT denotes the
T6010 1334-1345 NN denotes observation
T6011 1346-1350 IN denotes that
T6012 1372-1379 VBP denotes implant
T6013 1351-1359 JJ denotes Atrxnull
T6014 1360-1371 NNS denotes conceptuses
T6015 1380-1392 RB denotes successfully
T6016 1393-1396 CC denotes and
T6017 1397-1404 VBP denotes survive
T6018 1405-1407 IN denotes to
T6019 1408-1420 NN denotes gastrulation
T6020 1420-1421 . denotes .
T6021 1421-1567 sentence denotes Taken together, these data suggest that loss of Atrx results in a defect in formation of the secondary trophoblast that is apparent from 7.5 dpc.
T6022 1422-1427 VBN denotes Taken
T6023 1449-1456 VBP denotes suggest
T6024 1428-1436 RB denotes together
T6025 1436-1438 , denotes ,
T6026 1438-1443 DT denotes these
T6027 1444-1448 NNS denotes data
T6028 1457-1461 IN denotes that
T6029 1475-1482 VBZ denotes results
T6030 1462-1466 NN denotes loss
T6031 1467-1469 IN denotes of
T6032 1470-1474 NN denotes Atrx
T6033 1483-1485 IN denotes in
T6034 1486-1487 DT denotes a
T6035 1488-1494 NN denotes defect
T6036 1495-1497 IN denotes in
T6037 1498-1507 NN denotes formation
T6038 1508-1510 IN denotes of
T6039 1511-1514 DT denotes the
T6040 1525-1536 NN denotes trophoblast
T6041 1515-1524 JJ denotes secondary
T6042 1537-1541 WDT denotes that
T6043 1542-1544 VBZ denotes is
T6044 1545-1553 JJ denotes apparent
T6045 1554-1558 IN denotes from
T6046 1559-1562 CD denotes 7.5
T6047 1563-1566 NN denotes dpc
T6048 1566-1567 . denotes .
T6049 1567-1812 sentence denotes Despite initiating normal organisation in the embryo proper, Atrxnull conceptuses exhibit a proliferative defect by 7.5 dpc and die by around 9.5 dpc, probably due to a nutritional deficit resulting from failure to develop a normal trophoblast.
T6050 1568-1575 IN denotes Despite
T6051 1650-1657 VBP denotes exhibit
T6052 1576-1586 VBG denotes initiating
T6053 1587-1593 JJ denotes normal
T6054 1594-1606 NN denotes organisation
T6055 1607-1609 IN denotes in
T6056 1610-1613 DT denotes the
T6057 1614-1620 NN denotes embryo
T6058 1621-1627 JJ denotes proper
T6059 1627-1629 , denotes ,
T6060 1629-1637 JJ denotes Atrxnull
T6061 1638-1649 NNS denotes conceptuses
T6062 1658-1659 DT denotes a
T6063 1674-1680 NN denotes defect
T6064 1660-1673 JJ denotes proliferative
T6065 1681-1683 IN denotes by
T6066 1684-1687 CD denotes 7.5
T6067 1688-1691 NN denotes dpc
T6068 1692-1695 CC denotes and
T6069 1696-1699 VBP denotes die
T6070 1700-1702 IN denotes by
T6071 1703-1709 IN denotes around
T6072 1710-1713 CD denotes 9.5
T6073 1714-1717 NN denotes dpc
T6074 1717-1719 , denotes ,
T6075 1719-1727 RB denotes probably
T6076 1728-1731 IN denotes due
T6077 1732-1734 IN denotes to
T6078 1735-1736 DT denotes a
T6079 1749-1756 NN denotes deficit
T6080 1737-1748 JJ denotes nutritional
T6081 1757-1766 VBG denotes resulting
T6082 1767-1771 IN denotes from
T6083 1772-1779 NN denotes failure
T6084 1780-1782 TO denotes to
T6085 1783-1790 VB denotes develop
T6086 1791-1792 DT denotes a
T6087 1800-1811 NN denotes trophoblast
T6088 1793-1799 JJ denotes normal
T6089 1811-1812 . denotes .
R3529 T5753 T5754 aux To,investigate
R3530 T5754 T5755 advcl investigate,cultured
R3531 T5756 T5757 mark whether,restricted
R3532 T5757 T5754 ccomp restricted,investigate
R3533 T5758 T5759 det the,defect
R3534 T5759 T5757 nsubjpass defect,restricted
R3535 T5760 T5759 compound trophoblast,defect
R3536 T5761 T5757 auxpass was,restricted
R3537 T5762 T5757 prep to,restricted
R3538 T5763 T5764 det the,production
R3539 T5764 T5762 pobj production,to
R3540 T5765 T5764 prep of,production
R3541 T5766 T5767 amod secondary,TGCs
R3542 T5767 T5765 pobj TGCs,of
R3543 T5768 T5767 punct (,TGCs
R3544 T5769 T5767 acl produced,TGCs
R3545 T5770 T5769 agent by,produced
R3546 T5771 T5772 compound diploid,precursors
R3547 T5772 T5770 pobj precursors,by
R3548 T5773 T5769 prep in,produced
R3549 T5774 T5775 det the,cone
R3550 T5775 T5773 pobj cone,in
R3551 T5776 T5775 amod ectoplacental,cone
R3552 T5777 T5769 cc and,produced
R3553 T5778 T5769 conj derived,produced
R3554 T5779 T5778 advmod originally,derived
R3555 T5780 T5778 prep from,derived
R3556 T5781 T5782 det the,trophectoderm
R3557 T5782 T5780 pobj trophectoderm,from
R3558 T5783 T5782 amod polar,trophectoderm
R3559 T5784 T5782 acl overlying,trophectoderm
R3560 T5785 T5786 det the,mass
R3561 T5786 T5784 dobj mass,overlying
R3562 T5787 T5786 amod inner,mass
R3563 T5788 T5786 compound cell,mass
R3564 T5789 T5786 prep of,mass
R3565 T5790 T5791 det the,blastocyst
R3566 T5791 T5789 pobj blastocyst,of
R3567 T5792 T5757 punct ),restricted
R3568 T5793 T5757 cc or,restricted
R3569 T5794 T5795 advmod also,affected
R3570 T5795 T5757 conj affected,restricted
R3571 T5796 T5797 det the,production
R3572 T5797 T5795 dobj production,affected
R3573 T5798 T5797 prep of,production
R3574 T5799 T5800 amod primary,TGCs
R3575 T5800 T5798 pobj TGCs,of
R3576 T5801 T5800 punct (,TGCs
R3577 T5802 T5800 acl resulting,TGCs
R3578 T5803 T5802 prep from,resulting
R3579 T5804 T5803 pobj differentiation,from
R3580 T5805 T5804 prep of,differentiation
R3581 T5806 T5807 det the,trophectoderm
R3582 T5807 T5805 pobj trophectoderm,of
R3583 T5808 T5807 amod mural,trophectoderm
R3584 T5809 T5807 prep of,trophectoderm
R3585 T5810 T5811 det the,blastocyst
R3586 T5811 T5809 pobj blastocyst,of
R3587 T5812 T5755 punct ),cultured
R3588 T5813 T5755 punct ", ",cultured
R3589 T5814 T5755 nsubjpass blastocysts,cultured
R3590 T5815 T5816 punct (,dpc
R3591 T5816 T5814 parataxis dpc,blastocysts
R3592 T5817 T5816 nummod 3.5,dpc
R3593 T5818 T5816 punct ),dpc
R3594 T5819 T5814 prep from,blastocysts
R3595 T5820 T5819 pobj crosses,from
R3596 T5821 T5820 prep between,crosses
R3597 T5822 T5823 compound Atrx WT,flox
R3598 T5823 T5825 compound flox,females
R3599 T5824 T5823 punct /,flox
R3600 T5825 T5821 pobj females,between
R3601 T5826 T5825 cc and,females
R3602 T5827 T5828 compound GATA1,Cre
R3603 T5828 T5830 npadvmod Cre,homozygous
R3604 T5829 T5828 punct -,Cre
R3605 T5830 T5831 amod homozygous,males
R3606 T5831 T5825 conj males,females
R3607 T5832 T5831 amod transgenic,males
R3608 T5833 T5825 punct (,females
R3609 T5834 T5835 compound Atrx WT,Y
R3610 T5835 T5825 appos Y,females
R3611 T5836 T5835 punct /,Y
R3612 T5837 T5835 punct ;,Y
R3613 T5838 T5839 compound GATA1,Cre
R3614 T5839 T5835 appos Cre,Y
R3615 T5840 T5839 punct -,Cre
R3616 T5841 T5839 punct +,Cre
R3617 T5842 T5839 punct /,Cre
R3618 T5843 T5839 punct +,Cre
R3619 T5844 T5755 punct ),cultured
R3620 T5845 T5755 auxpass were,cultured
R3621 T5846 T5847 advmod in,vitro
R3622 T5847 T5755 advmod vitro,cultured
R3623 T5848 T5755 prep for,cultured
R3624 T5849 T5850 nummod 5,d
R3625 T5850 T5848 pobj d,for
R3626 T5851 T5852 aux to,monitor
R3627 T5852 T5755 advcl monitor,cultured
R3628 T5853 T5852 dobj outgrowth,monitor
R3629 T5854 T5853 prep of,outgrowth
R3630 T5855 T5856 det the,trophoblast
R3631 T5856 T5854 pobj trophoblast,of
R3632 T5857 T5856 amod primary,trophoblast
R3633 T5858 T5755 punct .,cultured
R3634 T5860 T5861 prep After,scored
R3635 T5862 T5863 nummod 5,d
R3636 T5863 T5860 pobj d,After
R3637 T5864 T5861 punct ", ",scored
R3638 T5865 T5866 amod individual,cultures
R3639 T5866 T5861 nsubjpass cultures,scored
R3640 T5867 T5866 compound blastocyst,cultures
R3641 T5868 T5861 auxpass were,scored
R3642 T5869 T5861 prep for,scored
R3643 T5870 T5871 det the,extent
R3644 T5871 T5869 pobj extent,for
R3645 T5872 T5871 prep of,extent
R3646 T5873 T5874 amod primary,outgrowth
R3647 T5874 T5872 pobj outgrowth,of
R3648 T5875 T5874 compound trophoblast,outgrowth
R3649 T5876 T5861 punct ", ",scored
R3650 T5877 T5861 cc and,scored
R3651 T5878 T5879 det the,genotype
R3652 T5879 T5881 nsubjpass genotype,determined
R3653 T5880 T5879 compound Atrx,genotype
R3654 T5881 T5861 conj determined,scored
R3655 T5882 T5879 cc and,genotype
R3656 T5883 T5879 conj sex,genotype
R3657 T5884 T5883 prep of,sex
R3658 T5885 T5886 det the,blastocyst
R3659 T5886 T5884 pobj blastocyst,of
R3660 T5887 T5881 auxpass were,determined
R3661 T5888 T5881 prep by,determined
R3662 T5889 T5888 pobj PCR,by
R3663 T5890 T5861 punct .,scored
R3664 T5892 T5893 amod Most,blastocysts
R3665 T5893 T5894 nsubj blastocysts,hatched
R3666 T5895 T5894 prep from,hatched
R3667 T5896 T5897 det the,pellucida
R3668 T5897 T5895 pobj pellucida,from
R3669 T5898 T5897 compound zona,pellucida
R3670 T5899 T5894 prep within,hatched
R3671 T5900 T5901 nummod 24,h
R3672 T5901 T5899 pobj h,within
R3673 T5902 T5894 punct ", ",hatched
R3674 T5903 T5894 cc and,hatched
R3675 T5904 T5905 compound trophoblast,cells
R3676 T5905 T5906 nsubjpass cells,detected
R3677 T5906 T5894 conj detected,hatched
R3678 T5907 T5905 acl spreading,cells
R3679 T5908 T5907 prt out,spreading
R3680 T5909 T5907 prep from,spreading
R3681 T5910 T5911 det the,mass
R3682 T5911 T5909 pobj mass,from
R3683 T5912 T5911 amod inner,mass
R3684 T5913 T5911 compound cell,mass
R3685 T5914 T5906 aux could,detected
R3686 T5915 T5906 advmod usually,detected
R3687 T5916 T5906 auxpass be,detected
R3688 T5917 T5906 prep within,detected
R3689 T5918 T5919 nummod 48,h
R3690 T5919 T5917 pobj h,within
R3691 T5920 T5919 prep of,h
R3692 T5921 T5920 pobj culture,of
R3693 T5922 T5906 punct .,detected
R3694 T5924 T5925 det No,difference
R3695 T5925 T5926 nsubjpass difference,observed
R3696 T5927 T5926 auxpass was,observed
R3697 T5928 T5926 prep in,observed
R3698 T5929 T5930 det the,rate
R3699 T5930 T5928 pobj rate,in
R3700 T5931 T5930 cc or,rate
R3701 T5932 T5930 conj extent,rate
R3702 T5933 T5930 prep of,rate
R3703 T5934 T5935 compound trophoblast,outgrowth
R3704 T5935 T5933 pobj outgrowth,of
R3705 T5936 T5926 prep over,observed
R3706 T5937 T5938 nummod 5,d
R3707 T5938 T5936 pobj d,over
R3708 T5939 T5938 prep of,d
R3709 T5940 T5939 pobj culture,of
R3710 T5941 T5926 prep between,observed
R3711 T5942 T5943 amod Atrxnull,blastocysts
R3712 T5943 T5941 pobj blastocysts,between
R3713 T5944 T5945 punct (,Y
R3714 T5945 T5943 parataxis Y,blastocysts
R3715 T5946 T5945 amod Atrx null,Y
R3716 T5947 T5945 punct /,Y
R3717 T5948 T5945 punct ", ",Y
R3718 T5949 T5950 nsubj n,6
R3719 T5950 T5945 ccomp 6,Y
R3720 T5951 T5950 punct =,6
R3721 T5952 T5945 punct ),Y
R3722 T5953 T5943 cc and,blastocysts
R3723 T5954 T5943 conj blastocysts,blastocysts
R3724 T5955 T5954 acl bearing,blastocysts
R3725 T5956 T5957 det an,allele
R3726 T5957 T5955 dobj allele,bearing
R3727 T5958 T5957 compound Atrx WT,allele
R3728 T5959 T5960 punct (,6
R3729 T5960 T5954 parataxis 6,blastocysts
R3730 T5961 T5962 compound Atrx WT,WT
R3731 T5962 T5964 dep WT,6
R3732 T5963 T5962 punct /,WT
R3733 T5964 T5960 dep 6,6
R3734 T5965 T5964 punct ", ",6
R3735 T5966 T5964 nsubj n,6
R3736 T5967 T5964 punct =,6
R3737 T5968 T5960 punct ;,6
R3738 T5969 T5970 compound Atrx WT,null
R3739 T5970 T5972 dep null,6
R3740 T5971 T5970 punct /,null
R3741 T5972 T5960 dep 6,6
R3742 T5973 T5972 punct ", ",6
R3743 T5974 T5972 nsubj n,6
R3744 T5975 T5972 punct =,6
R3745 T5976 T5960 punct ;,6
R3746 T5977 T5978 compound Atrx WT,Y
R3747 T5978 T5960 dep Y,6
R3748 T5979 T5978 punct /,Y
R3749 T5980 T5960 punct ", ",6
R3750 T5981 T5960 nsubj n,6
R3751 T5982 T5960 punct =,6
R3752 T5983 T5960 punct ),6
R3753 T5984 T5985 punct (,shown
R3754 T5985 T5954 parataxis shown,blastocysts
R3755 T5986 T5985 nsubj examples,shown
R3756 T5987 T5985 prep in,shown
R3757 T5988 T5989 compound Figure,7D
R3758 T5989 T5987 pobj 7D,in
R3759 T5990 T5985 punct ),shown
R3760 T5991 T5926 punct ", ",observed
R3761 T5992 T5926 advcl suggesting,observed
R3762 T5993 T5994 mark that,involves
R3763 T5994 T5992 ccomp involves,suggesting
R3764 T5995 T5996 det the,defect
R3765 T5996 T5994 nsubj defect,involves
R3766 T5997 T5994 advmod specifically,involves
R3767 T5998 T5999 det the,compartment
R3768 T5999 T5994 dobj compartment,involves
R3769 T6000 T5999 amod secondary,compartment
R3770 T6001 T5999 amod giant,compartment
R3771 T6002 T5999 compound cell,compartment
R3772 T6003 T5926 punct .,observed
R3773 T6005 T6006 nsubj This,is
R3774 T6007 T6006 acomp consistent,is
R3775 T6008 T6007 prep with,consistent
R3776 T6009 T6010 det the,observation
R3777 T6010 T6008 pobj observation,with
R3778 T6011 T6012 mark that,implant
R3779 T6012 T6010 acl implant,observation
R3780 T6013 T6014 amod Atrxnull,conceptuses
R3781 T6014 T6012 nsubj conceptuses,implant
R3782 T6015 T6012 advmod successfully,implant
R3783 T6016 T6012 cc and,implant
R3784 T6017 T6012 conj survive,implant
R3785 T6018 T6017 prep to,survive
R3786 T6019 T6018 pobj gastrulation,to
R3787 T6020 T6006 punct .,is
R3788 T6022 T6023 advcl Taken,suggest
R3789 T6024 T6022 advmod together,Taken
R3790 T6025 T6023 punct ", ",suggest
R3791 T6026 T6027 det these,data
R3792 T6027 T6023 nsubj data,suggest
R3793 T6028 T6029 mark that,results
R3794 T6029 T6023 ccomp results,suggest
R3795 T6030 T6029 nsubj loss,results
R3796 T6031 T6030 prep of,loss
R3797 T6032 T6031 pobj Atrx,of
R3798 T6033 T6029 prep in,results
R3799 T6034 T6035 det a,defect
R3800 T6035 T6033 pobj defect,in
R3801 T6036 T6035 prep in,defect
R3802 T6037 T6036 pobj formation,in
R3803 T6038 T6037 prep of,formation
R3804 T6039 T6040 det the,trophoblast
R3805 T6040 T6038 pobj trophoblast,of
R3806 T6041 T6040 amod secondary,trophoblast
R3807 T6042 T6043 dep that,is
R3808 T6043 T6035 relcl is,defect
R3809 T6044 T6043 acomp apparent,is
R3810 T6045 T6043 prep from,is
R3811 T6046 T6047 nummod 7.5,dpc
R3812 T6047 T6045 pobj dpc,from
R3813 T6048 T6023 punct .,suggest
R3814 T6050 T6051 prep Despite,exhibit
R3815 T6052 T6050 pcomp initiating,Despite
R3816 T6053 T6054 amod normal,organisation
R3817 T6054 T6052 dobj organisation,initiating
R3818 T6055 T6052 prep in,initiating
R3819 T6056 T6057 det the,embryo
R3820 T6057 T6055 pobj embryo,in
R3821 T6058 T6057 amod proper,embryo
R3822 T6059 T6051 punct ", ",exhibit
R3823 T6060 T6061 amod Atrxnull,conceptuses
R3824 T6061 T6051 nsubj conceptuses,exhibit
R3825 T6062 T6063 det a,defect
R3826 T6063 T6051 dobj defect,exhibit
R3827 T6064 T6063 amod proliferative,defect
R3828 T6065 T6051 prep by,exhibit
R3829 T6066 T6067 nummod 7.5,dpc
R3830 T6067 T6065 pobj dpc,by
R3831 T6068 T6051 cc and,exhibit
R3832 T6069 T6051 conj die,exhibit
R3833 T6070 T6069 prep by,die
R3834 T6071 T6072 quantmod around,9.5
R3835 T6072 T6073 nummod 9.5,dpc
R3836 T6073 T6070 pobj dpc,by
R3837 T6074 T6051 punct ", ",exhibit
R3838 T6075 T6076 advmod probably,due
R3839 T6076 T6051 prep due,exhibit
R3840 T6077 T6076 pcomp to,due
R3841 T6078 T6079 det a,deficit
R3842 T6079 T6076 pobj deficit,due
R3843 T6080 T6079 amod nutritional,deficit
R3844 T6081 T6079 acl resulting,deficit
R3845 T6082 T6081 prep from,resulting
R3846 T6083 T6082 pobj failure,from
R3847 T6084 T6085 aux to,develop
R3848 T6085 T6083 acl develop,failure
R3849 T6086 T6087 det a,trophoblast
R3850 T6087 T6085 dobj trophoblast,develop
R3851 T6088 T6087 amod normal,trophoblast
R3852 T6089 T6051 punct .,exhibit

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T5425 27-38 UBERON:0000088 denotes trophoblast
T5426 82-96 CL:0002498 denotes secondary TGCs
T5427 136-154 UBERON:0004364 denotes ectoplacental cone
T5428 187-206 UBERON:0006280 denotes polar trophectoderm
T5429 221-236 UBERON:0000087 denotes inner cell mass
T5430 227-231 CL_GO_EXT:cell denotes cell
T5431 244-254 UBERON:0000358 denotes blastocyst
T5432 291-303 CL:0002497 denotes primary TGCs
T5433 320-335 GO_RO_EXT:developmental_differentiation_process denotes differentiation
T5434 343-362 UBERON:0006265 denotes mural trophectoderm
T5435 370-380 UBERON:0000358 denotes blastocyst
T5436 383-394 UBERON:0000358 denotes blastocysts
T5437 426-430 PR_EXT:000004503 denotes Atrx
T5438 431-433 SO_EXT:wild_type_entity_or_quality denotes WT
T5439 434-438 SO:0000359 denotes flox
T5440 439-446 PATO_UBERON_EXT:female_or_bearer_of_femaleness denotes females
T5441 451-456 PR_EXT:000007857 denotes GATA1
T5442 472-482 SO_EXT:transgenic_entity denotes transgenic
T5443 483-488 PATO_UBERON_EXT:male_or_bearer_of_maleness denotes males
T5444 490-494 PR_EXT:000004503 denotes Atrx
T5445 495-497 SO_EXT:wild_type_entity_or_quality denotes WT
T5446 500-505 PR_EXT:000007857 denotes GATA1
T5447 510-511 SO_EXT:normal_or_wild_type_or_present denotes +
T5448 512-513 SO_EXT:normal_or_wild_type_or_present denotes +
T5449 582-593 UBERON:0000088 denotes trophoblast
T5450 617-627 UBERON:0000358 denotes blastocyst
T5451 675-686 UBERON:0000088 denotes trophoblast
T5452 706-710 PR_EXT:000004503 denotes Atrx
T5453 711-719 SO_EXT:genotype_or_entity_with_genotype denotes genotype
T5454 735-745 UBERON:0000358 denotes blastocyst
T5455 775-786 UBERON:0000358 denotes blastocysts
T5456 804-818 UBERON:0000086 denotes zona pellucida
T5457 836-847 UBERON:0000088 denotes trophoblast
T5458 836-853 CL:0000351 denotes trophoblast cells
T5459 848-853 CL_GO_EXT:cell denotes cells
T5460 877-892 UBERON:0000087 denotes inner cell mass
T5461 883-887 CL_GO_EXT:cell denotes cell
T5462 995-1006 UBERON:0000088 denotes trophoblast
T5463 1045-1049 PR_EXT:000004503 denotes Atrx
T5464 1049-1053 SO_EXT:sequence_nullness denotes null
T5465 1054-1065 UBERON:0000358 denotes blastocysts
T5466 1067-1071 PR_EXT:000004503 denotes Atrx
T5467 1072-1076 SO_EXT:sequence_nullness denotes null
T5468 1091-1102 UBERON:0000358 denotes blastocysts
T5469 1114-1118 PR_EXT:000004503 denotes Atrx
T5470 1119-1121 SO_EXT:wild_type_entity_or_quality denotes WT
T5471 1122-1128 SO_EXT:0001023 denotes allele
T5472 1130-1134 PR_EXT:000004503 denotes Atrx
T5473 1135-1137 SO_EXT:wild_type_entity_or_quality denotes WT
T5474 1138-1140 SO_EXT:wild_type_entity_or_quality denotes WT
T5475 1149-1153 PR_EXT:000004503 denotes Atrx
T5476 1154-1156 SO_EXT:wild_type_entity_or_quality denotes WT
T5477 1157-1161 SO_EXT:sequence_nullness denotes null
T5478 1170-1174 PR_EXT:000004503 denotes Atrx
T5479 1175-1177 SO_EXT:wild_type_entity_or_quality denotes WT
T5480 1272-1292 CL:0002498 denotes secondary giant cell
T5481 1288-1292 CL_GO_EXT:cell denotes cell
T5482 1351-1355 PR_EXT:000004503 denotes Atrx
T5483 1355-1359 SO_EXT:sequence_nullness denotes null
T5484 1360-1371 UBERON:0004716 denotes conceptuses
T5485 1372-1379 GO:0007566 denotes implant
T5486 1408-1420 GO:0007369 denotes gastrulation
T5487 1470-1474 PR_EXT:000004503 denotes Atrx
T5488 1525-1536 UBERON:0000088 denotes trophoblast
T5489 1614-1620 UBERON:0000922 denotes embryo
T5490 1633-1637 SO_EXT:sequence_nullness denotes null
T5491 1638-1649 UBERON:0004716 denotes conceptuses
T5492 1660-1673 GO_PATO_EXT:cell_proliferation_or_proliferativity denotes proliferative
T5493 1696-1699 GO:0016265 denotes die
T5494 1800-1811 UBERON:0000088 denotes trophoblast

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T5325 500-505 PR:000007857 denotes GATA1
T5311 27-38 UBERON:0000088 denotes trophoblast
T5312 82-96 CL:0002498 denotes secondary TGCs
T5313 136-154 UBERON:0004364 denotes ectoplacental cone
T5314 187-206 UBERON:0006280 denotes polar trophectoderm
T5315 221-236 UBERON:0000087 denotes inner cell mass
T5316 244-254 UBERON:0000358 denotes blastocyst
T5317 291-303 CL:0002497 denotes primary TGCs
T5318 343-362 UBERON:0006265 denotes mural trophectoderm
T5319 370-380 UBERON:0000358 denotes blastocyst
T5320 383-394 UBERON:0000358 denotes blastocysts
T5321 426-430 PR:000004503 denotes Atrx
T5322 434-438 SO:0000359 denotes flox
T5323 451-456 PR:000007857 denotes GATA1
T5324 490-494 PR:000004503 denotes Atrx
T5326 582-593 UBERON:0000088 denotes trophoblast
T5327 617-627 UBERON:0000358 denotes blastocyst
T5328 675-686 UBERON:0000088 denotes trophoblast
T5329 706-710 PR:000004503 denotes Atrx
T5330 735-745 UBERON:0000358 denotes blastocyst
T5331 775-786 UBERON:0000358 denotes blastocysts
T5332 804-818 UBERON:0000086 denotes zona pellucida
T5333 836-847 UBERON:0000088 denotes trophoblast
T5334 836-853 CL:0000351 denotes trophoblast cells
T5335 877-892 UBERON:0000087 denotes inner cell mass
T5336 995-1006 UBERON:0000088 denotes trophoblast
T5337 1045-1049 PR:000004503 denotes Atrx
T5338 1054-1065 UBERON:0000358 denotes blastocysts
T5339 1067-1071 PR:000004503 denotes Atrx
T5340 1091-1102 UBERON:0000358 denotes blastocysts
T5341 1114-1118 PR:000004503 denotes Atrx
T5342 1122-1128 SO:0001023 denotes allele
T5343 1130-1134 PR:000004503 denotes Atrx
T5344 1149-1153 PR:000004503 denotes Atrx
T5345 1170-1174 PR:000004503 denotes Atrx
T5346 1272-1292 CL:0002498 denotes secondary giant cell
T5347 1351-1355 PR:000004503 denotes Atrx
T5348 1360-1371 UBERON:0004716 denotes conceptuses
T5349 1372-1379 GO:0007566 denotes implant
T5350 1408-1420 GO:0007369 denotes gastrulation
T5351 1470-1474 PR:000004503 denotes Atrx
T5352 1525-1536 UBERON:0000088 denotes trophoblast
T5353 1614-1620 UBERON:0000922 denotes embryo
T5354 1638-1649 UBERON:0004716 denotes conceptuses
T5355 1696-1699 GO:0016265 denotes die
T5356 1800-1811 UBERON:0000088 denotes trophoblast