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PMC:1440874 / 17787-19276 JSONTXT

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Id Subject Object Predicate Lexical cue
T3964 0-2 TO denotes To
T3965 3-14 VB denotes investigate
T3966 83-94 VBD denotes established
T3967 15-18 DT denotes the
T3968 19-23 NN denotes role
T3969 24-26 IN denotes of
T3970 27-30 DT denotes the
T3971 36-43 NN denotes protein
T3972 31-35 NN denotes Atrx
T3973 44-50 IN denotes during
T3974 51-56 NN denotes mouse
T3975 57-68 NN denotes development
T3976 68-70 , denotes ,
T3977 70-72 PRP denotes we
T3978 73-82 RB denotes initially
T3979 95-100 NNS denotes lines
T3980 101-103 IN denotes of
T3981 104-108 NNS denotes mice
T3982 109-116 VBG denotes bearing
T3983 117-120 DT denotes the
T3984 131-137 NN denotes allele
T3985 121-130 NN denotes Atrx flox
T3986 137-138 . denotes .
T3987 138-337 sentence denotes Two independently targeted Atrx flox ES cell clones with normal male karyotype were injected into C57BL/6 blastocysts to produce chimaeric mice, which were then used to obtain germline transmission.
T3988 139-142 CD denotes Two
T3989 184-190 NNS denotes clones
T3990 143-156 RB denotes independently
T3991 157-165 VBN denotes targeted
T3992 166-175 NN denotes Atrx flox
T3993 176-178 NN denotes ES
T3994 179-183 NN denotes cell
T3995 223-231 VBN denotes injected
T3996 191-195 IN denotes with
T3997 196-202 JJ denotes normal
T3998 208-217 NN denotes karyotype
T3999 203-207 JJ denotes male
T4000 218-222 VBD denotes were
T4001 232-236 IN denotes into
T4002 237-242 NN denotes C57BL
T4003 245-256 NNS denotes blastocysts
T4004 242-243 HYPH denotes /
T4005 243-244 CD denotes 6
T4006 257-259 TO denotes to
T4007 260-267 VB denotes produce
T4008 268-277 JJ denotes chimaeric
T4009 278-282 NNS denotes mice
T4010 282-284 , denotes ,
T4011 284-289 WDT denotes which
T4012 300-304 VBN denotes used
T4013 290-294 VBD denotes were
T4014 295-299 RB denotes then
T4015 305-307 TO denotes to
T4016 308-314 VB denotes obtain
T4017 315-323 NN denotes germline
T4018 324-336 NN denotes transmission
T4019 336-337 . denotes .
T4020 337-522 sentence denotes Intercrosses between males hemizygous (Atrx flox/Y) and females heterozygous (Atrx WT/flox) for the floxed allele were also carried out to generate homozygous females (Atrx flox/flox).
T4021 338-350 NNS denotes Intercrosses
T4022 462-469 VBN denotes carried
T4023 351-358 IN denotes between
T4024 359-364 NNS denotes males
T4025 365-375 JJ denotes hemizygous
T4026 376-377 -LRB- denotes (
T4027 387-388 NN denotes Y
T4028 377-386 NN denotes Atrx flox
T4029 386-387 HYPH denotes /
T4030 388-389 -RRB- denotes )
T4031 390-393 CC denotes and
T4032 394-401 NNS denotes females
T4033 402-414 JJ denotes heterozygous
T4034 415-416 -LRB- denotes (
T4035 424-428 NN denotes flox
T4036 416-423 NN denotes Atrx WT
T4037 423-424 HYPH denotes /
T4038 428-429 -RRB- denotes )
T4039 430-433 IN denotes for
T4040 434-437 DT denotes the
T4041 445-451 NN denotes allele
T4042 438-444 VBN denotes floxed
T4043 452-456 VBD denotes were
T4044 457-461 RB denotes also
T4045 470-473 RP denotes out
T4046 474-476 TO denotes to
T4047 477-485 VB denotes generate
T4048 486-496 JJ denotes homozygous
T4049 497-504 NNS denotes females
T4050 505-506 -LRB- denotes (
T4051 516-520 NN denotes flox
T4052 506-515 NN denotes Atrx flox
T4053 515-516 HYPH denotes /
T4054 520-521 -RRB- denotes )
T4055 521-522 . denotes .
T4056 522-729 sentence denotes Males hemizygous and females heterozygous or homozygous for the Atrx flox allele were viable, appeared healthy, and bred normally, suggesting that, as expected, the Atrx flox allele was functionally normal.
T4057 523-528 NNS denotes Males
T4058 604-608 VBD denotes were
T4059 529-539 JJ denotes hemizygous
T4060 540-543 CC denotes and
T4061 544-551 NNS denotes females
T4062 552-564 JJ denotes heterozygous
T4063 565-567 CC denotes or
T4064 568-578 JJ denotes homozygous
T4065 579-582 IN denotes for
T4066 583-586 DT denotes the
T4067 597-603 NN denotes allele
T4068 587-596 NN denotes Atrx flox
T4069 609-615 JJ denotes viable
T4070 615-617 , denotes ,
T4071 617-625 VBD denotes appeared
T4072 626-633 JJ denotes healthy
T4073 633-635 , denotes ,
T4074 635-638 CC denotes and
T4075 639-643 VBD denotes bred
T4076 644-652 RB denotes normally
T4077 652-654 , denotes ,
T4078 654-664 VBG denotes suggesting
T4079 665-669 IN denotes that
T4080 705-708 VBD denotes was
T4081 669-671 , denotes ,
T4082 671-673 IN denotes as
T4083 674-682 VBN denotes expected
T4084 682-684 , denotes ,
T4085 684-687 DT denotes the
T4086 698-704 NN denotes allele
T4087 688-697 NN denotes Atrx flox
T4088 709-721 RB denotes functionally
T4089 722-728 JJ denotes normal
T4090 728-729 . denotes .
T4091 729-980 sentence denotes To generate Atrxnull mice by Cre-mediated recombination, the Atrx flox mice were crossed with mice harboring a transgene in which the Cre recombinase is expressed under the control of the regulatory elements of the mouse GATA-1 gene (GATA1-cre) [14].
T4092 730-732 TO denotes To
T4093 733-741 VB denotes generate
T4094 811-818 VBN denotes crossed
T4095 742-750 JJ denotes Atrxnull
T4096 751-755 NNS denotes mice
T4097 756-758 IN denotes by
T4098 759-762 NN denotes Cre
T4099 763-771 VBN denotes mediated
T4100 762-763 HYPH denotes -
T4101 772-785 NN denotes recombination
T4102 785-787 , denotes ,
T4103 787-790 DT denotes the
T4104 801-805 NNS denotes mice
T4105 791-800 NN denotes Atrx flox
T4106 806-810 VBD denotes were
T4107 819-823 IN denotes with
T4108 824-828 NNS denotes mice
T4109 829-838 VBG denotes harboring
T4110 839-840 DT denotes a
T4111 841-850 NN denotes transgene
T4112 851-853 IN denotes in
T4113 883-892 VBN denotes expressed
T4114 854-859 WDT denotes which
T4115 860-863 DT denotes the
T4116 868-879 NN denotes recombinase
T4117 864-867 NN denotes Cre
T4118 880-882 VBZ denotes is
T4119 893-898 IN denotes under
T4120 899-902 DT denotes the
T4121 903-910 NN denotes control
T4122 911-913 IN denotes of
T4123 914-917 DT denotes the
T4124 929-937 NNS denotes elements
T4125 918-928 JJ denotes regulatory
T4126 938-940 IN denotes of
T4127 941-944 DT denotes the
T4128 958-962 NN denotes gene
T4129 945-950 NN denotes mouse
T4130 951-955 NN denotes GATA
T4131 955-956 HYPH denotes -
T4132 956-957 CD denotes 1
T4133 963-964 -LRB- denotes (
T4134 964-969 NN denotes GATA1
T4135 970-973 NN denotes cre
T4136 969-970 HYPH denotes -
T4137 973-974 -RRB- denotes )
T4138 975-976 -LRB- denotes [
T4139 976-978 CD denotes 14
T4140 978-979 -RRB- denotes ]
T4141 979-980 . denotes .
T4142 980-1084 sentence denotes Widespread expression of the GATA1-cre transgene has been demonstrated during early embryogenesis [14].
T4143 981-991 JJ denotes Widespread
T4144 992-1002 NN denotes expression
T4145 1039-1051 VBN denotes demonstrated
T4146 1003-1005 IN denotes of
T4147 1006-1009 DT denotes the
T4148 1020-1029 NN denotes transgene
T4149 1010-1015 NN denotes GATA1
T4150 1016-1019 NN denotes cre
T4151 1015-1016 HYPH denotes -
T4152 1030-1033 VBZ denotes has
T4153 1034-1038 VBN denotes been
T4154 1052-1058 IN denotes during
T4155 1059-1064 JJ denotes early
T4156 1065-1078 NN denotes embryogenesis
T4157 1079-1080 -LRB- denotes [
T4158 1080-1082 CD denotes 14
T4159 1082-1083 -RRB- denotes ]
T4160 1083-1084 . denotes .
T4161 1084-1348 sentence denotes We more accurately defined the onset of GATA1-cre expression using a ROSA26 reporter strain, in which a β-galactosidase/neor fusion reporter gene is expressed only after Cre-mediated excision of loxP-flanked transcription and translation termination signals [14].
T4162 1085-1087 PRP denotes We
T4163 1104-1111 VBN denotes defined
T4164 1088-1092 RBR denotes more
T4165 1093-1103 RB denotes accurately
T4166 1112-1115 DT denotes the
T4167 1116-1121 NN denotes onset
T4168 1122-1124 IN denotes of
T4169 1125-1130 NN denotes GATA1
T4170 1131-1134 NN denotes cre
T4171 1130-1131 HYPH denotes -
T4172 1135-1145 NN denotes expression
T4173 1146-1151 VBG denotes using
T4174 1152-1153 DT denotes a
T4175 1170-1176 NN denotes strain
T4176 1154-1160 NN denotes ROSA26
T4177 1161-1169 NN denotes reporter
T4178 1176-1178 , denotes ,
T4179 1178-1180 IN denotes in
T4180 1234-1243 VBN denotes expressed
T4181 1181-1186 WDT denotes which
T4182 1187-1188 DT denotes a
T4183 1226-1230 NN denotes gene
T4184 1189-1190 NN denotes β
T4185 1191-1204 NN denotes galactosidase
T4186 1190-1191 HYPH denotes -
T4187 1210-1216 NN denotes fusion
T4188 1204-1205 HYPH denotes /
T4189 1205-1209 NN denotes neor
T4190 1217-1225 NN denotes reporter
T4191 1231-1233 VBZ denotes is
T4192 1244-1248 RB denotes only
T4193 1249-1254 IN denotes after
T4194 1255-1258 NN denotes Cre
T4195 1259-1267 VBN denotes mediated
T4196 1258-1259 HYPH denotes -
T4197 1268-1276 NN denotes excision
T4198 1277-1279 IN denotes of
T4199 1280-1284 NN denotes loxP
T4200 1285-1292 VBN denotes flanked
T4201 1284-1285 HYPH denotes -
T4202 1293-1306 NN denotes transcription
T4203 1307-1310 CC denotes and
T4204 1311-1322 NN denotes translation
T4205 1323-1334 NN denotes termination
T4206 1335-1342 NNS denotes signals
T4207 1343-1344 -LRB- denotes [
T4208 1344-1346 CD denotes 14
T4209 1346-1347 -RRB- denotes ]
T4210 1347-1348 . denotes .
T4211 1348-1489 sentence denotes We found that the GATA1-cre transgene was already active at the 16-cell morula stage of development (0.5 days postcoitus [dpc]) (Figure 4A).
T4212 1349-1351 PRP denotes We
T4213 1352-1357 VBD denotes found
T4214 1358-1362 IN denotes that
T4215 1387-1390 VBD denotes was
T4216 1363-1366 DT denotes the
T4217 1377-1386 NN denotes transgene
T4218 1367-1372 NN denotes GATA1
T4219 1373-1376 NN denotes cre
T4220 1372-1373 HYPH denotes -
T4221 1391-1398 RB denotes already
T4222 1399-1405 JJ denotes active
T4223 1406-1408 IN denotes at
T4224 1409-1412 DT denotes the
T4225 1428-1433 NN denotes stage
T4226 1413-1415 CD denotes 16
T4227 1416-1420 NN denotes cell
T4228 1415-1416 HYPH denotes -
T4229 1421-1427 NN denotes morula
T4230 1434-1436 IN denotes of
T4231 1437-1448 NN denotes development
T4232 1449-1450 -LRB- denotes (
T4233 1450-1453 CD denotes 0.5
T4234 1454-1458 NNS denotes days
T4235 1459-1469 RB denotes postcoitus
T4236 1470-1471 -LRB- denotes [
T4237 1471-1474 NN denotes dpc
T4238 1474-1475 -RRB- denotes ]
T4239 1475-1476 -RRB- denotes )
T4240 1477-1478 -LRB- denotes (
T4241 1485-1487 NN denotes 4A
T4242 1478-1484 NN denotes Figure
T4243 1487-1488 -RRB- denotes )
T4244 1488-1489 . denotes .
R2111 T3964 T3965 aux To,investigate
R2112 T3965 T3966 advcl investigate,established
R2113 T3967 T3968 det the,role
R2114 T3968 T3965 dobj role,investigate
R2115 T3969 T3968 prep of,role
R2116 T3970 T3971 det the,protein
R2117 T3971 T3969 pobj protein,of
R2118 T3972 T3971 compound Atrx,protein
R2119 T3973 T3968 prep during,role
R2120 T3974 T3975 compound mouse,development
R2121 T3975 T3973 pobj development,during
R2122 T3976 T3966 punct ", ",established
R2123 T3977 T3966 nsubj we,established
R2124 T3978 T3966 advmod initially,established
R2125 T3979 T3966 dobj lines,established
R2126 T3980 T3979 prep of,lines
R2127 T3981 T3980 pobj mice,of
R2128 T3982 T3979 acl bearing,lines
R2129 T3983 T3984 det the,allele
R2130 T3984 T3982 dobj allele,bearing
R2131 T3985 T3984 compound Atrx flox,allele
R2132 T3986 T3966 punct .,established
R2133 T3988 T3989 nummod Two,clones
R2134 T3989 T3995 nsubjpass clones,injected
R2135 T3990 T3991 advmod independently,targeted
R2136 T3991 T3989 amod targeted,clones
R2137 T3992 T3989 compound Atrx flox,clones
R2138 T3993 T3994 compound ES,cell
R2139 T3994 T3989 compound cell,clones
R2140 T3996 T3989 prep with,clones
R2141 T3997 T3998 amod normal,karyotype
R2142 T3998 T3996 pobj karyotype,with
R2143 T3999 T3998 amod male,karyotype
R2144 T4000 T3995 auxpass were,injected
R2145 T4001 T3995 prep into,injected
R2146 T4002 T4003 nmod C57BL,blastocysts
R2147 T4003 T4001 pobj blastocysts,into
R2148 T4004 T4002 punct /,C57BL
R2149 T4005 T4002 nummod 6,C57BL
R2150 T4006 T4007 aux to,produce
R2151 T4007 T3995 advcl produce,injected
R2152 T4008 T4009 amod chimaeric,mice
R2153 T4009 T4007 dobj mice,produce
R2154 T4010 T4009 punct ", ",mice
R2155 T4011 T4012 dep which,used
R2156 T4012 T4009 relcl used,mice
R2157 T4013 T4012 auxpass were,used
R2158 T4014 T4012 advmod then,used
R2159 T4015 T4016 aux to,obtain
R2160 T4016 T4012 advcl obtain,used
R2161 T4017 T4018 compound germline,transmission
R2162 T4018 T4016 dobj transmission,obtain
R2163 T4019 T3995 punct .,injected
R2164 T4021 T4022 nsubjpass Intercrosses,carried
R2165 T4023 T4021 prep between,Intercrosses
R2166 T4024 T4023 pobj males,between
R2167 T4025 T4024 amod hemizygous,males
R2168 T4026 T4027 punct (,Y
R2169 T4027 T4025 parataxis Y,hemizygous
R2170 T4028 T4027 compound Atrx flox,Y
R2171 T4029 T4027 punct /,Y
R2172 T4030 T4027 punct ),Y
R2173 T4031 T4024 cc and,males
R2174 T4032 T4024 conj females,males
R2175 T4033 T4032 amod heterozygous,females
R2176 T4034 T4035 punct (,flox
R2177 T4035 T4033 parataxis flox,heterozygous
R2178 T4036 T4035 compound Atrx WT,flox
R2179 T4037 T4035 punct /,flox
R2180 T4038 T4035 punct ),flox
R2181 T4039 T4032 prep for,females
R2182 T4040 T4041 det the,allele
R2183 T4041 T4039 pobj allele,for
R2184 T4042 T4041 amod floxed,allele
R2185 T4043 T4022 auxpass were,carried
R2186 T4044 T4022 advmod also,carried
R2187 T4045 T4022 prt out,carried
R2188 T4046 T4047 aux to,generate
R2189 T4047 T4022 advcl generate,carried
R2190 T4048 T4049 amod homozygous,females
R2191 T4049 T4047 dobj females,generate
R2192 T4050 T4051 punct (,flox
R2193 T4051 T4049 parataxis flox,females
R2194 T4052 T4051 compound Atrx flox,flox
R2195 T4053 T4051 punct /,flox
R2196 T4054 T4051 punct ),flox
R2197 T4055 T4022 punct .,carried
R2198 T4057 T4058 nsubj Males,were
R2199 T4059 T4057 amod hemizygous,Males
R2200 T4060 T4057 cc and,Males
R2201 T4061 T4057 conj females,Males
R2202 T4062 T4061 amod heterozygous,females
R2203 T4063 T4062 cc or,heterozygous
R2204 T4064 T4062 conj homozygous,heterozygous
R2205 T4065 T4061 prep for,females
R2206 T4066 T4067 det the,allele
R2207 T4067 T4065 pobj allele,for
R2208 T4068 T4067 compound Atrx flox,allele
R2209 T4069 T4058 acomp viable,were
R2210 T4070 T4058 punct ", ",were
R2211 T4071 T4058 conj appeared,were
R2212 T4072 T4071 oprd healthy,appeared
R2213 T4073 T4071 punct ", ",appeared
R2214 T4074 T4071 cc and,appeared
R2215 T4075 T4071 conj bred,appeared
R2216 T4076 T4075 advmod normally,bred
R2217 T4077 T4058 punct ", ",were
R2218 T4078 T4058 advcl suggesting,were
R2219 T4079 T4080 mark that,was
R2220 T4080 T4078 ccomp was,suggesting
R2221 T4081 T4080 punct ", ",was
R2222 T4082 T4083 mark as,expected
R2223 T4083 T4080 advcl expected,was
R2224 T4084 T4080 punct ", ",was
R2225 T4085 T4086 det the,allele
R2226 T4086 T4080 nsubj allele,was
R2227 T4087 T4086 compound Atrx flox,allele
R2228 T4088 T4089 advmod functionally,normal
R2229 T4089 T4080 acomp normal,was
R2230 T4090 T4058 punct .,were
R2231 T4092 T4093 aux To,generate
R2232 T4093 T4094 advcl generate,crossed
R2233 T4095 T4096 amod Atrxnull,mice
R2234 T4096 T4093 dobj mice,generate
R2235 T4097 T4093 prep by,generate
R2236 T4098 T4099 npadvmod Cre,mediated
R2237 T4099 T4101 amod mediated,recombination
R2238 T4100 T4099 punct -,mediated
R2239 T4101 T4097 pobj recombination,by
R2240 T4102 T4094 punct ", ",crossed
R2241 T4103 T4104 det the,mice
R2242 T4104 T4094 nsubjpass mice,crossed
R2243 T4105 T4104 compound Atrx flox,mice
R2244 T4106 T4094 auxpass were,crossed
R2245 T4107 T4094 prep with,crossed
R2246 T4108 T4107 pobj mice,with
R2247 T4109 T4108 acl harboring,mice
R2248 T4110 T4111 det a,transgene
R2249 T4111 T4109 dobj transgene,harboring
R2250 T4112 T4113 prep in,expressed
R2251 T4113 T4111 relcl expressed,transgene
R2252 T4114 T4112 pobj which,in
R2253 T4115 T4116 det the,recombinase
R2254 T4116 T4113 nsubjpass recombinase,expressed
R2255 T4117 T4116 compound Cre,recombinase
R2256 T4118 T4113 auxpass is,expressed
R2257 T4119 T4113 prep under,expressed
R2258 T4120 T4121 det the,control
R2259 T4121 T4119 pobj control,under
R2260 T4122 T4121 prep of,control
R2261 T4123 T4124 det the,elements
R2262 T4124 T4122 pobj elements,of
R2263 T4125 T4124 amod regulatory,elements
R2264 T4126 T4124 prep of,elements
R2265 T4127 T4128 det the,gene
R2266 T4128 T4126 pobj gene,of
R2267 T4129 T4128 nmod mouse,gene
R2268 T4130 T4128 nmod GATA,gene
R2269 T4131 T4130 punct -,GATA
R2270 T4132 T4130 nummod 1,GATA
R2271 T4133 T4128 punct (,gene
R2272 T4134 T4135 compound GATA1,cre
R2273 T4135 T4128 appos cre,gene
R2274 T4136 T4135 punct -,cre
R2275 T4137 T4094 punct ),crossed
R2276 T4138 T4139 punct [,14
R2277 T4139 T4094 parataxis 14,crossed
R2278 T4140 T4139 punct ],14
R2279 T4141 T4094 punct .,crossed
R2280 T4143 T4144 amod Widespread,expression
R2281 T4144 T4145 nsubjpass expression,demonstrated
R2282 T4146 T4144 prep of,expression
R2283 T4147 T4148 det the,transgene
R2284 T4148 T4146 pobj transgene,of
R2285 T4149 T4150 compound GATA1,cre
R2286 T4150 T4148 compound cre,transgene
R2287 T4151 T4150 punct -,cre
R2288 T4152 T4145 aux has,demonstrated
R2289 T4153 T4145 auxpass been,demonstrated
R2290 T4154 T4145 prep during,demonstrated
R2291 T4155 T4156 amod early,embryogenesis
R2292 T4156 T4154 pobj embryogenesis,during
R2293 T4157 T4158 punct [,14
R2294 T4158 T4145 parataxis 14,demonstrated
R2295 T4159 T4158 punct ],14
R2296 T4160 T4145 punct .,demonstrated
R2297 T4162 T4163 nsubj We,defined
R2298 T4164 T4165 advmod more,accurately
R2299 T4165 T4163 advmod accurately,defined
R2300 T4166 T4167 det the,onset
R2301 T4167 T4163 dobj onset,defined
R2302 T4168 T4167 prep of,onset
R2303 T4169 T4170 compound GATA1,cre
R2304 T4170 T4172 compound cre,expression
R2305 T4171 T4170 punct -,cre
R2306 T4172 T4168 pobj expression,of
R2307 T4173 T4163 advcl using,defined
R2308 T4174 T4175 det a,strain
R2309 T4175 T4173 dobj strain,using
R2310 T4176 T4175 compound ROSA26,strain
R2311 T4177 T4175 compound reporter,strain
R2312 T4178 T4175 punct ", ",strain
R2313 T4179 T4180 prep in,expressed
R2314 T4180 T4175 relcl expressed,strain
R2315 T4181 T4179 pobj which,in
R2316 T4182 T4183 det a,gene
R2317 T4183 T4180 nsubjpass gene,expressed
R2318 T4184 T4185 nmod β,galactosidase
R2319 T4185 T4187 nmod galactosidase,fusion
R2320 T4186 T4185 punct -,galactosidase
R2321 T4187 T4183 compound fusion,gene
R2322 T4188 T4185 punct /,galactosidase
R2323 T4189 T4185 appos neor,galactosidase
R2324 T4190 T4183 compound reporter,gene
R2325 T4191 T4180 auxpass is,expressed
R2326 T4192 T4193 advmod only,after
R2327 T4193 T4180 prep after,expressed
R2328 T4194 T4195 npadvmod Cre,mediated
R2329 T4195 T4197 amod mediated,excision
R2330 T4196 T4195 punct -,mediated
R2331 T4197 T4193 pobj excision,after
R2332 T4198 T4197 prep of,excision
R2333 T4199 T4200 npadvmod loxP,flanked
R2334 T4200 T4202 amod flanked,transcription
R2335 T4201 T4200 punct -,flanked
R2336 T4202 T4198 pobj transcription,of
R2337 T4203 T4197 cc and,excision
R2338 T4204 T4205 compound translation,termination
R2339 T4205 T4206 compound termination,signals
R2340 T4206 T4197 conj signals,excision
R2341 T4207 T4208 punct [,14
R2342 T4208 T4163 parataxis 14,defined
R2343 T4209 T4208 punct ],14
R2344 T4210 T4163 punct .,defined
R2345 T4212 T4213 nsubj We,found
R2346 T4214 T4215 mark that,was
R2347 T4215 T4213 ccomp was,found
R2348 T4216 T4217 det the,transgene
R2349 T4217 T4215 nsubj transgene,was
R2350 T4218 T4219 compound GATA1,cre
R2351 T4219 T4217 compound cre,transgene
R2352 T4220 T4219 punct -,cre
R2353 T4221 T4215 advmod already,was
R2354 T4222 T4215 acomp active,was
R2355 T4223 T4215 prep at,was
R2356 T4224 T4225 det the,stage
R2357 T4225 T4223 pobj stage,at
R2358 T4226 T4227 nummod 16,cell
R2359 T4227 T4225 compound cell,stage
R2360 T4228 T4227 punct -,cell
R2361 T4229 T4225 compound morula,stage
R2362 T4230 T4225 prep of,stage
R2363 T4231 T4230 pobj development,of
R2364 T4232 T4225 punct (,stage
R2365 T4233 T4234 nummod 0.5,days
R2366 T4234 T4235 npadvmod days,postcoitus
R2367 T4235 T4225 advmod postcoitus,stage
R2368 T4236 T4237 punct [,dpc
R2369 T4237 T4235 parataxis dpc,postcoitus
R2370 T4238 T4237 punct ],dpc
R2371 T4239 T4213 punct ),found
R2372 T4240 T4241 punct (,4A
R2373 T4241 T4213 parataxis 4A,found
R2374 T4242 T4241 compound Figure,4A
R2375 T4243 T4241 punct ),4A
R2376 T4244 T4213 punct .,found

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T3679 31-35 PR_EXT:000004503 denotes Atrx
T3680 36-43 CHEBI_PR_EXT:protein denotes protein
T3681 51-56 NCBITaxon:10088 denotes mouse
T3682 104-108 NCBITaxon:10088 denotes mice
T3683 121-125 PR_EXT:000004503 denotes Atrx
T3684 126-130 SO:0000359 denotes flox
T3685 131-137 SO_EXT:0001023 denotes allele
T3686 166-170 PR_EXT:000004503 denotes Atrx
T3687 171-175 SO:0000359 denotes flox
T3688 176-183 CL:0002322 denotes ES cell
T3689 179-183 CL_GO_EXT:cell denotes cell
T3690 184-190 SO_EXT:sequence_cloned_entity denotes clones
T3691 203-207 PATO_UBERON_EXT:male_or_bearer_of_maleness denotes male
T3692 245-256 UBERON:0000358 denotes blastocysts
T3693 278-282 NCBITaxon:10088 denotes mice
T3694 359-364 PATO_UBERON_EXT:male_or_bearer_of_maleness denotes males
T3695 377-381 PR_EXT:000004503 denotes Atrx
T3696 382-386 SO:0000359 denotes flox
T3697 394-401 PATO_UBERON_EXT:female_or_bearer_of_femaleness denotes females
T3698 416-420 PR_EXT:000004503 denotes Atrx
T3699 421-423 SO_EXT:wild_type_entity_or_quality denotes WT
T3700 424-428 SO:0000359 denotes flox
T3701 438-444 SO:0000359 denotes floxed
T3702 445-451 SO_EXT:0001023 denotes allele
T3703 497-504 PATO_UBERON_EXT:female_or_bearer_of_femaleness denotes females
T3704 506-510 PR_EXT:000004503 denotes Atrx
T3705 511-515 SO:0000359 denotes flox
T3706 516-520 SO:0000359 denotes flox
T3707 523-528 PATO_UBERON_EXT:male_or_bearer_of_maleness denotes Males
T3708 544-551 PATO_UBERON_EXT:female_or_bearer_of_femaleness denotes females
T3709 587-591 PR_EXT:000004503 denotes Atrx
T3710 592-596 SO:0000359 denotes flox
T3711 597-603 SO_EXT:0001023 denotes allele
T3712 639-643 GO_EXT:breeding denotes bred
T3713 688-692 PR_EXT:000004503 denotes Atrx
T3714 693-697 SO:0000359 denotes flox
T3715 698-704 SO_EXT:0001023 denotes allele
T3716 742-746 PR_EXT:000004503 denotes Atrx
T3717 746-750 SO_EXT:sequence_nullness denotes null
T3718 751-755 NCBITaxon:10088 denotes mice
T3719 772-785 GO_SO_EXT:sequence_rearrangement_process denotes recombination
T3720 791-795 PR_EXT:000004503 denotes Atrx
T3721 796-800 SO:0000359 denotes flox
T3722 801-805 NCBITaxon:10088 denotes mice
T3723 824-828 NCBITaxon:10088 denotes mice
T3724 841-850 SO_EXT:0000902 denotes transgene
T3725 868-879 GO_EXT:recombinase denotes recombinase
T3726 883-892 GO:0010467 denotes expressed
T3727 903-910 GO:0065007 denotes control
T3728 918-928 GO:0065007 denotes regulatory
T3729 918-937 SO_EXT:0005836 denotes regulatory elements
T3730 945-950 NCBITaxon:10088 denotes mouse
T3731 951-957 PR_EXT:000007857 denotes GATA-1
T3732 958-962 SO_EXT:0000704 denotes gene
T3733 964-969 PR_EXT:000007857 denotes GATA1
T3734 992-1002 GO:0010467 denotes expression
T3735 1010-1015 PR_EXT:000007857 denotes GATA1
T3736 1020-1029 SO_EXT:0000902 denotes transgene
T3737 1065-1078 GO:0009790 denotes embryogenesis
T3738 1125-1130 PR_EXT:000007857 denotes GATA1
T3739 1135-1145 GO:0010467 denotes expression
T3740 1189-1204 GO_EXT:0004565 denotes β-galactosidase
T3741 1205-1209 GO_EXT:0008910 denotes neor
T3742 1210-1216 _FRAGMENT denotes fusion
T3743 1226-1230 SO_EXT:fusion_gene_or_gene_fusion denotes gene
T3744 1234-1243 GO:0010467 denotes expressed
T3745 1268-1276 SO_EXT:sequence_deletion_process denotes excision
T3746 1280-1292 SO:0000359 denotes loxP-flanked
T3747 1293-1306 GO_EXT:transcription denotes transcription
T3748 1293-1306 _FRAGMENT denotes transcription
T3749 1323-1342 SO_EXT:0000141 denotes termination signals
T3750 1311-1334 GO:0006415 denotes translation termination
T3751 1311-1342 SO_EXT:0000319 denotes translation termination signals
T3752 1367-1372 PR_EXT:000007857 denotes GATA1
T3753 1377-1386 SO_EXT:0000902 denotes transgene
T3754 1416-1420 CL_GO_EXT:cell denotes cell
T3755 1421-1427 UBERON:0000085 denotes morula
T3756 1463-1469 GO:0007620 denotes coitus
R2101 T3743 T3742 _lexicallyChainedTo gene,fusion
R2102 T3749 T3748 _lexicallyChainedTo termination signals,transcription

2_test

Id Subject Object Predicate Lexical cue
16628246-10220414-85799750 976-978 10220414 denotes 14
16628246-10220414-85799751 1080-1082 10220414 denotes 14
16628246-10220414-85799752 1344-1346 10220414 denotes 14
T2364 976-978 10220414 denotes 14
T19888 1080-1082 10220414 denotes 14
T76730 1344-1346 10220414 denotes 14

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T3486 31-35 PR:000004503 denotes Atrx
T3487 51-56 NCBITaxon:10088 denotes mouse
T3488 104-108 NCBITaxon:10088 denotes mice
T3489 121-125 PR:000004503 denotes Atrx
T3490 126-130 SO:0000359 denotes flox
T3491 131-137 SO:0001023 denotes allele
T3492 166-170 PR:000004503 denotes Atrx
T3493 171-175 SO:0000359 denotes flox
T3494 176-183 CL:0002322 denotes ES cell
T3495 245-256 UBERON:0000358 denotes blastocysts
T3496 278-282 NCBITaxon:10088 denotes mice
T3497 377-381 PR:000004503 denotes Atrx
T3498 382-386 SO:0000359 denotes flox
T3499 416-420 PR:000004503 denotes Atrx
T3500 424-428 SO:0000359 denotes flox
T3501 438-444 SO:0000359 denotes floxed
T3502 445-451 SO:0001023 denotes allele
T3503 506-510 PR:000004503 denotes Atrx
T3504 511-515 SO:0000359 denotes flox
T3505 516-520 SO:0000359 denotes flox
T3506 587-591 PR:000004503 denotes Atrx
T3507 592-596 SO:0000359 denotes flox
T3508 597-603 SO:0001023 denotes allele
T3509 688-692 PR:000004503 denotes Atrx
T3510 693-697 SO:0000359 denotes flox
T3511 698-704 SO:0001023 denotes allele
T3512 742-746 PR:000004503 denotes Atrx
T3513 751-755 NCBITaxon:10088 denotes mice
T3514 791-795 PR:000004503 denotes Atrx
T3515 796-800 SO:0000359 denotes flox
T3516 801-805 NCBITaxon:10088 denotes mice
T3517 824-828 NCBITaxon:10088 denotes mice
T3518 841-850 SO:0000902 denotes transgene
T3519 883-892 GO:0010467 denotes expressed
T3520 903-910 GO:0065007 denotes control
T3521 918-928 GO:0065007 denotes regulatory
T3522 918-937 SO:0005836 denotes regulatory elements
T3523 945-950 NCBITaxon:10088 denotes mouse
T3524 951-957 PR:000007857 denotes GATA-1
T3525 958-962 SO:0000704 denotes gene
T3526 964-969 PR:000007857 denotes GATA1
T3527 992-1002 GO:0010467 denotes expression
T3528 1010-1015 PR:000007857 denotes GATA1
T3529 1020-1029 SO:0000902 denotes transgene
T3530 1065-1078 GO:0009790 denotes embryogenesis
T3531 1125-1130 PR:000007857 denotes GATA1
T3532 1135-1145 GO:0010467 denotes expression
T3533 1234-1243 GO:0010467 denotes expressed
T3534 1280-1292 SO:0000359 denotes loxP-flanked
T3535 1293-1306 _FRAGMENT denotes transcription
T3536 1323-1342 SO:0000141 denotes termination signals
T3537 1311-1334 GO:0006415 denotes translation termination
T3538 1311-1342 SO:0000319 denotes translation termination signals
T3539 1367-1372 PR:000007857 denotes GATA1
T3540 1377-1386 SO:0000902 denotes transgene
T3541 1421-1427 UBERON:0000085 denotes morula
T3542 1463-1469 GO:0007620 denotes coitus
R2098 T3536 T3535 _lexicallyChainedTo termination signals,transcription