PMC:1440874 / 12652-12885 JSONTXT

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{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T2379","span":{"begin":16,"end":20},"obj":"PR_EXT:000004503"},{"id":"T2380","span":{"begin":20,"end":24},"obj":"SO_EXT:sequence_nullness"},{"id":"T2381","span":{"begin":25,"end":33},"obj":"CL:0002322"},{"id":"T2382","span":{"begin":28,"end":33},"obj":"CL_GO_EXT:cell"},{"id":"T2383","span":{"begin":178,"end":182},"obj":"PR_EXT:000004503"},{"id":"T2384","span":{"begin":218,"end":225},"obj":"CL:0002322"},{"id":"T2385","span":{"begin":221,"end":225},"obj":"CL_GO_EXT:cell"},{"id":"T2386","span":{"begin":226,"end":232},"obj":"GO_EXT:biological_growth_entity_or_process"}],"text":" Thus, although Atrxnull ES cells could be recovered and maintained in culture by a conditional targeting approach, these cocultivation experiments suggested that the absence of Atrx does negatively impact upon normal ES cell growth."}

{"project":"craft-ca-core-dev","denotations":[{"id":"T2247","span":{"begin":16,"end":20},"obj":"PR:000004503"},{"id":"T2248","span":{"begin":25,"end":33},"obj":"CL:0002322"},{"id":"T2249","span":{"begin":178,"end":182},"obj":"PR:000004503"},{"id":"T2250","span":{"begin":218,"end":225},"obj":"CL:0002322"}],"text":" Thus, although Atrxnull ES cells could be recovered and maintained in culture by a conditional targeting approach, these cocultivation experiments suggested that the absence of Atrx does negatively impact upon normal ES cell growth."}