Id |
Subject |
Object |
Predicate |
Lexical cue |
T226 |
449-451 |
IN |
denotes |
of |
T152 |
0-4 |
NN |
denotes |
Loss |
T153 |
13-20 |
VBZ |
denotes |
Affects |
T154 |
0-104 |
sentence |
denotes |
Loss of Atrx Affects Trophoblast Development and the Pattern of X-Inactivation in Extraembryonic Tissues |
T155 |
5-7 |
IN |
denotes |
of |
T156 |
8-12 |
NN |
denotes |
Atrx |
T157 |
21-32 |
NN |
denotes |
Trophoblast |
T158 |
33-44 |
NN |
denotes |
Development |
T159 |
45-48 |
CC |
denotes |
and |
T161 |
53-60 |
NN |
denotes |
Pattern |
T162 |
61-63 |
IN |
denotes |
of |
T163 |
64-65 |
NN |
denotes |
X |
T164 |
66-78 |
NN |
denotes |
Inactivation |
T165 |
65-66 |
HYPH |
denotes |
- |
T166 |
79-81 |
IN |
denotes |
in |
T167 |
82-96 |
JJ |
denotes |
Extraembryonic |
T168 |
97-104 |
NNS |
denotes |
Tissues |
T169 |
104-105 |
sentence |
denotes |
|
T170 |
155-304 |
sentence |
denotes |
ATRX is an X-encoded member of the SNF2 family of ATPase/helicase proteins thought to regulate gene expression by modifying chromatin at target loci. |
T171 |
155-159 |
NN |
denotes |
ATRX |
T172 |
160-162 |
VBZ |
denotes |
is |
T173 |
163-165 |
DT |
denotes |
an |
T174 |
176-182 |
NN |
denotes |
member |
T175 |
166-167 |
NN |
denotes |
X |
T176 |
167-168 |
HYPH |
denotes |
- |
T177 |
168-175 |
VBN |
denotes |
encoded |
T178 |
183-185 |
IN |
denotes |
of |
T179 |
186-189 |
DT |
denotes |
the |
T180 |
195-201 |
NN |
denotes |
family |
T181 |
190-194 |
NN |
denotes |
SNF2 |
T182 |
202-204 |
IN |
denotes |
of |
T183 |
205-211 |
NN |
denotes |
ATPase |
T184 |
212-220 |
NN |
denotes |
helicase |
T185 |
211-212 |
HYPH |
denotes |
/ |
T186 |
221-229 |
NN |
denotes |
proteins |
T187 |
230-237 |
VBN |
denotes |
thought |
T188 |
238-240 |
TO |
denotes |
to |
T189 |
241-249 |
VB |
denotes |
regulate |
T190 |
250-254 |
NN |
denotes |
gene |
T191 |
255-265 |
NN |
denotes |
expression |
T192 |
266-268 |
IN |
denotes |
by |
T193 |
269-278 |
VBG |
denotes |
modifying |
T194 |
279-288 |
NN |
denotes |
chromatin |
T195 |
289-291 |
IN |
denotes |
at |
T196 |
292-298 |
NN |
denotes |
target |
T197 |
299-303 |
NNS |
denotes |
loci |
T198 |
303-304 |
. |
denotes |
. |
T199 |
304-418 |
sentence |
denotes |
Mutations in ATRX provided the first example of a human genetic disease associated with defects in such proteins. |
T200 |
305-314 |
NNS |
denotes |
Mutations |
T201 |
323-331 |
VBD |
denotes |
provided |
T202 |
315-317 |
IN |
denotes |
in |
T203 |
318-322 |
NN |
denotes |
ATRX |
T204 |
332-335 |
DT |
denotes |
the |
T205 |
342-349 |
NN |
denotes |
example |
T206 |
336-341 |
JJ |
denotes |
first |
T207 |
350-352 |
IN |
denotes |
of |
T208 |
353-354 |
DT |
denotes |
a |
T209 |
369-376 |
NN |
denotes |
disease |
T210 |
355-360 |
JJ |
denotes |
human |
T211 |
361-368 |
JJ |
denotes |
genetic |
T212 |
377-387 |
VBN |
denotes |
associated |
T213 |
388-392 |
IN |
denotes |
with |
T214 |
393-400 |
NNS |
denotes |
defects |
T215 |
401-403 |
IN |
denotes |
in |
T216 |
404-408 |
JJ |
denotes |
such |
T217 |
409-417 |
NN |
denotes |
proteins |
T218 |
417-418 |
. |
denotes |
. |
T219 |
418-675 |
sentence |
denotes |
To better understand the role of ATRX in development and the associated abnormalities in the ATR-X (alpha thalassemia mental retardation, X-linked) syndrome, we conditionally inactivated the homolog in mice, Atrx, at the 8- to 16-cell stage of development. |
T220 |
419-421 |
TO |
denotes |
To |
T221 |
429-439 |
VB |
denotes |
understand |
T222 |
422-428 |
RBR |
denotes |
better |
T223 |
594-605 |
VBD |
denotes |
inactivated |
T224 |
440-443 |
DT |
denotes |
the |
T225 |
444-448 |
NN |
denotes |
role |
T227 |
452-456 |
NN |
denotes |
ATRX |
T228 |
457-459 |
IN |
denotes |
in |
T229 |
460-471 |
NN |
denotes |
development |
T230 |
472-475 |
CC |
denotes |
and |
T231 |
476-479 |
DT |
denotes |
the |
T232 |
491-504 |
NNS |
denotes |
abnormalities |
T233 |
480-490 |
VBN |
denotes |
associated |
T234 |
505-507 |
IN |
denotes |
in |
T235 |
508-511 |
DT |
denotes |
the |
T236 |
567-575 |
NN |
denotes |
syndrome |
T237 |
512-515 |
NN |
denotes |
ATR |
T238 |
516-517 |
NN |
denotes |
X |
T239 |
515-516 |
HYPH |
denotes |
- |
T240 |
518-519 |
-LRB- |
denotes |
( |
T241 |
519-524 |
NN |
denotes |
alpha |
T242 |
525-536 |
NN |
denotes |
thalassemia |
T243 |
537-543 |
JJ |
denotes |
mental |
T244 |
544-555 |
NN |
denotes |
retardation |
T245 |
555-557 |
, |
denotes |
, |
T246 |
557-558 |
NN |
denotes |
X |
T247 |
559-565 |
VBN |
denotes |
linked |
T248 |
558-559 |
HYPH |
denotes |
- |
T249 |
565-566 |
-RRB- |
denotes |
) |
T250 |
575-577 |
, |
denotes |
, |
T251 |
577-579 |
PRP |
denotes |
we |
T252 |
580-593 |
RB |
denotes |
conditionally |
T253 |
606-609 |
DT |
denotes |
the |
T254 |
610-617 |
NN |
denotes |
homolog |
T255 |
618-620 |
IN |
denotes |
in |
T256 |
621-625 |
NNS |
denotes |
mice |
T257 |
625-627 |
, |
denotes |
, |
T258 |
627-631 |
NN |
denotes |
Atrx |
T259 |
631-633 |
, |
denotes |
, |
T260 |
633-635 |
IN |
denotes |
at |
T261 |
636-639 |
DT |
denotes |
the |
T262 |
654-659 |
NN |
denotes |
stage |
T263 |
640-641 |
CD |
denotes |
8 |
T264 |
646-648 |
CD |
denotes |
16 |
T265 |
641-642 |
HYPH |
denotes |
- |
T266 |
643-645 |
IN |
denotes |
to |
T267 |
649-653 |
NN |
denotes |
cell |
T268 |
648-649 |
HYPH |
denotes |
- |
T269 |
660-662 |
IN |
denotes |
of |
T270 |
663-674 |
NN |
denotes |
development |
T271 |
674-675 |
. |
denotes |
. |
T272 |
675-977 |
sentence |
denotes |
The protein, Atrx, was ubiquitously expressed, and male embryos null for Atrx implanted and gastrulated normally but did not survive beyond 9.5 days postcoitus due to a defect in formation of the extraembryonic trophoblast, one of the first terminally differentiated lineages in the developing embryo. |
T273 |
676-679 |
DT |
denotes |
The |
T274 |
680-687 |
NN |
denotes |
protein |
T275 |
712-721 |
VBN |
denotes |
expressed |
T276 |
687-689 |
, |
denotes |
, |
T277 |
689-693 |
NN |
denotes |
Atrx |
T278 |
693-695 |
, |
denotes |
, |
T279 |
695-698 |
VBD |
denotes |
was |
T280 |
699-711 |
RB |
denotes |
ubiquitously |
T281 |
721-723 |
, |
denotes |
, |
T282 |
723-726 |
CC |
denotes |
and |
T283 |
727-731 |
JJ |
denotes |
male |
T284 |
732-739 |
NNS |
denotes |
embryos |
T285 |
754-763 |
VBN |
denotes |
implanted |
T286 |
740-744 |
JJ |
denotes |
null |
T287 |
745-748 |
IN |
denotes |
for |
T288 |
749-753 |
NN |
denotes |
Atrx |
T289 |
764-767 |
CC |
denotes |
and |
T290 |
768-779 |
VBN |
denotes |
gastrulated |
T291 |
780-788 |
RB |
denotes |
normally |
T292 |
789-792 |
CC |
denotes |
but |
T293 |
793-796 |
VBD |
denotes |
did |
T294 |
801-808 |
VB |
denotes |
survive |
T295 |
797-800 |
RB |
denotes |
not |
T296 |
809-815 |
IN |
denotes |
beyond |
T297 |
816-819 |
CD |
denotes |
9.5 |
T298 |
820-824 |
NNS |
denotes |
days |
T299 |
825-835 |
RB |
denotes |
postcoitus |
T300 |
836-839 |
IN |
denotes |
due |
T301 |
840-842 |
IN |
denotes |
to |
T302 |
843-844 |
DT |
denotes |
a |
T303 |
845-851 |
NN |
denotes |
defect |
T304 |
852-854 |
IN |
denotes |
in |
T305 |
855-864 |
NN |
denotes |
formation |
T306 |
865-867 |
IN |
denotes |
of |
T307 |
868-871 |
DT |
denotes |
the |
T308 |
887-898 |
NN |
denotes |
trophoblast |
T309 |
872-886 |
JJ |
denotes |
extraembryonic |
T310 |
898-900 |
, |
denotes |
, |
T311 |
900-903 |
CD |
denotes |
one |
T312 |
904-906 |
IN |
denotes |
of |
T313 |
907-910 |
DT |
denotes |
the |
T314 |
943-951 |
NNS |
denotes |
lineages |
T315 |
911-916 |
JJ |
denotes |
first |
T316 |
917-927 |
RB |
denotes |
terminally |
T317 |
928-942 |
VBN |
denotes |
differentiated |
T318 |
952-954 |
IN |
denotes |
in |
T319 |
955-958 |
DT |
denotes |
the |
T320 |
970-976 |
NN |
denotes |
embryo |
T321 |
959-969 |
VBG |
denotes |
developing |
T322 |
976-977 |
. |
denotes |
. |
T323 |
977-1136 |
sentence |
denotes |
Carrier female mice that inherit a maternal null allele should be affected, since the paternal X chromosome is normally inactivated in extraembryonic tissues. |
T324 |
978-985 |
NN |
denotes |
Carrier |
T325 |
993-997 |
NNS |
denotes |
mice |
T326 |
986-992 |
JJ |
denotes |
female |
T327 |
1044-1052 |
VBN |
denotes |
affected |
T328 |
998-1002 |
WDT |
denotes |
that |
T329 |
1003-1010 |
VBP |
denotes |
inherit |
T330 |
1011-1012 |
DT |
denotes |
a |
T331 |
1027-1033 |
NN |
denotes |
allele |
T332 |
1013-1021 |
JJ |
denotes |
maternal |
T333 |
1022-1026 |
JJ |
denotes |
null |
T334 |
1034-1040 |
MD |
denotes |
should |
T335 |
1041-1043 |
VB |
denotes |
be |
T336 |
1052-1054 |
, |
denotes |
, |
T337 |
1054-1059 |
IN |
denotes |
since |
T338 |
1086-1088 |
VBZ |
denotes |
is |
T339 |
1060-1063 |
DT |
denotes |
the |
T340 |
1075-1085 |
NN |
denotes |
chromosome |
T341 |
1064-1072 |
JJ |
denotes |
paternal |
T342 |
1073-1074 |
NN |
denotes |
X |
T343 |
1089-1097 |
RB |
denotes |
normally |
T344 |
1098-1109 |
JJ |
denotes |
inactivated |
T345 |
1110-1112 |
IN |
denotes |
in |
T346 |
1113-1127 |
JJ |
denotes |
extraembryonic |
T347 |
1128-1135 |
NNS |
denotes |
tissues |
T348 |
1135-1136 |
. |
denotes |
. |
T349 |
1136-1297 |
sentence |
denotes |
Surprisingly, however, some carrier females established a normal placenta and appeared to escape the usual pattern of imprinted X-inactivation in these tissues. |
T350 |
1137-1149 |
RB |
denotes |
Surprisingly |
T351 |
1181-1192 |
VBD |
denotes |
established |
T352 |
1149-1151 |
, |
denotes |
, |
T353 |
1151-1158 |
RB |
denotes |
however |
T354 |
1158-1160 |
, |
denotes |
, |
T355 |
1160-1164 |
DT |
denotes |
some |
T356 |
1173-1180 |
NNS |
denotes |
females |
T357 |
1165-1172 |
NN |
denotes |
carrier |
T358 |
1193-1194 |
DT |
denotes |
a |
T359 |
1202-1210 |
NN |
denotes |
placenta |
T360 |
1195-1201 |
JJ |
denotes |
normal |
T361 |
1211-1214 |
CC |
denotes |
and |
T362 |
1215-1223 |
VBD |
denotes |
appeared |
T363 |
1224-1226 |
TO |
denotes |
to |
T364 |
1227-1233 |
VB |
denotes |
escape |
T365 |
1234-1237 |
DT |
denotes |
the |
T366 |
1244-1251 |
NN |
denotes |
pattern |
T367 |
1238-1243 |
JJ |
denotes |
usual |
T368 |
1252-1254 |
IN |
denotes |
of |
T369 |
1255-1264 |
VBN |
denotes |
imprinted |
T370 |
1267-1279 |
NN |
denotes |
inactivation |
T371 |
1265-1266 |
NN |
denotes |
X |
T372 |
1266-1267 |
HYPH |
denotes |
- |
T373 |
1280-1282 |
IN |
denotes |
in |
T374 |
1283-1288 |
DT |
denotes |
these |
T375 |
1289-1296 |
NNS |
denotes |
tissues |
T376 |
1296-1297 |
. |
denotes |
. |
T377 |
1297-1506 |
sentence |
denotes |
Together these findings demonstrate an unexpected, specific, and essential role for Atrx in the development of the murine trophoblast and present an example of escape from imprinted X chromosome inactivation. |
T378 |
1298-1306 |
RB |
denotes |
Together |
T379 |
1322-1333 |
VBP |
denotes |
demonstrate |
T380 |
1307-1312 |
DT |
denotes |
these |
T381 |
1313-1321 |
NNS |
denotes |
findings |
T382 |
1334-1336 |
DT |
denotes |
an |
T383 |
1373-1377 |
NN |
denotes |
role |
T384 |
1337-1347 |
JJ |
denotes |
unexpected |
T385 |
1347-1349 |
, |
denotes |
, |
T386 |
1349-1357 |
JJ |
denotes |
specific |
T387 |
1357-1359 |
, |
denotes |
, |
T388 |
1359-1362 |
CC |
denotes |
and |
T389 |
1363-1372 |
JJ |
denotes |
essential |
T390 |
1378-1381 |
IN |
denotes |
for |
T391 |
1382-1386 |
NN |
denotes |
Atrx |
T392 |
1387-1389 |
IN |
denotes |
in |
T393 |
1390-1393 |
DT |
denotes |
the |
T394 |
1394-1405 |
NN |
denotes |
development |
T395 |
1406-1408 |
IN |
denotes |
of |
T396 |
1409-1412 |
DT |
denotes |
the |
T397 |
1420-1431 |
NN |
denotes |
trophoblast |
T398 |
1413-1419 |
JJ |
denotes |
murine |
T399 |
1432-1435 |
CC |
denotes |
and |
T400 |
1436-1443 |
VBP |
denotes |
present |
T401 |
1444-1446 |
DT |
denotes |
an |
T402 |
1447-1454 |
NN |
denotes |
example |
T403 |
1455-1457 |
IN |
denotes |
of |
T404 |
1458-1464 |
NN |
denotes |
escape |
T405 |
1465-1469 |
IN |
denotes |
from |
T406 |
1470-1479 |
VBN |
denotes |
imprinted |
T407 |
1482-1492 |
NN |
denotes |
chromosome |
T408 |
1480-1481 |
NN |
denotes |
X |
T409 |
1493-1505 |
NN |
denotes |
inactivation |
T410 |
1505-1506 |
. |
denotes |
. |
T160 |
49-52 |
DT |
denotes |
the |
R7 |
T161 |
T158 |
conj |
Pattern,Development |
R8 |
T162 |
T161 |
prep |
of,Pattern |
R9 |
T163 |
T164 |
compound |
X,Inactivation |
R10 |
T164 |
T162 |
pobj |
Inactivation,of |
R12 |
T166 |
T153 |
prep |
in,Affects |
R13 |
T167 |
T168 |
amod |
Extraembryonic,Tissues |
R14 |
T168 |
T166 |
pobj |
Tissues,in |
R15 |
T171 |
T172 |
nsubj |
ATRX,is |
R16 |
T173 |
T174 |
det |
an,member |
R17 |
T174 |
T172 |
attr |
member,is |
R21 |
T178 |
T174 |
prep |
of,member |
R22 |
T179 |
T180 |
det |
the,family |
R23 |
T180 |
T178 |
pobj |
family,of |
R25 |
T182 |
T180 |
prep |
of,family |
R26 |
T183 |
T184 |
compound |
ATPase,helicase |
R27 |
T184 |
T186 |
compound |
helicase,proteins |
R29 |
T186 |
T182 |
pobj |
proteins,of |
R30 |
T187 |
T174 |
acl |
thought,member |
R31 |
T188 |
T189 |
aux |
to,regulate |
R32 |
T189 |
T187 |
xcomp |
regulate,thought |
R33 |
T190 |
T191 |
compound |
gene,expression |
R34 |
T191 |
T189 |
dobj |
expression,regulate |
R35 |
T192 |
T189 |
prep |
by,regulate |
R36 |
T193 |
T192 |
pcomp |
modifying,by |
R37 |
T194 |
T193 |
dobj |
chromatin,modifying |
R38 |
T195 |
T193 |
prep |
at,modifying |
R39 |
T196 |
T197 |
compound |
target,loci |
R40 |
T197 |
T195 |
pobj |
loci,at |
R41 |
T198 |
T172 |
punct |
.,is |
R42 |
T200 |
T201 |
nsubj |
Mutations,provided |
R43 |
T202 |
T200 |
prep |
in,Mutations |
R44 |
T203 |
T202 |
pobj |
ATRX,in |
R45 |
T204 |
T205 |
det |
the,example |
R46 |
T205 |
T201 |
dobj |
example,provided |
R48 |
T207 |
T205 |
prep |
of,example |
R49 |
T208 |
T209 |
det |
a,disease |
R50 |
T209 |
T207 |
pobj |
disease,of |
R53 |
T212 |
T209 |
acl |
associated,disease |
R54 |
T213 |
T212 |
prep |
with,associated |
R55 |
T214 |
T213 |
pobj |
defects,with |
R56 |
T215 |
T214 |
prep |
in,defects |
R57 |
T216 |
T217 |
amod |
such,proteins |
R58 |
T217 |
T215 |
pobj |
proteins,in |
R59 |
T218 |
T201 |
punct |
.,provided |
R60 |
T220 |
T221 |
aux |
To,understand |
R61 |
T221 |
T223 |
advcl |
understand,inactivated |
R63 |
T224 |
T225 |
det |
the,role |
R64 |
T225 |
T221 |
dobj |
role,understand |
R65 |
T226 |
T225 |
prep |
of,role |
R66 |
T227 |
T226 |
pobj |
ATRX,of |
R67 |
T228 |
T225 |
prep |
in,role |
R68 |
T229 |
T228 |
pobj |
development,in |
R69 |
T230 |
T225 |
cc |
and,role |
R70 |
T231 |
T232 |
det |
the,abnormalities |
R71 |
T232 |
T225 |
conj |
abnormalities,role |
R73 |
T234 |
T232 |
prep |
in,abnormalities |
R74 |
T235 |
T236 |
det |
the,syndrome |
R75 |
T236 |
T234 |
pobj |
syndrome,in |
R77 |
T238 |
T236 |
nmod |
X,syndrome |
R78 |
T239 |
T238 |
punct |
-,X |
R86 |
T247 |
T242 |
amod |
linked,thalassemia |
R87 |
T248 |
T247 |
punct |
-,linked |
R89 |
T250 |
T223 |
punct |
", ",inactivated |
R90 |
T251 |
T223 |
nsubj |
we,inactivated |
R91 |
T252 |
T223 |
advmod |
conditionally,inactivated |
R92 |
T253 |
T254 |
det |
the,homolog |
R93 |
T254 |
T223 |
dobj |
homolog,inactivated |
R94 |
T255 |
T254 |
prep |
in,homolog |
R95 |
T256 |
T255 |
pobj |
mice,in |
R96 |
T257 |
T254 |
punct |
", ",homolog |
R97 |
T258 |
T254 |
appos |
Atrx,homolog |
R98 |
T259 |
T223 |
punct |
", ",inactivated |
R99 |
T260 |
T223 |
prep |
at,inactivated |
R100 |
T261 |
T262 |
det |
the,stage |
R101 |
T262 |
T260 |
pobj |
stage,at |
R103 |
T264 |
T267 |
nummod |
16,cell |
R104 |
T265 |
T264 |
punct |
-,16 |
R105 |
T266 |
T264 |
quantmod |
to,16 |
R106 |
T267 |
T262 |
compound |
cell,stage |
R107 |
T268 |
T267 |
punct |
-,cell |
R108 |
T269 |
T262 |
prep |
of,stage |
R109 |
T270 |
T269 |
pobj |
development,of |
R110 |
T271 |
T223 |
punct |
.,inactivated |
R111 |
T273 |
T274 |
det |
The,protein |
R112 |
T274 |
T275 |
nsubjpass |
protein,expressed |
R113 |
T276 |
T274 |
punct |
", ",protein |
R114 |
T277 |
T274 |
appos |
Atrx,protein |
R115 |
T278 |
T275 |
punct |
", ",expressed |
R116 |
T279 |
T275 |
auxpass |
was,expressed |
R117 |
T280 |
T275 |
advmod |
ubiquitously,expressed |
R118 |
T281 |
T275 |
punct |
", ",expressed |
R119 |
T282 |
T275 |
cc |
and,expressed |
R120 |
T283 |
T284 |
amod |
male,embryos |
R121 |
T284 |
T285 |
nsubj |
embryos,implanted |
R122 |
T285 |
T275 |
conj |
implanted,expressed |
R126 |
T289 |
T285 |
cc |
and,implanted |
R127 |
T290 |
T285 |
conj |
gastrulated,implanted |
R128 |
T291 |
T285 |
advmod |
normally,implanted |
R129 |
T292 |
T285 |
cc |
but,implanted |
R130 |
T293 |
T294 |
aux |
did,survive |
R131 |
T294 |
T285 |
conj |
survive,implanted |
R133 |
T296 |
T294 |
prep |
beyond,survive |
R134 |
T297 |
T298 |
nummod |
9.5,days |
R135 |
T298 |
T296 |
pobj |
days,beyond |
R136 |
T299 |
T298 |
advmod |
postcoitus,days |
R137 |
T300 |
T294 |
prep |
due,survive |
R138 |
T301 |
T300 |
pcomp |
to,due |
R139 |
T302 |
T303 |
det |
a,defect |
R140 |
T303 |
T300 |
pobj |
defect,due |
R141 |
T304 |
T303 |
prep |
in,defect |
R142 |
T305 |
T304 |
pobj |
formation,in |
R143 |
T306 |
T305 |
prep |
of,formation |
R144 |
T307 |
T308 |
det |
the,trophoblast |
R145 |
T308 |
T306 |
pobj |
trophoblast,of |
R147 |
T310 |
T308 |
punct |
", ",trophoblast |
R148 |
T311 |
T308 |
appos |
one,trophoblast |
R149 |
T312 |
T311 |
prep |
of,one |
R150 |
T313 |
T314 |
det |
the,lineages |
R151 |
T314 |
T312 |
pobj |
lineages,of |
R155 |
T318 |
T314 |
prep |
in,lineages |
R156 |
T319 |
T320 |
det |
the,embryo |
R157 |
T320 |
T318 |
pobj |
embryo,in |
R159 |
T322 |
T285 |
punct |
.,implanted |
R160 |
T324 |
T325 |
nmod |
Carrier,mice |
R161 |
T325 |
T327 |
nsubjpass |
mice,affected |
R163 |
T328 |
T329 |
dep |
that,inherit |
R164 |
T329 |
T325 |
relcl |
inherit,mice |
R165 |
T330 |
T331 |
det |
a,allele |
R166 |
T331 |
T329 |
dobj |
allele,inherit |
R169 |
T334 |
T327 |
aux |
should,affected |
R170 |
T335 |
T327 |
auxpass |
be,affected |
R171 |
T336 |
T327 |
punct |
", ",affected |
R172 |
T337 |
T338 |
mark |
since,is |
R173 |
T338 |
T327 |
advcl |
is,affected |
R175 |
T340 |
T338 |
nsubj |
chromosome,is |
R176 |
T341 |
T340 |
amod |
paternal,chromosome |
R177 |
T342 |
T340 |
compound |
X,chromosome |
R178 |
T343 |
T338 |
advmod |
normally,is |
R179 |
T344 |
T338 |
acomp |
inactivated,is |
R180 |
T345 |
T338 |
prep |
in,is |
R181 |
T346 |
T347 |
amod |
extraembryonic,tissues |
R182 |
T347 |
T345 |
pobj |
tissues,in |
R183 |
T348 |
T327 |
punct |
.,affected |
R184 |
T350 |
T351 |
advmod |
Surprisingly,established |
R185 |
T352 |
T351 |
punct |
", ",established |
R186 |
T353 |
T351 |
advmod |
however,established |
R187 |
T354 |
T351 |
punct |
", ",established |
R188 |
T355 |
T356 |
det |
some,females |
R189 |
T356 |
T351 |
nsubj |
females,established |
R191 |
T358 |
T359 |
det |
a,placenta |
R192 |
T359 |
T351 |
dobj |
placenta,established |
R194 |
T361 |
T351 |
cc |
and,established |
R195 |
T362 |
T351 |
conj |
appeared,established |
R196 |
T363 |
T364 |
aux |
to,escape |
R197 |
T364 |
T362 |
xcomp |
escape,appeared |
R198 |
T365 |
T366 |
det |
the,pattern |
R199 |
T366 |
T364 |
dobj |
pattern,escape |
R201 |
T368 |
T366 |
prep |
of,pattern |
R202 |
T369 |
T370 |
amod |
imprinted,inactivation |
R203 |
T370 |
T368 |
pobj |
inactivation,of |
R206 |
T373 |
T364 |
prep |
in,escape |
R207 |
T374 |
T375 |
det |
these,tissues |
R208 |
T375 |
T373 |
pobj |
tissues,in |
R209 |
T376 |
T351 |
punct |
.,established |
R210 |
T378 |
T379 |
advmod |
Together,demonstrate |
R211 |
T380 |
T381 |
det |
these,findings |
R212 |
T381 |
T379 |
nsubj |
findings,demonstrate |
R213 |
T382 |
T383 |
det |
an,role |
R214 |
T383 |
T379 |
dobj |
role,demonstrate |
R221 |
T390 |
T383 |
prep |
for,role |
R222 |
T391 |
T390 |
pobj |
Atrx,for |
R223 |
T392 |
T383 |
prep |
in,role |
R224 |
T393 |
T394 |
det |
the,development |
R225 |
T394 |
T392 |
pobj |
development,in |
R226 |
T395 |
T394 |
prep |
of,development |
R227 |
T396 |
T397 |
det |
the,trophoblast |
R228 |
T397 |
T395 |
pobj |
trophoblast,of |
R230 |
T399 |
T379 |
cc |
and,demonstrate |
R231 |
T400 |
T379 |
conj |
present,demonstrate |
R232 |
T401 |
T402 |
det |
an,example |
R233 |
T402 |
T400 |
dobj |
example,present |
R234 |
T403 |
T402 |
prep |
of,example |
R235 |
T404 |
T403 |
pobj |
escape,of |
R236 |
T405 |
T404 |
prep |
from,escape |
R237 |
T406 |
T407 |
amod |
imprinted,chromosome |
R238 |
T407 |
T409 |
compound |
chromosome,inactivation |
R240 |
T409 |
T405 |
pobj |
inactivation,from |
R241 |
T410 |
T379 |
punct |
.,demonstrate |
R242 |
T160 |
T161 |
det |
the,Pattern |
R1 |
T152 |
T153 |
nsubj |
Loss,Affects |
R2 |
T155 |
T152 |
prep |
of,Loss |
R3 |
T156 |
T155 |
pobj |
Atrx,of |
R4 |
T157 |
T158 |
compound |
Trophoblast,Development |
R5 |
T158 |
T153 |
dobj |
Development,Affects |
R6 |
T159 |
T158 |
cc |
and,Development |
R11 |
T165 |
T164 |
punct |
-,Inactivation |
R18 |
T175 |
T174 |
nmod |
X,member |
R19 |
T176 |
T175 |
punct |
-,X |
R20 |
T177 |
T175 |
amod |
encoded,X |
R24 |
T181 |
T180 |
compound |
SNF2,family |
R28 |
T185 |
T184 |
punct |
/,helicase |
R47 |
T206 |
T205 |
amod |
first,example |
R51 |
T210 |
T209 |
amod |
human,disease |
R52 |
T211 |
T209 |
amod |
genetic,disease |
R62 |
T222 |
T221 |
advmod |
better,understand |
R72 |
T233 |
T232 |
amod |
associated,abnormalities |
R76 |
T237 |
T238 |
nmod |
ATR,X |
R79 |
T240 |
T238 |
punct |
(,X |
R80 |
T241 |
T242 |
compound |
alpha,thalassemia |
R81 |
T242 |
T238 |
appos |
thalassemia,X |
R82 |
T243 |
T244 |
amod |
mental,retardation |
R83 |
T244 |
T242 |
appos |
retardation,thalassemia |
R84 |
T245 |
T242 |
punct |
", ",thalassemia |
R85 |
T246 |
T247 |
npadvmod |
X,linked |
R88 |
T249 |
T236 |
punct |
),syndrome |
R102 |
T263 |
T264 |
quantmod |
8,16 |
R123 |
T286 |
T284 |
amod |
null,embryos |
R124 |
T287 |
T286 |
prep |
for,null |
R125 |
T288 |
T287 |
pobj |
Atrx,for |
R132 |
T295 |
T294 |
neg |
not,survive |
R146 |
T309 |
T308 |
amod |
extraembryonic,trophoblast |
R152 |
T315 |
T314 |
amod |
first,lineages |
R153 |
T316 |
T317 |
advmod |
terminally,differentiated |
R154 |
T317 |
T314 |
amod |
differentiated,lineages |
R158 |
T321 |
T320 |
amod |
developing,embryo |
R162 |
T326 |
T325 |
amod |
female,mice |
R167 |
T332 |
T331 |
amod |
maternal,allele |
R168 |
T333 |
T331 |
amod |
null,allele |
R174 |
T339 |
T340 |
det |
the,chromosome |
R190 |
T357 |
T356 |
compound |
carrier,females |
R193 |
T360 |
T359 |
amod |
normal,placenta |
R200 |
T367 |
T366 |
amod |
usual,pattern |
R204 |
T371 |
T370 |
compound |
X,inactivation |
R205 |
T372 |
T370 |
punct |
-,inactivation |
R215 |
T384 |
T383 |
amod |
unexpected,role |
R216 |
T385 |
T384 |
punct |
", ",unexpected |
R217 |
T386 |
T384 |
conj |
specific,unexpected |
R218 |
T387 |
T386 |
punct |
", ",specific |
R219 |
T388 |
T386 |
cc |
and,specific |
R220 |
T389 |
T386 |
conj |
essential,specific |
R229 |
T398 |
T397 |
amod |
murine,trophoblast |
R239 |
T408 |
T407 |
compound |
X,chromosome |