| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1127 |
0-2 |
NN |
denotes |
mr |
| T1128 |
3-4 |
NN |
denotes |
s |
| T1129 |
2-3 |
HYPH |
denotes |
- |
| T1130 |
23-32 |
VBN |
denotes |
conserved |
| T1131 |
5-7 |
VBZ |
denotes |
is |
| T1132 |
8-22 |
RB |
denotes |
evolutionarily |
| T1133 |
33-37 |
IN |
denotes |
from |
| T1134 |
38-47 |
NN |
denotes |
zebrafish |
| T1135 |
48-55 |
IN |
denotes |
through |
| T1136 |
56-61 |
JJ |
denotes |
human |
| T1137 |
61-63 |
, |
denotes |
, |
| T1138 |
63-72 |
NNS |
denotes |
organisms |
| T1139 |
73-80 |
IN |
denotes |
through |
| T1140 |
145-154 |
VBN |
denotes |
conserved |
| T1141 |
81-86 |
WDT |
denotes |
which |
| T1142 |
87-90 |
DT |
denotes |
the |
| T1143 |
91-100 |
NN |
denotes |
mechanism |
| T1144 |
101-103 |
IN |
denotes |
of |
| T1145 |
104-117 |
NN |
denotes |
photoreceptor |
| T1146 |
118-129 |
NN |
denotes |
development |
| T1147 |
130-132 |
VBZ |
denotes |
is |
| T1148 |
133-137 |
RB |
denotes |
also |
| T1149 |
138-144 |
RB |
denotes |
highly |
| T1150 |
154-155 |
. |
denotes |
. |
| T1151 |
155-367 |
sentence |
denotes |
Phylogenetic analysis suggests that the SAM domain of mr-s is most closely related to a mouse polyhomeotic (ph) ortholog, Mph1/Rae28, which is known as an epigenetic molecule involved in chromatin modifications. |
| T1152 |
156-168 |
JJ |
denotes |
Phylogenetic |
| T1153 |
169-177 |
NN |
denotes |
analysis |
| T1154 |
178-186 |
VBZ |
denotes |
suggests |
| T1155 |
187-191 |
IN |
denotes |
that |
| T1156 |
231-238 |
VBN |
denotes |
related |
| T1157 |
192-195 |
DT |
denotes |
the |
| T1158 |
200-206 |
NN |
denotes |
domain |
| T1159 |
196-199 |
NN |
denotes |
SAM |
| T1160 |
207-209 |
IN |
denotes |
of |
| T1161 |
210-212 |
NN |
denotes |
mr |
| T1162 |
213-214 |
NN |
denotes |
s |
| T1163 |
212-213 |
HYPH |
denotes |
- |
| T1164 |
215-217 |
VBZ |
denotes |
is |
| T1165 |
218-222 |
RBS |
denotes |
most |
| T1166 |
223-230 |
RB |
denotes |
closely |
| T1167 |
239-241 |
IN |
denotes |
to |
| T1168 |
242-243 |
DT |
denotes |
a |
| T1169 |
268-276 |
NN |
denotes |
ortholog |
| T1170 |
244-249 |
NN |
denotes |
mouse |
| T1171 |
250-262 |
NN |
denotes |
polyhomeotic |
| T1172 |
263-264 |
-LRB- |
denotes |
( |
| T1173 |
264-266 |
NN |
denotes |
ph |
| T1174 |
266-267 |
-RRB- |
denotes |
) |
| T1175 |
276-278 |
, |
denotes |
, |
| T1176 |
278-282 |
NN |
denotes |
Mph1 |
| T1177 |
283-288 |
NN |
denotes |
Rae28 |
| T1178 |
282-283 |
HYPH |
denotes |
/ |
| T1179 |
288-290 |
, |
denotes |
, |
| T1180 |
290-295 |
WDT |
denotes |
which |
| T1181 |
299-304 |
VBN |
denotes |
known |
| T1182 |
296-298 |
VBZ |
denotes |
is |
| T1183 |
305-307 |
IN |
denotes |
as |
| T1184 |
308-310 |
DT |
denotes |
an |
| T1185 |
322-330 |
NN |
denotes |
molecule |
| T1186 |
311-321 |
JJ |
denotes |
epigenetic |
| T1187 |
331-339 |
VBN |
denotes |
involved |
| T1188 |
340-342 |
IN |
denotes |
in |
| T1189 |
343-352 |
NN |
denotes |
chromatin |
| T1190 |
353-366 |
NNS |
denotes |
modifications |
| T1191 |
366-367 |
. |
denotes |
. |
| T1192 |
367-501 |
sentence |
denotes |
These findings provide the possibility that mr-s may play a critical role by regulating gene expression in photoreceptor development. |
| T1193 |
368-373 |
DT |
denotes |
These |
| T1194 |
374-382 |
NNS |
denotes |
findings |
| T1195 |
383-390 |
VBP |
denotes |
provide |
| T1196 |
391-394 |
DT |
denotes |
the |
| T1197 |
395-406 |
NN |
denotes |
possibility |
| T1198 |
407-411 |
IN |
denotes |
that |
| T1199 |
421-425 |
VB |
denotes |
play |
| T1200 |
412-414 |
NN |
denotes |
mr |
| T1201 |
415-416 |
NN |
denotes |
s |
| T1202 |
414-415 |
HYPH |
denotes |
- |
| T1203 |
417-420 |
MD |
denotes |
may |
| T1204 |
426-427 |
DT |
denotes |
a |
| T1205 |
437-441 |
NN |
denotes |
role |
| T1206 |
428-436 |
JJ |
denotes |
critical |
| T1207 |
442-444 |
IN |
denotes |
by |
| T1208 |
445-455 |
VBG |
denotes |
regulating |
| T1209 |
456-460 |
NN |
denotes |
gene |
| T1210 |
461-471 |
NN |
denotes |
expression |
| T1211 |
472-474 |
IN |
denotes |
in |
| T1212 |
475-488 |
NN |
denotes |
photoreceptor |
| T1213 |
489-500 |
NN |
denotes |
development |
| T1214 |
500-501 |
. |
denotes |
. |
| T1215 |
501-670 |
sentence |
denotes |
mr-s is preferentially expressed in the photoreceptors at postnatal day 3–6 (P3-6), when photoreceptors undergo terminal differentiation, and in the adult pineal gland. |
| T1216 |
502-504 |
NN |
denotes |
mr |
| T1217 |
505-506 |
NN |
denotes |
s |
| T1218 |
504-505 |
HYPH |
denotes |
- |
| T1219 |
525-534 |
VBN |
denotes |
expressed |
| T1220 |
507-509 |
VBZ |
denotes |
is |
| T1221 |
510-524 |
RB |
denotes |
preferentially |
| T1222 |
535-537 |
IN |
denotes |
in |
| T1223 |
538-541 |
DT |
denotes |
the |
| T1224 |
542-556 |
NNS |
denotes |
photoreceptors |
| T1225 |
557-559 |
IN |
denotes |
at |
| T1226 |
560-569 |
JJ |
denotes |
postnatal |
| T1227 |
574-575 |
CD |
denotes |
3 |
| T1228 |
570-573 |
NN |
denotes |
day |
| T1229 |
575-576 |
SYM |
denotes |
– |
| T1230 |
576-577 |
CD |
denotes |
6 |
| T1231 |
578-579 |
-LRB- |
denotes |
( |
| T1232 |
579-581 |
NN |
denotes |
P3 |
| T1233 |
581-582 |
SYM |
denotes |
- |
| T1234 |
582-583 |
CD |
denotes |
6 |
| T1235 |
583-584 |
-RRB- |
denotes |
) |
| T1236 |
584-586 |
, |
denotes |
, |
| T1237 |
586-590 |
WRB |
denotes |
when |
| T1238 |
606-613 |
VBP |
denotes |
undergo |
| T1239 |
591-605 |
NNS |
denotes |
photoreceptors |
| T1240 |
614-622 |
JJ |
denotes |
terminal |
| T1241 |
623-638 |
NN |
denotes |
differentiation |
| T1242 |
638-640 |
, |
denotes |
, |
| T1243 |
640-643 |
CC |
denotes |
and |
| T1244 |
644-646 |
IN |
denotes |
in |
| T1245 |
647-650 |
DT |
denotes |
the |
| T1246 |
664-669 |
NN |
denotes |
gland |
| T1247 |
651-656 |
JJ |
denotes |
adult |
| T1248 |
657-663 |
JJ |
denotes |
pineal |
| T1249 |
669-670 |
. |
denotes |
. |
| T1250 |
670-755 |
sentence |
denotes |
Transcription of mr-s is directly regulated by the cone-rod homeodomain protein Crx. |
| T1251 |
671-684 |
NN |
denotes |
Transcription |
| T1252 |
705-714 |
VBN |
denotes |
regulated |
| T1253 |
685-687 |
IN |
denotes |
of |
| T1254 |
688-690 |
NN |
denotes |
mr |
| T1255 |
691-692 |
NN |
denotes |
s |
| T1256 |
690-691 |
HYPH |
denotes |
- |
| T1257 |
693-695 |
VBZ |
denotes |
is |
| T1258 |
696-704 |
RB |
denotes |
directly |
| T1259 |
715-717 |
IN |
denotes |
by |
| T1260 |
718-721 |
DT |
denotes |
the |
| T1261 |
743-750 |
NN |
denotes |
protein |
| T1262 |
722-726 |
NN |
denotes |
cone |
| T1263 |
727-730 |
NN |
denotes |
rod |
| T1264 |
726-727 |
HYPH |
denotes |
- |
| T1265 |
731-742 |
NN |
denotes |
homeodomain |
| T1266 |
751-754 |
NN |
denotes |
Crx |
| T1267 |
754-755 |
. |
denotes |
. |
| T1268 |
755-889 |
sentence |
denotes |
Immunoprecipitation assay showed that the mr-s protein self-associates mainly through the SAM domain-containing region as well as ph. |
| T1269 |
756-775 |
NN |
denotes |
Immunoprecipitation |
| T1270 |
776-781 |
NN |
denotes |
assay |
| T1271 |
782-788 |
VBD |
denotes |
showed |
| T1272 |
789-793 |
IN |
denotes |
that |
| T1273 |
816-826 |
VBZ |
denotes |
associates |
| T1274 |
794-797 |
DT |
denotes |
the |
| T1275 |
803-810 |
NN |
denotes |
protein |
| T1276 |
798-800 |
NN |
denotes |
mr |
| T1277 |
801-802 |
NN |
denotes |
s |
| T1278 |
800-801 |
HYPH |
denotes |
- |
| T1279 |
811-815 |
NN |
denotes |
self |
| T1280 |
815-816 |
HYPH |
denotes |
- |
| T1281 |
827-833 |
RB |
denotes |
mainly |
| T1282 |
834-841 |
IN |
denotes |
through |
| T1283 |
842-845 |
DT |
denotes |
the |
| T1284 |
868-874 |
NN |
denotes |
region |
| T1285 |
846-849 |
NN |
denotes |
SAM |
| T1286 |
850-856 |
NN |
denotes |
domain |
| T1287 |
857-867 |
VBG |
denotes |
containing |
| T1288 |
856-857 |
HYPH |
denotes |
- |
| T1289 |
875-877 |
RB |
denotes |
as |
| T1290 |
883-885 |
IN |
denotes |
as |
| T1291 |
878-882 |
RB |
denotes |
well |
| T1292 |
886-888 |
NN |
denotes |
ph |
| T1293 |
888-889 |
. |
denotes |
. |
| T1294 |
889-984 |
sentence |
denotes |
The mr-s protein localizes mainly in the nucleus, when mr-s is overexpressed in HEK293T cells. |
| T1295 |
890-893 |
DT |
denotes |
The |
| T1296 |
899-906 |
NN |
denotes |
protein |
| T1297 |
894-896 |
NN |
denotes |
mr |
| T1298 |
897-898 |
NN |
denotes |
s |
| T1299 |
896-897 |
HYPH |
denotes |
- |
| T1300 |
907-916 |
VBZ |
denotes |
localizes |
| T1301 |
917-923 |
RB |
denotes |
mainly |
| T1302 |
924-926 |
IN |
denotes |
in |
| T1303 |
927-930 |
DT |
denotes |
the |
| T1304 |
931-938 |
NN |
denotes |
nucleus |
| T1305 |
938-940 |
, |
denotes |
, |
| T1306 |
940-944 |
WRB |
denotes |
when |
| T1307 |
953-966 |
VBN |
denotes |
overexpressed |
| T1308 |
945-947 |
NN |
denotes |
mr |
| T1309 |
948-949 |
NN |
denotes |
s |
| T1310 |
947-948 |
HYPH |
denotes |
- |
| T1311 |
950-952 |
VBZ |
denotes |
is |
| T1312 |
967-969 |
IN |
denotes |
in |
| T1313 |
970-977 |
NN |
denotes |
HEK293T |
| T1314 |
978-983 |
NNS |
denotes |
cells |
| T1315 |
983-984 |
. |
denotes |
. |
| T1316 |
984-1122 |
sentence |
denotes |
Moreover, in the luciferase assays, we found that mr-s protein fused to GAL4 DNA-binding domain functions as a transcriptional repressor. |
| T1317 |
985-993 |
RB |
denotes |
Moreover |
| T1318 |
1024-1029 |
VBD |
denotes |
found |
| T1319 |
993-995 |
, |
denotes |
, |
| T1320 |
995-997 |
IN |
denotes |
in |
| T1321 |
998-1001 |
DT |
denotes |
the |
| T1322 |
1013-1019 |
NNS |
denotes |
assays |
| T1323 |
1002-1012 |
NN |
denotes |
luciferase |
| T1324 |
1019-1021 |
, |
denotes |
, |
| T1325 |
1021-1023 |
PRP |
denotes |
we |
| T1326 |
1030-1034 |
IN |
denotes |
that |
| T1327 |
1081-1090 |
VBZ |
denotes |
functions |
| T1328 |
1035-1037 |
NN |
denotes |
mr |
| T1329 |
1038-1039 |
NN |
denotes |
s |
| T1330 |
1037-1038 |
HYPH |
denotes |
- |
| T1331 |
1040-1047 |
NN |
denotes |
protein |
| T1332 |
1048-1053 |
VBN |
denotes |
fused |
| T1333 |
1054-1056 |
IN |
denotes |
to |
| T1334 |
1057-1061 |
NN |
denotes |
GAL4 |
| T1335 |
1074-1080 |
NN |
denotes |
domain |
| T1336 |
1062-1065 |
NN |
denotes |
DNA |
| T1337 |
1066-1073 |
VBG |
denotes |
binding |
| T1338 |
1065-1066 |
HYPH |
denotes |
- |
| T1339 |
1091-1093 |
IN |
denotes |
as |
| T1340 |
1094-1095 |
DT |
denotes |
a |
| T1341 |
1112-1121 |
NN |
denotes |
repressor |
| T1342 |
1096-1111 |
JJ |
denotes |
transcriptional |
| T1343 |
1121-1122 |
. |
denotes |
. |
| T1344 |
1122-1263 |
sentence |
denotes |
We revealed that the repression activity of mr-s is not due to a homophilic interaction through its SAM domain but to the C-terminal region. |
| T1345 |
1123-1125 |
PRP |
denotes |
We |
| T1346 |
1126-1134 |
VBD |
denotes |
revealed |
| T1347 |
1135-1139 |
IN |
denotes |
that |
| T1348 |
1172-1174 |
VBZ |
denotes |
is |
| T1349 |
1140-1143 |
DT |
denotes |
the |
| T1350 |
1155-1163 |
NN |
denotes |
activity |
| T1351 |
1144-1154 |
NN |
denotes |
repression |
| T1352 |
1164-1166 |
IN |
denotes |
of |
| T1353 |
1167-1169 |
NN |
denotes |
mr |
| T1354 |
1170-1171 |
NN |
denotes |
s |
| T1355 |
1169-1170 |
HYPH |
denotes |
- |
| T1356 |
1175-1178 |
RB |
denotes |
not |
| T1357 |
1179-1182 |
IN |
denotes |
due |
| T1358 |
1183-1185 |
IN |
denotes |
to |
| T1359 |
1186-1187 |
DT |
denotes |
a |
| T1360 |
1199-1210 |
NN |
denotes |
interaction |
| T1361 |
1188-1198 |
JJ |
denotes |
homophilic |
| T1362 |
1211-1218 |
IN |
denotes |
through |
| T1363 |
1219-1222 |
PRP$ |
denotes |
its |
| T1364 |
1227-1233 |
NN |
denotes |
domain |
| T1365 |
1223-1226 |
NN |
denotes |
SAM |
| T1366 |
1234-1237 |
CC |
denotes |
but |
| T1367 |
1238-1240 |
IN |
denotes |
to |
| T1368 |
1241-1244 |
DT |
denotes |
the |
| T1369 |
1256-1262 |
NN |
denotes |
region |
| T1370 |
1245-1246 |
NN |
denotes |
C |
| T1371 |
1247-1255 |
JJ |
denotes |
terminal |
| T1372 |
1246-1247 |
HYPH |
denotes |
- |
| T1373 |
1262-1263 |
. |
denotes |
. |
| R112 |
T1128 |
T1130 |
nsubjpass |
s,conserved |
| R113 |
T1129 |
T1128 |
punct |
-,s |
| R123 |
T1140 |
T1138 |
relcl |
conserved,organisms |
| R124 |
T1141 |
T1139 |
pobj |
which,through |
| R125 |
T1142 |
T1143 |
det |
the,mechanism |
| R126 |
T1143 |
T1140 |
nsubjpass |
mechanism,conserved |
| R127 |
T1144 |
T1143 |
prep |
of,mechanism |
| R128 |
T1145 |
T1146 |
compound |
photoreceptor,development |
| R129 |
T1146 |
T1144 |
pobj |
development,of |
| R130 |
T1147 |
T1140 |
auxpass |
is,conserved |
| R131 |
T1148 |
T1140 |
advmod |
also,conserved |
| R132 |
T1149 |
T1140 |
advmod |
highly,conserved |
| R137 |
T1156 |
T1154 |
ccomp |
related,suggests |
| R138 |
T1157 |
T1158 |
det |
the,domain |
| R140 |
T1159 |
T1158 |
compound |
SAM,domain |
| R141 |
T1160 |
T1158 |
prep |
of,domain |
| R142 |
T1161 |
T1162 |
compound |
mr,s |
| R144 |
T1163 |
T1162 |
punct |
-,s |
| R145 |
T1164 |
T1156 |
auxpass |
is,related |
| R146 |
T1165 |
T1166 |
advmod |
most,closely |
| R147 |
T1166 |
T1156 |
advmod |
closely,related |
| R150 |
T1169 |
T1167 |
pobj |
ortholog,to |
| R151 |
T1170 |
T1169 |
nmod |
mouse,ortholog |
| R152 |
T1171 |
T1169 |
nmod |
polyhomeotic,ortholog |
| R153 |
T1172 |
T1173 |
punct |
(,ph |
| R154 |
T1173 |
T1171 |
parataxis |
ph,polyhomeotic |
| R155 |
T1174 |
T1173 |
punct |
),ph |
| R158 |
T1177 |
T1169 |
appos |
Rae28,ortholog |
| R159 |
T1178 |
T1177 |
punct |
/,Rae28 |
| R162 |
T1181 |
T1169 |
relcl |
known,ortholog |
| R163 |
T1182 |
T1181 |
auxpass |
is,known |
| R166 |
T1185 |
T1183 |
pobj |
molecule,as |
| R167 |
T1186 |
T1185 |
amod |
epigenetic,molecule |
| R178 |
T1199 |
T1197 |
acl |
play,possibility |
| R179 |
T1200 |
T1201 |
compound |
mr,s |
| R181 |
T1202 |
T1201 |
punct |
-,s |
| R182 |
T1203 |
T1199 |
aux |
may,play |
| R184 |
T1205 |
T1199 |
dobj |
role,play |
| R185 |
T1206 |
T1205 |
amod |
critical,role |
| R195 |
T1217 |
T1219 |
nsubjpass |
s,expressed |
| R196 |
T1218 |
T1217 |
punct |
-,s |
| R204 |
T1227 |
T1225 |
pobj |
3,at |
| R205 |
T1228 |
T1227 |
nmod |
day,3 |
| R215 |
T1238 |
T1227 |
advcl |
undergo,3 |
| R216 |
T1239 |
T1238 |
nsubj |
photoreceptors,undergo |
| R223 |
T1246 |
T1244 |
pobj |
gland,in |
| R224 |
T1247 |
T1246 |
amod |
adult,gland |
| R225 |
T1248 |
T1246 |
amod |
pineal,gland |
| R230 |
T1255 |
T1253 |
pobj |
s,of |
| R231 |
T1256 |
T1255 |
punct |
-,s |
| R236 |
T1261 |
T1259 |
pobj |
protein,by |
| R237 |
T1262 |
T1263 |
compound |
cone,rod |
| R239 |
T1264 |
T1263 |
punct |
-,rod |
| R240 |
T1265 |
T1261 |
compound |
homeodomain,protein |
| R246 |
T1273 |
T1271 |
ccomp |
associates,showed |
| R247 |
T1274 |
T1275 |
det |
the,protein |
| R248 |
T1275 |
T1273 |
nsubj |
protein,associates |
| R249 |
T1276 |
T1277 |
compound |
mr,s |
| R250 |
T1277 |
T1275 |
compound |
s,protein |
| R251 |
T1278 |
T1277 |
punct |
-,s |
| R252 |
T1279 |
T1273 |
dep |
self,associates |
| R253 |
T1280 |
T1273 |
punct |
-,associates |
| R257 |
T1284 |
T1282 |
pobj |
region,through |
| R258 |
T1285 |
T1286 |
compound |
SAM,domain |
| R259 |
T1286 |
T1287 |
npadvmod |
domain,containing |
| R261 |
T1288 |
T1287 |
punct |
-,containing |
| R263 |
T1290 |
T1284 |
cc |
as,region |
| R264 |
T1291 |
T1290 |
advmod |
well,as |
| R268 |
T1296 |
T1300 |
nsubj |
protein,localizes |
| R269 |
T1297 |
T1298 |
compound |
mr,s |
| R271 |
T1299 |
T1298 |
punct |
-,s |
| R278 |
T1307 |
T1300 |
advcl |
overexpressed,localizes |
| R279 |
T1308 |
T1309 |
compound |
mr,s |
| R281 |
T1310 |
T1309 |
punct |
-,s |
| R282 |
T1311 |
T1307 |
auxpass |
is,overexpressed |
| R291 |
T1322 |
T1320 |
pobj |
assays,in |
| R292 |
T1323 |
T1322 |
compound |
luciferase,assays |
| R296 |
T1327 |
T1318 |
ccomp |
functions,found |
| R297 |
T1328 |
T1329 |
compound |
mr,s |
| R299 |
T1330 |
T1329 |
punct |
-,s |
| R300 |
T1331 |
T1327 |
nsubj |
protein,functions |
| R301 |
T1332 |
T1331 |
acl |
fused,protein |
| R302 |
T1333 |
T1332 |
prep |
to,fused |
| R303 |
T1334 |
T1335 |
nmod |
GAL4,domain |
| R304 |
T1335 |
T1333 |
pobj |
domain,to |
| R305 |
T1336 |
T1337 |
npadvmod |
DNA,binding |
| R306 |
T1337 |
T1335 |
amod |
binding,domain |
| R307 |
T1338 |
T1337 |
punct |
-,binding |
| R310 |
T1341 |
T1339 |
pobj |
repressor,as |
| R311 |
T1342 |
T1341 |
amod |
transcriptional,repressor |
| R315 |
T1348 |
T1346 |
ccomp |
is,revealed |
| R316 |
T1349 |
T1350 |
det |
the,activity |
| R318 |
T1351 |
T1350 |
compound |
repression,activity |
| R319 |
T1352 |
T1350 |
prep |
of,activity |
| R320 |
T1353 |
T1354 |
compound |
mr,s |
| R322 |
T1355 |
T1354 |
punct |
-,s |
| R327 |
T1360 |
T1358 |
pobj |
interaction,to |
| R328 |
T1361 |
T1360 |
amod |
homophilic,interaction |
| R331 |
T1364 |
T1362 |
pobj |
domain,through |
| R332 |
T1365 |
T1364 |
compound |
SAM,domain |
| R336 |
T1369 |
T1367 |
pobj |
region,to |
| R337 |
T1370 |
T1371 |
npadvmod |
C,terminal |
| R339 |
T1372 |
T1371 |
punct |
-,terminal |
| R111 |
T1127 |
T1128 |
compound |
mr,s |
| R114 |
T1131 |
T1130 |
auxpass |
is,conserved |
| R115 |
T1132 |
T1130 |
advmod |
evolutionarily,conserved |
| R116 |
T1133 |
T1130 |
prep |
from,conserved |
| R117 |
T1134 |
T1133 |
pobj |
zebrafish,from |
| R118 |
T1135 |
T1133 |
prep |
through,from |
| R119 |
T1136 |
T1135 |
pobj |
human,through |
| R120 |
T1137 |
T1130 |
punct |
", ",conserved |
| R121 |
T1138 |
T1130 |
npadvmod |
organisms,conserved |
| R122 |
T1139 |
T1140 |
prep |
through,conserved |
| R133 |
T1150 |
T1130 |
punct |
.,conserved |
| R134 |
T1152 |
T1153 |
amod |
Phylogenetic,analysis |
| R135 |
T1153 |
T1154 |
nsubj |
analysis,suggests |
| R136 |
T1155 |
T1156 |
mark |
that,related |
| R139 |
T1158 |
T1156 |
nsubjpass |
domain,related |
| R143 |
T1162 |
T1160 |
pobj |
s,of |
| R148 |
T1167 |
T1156 |
prep |
to,related |
| R149 |
T1168 |
T1169 |
det |
a,ortholog |
| R156 |
T1175 |
T1169 |
punct |
", ",ortholog |
| R157 |
T1176 |
T1177 |
compound |
Mph1,Rae28 |
| R160 |
T1179 |
T1169 |
punct |
", ",ortholog |
| R161 |
T1180 |
T1181 |
dep |
which,known |
| R164 |
T1183 |
T1181 |
prep |
as,known |
| R165 |
T1184 |
T1185 |
det |
an,molecule |
| R168 |
T1187 |
T1185 |
acl |
involved,molecule |
| R169 |
T1188 |
T1187 |
prep |
in,involved |
| R170 |
T1189 |
T1190 |
compound |
chromatin,modifications |
| R171 |
T1190 |
T1188 |
pobj |
modifications,in |
| R172 |
T1191 |
T1154 |
punct |
.,suggests |
| R173 |
T1193 |
T1194 |
det |
These,findings |
| R174 |
T1194 |
T1195 |
nsubj |
findings,provide |
| R175 |
T1196 |
T1197 |
det |
the,possibility |
| R176 |
T1197 |
T1195 |
dobj |
possibility,provide |
| R177 |
T1198 |
T1199 |
mark |
that,play |
| R180 |
T1201 |
T1199 |
nsubj |
s,play |
| R183 |
T1204 |
T1205 |
det |
a,role |
| R186 |
T1207 |
T1199 |
prep |
by,play |
| R187 |
T1208 |
T1207 |
pcomp |
regulating,by |
| R188 |
T1209 |
T1210 |
compound |
gene,expression |
| R189 |
T1210 |
T1208 |
dobj |
expression,regulating |
| R190 |
T1211 |
T1208 |
prep |
in,regulating |
| R191 |
T1212 |
T1213 |
compound |
photoreceptor,development |
| R192 |
T1213 |
T1211 |
pobj |
development,in |
| R193 |
T1214 |
T1195 |
punct |
.,provide |
| R194 |
T1216 |
T1217 |
compound |
mr,s |
| R197 |
T1220 |
T1219 |
auxpass |
is,expressed |
| R198 |
T1221 |
T1219 |
advmod |
preferentially,expressed |
| R199 |
T1222 |
T1219 |
prep |
in,expressed |
| R200 |
T1223 |
T1224 |
det |
the,photoreceptors |
| R201 |
T1224 |
T1222 |
pobj |
photoreceptors,in |
| R202 |
T1225 |
T1219 |
prep |
at,expressed |
| R203 |
T1226 |
T1227 |
amod |
postnatal,3 |
| R206 |
T1229 |
T1230 |
punct |
–,6 |
| R207 |
T1230 |
T1227 |
prep |
6,3 |
| R208 |
T1231 |
T1232 |
punct |
(,P3 |
| R209 |
T1232 |
T1227 |
parataxis |
P3,3 |
| R210 |
T1233 |
T1234 |
punct |
-,6 |
| R211 |
T1234 |
T1232 |
prep |
6,P3 |
| R212 |
T1235 |
T1232 |
punct |
),P3 |
| R213 |
T1236 |
T1227 |
punct |
", ",3 |
| R214 |
T1237 |
T1238 |
advmod |
when,undergo |
| R217 |
T1240 |
T1241 |
amod |
terminal,differentiation |
| R218 |
T1241 |
T1238 |
dobj |
differentiation,undergo |
| R219 |
T1242 |
T1219 |
punct |
", ",expressed |
| R220 |
T1243 |
T1244 |
cc |
and,in |
| R221 |
T1244 |
T1219 |
prep |
in,expressed |
| R222 |
T1245 |
T1246 |
det |
the,gland |
| R226 |
T1249 |
T1219 |
punct |
.,expressed |
| R227 |
T1251 |
T1252 |
nsubjpass |
Transcription,regulated |
| R228 |
T1253 |
T1251 |
prep |
of,Transcription |
| R229 |
T1254 |
T1255 |
compound |
mr,s |
| R232 |
T1257 |
T1252 |
auxpass |
is,regulated |
| R233 |
T1258 |
T1252 |
advmod |
directly,regulated |
| R234 |
T1259 |
T1252 |
agent |
by,regulated |
| R235 |
T1260 |
T1261 |
det |
the,protein |
| R238 |
T1263 |
T1261 |
compound |
rod,protein |
| R241 |
T1266 |
T1261 |
appos |
Crx,protein |
| R242 |
T1267 |
T1252 |
punct |
.,regulated |
| R243 |
T1269 |
T1270 |
compound |
Immunoprecipitation,assay |
| R244 |
T1270 |
T1271 |
nsubj |
assay,showed |
| R245 |
T1272 |
T1273 |
mark |
that,associates |
| R254 |
T1281 |
T1282 |
advmod |
mainly,through |
| R255 |
T1282 |
T1273 |
prep |
through,associates |
| R256 |
T1283 |
T1284 |
det |
the,region |
| R260 |
T1287 |
T1284 |
amod |
containing,region |
| R262 |
T1289 |
T1290 |
advmod |
as,as |
| R265 |
T1292 |
T1284 |
conj |
ph,region |
| R266 |
T1293 |
T1271 |
punct |
.,showed |
| R267 |
T1295 |
T1296 |
det |
The,protein |
| R270 |
T1298 |
T1296 |
compound |
s,protein |
| R272 |
T1301 |
T1302 |
advmod |
mainly,in |
| R273 |
T1302 |
T1300 |
prep |
in,localizes |
| R274 |
T1303 |
T1304 |
det |
the,nucleus |
| R275 |
T1304 |
T1302 |
pobj |
nucleus,in |
| R276 |
T1305 |
T1300 |
punct |
", ",localizes |
| R277 |
T1306 |
T1307 |
advmod |
when,overexpressed |
| R280 |
T1309 |
T1307 |
nsubjpass |
s,overexpressed |
| R283 |
T1312 |
T1307 |
prep |
in,overexpressed |
| R284 |
T1313 |
T1314 |
compound |
HEK293T,cells |
| R285 |
T1314 |
T1312 |
pobj |
cells,in |
| R286 |
T1315 |
T1300 |
punct |
.,localizes |
| R287 |
T1317 |
T1318 |
advmod |
Moreover,found |
| R288 |
T1319 |
T1318 |
punct |
", ",found |
| R289 |
T1320 |
T1318 |
prep |
in,found |
| R290 |
T1321 |
T1322 |
det |
the,assays |
| R293 |
T1324 |
T1318 |
punct |
", ",found |
| R294 |
T1325 |
T1318 |
nsubj |
we,found |
| R295 |
T1326 |
T1327 |
mark |
that,functions |
| R298 |
T1329 |
T1331 |
compound |
s,protein |
| R308 |
T1339 |
T1327 |
prep |
as,functions |
| R309 |
T1340 |
T1341 |
det |
a,repressor |
| R312 |
T1343 |
T1318 |
punct |
.,found |
| R313 |
T1345 |
T1346 |
nsubj |
We,revealed |
| R314 |
T1347 |
T1348 |
mark |
that,is |
| R317 |
T1350 |
T1348 |
nsubj |
activity,is |
| R321 |
T1354 |
T1352 |
pobj |
s,of |
| R323 |
T1356 |
T1348 |
neg |
not,is |
| R324 |
T1357 |
T1348 |
prep |
due,is |
| R325 |
T1358 |
T1357 |
prep |
to,due |
| R326 |
T1359 |
T1360 |
det |
a,interaction |
| R329 |
T1362 |
T1360 |
prep |
through,interaction |
| R330 |
T1363 |
T1364 |
poss |
its,domain |
| R333 |
T1366 |
T1358 |
cc |
but,to |
| R334 |
T1367 |
T1358 |
conj |
to,to |
| R335 |
T1368 |
T1369 |
det |
the,region |
| R338 |
T1371 |
T1369 |
amod |
terminal,region |
| R340 |
T1373 |
T1346 |
punct |
.,revealed |