Id |
Subject |
Object |
Predicate |
Lexical cue |
T13284 |
924-925 |
-RRB- |
denotes |
) |
T13285 |
925-926 |
. |
denotes |
. |
T31407 |
11-14 |
DT |
denotes |
The |
T31408 |
20-27 |
NN |
denotes |
protein |
T31409 |
15-17 |
NN |
denotes |
mr |
T31410 |
18-19 |
NN |
denotes |
s |
T31411 |
17-18 |
HYPH |
denotes |
- |
T31412 |
37-46 |
VB |
denotes |
associate |
T31413 |
28-31 |
MD |
denotes |
can |
T31414 |
32-36 |
NN |
denotes |
self |
T31415 |
36-37 |
HYPH |
denotes |
- |
T31416 |
47-49 |
IN |
denotes |
in |
T31417 |
50-59 |
JJ |
denotes |
mammalian |
T31418 |
60-65 |
NNS |
denotes |
cells |
T31419 |
65-66 |
. |
denotes |
. |
T31420 |
66-142 |
sentence |
denotes |
(A) Schematic drawing of the constructs used for immunoprecipitation assay. |
T31421 |
67-68 |
-LRB- |
denotes |
( |
T31422 |
68-69 |
LS |
denotes |
A |
T31423 |
81-88 |
NN |
denotes |
drawing |
T31424 |
69-70 |
-RRB- |
denotes |
) |
T31425 |
71-80 |
JJ |
denotes |
Schematic |
T31426 |
89-91 |
IN |
denotes |
of |
T31427 |
92-95 |
DT |
denotes |
the |
T31428 |
96-106 |
NNS |
denotes |
constructs |
T31429 |
107-111 |
VBN |
denotes |
used |
T31430 |
112-115 |
IN |
denotes |
for |
T31431 |
116-135 |
NN |
denotes |
immunoprecipitation |
T31432 |
136-141 |
NN |
denotes |
assay |
T31433 |
141-142 |
. |
denotes |
. |
T31434 |
142-320 |
sentence |
denotes |
HA-tagged or Flag-tagged full-length (amino acids 1 to 542), ΔSAM (amino acids 1 to 400) and SAM (amino acids 401 to 542) regions were inserted into pcDNA3 vector, respectively. |
T31435 |
143-145 |
NN |
denotes |
HA |
T31436 |
146-152 |
VBN |
denotes |
tagged |
T31437 |
145-146 |
HYPH |
denotes |
- |
T31438 |
265-272 |
NNS |
denotes |
regions |
T31439 |
153-155 |
CC |
denotes |
or |
T31440 |
156-160 |
NN |
denotes |
Flag |
T31441 |
161-167 |
VBN |
denotes |
tagged |
T31442 |
160-161 |
HYPH |
denotes |
- |
T31443 |
168-172 |
JJ |
denotes |
full |
T31444 |
173-179 |
NN |
denotes |
length |
T31445 |
172-173 |
HYPH |
denotes |
- |
T31446 |
180-181 |
-LRB- |
denotes |
( |
T31447 |
193-194 |
CD |
denotes |
1 |
T31448 |
181-186 |
NN |
denotes |
amino |
T31449 |
187-192 |
NNS |
denotes |
acids |
T31450 |
195-197 |
IN |
denotes |
to |
T31451 |
198-201 |
CD |
denotes |
542 |
T31452 |
201-202 |
-RRB- |
denotes |
) |
T31453 |
202-204 |
, |
denotes |
, |
T31454 |
204-208 |
NN |
denotes |
ΔSAM |
T31455 |
209-210 |
-LRB- |
denotes |
( |
T31456 |
222-223 |
CD |
denotes |
1 |
T31457 |
210-215 |
NN |
denotes |
amino |
T31458 |
216-221 |
NNS |
denotes |
acids |
T31459 |
224-226 |
IN |
denotes |
to |
T31460 |
227-230 |
CD |
denotes |
400 |
T31461 |
230-231 |
-RRB- |
denotes |
) |
T31462 |
232-235 |
CC |
denotes |
and |
T31463 |
236-239 |
NN |
denotes |
SAM |
T31464 |
240-241 |
-LRB- |
denotes |
( |
T31465 |
253-256 |
CD |
denotes |
401 |
T31466 |
241-246 |
NN |
denotes |
amino |
T31467 |
247-252 |
NNS |
denotes |
acids |
T31468 |
257-259 |
IN |
denotes |
to |
T31469 |
260-263 |
CD |
denotes |
542 |
T31470 |
263-264 |
-RRB- |
denotes |
) |
T31471 |
278-286 |
VBN |
denotes |
inserted |
T31472 |
273-277 |
VBD |
denotes |
were |
T31473 |
287-291 |
IN |
denotes |
into |
T31474 |
292-298 |
NN |
denotes |
pcDNA3 |
T31475 |
299-305 |
NN |
denotes |
vector |
T31476 |
305-307 |
, |
denotes |
, |
T31477 |
307-319 |
RB |
denotes |
respectively |
T31478 |
319-320 |
. |
denotes |
. |
T31479 |
320-392 |
sentence |
denotes |
(B) The constructs indicated above were transfected into HEK293T cells. |
T31480 |
321-322 |
-LRB- |
denotes |
( |
T31481 |
322-323 |
LS |
denotes |
B |
T31482 |
361-372 |
VBN |
denotes |
transfected |
T31483 |
323-324 |
-RRB- |
denotes |
) |
T31484 |
325-328 |
DT |
denotes |
The |
T31485 |
329-339 |
NNS |
denotes |
constructs |
T31486 |
340-349 |
VBN |
denotes |
indicated |
T31487 |
350-355 |
RB |
denotes |
above |
T31488 |
356-360 |
VBD |
denotes |
were |
T31489 |
373-377 |
IN |
denotes |
into |
T31490 |
378-385 |
NN |
denotes |
HEK293T |
T31491 |
386-391 |
NNS |
denotes |
cells |
T31492 |
391-392 |
. |
denotes |
. |
T31493 |
392-484 |
sentence |
denotes |
Each lane was co-immunoprecipitated by anti-Flag antibody and detected by anti-HA antibody. |
T31494 |
393-397 |
DT |
denotes |
Each |
T31495 |
398-402 |
NN |
denotes |
lane |
T31496 |
407-428 |
VBN |
denotes |
co-immunoprecipitated |
T31497 |
403-406 |
VBD |
denotes |
was |
T31498 |
429-431 |
IN |
denotes |
by |
T31499 |
432-441 |
JJ |
denotes |
anti-Flag |
T31500 |
442-450 |
NN |
denotes |
antibody |
T31501 |
451-454 |
CC |
denotes |
and |
T31502 |
455-463 |
VBN |
denotes |
detected |
T31503 |
464-466 |
IN |
denotes |
by |
T31504 |
467-474 |
JJ |
denotes |
anti-HA |
T31505 |
475-483 |
NN |
denotes |
antibody |
T31506 |
483-484 |
. |
denotes |
. |
T31507 |
484-537 |
sentence |
denotes |
Input protein lysates are shown in the lower panels. |
T31508 |
485-490 |
NN |
denotes |
Input |
T31509 |
499-506 |
NNS |
denotes |
lysates |
T31510 |
491-498 |
NN |
denotes |
protein |
T31511 |
511-516 |
VBN |
denotes |
shown |
T31512 |
507-510 |
VBP |
denotes |
are |
T31513 |
517-519 |
IN |
denotes |
in |
T31514 |
520-523 |
DT |
denotes |
the |
T31515 |
530-536 |
NNS |
denotes |
panels |
T31516 |
524-529 |
JJ |
denotes |
lower |
T31517 |
536-537 |
. |
denotes |
. |
T31518 |
537-659 |
sentence |
denotes |
(C) Flag-tagged two site-directed mr-s mutants, Flag-W404A and Flag-G453A were generated and co-transfected with full-HA. |
T31519 |
538-539 |
-LRB- |
denotes |
( |
T31520 |
539-540 |
LS |
denotes |
C |
T31521 |
617-626 |
VBN |
denotes |
generated |
T31522 |
540-541 |
-RRB- |
denotes |
) |
T31523 |
542-546 |
NN |
denotes |
Flag |
T31524 |
547-553 |
VBN |
denotes |
tagged |
T31525 |
546-547 |
HYPH |
denotes |
- |
T31526 |
577-584 |
NNS |
denotes |
mutants |
T31527 |
554-557 |
CD |
denotes |
two |
T31528 |
558-562 |
NN |
denotes |
site |
T31529 |
563-571 |
VBN |
denotes |
directed |
T31530 |
562-563 |
HYPH |
denotes |
- |
T31531 |
572-574 |
NN |
denotes |
mr |
T31532 |
575-576 |
NN |
denotes |
s |
T31533 |
574-575 |
HYPH |
denotes |
- |
T31534 |
584-586 |
, |
denotes |
, |
T31535 |
586-590 |
NN |
denotes |
Flag |
T31536 |
591-596 |
NN |
denotes |
W404A |
T31537 |
590-591 |
HYPH |
denotes |
- |
T31538 |
597-600 |
CC |
denotes |
and |
T31539 |
601-605 |
NN |
denotes |
Flag |
T31540 |
606-611 |
NN |
denotes |
G453A |
T31541 |
605-606 |
HYPH |
denotes |
- |
T31542 |
612-616 |
VBD |
denotes |
were |
T31543 |
627-630 |
CC |
denotes |
and |
T31544 |
631-645 |
VBN |
denotes |
co-transfected |
T31545 |
646-650 |
IN |
denotes |
with |
T31546 |
651-655 |
JJ |
denotes |
full |
T31547 |
656-658 |
NN |
denotes |
HA |
T31548 |
655-656 |
HYPH |
denotes |
- |
T31549 |
658-659 |
. |
denotes |
. |
T31550 |
659-751 |
sentence |
denotes |
Each lane was co-immunoprecipitated by anti-HA antibody and detected by anti-Flag antibody. |
T31551 |
660-664 |
DT |
denotes |
Each |
T31552 |
665-669 |
NN |
denotes |
lane |
T31553 |
674-695 |
VBN |
denotes |
co-immunoprecipitated |
T31554 |
670-673 |
VBD |
denotes |
was |
T31555 |
696-698 |
IN |
denotes |
by |
T31556 |
699-706 |
JJ |
denotes |
anti-HA |
T31557 |
707-715 |
NN |
denotes |
antibody |
T31558 |
716-719 |
CC |
denotes |
and |
T31559 |
720-728 |
VBN |
denotes |
detected |
T31560 |
729-731 |
IN |
denotes |
by |
T31561 |
732-741 |
JJ |
denotes |
anti-Flag |
T31562 |
742-750 |
NN |
denotes |
antibody |
T31563 |
750-751 |
. |
denotes |
. |
T13281 |
909-913 |
NN |
denotes |
Fig. |
T13282 |
914-916 |
NN |
denotes |
1B |
T13283 |
916-918 |
, |
denotes |
, |
T13246 |
0-926 |
sentence |
denotes |
Figure 5 The mr-s protein can self-associate in mammalian cells. (A) Schematic drawing of the constructs used for immunoprecipitation assay. HA-tagged or Flag-tagged full-length (amino acids 1 to 542), ΔSAM (amino acids 1 to 400) and SAM (amino acids 401 to 542) regions were inserted into pcDNA3 vector, respectively. (B) The constructs indicated above were transfected into HEK293T cells. Each lane was co-immunoprecipitated by anti-Flag antibody and detected by anti-HA antibody. Input protein lysates are shown in the lower panels. (C) Flag-tagged two site-directed mr-s mutants, Flag-W404A and Flag-G453A were generated and co-transfected with full-HA. Each lane was co-immunoprecipitated by anti-HA antibody and detected by anti-Flag antibody. To investigate whether the mr-s protein self-associates mainly through the SAM domain, two site-directed mutations were generated in the SAM domain of mr-s (Fig. 1B, arrows). |
T13247 |
752-754 |
TO |
denotes |
To |
T13248 |
755-766 |
VB |
denotes |
investigate |
T13249 |
872-881 |
VBN |
denotes |
generated |
T13250 |
767-774 |
IN |
denotes |
whether |
T13251 |
797-807 |
VBZ |
denotes |
associates |
T13252 |
775-778 |
DT |
denotes |
the |
T13253 |
784-791 |
NN |
denotes |
protein |
T13254 |
779-781 |
NN |
denotes |
mr |
T13255 |
782-783 |
NN |
denotes |
s |
T13256 |
781-782 |
HYPH |
denotes |
- |
T13257 |
792-796 |
NN |
denotes |
self |
T13258 |
796-797 |
HYPH |
denotes |
- |
T13259 |
808-814 |
RB |
denotes |
mainly |
T13260 |
815-822 |
IN |
denotes |
through |
T13261 |
823-826 |
DT |
denotes |
the |
T13262 |
831-837 |
NN |
denotes |
domain |
T13263 |
827-830 |
NN |
denotes |
SAM |
T13264 |
837-839 |
, |
denotes |
, |
T13265 |
839-842 |
CD |
denotes |
two |
T13266 |
857-866 |
NNS |
denotes |
mutations |
T13267 |
843-847 |
NN |
denotes |
site |
T13268 |
848-856 |
VBN |
denotes |
directed |
T13269 |
847-848 |
HYPH |
denotes |
- |
T13270 |
867-871 |
VBD |
denotes |
were |
T13271 |
882-884 |
IN |
denotes |
in |
T13272 |
885-888 |
DT |
denotes |
the |
T13273 |
893-899 |
NN |
denotes |
domain |
T13274 |
889-892 |
NN |
denotes |
SAM |
T13275 |
900-902 |
IN |
denotes |
of |
T13276 |
903-905 |
NN |
denotes |
mr |
T13277 |
906-907 |
NN |
denotes |
s |
T13278 |
905-906 |
HYPH |
denotes |
- |
T13279 |
908-909 |
-LRB- |
denotes |
( |
T13280 |
918-924 |
NNS |
denotes |
arrows |
R3591 |
T13277 |
T13275 |
pobj |
s,of |
R3593 |
T13278 |
T13277 |
punct |
-,s |
R3594 |
T13279 |
T13280 |
punct |
(,arrows |
R3595 |
T13280 |
T13249 |
parataxis |
arrows,generated |
R3596 |
T13281 |
T13282 |
compound |
Fig.,1B |
R3597 |
T13282 |
T13280 |
dep |
1B,arrows |
R3599 |
T13283 |
T13280 |
punct |
", ",arrows |
R3602 |
T13284 |
T13280 |
punct |
),arrows |
R3604 |
T13285 |
T13249 |
punct |
.,generated |
R8967 |
T31407 |
T31408 |
det |
The,protein |
R8968 |
T31408 |
T31412 |
nsubj |
protein,associate |
R8969 |
T31409 |
T31410 |
compound |
mr,s |
R8970 |
T31410 |
T31408 |
compound |
s,protein |
R8971 |
T31411 |
T31410 |
punct |
-,s |
R8972 |
T31413 |
T31412 |
aux |
can,associate |
R8973 |
T31414 |
T31412 |
dep |
self,associate |
R8974 |
T31415 |
T31412 |
punct |
-,associate |
R8975 |
T31416 |
T31412 |
prep |
in,associate |
R8976 |
T31417 |
T31418 |
amod |
mammalian,cells |
R8977 |
T31418 |
T31416 |
pobj |
cells,in |
R8978 |
T31419 |
T31412 |
punct |
.,associate |
R8979 |
T31421 |
T31422 |
punct |
(,A |
R8980 |
T31422 |
T31423 |
meta |
A,drawing |
R8981 |
T31424 |
T31422 |
punct |
),A |
R8982 |
T31425 |
T31423 |
amod |
Schematic,drawing |
R8983 |
T31426 |
T31423 |
prep |
of,drawing |
R8984 |
T31427 |
T31428 |
det |
the,constructs |
R8985 |
T31428 |
T31426 |
pobj |
constructs,of |
R8986 |
T31429 |
T31428 |
acl |
used,constructs |
R8987 |
T31430 |
T31429 |
prep |
for,used |
R8988 |
T31431 |
T31432 |
compound |
immunoprecipitation,assay |
R8989 |
T31432 |
T31430 |
pobj |
assay,for |
R8990 |
T31433 |
T31423 |
punct |
.,drawing |
R8991 |
T31435 |
T31436 |
npadvmod |
HA,tagged |
R8992 |
T31436 |
T31438 |
amod |
tagged,regions |
R8993 |
T31437 |
T31436 |
punct |
-,tagged |
R8994 |
T31438 |
T31471 |
nsubjpass |
regions,inserted |
R8995 |
T31439 |
T31436 |
cc |
or,tagged |
R8996 |
T31440 |
T31441 |
npadvmod |
Flag,tagged |
R8997 |
T31441 |
T31436 |
conj |
tagged,tagged |
R8998 |
T31442 |
T31441 |
punct |
-,tagged |
R8999 |
T31443 |
T31444 |
amod |
full,length |
R9000 |
T31444 |
T31438 |
nmod |
length,regions |
R9001 |
T31445 |
T31444 |
punct |
-,length |
R9002 |
T31446 |
T31447 |
punct |
(,1 |
R9003 |
T31447 |
T31444 |
parataxis |
1,length |
R9004 |
T31448 |
T31447 |
nmod |
amino,1 |
R9005 |
T31449 |
T31447 |
nmod |
acids,1 |
R9006 |
T31450 |
T31447 |
prep |
to,1 |
R9007 |
T31451 |
T31450 |
pobj |
542,to |
R9008 |
T31452 |
T31447 |
punct |
),1 |
R9009 |
T31453 |
T31438 |
punct |
", ",regions |
R9010 |
T31454 |
T31438 |
nmod |
ΔSAM,regions |
R9011 |
T31455 |
T31456 |
punct |
(,1 |
R9012 |
T31456 |
T31454 |
parataxis |
1,ΔSAM |
R9013 |
T31457 |
T31456 |
nmod |
amino,1 |
R9014 |
T31458 |
T31456 |
nmod |
acids,1 |
R9015 |
T31459 |
T31456 |
prep |
to,1 |
R9016 |
T31460 |
T31459 |
pobj |
400,to |
R9017 |
T31461 |
T31456 |
punct |
),1 |
R9018 |
T31462 |
T31454 |
cc |
and,ΔSAM |
R9019 |
T31463 |
T31454 |
conj |
SAM,ΔSAM |
R9020 |
T31464 |
T31465 |
punct |
(,401 |
R9021 |
T31465 |
T31463 |
parataxis |
401,SAM |
R9022 |
T31466 |
T31465 |
nmod |
amino,401 |
R9023 |
T31467 |
T31465 |
nmod |
acids,401 |
R9024 |
T31468 |
T31465 |
prep |
to,401 |
R9025 |
T31469 |
T31468 |
pobj |
542,to |
R9026 |
T31470 |
T31465 |
punct |
),401 |
R9027 |
T31472 |
T31471 |
auxpass |
were,inserted |
R9028 |
T31473 |
T31471 |
prep |
into,inserted |
R9029 |
T31474 |
T31475 |
compound |
pcDNA3,vector |
R9030 |
T31475 |
T31473 |
pobj |
vector,into |
R9031 |
T31476 |
T31471 |
punct |
", ",inserted |
R9032 |
T31477 |
T31471 |
advmod |
respectively,inserted |
R9033 |
T31478 |
T31471 |
punct |
.,inserted |
R9034 |
T31480 |
T31481 |
punct |
(,B |
R9035 |
T31481 |
T31482 |
meta |
B,transfected |
R9036 |
T31483 |
T31481 |
punct |
),B |
R9037 |
T31484 |
T31485 |
det |
The,constructs |
R9038 |
T31485 |
T31482 |
nsubjpass |
constructs,transfected |
R9039 |
T31486 |
T31485 |
acl |
indicated,constructs |
R9040 |
T31487 |
T31486 |
advmod |
above,indicated |
R9041 |
T31488 |
T31482 |
auxpass |
were,transfected |
R9042 |
T31489 |
T31482 |
prep |
into,transfected |
R9043 |
T31490 |
T31491 |
compound |
HEK293T,cells |
R9044 |
T31491 |
T31489 |
pobj |
cells,into |
R9045 |
T31492 |
T31482 |
punct |
.,transfected |
R9046 |
T31494 |
T31495 |
det |
Each,lane |
R9047 |
T31495 |
T31496 |
nsubjpass |
lane,co-immunoprecipitated |
R9048 |
T31497 |
T31496 |
auxpass |
was,co-immunoprecipitated |
R9049 |
T31498 |
T31496 |
agent |
by,co-immunoprecipitated |
R9050 |
T31499 |
T31500 |
amod |
anti-Flag,antibody |
R9051 |
T31500 |
T31498 |
pobj |
antibody,by |
R9052 |
T31501 |
T31496 |
cc |
and,co-immunoprecipitated |
R9053 |
T31502 |
T31496 |
conj |
detected,co-immunoprecipitated |
R9054 |
T31503 |
T31502 |
agent |
by,detected |
R9055 |
T31504 |
T31505 |
amod |
anti-HA,antibody |
R9056 |
T31505 |
T31503 |
pobj |
antibody,by |
R9057 |
T31506 |
T31496 |
punct |
.,co-immunoprecipitated |
R9058 |
T31508 |
T31509 |
compound |
Input,lysates |
R9059 |
T31509 |
T31511 |
nsubjpass |
lysates,shown |
R9060 |
T31510 |
T31509 |
compound |
protein,lysates |
R9061 |
T31512 |
T31511 |
auxpass |
are,shown |
R9062 |
T31513 |
T31511 |
prep |
in,shown |
R9063 |
T31514 |
T31515 |
det |
the,panels |
R9064 |
T31515 |
T31513 |
pobj |
panels,in |
R9065 |
T31516 |
T31515 |
amod |
lower,panels |
R9066 |
T31517 |
T31511 |
punct |
.,shown |
R9067 |
T31519 |
T31520 |
punct |
(,C |
R9068 |
T31520 |
T31521 |
meta |
C,generated |
R9069 |
T31522 |
T31520 |
punct |
),C |
R9070 |
T31523 |
T31524 |
npadvmod |
Flag,tagged |
R9071 |
T31524 |
T31526 |
amod |
tagged,mutants |
R9072 |
T31525 |
T31524 |
punct |
-,tagged |
R9073 |
T31526 |
T31521 |
nsubjpass |
mutants,generated |
R9074 |
T31527 |
T31528 |
nummod |
two,site |
R9075 |
T31528 |
T31529 |
npadvmod |
site,directed |
R9076 |
T31529 |
T31526 |
amod |
directed,mutants |
R9077 |
T31530 |
T31529 |
punct |
-,directed |
R9078 |
T31531 |
T31532 |
compound |
mr,s |
R9079 |
T31532 |
T31526 |
compound |
s,mutants |
R9080 |
T31533 |
T31532 |
punct |
-,s |
R9081 |
T31534 |
T31526 |
punct |
", ",mutants |
R9082 |
T31535 |
T31536 |
compound |
Flag,W404A |
R9083 |
T31536 |
T31526 |
appos |
W404A,mutants |
R9084 |
T31537 |
T31536 |
punct |
-,W404A |
R9085 |
T31538 |
T31536 |
cc |
and,W404A |
R9086 |
T31539 |
T31540 |
compound |
Flag,G453A |
R9087 |
T31540 |
T31536 |
conj |
G453A,W404A |
R9088 |
T31541 |
T31540 |
punct |
-,G453A |
R9089 |
T31542 |
T31521 |
auxpass |
were,generated |
R9090 |
T31543 |
T31521 |
cc |
and,generated |
R9091 |
T31544 |
T31521 |
conj |
co-transfected,generated |
R9092 |
T31545 |
T31544 |
prep |
with,co-transfected |
R9093 |
T31546 |
T31547 |
amod |
full,HA |
R9094 |
T31547 |
T31545 |
pobj |
HA,with |
R9095 |
T31548 |
T31547 |
punct |
-,HA |
R9096 |
T31549 |
T31521 |
punct |
.,generated |
R9097 |
T31551 |
T31552 |
det |
Each,lane |
R9098 |
T31552 |
T31553 |
nsubjpass |
lane,co-immunoprecipitated |
R9099 |
T31554 |
T31553 |
auxpass |
was,co-immunoprecipitated |
R9100 |
T31555 |
T31553 |
agent |
by,co-immunoprecipitated |
R9101 |
T31556 |
T31557 |
amod |
anti-HA,antibody |
R9102 |
T31557 |
T31555 |
pobj |
antibody,by |
R9103 |
T31558 |
T31553 |
cc |
and,co-immunoprecipitated |
R9104 |
T31559 |
T31553 |
conj |
detected,co-immunoprecipitated |
R9105 |
T31560 |
T31559 |
agent |
by,detected |
R9106 |
T31561 |
T31562 |
amod |
anti-Flag,antibody |
R9107 |
T31562 |
T31560 |
pobj |
antibody,by |
R9108 |
T31563 |
T31553 |
punct |
.,co-immunoprecipitated |
R3549 |
T13247 |
T13248 |
aux |
To,investigate |
R3551 |
T13248 |
T13249 |
advcl |
investigate,generated |
R3553 |
T13250 |
T13251 |
mark |
whether,associates |
R3554 |
T13251 |
T13248 |
ccomp |
associates,investigate |
R3556 |
T13252 |
T13253 |
det |
the,protein |
R3557 |
T13253 |
T13251 |
nsubj |
protein,associates |
R3558 |
T13254 |
T13255 |
compound |
mr,s |
R3560 |
T13255 |
T13253 |
compound |
s,protein |
R3561 |
T13256 |
T13255 |
punct |
-,s |
R3563 |
T13257 |
T13251 |
dep |
self,associates |
R3564 |
T13258 |
T13251 |
punct |
-,associates |
R3565 |
T13259 |
T13251 |
advmod |
mainly,associates |
R3567 |
T13260 |
T13251 |
prep |
through,associates |
R3568 |
T13261 |
T13262 |
det |
the,domain |
R3569 |
T13262 |
T13260 |
pobj |
domain,through |
R3571 |
T13263 |
T13262 |
compound |
SAM,domain |
R3572 |
T13264 |
T13249 |
punct |
", ",generated |
R3574 |
T13265 |
T13266 |
nummod |
two,mutations |
R3575 |
T13266 |
T13249 |
nsubjpass |
mutations,generated |
R3576 |
T13267 |
T13268 |
npadvmod |
site,directed |
R3578 |
T13268 |
T13266 |
amod |
directed,mutations |
R3579 |
T13269 |
T13268 |
punct |
-,directed |
R3580 |
T13270 |
T13249 |
auxpass |
were,generated |
R3582 |
T13271 |
T13249 |
prep |
in,generated |
R3583 |
T13272 |
T13273 |
det |
the,domain |
R3584 |
T13273 |
T13271 |
pobj |
domain,in |
R3586 |
T13274 |
T13273 |
compound |
SAM,domain |
R3587 |
T13275 |
T13273 |
prep |
of,domain |
R3588 |
T13276 |
T13277 |
compound |
mr,s |