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PMC:1435744 / 17623-18265 JSONTXT

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craft-ca-core-ex-dev

Below, discontinuous spans are shown in the bag model. You can change it to the chain model.

Id Subject Object Predicate Lexical cue
T9690 29-36 SO_EXT:0000440 denotes vectors
T9691 46-55 SO_EXT:sequence_alteration_entity_or_process denotes mutations
T9692 85-88 PR_EXT:000005904 denotes Crx
T9693 89-96 CHEMINF_GO_EXT:chemical_binding_or_bond_formation denotes binding
T9694 89-102 SO_EXT:0000409 denotes binding sites
T9695 137-140 SO_EXT:sequence_altered_entity_or_alteration_process denotes mut
T9696 156-159 PR_EXT:000005904 denotes Crx
T9697 160-170 GO:0010467 denotes expression
T9698 171-177 SO_EXT:0000440 denotes vector
T9699 228-231 SO_EXT:sequence_altered_entity_or_alteration_process denotes mut
T9700 292-295 PR_EXT:000005904 denotes Crx
T9701 395-406 GO:0009294 denotes transfected
T9702 440-443 PR_EXT:000005904 denotes Crx
T9703 492-495 PR_EXT:000005904 denotes Crx
T9704 496-503 CHEMINF_GO_EXT:chemical_binding_or_bond_formation denotes binding
T9705 496-509 SO_EXT:0000409 denotes binding sites
T9706 513-515 SO_EXT:0000028 denotes bp
T9707 524-526 SO_EXT:0000028 denotes bp
T9708 527-535 SO_EXT:sequence_upstreamness denotes upstream
T9709 545-558 GO_EXT:transcription denotes transcription
T9710 545-574 SO_EXT:0000315 denotes transcription initiation site
T9711 602-612 GO:0065007 denotes regulation
T9712 616-620 PR_EXT:000014441 denotes mr-s
T9713 621-634 GO_EXT:transcription denotes transcription
T9714 638-641 PR_EXT:000005904 denotes Crx

craft-ca-core-dev

Below, discontinuous spans are shown in the bag model. You can change it to the chain model.

Id Subject Object Predicate Lexical cue
T9515 29-36 SO:0000440 denotes vectors
T9516 85-88 PR:000005904 denotes Crx
T9517 89-102 SO:0000409 denotes binding sites
T9518 156-159 PR:000005904 denotes Crx
T9519 160-170 GO:0010467 denotes expression
T9520 171-177 SO:0000440 denotes vector
T9521 292-295 PR:000005904 denotes Crx
T9522 395-406 GO:0009294 denotes transfected
T9523 440-443 PR:000005904 denotes Crx
T9524 492-495 PR:000005904 denotes Crx
T9525 496-509 SO:0000409 denotes binding sites
T9526 513-515 SO:0000028 denotes bp
T9527 524-526 SO:0000028 denotes bp
T9528 545-574 SO:0000315 denotes transcription initiation site
T9529 602-612 GO:0065007 denotes regulation
T9530 616-620 PR:000014441 denotes mr-s
T9531 638-641 PR:000005904 denotes Crx

craft-sa-dev

Id Subject Object Predicate Lexical cue
T10302 0-2 PRP denotes We
T10303 8-19 VBD denotes constructed
T10304 3-7 RB denotes also
T10305 20-28 NN denotes reporter
T10306 29-36 NNS denotes vectors
T10307 37-39 IN denotes in
T10308 61-71 VBN denotes introduced
T10309 40-45 WDT denotes which
T10310 46-55 NNS denotes mutations
T10311 56-60 VBD denotes were
T10312 72-74 IN denotes at
T10313 75-78 DT denotes the
T10314 97-102 NNS denotes sites
T10315 79-84 CD denotes three
T10316 85-88 NN denotes Crx
T10317 89-96 NN denotes binding
T10318 103-104 -LRB- denotes (
T10319 113-120 NN denotes mut1259
T10320 104-108 NN denotes Fig.
T10321 109-111 NN denotes 3D
T10322 111-113 , denotes ,
T10323 120-122 , denotes ,
T10324 122-128 NN denotes mut198
T10325 128-130 , denotes ,
T10326 130-135 NN denotes mut72
T10327 135-137 , denotes ,
T10328 137-140 NN denotes mut
T10329 141-144 NN denotes all
T10330 144-145 -RRB- denotes )
T10331 145-146 . denotes .
T10332 146-260 sentence denotes Then the Crx expression vector was co-introduced with mut1259, mut198, mut72 and mut all, respectively (Fig. 3F).
T10333 147-151 RB denotes Then
T10334 182-195 VBN denotes co-introduced
T10335 152-155 DT denotes the
T10336 171-177 NN denotes vector
T10337 156-159 NN denotes Crx
T10338 160-170 NN denotes expression
T10339 178-181 VBD denotes was
T10340 196-200 IN denotes with
T10341 201-208 NN denotes mut1259
T10342 208-210 , denotes ,
T10343 210-216 NN denotes mut198
T10344 216-218 , denotes ,
T10345 218-223 NN denotes mut72
T10346 224-227 CC denotes and
T10347 228-231 NN denotes mut
T10348 232-235 NN denotes all
T10349 235-237 , denotes ,
T10350 237-249 RB denotes respectively
T10351 250-251 -LRB- denotes (
T10352 256-258 NN denotes 3F
T10353 251-255 NN denotes Fig.
T10354 258-259 -RRB- denotes )
T10355 259-260 . denotes .
T10356 260-355 sentence denotes The transactivaton activity by Crx was clearly reduced when mut198 or mut72 was co-introduced.
T10357 261-264 DT denotes The
T10358 280-288 NN denotes activity
T10359 265-279 NN denotes transactivaton
T10360 308-315 VBN denotes reduced
T10361 289-291 IN denotes by
T10362 292-295 NN denotes Crx
T10363 296-299 VBD denotes was
T10364 300-307 RB denotes clearly
T10365 316-320 WRB denotes when
T10366 341-354 VBN denotes co-introduced
T10367 321-327 NN denotes mut198
T10368 328-330 CC denotes or
T10369 331-336 NN denotes mut72
T10370 337-340 VBD denotes was
T10371 354-355 . denotes .
T10372 355-460 sentence denotes On the other hand, when mut1259 was co-transfected, the transactivation activity by Crx was not altered.
T10373 356-358 IN denotes On
T10374 452-459 VBN denotes altered
T10375 359-362 DT denotes the
T10376 369-373 NN denotes hand
T10377 363-368 JJ denotes other
T10378 373-375 , denotes ,
T10379 375-379 WRB denotes when
T10380 392-406 VBN denotes co-transfected
T10381 380-387 NN denotes mut1259
T10382 388-391 VBD denotes was
T10383 406-408 , denotes ,
T10384 408-411 DT denotes the
T10385 428-436 NN denotes activity
T10386 412-427 NN denotes transactivation
T10387 437-439 IN denotes by
T10388 440-443 NN denotes Crx
T10389 444-447 VBD denotes was
T10390 448-451 RB denotes not
T10391 459-460 . denotes .
T10392 460-642 sentence denotes These results suggest that the Crx binding sites 72-bp and 198-bp upstream from the transcription initiation site are crucial for the direct regulation of mr-s transcription by Crx.
T10393 461-466 DT denotes These
T10394 467-474 NNS denotes results
T10395 475-482 VBP denotes suggest
T10396 483-487 IN denotes that
T10397 575-578 VBP denotes are
T10398 488-491 DT denotes the
T10399 504-509 NNS denotes sites
T10400 492-495 NN denotes Crx
T10401 496-503 NN denotes binding
T10402 510-512 CD denotes 72
T10403 513-515 NN denotes bp
T10404 512-513 HYPH denotes -
T10405 527-535 RB denotes upstream
T10406 516-519 CC denotes and
T10407 520-523 CD denotes 198
T10408 524-526 NN denotes bp
T10409 523-524 HYPH denotes -
T10410 536-540 IN denotes from
T10411 541-544 DT denotes the
T10412 570-574 NN denotes site
T10413 545-558 NN denotes transcription
T10414 559-569 NN denotes initiation
T10415 579-586 JJ denotes crucial
T10416 587-590 IN denotes for
T10417 591-594 DT denotes the
T10418 602-612 NN denotes regulation
T10419 595-601 JJ denotes direct
T10420 613-615 IN denotes of
T10421 616-618 NN denotes mr
T10422 619-620 NN denotes s
T10423 618-619 HYPH denotes -
T10424 621-634 NN denotes transcription
T10425 635-637 IN denotes by
T10426 638-641 NN denotes Crx
T10427 641-642 . denotes .
R2750 T10302 T10303 nsubj We,constructed
R2751 T10304 T10303 advmod also,constructed
R2752 T10305 T10306 compound reporter,vectors
R2753 T10306 T10303 dobj vectors,constructed
R2754 T10307 T10308 prep in,introduced
R2755 T10308 T10306 relcl introduced,vectors
R2756 T10309 T10307 pobj which,in
R2757 T10310 T10308 nsubjpass mutations,introduced
R2758 T10311 T10308 auxpass were,introduced
R2759 T10312 T10308 prep at,introduced
R2760 T10313 T10314 det the,sites
R2761 T10314 T10312 pobj sites,at
R2762 T10315 T10314 nummod three,sites
R2763 T10316 T10317 compound Crx,binding
R2764 T10317 T10314 compound binding,sites
R2765 T10318 T10319 punct (,mut1259
R2766 T10319 T10303 parataxis mut1259,constructed
R2767 T10320 T10321 compound Fig.,3D
R2768 T10321 T10319 dep 3D,mut1259
R2769 T10322 T10319 punct ", ",mut1259
R2770 T10323 T10319 punct ", ",mut1259
R2771 T10324 T10319 appos mut198,mut1259
R2772 T10325 T10319 punct ", ",mut1259
R2773 T10326 T10319 appos mut72,mut1259
R2774 T10327 T10319 punct ", ",mut1259
R2775 T10328 T10329 compound mut,all
R2776 T10329 T10319 appos all,mut1259
R2777 T10330 T10319 punct ),mut1259
R2778 T10331 T10303 punct .,constructed
R2779 T10333 T10334 advmod Then,co-introduced
R2780 T10335 T10336 det the,vector
R2781 T10336 T10334 nsubjpass vector,co-introduced
R2782 T10337 T10336 compound Crx,vector
R2783 T10338 T10336 compound expression,vector
R2784 T10339 T10334 auxpass was,co-introduced
R2785 T10340 T10334 prep with,co-introduced
R2786 T10341 T10340 pobj mut1259,with
R2787 T10342 T10341 punct ", ",mut1259
R2788 T10343 T10341 conj mut198,mut1259
R2789 T10344 T10343 punct ", ",mut198
R2790 T10345 T10343 conj mut72,mut198
R2791 T10346 T10345 cc and,mut72
R2792 T10347 T10348 compound mut,all
R2793 T10348 T10345 conj all,mut72
R2794 T10349 T10334 punct ", ",co-introduced
R2795 T10350 T10334 advmod respectively,co-introduced
R2796 T10351 T10352 punct (,3F
R2797 T10352 T10334 parataxis 3F,co-introduced
R2798 T10353 T10352 compound Fig.,3F
R2799 T10354 T10352 punct ),3F
R2800 T10355 T10334 punct .,co-introduced
R2801 T10357 T10358 det The,activity
R2802 T10358 T10360 nsubjpass activity,reduced
R2803 T10359 T10358 compound transactivaton,activity
R2804 T10361 T10358 prep by,activity
R2805 T10362 T10361 pobj Crx,by
R2806 T10363 T10360 auxpass was,reduced
R2807 T10364 T10360 advmod clearly,reduced
R2808 T10365 T10366 advmod when,co-introduced
R2809 T10366 T10360 advcl co-introduced,reduced
R2810 T10367 T10366 nsubjpass mut198,co-introduced
R2811 T10368 T10367 cc or,mut198
R2812 T10369 T10367 conj mut72,mut198
R2813 T10370 T10366 auxpass was,co-introduced
R2814 T10371 T10360 punct .,reduced
R2815 T10373 T10374 prep On,altered
R2816 T10375 T10376 det the,hand
R2817 T10376 T10373 pobj hand,On
R2818 T10377 T10376 amod other,hand
R2819 T10378 T10374 punct ", ",altered
R2820 T10379 T10380 advmod when,co-transfected
R2821 T10380 T10374 advcl co-transfected,altered
R2822 T10381 T10380 nsubjpass mut1259,co-transfected
R2823 T10382 T10380 auxpass was,co-transfected
R2824 T10383 T10374 punct ", ",altered
R2825 T10384 T10385 det the,activity
R2826 T10385 T10374 nsubjpass activity,altered
R2827 T10386 T10385 compound transactivation,activity
R2828 T10387 T10385 prep by,activity
R2829 T10388 T10387 pobj Crx,by
R2830 T10389 T10374 auxpass was,altered
R2831 T10390 T10374 neg not,altered
R2832 T10391 T10374 punct .,altered
R2833 T10393 T10394 det These,results
R2834 T10394 T10395 nsubj results,suggest
R2835 T10396 T10397 mark that,are
R2836 T10397 T10395 ccomp are,suggest
R2837 T10398 T10399 det the,sites
R2838 T10399 T10397 nsubj sites,are
R2839 T10400 T10401 compound Crx,binding
R2840 T10401 T10399 compound binding,sites
R2841 T10402 T10403 nummod 72,bp
R2842 T10403 T10405 npadvmod bp,upstream
R2843 T10404 T10403 punct -,bp
R2844 T10405 T10399 advmod upstream,sites
R2845 T10406 T10403 cc and,bp
R2846 T10407 T10408 nummod 198,bp
R2847 T10408 T10403 conj bp,bp
R2848 T10409 T10408 punct -,bp
R2849 T10410 T10405 prep from,upstream
R2850 T10411 T10412 det the,site
R2851 T10412 T10410 pobj site,from
R2852 T10413 T10412 compound transcription,site
R2853 T10414 T10412 compound initiation,site
R2854 T10415 T10397 acomp crucial,are
R2855 T10416 T10415 prep for,crucial
R2856 T10417 T10418 det the,regulation
R2857 T10418 T10416 pobj regulation,for
R2858 T10419 T10418 amod direct,regulation
R2859 T10420 T10418 prep of,regulation
R2860 T10421 T10422 compound mr,s
R2861 T10422 T10424 compound s,transcription
R2862 T10423 T10422 punct -,s
R2863 T10424 T10420 pobj transcription,of
R2864 T10425 T10418 prep by,regulation
R2865 T10426 T10425 pobj Crx,by
R2866 T10427 T10395 punct .,suggest