Id |
Subject |
Object |
Predicate |
Lexical cue |
T2332 |
3-7 |
NN |
denotes |
cell |
T2333 |
8-15 |
NN |
denotes |
biology |
T2334 |
16-17 |
-LRB- |
denotes |
[ |
T2335 |
17-18 |
CD |
denotes |
4 |
T2336 |
18-19 |
SYM |
denotes |
- |
T2337 |
19-20 |
CD |
denotes |
6 |
T2338 |
20-21 |
-RRB- |
denotes |
] |
T2339 |
21-22 |
. |
denotes |
. |
T2340 |
22-212 |
sentence |
denotes |
To identify molecules essential in ES cells for these properties, several groups have utilized transcriptome analyses to identify genes specifically expressed in ES cells and early embryos. |
T2341 |
23-25 |
TO |
denotes |
To |
T2342 |
26-34 |
VB |
denotes |
identify |
T2343 |
109-117 |
VBN |
denotes |
utilized |
T2344 |
35-44 |
NNS |
denotes |
molecules |
T2345 |
45-54 |
JJ |
denotes |
essential |
T2346 |
55-57 |
IN |
denotes |
in |
T2347 |
58-60 |
NN |
denotes |
ES |
T2348 |
61-66 |
NNS |
denotes |
cells |
T2349 |
67-70 |
IN |
denotes |
for |
T2350 |
71-76 |
DT |
denotes |
these |
T2351 |
77-87 |
NNS |
denotes |
properties |
T2352 |
87-89 |
, |
denotes |
, |
T2353 |
89-96 |
JJ |
denotes |
several |
T2354 |
97-103 |
NNS |
denotes |
groups |
T2355 |
104-108 |
VBP |
denotes |
have |
T2356 |
118-131 |
NN |
denotes |
transcriptome |
T2357 |
132-140 |
NNS |
denotes |
analyses |
T2358 |
141-143 |
TO |
denotes |
to |
T2359 |
144-152 |
VB |
denotes |
identify |
T2360 |
153-158 |
NNS |
denotes |
genes |
T2361 |
159-171 |
RB |
denotes |
specifically |
T2362 |
172-181 |
VBN |
denotes |
expressed |
T2363 |
182-184 |
IN |
denotes |
in |
T2364 |
185-187 |
NN |
denotes |
ES |
T2365 |
188-193 |
NNS |
denotes |
cells |
T2366 |
194-197 |
CC |
denotes |
and |
T2367 |
198-203 |
JJ |
denotes |
early |
T2368 |
204-211 |
NNS |
denotes |
embryos |
T2369 |
211-212 |
. |
denotes |
. |
T2370 |
212-405 |
sentence |
denotes |
These analyses, including DNA microarray analyses [7] and expressed sequence tag analyses [8-12], identified several common transcripts, including ESG1 that was also designated dppa5 or ECAT2. |
T2371 |
213-218 |
DT |
denotes |
These |
T2372 |
219-227 |
NNS |
denotes |
analyses |
T2373 |
311-321 |
VBD |
denotes |
identified |
T2374 |
227-229 |
, |
denotes |
, |
T2375 |
229-238 |
VBG |
denotes |
including |
T2376 |
239-242 |
NN |
denotes |
DNA |
T2377 |
254-262 |
NNS |
denotes |
analyses |
T2378 |
243-253 |
NN |
denotes |
microarray |
T2379 |
263-264 |
-LRB- |
denotes |
[ |
T2380 |
264-265 |
CD |
denotes |
7 |
T2381 |
265-266 |
-RRB- |
denotes |
] |
T2382 |
267-270 |
CC |
denotes |
and |
T2383 |
271-280 |
VBN |
denotes |
expressed |
T2384 |
281-289 |
NN |
denotes |
sequence |
T2385 |
294-302 |
NNS |
denotes |
analyses |
T2386 |
290-293 |
NN |
denotes |
tag |
T2387 |
303-304 |
-LRB- |
denotes |
[ |
T2388 |
304-305 |
CD |
denotes |
8 |
T2389 |
305-306 |
SYM |
denotes |
- |
T2390 |
306-308 |
CD |
denotes |
12 |
T2391 |
308-309 |
-RRB- |
denotes |
] |
T2392 |
309-311 |
, |
denotes |
, |
T2393 |
322-329 |
JJ |
denotes |
several |
T2394 |
337-348 |
NNS |
denotes |
transcripts |
T2395 |
330-336 |
JJ |
denotes |
common |
T2396 |
348-350 |
, |
denotes |
, |
T2397 |
350-359 |
VBG |
denotes |
including |
T2398 |
360-364 |
NN |
denotes |
ESG1 |
T2399 |
365-369 |
WDT |
denotes |
that |
T2400 |
379-389 |
VBN |
denotes |
designated |
T2401 |
370-373 |
VBD |
denotes |
was |
T2402 |
374-378 |
RB |
denotes |
also |
T2403 |
390-395 |
NN |
denotes |
dppa5 |
T2404 |
396-398 |
CC |
denotes |
or |
T2405 |
399-404 |
NN |
denotes |
ECAT2 |
T2406 |
404-405 |
. |
denotes |
. |
T2407 |
405-533 |
sentence |
denotes |
ESG1 was originally identified as a transcript Ph34 that was down-regulated by retinoic acid in embryonic carcinoma cells [13]. |
T2408 |
406-410 |
NN |
denotes |
ESG1 |
T2409 |
426-436 |
VBN |
denotes |
identified |
T2410 |
411-414 |
VBD |
denotes |
was |
T2411 |
415-425 |
RB |
denotes |
originally |
T2412 |
437-439 |
IN |
denotes |
as |
T2413 |
440-441 |
DT |
denotes |
a |
T2414 |
453-457 |
NN |
denotes |
Ph34 |
T2415 |
442-452 |
NN |
denotes |
transcript |
T2416 |
458-462 |
WDT |
denotes |
that |
T2417 |
472-481 |
VBN |
denotes |
regulated |
T2418 |
463-466 |
VBD |
denotes |
was |
T2419 |
467-471 |
RB |
denotes |
down |
T2420 |
471-472 |
HYPH |
denotes |
- |
T2421 |
482-484 |
IN |
denotes |
by |
T2422 |
485-493 |
JJ |
denotes |
retinoic |
T2423 |
494-498 |
NN |
denotes |
acid |
T2424 |
499-501 |
IN |
denotes |
in |
T2425 |
502-511 |
JJ |
denotes |
embryonic |
T2426 |
512-521 |
NN |
denotes |
carcinoma |
T2427 |
522-527 |
NNS |
denotes |
cells |
T2428 |
528-529 |
-LRB- |
denotes |
[ |
T2429 |
529-531 |
CD |
denotes |
13 |
T2430 |
531-532 |
-RRB- |
denotes |
] |
T2431 |
532-533 |
. |
denotes |
. |
T2432 |
533-620 |
sentence |
denotes |
The expression of this gene was confined in mice to early embryos and germ cells [14]. |
T2433 |
534-537 |
DT |
denotes |
The |
T2434 |
538-548 |
NN |
denotes |
expression |
T2435 |
566-574 |
VBN |
denotes |
confined |
T2436 |
549-551 |
IN |
denotes |
of |
T2437 |
552-556 |
DT |
denotes |
this |
T2438 |
557-561 |
NN |
denotes |
gene |
T2439 |
562-565 |
VBD |
denotes |
was |
T2440 |
575-577 |
IN |
denotes |
in |
T2441 |
578-582 |
NNS |
denotes |
mice |
T2442 |
583-585 |
IN |
denotes |
to |
T2443 |
586-591 |
JJ |
denotes |
early |
T2444 |
592-599 |
NNS |
denotes |
embryos |
T2445 |
600-603 |
CC |
denotes |
and |
T2446 |
604-608 |
NN |
denotes |
germ |
T2447 |
609-614 |
NNS |
denotes |
cells |
T2448 |
615-616 |
-LRB- |
denotes |
[ |
T2449 |
616-618 |
CD |
denotes |
14 |
T2450 |
618-619 |
-RRB- |
denotes |
] |
T2451 |
619-620 |
. |
denotes |
. |
T2452 |
620-747 |
sentence |
denotes |
It is also expressed in pluripotent cells, including ES cells, embryonic germ cells, and multipotent germline stem cells [15]. |
T2453 |
621-623 |
PRP |
denotes |
It |
T2454 |
632-641 |
VBN |
denotes |
expressed |
T2455 |
624-626 |
VBZ |
denotes |
is |
T2456 |
627-631 |
RB |
denotes |
also |
T2457 |
642-644 |
IN |
denotes |
in |
T2458 |
645-656 |
JJ |
denotes |
pluripotent |
T2459 |
657-662 |
NNS |
denotes |
cells |
T2460 |
662-664 |
, |
denotes |
, |
T2461 |
664-673 |
VBG |
denotes |
including |
T2462 |
674-676 |
NN |
denotes |
ES |
T2463 |
677-682 |
NNS |
denotes |
cells |
T2464 |
682-684 |
, |
denotes |
, |
T2465 |
684-693 |
JJ |
denotes |
embryonic |
T2466 |
699-704 |
NNS |
denotes |
cells |
T2467 |
694-698 |
NN |
denotes |
germ |
T2468 |
704-706 |
, |
denotes |
, |
T2469 |
706-709 |
CC |
denotes |
and |
T2470 |
710-721 |
JJ |
denotes |
multipotent |
T2471 |
736-741 |
NNS |
denotes |
cells |
T2472 |
722-730 |
NN |
denotes |
germline |
T2473 |
731-735 |
NN |
denotes |
stem |
T2474 |
742-743 |
-LRB- |
denotes |
[ |
T2475 |
743-745 |
CD |
denotes |
15 |
T2476 |
745-746 |
-RRB- |
denotes |
] |
T2477 |
746-747 |
. |
denotes |
. |
T2478 |
747-864 |
sentence |
denotes |
ESG1 encodes a polypeptide of 118 amino acids that contains a single KH domain, which is an RNA-binding domain [16]. |
T2479 |
748-752 |
NN |
denotes |
ESG1 |
T2480 |
753-760 |
VBZ |
denotes |
encodes |
T2481 |
761-762 |
DT |
denotes |
a |
T2482 |
763-774 |
NN |
denotes |
polypeptide |
T2483 |
775-777 |
IN |
denotes |
of |
T2484 |
778-781 |
CD |
denotes |
118 |
T2485 |
788-793 |
NNS |
denotes |
acids |
T2486 |
782-787 |
NN |
denotes |
amino |
T2487 |
794-798 |
WDT |
denotes |
that |
T2488 |
799-807 |
VBZ |
denotes |
contains |
T2489 |
808-809 |
DT |
denotes |
a |
T2490 |
820-826 |
NN |
denotes |
domain |
T2491 |
810-816 |
JJ |
denotes |
single |
T2492 |
817-819 |
NN |
denotes |
KH |
T2493 |
826-828 |
, |
denotes |
, |
T2494 |
828-833 |
WDT |
denotes |
which |
T2495 |
834-836 |
VBZ |
denotes |
is |
T2496 |
837-839 |
DT |
denotes |
an |
T2497 |
852-858 |
NN |
denotes |
domain |
T2498 |
840-843 |
NN |
denotes |
RNA |
T2499 |
844-851 |
VBG |
denotes |
binding |
T2500 |
843-844 |
HYPH |
denotes |
- |
T2501 |
859-860 |
-LRB- |
denotes |
[ |
T2502 |
860-862 |
CD |
denotes |
16 |
T2503 |
862-863 |
-RRB- |
denotes |
] |
T2504 |
863-864 |
. |
denotes |
. |
T2506 |
865-867 |
PRP |
denotes |
It |
T2507 |
868-875 |
VBZ |
denotes |
remains |
T2508 |
876-883 |
JJ |
denotes |
unclear |
T2509 |
883-885 |
, |
denotes |
, |
T2510 |
885-892 |
RB |
denotes |
however |
T2511 |
892-894 |
, |
denotes |
, |
T2512 |
894-896 |
IN |
denotes |
if |
T2513 |
902-911 |
VBZ |
denotes |
functions |
T2514 |
897-901 |
NN |
denotes |
ESG1 |
T2515 |
912-914 |
IN |
denotes |
as |
T2516 |
915-917 |
DT |
denotes |
an |
T2517 |
930-937 |
NN |
denotes |
protein |
T2518 |
918-921 |
NN |
denotes |
RNA |
T2519 |
922-929 |
VBG |
denotes |
binding |
T2520 |
921-922 |
HYPH |
denotes |
- |
R440 |
T2332 |
T2333 |
compound |
cell,biology |
R442 |
T2334 |
T2335 |
punct |
[,4 |
R444 |
T2336 |
T2337 |
punct |
-,6 |
R445 |
T2337 |
T2335 |
prep |
6,4 |
R446 |
T2338 |
T2335 |
punct |
],4 |
R448 |
T2341 |
T2342 |
aux |
To,identify |
R449 |
T2342 |
T2343 |
advcl |
identify,utilized |
R450 |
T2344 |
T2342 |
dobj |
molecules,identify |
R451 |
T2345 |
T2344 |
relcl |
essential,molecules |
R452 |
T2346 |
T2345 |
prep |
in,essential |
R453 |
T2347 |
T2348 |
compound |
ES,cells |
R454 |
T2348 |
T2346 |
pobj |
cells,in |
R455 |
T2349 |
T2345 |
prep |
for,essential |
R456 |
T2350 |
T2351 |
det |
these,properties |
R457 |
T2351 |
T2349 |
pobj |
properties,for |
R458 |
T2352 |
T2343 |
punct |
", ",utilized |
R459 |
T2353 |
T2354 |
amod |
several,groups |
R460 |
T2354 |
T2343 |
nsubj |
groups,utilized |
R461 |
T2355 |
T2343 |
aux |
have,utilized |
R462 |
T2356 |
T2357 |
compound |
transcriptome,analyses |
R463 |
T2357 |
T2343 |
dobj |
analyses,utilized |
R464 |
T2358 |
T2359 |
aux |
to,identify |
R465 |
T2359 |
T2343 |
advcl |
identify,utilized |
R466 |
T2360 |
T2359 |
dobj |
genes,identify |
R467 |
T2361 |
T2362 |
advmod |
specifically,expressed |
R468 |
T2362 |
T2360 |
acl |
expressed,genes |
R469 |
T2363 |
T2362 |
prep |
in,expressed |
R470 |
T2364 |
T2365 |
compound |
ES,cells |
R471 |
T2365 |
T2363 |
pobj |
cells,in |
R472 |
T2366 |
T2365 |
cc |
and,cells |
R473 |
T2367 |
T2368 |
amod |
early,embryos |
R474 |
T2368 |
T2365 |
conj |
embryos,cells |
R475 |
T2369 |
T2343 |
punct |
.,utilized |
R476 |
T2371 |
T2372 |
det |
These,analyses |
R477 |
T2372 |
T2373 |
nsubj |
analyses,identified |
R478 |
T2374 |
T2372 |
punct |
", ",analyses |
R479 |
T2375 |
T2372 |
prep |
including,analyses |
R480 |
T2376 |
T2377 |
compound |
DNA,analyses |
R481 |
T2377 |
T2375 |
pobj |
analyses,including |
R482 |
T2378 |
T2377 |
compound |
microarray,analyses |
R483 |
T2379 |
T2380 |
punct |
[,7 |
R484 |
T2380 |
T2377 |
parataxis |
7,analyses |
R485 |
T2381 |
T2380 |
punct |
],7 |
R486 |
T2382 |
T2377 |
cc |
and,analyses |
R487 |
T2383 |
T2384 |
amod |
expressed,sequence |
R488 |
T2384 |
T2385 |
compound |
sequence,analyses |
R489 |
T2385 |
T2377 |
conj |
analyses,analyses |
R490 |
T2386 |
T2385 |
compound |
tag,analyses |
R491 |
T2387 |
T2388 |
punct |
[,8 |
R492 |
T2388 |
T2385 |
parataxis |
8,analyses |
R493 |
T2389 |
T2390 |
punct |
-,12 |
R494 |
T2390 |
T2388 |
prep |
12,8 |
R495 |
T2391 |
T2388 |
punct |
],8 |
R496 |
T2392 |
T2373 |
punct |
", ",identified |
R497 |
T2393 |
T2394 |
amod |
several,transcripts |
R498 |
T2394 |
T2373 |
dobj |
transcripts,identified |
R499 |
T2395 |
T2394 |
amod |
common,transcripts |
R500 |
T2396 |
T2394 |
punct |
", ",transcripts |
R501 |
T2397 |
T2394 |
prep |
including,transcripts |
R502 |
T2398 |
T2397 |
pobj |
ESG1,including |
R503 |
T2399 |
T2400 |
dep |
that,designated |
R504 |
T2400 |
T2394 |
relcl |
designated,transcripts |
R505 |
T2401 |
T2400 |
auxpass |
was,designated |
R506 |
T2402 |
T2400 |
advmod |
also,designated |
R507 |
T2403 |
T2400 |
oprd |
dppa5,designated |
R508 |
T2404 |
T2403 |
cc |
or,dppa5 |
R509 |
T2405 |
T2403 |
conj |
ECAT2,dppa5 |
R510 |
T2406 |
T2373 |
punct |
.,identified |
R511 |
T2408 |
T2409 |
nsubjpass |
ESG1,identified |
R512 |
T2410 |
T2409 |
auxpass |
was,identified |
R513 |
T2411 |
T2409 |
advmod |
originally,identified |
R514 |
T2412 |
T2409 |
prep |
as,identified |
R515 |
T2413 |
T2414 |
det |
a,Ph34 |
R516 |
T2414 |
T2412 |
pobj |
Ph34,as |
R517 |
T2415 |
T2414 |
compound |
transcript,Ph34 |
R518 |
T2416 |
T2417 |
dep |
that,regulated |
R519 |
T2417 |
T2414 |
relcl |
regulated,Ph34 |
R520 |
T2418 |
T2417 |
auxpass |
was,regulated |
R521 |
T2419 |
T2417 |
advmod |
down,regulated |
R522 |
T2420 |
T2417 |
punct |
-,regulated |
R523 |
T2421 |
T2417 |
agent |
by,regulated |
R524 |
T2422 |
T2423 |
amod |
retinoic,acid |
R525 |
T2423 |
T2421 |
pobj |
acid,by |
R526 |
T2424 |
T2417 |
prep |
in,regulated |
R527 |
T2425 |
T2426 |
amod |
embryonic,carcinoma |
R528 |
T2426 |
T2427 |
compound |
carcinoma,cells |
R529 |
T2427 |
T2424 |
pobj |
cells,in |
R530 |
T2428 |
T2429 |
punct |
[,13 |
R531 |
T2429 |
T2417 |
parataxis |
13,regulated |
R532 |
T2430 |
T2429 |
punct |
],13 |
R533 |
T2431 |
T2409 |
punct |
.,identified |
R534 |
T2433 |
T2434 |
det |
The,expression |
R535 |
T2434 |
T2435 |
nsubjpass |
expression,confined |
R536 |
T2436 |
T2434 |
prep |
of,expression |
R537 |
T2437 |
T2438 |
det |
this,gene |
R538 |
T2438 |
T2436 |
pobj |
gene,of |
R539 |
T2439 |
T2435 |
auxpass |
was,confined |
R540 |
T2440 |
T2435 |
prep |
in,confined |
R541 |
T2441 |
T2440 |
pobj |
mice,in |
R542 |
T2442 |
T2435 |
prep |
to,confined |
R543 |
T2443 |
T2444 |
amod |
early,embryos |
R544 |
T2444 |
T2442 |
pobj |
embryos,to |
R545 |
T2445 |
T2444 |
cc |
and,embryos |
R546 |
T2446 |
T2447 |
compound |
germ,cells |
R547 |
T2447 |
T2444 |
conj |
cells,embryos |
R548 |
T2448 |
T2449 |
punct |
[,14 |
R549 |
T2449 |
T2435 |
parataxis |
14,confined |
R550 |
T2450 |
T2449 |
punct |
],14 |
R551 |
T2451 |
T2435 |
punct |
.,confined |
R552 |
T2453 |
T2454 |
nsubjpass |
It,expressed |
R553 |
T2455 |
T2454 |
auxpass |
is,expressed |
R554 |
T2456 |
T2454 |
advmod |
also,expressed |
R555 |
T2457 |
T2454 |
prep |
in,expressed |
R556 |
T2458 |
T2459 |
amod |
pluripotent,cells |
R557 |
T2459 |
T2457 |
pobj |
cells,in |
R558 |
T2460 |
T2459 |
punct |
", ",cells |
R559 |
T2461 |
T2459 |
prep |
including,cells |
R560 |
T2462 |
T2463 |
compound |
ES,cells |
R561 |
T2463 |
T2461 |
pobj |
cells,including |
R562 |
T2464 |
T2463 |
punct |
", ",cells |
R563 |
T2465 |
T2466 |
amod |
embryonic,cells |
R564 |
T2466 |
T2463 |
conj |
cells,cells |
R565 |
T2467 |
T2466 |
compound |
germ,cells |
R566 |
T2468 |
T2466 |
punct |
", ",cells |
R567 |
T2469 |
T2466 |
cc |
and,cells |
R568 |
T2470 |
T2471 |
amod |
multipotent,cells |
R569 |
T2471 |
T2466 |
conj |
cells,cells |
R570 |
T2472 |
T2471 |
compound |
germline,cells |
R571 |
T2473 |
T2471 |
compound |
stem,cells |
R572 |
T2474 |
T2475 |
punct |
[,15 |
R573 |
T2475 |
T2454 |
parataxis |
15,expressed |
R574 |
T2476 |
T2475 |
punct |
],15 |
R575 |
T2477 |
T2454 |
punct |
.,expressed |
R576 |
T2479 |
T2480 |
nsubj |
ESG1,encodes |
R577 |
T2481 |
T2482 |
det |
a,polypeptide |
R578 |
T2482 |
T2480 |
dobj |
polypeptide,encodes |
R579 |
T2483 |
T2482 |
prep |
of,polypeptide |
R580 |
T2484 |
T2485 |
nummod |
118,acids |
R581 |
T2485 |
T2483 |
pobj |
acids,of |
R582 |
T2486 |
T2485 |
compound |
amino,acids |
R583 |
T2487 |
T2488 |
dep |
that,contains |
R584 |
T2488 |
T2482 |
relcl |
contains,polypeptide |
R585 |
T2489 |
T2490 |
det |
a,domain |
R586 |
T2490 |
T2488 |
dobj |
domain,contains |
R587 |
T2491 |
T2490 |
amod |
single,domain |
R588 |
T2492 |
T2490 |
compound |
KH,domain |
R589 |
T2493 |
T2490 |
punct |
", ",domain |
R590 |
T2494 |
T2495 |
dep |
which,is |
R591 |
T2495 |
T2490 |
relcl |
is,domain |
R592 |
T2496 |
T2497 |
det |
an,domain |
R593 |
T2497 |
T2495 |
attr |
domain,is |
R594 |
T2498 |
T2499 |
npadvmod |
RNA,binding |
R595 |
T2499 |
T2497 |
amod |
binding,domain |
R596 |
T2500 |
T2499 |
punct |
-,binding |
R597 |
T2501 |
T2502 |
punct |
[,16 |
R598 |
T2502 |
T2495 |
parataxis |
16,is |
R599 |
T2503 |
T2502 |
punct |
],16 |
R600 |
T2504 |
T2480 |
punct |
.,encodes |
R601 |
T2506 |
T2507 |
nsubj |
It,remains |
R602 |
T2508 |
T2507 |
acomp |
unclear,remains |
R603 |
T2509 |
T2507 |
punct |
", ",remains |
R604 |
T2510 |
T2507 |
advmod |
however,remains |
R605 |
T2511 |
T2507 |
punct |
", ",remains |
R606 |
T2512 |
T2513 |
mark |
if,functions |
R607 |
T2513 |
T2507 |
ccomp |
functions,remains |
R608 |
T2514 |
T2513 |
nsubj |
ESG1,functions |
R609 |
T2515 |
T2513 |
prep |
as,functions |
R610 |
T2516 |
T2517 |
det |
an,protein |
R611 |
T2517 |
T2515 |
pobj |
protein,as |
R612 |
T2518 |
T2519 |
npadvmod |
RNA,binding |
R613 |
T2519 |
T2517 |
amod |
binding,protein |
R614 |
T2520 |
T2519 |
punct |
-,binding |