Id |
Subject |
Object |
Predicate |
Lexical cue |
T10420 |
0-3 |
DT |
denotes |
The |
T10421 |
11-19 |
NN |
denotes |
sequence |
T10422 |
4-10 |
VBG |
denotes |
coding |
T10423 |
32-41 |
VBN |
denotes |
amplified |
T10424 |
20-22 |
IN |
denotes |
of |
T10425 |
23-27 |
NN |
denotes |
Esg1 |
T10426 |
28-31 |
VBD |
denotes |
was |
T10427 |
42-44 |
IN |
denotes |
by |
T10428 |
45-48 |
NN |
denotes |
PCR |
T10429 |
49-53 |
IN |
denotes |
with |
T10430 |
54-57 |
DT |
denotes |
the |
T10431 |
168-175 |
NNS |
denotes |
primers |
T10432 |
58-62 |
NN |
denotes |
pH34 |
T10433 |
66-67 |
NN |
denotes |
s |
T10434 |
62-63 |
HYPH |
denotes |
- |
T10435 |
63-65 |
NN |
denotes |
gw |
T10436 |
65-66 |
HYPH |
denotes |
- |
T10437 |
68-69 |
-LRB- |
denotes |
( |
T10438 |
73-106 |
NN |
denotes |
AAAAAGCAGGCTGGATGATGGTGACCCTCGTGA |
T10439 |
69-70 |
CD |
denotes |
5 |
T10440 |
70-71 |
SYM |
denotes |
' |
T10441 |
71-72 |
HYPH |
denotes |
- |
T10442 |
106-107 |
HYPH |
denotes |
- |
T10443 |
107-108 |
CD |
denotes |
3 |
T10444 |
108-109 |
SYM |
denotes |
' |
T10445 |
109-110 |
-RRB- |
denotes |
) |
T10446 |
111-114 |
CC |
denotes |
and |
T10447 |
115-119 |
NN |
denotes |
pH34 |
T10448 |
123-125 |
NN |
denotes |
as |
T10449 |
119-120 |
HYPH |
denotes |
- |
T10450 |
120-122 |
NN |
denotes |
gw |
T10451 |
122-123 |
HYPH |
denotes |
- |
T10452 |
126-127 |
-LRB- |
denotes |
( |
T10453 |
131-163 |
NN |
denotes |
AGAAAGCTGGGTCTGCATCCAGGTCGGAGACA |
T10454 |
127-128 |
CD |
denotes |
5 |
T10455 |
128-129 |
SYM |
denotes |
' |
T10456 |
129-130 |
HYPH |
denotes |
- |
T10457 |
163-164 |
HYPH |
denotes |
- |
T10458 |
164-165 |
CD |
denotes |
3 |
T10459 |
165-166 |
SYM |
denotes |
' |
T10460 |
166-167 |
-RRB- |
denotes |
) |
T10461 |
175-176 |
. |
denotes |
. |
T10462 |
176-269 |
sentence |
denotes |
To construct pDONR-pH34, the resulting PCR product was subcloned into pDONR201 (Invitrogen). |
T10463 |
177-179 |
TO |
denotes |
To |
T10464 |
180-189 |
VB |
denotes |
construct |
T10465 |
232-241 |
VBN |
denotes |
subcloned |
T10466 |
190-195 |
NN |
denotes |
pDONR |
T10467 |
196-200 |
NN |
denotes |
pH34 |
T10468 |
195-196 |
HYPH |
denotes |
- |
T10469 |
200-202 |
, |
denotes |
, |
T10470 |
202-205 |
DT |
denotes |
the |
T10471 |
220-227 |
NN |
denotes |
product |
T10472 |
206-215 |
VBG |
denotes |
resulting |
T10473 |
216-219 |
NN |
denotes |
PCR |
T10474 |
228-231 |
VBD |
denotes |
was |
T10475 |
242-246 |
IN |
denotes |
into |
T10476 |
247-255 |
NN |
denotes |
pDONR201 |
T10477 |
256-257 |
-LRB- |
denotes |
( |
T10478 |
257-267 |
NNP |
denotes |
Invitrogen |
T10479 |
267-268 |
-RRB- |
denotes |
) |
T10480 |
268-269 |
. |
denotes |
. |
T10481 |
269-342 |
sentence |
denotes |
pDONR-pH34 was interacted with pDEST17 (Invitrogen) by LR recombination. |
T10482 |
270-275 |
NN |
denotes |
pDONR |
T10483 |
276-280 |
NN |
denotes |
pH34 |
T10484 |
275-276 |
HYPH |
denotes |
- |
T10485 |
285-295 |
VBN |
denotes |
interacted |
T10486 |
281-284 |
VBD |
denotes |
was |
T10487 |
296-300 |
IN |
denotes |
with |
T10488 |
301-308 |
NN |
denotes |
pDEST17 |
T10489 |
309-310 |
-LRB- |
denotes |
( |
T10490 |
310-320 |
NNP |
denotes |
Invitrogen |
T10491 |
320-321 |
-RRB- |
denotes |
) |
T10492 |
322-324 |
IN |
denotes |
by |
T10493 |
325-327 |
NN |
denotes |
LR |
T10494 |
328-341 |
NN |
denotes |
recombination |
T10495 |
341-342 |
. |
denotes |
. |
T10496 |
342-528 |
sentence |
denotes |
After introduction of the resulting expression vector pDEST17-pH34 into BL21-AI E. coli (Invitrogen), recombinant protein production was induced according to the manufacture's protocol. |
T10497 |
343-348 |
IN |
denotes |
After |
T10498 |
480-487 |
VBN |
denotes |
induced |
T10499 |
349-361 |
NN |
denotes |
introduction |
T10500 |
362-364 |
IN |
denotes |
of |
T10501 |
365-368 |
DT |
denotes |
the |
T10502 |
390-396 |
NN |
denotes |
vector |
T10503 |
369-378 |
VBG |
denotes |
resulting |
T10504 |
379-389 |
NN |
denotes |
expression |
T10505 |
397-404 |
NN |
denotes |
pDEST17 |
T10506 |
405-409 |
NN |
denotes |
pH34 |
T10507 |
404-405 |
HYPH |
denotes |
- |
T10508 |
410-414 |
IN |
denotes |
into |
T10509 |
415-419 |
NN |
denotes |
BL21 |
T10510 |
420-422 |
NN |
denotes |
AI |
T10511 |
419-420 |
HYPH |
denotes |
- |
T10512 |
423-425 |
FW |
denotes |
E. |
T10513 |
426-430 |
FW |
denotes |
coli |
T10514 |
431-432 |
-LRB- |
denotes |
( |
T10515 |
432-442 |
NNP |
denotes |
Invitrogen |
T10516 |
442-443 |
-RRB- |
denotes |
) |
T10517 |
443-445 |
, |
denotes |
, |
T10518 |
445-456 |
JJ |
denotes |
recombinant |
T10519 |
457-464 |
NN |
denotes |
protein |
T10520 |
465-475 |
NN |
denotes |
production |
T10521 |
476-479 |
VBD |
denotes |
was |
T10522 |
488-497 |
VBG |
denotes |
according |
T10523 |
498-500 |
IN |
denotes |
to |
T10524 |
501-504 |
DT |
denotes |
the |
T10525 |
505-516 |
NN |
denotes |
manufacture |
T10526 |
519-527 |
NN |
denotes |
protocol |
T10527 |
516-518 |
POS |
denotes |
's |
T10528 |
527-528 |
. |
denotes |
. |
T10529 |
528-668 |
sentence |
denotes |
Histidine-tagged ESG1 was purified using Ni-nitrilotriacetic acid agarose (Qiagen) under denaturing conditions in the presence of 8 M urea. |
T10530 |
529-538 |
NN |
denotes |
Histidine |
T10531 |
539-545 |
VBN |
denotes |
tagged |
T10532 |
538-539 |
HYPH |
denotes |
- |
T10533 |
546-550 |
NN |
denotes |
ESG1 |
T10534 |
555-563 |
VBN |
denotes |
purified |
T10535 |
551-554 |
VBD |
denotes |
was |
T10536 |
564-569 |
VBG |
denotes |
using |
T10537 |
570-572 |
NN |
denotes |
Ni |
T10538 |
595-602 |
NN |
denotes |
agarose |
T10539 |
572-573 |
: |
denotes |
- |
T10540 |
573-589 |
JJ |
denotes |
nitrilotriacetic |
T10541 |
590-594 |
NN |
denotes |
acid |
T10542 |
603-604 |
-LRB- |
denotes |
( |
T10543 |
604-610 |
NNP |
denotes |
Qiagen |
T10544 |
610-611 |
-RRB- |
denotes |
) |
T10545 |
612-617 |
IN |
denotes |
under |
T10546 |
618-628 |
NN |
denotes |
denaturing |
T10547 |
629-639 |
NNS |
denotes |
conditions |
T10548 |
640-642 |
IN |
denotes |
in |
T10549 |
643-646 |
DT |
denotes |
the |
T10550 |
647-655 |
NN |
denotes |
presence |
T10551 |
656-658 |
IN |
denotes |
of |
T10552 |
659-660 |
CD |
denotes |
8 |
T10553 |
661-662 |
NN |
denotes |
M |
T10554 |
663-667 |
NN |
denotes |
urea |
T10555 |
667-668 |
. |
denotes |
. |
T10556 |
668-816 |
sentence |
denotes |
After dialysis against 6 M urea, the recombinant proteins were injected into New Zealand White rabbits to generate anti-ESG1 polyclonal antibodies. |
T10557 |
669-674 |
IN |
denotes |
After |
T10558 |
732-740 |
VBN |
denotes |
injected |
T10559 |
675-683 |
NN |
denotes |
dialysis |
T10560 |
684-691 |
IN |
denotes |
against |
T10561 |
692-693 |
CD |
denotes |
6 |
T10562 |
694-695 |
NN |
denotes |
M |
T10563 |
696-700 |
NN |
denotes |
urea |
T10564 |
700-702 |
, |
denotes |
, |
T10565 |
702-705 |
DT |
denotes |
the |
T10566 |
718-726 |
NN |
denotes |
proteins |
T10567 |
706-717 |
JJ |
denotes |
recombinant |
T10568 |
727-731 |
VBD |
denotes |
were |
T10569 |
741-745 |
IN |
denotes |
into |
T10570 |
746-749 |
NNP |
denotes |
New |
T10571 |
750-757 |
NNP |
denotes |
Zealand |
T10572 |
764-771 |
NNS |
denotes |
rabbits |
T10573 |
758-763 |
JJ |
denotes |
White |
T10574 |
772-774 |
TO |
denotes |
to |
T10575 |
775-783 |
VB |
denotes |
generate |
T10576 |
784-793 |
JJ |
denotes |
anti-ESG1 |
T10577 |
805-815 |
NNS |
denotes |
antibodies |
T10578 |
794-804 |
JJ |
denotes |
polyclonal |
T10579 |
815-816 |
. |
denotes |
. |
R2895 |
T10420 |
T10421 |
det |
The,sequence |
R2896 |
T10421 |
T10423 |
nsubjpass |
sequence,amplified |
R2897 |
T10422 |
T10421 |
amod |
coding,sequence |
R2898 |
T10424 |
T10421 |
prep |
of,sequence |
R2899 |
T10425 |
T10424 |
pobj |
Esg1,of |
R2900 |
T10426 |
T10423 |
auxpass |
was,amplified |
R2901 |
T10427 |
T10423 |
agent |
by,amplified |
R2902 |
T10428 |
T10427 |
pobj |
PCR,by |
R2903 |
T10429 |
T10423 |
prep |
with,amplified |
R2904 |
T10430 |
T10431 |
det |
the,primers |
R2905 |
T10431 |
T10429 |
pobj |
primers,with |
R2906 |
T10432 |
T10433 |
nmod |
pH34,s |
R2907 |
T10433 |
T10431 |
nmod |
s,primers |
R2908 |
T10434 |
T10433 |
punct |
-,s |
R2909 |
T10435 |
T10433 |
nmod |
gw,s |
R2910 |
T10436 |
T10433 |
punct |
-,s |
R2911 |
T10437 |
T10438 |
punct |
(,AAAAAGCAGGCTGGATGATGGTGACCCTCGTGA |
R2912 |
T10438 |
T10433 |
parataxis |
AAAAAGCAGGCTGGATGATGGTGACCCTCGTGA,s |
R2913 |
T10439 |
T10438 |
nummod |
5,AAAAAGCAGGCTGGATGATGGTGACCCTCGTGA |
R2914 |
T10440 |
T10439 |
punct |
',5 |
R2915 |
T10441 |
T10438 |
punct |
-,AAAAAGCAGGCTGGATGATGGTGACCCTCGTGA |
R2916 |
T10442 |
T10438 |
punct |
-,AAAAAGCAGGCTGGATGATGGTGACCCTCGTGA |
R2917 |
T10443 |
T10438 |
nummod |
3,AAAAAGCAGGCTGGATGATGGTGACCCTCGTGA |
R2918 |
T10444 |
T10438 |
punct |
',AAAAAGCAGGCTGGATGATGGTGACCCTCGTGA |
R2919 |
T10445 |
T10438 |
punct |
),AAAAAGCAGGCTGGATGATGGTGACCCTCGTGA |
R2920 |
T10446 |
T10433 |
cc |
and,s |
R2921 |
T10447 |
T10448 |
compound |
pH34,as |
R2922 |
T10448 |
T10433 |
conj |
as,s |
R2923 |
T10449 |
T10448 |
punct |
-,as |
R2924 |
T10450 |
T10448 |
compound |
gw,as |
R2925 |
T10451 |
T10448 |
punct |
-,as |
R2926 |
T10452 |
T10453 |
punct |
(,AGAAAGCTGGGTCTGCATCCAGGTCGGAGACA |
R2927 |
T10453 |
T10448 |
parataxis |
AGAAAGCTGGGTCTGCATCCAGGTCGGAGACA,as |
R2928 |
T10454 |
T10453 |
nummod |
5,AGAAAGCTGGGTCTGCATCCAGGTCGGAGACA |
R2929 |
T10455 |
T10454 |
punct |
',5 |
R2930 |
T10456 |
T10453 |
punct |
-,AGAAAGCTGGGTCTGCATCCAGGTCGGAGACA |
R2931 |
T10457 |
T10453 |
punct |
-,AGAAAGCTGGGTCTGCATCCAGGTCGGAGACA |
R2932 |
T10458 |
T10453 |
nummod |
3,AGAAAGCTGGGTCTGCATCCAGGTCGGAGACA |
R2933 |
T10459 |
T10453 |
punct |
',AGAAAGCTGGGTCTGCATCCAGGTCGGAGACA |
R2934 |
T10460 |
T10453 |
punct |
),AGAAAGCTGGGTCTGCATCCAGGTCGGAGACA |
R2935 |
T10461 |
T10423 |
punct |
.,amplified |
R2936 |
T10463 |
T10464 |
aux |
To,construct |
R2937 |
T10464 |
T10465 |
advcl |
construct,subcloned |
R2938 |
T10466 |
T10467 |
compound |
pDONR,pH34 |
R2939 |
T10467 |
T10464 |
dobj |
pH34,construct |
R2940 |
T10468 |
T10467 |
punct |
-,pH34 |
R2941 |
T10469 |
T10465 |
punct |
", ",subcloned |
R2942 |
T10470 |
T10471 |
det |
the,product |
R2943 |
T10471 |
T10465 |
nsubjpass |
product,subcloned |
R2944 |
T10472 |
T10471 |
amod |
resulting,product |
R2945 |
T10473 |
T10471 |
compound |
PCR,product |
R2946 |
T10474 |
T10465 |
auxpass |
was,subcloned |
R2947 |
T10475 |
T10465 |
prep |
into,subcloned |
R2948 |
T10476 |
T10475 |
pobj |
pDONR201,into |
R2949 |
T10477 |
T10478 |
punct |
(,Invitrogen |
R2950 |
T10478 |
T10476 |
parataxis |
Invitrogen,pDONR201 |
R2951 |
T10479 |
T10478 |
punct |
),Invitrogen |
R2952 |
T10480 |
T10465 |
punct |
.,subcloned |
R2953 |
T10482 |
T10483 |
compound |
pDONR,pH34 |
R2954 |
T10483 |
T10485 |
nsubjpass |
pH34,interacted |
R2955 |
T10484 |
T10483 |
punct |
-,pH34 |
R2956 |
T10486 |
T10485 |
auxpass |
was,interacted |
R2957 |
T10487 |
T10485 |
prep |
with,interacted |
R2958 |
T10488 |
T10487 |
pobj |
pDEST17,with |
R2959 |
T10489 |
T10490 |
punct |
(,Invitrogen |
R2960 |
T10490 |
T10488 |
parataxis |
Invitrogen,pDEST17 |
R2961 |
T10491 |
T10490 |
punct |
),Invitrogen |
R2962 |
T10492 |
T10485 |
prep |
by,interacted |
R2963 |
T10493 |
T10494 |
compound |
LR,recombination |
R2964 |
T10494 |
T10492 |
pobj |
recombination,by |
R2965 |
T10495 |
T10485 |
punct |
.,interacted |
R2966 |
T10497 |
T10498 |
prep |
After,induced |
R2967 |
T10499 |
T10497 |
pobj |
introduction,After |
R2968 |
T10500 |
T10499 |
prep |
of,introduction |
R2969 |
T10501 |
T10502 |
det |
the,vector |
R2970 |
T10502 |
T10500 |
pobj |
vector,of |
R2971 |
T10503 |
T10502 |
amod |
resulting,vector |
R2972 |
T10504 |
T10502 |
compound |
expression,vector |
R2973 |
T10505 |
T10506 |
compound |
pDEST17,pH34 |
R2974 |
T10506 |
T10502 |
appos |
pH34,vector |
R2975 |
T10507 |
T10506 |
punct |
-,pH34 |
R2976 |
T10508 |
T10499 |
prep |
into,introduction |
R2977 |
T10509 |
T10510 |
compound |
BL21,AI |
R2978 |
T10510 |
T10508 |
pobj |
AI,into |
R2979 |
T10511 |
T10510 |
punct |
-,AI |
R2980 |
T10512 |
T10510 |
nmod |
E.,AI |
R2981 |
T10513 |
T10510 |
nmod |
coli,AI |
R2982 |
T10514 |
T10515 |
punct |
(,Invitrogen |
R2983 |
T10515 |
T10499 |
parataxis |
Invitrogen,introduction |
R2984 |
T10516 |
T10515 |
punct |
),Invitrogen |
R2985 |
T10517 |
T10498 |
punct |
", ",induced |
R2986 |
T10518 |
T10519 |
amod |
recombinant,protein |
R2987 |
T10519 |
T10520 |
compound |
protein,production |
R2988 |
T10520 |
T10498 |
nsubjpass |
production,induced |
R2989 |
T10521 |
T10498 |
auxpass |
was,induced |
R2990 |
T10522 |
T10498 |
prep |
according,induced |
R2991 |
T10523 |
T10522 |
prep |
to,according |
R2992 |
T10524 |
T10525 |
det |
the,manufacture |
R2993 |
T10525 |
T10526 |
poss |
manufacture,protocol |
R2994 |
T10526 |
T10523 |
pobj |
protocol,to |
R2995 |
T10527 |
T10525 |
case |
's,manufacture |
R2996 |
T10528 |
T10498 |
punct |
.,induced |
R2997 |
T10530 |
T10531 |
npadvmod |
Histidine,tagged |
R2998 |
T10531 |
T10533 |
amod |
tagged,ESG1 |
R2999 |
T10532 |
T10531 |
punct |
-,tagged |
R3000 |
T10533 |
T10534 |
nsubjpass |
ESG1,purified |
R3001 |
T10535 |
T10534 |
auxpass |
was,purified |
R3002 |
T10536 |
T10534 |
advcl |
using,purified |
R3003 |
T10537 |
T10538 |
nmod |
Ni,agarose |
R3004 |
T10538 |
T10536 |
dobj |
agarose,using |
R3005 |
T10539 |
T10537 |
punct |
-,Ni |
R3006 |
T10540 |
T10537 |
amod |
nitrilotriacetic,Ni |
R3007 |
T10541 |
T10538 |
compound |
acid,agarose |
R3008 |
T10542 |
T10543 |
punct |
(,Qiagen |
R3009 |
T10543 |
T10538 |
parataxis |
Qiagen,agarose |
R3010 |
T10544 |
T10543 |
punct |
),Qiagen |
R3011 |
T10545 |
T10536 |
prep |
under,using |
R3012 |
T10546 |
T10547 |
compound |
denaturing,conditions |
R3013 |
T10547 |
T10545 |
pobj |
conditions,under |
R3014 |
T10548 |
T10536 |
prep |
in,using |
R3015 |
T10549 |
T10550 |
det |
the,presence |
R3016 |
T10550 |
T10548 |
pobj |
presence,in |
R3017 |
T10551 |
T10550 |
prep |
of,presence |
R3018 |
T10552 |
T10553 |
nummod |
8,M |
R3019 |
T10553 |
T10554 |
compound |
M,urea |
R3020 |
T10554 |
T10551 |
pobj |
urea,of |
R3021 |
T10555 |
T10534 |
punct |
.,purified |
R3022 |
T10557 |
T10558 |
prep |
After,injected |
R3023 |
T10559 |
T10557 |
pobj |
dialysis,After |
R3024 |
T10560 |
T10559 |
prep |
against,dialysis |
R3025 |
T10561 |
T10562 |
nummod |
6,M |
R3026 |
T10562 |
T10563 |
compound |
M,urea |
R3027 |
T10563 |
T10560 |
pobj |
urea,against |
R3028 |
T10564 |
T10558 |
punct |
", ",injected |
R3029 |
T10565 |
T10566 |
det |
the,proteins |
R3030 |
T10566 |
T10558 |
nsubjpass |
proteins,injected |
R3031 |
T10567 |
T10566 |
amod |
recombinant,proteins |
R3032 |
T10568 |
T10558 |
auxpass |
were,injected |
R3033 |
T10569 |
T10558 |
prep |
into,injected |
R3034 |
T10570 |
T10571 |
nmod |
New,Zealand |
R3035 |
T10571 |
T10572 |
nmod |
Zealand,rabbits |
R3036 |
T10572 |
T10569 |
pobj |
rabbits,into |
R3037 |
T10573 |
T10572 |
amod |
White,rabbits |
R3038 |
T10574 |
T10575 |
aux |
to,generate |
R3039 |
T10575 |
T10558 |
advcl |
generate,injected |
R3040 |
T10576 |
T10577 |
amod |
anti-ESG1,antibodies |
R3041 |
T10577 |
T10575 |
dobj |
antibodies,generate |
R3042 |
T10578 |
T10577 |
amod |
polyclonal,antibodies |
R3043 |
T10579 |
T10558 |
punct |
.,injected |