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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/13912","sourcedb":"PMC","sourceid":"13912","source_url":"http://www.ncbi.nlm.nih.gov/pmc/13912","text":"Altered expression of estrogen receptor-α variant messenger RNAs \t\t between adjacent normal breast and breast tumor tissues \n\nUsing semiquantitative reverse transcription-polymerase chain \t\t\t reaction assays, we investigated the expression of variant messenger RNAs \t\t\t relative to wild-type estrogen receptor (ER)-α messenger RNA in normal \t\t\t breast tissues and their adjacent matched breast tumor tissues. Higher ER \t\t\t variant truncated after sequences encoding exon 2 of the wild-type ER-α \t\t\t (ERC4) messenger RNA and a lower exon 3 deleted ER-α variant (ERD3) \t\t\t messenger RNA relative expression in the tumor compartment were observed in the \t\t\t ER-positive/PR-positive and the ER-positive subsets, respectively. A \t\t\t significantly higher relative exp","divisions":[{"label":"Title","span":{"begin":0,"end":124}}],"tracks":[]}