PMC:13902 / 8688-9259 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/13902","sourcedb":"PMC","sourceid":"13902","source_url":"http://www.ncbi.nlm.nih.gov/pmc/13902","text":"One major goal in the field of prevention is the identification of surrogate biomarkers that might rapidly predict the effect of a given agent on the primary end-point of cancer incidence. The most informative markers are those with modulation that is likely to be directly related to the preventive effect, and a compelling argument can be made that TGF-βs may fall into this category. However, the present data in a well-established preclinical model of breast cancer, employing a variety of highly effective chemopreventive regimens, suggest that this is not the case.","tracks":[]}