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PMC:138691 / 0-1192 JSONTXT

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craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T18 0-5 PR:000004804 denotes BRCA2
T19 112-118 UBERON:0000310 denotes breast
T20 141-145 SO:0000704 denotes gene
T21 146-151 PR:000004804 denotes BRCA2
T22 155-165 GO:0006281 denotes DNA repair
T23 190-197 SO:0000704 denotes genetic
T24 232-237 PR:000004804 denotes BRCA2
T25 241-259 _FRAGMENT denotes homology-dependent
T26 278-312 GO:0000724 denotes repair of DNA double-strand breaks
T27 261-276 _FRAGMENT denotes recombinational
T28 395-400 PR:000004804 denotes BRCA2
T29 427-449 GO:0000725 denotes recombinational repair
T30 451-456 PR:000004804 denotes BRCA2
T31 526-536 NCBITaxon:2759 denotes eukaryotic
T32 549-554 PR:000013672 denotes RAD51
T33 732-737 PR:000004804 denotes BRCA2
T34 741-746 PR:000013672 denotes RAD51
T35 756-762 GO:0006281 denotes repair
T218 771-776 PR:000004804 denotes BRCA2
T219 792-798 UBERON:0000310 denotes breast
T220 821-825 SO:0000704 denotes gene
T221 928-934 UBERON:0000310 denotes breast
T222 965-970 PR:000004804 denotes BRCA2
T223 1008-1019 SO:0000704 denotes genetically
R1 T26 T25 _lexicallyChainedTo repair of DNA double-strand breaks,homology-dependent
R2 T26 T27 _lexicallyChainedTo repair of DNA double-strand breaks,recombinational

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T189 278-312 GO:0000724 denotes repair of DNA double-strand breaks
T190 261-276 GO_SO_EXT:sequence_rearrangement_process denotes recombinational
T191 261-276 _FRAGMENT denotes recombinational
T192 288-291 CHEBI_SO_EXT:DNA denotes DNA
T193 395-400 PR_EXT:000004804 denotes BRCA2
T194 427-442 GO_SO_EXT:sequence_rearrangement_process denotes recombinational
T195 427-449 GO:0000725 denotes recombinational repair
T196 451-456 PR_EXT:000004804 denotes BRCA2
T197 480-493 GO_SO_EXT:sequence_rearrangement_process denotes recombination
T198 526-536 NCBITaxon:2759 denotes eukaryotic
T199 537-548 GO_EXT:recombinase denotes recombinase
T200 549-554 PR_EXT:000013672 denotes RAD51
T201 732-737 PR_EXT:000004804 denotes BRCA2
T202 741-746 PR_EXT:000013672 denotes RAD51
T203 756-762 GO:0006281 denotes repair
T333 771-776 PR_EXT:000004804 denotes BRCA2
T334 792-798 UBERON:0000310 denotes breast
T335 821-825 SO_EXT:0000704 denotes gene
T336 880-887 SO_EXT:sequence_cloning_process denotes cloning
T337 928-934 UBERON:0000310 denotes breast
T338 947-952 CL_GO_EXT:cell denotes Cells
T339 958-964 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T340 965-970 PR_EXT:000004804 denotes BRCA2
T341 971-978 CHEBI_PR_EXT:protein denotes protein
T342 1001-1006 CL_GO_EXT:cell denotes cells
T343 1008-1019 SO_EXT:0000704 denotes genetically
T344 1050-1061 GO_SO_EXT:chromosome denotes chromosomal
T345 1062-1076 GO_SO_EXT:sequence_rearrangement_entity_or_process denotes rearrangements
T346 1088-1096 SO_EXT:biological_sequence denotes sequence
T347 1111-1118 CHEBI_PR_EXT:protein denotes protein
T348 1125-1136 CHEBI_SO_EXT:amino_acid denotes amino acids
T179 0-5 PR_EXT:000004804 denotes BRCA2
T180 21-34 GO_SO_EXT:sequence_rearrangement_process denotes recombination
T181 112-118 UBERON:0000310 denotes breast
T182 141-145 SO_EXT:0000704 denotes gene
T183 146-151 PR_EXT:000004804 denotes BRCA2
T184 155-158 CHEBI_SO_EXT:DNA denotes DNA
T185 155-165 GO:0006281 denotes DNA repair
T186 190-197 SO_EXT:0000704 denotes genetic
T187 232-237 PR_EXT:000004804 denotes BRCA2
T188 241-259 _FRAGMENT denotes homology-dependent
R133 T189 T188 _lexicallyChainedTo repair of DNA double-strand breaks,homology-dependent
R134 T189 T191 _lexicallyChainedTo repair of DNA double-strand breaks,recombinational

craft-sa-dev

Id Subject Object Predicate Lexical cue
T36 0-5 NN denotes BRCA2
T37 0-34 sentence denotes BRCA2 and homologous recombination
T38 6-9 CC denotes and
T39 10-20 JJ denotes homologous
T40 21-34 NN denotes recombination
T41 34-35 sentence denotes
T42 45-166 sentence denotes Two recent papers provide new evidence relevant to the role of the breast cancer susceptibility gene BRCA2 in DNA repair.
T43 45-48 CD denotes Two
T44 56-62 NNS denotes papers
T45 49-55 JJ denotes recent
T46 63-70 VBP denotes provide
T47 71-74 JJ denotes new
T48 75-83 NN denotes evidence
T49 84-92 JJ denotes relevant
T50 93-95 IN denotes to
T51 96-99 DT denotes the
T52 100-104 NN denotes role
T53 105-107 IN denotes of
T54 108-111 DT denotes the
T55 141-145 NN denotes gene
T56 112-118 NN denotes breast
T57 119-125 NN denotes cancer
T58 126-140 NN denotes susceptibility
T59 146-151 NN denotes BRCA2
T60 152-154 IN denotes in
T61 155-158 NN denotes DNA
T62 159-165 NN denotes repair
T63 165-166 . denotes .
T64 166-313 sentence denotes Moynahan et al provide genetic data indicating a requirement for BRCA2 in homology-dependent (recombinational) repair of DNA double-strand breaks.
T65 167-175 NNP denotes Moynahan
T66 182-189 VBP denotes provide
T67 176-178 FW denotes et
T68 179-181 FW denotes al
T69 190-197 JJ denotes genetic
T70 198-202 NNS denotes data
T71 203-213 VBG denotes indicating
T72 214-215 DT denotes a
T73 216-227 NN denotes requirement
T74 228-231 IN denotes for
T75 232-237 NN denotes BRCA2
T76 238-240 IN denotes in
T77 241-249 JJ denotes homology
T78 250-259 JJ denotes dependent
T79 249-250 HYPH denotes -
T80 261-276 JJ denotes recombinational
T81 260-261 -LRB- denotes (
T82 278-284 NN denotes repair
T83 276-277 -RRB- denotes )
T84 285-287 IN denotes of
T85 288-291 NN denotes DNA
T86 306-312 NNS denotes breaks
T87 292-298 JJ denotes double
T88 299-305 NN denotes strand
T89 298-299 HYPH denotes -
T90 312-313 . denotes .
T91 313-450 sentence denotes The second paper, by Davies et al, begins to address the mechanism through which BRCA2 makes its contribution to recombinational repair.
T92 314-317 DT denotes The
T93 325-330 NN denotes paper
T94 318-324 JJ denotes second
T95 349-355 VBZ denotes begins
T96 330-332 , denotes ,
T97 332-334 IN denotes by
T98 335-341 NNP denotes Davies
T99 342-344 FW denotes et
T100 345-347 FW denotes al
T101 347-349 , denotes ,
T102 356-358 TO denotes to
T103 359-366 VB denotes address
T104 367-370 DT denotes the
T105 371-380 NN denotes mechanism
T106 381-388 IN denotes through
T107 401-406 VBZ denotes makes
T108 389-394 WDT denotes which
T109 395-400 NN denotes BRCA2
T110 407-410 PRP$ denotes its
T111 411-423 NN denotes contribution
T112 424-426 IN denotes to
T113 427-442 JJ denotes recombinational
T114 443-449 NN denotes repair
T115 449-450 . denotes .
T116 450-563 sentence denotes BRCA2 appears to function in recombination via interactions with the major eukaryotic recombinase RAD51 [1,2,3].
T117 451-456 NN denotes BRCA2
T118 457-464 VBZ denotes appears
T119 465-467 TO denotes to
T120 468-476 VB denotes function
T121 477-479 IN denotes in
T122 480-493 NN denotes recombination
T123 494-497 IN denotes via
T124 498-510 NNS denotes interactions
T125 511-515 IN denotes with
T126 516-519 DT denotes the
T127 537-548 NN denotes recombinase
T128 520-525 JJ denotes major
T129 526-536 JJ denotes eukaryotic
T130 549-554 NN denotes RAD51
T131 555-556 -LRB- denotes [
T132 560-561 CD denotes 3
T133 556-557 CD denotes 1
T134 557-558 , denotes ,
T135 558-559 CD denotes 2
T136 559-560 , denotes ,
T137 561-562 -RRB- denotes ]
T138 562-563 . denotes .
T139 563-763 sentence denotes We briefly review the context in which the two studies were carried out, we comment on the results presented, and we discuss models designed to account for the role of BRCA2 in RAD51–mediated repair.
T140 564-566 PRP denotes We
T141 575-581 VBP denotes review
T142 567-574 RB denotes briefly
T143 582-585 DT denotes the
T144 586-593 NN denotes context
T145 594-596 IN denotes in
T146 624-631 VBN denotes carried
T147 597-602 WDT denotes which
T148 603-606 DT denotes the
T149 611-618 NNS denotes studies
T150 607-610 CD denotes two
T151 619-623 VBD denotes were
T152 632-635 RP denotes out
T153 635-637 , denotes ,
T154 637-639 PRP denotes we
T155 640-647 VBP denotes comment
T156 648-650 IN denotes on
T157 651-654 DT denotes the
T158 655-662 NNS denotes results
T159 663-672 VBN denotes presented
T160 672-674 , denotes ,
T161 674-677 CC denotes and
T162 678-680 PRP denotes we
T163 681-688 VBP denotes discuss
T164 689-695 NNS denotes models
T165 696-704 VBN denotes designed
T166 705-707 TO denotes to
T167 708-715 VB denotes account
T168 716-719 IN denotes for
T169 720-723 DT denotes the
T170 724-728 NN denotes role
T171 729-731 IN denotes of
T172 732-737 NN denotes BRCA2
T173 738-740 IN denotes in
T174 741-746 NN denotes RAD51
T175 747-755 VBN denotes mediated
T176 746-747 HYPH denotes –
T177 756-762 NN denotes repair
T178 762-763 . denotes .
T227 771-776 NN denotes BRCA2
T228 777-780 VBD denotes was
T229 781-784 DT denotes the
T230 821-825 NN denotes gene
T231 785-791 JJ denotes second
T232 792-798 NN denotes breast
T233 799-805 NN denotes cancer
T234 806-820 NN denotes susceptibility
T235 826-828 TO denotes to
T236 832-842 VBN denotes discovered
T237 829-831 VB denotes be
T238 842-844 , denotes ,
T239 844-847 CC denotes and
T240 848-851 VBD denotes was
T241 852-860 VBN denotes isolated
T242 861-868 IN denotes through
T243 869-879 JJ denotes positional
T244 880-887 NN denotes cloning
T245 888-893 VBG denotes using
T246 894-898 NNS denotes data
T247 899-903 IN denotes from
T248 904-912 NNS denotes families
T249 913-917 IN denotes with
T250 918-927 JJ denotes inherited
T251 935-941 NN denotes cancer
T252 928-934 NN denotes breast
T253 942-943 -LRB- denotes [
T254 943-944 CD denotes 4
T255 944-945 -RRB- denotes ]
T256 945-946 . denotes .
T257 946-1083 sentence denotes Cells with mutant BRCA2 protein are, like many cancer cells, genetically unstable and accumulate gross chromosomal rearrangements [5,6].
T258 947-952 NNS denotes Cells
T259 979-982 VBP denotes are
T260 953-957 IN denotes with
T261 958-964 JJ denotes mutant
T262 971-978 NN denotes protein
T263 965-970 NN denotes BRCA2
T264 982-984 , denotes ,
T265 984-988 IN denotes like
T266 989-993 JJ denotes many
T267 1001-1006 NNS denotes cells
T268 994-1000 NN denotes cancer
T269 1006-1008 , denotes ,
T270 1008-1019 RB denotes genetically
T271 1020-1028 JJ denotes unstable
T272 1029-1032 CC denotes and
T273 1033-1043 VBP denotes accumulate
T274 1044-1049 JJ denotes gross
T275 1062-1076 NNS denotes rearrangements
T276 1050-1061 JJ denotes chromosomal
T277 1077-1078 -LRB- denotes [
T278 1080-1081 CD denotes 6
T279 1078-1079 CD denotes 5
T280 1079-1080 , denotes ,
T281 1081-1082 -RRB- denotes ]
T282 1082-1083 . denotes .
T284 1084-1087 DT denotes The
T285 1088-1096 NN denotes sequence
T286 1138-1144 VBZ denotes offers
T287 1097-1099 IN denotes of
T288 1100-1104 DT denotes this
T289 1111-1118 NN denotes protein
T290 1105-1110 JJ denotes large
T291 1119-1120 -LRB- denotes (
T292 1120-1124 CD denotes 3418
T293 1131-1136 NNS denotes acids
T294 1125-1130 NN denotes amino
T295 1136-1137 -RRB- denotes )
T296 1145-1149 RB denotes very
T297 1157-1161 NN denotes clue
T298 1150-1156 JJ denotes little
T299 1162-1164 IN denotes to
T300 1165-1168 PRP$ denotes its
T301 1169-1177 NN denotes function
T302 1177-1179 , denotes ,
T303 1179-1187 IN denotes although
R13 T51 T52 det the,role
R14 T52 T50 pobj role,to
R15 T53 T52 prep of,role
R16 T54 T55 det the,gene
R17 T55 T53 pobj gene,of
R18 T56 T57 compound breast,cancer
R19 T57 T58 compound cancer,susceptibility
R20 T58 T55 compound susceptibility,gene
R21 T59 T55 appos BRCA2,gene
R22 T60 T52 prep in,role
R23 T61 T62 compound DNA,repair
R24 T62 T60 pobj repair,in
R25 T63 T46 punct .,provide
R26 T65 T66 nsubj Moynahan,provide
R27 T67 T68 advmod et,al
R28 T68 T65 advmod al,Moynahan
R29 T69 T70 amod genetic,data
R30 T70 T66 dobj data,provide
R31 T71 T70 acl indicating,data
R32 T72 T73 det a,requirement
R33 T73 T71 dobj requirement,indicating
R34 T74 T73 prep for,requirement
R35 T75 T74 pobj BRCA2,for
R36 T76 T73 prep in,requirement
R37 T77 T78 amod homology,dependent
R38 T78 T80 amod dependent,recombinational
R39 T79 T78 punct -,dependent
R40 T80 T82 amod recombinational,repair
R41 T81 T80 punct (,recombinational
R42 T82 T76 pobj repair,in
R43 T83 T82 punct ),repair
R44 T84 T82 prep of,repair
R45 T85 T86 nmod DNA,breaks
R46 T86 T84 pobj breaks,of
R47 T87 T88 amod double,strand
R48 T88 T86 compound strand,breaks
R49 T89 T88 punct -,strand
R50 T90 T66 punct .,provide
R51 T92 T93 det The,paper
R52 T93 T95 nsubj paper,begins
R53 T94 T93 amod second,paper
R54 T96 T93 punct ", ",paper
R55 T97 T93 prep by,paper
R56 T98 T97 pobj Davies,by
R57 T99 T100 advmod et,al
R58 T100 T98 advmod al,Davies
R59 T101 T95 punct ", ",begins
R60 T102 T103 aux to,address
R61 T103 T95 xcomp address,begins
R62 T104 T105 det the,mechanism
R63 T105 T103 dobj mechanism,address
R64 T106 T107 prep through,makes
R66 T108 T106 pobj which,through
R67 T109 T107 nsubj BRCA2,makes
R68 T110 T111 poss its,contribution
R69 T111 T107 dobj contribution,makes
R70 T112 T111 prep to,contribution
R71 T113 T114 amod recombinational,repair
R72 T114 T112 pobj repair,to
R73 T115 T95 punct .,begins
R74 T117 T118 nsubj BRCA2,appears
R75 T119 T120 aux to,function
R76 T120 T118 xcomp function,appears
R77 T121 T120 prep in,function
R78 T122 T121 pobj recombination,in
R79 T123 T120 prep via,function
R80 T124 T123 pobj interactions,via
R81 T125 T124 prep with,interactions
R82 T126 T127 det the,recombinase
R84 T128 T127 amod major,recombinase
R85 T129 T127 amod eukaryotic,recombinase
R86 T130 T127 appos RAD51,recombinase
R87 T131 T132 punct [,3
R88 T132 T118 parataxis 3,appears
R89 T133 T132 nummod 1,3
R90 T134 T132 punct ",",3
R91 T135 T132 nummod 2,3
R92 T136 T132 punct ",",3
R93 T137 T132 punct ],3
R94 T138 T118 punct .,appears
R95 T140 T141 nsubj We,review
R96 T142 T141 advmod briefly,review
R97 T143 T144 det the,context
R98 T144 T141 dobj context,review
R99 T145 T146 prep in,carried
R100 T146 T144 relcl carried,context
R101 T147 T145 pobj which,in
R102 T148 T149 det the,studies
R103 T149 T146 nsubjpass studies,carried
R104 T150 T149 nummod two,studies
R105 T151 T146 auxpass were,carried
R106 T152 T146 prt out,carried
R107 T153 T141 punct ", ",review
R108 T154 T155 nsubj we,comment
R109 T155 T141 conj comment,review
R110 T156 T155 prep on,comment
R111 T157 T158 det the,results
R112 T158 T156 pobj results,on
R113 T159 T158 acl presented,results
R114 T160 T155 punct ", ",comment
R115 T161 T155 cc and,comment
R116 T162 T163 nsubj we,discuss
R117 T163 T155 conj discuss,comment
R118 T164 T163 dobj models,discuss
R119 T165 T164 acl designed,models
R120 T166 T167 aux to,account
R121 T167 T165 advcl account,designed
R122 T168 T167 prep for,account
R123 T169 T170 det the,role
R124 T170 T168 pobj role,for
R125 T171 T170 prep of,role
R126 T172 T171 pobj BRCA2,of
R127 T173 T170 prep in,role
R128 T174 T175 npadvmod RAD51,mediated
R129 T175 T177 amod mediated,repair
R130 T176 T175 punct –,mediated
R131 T177 T173 pobj repair,in
R132 T178 T163 punct .,discuss
R154 T247 T246 prep from,data
R155 T248 T247 pobj families,from
R156 T249 T248 prep with,families
R157 T250 T251 amod inherited,cancer
R158 T251 T249 pobj cancer,with
R159 T252 T251 compound breast,cancer
R160 T253 T254 punct [,4
R161 T254 T241 parataxis 4,isolated
R162 T255 T254 punct ],4
R163 T256 T228 punct .,was
R164 T258 T259 nsubj Cells,are
R165 T260 T258 prep with,Cells
R166 T261 T262 amod mutant,protein
R167 T262 T260 pobj protein,with
R168 T263 T262 compound BRCA2,protein
R169 T264 T259 punct ", ",are
R170 T265 T259 prep like,are
R171 T266 T267 amod many,cells
R172 T267 T265 pobj cells,like
R173 T268 T267 compound cancer,cells
R174 T269 T259 punct ", ",are
R175 T270 T271 advmod genetically,unstable
R176 T271 T259 acomp unstable,are
R177 T272 T259 cc and,are
R178 T273 T259 conj accumulate,are
R179 T274 T275 amod gross,rearrangements
R180 T275 T273 dobj rearrangements,accumulate
R181 T276 T275 amod chromosomal,rearrangements
R182 T277 T278 punct [,6
R183 T278 T273 parataxis 6,accumulate
R184 T279 T278 nummod 5,6
R185 T280 T278 punct ",",6
R186 T281 T278 punct ],6
R187 T282 T259 punct .,are
R188 T284 T285 det The,sequence
R189 T285 T286 nsubj sequence,offers
R190 T287 T285 prep of,sequence
R191 T288 T289 det this,protein
R192 T289 T287 pobj protein,of
R193 T290 T289 amod large,protein
R194 T291 T285 punct (,sequence
R195 T292 T293 nummod 3418,acids
R135 T227 T228 nsubj BRCA2,was
R136 T229 T230 det the,gene
R137 T230 T228 attr gene,was
R138 T231 T230 amod second,gene
R139 T232 T233 compound breast,cancer
R140 T233 T234 compound cancer,susceptibility
R141 T234 T230 compound susceptibility,gene
R142 T235 T236 aux to,discovered
R143 T236 T230 advcl discovered,gene
R144 T237 T236 auxpass be,discovered
R145 T238 T228 punct ", ",was
R146 T239 T228 cc and,was
R147 T240 T241 auxpass was,isolated
R148 T241 T228 conj isolated,was
R149 T242 T241 prep through,isolated
R150 T243 T244 amod positional,cloning
R151 T244 T242 pobj cloning,through
R152 T245 T241 advcl using,isolated
R153 T246 T245 dobj data,using
R196 T293 T285 appos acids,sequence
R197 T294 T293 compound amino,acids
R198 T295 T286 punct ),offers
R199 T296 T297 advmod very,clue
R200 T297 T286 dobj clue,offers
R201 T298 T297 amod little,clue
R202 T299 T297 prep to,clue
R203 T300 T301 poss its,function
R204 T301 T299 pobj function,to
R205 T302 T286 punct ", ",offers
R3 T38 T36 cc and,BRCA2
R4 T39 T40 amod homologous,recombination
R5 T40 T36 conj recombination,BRCA2
R6 T43 T44 nummod Two,papers
R7 T44 T46 nsubj papers,provide
R8 T45 T44 amod recent,papers
R9 T47 T48 amod new,evidence
R10 T48 T46 dobj evidence,provide
R11 T49 T48 amod relevant,evidence
R12 T50 T49 prep to,relevant
R65 T107 T105 relcl makes,mechanism
R83 T127 T125 pobj recombinase,with