PMC:1382200 / 294-508 JSONTXT

{"project":"craft-sa-dev","denotations":[{"id":"T714","span":{"begin":1,"end":9},"obj":"JJ"},{"id":"T715","span":{"begin":20,"end":28},"obj":"NNS"},{"id":"T716","span":{"begin":10,"end":19},"obj":"JJ"},{"id":"T717","span":{"begin":28,"end":30},"obj":","},{"id":"T718","span":{"begin":30,"end":37},"obj":"VBN"},{"id":"T719","span":{"begin":38,"end":40},"obj":"IN"},{"id":"T720","span":{"begin":41,"end":46},"obj":"NN"},{"id":"T721","span":{"begin":47,"end":48},"obj":"-LRB-"},{"id":"T722","span":{"begin":48,"end":49},"obj":"NN"},{"id":"T723","span":{"begin":50,"end":57},"obj":"NN"},{"id":"T724","span":{"begin":49,"end":50},"obj":"HYPH"},{"id":"T725","span":{"begin":57,"end":58},"obj":"-RRB-"},{"id":"T726","span":{"begin":59,"end":61},"obj":"CC"},{"id":"T727","span":{"begin":62,"end":67},"obj":"NN"},{"id":"T728","span":{"begin":68,"end":69},"obj":"-LRB-"},{"id":"T729","span":{"begin":69,"end":70},"obj":"NN"},{"id":"T730","span":{"begin":71,"end":78},"obj":"NN"},{"id":"T731","span":{"begin":70,"end":71},"obj":"HYPH"},{"id":"T732","span":{"begin":78,"end":79},"obj":"-RRB-"},{"id":"T733","span":{"begin":79,"end":81},"obj":","},{"id":"T734","span":{"begin":81,"end":84},"obj":"CC"},{"id":"T735","span":{"begin":85,"end":86},"obj":"DT"},{"id":"T736","span":{"begin":105,"end":112},"obj":"NN"},{"id":"T737","span":{"begin":87,"end":93},"obj":"JJ"},{"id":"T738","span":{"begin":94,"end":104},"obj":"JJ"},{"id":"T739","span":{"begin":113,"end":120},"obj":"VBN"},{"id":"T740","span":{"begin":121,"end":123},"obj":"IN"},{"id":"T741","span":{"begin":124,"end":129},"obj":"NN"},{"id":"T742","span":{"begin":129,"end":130},"obj":"."},{"id":"T744","span":{"begin":131,"end":141},"obj":"NN"},{"id":"T745","span":{"begin":166,"end":175},"obj":"VBD"},{"id":"T746","span":{"begin":142,"end":144},"obj":"IN"},{"id":"T747","span":{"begin":145,"end":148},"obj":"DT"},{"id":"T748","span":{"begin":161,"end":165},"obj":"NN"},{"id":"T749","span":{"begin":149,"end":154},"obj":"NN"},{"id":"T750","span":{"begin":155,"end":160},"obj":"NN"},{"id":"T751","span":{"begin":176,"end":180},"obj":"CC"},{"id":"T752","span":{"begin":183,"end":190},"obj":"NN"},{"id":"T753","span":{"begin":181,"end":182},"obj":"NN"},{"id":"T754","span":{"begin":182,"end":183},"obj":"HYPH"},{"id":"T755","span":{"begin":205,"end":213},"obj":"NN"},{"id":"T756","span":{"begin":191,"end":194},"obj":"CC"},{"id":"T757","span":{"begin":195,"end":196},"obj":"NN"},{"id":"T758","span":{"begin":197,"end":204},"obj":"NN"},{"id":"T759","span":{"begin":196,"end":197},"obj":"HYPH"}],"relations":[{"id":"R73","pred":"det","subj":"T747","obj":"T748"},{"id":"R74","pred":"pobj","subj":"T748","obj":"T746"},{"id":"R42","pred":"amod","subj":"T714","obj":"T715"},{"id":"R44","pred":"amod","subj":"T716","obj":"T715"},{"id":"R45","pred":"punct","subj":"T717","obj":"T715"},{"id":"R46","pred":"acl","subj":"T718","obj":"T715"},{"id":"R47","pred":"agent","subj":"T719","obj":"T718"},{"id":"R48","pred":"pobj","subj":"T720","obj":"T719"},{"id":"R49","pred":"punct","subj":"T721","obj":"T720"},{"id":"R50","pred":"compound","subj":"T722","obj":"T723"},{"id":"R52","pred":"punct","subj":"T724","obj":"T723"},{"id":"R53","pred":"punct","subj":"T725","obj":"T720"},{"id":"R54","pred":"cc","subj":"T726","obj":"T720"},{"id":"R55","pred":"conj","subj":"T727","obj":"T720"},{"id":"R56","pred":"punct","subj":"T728","obj":"T727"},{"id":"R57","pred":"compound","subj":"T729","obj":"T730"},{"id":"R59","pred":"punct","subj":"T731","obj":"T730"},{"id":"R60","pred":"punct","subj":"T732","obj":"T715"},{"id":"R61","pred":"punct","subj":"T733","obj":"T715"},{"id":"R62","pred":"cc","subj":"T734","obj":"T715"},{"id":"R63","pred":"det","subj":"T735","obj":"T736"},{"id":"R64","pred":"conj","subj":"T736","obj":"T715"},{"id":"R65","pred":"amod","subj":"T737","obj":"T736"},{"id":"R66","pred":"amod","subj":"T738","obj":"T736"},{"id":"R67","pred":"acl","subj":"T739","obj":"T736"},{"id":"R68","pred":"agent","subj":"T740","obj":"T739"},{"id":"R69","pred":"pobj","subj":"T741","obj":"T740"},{"id":"R71","pred":"nsubj","subj":"T744","obj":"T745"},{"id":"R72","pred":"prep","subj":"T746","obj":"T744"},{"id":"R75","pred":"compound","subj":"T749","obj":"T748"},{"id":"R76","pred":"compound","subj":"T750","obj":"T748"},{"id":"R77","pred":"preconj","subj":"T751","obj":"T752"},{"id":"R78","pred":"nmod","subj":"T752","obj":"T755"},{"id":"R79","pred":"nmod","subj":"T753","obj":"T752"},{"id":"R80","pred":"punct","subj":"T754","obj":"T752"},{"id":"R81","pred":"dobj","subj":"T755","obj":"T745"},{"id":"R82","pred":"cc","subj":"T756","obj":"T752"},{"id":"R83","pred":"compound","subj":"T757","obj":"T758"},{"id":"R84","pred":"conj","subj":"T758","obj":"T752"},{"id":"R85","pred":"punct","subj":"T759","obj":"T758"},{"id":"R51","pred":"appos","subj":"T723","obj":"T720"},{"id":"R58","pred":"appos","subj":"T730","obj":"T727"}],"text":" distinct catalytic subunits, encoded by Capn1 (μ-calpain) or Capn2 (m-calpain), and a common regulatory subunit encoded by Capn4. Disruption of the mouse Capn4 gene abolished both μ-calpain and m-calpain activity,"}

{"project":"craft-ca-core-dev","denotations":[{"id":"T541","span":{"begin":41,"end":46},"obj":"PR:000005009"},{"id":"T542","span":{"begin":62,"end":67},"obj":"PR:000005015"},{"id":"T543","span":{"begin":94,"end":104},"obj":"GO:0065007"},{"id":"T544","span":{"begin":124,"end":129},"obj":"PR:000005022"},{"id":"T545","span":{"begin":149,"end":154},"obj":"NCBITaxon:10088"},{"id":"T546","span":{"begin":155,"end":160},"obj":"PR:000005022"},{"id":"T547","span":{"begin":161,"end":165},"obj":"SO:0000704"}],"text":" distinct catalytic subunits, encoded by Capn1 (μ-calpain) or Capn2 (m-calpain), and a common regulatory subunit encoded by Capn4. Disruption of the mouse Capn4 gene abolished both μ-calpain and m-calpain activity,"}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T599","span":{"begin":10,"end":19},"obj":"GO_MOP_EXT:catalysis"},{"id":"T600","span":{"begin":30,"end":37},"obj":"SO_EXT:sequence_coding_function"},{"id":"T601","span":{"begin":41,"end":46},"obj":"PR_EXT:000005009"},{"id":"T602","span":{"begin":48,"end":57},"obj":"GO_PR_EXT:calpain_1_complex"},{"id":"T603","span":{"begin":62,"end":67},"obj":"PR_EXT:000005015"},{"id":"T604","span":{"begin":69,"end":78},"obj":"GO_PR_EXT:calpain_2_complex"},{"id":"T605","span":{"begin":94,"end":104},"obj":"GO:0065007"},{"id":"T606","span":{"begin":113,"end":120},"obj":"SO_EXT:sequence_coding_function"},{"id":"T607","span":{"begin":124,"end":129},"obj":"PR_EXT:000005022"},{"id":"T608","span":{"begin":149,"end":154},"obj":"NCBITaxon:10088"},{"id":"T609","span":{"begin":155,"end":160},"obj":"PR_EXT:000005022"},{"id":"T610","span":{"begin":161,"end":165},"obj":"SO_EXT:0000704"},{"id":"T611","span":{"begin":181,"end":190},"obj":"GO_PR_EXT:calpain_1_complex"},{"id":"T612","span":{"begin":195,"end":204},"obj":"GO_PR_EXT:calpain_2_complex"}],"text":" distinct catalytic subunits, encoded by Capn1 (μ-calpain) or Capn2 (m-calpain), and a common regulatory subunit encoded by Capn4. Disruption of the mouse Capn4 gene abolished both μ-calpain and m-calpain activity,"}