> top > docs > PMC:1382200 > spans > 28860-29545 > annotations

PMC:1382200 / 28860-29545 JSONTXT

Annnotations TAB JSON ListView MergeView

craft-sa-dev

Id Subject Object Predicate Lexical cue
T15551 666-675 NN denotes targeting
T15550 661-665 NN denotes gene
T15549 649-660 JJ denotes conditional
T15548 676-684 NN denotes strategy
T15547 647-648 DT denotes a
T15546 641-646 VBG denotes using
T15545 628-630 VB denotes be
T15544 631-640 VBN denotes addressed
T15543 625-627 TO denotes to
T15542 620-624 VB denotes have
T15541 615-619 MD denotes will
T15540 611-614 CC denotes and
T15539 597-599 VB denotes be
T15538 600-610 VBN denotes elucidated
T15537 594-596 TO denotes to
T15536 582-586 NNS denotes mice
T15535 576-581 JJ denotes adult
T15534 573-575 IN denotes in
T15533 569-572 CC denotes and
T15532 555-568 NN denotes embryogenesis
T15531 537-554 JJ denotes post-implantation
T15530 530-536 IN denotes during
T15529 521-522 HYPH denotes -
T15528 522-529 NN denotes calpain
T15527 520-521 NN denotes m
T15526 517-519 IN denotes of
T15525 587-593 VBP denotes remain
T15524 507-516 NNS denotes functions
T15523 503-506 DT denotes The
T15522 502-685 sentence denotes The functions of m-calpain during post-implantation embryogenesis and in adult mice remain to be elucidated and will have to be addressed using a conditional gene targeting strategy.
T15521 501-502 . denotes .
T15520 497-501 FW denotes vivo
T15519 494-496 FW denotes in
T15518 479-487 JJ denotes distinct
T15517 488-493 NNS denotes roles
T15516 474-478 DT denotes some
T15515 461-468 RB denotes clearly
T15514 448-451 CD denotes two
T15513 452-460 NNS denotes isoforms
T15512 444-447 DT denotes the
T15511 469-473 VBP denotes have
T15510 439-443 IN denotes that
T15509 425-438 VBG denotes demonstrating
T15508 423-425 , denotes ,
T15507 415-416 HYPH denotes -
T15506 414-415 NN denotes m
T15505 410-413 CC denotes and
T15504 408-409 HYPH denotes -
T15503 416-423 NN denotes calpain
T15502 407-408 NN denotes μ
T15501 404-406 IN denotes of
T15500 385-390 FW denotes vitro
T15499 382-384 FW denotes in
T15498 373-381 JJ denotes apparent
T15497 391-403 NNS denotes similarities
T15496 369-372 DT denotes the
T15495 361-368 IN denotes despite
T15494 352-353 HYPH denotes -
T15493 353-360 NN denotes calpain
T15492 351-352 NN denotes μ
T15491 348-350 IN denotes by
T15490 344-347 RP denotes out
T15489 333-335 VB denotes be
T15488 329-332 RB denotes not
T15487 326-329 MD denotes can
T15486 317-325 NN denotes function
T15485 312-316 DT denotes this
T15484 310-312 , denotes ,
T15483 336-343 VBN denotes carried
T15482 299-310 RB denotes Furthermore
T15481 298-502 sentence denotes Furthermore, this function cannot be carried out by μ-calpain despite the apparent in vitro similarities of μ- and m-calpain, demonstrating that the two isoforms clearly have some distinct roles in vivo.
T15480 297-298 . denotes .
T15479 286-297 NN denotes development
T15478 269-285 JJ denotes pre-implantation
T15477 266-268 IN denotes to
T15476 258-265 VBN denotes related
T15475 249-257 RB denotes possibly
T15474 247-249 , denotes ,
T15473 234-247 NN denotes embryogenesis
T15472 227-233 JJ denotes murine
T15471 224-226 IN denotes in
T15470 205-218 JJ denotes indispensable
T15469 219-223 NN denotes role
T15468 202-204 DT denotes an
T15467 187-188 HYPH denotes -
T15466 188-195 NN denotes calpain
T15465 186-187 NN denotes m
T15464 196-201 VBZ denotes plays
T15463 181-185 IN denotes that
T15462 166-169 VBD denotes was
T15461 163-165 PRP denotes it
T15460 161-163 , denotes ,
T15459 170-180 VBN denotes determined
T15458 154-161 RB denotes Firstly
T15457 153-298 sentence denotes Firstly, it was determined that m-calpain plays an indispensable role in murine embryogenesis, possibly related to pre-implantation development.
T15456 152-153 . denotes .
T15455 144-145 HYPH denotes -
T15454 143-144 NN denotes m
T15453 139-142 CC denotes and
T15452 137-138 HYPH denotes -
T15451 145-152 NN denotes calpain
T15450 136-137 NN denotes μ
T15449 134-136 , denotes ,
T15448 118-125 NN denotes calpain
T15447 107-117 JJ denotes ubiquitous
T15446 103-106 CD denotes two
T15445 126-134 NNS denotes isoforms
T15444 99-102 DT denotes the
T15443 96-98 IN denotes of
T15442 76-89 JJ denotes physiological
T15441 90-95 NNS denotes roles
T15440 72-75 DT denotes the
T15439 62-71 VBG denotes regarding
T15438 42-51 JJ denotes important
T15437 52-61 NNS denotes questions
T15436 38-41 CD denotes two
T15435 24-27 VBZ denotes has
T15434 19-23 RB denotes here
T15433 9-18 VBN denotes presented
T15432 28-37 VBN denotes clarified
T15431 4-8 NN denotes work
T15430 0-3 DT denotes The
T15552 684-685 . denotes .
R4589 T15430 T15431 det The,work
R4590 T15431 T15432 nsubj work,clarified
R4591 T15433 T15431 acl presented,work
R4592 T15434 T15433 advmod here,presented
R4593 T15435 T15432 aux has,clarified
R4594 T15436 T15437 nummod two,questions
R4595 T15437 T15432 dobj questions,clarified
R4596 T15438 T15437 amod important,questions
R4597 T15439 T15437 prep regarding,questions
R4598 T15440 T15441 det the,roles
R4599 T15441 T15439 pobj roles,regarding
R4600 T15442 T15441 amod physiological,roles
R4601 T15443 T15441 prep of,roles
R4602 T15444 T15445 det the,isoforms
R4603 T15445 T15443 pobj isoforms,of
R4604 T15446 T15445 nummod two,isoforms
R4605 T15447 T15445 amod ubiquitous,isoforms
R4606 T15448 T15445 compound calpain,isoforms
R4607 T15449 T15445 punct ", ",isoforms
R4608 T15450 T15451 nmod μ,calpain
R4609 T15451 T15445 appos calpain,isoforms
R4610 T15452 T15450 punct -,μ
R4611 T15453 T15450 cc and,μ
R4612 T15454 T15450 conj m,μ
R4613 T15455 T15451 punct -,calpain
R4614 T15456 T15432 punct .,clarified
R4615 T15458 T15459 advmod Firstly,determined
R4616 T15460 T15459 punct ", ",determined
R4617 T15461 T15459 nsubjpass it,determined
R4618 T15462 T15459 auxpass was,determined
R4619 T15463 T15464 mark that,plays
R4620 T15464 T15459 ccomp plays,determined
R4621 T15465 T15466 compound m,calpain
R4622 T15466 T15464 nsubj calpain,plays
R4623 T15467 T15466 punct -,calpain
R4624 T15468 T15469 det an,role
R4625 T15469 T15464 dobj role,plays
R4626 T15470 T15469 amod indispensable,role
R4627 T15471 T15469 prep in,role
R4628 T15472 T15473 amod murine,embryogenesis
R4629 T15473 T15471 pobj embryogenesis,in
R4630 T15474 T15469 punct ", ",role
R4631 T15475 T15476 advmod possibly,related
R4632 T15476 T15469 acl related,role
R4633 T15477 T15476 prep to,related
R4634 T15478 T15479 amod pre-implantation,development
R4635 T15479 T15477 pobj development,to
R4636 T15480 T15459 punct .,determined
R4637 T15482 T15483 advmod Furthermore,carried
R4638 T15484 T15483 punct ", ",carried
R4639 T15485 T15486 det this,function
R4640 T15486 T15483 nsubjpass function,carried
R4641 T15487 T15483 aux can,carried
R4642 T15488 T15483 neg not,carried
R4643 T15489 T15483 auxpass be,carried
R4644 T15490 T15483 prt out,carried
R4645 T15491 T15483 agent by,carried
R4646 T15492 T15493 compound μ,calpain
R4647 T15493 T15491 pobj calpain,by
R4648 T15494 T15493 punct -,calpain
R4649 T15495 T15483 prep despite,carried
R4650 T15496 T15497 det the,similarities
R4651 T15497 T15495 pobj similarities,despite
R4652 T15498 T15497 amod apparent,similarities
R4653 T15499 T15500 advmod in,vitro
R4654 T15500 T15497 amod vitro,similarities
R4655 T15501 T15497 prep of,similarities
R4656 T15502 T15503 nmod μ,calpain
R4657 T15503 T15501 pobj calpain,of
R4658 T15504 T15502 punct -,μ
R4659 T15505 T15502 cc and,μ
R4660 T15506 T15502 conj m,μ
R4661 T15507 T15503 punct -,calpain
R4662 T15508 T15483 punct ", ",carried
R4663 T15509 T15483 advcl demonstrating,carried
R4664 T15510 T15511 mark that,have
R4665 T15511 T15509 ccomp have,demonstrating
R4666 T15512 T15513 det the,isoforms
R4667 T15513 T15511 nsubj isoforms,have
R4668 T15514 T15513 nummod two,isoforms
R4669 T15515 T15511 advmod clearly,have
R4670 T15516 T15517 det some,roles
R4671 T15517 T15511 dobj roles,have
R4672 T15518 T15517 amod distinct,roles
R4673 T15519 T15520 advmod in,vivo
R4674 T15520 T15511 advmod vivo,have
R4675 T15521 T15483 punct .,carried
R4676 T15523 T15524 det The,functions
R4677 T15524 T15525 nsubj functions,remain
R4678 T15526 T15524 prep of,functions
R4679 T15527 T15528 compound m,calpain
R4680 T15528 T15526 pobj calpain,of
R4681 T15529 T15528 punct -,calpain
R4682 T15530 T15524 prep during,functions
R4683 T15531 T15532 amod post-implantation,embryogenesis
R4684 T15532 T15530 pobj embryogenesis,during
R4685 T15533 T15530 cc and,during
R4686 T15534 T15530 conj in,during
R4687 T15535 T15536 amod adult,mice
R4688 T15536 T15534 pobj mice,in
R4689 T15537 T15538 aux to,elucidated
R4690 T15538 T15525 xcomp elucidated,remain
R4691 T15539 T15538 auxpass be,elucidated
R4692 T15540 T15525 cc and,remain
R4693 T15541 T15542 aux will,have
R4694 T15542 T15525 conj have,remain
R4695 T15543 T15544 aux to,addressed
R4696 T15544 T15542 xcomp addressed,have
R4697 T15545 T15544 auxpass be,addressed
R4698 T15546 T15544 advcl using,addressed
R4699 T15547 T15548 det a,strategy
R4700 T15548 T15546 dobj strategy,using
R4701 T15549 T15548 amod conditional,strategy
R4702 T15550 T15551 compound gene,targeting
R4703 T15551 T15548 compound targeting,strategy
R4704 T15552 T15525 punct .,remain

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T15402 234-247 GO:0009790 denotes embryogenesis
T15401 227-233 NCBITaxon:39107 denotes murine
T15400 126-134 SO:0001060 denotes isoforms
T15409 661-665 SO:0000704 denotes gene
T15408 582-586 NCBITaxon:10088 denotes mice
T15407 576-581 UBERON:0007023 denotes adult
T15406 555-568 GO:0009790 denotes embryogenesis
T15405 542-554 GO:0007566 denotes implantation
T15404 452-460 SO:0001060 denotes isoforms
T15403 273-285 GO:0007566 denotes implantation

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T15429 661-665 SO_EXT:0000704 denotes gene
T15428 582-586 NCBITaxon:10088 denotes mice
T15427 576-581 UBERON:0007023 denotes adult
T15426 555-568 GO:0009790 denotes embryogenesis
T15425 542-554 GO:0007566 denotes implantation
T15424 520-529 GO_PR_EXT:calpain_2_complex denotes m-calpain
T15423 452-460 SO_EXT:0001060 denotes isoforms
T15422 414-423 GO_PR_EXT:calpain_2_complex denotes m-calpain
T15421 416-423 GO_PR_EXT:calpain_1_complex denotes calpain
T15420 407-409 _FRAGMENT denotes μ-
T15419 351-360 GO_PR_EXT:calpain_1_complex denotes μ-calpain
T15418 273-285 GO:0007566 denotes implantation
T15417 234-247 GO:0009790 denotes embryogenesis
T15416 227-233 NCBITaxon:39107 denotes murine
T15415 186-195 GO_PR_EXT:calpain_2_complex denotes m-calpain
T15414 143-152 GO_PR_EXT:calpain_2_complex denotes m-calpain
T15413 145-152 GO_PR_EXT:calpain_1_complex denotes calpain
T15412 136-138 _FRAGMENT denotes μ-
T15411 126-134 SO_EXT:0001060 denotes isoforms
T15410 76-89 GO_PATO_EXT:physiological_process_or_quality denotes physiological
R4587 T15413 T15412 _lexicallyChainedTo calpain,μ-
R4588 T15421 T15420 _lexicallyChainedTo calpain,μ-