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PMC:1382200 / 28849-29545 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T15551 677-686 NN denotes targeting
T15550 672-676 NN denotes gene
T15549 660-671 JJ denotes conditional
T15548 687-695 NN denotes strategy
T15547 658-659 DT denotes a
T15546 652-657 VBG denotes using
T15545 639-641 VB denotes be
T15544 642-651 VBN denotes addressed
T15543 636-638 TO denotes to
T15542 631-635 VB denotes have
T15541 626-630 MD denotes will
T15540 622-625 CC denotes and
T15539 608-610 VB denotes be
T15538 611-621 VBN denotes elucidated
T15537 605-607 TO denotes to
T15536 593-597 NNS denotes mice
T15535 587-592 JJ denotes adult
T15534 584-586 IN denotes in
T15533 580-583 CC denotes and
T15532 566-579 NN denotes embryogenesis
T15531 548-565 JJ denotes post-implantation
T15530 541-547 IN denotes during
T15529 532-533 HYPH denotes -
T15528 533-540 NN denotes calpain
T15527 531-532 NN denotes m
T15526 528-530 IN denotes of
T15525 598-604 VBP denotes remain
T15524 518-527 NNS denotes functions
T15523 514-517 DT denotes The
T15522 513-696 sentence denotes The functions of m-calpain during post-implantation embryogenesis and in adult mice remain to be elucidated and will have to be addressed using a conditional gene targeting strategy.
T15521 512-513 . denotes .
T15520 508-512 FW denotes vivo
T15519 505-507 FW denotes in
T15518 490-498 JJ denotes distinct
T15517 499-504 NNS denotes roles
T15516 485-489 DT denotes some
T15515 472-479 RB denotes clearly
T15514 459-462 CD denotes two
T15513 463-471 NNS denotes isoforms
T15512 455-458 DT denotes the
T15511 480-484 VBP denotes have
T15510 450-454 IN denotes that
T15509 436-449 VBG denotes demonstrating
T15508 434-436 , denotes ,
T15507 426-427 HYPH denotes -
T15506 425-426 NN denotes m
T15505 421-424 CC denotes and
T15504 419-420 HYPH denotes -
T15503 427-434 NN denotes calpain
T15502 418-419 NN denotes μ
T15501 415-417 IN denotes of
T15500 396-401 FW denotes vitro
T15499 393-395 FW denotes in
T15498 384-392 JJ denotes apparent
T15497 402-414 NNS denotes similarities
T15496 380-383 DT denotes the
T15495 372-379 IN denotes despite
T15494 363-364 HYPH denotes -
T15493 364-371 NN denotes calpain
T15492 362-363 NN denotes μ
T15491 359-361 IN denotes by
T15490 355-358 RP denotes out
T15489 344-346 VB denotes be
T15488 340-343 RB denotes not
T15487 337-340 MD denotes can
T15486 328-336 NN denotes function
T15485 323-327 DT denotes this
T15484 321-323 , denotes ,
T15483 347-354 VBN denotes carried
T15482 310-321 RB denotes Furthermore
T15481 309-513 sentence denotes Furthermore, this function cannot be carried out by μ-calpain despite the apparent in vitro similarities of μ- and m-calpain, demonstrating that the two isoforms clearly have some distinct roles in vivo.
T15480 308-309 . denotes .
T15479 297-308 NN denotes development
T15478 280-296 JJ denotes pre-implantation
T15477 277-279 IN denotes to
T15476 269-276 VBN denotes related
T15475 260-268 RB denotes possibly
T15474 258-260 , denotes ,
T15473 245-258 NN denotes embryogenesis
T15472 238-244 JJ denotes murine
T15471 235-237 IN denotes in
T15470 216-229 JJ denotes indispensable
T15469 230-234 NN denotes role
T15468 213-215 DT denotes an
T15467 198-199 HYPH denotes -
T15466 199-206 NN denotes calpain
T15465 197-198 NN denotes m
T15464 207-212 VBZ denotes plays
T15463 192-196 IN denotes that
T15462 177-180 VBD denotes was
T15461 174-176 PRP denotes it
T15460 172-174 , denotes ,
T15459 181-191 VBN denotes determined
T15458 165-172 RB denotes Firstly
T15457 164-309 sentence denotes Firstly, it was determined that m-calpain plays an indispensable role in murine embryogenesis, possibly related to pre-implantation development.
T15456 163-164 . denotes .
T15455 155-156 HYPH denotes -
T15454 154-155 NN denotes m
T15453 150-153 CC denotes and
T15452 148-149 HYPH denotes -
T15451 156-163 NN denotes calpain
T15450 147-148 NN denotes μ
T15449 145-147 , denotes ,
T15448 129-136 NN denotes calpain
T15447 118-128 JJ denotes ubiquitous
T15446 114-117 CD denotes two
T15445 137-145 NNS denotes isoforms
T15444 110-113 DT denotes the
T15443 107-109 IN denotes of
T15442 87-100 JJ denotes physiological
T15441 101-106 NNS denotes roles
T15440 83-86 DT denotes the
T15439 73-82 VBG denotes regarding
T15438 53-62 JJ denotes important
T15437 63-72 NNS denotes questions
T15436 49-52 CD denotes two
T15435 35-38 VBZ denotes has
T15434 30-34 RB denotes here
T15433 20-29 VBN denotes presented
T15432 39-48 VBN denotes clarified
T15431 15-19 NN denotes work
T15430 11-14 DT denotes The
T15552 695-696 . denotes .
R4589 T15430 T15431 det The,work
R4590 T15431 T15432 nsubj work,clarified
R4591 T15433 T15431 acl presented,work
R4592 T15434 T15433 advmod here,presented
R4593 T15435 T15432 aux has,clarified
R4594 T15436 T15437 nummod two,questions
R4595 T15437 T15432 dobj questions,clarified
R4596 T15438 T15437 amod important,questions
R4597 T15439 T15437 prep regarding,questions
R4598 T15440 T15441 det the,roles
R4599 T15441 T15439 pobj roles,regarding
R4600 T15442 T15441 amod physiological,roles
R4601 T15443 T15441 prep of,roles
R4602 T15444 T15445 det the,isoforms
R4603 T15445 T15443 pobj isoforms,of
R4604 T15446 T15445 nummod two,isoforms
R4605 T15447 T15445 amod ubiquitous,isoforms
R4606 T15448 T15445 compound calpain,isoforms
R4607 T15449 T15445 punct ", ",isoforms
R4608 T15450 T15451 nmod μ,calpain
R4609 T15451 T15445 appos calpain,isoforms
R4610 T15452 T15450 punct -,μ
R4611 T15453 T15450 cc and,μ
R4612 T15454 T15450 conj m,μ
R4613 T15455 T15451 punct -,calpain
R4614 T15456 T15432 punct .,clarified
R4615 T15458 T15459 advmod Firstly,determined
R4616 T15460 T15459 punct ", ",determined
R4617 T15461 T15459 nsubjpass it,determined
R4618 T15462 T15459 auxpass was,determined
R4619 T15463 T15464 mark that,plays
R4620 T15464 T15459 ccomp plays,determined
R4621 T15465 T15466 compound m,calpain
R4622 T15466 T15464 nsubj calpain,plays
R4623 T15467 T15466 punct -,calpain
R4624 T15468 T15469 det an,role
R4625 T15469 T15464 dobj role,plays
R4626 T15470 T15469 amod indispensable,role
R4627 T15471 T15469 prep in,role
R4628 T15472 T15473 amod murine,embryogenesis
R4629 T15473 T15471 pobj embryogenesis,in
R4630 T15474 T15469 punct ", ",role
R4631 T15475 T15476 advmod possibly,related
R4632 T15476 T15469 acl related,role
R4633 T15477 T15476 prep to,related
R4634 T15478 T15479 amod pre-implantation,development
R4635 T15479 T15477 pobj development,to
R4636 T15480 T15459 punct .,determined
R4637 T15482 T15483 advmod Furthermore,carried
R4638 T15484 T15483 punct ", ",carried
R4639 T15485 T15486 det this,function
R4640 T15486 T15483 nsubjpass function,carried
R4641 T15487 T15483 aux can,carried
R4642 T15488 T15483 neg not,carried
R4643 T15489 T15483 auxpass be,carried
R4644 T15490 T15483 prt out,carried
R4645 T15491 T15483 agent by,carried
R4646 T15492 T15493 compound μ,calpain
R4647 T15493 T15491 pobj calpain,by
R4648 T15494 T15493 punct -,calpain
R4649 T15495 T15483 prep despite,carried
R4650 T15496 T15497 det the,similarities
R4651 T15497 T15495 pobj similarities,despite
R4652 T15498 T15497 amod apparent,similarities
R4653 T15499 T15500 advmod in,vitro
R4654 T15500 T15497 amod vitro,similarities
R4655 T15501 T15497 prep of,similarities
R4656 T15502 T15503 nmod μ,calpain
R4657 T15503 T15501 pobj calpain,of
R4658 T15504 T15502 punct -,μ
R4659 T15505 T15502 cc and,μ
R4660 T15506 T15502 conj m,μ
R4661 T15507 T15503 punct -,calpain
R4662 T15508 T15483 punct ", ",carried
R4663 T15509 T15483 advcl demonstrating,carried
R4664 T15510 T15511 mark that,have
R4665 T15511 T15509 ccomp have,demonstrating
R4666 T15512 T15513 det the,isoforms
R4667 T15513 T15511 nsubj isoforms,have
R4668 T15514 T15513 nummod two,isoforms
R4669 T15515 T15511 advmod clearly,have
R4670 T15516 T15517 det some,roles
R4671 T15517 T15511 dobj roles,have
R4672 T15518 T15517 amod distinct,roles
R4673 T15519 T15520 advmod in,vivo
R4674 T15520 T15511 advmod vivo,have
R4675 T15521 T15483 punct .,carried
R4676 T15523 T15524 det The,functions
R4677 T15524 T15525 nsubj functions,remain
R4678 T15526 T15524 prep of,functions
R4679 T15527 T15528 compound m,calpain
R4680 T15528 T15526 pobj calpain,of
R4681 T15529 T15528 punct -,calpain
R4682 T15530 T15524 prep during,functions
R4683 T15531 T15532 amod post-implantation,embryogenesis
R4684 T15532 T15530 pobj embryogenesis,during
R4685 T15533 T15530 cc and,during
R4686 T15534 T15530 conj in,during
R4687 T15535 T15536 amod adult,mice
R4688 T15536 T15534 pobj mice,in
R4689 T15537 T15538 aux to,elucidated
R4690 T15538 T15525 xcomp elucidated,remain
R4691 T15539 T15538 auxpass be,elucidated
R4692 T15540 T15525 cc and,remain
R4693 T15541 T15542 aux will,have
R4694 T15542 T15525 conj have,remain
R4695 T15543 T15544 aux to,addressed
R4696 T15544 T15542 xcomp addressed,have
R4697 T15545 T15544 auxpass be,addressed
R4698 T15546 T15544 advcl using,addressed
R4699 T15547 T15548 det a,strategy
R4700 T15548 T15546 dobj strategy,using
R4701 T15549 T15548 amod conditional,strategy
R4702 T15550 T15551 compound gene,targeting
R4703 T15551 T15548 compound targeting,strategy
R4704 T15552 T15525 punct .,remain

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T15402 245-258 GO:0009790 denotes embryogenesis
T15401 238-244 NCBITaxon:39107 denotes murine
T15400 137-145 SO:0001060 denotes isoforms
T15409 672-676 SO:0000704 denotes gene
T15408 593-597 NCBITaxon:10088 denotes mice
T15407 587-592 UBERON:0007023 denotes adult
T15406 566-579 GO:0009790 denotes embryogenesis
T15405 553-565 GO:0007566 denotes implantation
T15404 463-471 SO:0001060 denotes isoforms
T15403 284-296 GO:0007566 denotes implantation

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T15429 672-676 SO_EXT:0000704 denotes gene
T15428 593-597 NCBITaxon:10088 denotes mice
T15427 587-592 UBERON:0007023 denotes adult
T15426 566-579 GO:0009790 denotes embryogenesis
T15425 553-565 GO:0007566 denotes implantation
T15424 531-540 GO_PR_EXT:calpain_2_complex denotes m-calpain
T15423 463-471 SO_EXT:0001060 denotes isoforms
T15422 425-434 GO_PR_EXT:calpain_2_complex denotes m-calpain
T15421 427-434 GO_PR_EXT:calpain_1_complex denotes calpain
T15420 418-420 _FRAGMENT denotes μ-
T15419 362-371 GO_PR_EXT:calpain_1_complex denotes μ-calpain
T15418 284-296 GO:0007566 denotes implantation
T15417 245-258 GO:0009790 denotes embryogenesis
T15416 238-244 NCBITaxon:39107 denotes murine
T15415 197-206 GO_PR_EXT:calpain_2_complex denotes m-calpain
T15414 154-163 GO_PR_EXT:calpain_2_complex denotes m-calpain
T15413 156-163 GO_PR_EXT:calpain_1_complex denotes calpain
T15412 147-149 _FRAGMENT denotes μ-
T15411 137-145 SO_EXT:0001060 denotes isoforms
T15410 87-100 GO_PATO_EXT:physiological_process_or_quality denotes physiological
R4587 T15413 T15412 _lexicallyChainedTo calpain,μ-
R4588 T15421 T15420 _lexicallyChainedTo calpain,μ-