
PMC:1382200 / 27386-27964
Annnotations
craft-sa-dev
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T15017 | 577-578 | . | denotes | . |
T15016 | 569-577 | NNS | denotes | attempts |
T15015 | 563-568 | DT | denotes | these |
T15014 | 550-553 | RB | denotes | far |
T15013 | 545-549 | RB | denotes | thus |
T15012 | 541-544 | VBZ | denotes | has |
T15011 | 524-530 | NN | denotes | rescue |
T15010 | 531-540 | NN | denotes | transgene |
T15009 | 520-523 | DT | denotes | the |
T15008 | 517-519 | IN | denotes | of |
T15007 | 506-516 | NN | denotes | expression |
T15006 | 499-505 | JJ | denotes | stable |
T15005 | 489-498 | VBG | denotes | achieving |
T15004 | 486-488 | IN | denotes | in |
T15003 | 475-485 | NN | denotes | difficulty |
T15002 | 473-475 | , | denotes | , |
T15001 | 554-562 | VBN | denotes | hampered |
T15000 | 466-473 | RB | denotes | However |
T14999 | 465-578 | sentence | denotes | However, difficulty in achieving stable expression of the rescue transgene has thus far hampered these attempts. |
T14998 | 464-465 | . | denotes | . |
T14997 | 457-459 | VBZ | denotes | is |
T14996 | 444-445 | HYPH | denotes | - |
T14995 | 445-449 | NN | denotes | type |
T14994 | 440-444 | JJ | denotes | wild |
T14993 | 429-439 | JJ | denotes | endogenous |
T14992 | 419-428 | VBG | denotes | remaining |
T14991 | 450-456 | NN | denotes | allele |
T14990 | 415-418 | DT | denotes | the |
T14989 | 460-464 | VBN | denotes | lost |
T14988 | 408-414 | IN | denotes | before |
T14987 | 399-407 | NN | denotes | activity |
T14986 | 390-391 | HYPH | denotes | - |
T14985 | 391-398 | NN | denotes | calpain |
T14984 | 389-390 | NN | denotes | m |
T14983 | 369-381 | RB | denotes | preemptively |
T14982 | 382-388 | VB | denotes | rescue |
T14981 | 366-368 | TO | denotes | to |
T14980 | 360-365 | NN | denotes | order |
T14979 | 357-359 | IN | denotes | in |
T14978 | 346-356 | NN | denotes | conversion |
T14977 | 341-345 | NN | denotes | gene |
T14976 | 338-340 | IN | denotes | to |
T14975 | 332-337 | JJ | denotes | prior |
T14974 | 315-321 | NN | denotes | rescue |
T14973 | 310-314 | NN | denotes | cDNA |
T14972 | 304-309 | NN | denotes | Capn2 |
T14971 | 322-331 | NN | denotes | transgene |
T14970 | 302-303 | DT | denotes | a |
T14969 | 297-301 | IN | denotes | from |
T14968 | 287-288 | NN | denotes | k |
T14967 | 284-286 | CD | denotes | 80 |
T14966 | 283-284 | HYPH | denotes | - |
T14965 | 282-283 | NN | denotes | m |
T14964 | 289-296 | NN | denotes | subunit |
T14963 | 278-281 | DT | denotes | the |
T14962 | 270-277 | VB | denotes | express |
T14961 | 267-269 | TO | denotes | to |
T14960 | 263-266 | RB | denotes | way |
T14959 | 257-262 | RB | denotes | under |
T14958 | 253-256 | VBP | denotes | are |
T14957 | 245-252 | NNS | denotes | Efforts |
T14956 | 244-465 | sentence | denotes | Efforts are under way to express the m-80 k subunit from a Capn2 cDNA rescue transgene prior to gene conversion in order to preemptively rescue m-calpain activity before the remaining endogenous wild-type allele is lost. |
T14955 | 243-244 | . | denotes | . |
T14954 | 238-243 | NNS | denotes | cells |
T14953 | 235-237 | NN | denotes | ES |
T14952 | 232-234 | IN | denotes | of |
T14951 | 222-231 | NN | denotes | selection |
T14950 | 215-221 | JJ | denotes | clonal |
T14949 | 212-214 | CC | denotes | or |
T14948 | 202-211 | NN | denotes | viability |
T14947 | 197-201 | NN | denotes | cell |
T14946 | 177-184 | RB | denotes | somehow |
T14945 | 164-170 | NN | denotes | mutant |
T14944 | 153-163 | JJ | denotes | homozygous |
T14943 | 171-176 | NN | denotes | state |
T14942 | 149-152 | DT | denotes | the |
T14941 | 185-196 | VBZ | denotes | compromises |
T14940 | 144-148 | IN | denotes | that |
T14939 | 130-134 | NN | denotes | G418 |
T14938 | 127-129 | IN | denotes | of |
T14937 | 112-126 | NNS | denotes | concentrations |
T14936 | 107-111 | JJ | denotes | high |
T14935 | 104-106 | IN | denotes | in |
T14934 | 97-103 | NNS | denotes | clones |
T14933 | 94-96 | IN | denotes | of |
T14932 | 84-93 | NN | denotes | selection |
T14931 | 81-83 | IN | denotes | by |
T14930 | 75-80 | NNS | denotes | cells |
T14929 | 72-74 | NN | denotes | ES |
T14928 | 70-71 | SYM | denotes | - |
T14927 | 69-70 | HYPH | denotes | / |
T14926 | 68-69 | SYM | denotes | - |
T14925 | 63-68 | NN | denotes | Capn2 |
T14924 | 60-62 | IN | denotes | to |
T14923 | 58-59 | SYM | denotes | - |
T14922 | 57-58 | HYPH | denotes | / |
T14921 | 56-57 | SYM | denotes | + |
T14920 | 51-56 | NN | denotes | Capn2 |
T14919 | 48-50 | IN | denotes | of |
T14918 | 37-47 | NN | denotes | conversion |
T14917 | 32-36 | NN | denotes | gene |
T14916 | 24-31 | VB | denotes | achieve |
T14915 | 21-23 | TO | denotes | to |
T14914 | 135-143 | VBZ | denotes | suggests |
T14913 | 4-12 | VBN | denotes | repeated |
T14912 | 13-20 | NN | denotes | failure |
T14911 | 0-3 | DT | denotes | The |
R4274 | T14911 | T14912 | det | The,failure |
R4275 | T14912 | T14914 | nsubj | failure,suggests |
R4277 | T14913 | T14912 | amod | repeated,failure |
R4278 | T14915 | T14916 | aux | to,achieve |
R4279 | T14916 | T14912 | acl | achieve,failure |
R4280 | T14917 | T14918 | compound | gene,conversion |
R4282 | T14918 | T14916 | dobj | conversion,achieve |
R4283 | T14919 | T14918 | prep | of,conversion |
R4284 | T14920 | T14919 | pobj | Capn2,of |
R4286 | T14921 | T14920 | punct | +,Capn2 |
R4287 | T14922 | T14920 | punct | /,Capn2 |
R4288 | T14923 | T14920 | punct | -,Capn2 |
R4290 | T14924 | T14918 | prep | to,conversion |
R4291 | T14925 | T14924 | pobj | Capn2,to |
R4293 | T14926 | T14925 | punct | -,Capn2 |
R4294 | T14927 | T14925 | punct | /,Capn2 |
R4295 | T14928 | T14925 | punct | -,Capn2 |
R4297 | T14929 | T14930 | compound | ES,cells |
R4298 | T14930 | T14918 | appos | cells,conversion |
R4300 | T14931 | T14918 | prep | by,conversion |
R4301 | T14932 | T14931 | pobj | selection,by |
R4302 | T14933 | T14932 | prep | of,selection |
R4304 | T14934 | T14933 | pobj | clones,of |
R4305 | T14935 | T14932 | prep | in,selection |
R4307 | T14936 | T14937 | amod | high,concentrations |
R4308 | T14937 | T14935 | pobj | concentrations,in |
R4309 | T14938 | T14937 | prep | of,concentrations |
R4311 | T14939 | T14938 | pobj | G418,of |
R4312 | T14940 | T14941 | mark | that,compromises |
R4314 | T14941 | T14914 | ccomp | compromises,suggests |
R4315 | T14942 | T14943 | det | the,state |
R4316 | T14943 | T14941 | nsubj | state,compromises |
R4318 | T14944 | T14943 | amod | homozygous,state |
R4319 | T14945 | T14943 | compound | mutant,state |
R4320 | T14946 | T14941 | advmod | somehow,compromises |
R4322 | T14947 | T14948 | compound | cell,viability |
R4323 | T14948 | T14941 | dobj | viability,compromises |
R4325 | T14949 | T14948 | cc | or,viability |
R4326 | T14950 | T14951 | amod | clonal,selection |
R4327 | T14951 | T14948 | conj | selection,viability |
R4329 | T14952 | T14951 | prep | of,selection |
R4330 | T14953 | T14954 | compound | ES,cells |
R4331 | T14954 | T14952 | pobj | cells,of |
R4332 | T14955 | T14914 | punct | .,suggests |
R4334 | T14957 | T14958 | nsubj | Efforts,are |
R4335 | T14959 | T14960 | advmod | under,way |
R4337 | T14960 | T14958 | advmod | way,are |
R4338 | T14961 | T14962 | aux | to,express |
R4340 | T14962 | T14958 | xcomp | express,are |
R4341 | T14963 | T14964 | det | the,subunit |
R4344 | T14964 | T14962 | dobj | subunit,express |
R4345 | T14965 | T14964 | nmod | m,subunit |
R4346 | T14966 | T14965 | punct | -,m |
R4348 | T14967 | T14965 | nummod | 80,m |
R4349 | T14968 | T14964 | compound | k,subunit |
R4350 | T14969 | T14964 | prep | from,subunit |
R4352 | T14970 | T14971 | det | a,transgene |
R4353 | T14971 | T14969 | pobj | transgene,from |
R4355 | T14972 | T14971 | compound | Capn2,transgene |
R4356 | T14973 | T14971 | compound | cDNA,transgene |
R4358 | T14974 | T14971 | compound | rescue,transgene |
R4359 | T14975 | T14976 | amod | prior,to |
R4360 | T14976 | T14962 | prep | to,express |
R4362 | T14977 | T14978 | compound | gene,conversion |
R4363 | T14978 | T14976 | pobj | conversion,to |
R4364 | T14979 | T14962 | prep | in,express |
R4366 | T14980 | T14979 | pobj | order,in |
R4367 | T14981 | T14982 | aux | to,rescue |
R4369 | T14982 | T14980 | acl | rescue,order |
R4370 | T14983 | T14982 | advmod | preemptively,rescue |
R4371 | T14984 | T14985 | compound | m,calpain |
R4373 | T14985 | T14987 | compound | calpain,activity |
R4374 | T14986 | T14985 | punct | -,calpain |
R4375 | T14987 | T14982 | dobj | activity,rescue |
R4377 | T14988 | T14989 | mark | before,lost |
R4378 | T14989 | T14982 | advcl | lost,rescue |
R4379 | T14990 | T14991 | det | the,allele |
R4381 | T14991 | T14989 | nsubjpass | allele,lost |
R4382 | T14992 | T14991 | amod | remaining,allele |
R4383 | T14993 | T14991 | amod | endogenous,allele |
R4386 | T14994 | T14995 | amod | wild,type |
R4387 | T14995 | T14991 | compound | type,allele |
R4388 | T14996 | T14995 | punct | -,type |
R4390 | T14997 | T14989 | auxpass | is,lost |
R4391 | T14998 | T14958 | punct | .,are |
R4393 | T15000 | T15001 | advmod | However,hampered |
R4395 | T15002 | T15001 | punct | ", ",hampered |
R4396 | T15003 | T15001 | nsubj | difficulty,hampered |
R4398 | T15004 | T15003 | prep | in,difficulty |
R4399 | T15005 | T15004 | pcomp | achieving,in |
R4400 | T15006 | T15007 | amod | stable,expression |
R4402 | T15007 | T15005 | dobj | expression,achieving |
R4403 | T15008 | T15007 | prep | of,expression |
R4404 | T15009 | T15010 | det | the,transgene |
R4406 | T15010 | T15008 | pobj | transgene,of |
R4407 | T15011 | T15010 | compound | rescue,transgene |
R4409 | T15012 | T15001 | aux | has,hampered |
R4410 | T15013 | T15014 | advmod | thus,far |
R4411 | T15014 | T15001 | advmod | far,hampered |
R4413 | T15015 | T15016 | det | these,attempts |
R4414 | T15016 | T15001 | dobj | attempts,hampered |
R4416 | T15017 | T15001 | punct | .,hampered |
craft-ca-core-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T12390 | 72-80 | CL:0002322 | denotes | ES cells |
T12389 | 63-68 | PR:000005015 | denotes | Capn2 |
T12388 | 51-56 | PR:000005015 | denotes | Capn2 |
T12387 | 32-47 | GO:0035822 | denotes | gene conversion |
T12386 | 32-36 | SO:0000704 | denotes | gene |
T12396 | 322-331 | SO:0000902 | denotes | transgene |
T12395 | 304-309 | PR:000005015 | denotes | Capn2 |
T12394 | 282-296 | PR:000005015 | denotes | m-80 k subunit |
T12393 | 270-277 | GO:0010467 | denotes | express |
T12392 | 235-243 | CL:0002322 | denotes | ES cells |
T12391 | 130-134 | CHEBI:42768 | denotes | G418 |
T12401 | 531-540 | SO:0000902 | denotes | transgene |
T12400 | 506-516 | GO:0010467 | denotes | expression |
T12399 | 450-456 | SO:0001023 | denotes | allele |
T12398 | 341-356 | GO:0035822 | denotes | gene conversion |
T12397 | 341-345 | SO:0000704 | denotes | gene |
craft-ca-core-ex-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T12799 | 531-540 | SO_EXT:0000902 | denotes | transgene |
T12798 | 524-530 | SO_EXT:sequence_rescue_process | denotes | rescue |
T12797 | 506-516 | GO:0010467 | denotes | expression |
T12796 | 450-456 | SO_EXT:0001023 | denotes | allele |
T12795 | 440-449 | SO_EXT:wild_type_entity_or_quality | denotes | wild-type |
T12794 | 389-398 | GO_PR_EXT:calpain_2_complex | denotes | m-calpain |
T12793 | 382-388 | SO_EXT:sequence_rescue_process | denotes | rescue |
T12792 | 341-356 | GO:0035822 | denotes | gene conversion |
T12791 | 341-345 | SO_EXT:0000704 | denotes | gene |
T12790 | 322-331 | SO_EXT:0000902 | denotes | transgene |
T12789 | 315-321 | SO_EXT:sequence_rescue_process | denotes | rescue |
T12788 | 310-314 | SO_EXT:cDNA | denotes | cDNA |
T12787 | 304-309 | PR_EXT:000005015 | denotes | Capn2 |
T12786 | 282-296 | PR_EXT:000005015 | denotes | m-80 k subunit |
T12785 | 270-277 | GO:0010467 | denotes | express |
T12784 | 238-243 | CL_GO_EXT:cell | denotes | cells |
T12783 | 235-243 | CL:0002322 | denotes | ES cells |
T12782 | 215-221 | SO_EXT:sequence_cloned_entity | denotes | clonal |
T12781 | 197-201 | CL_GO_EXT:cell | denotes | cell |
T12780 | 164-170 | SO_EXT:sequence_altered_entity_or_alteration_process | denotes | mutant |
T12779 | 130-134 | CHEBI:42768 | denotes | G418 |
T12778 | 97-103 | SO_EXT:sequence_cloned_entity | denotes | clones |
T12777 | 75-80 | CL_GO_EXT:cell | denotes | cells |
T12776 | 72-80 | CL:0002322 | denotes | ES cells |
T12775 | 70-71 | SO_EXT:sequence_nullness_or_absence | denotes | - |
T12774 | 68-69 | SO_EXT:sequence_nullness_or_absence | denotes | - |
T12773 | 63-68 | PR_EXT:000005015 | denotes | Capn2 |
T12772 | 58-59 | SO_EXT:sequence_nullness_or_absence | denotes | - |
T12771 | 56-57 | SO_EXT:normal_or_wild_type_or_present | denotes | + |
T12770 | 51-56 | PR_EXT:000005015 | denotes | Capn2 |
T12769 | 32-47 | GO:0035822 | denotes | gene conversion |
T12768 | 32-36 | SO_EXT:0000704 | denotes | gene |