Id |
Subject |
Object |
Predicate |
Lexical cue |
T14439 |
1266-1267 |
. |
denotes |
. |
T14438 |
1252-1256 |
NN |
denotes |
cell |
T14437 |
1257-1266 |
NNS |
denotes |
divisions |
T14436 |
1249-1250 |
SYM |
denotes |
– |
T14435 |
1250-1251 |
CD |
denotes |
3 |
T14434 |
1248-1249 |
CD |
denotes |
2 |
T14433 |
1240-1247 |
IN |
denotes |
through |
T14432 |
1232-1239 |
NN |
denotes |
protein |
T14431 |
1229-1231 |
CC |
denotes |
or |
T14430 |
1228-1229 |
HYPH |
denotes |
/ |
T14429 |
1225-1228 |
CC |
denotes |
and |
T14428 |
1220-1224 |
NN |
denotes |
mRNA |
T14427 |
1211-1212 |
HYPH |
denotes |
- |
T14426 |
1210-1211 |
NN |
denotes |
m |
T14425 |
1201-1209 |
JJ |
denotes |
maternal |
T14424 |
1212-1219 |
NN |
denotes |
calpain |
T14423 |
1196-1200 |
DT |
denotes |
some |
T14422 |
1193-1195 |
IN |
denotes |
of |
T14421 |
1181-1192 |
NN |
denotes |
persistence |
T14420 |
1177-1180 |
DT |
denotes |
the |
T14419 |
1174-1176 |
IN |
denotes |
to |
T14418 |
1170-1173 |
IN |
denotes |
due |
T14417 |
1163-1169 |
RB |
denotes |
likely |
T14416 |
1158-1162 |
RBS |
denotes |
most |
T14415 |
1143-1144 |
HYPH |
denotes |
- |
T14414 |
1144-1148 |
NN |
denotes |
cell |
T14413 |
1142-1143 |
CD |
denotes |
8 |
T14412 |
1149-1154 |
NN |
denotes |
stage |
T14411 |
1138-1141 |
DT |
denotes |
the |
T14410 |
1135-1137 |
IN |
denotes |
to |
T14409 |
1125-1126 |
SYM |
denotes |
- |
T14408 |
1124-1125 |
HYPH |
denotes |
/ |
T14407 |
1123-1124 |
SYM |
denotes |
- |
T14406 |
1118-1123 |
NN |
denotes |
Capn2 |
T14405 |
1114-1117 |
JJ |
denotes |
few |
T14404 |
1127-1134 |
NNS |
denotes |
embryos |
T14403 |
1112-1113 |
DT |
denotes |
a |
T14402 |
1109-1111 |
IN |
denotes |
of |
T14401 |
1100-1108 |
NN |
denotes |
survival |
T14400 |
1096-1099 |
DT |
denotes |
the |
T14399 |
1094-1096 |
, |
denotes |
, |
T14398 |
1085-1094 |
NN |
denotes |
viability |
T14397 |
1080-1084 |
NN |
denotes |
cell |
T14396 |
1077-1079 |
IN |
denotes |
of |
T14395 |
1070-1076 |
NN |
denotes |
aspect |
T14394 |
1065-1069 |
DT |
denotes |
some |
T14376 |
993-997 |
IN |
denotes |
into |
T14375 |
988-992 |
VBZ |
denotes |
fits |
T14374 |
973-978 |
NN |
denotes |
Capn2 |
T14373 |
979-987 |
NN |
denotes |
knockout |
T14372 |
969-972 |
DT |
denotes |
The |
T14371 |
968-1018 |
sentence |
denotes |
The Capn2 knockout fits into the latter category. |
T14370 |
967-968 |
. |
denotes |
. |
T14369 |
956-958 |
VB |
denotes |
be |
T14368 |
952-955 |
RB |
denotes |
not |
T14367 |
946-951 |
MD |
denotes |
could |
T14366 |
959-967 |
VBN |
denotes |
isolated |
T14365 |
937-939 |
NN |
denotes |
ES |
T14364 |
930-936 |
NN |
denotes |
mutant |
T14363 |
940-945 |
NNS |
denotes |
cells |
T14362 |
919-929 |
JJ |
denotes |
homozygous |
T14361 |
915-918 |
CC |
denotes |
and |
T14360 |
901-905 |
RB |
denotes |
ever |
T14359 |
897-900 |
VBP |
denotes |
are |
T14358 |
884-888 |
JJ |
denotes |
null |
T14357 |
880-883 |
JJ |
denotes |
few |
T14356 |
878-879 |
DT |
denotes |
a |
T14355 |
889-896 |
NNS |
denotes |
embryos |
T14354 |
873-877 |
RB |
denotes |
only |
T14353 |
871-873 |
, |
denotes |
, |
T14352 |
862-871 |
NNS |
denotes |
instances |
T14351 |
856-861 |
DT |
denotes |
these |
T14350 |
906-914 |
VBN |
denotes |
observed |
T14349 |
853-855 |
IN |
denotes |
In |
T14348 |
852-968 |
sentence |
denotes |
In these instances, only a few null embryos are ever observed and homozygous mutant ES cells could not be isolated. |
T14347 |
851-852 |
. |
denotes |
. |
T14346 |
850-851 |
-RRB- |
denotes |
] |
T14345 |
848-850 |
CD |
denotes |
43 |
T14344 |
847-848 |
SYM |
denotes |
- |
T14343 |
844-845 |
, |
denotes |
, |
T14342 |
843-844 |
CD |
denotes |
3 |
T14341 |
845-847 |
CD |
denotes |
39 |
T14340 |
842-843 |
-LRB- |
denotes |
[ |
T14339 |
829-834 |
JJ |
denotes |
early |
T14338 |
835-841 |
NN |
denotes |
embryo |
T14337 |
825-828 |
DT |
denotes |
the |
T14336 |
822-824 |
IN |
denotes |
in |
T14335 |
816-821 |
NNS |
denotes |
cells |
T14334 |
813-815 |
IN |
denotes |
of |
T14333 |
803-812 |
NN |
denotes |
viability |
T14332 |
799-802 |
DT |
denotes |
the |
T14331 |
791-798 |
RB |
denotes |
fatally |
T14330 |
780-790 |
VB |
denotes |
compromise |
T14329 |
777-779 |
TO |
denotes |
to |
T14328 |
766-768 |
VBZ |
denotes |
is |
T14327 |
750-754 |
NN |
denotes |
gene |
T14326 |
755-765 |
NN |
denotes |
disruption |
T14325 |
746-749 |
DT |
denotes |
the |
T14324 |
744-746 |
, |
denotes |
, |
T14323 |
737-744 |
RB |
denotes |
however |
T14322 |
735-737 |
, |
denotes |
, |
T14321 |
730-735 |
NNS |
denotes |
cases |
T14320 |
724-729 |
JJ |
denotes |
other |
T14319 |
769-776 |
VBN |
denotes |
thought |
T14318 |
721-723 |
IN |
denotes |
In |
T14317 |
720-852 |
sentence |
denotes |
In other cases, however, the gene disruption is thought to compromise fatally the viability of cells in the early embryo [3,39-43]. |
T14316 |
719-720 |
. |
denotes |
. |
T14315 |
706-713 |
RB |
denotes |
usually |
T14314 |
703-705 |
VBZ |
denotes |
is |
T14313 |
693-702 |
NNS |
denotes |
genotypes |
T14312 |
683-692 |
JJ |
denotes |
embryonic |
T14311 |
680-682 |
IN |
denotes |
of |
T14310 |
714-719 |
VBN |
denotes |
noted |
T14309 |
657-666 |
JJ |
denotes |
Mendelian |
T14308 |
667-679 |
NN |
denotes |
distribution |
T14307 |
655-656 |
DT |
denotes |
a |
T14306 |
651-654 |
CC |
denotes |
and |
T14305 |
649-651 |
, |
denotes |
, |
T14304 |
637-643 |
NN |
denotes |
morula |
T14303 |
644-649 |
NN |
denotes |
stage |
T14302 |
633-636 |
DT |
denotes |
the |
T14301 |
626-632 |
IN |
denotes |
beyond |
T14300 |
612-617 |
RB |
denotes |
often |
T14299 |
607-611 |
NN |
denotes |
type |
T14298 |
602-606 |
DT |
denotes |
this |
T14297 |
599-601 |
IN |
denotes |
of |
T14296 |
618-625 |
VBP |
denotes |
survive |
T14295 |
591-598 |
NNS |
denotes |
embryos |
T14294 |
586-590 |
JJ |
denotes |
Null |
T14293 |
585-720 |
sentence |
denotes |
Null embryos of this type often survive beyond the morula stage, and a Mendelian distribution of embryonic genotypes is usually noted. |
T14292 |
584-585 |
. |
denotes |
. |
T14291 |
583-584 |
-RRB- |
denotes |
] |
T14290 |
581-583 |
CD |
denotes |
38 |
T14289 |
580-581 |
-LRB- |
denotes |
[ |
T14288 |
564-579 |
RB |
denotes |
morphologically |
T14287 |
552-554 |
VB |
denotes |
be |
T14286 |
546-551 |
RB |
denotes |
often |
T14285 |
542-545 |
MD |
denotes |
can |
T14284 |
555-563 |
VBN |
denotes |
observed |
T14283 |
536-541 |
WDT |
denotes |
which |
T14282 |
512-527 |
NN |
denotes |
differentiation |
T14281 |
502-511 |
JJ |
denotes |
embryonic |
T14280 |
528-535 |
NN |
denotes |
program |
T14279 |
498-501 |
DT |
denotes |
the |
T14278 |
495-497 |
IN |
denotes |
in |
T14277 |
482-485 |
VBP |
denotes |
are |
T14276 |
474-481 |
NNS |
denotes |
defects |
T14275 |
472-474 |
, |
denotes |
, |
T14274 |
467-472 |
NNS |
denotes |
cases |
T14273 |
462-466 |
DT |
denotes |
some |
T14272 |
486-494 |
VBN |
denotes |
incurred |
T14271 |
459-461 |
IN |
denotes |
In |
T14270 |
458-585 |
sentence |
denotes |
In some cases, defects are incurred in the embryonic differentiation program which can often be observed morphologically [38]. |
T14269 |
457-458 |
. |
denotes |
. |
T14268 |
443-450 |
JJ |
denotes |
general |
T14267 |
451-457 |
NNS |
denotes |
causes |
T14266 |
439-442 |
CD |
denotes |
two |
T14265 |
436-438 |
IN |
denotes |
to |
T14264 |
422-424 |
VB |
denotes |
be |
T14263 |
412-421 |
RB |
denotes |
typically |
T14262 |
408-411 |
MD |
denotes |
can |
T14261 |
398-407 |
NNS |
denotes |
knockouts |
T14260 |
393-397 |
NN |
denotes |
gene |
T14259 |
388-392 |
IN |
denotes |
from |
T14258 |
378-387 |
VBG |
denotes |
resulting |
T14257 |
425-435 |
VBN |
denotes |
attributed |
T14256 |
368-377 |
NN |
denotes |
lethality |
T14255 |
352-367 |
NN |
denotes |
Preimplantation |
T14254 |
351-458 |
sentence |
denotes |
Preimplantation lethality resulting from gene knockouts can typically be attributed to two general causes. |
T14253 |
350-351 |
. |
denotes |
. |
T14252 |
341-350 |
VBG |
denotes |
revealing |
T14251 |
334-340 |
PRP |
denotes |
itself |
T14250 |
331-333 |
IN |
denotes |
in |
T14249 |
326-327 |
SYM |
denotes |
- |
T14248 |
325-326 |
HYPH |
denotes |
/ |
T14247 |
324-325 |
SYM |
denotes |
- |
T14246 |
319-324 |
NN |
denotes |
Capn2 |
T14245 |
316-318 |
VB |
denotes |
be |
T14244 |
313-315 |
TO |
denotes |
to |
T14243 |
281-297 |
JJ |
denotes |
pre-implantation |
T14242 |
271-280 |
VBN |
denotes |
genotyped |
T14241 |
258-270 |
RB |
denotes |
successfully |
T14240 |
252-254 |
IN |
denotes |
of |
T14239 |
248-251 |
IN |
denotes |
out |
T14238 |
255-257 |
CD |
denotes |
90 |
T14237 |
244-247 |
CD |
denotes |
two |
T14236 |
298-305 |
NNS |
denotes |
embryos |
T14235 |
239-243 |
RB |
denotes |
only |
T14234 |
306-312 |
VBD |
denotes |
proved |
T14233 |
234-238 |
IN |
denotes |
that |
T14232 |
229-233 |
NN |
denotes |
fact |
T14231 |
225-228 |
DT |
denotes |
the |
T14230 |
223-225 |
, |
denotes |
, |
T14229 |
328-330 |
VBZ |
denotes |
is |
T14228 |
216-223 |
RB |
denotes |
However |
T14227 |
215-351 |
sentence |
denotes |
However, the fact that only two out of 90 successfully genotyped pre-implantation embryos proved to be Capn2-/- is in itself revealing. |
T14226 |
214-215 |
. |
denotes |
. |
T14225 |
193-206 |
JJ |
denotes |
morphological |
T14224 |
185-192 |
JJ |
denotes |
obvious |
T14223 |
207-214 |
NNS |
denotes |
defects |
T14222 |
181-184 |
DT |
denotes |
any |
T14221 |
169-172 |
RB |
denotes |
not |
T14220 |
165-168 |
VBD |
denotes |
did |
T14219 |
153-154 |
HYPH |
denotes |
- |
T14218 |
154-158 |
NN |
denotes |
cell |
T14217 |
152-153 |
CD |
denotes |
8 |
T14216 |
159-164 |
NN |
denotes |
stage |
T14215 |
148-151 |
DT |
denotes |
the |
T14214 |
145-147 |
IN |
denotes |
at |
T14213 |
134-144 |
VBN |
denotes |
identified |
T14212 |
173-180 |
VB |
denotes |
present |
T14211 |
121-125 |
JJ |
denotes |
null |
T14210 |
110-120 |
JJ |
denotes |
homozygous |
T14209 |
106-109 |
CD |
denotes |
two |
T14208 |
126-133 |
NNS |
denotes |
embryos |
T14207 |
102-105 |
DT |
denotes |
The |
T14206 |
101-215 |
sentence |
denotes |
The two homozygous null embryos identified at the 8-cell stage did not present any obvious morphological defects. |
T14205 |
100-101 |
. |
denotes |
. |
T14204 |
86-90 |
VBN |
denotes |
been |
T14203 |
82-85 |
RB |
denotes |
yet |
T14202 |
78-81 |
RB |
denotes |
not |
T14201 |
74-77 |
VBZ |
denotes |
has |
T14200 |
64-65 |
SYM |
denotes |
- |
T14199 |
63-64 |
HYPH |
denotes |
/ |
T14198 |
62-63 |
SYM |
denotes |
- |
T14197 |
66-73 |
NNS |
denotes |
embryos |
T14196 |
57-62 |
NN |
denotes |
Capn2 |
T14195 |
54-56 |
IN |
denotes |
in |
T14194 |
28-43 |
NN |
denotes |
preimplantation |
T14193 |
44-53 |
NN |
denotes |
lethality |
T14192 |
24-27 |
DT |
denotes |
the |
T14191 |
21-23 |
IN |
denotes |
of |
T14190 |
91-100 |
VBN |
denotes |
clarified |
T14189 |
4-14 |
VBG |
denotes |
underlying |
T14188 |
15-20 |
NN |
denotes |
cause |
T14187 |
0-3 |
DT |
denotes |
The |
T14393 |
1061-1064 |
IN |
denotes |
for |
T14392 |
1051-1060 |
JJ |
denotes |
essential |
T14391 |
1039-1040 |
HYPH |
denotes |
- |
T14390 |
1040-1047 |
NN |
denotes |
calpain |
T14389 |
1038-1039 |
NN |
denotes |
m |
T14388 |
1048-1050 |
VBZ |
denotes |
is |
T14387 |
1033-1037 |
IN |
denotes |
that |
T14386 |
1028-1032 |
JJ |
denotes |
true |
T14385 |
1155-1157 |
VBZ |
denotes |
is |
T14384 |
1022-1024 |
PRP |
denotes |
it |
T14383 |
1025-1027 |
VBZ |
denotes |
is |
T14382 |
1019-1021 |
IN |
denotes |
If |
T14381 |
1018-1267 |
sentence |
denotes |
If it is true that m-calpain is essential for some aspect of cell viability, the survival of a few Capn2-/- embryos to the 8-cell stage is most likely due to the persistence of some maternal m-calpain mRNA and/or protein through 2–3 cell divisions. |
T14380 |
1017-1018 |
. |
denotes |
. |
T14379 |
1002-1008 |
JJ |
denotes |
latter |
T14378 |
1009-1017 |
NN |
denotes |
category |
T14377 |
998-1001 |
DT |
denotes |
the |
R3606 |
T14187 |
T14188 |
det |
The,cause |
R3608 |
T14188 |
T14190 |
nsubjpass |
cause,clarified |
R3609 |
T14189 |
T14188 |
amod |
underlying,cause |
R3611 |
T14191 |
T14188 |
prep |
of,cause |
R3612 |
T14192 |
T14193 |
det |
the,lethality |
R3613 |
T14193 |
T14191 |
pobj |
lethality,of |
R3615 |
T14194 |
T14193 |
compound |
preimplantation,lethality |
R3616 |
T14195 |
T14188 |
prep |
in,cause |
R3617 |
T14196 |
T14197 |
nmod |
Capn2,embryos |
R3619 |
T14197 |
T14195 |
pobj |
embryos,in |
R3620 |
T14198 |
T14196 |
punct |
-,Capn2 |
R3622 |
T14199 |
T14196 |
punct |
/,Capn2 |
R3623 |
T14200 |
T14196 |
punct |
-,Capn2 |
R3624 |
T14201 |
T14190 |
aux |
has,clarified |
R3626 |
T14202 |
T14190 |
neg |
not,clarified |
R3627 |
T14203 |
T14190 |
advmod |
yet,clarified |
R3628 |
T14204 |
T14190 |
auxpass |
been,clarified |
R3630 |
T14205 |
T14190 |
punct |
.,clarified |
R3632 |
T14207 |
T14208 |
det |
The,embryos |
R3633 |
T14208 |
T14212 |
nsubj |
embryos,present |
R3634 |
T14209 |
T14208 |
nummod |
two,embryos |
R3636 |
T14210 |
T14211 |
amod |
homozygous,null |
R3637 |
T14211 |
T14208 |
amod |
null,embryos |
R3639 |
T14213 |
T14208 |
acl |
identified,embryos |
R3640 |
T14214 |
T14213 |
prep |
at,identified |
R3641 |
T14215 |
T14216 |
det |
the,stage |
R3643 |
T14216 |
T14214 |
pobj |
stage,at |
R3644 |
T14217 |
T14218 |
nummod |
8,cell |
R3645 |
T14218 |
T14216 |
compound |
cell,stage |
R3647 |
T14219 |
T14218 |
punct |
-,cell |
R3648 |
T14220 |
T14212 |
aux |
did,present |
R3649 |
T14221 |
T14212 |
neg |
not,present |
R3651 |
T14222 |
T14223 |
det |
any,defects |
R3652 |
T14223 |
T14212 |
dobj |
defects,present |
R3654 |
T14224 |
T14223 |
amod |
obvious,defects |
R3655 |
T14225 |
T14223 |
amod |
morphological,defects |
R3656 |
T14226 |
T14212 |
punct |
.,present |
R3657 |
T14228 |
T14229 |
advmod |
However,is |
R3659 |
T14230 |
T14229 |
punct |
", ",is |
R3660 |
T14231 |
T14232 |
det |
the,fact |
R3661 |
T14232 |
T14229 |
nsubj |
fact,is |
R3663 |
T14233 |
T14234 |
mark |
that,proved |
R3664 |
T14234 |
T14232 |
acl |
proved,fact |
R3665 |
T14235 |
T14236 |
advmod |
only,embryos |
R3667 |
T14236 |
T14234 |
nsubj |
embryos,proved |
R3668 |
T14237 |
T14238 |
quantmod |
two,90 |
R3669 |
T14238 |
T14236 |
nummod |
90,embryos |
R3671 |
T14239 |
T14238 |
quantmod |
out,90 |
R3672 |
T14240 |
T14238 |
quantmod |
of,90 |
R3673 |
T14241 |
T14242 |
advmod |
successfully,genotyped |
R3675 |
T14242 |
T14236 |
amod |
genotyped,embryos |
R3676 |
T14243 |
T14236 |
amod |
pre-implantation,embryos |
R3677 |
T14244 |
T14245 |
aux |
to,be |
R3679 |
T14245 |
T14234 |
xcomp |
be,proved |
R3680 |
T14246 |
T14245 |
attr |
Capn2,be |
R3681 |
T14247 |
T14246 |
punct |
-,Capn2 |
R3683 |
T14248 |
T14246 |
punct |
/,Capn2 |
R3684 |
T14249 |
T14246 |
punct |
-,Capn2 |
R3686 |
T14250 |
T14229 |
prep |
in,is |
R3687 |
T14251 |
T14250 |
pobj |
itself,in |
R3688 |
T14252 |
T14229 |
acomp |
revealing,is |
R3692 |
T14253 |
T14229 |
punct |
.,is |
R3694 |
T14255 |
T14256 |
compound |
Preimplantation,lethality |
R3695 |
T14256 |
T14257 |
nsubjpass |
lethality,attributed |
R3697 |
T14258 |
T14256 |
acl |
resulting,lethality |
R3698 |
T14259 |
T14258 |
prep |
from,resulting |
R3700 |
T14260 |
T14261 |
compound |
gene,knockouts |
R3701 |
T14261 |
T14259 |
pobj |
knockouts,from |
R3703 |
T14262 |
T14257 |
aux |
can,attributed |
R3704 |
T14263 |
T14257 |
advmod |
typically,attributed |
R3705 |
T14264 |
T14257 |
auxpass |
be,attributed |
R3706 |
T14265 |
T14257 |
prep |
to,attributed |
R3707 |
T14266 |
T14267 |
nummod |
two,causes |
R3708 |
T14267 |
T14265 |
pobj |
causes,to |
R3710 |
T14268 |
T14267 |
amod |
general,causes |
R3711 |
T14269 |
T14257 |
punct |
.,attributed |
R3713 |
T14271 |
T14272 |
prep |
In,incurred |
R3714 |
T14273 |
T14274 |
det |
some,cases |
R3716 |
T14274 |
T14271 |
pobj |
cases,In |
R3717 |
T14275 |
T14272 |
punct |
", ",incurred |
R3719 |
T14276 |
T14272 |
nsubjpass |
defects,incurred |
R3720 |
T14277 |
T14272 |
auxpass |
are,incurred |
R3721 |
T14278 |
T14272 |
prep |
in,incurred |
R3724 |
T14279 |
T14280 |
det |
the,program |
R3726 |
T14280 |
T14278 |
pobj |
program,in |
R3727 |
T14281 |
T14280 |
amod |
embryonic,program |
R3728 |
T14282 |
T14280 |
compound |
differentiation,program |
R3730 |
T14283 |
T14284 |
dep |
which,observed |
R3731 |
T14284 |
T14280 |
relcl |
observed,program |
R3732 |
T14285 |
T14284 |
aux |
can,observed |
R3734 |
T14286 |
T14284 |
advmod |
often,observed |
R3735 |
T14287 |
T14284 |
auxpass |
be,observed |
R3737 |
T14288 |
T14284 |
advmod |
morphologically,observed |
R3738 |
T14289 |
T14290 |
punct |
[,38 |
R3740 |
T14290 |
T14284 |
parataxis |
38,observed |
R3741 |
T14291 |
T14290 |
punct |
],38 |
R3742 |
T14292 |
T14272 |
punct |
.,incurred |
R3744 |
T14294 |
T14295 |
amod |
Null,embryos |
R3745 |
T14295 |
T14296 |
nsubj |
embryos,survive |
R3747 |
T14297 |
T14295 |
prep |
of,embryos |
R3748 |
T14298 |
T14299 |
det |
this,type |
R3750 |
T14299 |
T14297 |
pobj |
type,of |
R3751 |
T14300 |
T14296 |
advmod |
often,survive |
R3753 |
T14301 |
T14296 |
prep |
beyond,survive |
R3754 |
T14302 |
T14303 |
det |
the,stage |
R3755 |
T14303 |
T14301 |
pobj |
stage,beyond |
R3757 |
T14304 |
T14303 |
compound |
morula,stage |
R3758 |
T14305 |
T14296 |
punct |
", ",survive |
R3759 |
T14306 |
T14296 |
cc |
and,survive |
R3760 |
T14307 |
T14308 |
det |
a,distribution |
R3761 |
T14308 |
T14310 |
nsubjpass |
distribution,noted |
R3763 |
T14309 |
T14308 |
amod |
Mendelian,distribution |
R3764 |
T14310 |
T14296 |
conj |
noted,survive |
R3765 |
T14311 |
T14308 |
prep |
of,distribution |
R3767 |
T14312 |
T14313 |
amod |
embryonic,genotypes |
R3768 |
T14313 |
T14311 |
pobj |
genotypes,of |
R3769 |
T14314 |
T14310 |
auxpass |
is,noted |
R3770 |
T14315 |
T14310 |
advmod |
usually,noted |
R3772 |
T14316 |
T14310 |
punct |
.,noted |
R3773 |
T14318 |
T14319 |
prep |
In,thought |
R3775 |
T14320 |
T14321 |
amod |
other,cases |
R3776 |
T14321 |
T14318 |
pobj |
cases,In |
R3777 |
T14322 |
T14319 |
punct |
", ",thought |
R3779 |
T14323 |
T14319 |
advmod |
however,thought |
R3780 |
T14324 |
T14319 |
punct |
", ",thought |
R3782 |
T14325 |
T14326 |
det |
the,disruption |
R3783 |
T14326 |
T14319 |
nsubjpass |
disruption,thought |
R3784 |
T14327 |
T14326 |
compound |
gene,disruption |
R3786 |
T14328 |
T14319 |
auxpass |
is,thought |
R3787 |
T14329 |
T14330 |
aux |
to,compromise |
R3789 |
T14330 |
T14319 |
xcomp |
compromise,thought |
R3790 |
T14331 |
T14330 |
advmod |
fatally,compromise |
R3791 |
T14332 |
T14333 |
det |
the,viability |
R3792 |
T14359 |
T14350 |
auxpass |
are,observed |
R3793 |
T14333 |
T14330 |
dobj |
viability,compromise |
R3794 |
T14334 |
T14333 |
prep |
of,viability |
R3795 |
T14335 |
T14334 |
pobj |
cells,of |
R3796 |
T14336 |
T14335 |
prep |
in,cells |
R3797 |
T14360 |
T14350 |
advmod |
ever,observed |
R3798 |
T14337 |
T14338 |
det |
the,embryo |
R3799 |
T14338 |
T14336 |
pobj |
embryo,in |
R3800 |
T14339 |
T14338 |
amod |
early,embryo |
R3801 |
T14361 |
T14350 |
cc |
and,observed |
R3802 |
T14340 |
T14341 |
punct |
[,39 |
R3803 |
T14341 |
T14330 |
parataxis |
39,compromise |
R3804 |
T14342 |
T14341 |
dep |
3,39 |
R3805 |
T14362 |
T14363 |
amod |
homozygous,cells |
R3806 |
T14343 |
T14341 |
punct |
",",39 |
R3807 |
T14344 |
T14345 |
punct |
-,43 |
R3808 |
T14345 |
T14341 |
prep |
43,39 |
R3809 |
T14363 |
T14366 |
nsubjpass |
cells,isolated |
R3810 |
T14346 |
T14341 |
punct |
],39 |
R3811 |
T14347 |
T14319 |
punct |
.,thought |
R3812 |
T14349 |
T14350 |
prep |
In,observed |
R3813 |
T14364 |
T14363 |
compound |
mutant,cells |
R3814 |
T14351 |
T14352 |
det |
these,instances |
R3815 |
T14352 |
T14349 |
pobj |
instances,In |
R3816 |
T14353 |
T14350 |
punct |
", ",observed |
R3817 |
T14365 |
T14363 |
compound |
ES,cells |
R3818 |
T14354 |
T14355 |
advmod |
only,embryos |
R3819 |
T14355 |
T14350 |
nsubjpass |
embryos,observed |
R3820 |
T14356 |
T14355 |
det |
a,embryos |
R3821 |
T14366 |
T14350 |
conj |
isolated,observed |
R3822 |
T14357 |
T14355 |
amod |
few,embryos |
R3823 |
T14358 |
T14355 |
amod |
null,embryos |
R3824 |
T14367 |
T14366 |
aux |
could,isolated |
R3825 |
T14368 |
T14366 |
neg |
not,isolated |
R3826 |
T14369 |
T14366 |
auxpass |
be,isolated |
R3827 |
T14370 |
T14366 |
punct |
.,isolated |
R3828 |
T14372 |
T14373 |
det |
The,knockout |
R3830 |
T14373 |
T14375 |
nsubj |
knockout,fits |
R3834 |
T14374 |
T14373 |
compound |
Capn2,knockout |
R3837 |
T14376 |
T14375 |
prep |
into,fits |
R3842 |
T14377 |
T14378 |
det |
the,category |
R3846 |
T14378 |
T14376 |
pobj |
category,into |
R3850 |
T14379 |
T14378 |
amod |
latter,category |
R3853 |
T14380 |
T14375 |
punct |
.,fits |
R3857 |
T14382 |
T14383 |
mark |
If,is |
R3865 |
T14383 |
T14385 |
advcl |
is,is |
R3869 |
T14384 |
T14383 |
nsubj |
it,is |
R3871 |
T14386 |
T14383 |
acomp |
true,is |
R3875 |
T14387 |
T14388 |
mark |
that,is |
R3879 |
T14388 |
T14383 |
ccomp |
is,is |
R3883 |
T14389 |
T14390 |
compound |
m,calpain |
R3886 |
T14390 |
T14388 |
nsubj |
calpain,is |
R3890 |
T14391 |
T14390 |
punct |
-,calpain |
R3894 |
T14392 |
T14388 |
acomp |
essential,is |
R3896 |
T14393 |
T14392 |
prep |
for,essential |
R3900 |
T14394 |
T14395 |
det |
some,aspect |
R3903 |
T14395 |
T14393 |
pobj |
aspect,for |
R3905 |
T14396 |
T14395 |
prep |
of,aspect |
R3908 |
T14397 |
T14398 |
compound |
cell,viability |
R3912 |
T14398 |
T14396 |
pobj |
viability,of |
R3920 |
T14399 |
T14385 |
punct |
", ",is |
R3923 |
T14400 |
T14401 |
det |
the,survival |
R3924 |
T14401 |
T14385 |
nsubj |
survival,is |
R3928 |
T14402 |
T14401 |
prep |
of,survival |
R3931 |
T14403 |
T14404 |
det |
a,embryos |
R3934 |
T14404 |
T14402 |
pobj |
embryos,of |
R3937 |
T14405 |
T14404 |
amod |
few,embryos |
R3941 |
T14406 |
T14404 |
nmod |
Capn2,embryos |
R3944 |
T14407 |
T14406 |
punct |
-,Capn2 |
R3947 |
T14408 |
T14406 |
punct |
/,Capn2 |
R3951 |
T14409 |
T14406 |
punct |
-,Capn2 |
R3954 |
T14410 |
T14401 |
prep |
to,survival |
R3958 |
T14411 |
T14412 |
det |
the,stage |
R3962 |
T14412 |
T14410 |
pobj |
stage,to |
R3967 |
T14413 |
T14414 |
nummod |
8,cell |
R3968 |
T14414 |
T14412 |
compound |
cell,stage |
R3972 |
T14415 |
T14414 |
punct |
-,cell |
R3974 |
T14416 |
T14417 |
advmod |
most,likely |
R3977 |
T14417 |
T14418 |
advmod |
likely,due |
R3981 |
T14418 |
T14385 |
prep |
due,is |
R3985 |
T14419 |
T14418 |
pcomp |
to,due |
R3988 |
T14420 |
T14421 |
det |
the,persistence |
R3992 |
T14421 |
T14418 |
pobj |
persistence,due |
R3996 |
T14422 |
T14421 |
prep |
of,persistence |
R4000 |
T14423 |
T14424 |
det |
some,calpain |
R4004 |
T14424 |
T14422 |
pobj |
calpain,of |
R4008 |
T14425 |
T14424 |
amod |
maternal,calpain |
R4011 |
T14426 |
T14424 |
compound |
m,calpain |
R4014 |
T14427 |
T14424 |
punct |
-,calpain |
R4016 |
T14428 |
T14424 |
appos |
mRNA,calpain |
R4022 |
T14429 |
T14428 |
cc |
and,mRNA |
R4026 |
T14430 |
T14429 |
punct |
/,and |
R4029 |
T14431 |
T14429 |
cc |
or,and |
R4033 |
T14432 |
T14428 |
conj |
protein,mRNA |
R4037 |
T14433 |
T14421 |
prep |
through,persistence |
R4038 |
T14434 |
T14435 |
quantmod |
2,3 |
R4040 |
T14435 |
T14437 |
nummod |
3,divisions |
R4042 |
T14436 |
T14435 |
punct |
–,3 |
R4046 |
T14437 |
T14433 |
pobj |
divisions,through |
R4049 |
T14438 |
T14437 |
compound |
cell,divisions |
R4053 |
T14439 |
T14385 |
punct |
.,is |