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PMC:1382200 / 20852-21433 JSONTXT

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Id Subject Object Predicate Lexical cue
T13742 580-581 . denotes .
T13741 579-580 -RRB- denotes ]
T13740 577-579 CD denotes 36
T13739 576-577 -LRB- denotes [
T13738 570-575 NNS denotes cells
T13737 560-569 JJ denotes mammalian
T13736 557-559 IN denotes in
T13735 554-556 CC denotes or
T13734 549-553 NNP denotes coli
T13733 546-548 NNP denotes E.
T13732 543-545 IN denotes in
T13731 536-542 CC denotes either
T13730 530-535 RB denotes alone
T13729 515-519 VBD denotes were
T13728 500-505 JJ denotes large
T13727 506-514 NNS denotes subunits
T13726 492-499 NN denotes calpain
T13725 520-529 VBN denotes expressed
T13724 487-491 WRB denotes when
T13723 481-486 NNS denotes hands
T13722 477-480 PRP$ denotes our
T13721 474-476 IN denotes in
T13720 461-464 VBD denotes was
T13719 465-473 VBN denotes observed
T13718 444-451 NN denotes calpain
T13717 452-460 NN denotes activity
T13716 441-443 DT denotes no
T13715 437-440 CC denotes and
T13714 435-437 , denotes ,
T13713 424-435 NN denotes possibility
T13712 419-423 DT denotes that
T13711 411-418 VB denotes exclude
T13710 408-410 TO denotes to
T13709 387-390 FW denotes al.
T13708 384-386 FW denotes et
T13707 374-383 NNP denotes Zimmerman
T13706 391-399 NN denotes knockout
T13705 370-373 DT denotes the
T13704 400-407 VBZ denotes appears
T13703 361-369 IN denotes although
T13702 359-361 , denotes ,
T13701 354-359 NNS denotes cells
T13700 343-353 JJ denotes eukaryotic
T13699 340-342 IN denotes in
T13698 331-339 NN denotes activity
T13697 326-330 DT denotes some
T13696 312-317 MD denotes might
T13695 306-311 RB denotes alone
T13694 291-296 JJ denotes large
T13693 297-305 NNS denotes subunits
T13692 283-290 NN denotes calpain
T13691 318-325 VB denotes provide
T13690 278-282 IN denotes that
T13689 263-267 VBN denotes been
T13688 258-262 RB denotes also
T13687 254-257 VBZ denotes has
T13686 251-253 PRP denotes It
T13685 249-250 -RRB- denotes )
T13684 245-249 NN denotes work
T13683 233-244 JJ denotes unpublished
T13682 231-233 , denotes ,
T13681 227-231 NNP denotes Elce
T13680 222-226 NNP denotes J.S.
T13679 221-222 -LRB- denotes (
T13678 207-209 VB denotes be
T13677 210-220 VBN denotes determined
T13676 204-206 TO denotes to
T13675 200-203 RB denotes yet
T13674 190-195 NNS denotes cells
T13673 180-189 JJ denotes mammalian
T13672 177-179 IN denotes in
T13671 163-176 NN denotes functionality
T13670 157-162 PRP$ denotes their
T13669 196-199 VBZ denotes has
T13668 148-156 IN denotes although
T13667 146-148 , denotes ,
T13666 142-146 NNP denotes coli
T13665 139-141 NNP denotes E.
T13664 136-138 IN denotes in
T13663 126-135 VBN denotes expressed
T13662 121-125 WRB denotes when
T13661 104-111 NN denotes calpain
T13660 93-103 JJ denotes detectable
T13659 112-120 NN denotes activity
T13658 89-92 DT denotes any
T13657 86-88 IN denotes to
T13656 81-85 NN denotes rise
T13655 268-277 VBN denotes suggested
T13654 72-75 RB denotes not
T13653 68-71 VBD denotes did
T13652 53-58 JJ denotes small
T13651 44-52 VBN denotes modified
T13650 59-67 NNS denotes subunits
T13649 38-43 DT denotes these
T13648 33-37 IN denotes with
T13647 24-32 NNS denotes calpains
T13646 21-23 IN denotes of
T13645 10-20 NN denotes expression
T13644 8-10 , denotes ,
T13643 76-80 VB denotes give
T13642 1-8 RB denotes However
T13641 0-581 sentence denotes However, expression of calpains with these modified small subunits did not give rise to any detectable calpain activity when expressed in E. coli, although their functionality in mammalian cells has yet to be determined (J.S. Elce, unpublished work) It has also been suggested that calpain large subunits alone might provide some activity in eukaryotic cells, although the Zimmerman et al. knockout appears to exclude that possibility, and no calpain activity was observed in our hands when calpain large subunits were expressed alone either in E. coli or in mammalian cells [36].
R3133 T13723 T13721 pobj hands,in
R3135 T13724 T13725 advmod when,expressed
R3136 T13725 T13719 advcl expressed,observed
R3137 T13726 T13727 nmod calpain,subunits
R3138 T13727 T13725 nsubjpass subunits,expressed
R3139 T13728 T13727 amod large,subunits
R3140 T13729 T13725 auxpass were,expressed
R3142 T13730 T13725 advmod alone,expressed
R3143 T13731 T13732 preconj either,in
R3144 T13732 T13725 prep in,expressed
R3146 T13733 T13734 compound E.,coli
R3147 T13734 T13732 pobj coli,in
R3148 T13735 T13732 cc or,in
R3150 T13736 T13732 conj in,in
R3151 T13737 T13738 amod mammalian,cells
R3153 T13738 T13736 pobj cells,in
R3154 T13739 T13740 punct [,36
R3155 T13740 T13725 parataxis 36,expressed
R3157 T13741 T13740 punct ],36
R3158 T13742 T13655 punct .,suggested
R3176 T13642 T13643 advmod However,give
R3177 T13643 T13655 ccomp give,suggested
R3180 T13644 T13643 punct ", ",give
R3184 T13645 T13643 nsubj expression,give
R3190 T13646 T13645 prep of,expression
R3194 T13647 T13646 pobj calpains,of
R3198 T13648 T13647 prep with,calpains
R3201 T13649 T13650 det these,subunits
R3205 T13650 T13648 pobj subunits,with
R3208 T13651 T13650 amod modified,subunits
R3212 T13652 T13650 amod small,subunits
R3216 T13653 T13643 aux did,give
R3219 T13654 T13643 neg not,give
R3222 T13656 T13643 dobj rise,give
R3226 T13657 T13643 prep to,give
R3230 T13658 T13659 det any,activity
R3234 T13659 T13657 pobj activity,to
R3238 T13660 T13659 amod detectable,activity
R3244 T13661 T13659 compound calpain,activity
R3249 T13662 T13663 advmod when,expressed
R3252 T13663 T13643 advcl expressed,give
R3256 T13664 T13663 prep in,expressed
R3259 T13665 T13666 compound E.,coli
R3262 T13666 T13664 pobj coli,in
R3265 T13667 T13643 punct ", ",give
R3269 T13668 T13669 mark although,has
R3270 T13669 T13643 advcl has,give
R3271 T13670 T13671 poss their,functionality
R3274 T13671 T13669 nsubj functionality,has
R3278 T13672 T13671 prep in,functionality
R3281 T13673 T13674 amod mammalian,cells
R3284 T13674 T13672 pobj cells,in
R3286 T13675 T13669 advmod yet,has
R3290 T13676 T13677 aux to,determined
R3291 T13677 T13669 xcomp determined,has
R3294 T13678 T13677 auxpass be,determined
R3298 T13679 T13680 punct (,J.S.
R3301 T13680 T13669 meta J.S.,has
R3304 T13681 T13680 nmod Elce,J.S.
R3308 T13682 T13680 punct ", ",J.S.
R3311 T13683 T13680 amod unpublished,J.S.
R3315 T13684 T13680 nmod work,J.S.
R3319 T13685 T13680 punct ),J.S.
R3322 T13686 T13655 nsubjpass It,suggested
R3324 T13687 T13655 aux has,suggested
R3326 T13688 T13655 advmod also,suggested
R3330 T13689 T13655 auxpass been,suggested
R3334 T13690 T13691 mark that,provide
R3338 T13691 T13655 ccomp provide,suggested
R3342 T13692 T13693 nmod calpain,subunits
R3348 T13693 T13691 nsubj subunits,provide
R3352 T13694 T13693 amod large,subunits
R3355 T13695 T13693 advmod alone,subunits
R3358 T13696 T13691 aux might,provide
R3362 T13697 T13698 det some,activity
R3365 T13698 T13691 dobj activity,provide
R3367 T13699 T13691 prep in,provide
R3371 T13700 T13701 amod eukaryotic,cells
R3375 T13701 T13699 pobj cells,in
R3379 T13702 T13691 punct ", ",provide
R3382 T13703 T13704 mark although,appears
R3386 T13704 T13691 advcl appears,provide
R3390 T13705 T13706 det the,knockout
R3394 T13706 T13704 nsubj knockout,appears
R3400 T13707 T13706 nmod Zimmerman,knockout
R3403 T13708 T13709 advmod et,al.
R3405 T13709 T13707 advmod al.,Zimmerman
R3408 T13710 T13711 aux to,exclude
R3410 T13711 T13704 xcomp exclude,appears
R3412 T13712 T13713 det that,possibility
R3413 T13713 T13711 dobj possibility,exclude
R3415 T13714 T13691 punct ", ",provide
R3418 T13715 T13691 cc and,provide
R3422 T13716 T13717 det no,activity
R3425 T13717 T13719 nsubjpass activity,observed
R3429 T13718 T13717 compound calpain,activity
R3433 T13719 T13691 conj observed,provide
R3436 T13720 T13719 auxpass was,observed
R3440 T13721 T13719 prep in,observed
R3443 T13722 T13723 poss our,hands

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T12277 560-569 NCBITaxon:40674 denotes mammalian
T12276 546-553 NCBITaxon:562 denotes E. coli
T12275 520-529 GO:0010467 denotes expressed
T12274 343-359 CL:0000255 denotes eukaryotic cells
T12273 343-353 NCBITaxon:2759 denotes eukaryotic
T12272 180-189 NCBITaxon:40674 denotes mammalian
T12271 139-146 NCBITaxon:562 denotes E. coli
T12270 126-135 GO:0010467 denotes expressed
T12269 10-20 GO:0010467 denotes expression

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T12548 560-569 NCBITaxon:40674 denotes mammalian
T12547 546-553 NCBITaxon:562 denotes E. coli
T12546 520-529 GO:0010467 denotes expressed
T12545 354-359 CL_GO_EXT:cell denotes cells
T12544 343-359 CL:0000255 denotes eukaryotic cells
T12543 343-353 NCBITaxon:2759 denotes eukaryotic
T12542 190-195 CL_GO_EXT:cell denotes cells
T12541 180-189 NCBITaxon:40674 denotes mammalian
T12540 139-146 NCBITaxon:562 denotes E. coli
T12539 126-135 GO:0010467 denotes expressed
T12538 44-52 SO_EXT:sequence_alteration_process denotes modified
T12537 10-20 GO:0010467 denotes expression
T12549 570-575 CL_GO_EXT:cell denotes cells