PMC:1382200 / 16208-16444 JSONTXT

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    craft-sa-dev

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The inability to isolate Capn2-/- ES cells, in concert with the absence of Capn2-/- embryos beyond the 8-cell stage, suggested that m-calpain activity might be essential for cell viability or the establishment of viable ES cell clones."}

    craft-ca-core-dev

    {"project":"craft-ca-core-dev","denotations":[{"id":"T7655","span":{"begin":221,"end":228},"obj":"CL:0002322"},{"id":"T7654","span":{"begin":104,"end":116},"obj":"UBERON:0019252"},{"id":"T7653","span":{"begin":85,"end":92},"obj":"UBERON:0000922"},{"id":"T7652","span":{"begin":76,"end":81},"obj":"PR:000005015"},{"id":"T7651","span":{"begin":35,"end":43},"obj":"CL:0002322"},{"id":"T7650","span":{"begin":26,"end":31},"obj":"PR:000005015"}],"text":" The inability to isolate Capn2-/- ES cells, in concert with the absence of Capn2-/- embryos beyond the 8-cell stage, suggested that m-calpain activity might be essential for cell viability or the establishment of viable ES cell clones."}

    craft-ca-core-ex-dev

    {"project":"craft-ca-core-ex-dev","denotations":[{"id":"T7703","span":{"begin":229,"end":235},"obj":"SO_EXT:sequence_cloned_entity"},{"id":"T7702","span":{"begin":224,"end":228},"obj":"CL_GO_EXT:cell"},{"id":"T7701","span":{"begin":221,"end":228},"obj":"CL:0002322"},{"id":"T7700","span":{"begin":175,"end":179},"obj":"CL_GO_EXT:cell"},{"id":"T7699","span":{"begin":133,"end":142},"obj":"GO_PR_EXT:calpain_2_complex"},{"id":"T7698","span":{"begin":106,"end":110},"obj":"CL_GO_EXT:cell"},{"id":"T7697","span":{"begin":104,"end":116},"obj":"UBERON:0019252"},{"id":"T7696","span":{"begin":85,"end":92},"obj":"UBERON:0000922"},{"id":"T7695","span":{"begin":83,"end":84},"obj":"SO_EXT:sequence_nullness_or_absence"},{"id":"T7694","span":{"begin":81,"end":82},"obj":"SO_EXT:sequence_nullness_or_absence"},{"id":"T7693","span":{"begin":76,"end":81},"obj":"PR_EXT:000005015"},{"id":"T7692","span":{"begin":38,"end":43},"obj":"CL_GO_EXT:cell"},{"id":"T7691","span":{"begin":35,"end":43},"obj":"CL:0002322"},{"id":"T7690","span":{"begin":33,"end":34},"obj":"SO_EXT:sequence_nullness_or_absence"},{"id":"T7689","span":{"begin":31,"end":32},"obj":"SO_EXT:sequence_nullness_or_absence"},{"id":"T7688","span":{"begin":26,"end":31},"obj":"PR_EXT:000005015"}],"text":" The inability to isolate Capn2-/- ES cells, in concert with the absence of Capn2-/- embryos beyond the 8-cell stage, suggested that m-calpain activity might be essential for cell viability or the establishment of viable ES cell clones."}