PMC:1382200 / 1346-1563 JSONTXT

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{"project":"craft-ca-core-dev","denotations":[{"id":"T571","span":{"begin":45,"end":50},"obj":"PR:000005015"},{"id":"T572","span":{"begin":51,"end":55},"obj":"SO:0000704"},{"id":"T573","span":{"begin":71,"end":83},"obj":"GO:0007566"},{"id":"T574","span":{"begin":84,"end":93},"obj":"UBERON:0000922"},{"id":"T575","span":{"begin":116,"end":122},"obj":"UBERON:0000085"},{"id":"T576","span":{"begin":127,"end":137},"obj":"UBERON:0000358"}],"text":"e conclude that homozygous disruption of the Capn2 gene results in pre-implantation embryonic lethality between the morula and blastocyst stage. This establishes that μ-calpain and m-calpain have distinct functions, a"}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T650","span":{"begin":45,"end":50},"obj":"PR_EXT:000005015"},{"id":"T651","span":{"begin":51,"end":55},"obj":"SO_EXT:0000704"},{"id":"T652","span":{"begin":71,"end":83},"obj":"GO:0007566"},{"id":"T653","span":{"begin":84,"end":93},"obj":"UBERON:0000922"},{"id":"T654","span":{"begin":94,"end":103},"obj":"GO_EXT:fatality_or_lethality"},{"id":"T655","span":{"begin":116,"end":122},"obj":"UBERON:0000085"},{"id":"T656","span":{"begin":127,"end":137},"obj":"UBERON:0000358"},{"id":"T657","span":{"begin":167,"end":176},"obj":"GO_PR_EXT:calpain_1_complex"},{"id":"T658","span":{"begin":181,"end":190},"obj":"GO_PR_EXT:calpain_2_complex"}],"text":"e conclude that homozygous disruption of the Capn2 gene results in pre-implantation embryonic lethality between the morula and blastocyst stage. This establishes that μ-calpain and m-calpain have distinct functions, a"}