PMC:1359074 / 2842-8454 JSON TXT

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2_test

Id	Subject	Object	Predicate	Lexical cue
16462943-15721738-85760951	223-224	15721738	denotes	1
16462943-1425584-85760952	365-366	1425584	denotes	2
16462943-8078769-85760953	367-368	8078769	denotes	3
16462943-8404853-85760954	442-443	8404853	denotes	4
16462943-11504872-85760955	835-836	11504872	denotes	5
16462943-9755172-85760956	837-838	9755172	denotes	6
16462943-11818535-85760957	956-957	11818535	denotes	7
16462943-11818535-85760958	1187-1188	11818535	denotes	7
16462943-7567444-85760959	1404-1405	7567444	denotes	8
16462943-14988021-85760959	1404-1405	14988021	denotes	8
16462943-15527762-85760959	1404-1405	15527762	denotes	8
16462943-15846364-85760959	1404-1405	15846364	denotes	8
16462943-9755172-85760960	1422-1423	9755172	denotes	6
16462943-11702786-85760961	1427-1429	11702786	denotes	13
16462943-10760285-85760962	1444-1446	10760285	denotes	14
16462943-14530442-85760963	1447-1449	14530442	denotes	15
16462943-10760285-85760964	1535-1537	10760285	denotes	14
16462943-10760285-85760965	1673-1675	10760285	denotes	14
16462943-10760285-85760966	1872-1874	10760285	denotes	14
16462943-11310796-85760967	1930-1932	11310796	denotes	16
16462943-11497996-85760968	2268-2270	11497996	denotes	17
16462943-10871404-85760969	2555-2557	10871404	denotes	18
16462943-8622684-85760969	2555-2557	8622684	denotes	18
16462943-9566881-85760969	2555-2557	9566881	denotes	18
16462943-10908341-85760969	2555-2557	10908341	denotes	18
16462943-9887104-85760970	2751-2753	9887104	denotes	22
16462943-12384402-85760971	2958-2960	12384402	denotes	23
16462943-9887104-85760972	3165-3167	9887104	denotes	22
16462943-9887104-85760973	3318-3320	9887104	denotes	22
16462943-2251502-85760974	3543-3545	2251502	denotes	24
16462943-12324650-85760975	3546-3548	12324650	denotes	25
16462943-10192336-85760976	3634-3636	10192336	denotes	26
16462943-2251502-85760977	3728-3730	2251502	denotes	24
16462943-12324650-85760978	3731-3733	12324650	denotes	25
16462943-15730849-85760979	3845-3847	15730849	denotes	27
16462943-15730849-85760980	4138-4140	15730849	denotes	27
16462943-15730849-85760981	4352-4354	15730849	denotes	27
16462943-7567444-85760982	4580-4581	7567444	denotes	8
16462943-14988021-85760982	4580-4581	14988021	denotes	8
16462943-15527762-85760982	4580-4581	15527762	denotes	8
16462943-15846364-85760982	4580-4581	15846364	denotes	8
16462943-9755172-85760983	4598-4599	9755172	denotes	6
16462943-11702786-85760984	4603-4605	11702786	denotes	13
16462943-10760285-85760985	4620-4622	10760285	denotes	14
16462943-14530442-85760986	4623-4625	14530442	denotes	15
16462943-15730849-85760987	4997-4999	15730849	denotes	27
T25472	223-224	15721738	denotes	1
T92399	365-366	1425584	denotes	2
T83652	367-368	8078769	denotes	3
T27842	442-443	8404853	denotes	4
T61683	835-836	11504872	denotes	5
T79059	837-838	9755172	denotes	6
T88037	956-957	11818535	denotes	7
T40137	1187-1188	11818535	denotes	7
T45738	1404-1405	7567444	denotes	8
T82032	1404-1405	14988021	denotes	8
T33694	1404-1405	15527762	denotes	8
T38280	1404-1405	15846364	denotes	8
T90351	1422-1423	9755172	denotes	6
T9372	1427-1429	11702786	denotes	13
T69328	1444-1446	10760285	denotes	14
T86458	1447-1449	14530442	denotes	15
T16581	1535-1537	10760285	denotes	14
T66355	1673-1675	10760285	denotes	14
T42	1872-1874	10760285	denotes	14
T20259	1930-1932	11310796	denotes	16
T43152	2268-2270	11497996	denotes	17
T58158	2555-2557	10871404	denotes	18
T32189	2555-2557	8622684	denotes	18
T90133	2555-2557	9566881	denotes	18
T83229	2555-2557	10908341	denotes	18
T95179	2751-2753	9887104	denotes	22
T53294	2958-2960	12384402	denotes	23
T97722	3165-3167	9887104	denotes	22
T37501	3318-3320	9887104	denotes	22
T20450	3543-3545	2251502	denotes	24
T67689	3546-3548	12324650	denotes	25
T67355	3634-3636	10192336	denotes	26
T4658	3728-3730	2251502	denotes	24
T38161	3731-3733	12324650	denotes	25
T66161	3845-3847	15730849	denotes	27
T44001	4138-4140	15730849	denotes	27
T9633	4352-4354	15730849	denotes	27
T11140	4580-4581	7567444	denotes	8
T59872	4580-4581	14988021	denotes	8
T36493	4580-4581	15527762	denotes	8
T10217	4580-4581	15846364	denotes	8
T1755	4598-4599	9755172	denotes	6
T16819	4603-4605	11702786	denotes	13
T38852	4620-4622	10760285	denotes	14
T5543	4623-4625	14530442	denotes	15
T90570	4997-4999	15730849	denotes	27

pmc-enju-pas

Id	Subject	Object	Predicate	Lexical cue
T2683	5597-5611	NN	denotes	erythropoiesis
T2682	5586-5596	JJ	denotes	definitive
T2681	5583-5585	IN	denotes	in
T2680	5573-5582	NN	denotes	functions
T2679	5568-5572	NN	denotes	Sox6
T2678	5563-5567	IN	denotes	that
T2677	5549-5562	VB	denotes	demonstrating
T2676	5547-5548	-COMMA-	denotes	,
T2675	5542-5547	NN	denotes	liver
T2674	5536-5541	JJ	denotes	fetal
T2673	5532-5535	DT	denotes	the
T2672	5529-5531	IN	denotes	in
T2671	5519-5528	VB	denotes	expressed
T2670	5507-5518	RB	denotes	ectopically
T2669	5504-5506	VB	denotes	is
T2668	5497-5503	NN	denotes	globin
T2667	5494-5496	JJ	denotes	ɛy
T2666	5492-5493	-COMMA-	denotes	,
T2665	5488-5492	NN	denotes	Sox6
T2664	5485-5487	IN	denotes	of
T2663	5477-5484	NN	denotes	absence
T2662	5473-5476	DT	denotes	the
T2661	5470-5472	IN	denotes	In
T2660	5462-5468	NN	denotes	globin
T2659	5459-5461	JJ	denotes	ɛy
T2658	5456-5458	IN	denotes	of
T2657	5448-5455	NN	denotes	pattern
T2656	5437-5447	NN	denotes	expression
T2655	5428-5436	JJ	denotes	opposite
T2654	5424-5427	DT	denotes	the
T2653	5422-5423	-COMMA-	denotes	,
T2652	5417-5422	NN	denotes	liver
T2651	5411-5416	JJ	denotes	fetal
T2650	5408-5410	IN	denotes	in
T2649	5398-5407	VB	denotes	expressed
T2648	5395-5397	VB	denotes	is
T2647	5391-5394	CC	denotes	but
T2646	5389-5390	-COMMA-	denotes	,
T2645	5382-5389	NN	denotes	islands
T2644	5376-5381	NN	denotes	blood
T2643	5372-5375	NN	denotes	sac
T2642	5367-5371	NN	denotes	yolk
T2641	5364-5366	IN	denotes	in
T2640	5354-5363	VB	denotes	expressed
T2639	5350-5353	RB	denotes	not
T2638	5347-5349	VB	denotes	is
T2637	5342-5346	NN	denotes	Sox6
T2636	5340-5341	-COMMA-	denotes	,
T2635	5336-5340	NN	denotes	mice
T2634	5334-5335	-RRB-	denotes	)
T2633	5332-5334	JJ	denotes	WT
T2632	5331-5332	-LRB-	denotes	(
T2631	5321-5330	JJ	denotes	wild-type
T2630	5318-5320	IN	denotes	In
T2629	5303-5316	NN	denotes	transcription
T2628	5299-5302	PRP-DOLLAR-	denotes	its
T2627	5289-5298	VB	denotes	represses
T2626	5285-5288	CC	denotes	and
T2625	5278-5284	NN	denotes	globin
T2624	5275-5277	JJ	denotes	ɛy
T2623	5272-5274	IN	denotes	of
T2622	5263-5271	NN	denotes	promoter
T2621	5254-5262	JJ	denotes	proximal
T2620	5250-5253	DT	denotes	the
T2619	5247-5249	TO	denotes	to
T2618	5241-5246	VB	denotes	binds
T2617	5236-5240	NN	denotes	Sox6
T2616	5231-5235	IN	denotes	that
T2615	5226-5230	VB	denotes	show
T2614	5223-5225	PRP	denotes	We
T2613	5217-5221	NN	denotes	gene
T2612	5210-5216	NN	denotes	globin
T2611	5207-5209	JJ	denotes	ɛy
T2610	5203-5206	DT	denotes	the
T2609	5200-5202	IN	denotes	on
T2608	5195-5199	NN	denotes	Sox6
T2607	5192-5194	IN	denotes	of
T2606	5184-5191	NN	denotes	effects
T2605	5180-5183	DT	denotes	the
T2604	5167-5179	VB	denotes	characterize
T2603	5163-5166	CC	denotes	and
T2602	5154-5162	VB	denotes	describe
T2601	5151-5153	PRP	denotes	we
T2600	5146-5150	RB	denotes	Here
T2599	5140-5144	NN	denotes	gene
T2598	5133-5139	NN	denotes	globin
T2597	5130-5132	JJ	denotes	ɛy
T2596	5120-5129	JJ	denotes	embryonic
T2595	5116-5119	DT	denotes	the
T2594	5113-5115	IN	denotes	of
T2593	5102-5112	NN	denotes	expression
T2592	5097-5101	JJ	denotes	high
T2591	5094-5096	IN	denotes	of
T2590	5082-5093	NN	denotes	persistence
T2589	5078-5081	DT	denotes	the
T2588	5075-5077	VB	denotes	is
T2587	5068-5074	NN	denotes	effect
T2586	5060-5067	JJ	denotes	extreme
T2585	5055-5059	RB	denotes	most
T2584	5051-5054	DT	denotes	The
T2583	5044-5049	NN	denotes	genes
T2582	5037-5043	NN	denotes	globin
T2581	5027-5036	JJ	denotes	embryonic
T2580	5024-5026	IN	denotes	of
T2579	5013-5023	NN	denotes	expression
T2578	5006-5012	JJ	denotes	higher
T2577	5002-5005	CC	denotes	and
T2576	5000-5001	-RRB-	denotes	)
T2575	4999-5000	-RRB-	denotes	]
T2574	4997-4999	CD	denotes	27
T2573	4996-4997	-LRB-	denotes	[
T2572	4984-4995	NN	denotes	bloodstream
T2571	4980-4983	DT	denotes	the
T2570	4971-4979	VB	denotes	entering
T2569	4968-4970	TO	denotes	to
T2568	4962-4967	JJ	denotes	prior
T2567	4952-4961	VB	denotes	enucleate
T2566	4943-4951	RB	denotes	normally
T2565	4938-4942	IN	denotes	that
T2564	4937-4938	-LRB-	denotes	(
T2563	4924-4936	NN	denotes	erythrocytes
T2562	4921-4923	IN	denotes	of
T2561	4910-4920	NN	denotes	maturation
T2560	4902-4909	VB	denotes	delayed
T2559	4894-4901	VB	denotes	include
T2558	4886-4893	NN	denotes	effects
T2557	4880-4885	DT	denotes	These
T2556	4864-4878	NN	denotes	erythropoiesis
T2555	4861-4863	IN	denotes	on
T2554	4853-4860	NN	denotes	effects
T2553	4841-4852	JJ	denotes	pleiotropic
T2552	4834-4840	VB	denotes	exerts
T2551	4829-4833	RB	denotes	also
T2550	4824-4828	NN	denotes	Sox6
T2549	4819-4823	IN	denotes	that
T2548	4810-4818	VB	denotes	describe
T2547	4807-4809	PRP	denotes	we
T2546	4805-4806	-COMMA-	denotes	,
T2545	4800-4805	NN	denotes	study
T2544	4795-4799	DT	denotes	this
T2543	4792-4794	IN	denotes	In
T2542	4789-4790	-RRB-	denotes	]
T2541	4787-4789	CD	denotes	28
T2540	4786-4787	-LRB-	denotes	[
T2539	4778-4785	NN	denotes	lineage
T2538	4771-4777	NN	denotes	marrow
T2537	4766-4770	NN	denotes	bone
T2536	4760-4765	NN	denotes	mouse
T2535	4754-4759	JJ	denotes	adult
T2534	4751-4753	IN	denotes	of
T2533	4739-4750	NN	denotes	progenitors
T2532	4727-4738	JJ	denotes	multipotent
T2531	4722-4726	IN	denotes	with
T2530	4713-4721	VB	denotes	compared
T2529	4711-4712	-RRB-	denotes	)
T2528	4705-4711	NN	denotes	LT-HSC
T2527	4704-4705	-LRB-	denotes	(
T2526	4698-4703	NN	denotes	cells
T2525	4693-4697	NN	denotes	stem
T2524	4679-4692	NN	denotes	hematopoiesis
T2523	4669-4678	JJ	denotes	long-term
T2522	4666-4668	IN	denotes	in
T2521	4654-4665	VB	denotes	upregulated
T2520	4651-4653	VB	denotes	is
T2519	4646-4650	NN	denotes	Sox6
T2518	4641-4645	IN	denotes	that
T2517	4635-4640	VB	denotes	shown
T2516	4631-4634	VB	denotes	was
T2515	4628-4630	PRP	denotes	it
T2514	4626-4627	-COMMA-	denotes	,
T2513	4625-4626	-RRB-	denotes	]
T2512	4620-4625	CD	denotes	14,15
T2511	4619-4620	-LRB-	denotes	[
T2510	4612-4618	NN	denotes	muscle
T2509	4608-4611	CC	denotes	and
T2508	4606-4607	-COMMA-	denotes	,
T2507	4605-4606	-RRB-	denotes	]
T2506	4598-4605	CD	denotes	6,12,13
T2505	4597-4598	-LRB-	denotes	[
T2504	4587-4596	NN	denotes	cartilage
T2503	4585-4586	-COMMA-	denotes	,
T2502	4584-4585	-RRB-	denotes	]
T2501	4580-4584	CD	denotes	8–11
T2500	4579-4580	-LRB-	denotes	[
T2499	4572-4578	NN	denotes	system
T2498	4564-4571	JJ	denotes	nervous
T2497	4556-4563	JJ	denotes	central
T2496	4552-4555	DT	denotes	the
T2495	4549-4551	IN	denotes	of
T2494	4537-4548	NN	denotes	development
T2493	4533-4536	DT	denotes	the
T2492	4530-4532	IN	denotes	in
T2491	4525-4529	NN	denotes	role
T2490	4515-4524	JJ	denotes	important
T2489	4512-4514	DT	denotes	an
T2488	4504-4511	VB	denotes	playing
T2470	4393-4395	IN	denotes	of
T2469	4383-4392	NN	denotes	silencing
T2468	4379-4382	DT	denotes	the
T2467	4374-4378	IN	denotes	that
T2466	4366-4373	VB	denotes	appears
T2465	4363-4365	PRP	denotes	it
T2464	4361-4362	-COMMA-	denotes	,
T2463	4357-4361	RB	denotes	Thus
T2462	4354-4355	-RRB-	denotes	]
T2461	4352-4354	CD	denotes	27
T2460	4351-4352	-LRB-	denotes	[
T2459	4341-4350	VB	denotes	silencing
T2458	4339-4340	RB	denotes	ɛ
T2457	4330-4338	VB	denotes	regulate
T2456	4327-4329	TO	denotes	to
T2455	4325-4326	-RRB-	denotes	)
T2454	4316-4325	NN	denotes	complexes
T2453	4308-4315	NN	denotes	protein
T2452	4305-4307	IN	denotes	of
T2451	4300-4304	NN	denotes	part
T2450	4297-4299	IN	denotes	as
T2449	4296-4297	-LRB-	denotes	(
T2448	4287-4295	NN	denotes	elements
T2447	4283-4286	NN	denotes	DNA
T2446	4277-4282	DT	denotes	these
T2445	4274-4276	TO	denotes	to
T2444	4269-4273	VB	denotes	bind
T2443	4260-4268	RB	denotes	directly
T2442	4257-4259	TO	denotes	to
T2441	4251-4256	VB	denotes	shown
T2440	4247-4250	CC	denotes	and
T2439	4236-4246	VB	denotes	identified
T2438	4231-4235	VB	denotes	been
T2437	4226-4230	VB	denotes	have
T2436	4221-4225	NNP	denotes	DRED
T2435	4217-4220	CC	denotes	and
T2434	4215-4216	-COMMA-	denotes	,
T2433	4208-4215	NN	denotes	COUP-TF
T2432	4206-4207	-COMMA-	denotes	,
T2431	4202-4206	NN	denotes	YY-1
T2430	4200-4201	-COMMA-	denotes	,
T2429	4194-4200	NN	denotes	GATA-1
T2428	4191-4193	IN	denotes	as
T2427	4186-4190	JJ	denotes	such
T2426	4184-4185	-COMMA-	denotes	,
T2425	4177-4184	NN	denotes	factors
T2424	4163-4176	NN	denotes	transcription
T2423	4149-4162	JJ	denotes	corresponding
T2422	4143-4148	PRP-DOLLAR-	denotes	Their
T2421	4140-4141	-RRB-	denotes	]
T2420	4138-4140	CD	denotes	27
T2419	4137-4138	-LRB-	denotes	[
T2418	4128-4136	NN	denotes	promoter
T2417	4123-4127	NN	denotes	gene
T2416	4121-4122	NN	denotes	ɛ
T2415	4114-4120	JJ	denotes	distal
T2414	4110-4113	DT	denotes	the
T2413	4106-4109	CC	denotes	and
T2412	4097-4105	JJ	denotes	proximal
T2411	4093-4096	DT	denotes	the
T2410	4088-4092	CC	denotes	both
T2409	4085-4087	IN	denotes	in
T2408	4074-4084	VB	denotes	identified
T2407	4063-4073	RB	denotes	previously
T2406	4058-4062	VB	denotes	been
T2405	4053-4057	VB	denotes	have
T2404	4045-4052	NN	denotes	process
T2403	4035-4044	NN	denotes	silencing
T2402	4031-4034	DT	denotes	the
T2401	4028-4030	TO	denotes	to
T2400	4018-4027	JJ	denotes	important
T2399	4009-4017	NN	denotes	elements
T2398	4005-4008	NN	denotes	DNA
T2397	3996-4004	JJ	denotes	multiple
T2396	3994-3995	-COMMA-	denotes	,
T2395	3988-3994	NN	denotes	assays
T2394	3975-3987	NN	denotes	transfection
T2393	3970-3974	NN	denotes	cell
T2392	3966-3969	CC	denotes	and
T2391	3959-3965	NN	denotes	models
T2390	3953-3958	NN	denotes	mouse
T2389	3942-3952	JJ	denotes	transgenic
T2388	3939-3941	IN	denotes	in
T2387	3930-3938	NN	denotes	analyses
T2386	3921-3929	NN	denotes	deletion
T2385	3912-3920	NN	denotes	promoter
T2384	3906-3911	VB	denotes	Using
T2383	3894-3904	JJ	denotes	autonomous
T2382	3889-3893	NN	denotes	gene
T2381	3879-3888	RB	denotes	primarily
T2380	3876-3878	VB	denotes	is
T2379	3866-3875	NN	denotes	silencing
T2378	3861-3865	IN	denotes	that
T2377	3850-3860	VB	denotes	suggesting
T2376	3848-3849	-COMMA-	denotes	,
T2375	3847-3848	-RRB-	denotes	]
T2374	3845-3847	CD	denotes	27
T2373	3844-3845	-LRB-	denotes	[
T2372	3834-3843	NN	denotes	sequences
T2371	3825-3833	JJ	denotes	adjacent
T2370	3822-3824	IN	denotes	in
T2369	3819-3821	CC	denotes	or
T2368	3814-3818	NN	denotes	gene
T2367	3812-3813	NN	denotes	ɛ
T2366	3808-3811	DT	denotes	the
T2365	3801-3807	IN	denotes	within
T2364	3797-3800	VB	denotes	are
T2363	3792-3796	NN	denotes	gene
T2362	3785-3791	NN	denotes	globin
T2361	3783-3784	NN	denotes	ɛ
T2360	3779-3782	DT	denotes	the
T2359	3769-3778	VB	denotes	silencing
T2358	3765-3768	IN	denotes	for
T2357	3753-3764	JJ	denotes	responsible
T2356	3744-3752	NN	denotes	elements
T2355	3740-3743	DT	denotes	the
T2354	3736-3739	PDT	denotes	All
T2353	3733-3734	-RRB-	denotes	]
T2352	3728-3733	CD	denotes	24,25
T2351	3727-3728	-LRB-	denotes	[
T2350	3723-3726	NN	denotes	LCR
T2349	3719-3722	DT	denotes	the
T2348	3715-3718	IN	denotes	for
T2347	3703-3714	NN	denotes	competition
T2346	3694-3702	NN	denotes	promoter
T2345	3691-3693	IN	denotes	by
T2344	3680-3690	VB	denotes	controlled
T2343	3677-3679	VB	denotes	is
T2342	3670-3676	NN	denotes	switch
T2341	3661-3669	JJ	denotes	β-globin
T2340	3655-3660	JJ	denotes	adult
T2339	3652-3654	TO	denotes	to
T2338	3643-3651	NN	denotes	γ-globin
T2337	3639-3642	DT	denotes	The
T2336	3636-3637	-RRB-	denotes	]
T2335	3634-3636	CD	denotes	26
T2334	3633-3634	-LRB-	denotes	[
T2333	3619-3632	RB	denotes	competitively
T2332	3609-3618	VB	denotes	regulated
T2331	3606-3608	VB	denotes	be
T2330	3603-3605	TO	denotes	to
T2329	3595-3602	VB	denotes	appears
T2328	3590-3594	RB	denotes	also
T2327	3588-3589	NN	denotes	ɛ
T2326	3573-3587	NN	denotes	erythropoiesis
T2325	3563-3572	JJ	denotes	primitive
T2324	3560-3562	IN	denotes	in
T2323	3551-3559	IN	denotes	although
T2322	3549-3550	-COMMA-	denotes	,
T2321	3548-3549	-RRB-	denotes	]
T2320	3543-3548	CD	denotes	24,25
T2319	3542-3543	-LRB-	denotes	[
T2318	3529-3541	RB	denotes	autonomously
T2317	3520-3528	VB	denotes	silenced
T2316	3516-3519	CC	denotes	and
T2315	3506-3515	VB	denotes	activated
T2314	3503-3505	VB	denotes	is
T2313	3501-3502	NN	denotes	ɛ
T2312	3499-3500	-COMMA-	denotes	,
T2311	3485-3499	NN	denotes	erythropoiesis
T2310	3474-3484	JJ	denotes	definitive
T2309	3471-3473	IN	denotes	In
T2308	3458-3469	RB	denotes	extensively
T2307	3450-3457	VB	denotes	studied
T2306	3445-3449	VB	denotes	been
T2305	3441-3444	VB	denotes	has
T2304	3439-3440	-COMMA-	denotes	,
T2303	3433-3439	NN	denotes	globin
T2302	3431-3432	NN	denotes	ɛ
T2301	3429-3430	-COMMA-	denotes	,
T2300	3418-3429	NN	denotes	counterpart
T2299	3412-3417	JJ	denotes	human
T2298	3408-3411	PRP-DOLLAR-	denotes	its
T2297	3405-3407	IN	denotes	of
T2296	3395-3404	NN	denotes	silencing
T2295	3392-3394	IN	denotes	of
T2294	3382-3391	NN	denotes	mechanism
T2293	3378-3381	DT	denotes	The
T2292	3371-3376	NN	denotes	cells
T2291	3361-3370	JJ	denotes	erythroid
T2290	3350-3360	JJ	denotes	definitive
T2289	3347-3349	IN	denotes	in
T2288	3338-3346	VB	denotes	silenced
T2287	3335-3337	VB	denotes	is
T2286	3330-3334	NN	denotes	gene
T2285	3327-3329	JJ	denotes	ɛy
T2284	3323-3326	DT	denotes	The
T2283	3320-3321	-RRB-	denotes	]
T2282	3318-3320	CD	denotes	22
T2281	3317-3318	-LRB-	denotes	[
T2280	3315-3316	-RRB-	denotes	)
T2279	3310-3315	JJ	denotes	minor
T2278	3306-3309	CC	denotes	and
T2277	3300-3305	JJ	denotes	major
T2276	3298-3299	VB	denotes	β
T2275	3297-3298	-LRB-	denotes	(
T2274	3289-3296	NN	denotes	globins
T2273	3287-3288	JJ	denotes	β
T2272	3281-3286	JJ	denotes	adult
T2271	3273-3280	VB	denotes	express
T2270	3267-3272	NN	denotes	cells
T2269	3257-3266	JJ	denotes	erythroid
T2268	3246-3256	JJ	denotes	definitive
T2267	3240-3245	WRB	denotes	where
T2266	3234-3239	NN	denotes	liver
T2265	3228-3233	JJ	denotes	fetal
T2264	3224-3227	DT	denotes	the
T2263	3221-3223	TO	denotes	to
T2262	3214-3220	NN	denotes	shifts
T2261	3199-3213	NN	denotes	erythropoiesis
T2260	3197-3198	-COMMA-	denotes	,
T2259	3196-3197	-RRB-	denotes	)
T2258	3193-3196	NN	denotes	dpc
T2257	3192-3193	-LRB-	denotes	(
T2256	3185-3191	NN	denotes	coitus
T2255	3180-3184	NN	denotes	post
T2230	3043-3045	IN	denotes	In
T2229	3034-3041	NN	denotes	fashion
T2228	3013-3033	JJ	denotes	development-specific
T2227	3009-3012	CC	denotes	and
T2226	3001-3008	NN	denotes	tissue-
T2225	2999-3000	DT	denotes	a
T2224	2996-2998	IN	denotes	in
T2223	2986-2995	VB	denotes	expressed
T2222	2982-2985	VB	denotes	are
T2221	2976-2981	NN	denotes	genes
T2220	2967-2975	JJ	denotes	β-globin
T2219	2963-2966	DT	denotes	The
T2218	2960-2961	-RRB-	denotes	]
T2217	2958-2960	CD	denotes	23
T2216	2957-2958	-LRB-	denotes	[
T2215	2952-2956	NN	denotes	gene
T2214	2949-2951	JJ	denotes	ɛy
T2213	2945-2948	DT	denotes	the
T2212	2942-2944	IN	denotes	of
T2211	2939-2941	NN	denotes	5′
T2210	2931-2938	JJ	denotes	located
T2209	2928-2930	NN	denotes	kb
T2208	2925-2927	CD	denotes	25
T2207	2920-2924	IN	denotes	over
T2206	2913-2919	VB	denotes	spread
T2205	2907-2912	NN	denotes	sites
T2204	2892-2906	JJ	denotes	hypersensitive
T2203	2883-2891	NN	denotes	nuclease
T2202	2880-2882	IN	denotes	of
T2201	2876-2879	NN	denotes	set
T2200	2874-2875	DT	denotes	a
T2199	2871-2873	IN	denotes	by
T2198	2857-2870	VB	denotes	characterized
T2197	2854-2856	VB	denotes	is
T2196	2849-2853	WDT	denotes	that
T2195	2842-2848	NN	denotes	region
T2194	2834-2841	NN	denotes	control
T2193	2828-2833	NN	denotes	locus
T2192	2824-2827	DT	denotes	the
T2191	2822-2823	-COMMA-	denotes	,
T2190	2815-2822	NN	denotes	element
T2189	2804-2814	JJ	denotes	regulatory
T2188	2802-2803	DT	denotes	a
T2187	2793-2801	VB	denotes	requires
T2186	2787-2792	NN	denotes	genes
T2185	2781-2786	DT	denotes	these
T2184	2778-2780	IN	denotes	of
T2183	2767-2777	NN	denotes	expression
T2182	2756-2766	JJ	denotes	High-level
T2181	2753-2754	-RRB-	denotes	]
T2180	2751-2753	CD	denotes	22
T2179	2750-2751	-LRB-	denotes	[
T2178	2741-2749	NN	denotes	function
T2177	2737-2740	CC	denotes	and
T2176	2727-2736	NN	denotes	structure
T2175	2712-2726	JJ	denotes	organizational
T2174	2709-2711	IN	denotes	in
T2173	2696-2708	NN	denotes	counterparts
T2172	2690-2695	JJ	denotes	human
T2171	2684-2689	PRP-DOLLAR-	denotes	their
T2170	2681-2683	TO	denotes	to
T2169	2670-2680	JJ	denotes	homologous
T2168	2663-2669	RB	denotes	highly
T2167	2659-2662	VB	denotes	are
T2166	2654-2658	PRP	denotes	they
T2165	2650-2653	CC	denotes	and
T2164	2648-2649	CD	denotes	7
T2163	2637-2647	NN	denotes	Chromosome
T2162	2634-2636	IN	denotes	on
T2161	2624-2633	VB	denotes	clustered
T2160	2620-2623	VB	denotes	are
T2159	2618-2619	-RRB-	denotes	}
T2158	2611-2618	JJ	denotes	β-minor
T2157	2607-2610	CC	denotes	and
T2156	2605-2606	-COMMA-	denotes	,
T2155	2598-2605	JJ	denotes	β-major
T2154	2596-2597	-COMMA-	denotes	,
T2153	2593-2596	NN	denotes	βh1
T2152	2591-2592	-COMMA-	denotes	,
T2151	2589-2591	NN	denotes	ɛy
T2150	2588-2589	-LRB-	denotes	{
T2149	2582-2587	NN	denotes	genes
T2148	2573-2581	NN	denotes	β-globin
T2147	2567-2572	NN	denotes	mouse
T2146	2563-2566	DT	denotes	The
T2145	2560-2561	-RRB-	denotes	]
T2144	2555-2560	CD	denotes	18–21
T2143	2554-2555	-LRB-	denotes	[
T2142	2548-2553	NN	denotes	genes
T2141	2539-2547	JJ	denotes	β-globin
T2140	2530-2538	VB	denotes	modulate
T2139	2527-2529	TO	denotes	to
T2138	2521-2526	VB	denotes	shown
T2137	2516-2520	VB	denotes	been
T2136	2511-2515	VB	denotes	have
T2135	2502-2510	NN	denotes	proteins
T2134	2498-2501	NN	denotes	HMG
T2133	2496-2497	-COMMA-	denotes	,
T2132	2484-2496	RB	denotes	Specifically
T2131	2475-2482	NN	denotes	factors
T2130	2464-2474	VB	denotes	associated
T2129	2460-2463	CC	denotes	and
T2128	2456-2459	NN	denotes	DNA
T2127	2453-2455	IN	denotes	of
T2126	2445-2452	NN	denotes	regions
T2125	2437-2444	JJ	denotes	distant
T2124	2428-2436	RB	denotes	together
T2123	2419-2427	VB	denotes	bringing
T2122	2416-2418	IN	denotes	by
T2121	2410-2415	NN	denotes	genes
T2120	2390-2409	JJ	denotes	chromatin-assembled
T2119	2386-2389	CC	denotes	and
T2118	2382-2385	NN	denotes	DNA
T2117	2377-2381	CC	denotes	both
T2116	2374-2376	IN	denotes	on
T2487	4501-4503	TO	denotes	to
T2486	4492-4500	NN	denotes	addition
T2485	4489-4491	IN	denotes	In
T2484	4479-4487	NN	denotes	proteins
T2483	4467-4478	VB	denotes	transacting
T2482	4463-4466	CC	denotes	and
T2481	4454-4462	NN	denotes	elements
T2480	4450-4453	NN	denotes	cis
T2479	4441-4449	JJ	denotes	multiple
T2478	4438-4440	IN	denotes	of
T2477	4430-4437	NN	denotes	network
T2476	4418-4429	JJ	denotes	complicated
T2475	4416-4417	DT	denotes	a
T2474	4407-4415	VB	denotes	involves
T2473	4402-4406	NN	denotes	gene
T2472	4400-4401	NN	denotes	ɛ
T2471	4396-4399	DT	denotes	the
T2115	2365-2373	NN	denotes	function
T2114	2356-2364	NN	denotes	enhancer
T2113	2345-2355	JJ	denotes	long-range
T2112	2337-2344	VB	denotes	mediate
T2111	2333-2336	MD	denotes	can
T2110	2324-2332	NN	denotes	proteins
T2109	2320-2323	NN	denotes	HMG
T2108	2314-2319	JJ	denotes	other
T2107	2310-2313	CC	denotes	and
T2106	2304-2309	DT	denotes	these
T2105	2301-2303	IN	denotes	by
T2104	2291-2300	NN	denotes	structure
T2103	2287-2290	NN	denotes	DNA
T2102	2284-2286	IN	denotes	of
T2101	2273-2283	NN	denotes	Modulation
T2100	2270-2271	-RRB-	denotes	]
T2099	2268-2270	CD	denotes	17
T2098	2267-2268	-LRB-	denotes	[
T2097	2258-2266	NN	denotes	proteins
T2096	2253-2257	NN	denotes	HMG2
T2095	2249-2252	CC	denotes	and
T2094	2244-2248	NN	denotes	HMG1
T2093	2234-2243	VB	denotes	expressed
T2092	2221-2233	RB	denotes	ubiquitously
T2091	2217-2220	DT	denotes	the
T2090	2213-2216	VB	denotes	are
T2089	2211-2212	-COMMA-	denotes	,
T2088	2200-2211	NN	denotes	specificity
T2087	2191-2199	NN	denotes	sequence
T2086	2183-2190	IN	denotes	without
T2085	2179-2182	CC	denotes	but
T2084	2177-2178	-COMMA-	denotes	,
T2083	2174-2177	NN	denotes	DNA
T2082	2169-2173	NN	denotes	bend
T2081	2165-2168	CC	denotes	and
T2080	2158-2164	NN	denotes	groove
T2079	2152-2157	JJ	denotes	minor
T2078	2148-2151	DT	denotes	the
T2077	2145-2147	TO	denotes	to
T2076	2140-2144	VB	denotes	bind
T2075	2130-2139	RB	denotes	similarly
T2074	2125-2129	WDT	denotes	that
T2073	2123-2124	-RRB-	denotes	)
T2072	2117-2123	NN	denotes	family
T2071	2110-2116	NN	denotes	factor
T2070	2096-2109	NN	denotes	transcription
T2069	2092-2095	NN	denotes	Sox
T2068	2088-2091	DT	denotes	the
T2067	2085-2087	IN	denotes	of
T2066	2074-2084	VB	denotes	identified
T2065	2067-2073	NN	denotes	member
T2064	2061-2066	JJ	denotes	first
T2063	2057-2060	DT	denotes	the
T2062	2056-2057	-LRB-	denotes	(
T2061	2052-2055	NN	denotes	Sry
T2060	2049-2051	TO	denotes	to
T2059	2041-2048	VB	denotes	related
T2058	2031-2040	RB	denotes	distantly
T2057	2022-2030	NN	denotes	proteins
T2056	2018-2021	NN	denotes	box
T2055	2014-2017	NN	denotes	HMG
T2054	2010-2013	DT	denotes	the
T2053	2004-2009	IN	denotes	Among
T2052	1992-2002	NN	denotes	phenotypes
T2051	1986-1991	JJ	denotes	other
T2050	1982-1985	DT	denotes	all
T2049	1979-1981	IN	denotes	in
T2048	1968-1978	VB	denotes	implicated
T2047	1965-1967	VB	denotes	is
T2046	1958-1964	NN	denotes	factor
T2045	1944-1957	NN	denotes	transcription
T2044	1939-1943	NN	denotes	Sox6
T2043	1935-1938	DT	denotes	the
T2042	1933-1934	-COMMA-	denotes	,
T2041	1932-1933	-RRB-	denotes	]
T2040	1930-1932	CD	denotes	16
T2039	1929-1930	-LRB-	denotes	[
T2038	1916-1928	NN	denotes	pigmentation
T2037	1913-1915	IN	denotes	in
T2036	1906-1912	RB	denotes	solely
T2035	1896-1905	VB	denotes	functions
T2034	1891-1895	NN	denotes	gene
T2033	1889-1890	NN	denotes	p
T2032	1885-1888	DT	denotes	the
T2031	1877-1884	IN	denotes	Because
T2030	1874-1875	-RRB-	denotes	]
T2029	1872-1874	CD	denotes	14
T2028	1871-1872	-LRB-	denotes	[
T2027	1869-1870	-RRB-	denotes	)
T2026	1858-1869	NN	denotes	breakpoints
T2025	1846-1857	JJ	denotes	chromosomal
T2024	1842-1845	DT	denotes	the
T2023	1839-1841	IN	denotes	of
T2022	1827-1838	NN	denotes	nucleotides
T2021	1820-1826	CD	denotes	50,000
T2020	1813-1819	IN	denotes	within
T2019	1808-1812	NN	denotes	gene
T2018	1802-1807	JJ	denotes	other
T2017	1799-1801	DT	denotes	no
T2016	1795-1798	CC	denotes	and
T2015	1794-1795	-LRB-	denotes	(
T1782	457-460	NN	denotes	Sox
T1781	455-456	-COMMA-	denotes	,
T1780	446-455	RB	denotes	Therefore
T1779	443-444	-RRB-	denotes	]
T1778	442-443	CD	denotes	4
T1777	441-442	-LRB-	denotes	[
T1776	437-440	NN	denotes	DNA
T1775	434-436	IN	denotes	of
T1774	427-433	NN	denotes	groove
T1773	421-426	JJ	denotes	major
T1772	417-420	DT	denotes	the
T1771	410-416	VB	denotes	target
T1770	402-409	NN	denotes	factors
T1769	388-401	NN	denotes	transcription
T1768	382-387	JJ	denotes	other
T1767	377-381	JJ	denotes	most
T1766	371-376	IN	denotes	while
T1765	369-370	-COMMA-	denotes	,
T1764	368-369	-RRB-	denotes	]
T1763	365-368	CD	denotes	2,3
T1762	364-365	-LRB-	denotes	[
T1761	356-363	NN	denotes	changes
T1760	341-355	JJ	denotes	conformational
T1759	335-340	JJ	denotes	local
T1758	332-334	TO	denotes	to
T1757	326-331	VB	denotes	leads
T1756	321-325	WDT	denotes	that
T1755	317-320	NN	denotes	DNA
T1754	313-316	DT	denotes	the
T1753	310-312	IN	denotes	of
T1752	305-309	NN	denotes	bend
T1751	297-304	JJ	denotes	70°–85°
T1750	295-296	DT	denotes	a
T1749	289-294	VB	denotes	cause
T1748	285-288	CC	denotes	and
T1747	281-284	NN	denotes	DNA
T1746	278-280	IN	denotes	of
T1745	271-277	NN	denotes	groove
T1744	265-270	JJ	denotes	minor
T1743	261-264	DT	denotes	the
T1742	258-260	TO	denotes	to
T1741	253-257	VB	denotes	bind
T1740	245-252	NN	denotes	factors
T1739	231-244	NN	denotes	transcription
T1738	227-230	NN	denotes	Sox
T1737	224-225	-RRB-	denotes	]
T1736	223-224	CD	denotes	1
T1735	222-223	-LRB-	denotes	[
T1734	214-221	NN	denotes	binding
T1733	210-213	CC	denotes	and
T1732	198-209	NN	denotes	recognition
T1731	194-197	NN	denotes	DNA
T1730	191-193	IN	denotes	in
T1729	182-190	VB	denotes	involved
T1728	176-181	NN	denotes	acids
T1727	170-175	NN	denotes	amino
T1726	167-169	CD	denotes	79
T1725	164-166	IN	denotes	of
T1724	153-163	VB	denotes	consisting
T1723	151-152	-COMMA-	denotes	,
T1722	145-151	NN	denotes	domain
T1721	143-144	-RRB-	denotes	)
T1720	140-143	NN	denotes	HMG
T1719	139-140	-LRB-	denotes	(
T1718	133-138	NN	denotes	group
T1717	124-132	NN	denotes	mobility
T1716	119-123	JJ	denotes	high
T1715	109-118	VB	denotes	conserved
T1714	105-108	DT	denotes	the
T1713	102-104	IN	denotes	by
T1712	88-101	VB	denotes	characterized
T1711	81-87	NN	denotes	family
T1710	74-80	NN	denotes	factor
T1709	60-73	NN	denotes	transcription
T1708	56-59	NN	denotes	Sox
T1707	52-55	DT	denotes	the
T1706	49-51	IN	denotes	of
T1705	42-48	NN	denotes	member
T2254	3178-3179	NN	denotes	d
T2253	3173-3177	CD	denotes	11.5
T2252	3170-3172	IN	denotes	At
T2251	3167-3168	-RRB-	denotes	]
T2250	3165-3167	CD	denotes	22
T2249	3164-3165	-LRB-	denotes	[
T2248	3156-3163	NN	denotes	globins
T2247	3151-3155	NN	denotes	βh-1
T2246	3147-3150	CC	denotes	and
T2245	3144-3146	JJ	denotes	ɛy
T2244	3136-3143	VB	denotes	express
T2243	3130-3135	NN	denotes	cells
T2242	3120-3129	JJ	denotes	erythroid
T2241	3110-3119	JJ	denotes	primitive
T2240	3104-3109	WRB	denotes	where
T2239	3100-3103	NN	denotes	sac
T2238	3095-3099	NN	denotes	yolk
T2237	3085-3094	JJ	denotes	embryonic
T2236	3081-3084	DT	denotes	the
T2235	3078-3080	IN	denotes	in
T2234	3067-3077	VB	denotes	originates
T2233	3052-3066	NN	denotes	erythropoiesis
T2232	3050-3051	-COMMA-	denotes	,
T2231	3046-3050	NN	denotes	mice
T1972	1560-1565	NN	denotes	p100H
T1971	1556-1559	IN	denotes	for
T1970	1545-1555	JJ	denotes	homozygous
T1969	1540-1544	NN	denotes	Mice
T1968	1537-1538	-RRB-	denotes	]
T1967	1535-1537	CD	denotes	14
T1966	1534-1535	-LRB-	denotes	[
T1965	1523-1533	NN	denotes	laboratory
T1964	1519-1522	PRP-DOLLAR-	denotes	our
T1963	1516-1518	IN	denotes	in
T1962	1505-1515	VB	denotes	identified
T1961	1500-1504	VB	denotes	been
T1960	1489-1499	RB	denotes	previously
T1959	1485-1488	VB	denotes	has
T1958	1483-1484	-RRB-	denotes	)
T1957	1478-1483	NN	denotes	p100H
T1956	1477-1478	-LRB-	denotes	(
T1955	1471-1476	NN	denotes	mouse
T1954	1464-1470	JJ	denotes	mutant
T1953	1454-1463	JJ	denotes	Sox6-null
T1952	1452-1453	DT	denotes	A
T1951	1449-1450	-RRB-	denotes	]
T1950	1444-1449	CD	denotes	14,15
T1949	1443-1444	-LRB-	denotes	[
T1948	1436-1442	NN	denotes	muscle
T1947	1432-1435	CC	denotes	and
T1946	1430-1431	-COMMA-	denotes	,
T1945	1429-1430	-RRB-	denotes	]
T1944	1422-1429	CD	denotes	6,12,13
T1943	1421-1422	-LRB-	denotes	[
T1942	1411-1420	NN	denotes	cartilage
T1941	1409-1410	-COMMA-	denotes	,
T1940	1408-1409	-RRB-	denotes	]
T1939	1404-1408	CD	denotes	8–11
T1938	1403-1404	-LRB-	denotes	[
T1937	1396-1402	NN	denotes	system
T1936	1388-1395	JJ	denotes	nervous
T1935	1380-1387	JJ	denotes	central
T1934	1376-1379	DT	denotes	the
T1933	1373-1375	IN	denotes	of
T1932	1361-1372	NN	denotes	development
T1931	1357-1360	DT	denotes	the
T1930	1354-1356	IN	denotes	in
T1929	1349-1353	NN	denotes	role
T1928	1347-1348	DT	denotes	a
T1927	1341-1346	VB	denotes	plays
T1926	1336-1340	WDT	denotes	that
T1925	1327-1335	NN	denotes	molecule
T1924	1316-1326	JJ	denotes	regulatory
T1923	1306-1315	JJ	denotes	important
T1922	1303-1305	DT	denotes	an
T1921	1300-1302	VB	denotes	is
T1920	1295-1299	NN	denotes	Sox6
T1919	1290-1294	IN	denotes	that
T1918	1277-1289	VB	denotes	demonstrated
T1917	1272-1276	VB	denotes	have
T1916	1264-1271	NN	denotes	studies
T1915	1255-1263	JJ	denotes	previous
T1914	1253-1254	-COMMA-	denotes	,
T1913	1243-1253	NN	denotes	expression
T1912	1238-1242	NN	denotes	gene
T1911	1227-1237	VB	denotes	regulating
T1910	1224-1226	IN	denotes	in
T1909	1214-1223	NN	denotes	functions
T1908	1209-1213	NN	denotes	Sox6
T1907	1205-1208	WRB	denotes	how
T1906	1202-1204	IN	denotes	of
T1905	1191-1201	RB	denotes	Regardless
T1904	1188-1189	-RRB-	denotes	]
T1903	1187-1188	CD	denotes	7
T1902	1186-1187	-LRB-	denotes	[
T1901	1177-1185	NN	denotes	proteins
T1900	1171-1176	DT	denotes	these
T1899	1168-1170	IN	denotes	of
T1898	1160-1167	NN	denotes	overlap
T1897	1149-1159	JJ	denotes	functional
T1896	1138-1148	VB	denotes	indicating
T1895	1136-1137	-COMMA-	denotes	,
T1894	1128-1136	NN	denotes	splicing
T1893	1119-1127	VB	denotes	restored
T1892	1110-1118	NN	denotes	extracts
T1891	1106-1109	DT	denotes	the
T1890	1103-1105	IN	denotes	in
T1889	1099-1102	NN	denotes	Sry
T1888	1096-1098	CC	denotes	or
T1887	1094-1095	-COMMA-	denotes	,
T1886	1090-1094	NN	denotes	Sox9
T1885	1088-1089	-COMMA-	denotes	,
T1884	1084-1088	NN	denotes	Sox6
T1883	1077-1083	DT	denotes	either
T1882	1074-1076	IN	denotes	of
T1881	1067-1073	NN	denotes	domain
T1880	1063-1066	NN	denotes	HMG
T1879	1059-1062	DT	denotes	the
T1878	1056-1058	IN	denotes	of
T1877	1045-1055	NN	denotes	expression
T1876	1041-1044	CC	denotes	and
T1875	1039-1040	-COMMA-	denotes	,
T1874	1029-1039	NN	denotes	substrates
T1873	1020-1028	JJ	denotes	multiple
T1872	1017-1019	IN	denotes	of
T1871	1008-1016	NN	denotes	splicing
T1870	1000-1007	VB	denotes	blocked
T1869	991-999	NN	denotes	extracts
T1868	986-990	NN	denotes	cell
T1867	981-985	NN	denotes	HeLa
T1866	978-980	IN	denotes	in
T1865	973-977	NN	denotes	Sox6
T1864	970-972	IN	denotes	of
T1863	960-969	NN	denotes	Depletion
T1862	957-958	-RRB-	denotes	]
T1861	956-957	CD	denotes	7
T1860	955-956	-LRB-	denotes	[
T1859	946-954	NN	denotes	splicing
T1858	937-945	JJ	denotes	pre-mRNA
T1857	934-936	IN	denotes	in
T1856	921-933	VB	denotes	participates
T1855	916-920	WDT	denotes	that
T1854	909-915	NN	denotes	factor
T1853	900-908	NN	denotes	splicing
T1852	892-899	JJ	denotes	general
T1851	890-891	DT	denotes	a
T1850	887-889	IN	denotes	as
T1849	883-886	VB	denotes	act
T1848	880-882	TO	denotes	to
T1847	874-879	VB	denotes	shown
T1846	869-873	VB	denotes	been
T1845	864-868	RB	denotes	also
T1844	860-863	VB	denotes	has
T1843	855-859	NN	denotes	Sox6
T1842	853-854	-COMMA-	denotes	,
T1841	841-853	RB	denotes	Intriguingly
T1840	838-839	-RRB-	denotes	]
T1839	835-838	CD	denotes	5,6
T1838	834-835	-LRB-	denotes	[
T1837	826-833	NN	denotes	context
T1836	817-825	NN	denotes	promoter
T1835	810-816	NN	denotes	target
T1834	806-809	PRP-DOLLAR-	denotes	its
T1833	802-805	CC	denotes	and
T1832	790-801	NN	denotes	interactors
T1831	786-789	PRP-DOLLAR-	denotes	its
T1830	783-785	IN	denotes	on
T1829	773-782	VB	denotes	depending
T1828	771-772	-COMMA-	denotes	,
T1827	762-771	NN	denotes	repressor
T1826	760-761	DT	denotes	a
T1825	757-759	CC	denotes	or
T1824	747-756	NN	denotes	activator
T1823	744-746	DT	denotes	an
T1822	737-743	CC	denotes	either
T1821	734-736	IN	denotes	as
T1820	730-733	VB	denotes	act
T1819	727-729	TO	denotes	to
T1818	722-726	JJ	denotes	able
T1817	719-721	VB	denotes	be
T1816	716-718	TO	denotes	to
T1815	707-715	VB	denotes	reported
T1814	702-706	VB	denotes	been
T1813	698-701	VB	denotes	has
T1812	693-697	NN	denotes	Sox6
T1811	682-691	NN	denotes	complexes
T1810	669-681	NN	denotes	multiprotein
T1809	661-668	VB	denotes	defined
T1808	650-660	RB	denotes	sterically
T1807	648-649	-COMMA-	denotes	,
T1806	642-648	JJ	denotes	active
T1805	629-641	RB	denotes	biologically
T1804	624-628	IN	denotes	into
T1803	616-623	NN	denotes	factors
T1802	602-615	NN	denotes	transcription
T1801	592-601	JJ	denotes	DNA-bound
T1800	586-591	JJ	denotes	other
T1799	575-585	VB	denotes	assembling
T1798	571-574	CC	denotes	and
T1797	561-570	NN	denotes	structure
T1796	551-560	NN	denotes	chromatin
T1795	545-550	JJ	denotes	local
T1794	534-544	VB	denotes	organizing
T1793	531-533	IN	denotes	by
T1792	522-530	NN	denotes	proteins
T1791	508-521	JJ	denotes	architectural
T1790	505-507	IN	denotes	as
T1789	496-504	NN	denotes	function
T1788	490-495	PRP-DOLLAR-	denotes	their
T1787	487-489	IN	denotes	of
T1786	482-486	NN	denotes	part
T1784	470-473	MD	denotes	may
T1783	461-469	NN	denotes	proteins
T2006	1751-1759	VB	denotes	disrupts
T2005	1746-1750	WDT	denotes	that
T2004	1736-1745	NN	denotes	inversion
T2003	1734-1735	CD	denotes	7
T2002	1723-1733	NN	denotes	Chromosome
T2001	1721-1722	DT	denotes	a
T2000	1716-1720	IN	denotes	with
T1999	1705-1715	VB	denotes	associated
T1998	1702-1704	VB	denotes	is
T1997	1695-1701	NN	denotes	allele
T1996	1688-1694	JJ	denotes	mutant
T1995	1682-1687	NN	denotes	p100H
T1994	1678-1681	DT	denotes	The
T1993	1675-1676	-RRB-	denotes	]
T1992	1673-1675	CD	denotes	14
T1991	1672-1673	-LRB-	denotes	[
T1990	1666-1671	NN	denotes	birth
T1989	1660-1665	IN	denotes	after
T1988	1657-1659	NN	denotes	wk
T1987	1655-1656	CD	denotes	2
T1986	1648-1654	IN	denotes	within
T1985	1644-1647	VB	denotes	die
T1984	1640-1643	CC	denotes	and
T1983	1638-1639	-COMMA-	denotes	,
T1982	1633-1638	NN	denotes	block
T1981	1627-1632	NN	denotes	heart
T1980	1608-1626	JJ	denotes	arterioventricular
T1979	1604-1607	CC	denotes	and
T1978	1595-1603	NN	denotes	myopathy
T1977	1587-1594	VB	denotes	develop
T1976	1585-1586	-COMMA-	denotes	,
T1975	1579-1585	NN	denotes	growth
T1974	1571-1578	VB	denotes	delayed
T1973	1566-1570	VB	denotes	show
T2014	1789-1793	NN	denotes	gene
T2013	1784-1788	NN	denotes	Sox6
T2012	1780-1783	DT	denotes	the
T2011	1776-1779	CC	denotes	and
T2010	1771-1775	NN	denotes	gene
T2009	1769-1770	NN	denotes	p
T2008	1765-1768	DT	denotes	the
T2007	1760-1764	CC	denotes	both
T1704	40-41	DT	denotes	a
T1703	37-39	VB	denotes	is
T1702	35-36	-RRB-	denotes	)
T1701	31-35	NN	denotes	Sox6
T1700	30-31	-LRB-	denotes	(
T1699	26-29	NN	denotes	box
T1698	22-25	NN	denotes	HMG
T1697	17-21	NN	denotes	type
T1696	13-16	NN	denotes	Sry
T1785	474-481	VB	denotes	perform
R811	T1705	T1704	arg1Of	member,a
R812	T1705	T1706	arg1Of	member,of
R813	T1711	T1706	arg2Of	family,of
R814	T1711	T1707	arg1Of	family,the
R815	T1711	T1708	arg1Of	family,Sox
R816	T1711	T1709	arg1Of	family,transcription
R817	T1711	T1710	arg1Of	family,factor
R818	T1711	T1712	arg2Of	family,characterized
R819	T1720	T1719	arg2Of	HMG,(
R820	T1721	T1719	arg3Of	),(
R821	T1722	T1712	arg1Of	domain,characterized
R822	T1722	T1713	arg2Of	domain,by
R823	T1722	T1714	arg1Of	domain,the
R824	T1722	T1715	arg2Of	domain,conserved
R825	T1722	T1716	arg1Of	domain,high
R826	T1722	T1717	arg1Of	domain,mobility
R827	T1722	T1718	arg1Of	domain,group
R828	T1722	T1719	arg1Of	domain,(
R829	T1722	T1723	arg1Of	domain,","
R830	T1722	T1724	arg1Of	domain,consisting
R831	T1724	T1725	arg1Of	consisting,of
R832	T1728	T1725	arg2Of	acids,of
R833	T1728	T1726	arg1Of	acids,79
R834	T1728	T1727	arg1Of	acids,amino
R835	T1728	T1729	arg2Of	acids,involved
R836	T1729	T1730	arg1Of	involved,in
R837	T1729	T1735	arg1Of	involved,[
R838	T1732	T1733	arg1Of	recognition,and
R839	T1733	T1730	arg2Of	and,in
R840	T1733	T1731	arg1Of	and,DNA
R841	T1734	T1733	arg2Of	binding,and
R842	T1736	T1735	arg2Of	1,[
R843	T1737	T1735	arg3Of	],[
R844	T1740	T1738	arg1Of	factors,Sox
R845	T1740	T1739	arg1Of	factors,transcription
R846	T1740	T1741	arg1Of	factors,bind
R847	T1740	T1749	arg1Of	factors,cause
R848	T1741	T1742	arg1Of	bind,to
R849	T1741	T1748	arg1Of	bind,and
R850	T1745	T1742	arg2Of	groove,to
R851	T1745	T1743	arg1Of	groove,the
R852	T1745	T1744	arg1Of	groove,minor
R853	T1745	T1746	arg1Of	groove,of
R854	T1747	T1746	arg2Of	DNA,of
R855	T1749	T1748	arg2Of	cause,and
R856	T1752	T1749	arg2Of	bend,cause
R857	T1752	T1750	arg1Of	bend,a
R858	T1752	T1751	arg1Of	bend,70°–85°
R859	T1752	T1753	arg1Of	bend,of
R860	T1755	T1753	arg2Of	DNA,of
R861	T1755	T1754	arg1Of	DNA,the
R862	T1755	T1756	arg1Of	DNA,that
R863	T1755	T1757	arg1Of	DNA,leads
R864	T1757	T1758	arg1Of	leads,to
R865	T1757	T1765	arg1Of	leads,","
R866	T1757	T1766	arg1Of	leads,while
R867	T1761	T1758	arg2Of	changes,to
R868	T1761	T1759	arg1Of	changes,local
R869	T1761	T1760	arg1Of	changes,conformational
R870	T1761	T1762	arg1Of	changes,[
R871	T1763	T1762	arg2Of	"2,3",[
R872	T1764	T1762	arg3Of	],[
R873	T1770	T1767	arg1Of	factors,most
R874	T1770	T1768	arg1Of	factors,other
R875	T1770	T1769	arg1Of	factors,transcription
R876	T1770	T1771	arg1Of	factors,target
R877	T1771	T1766	arg2Of	target,while
R878	T1771	T1777	arg1Of	target,[
R879	T1774	T1771	arg2Of	groove,target
R880	T1774	T1772	arg1Of	groove,the
R881	T1774	T1773	arg1Of	groove,major
R882	T1774	T1775	arg1Of	groove,of
R883	T1776	T1775	arg2Of	DNA,of
R884	T1778	T1777	arg2Of	4,[
R885	T1779	T1777	arg3Of	],[
R886	T1783	T1782	arg1Of	proteins,Sox
R887	T1783	T1784	arg1Of	proteins,may
R888	T1783	T1785	arg1Of	proteins,perform
R889	T1783	T1794	arg1Of	proteins,organizing
R890	T1785	T1780	arg1Of	perform,Therefore
R891	T1785	T1781	arg1Of	perform,","
R892	T1785	T1784	arg2Of	perform,may
R893	T1785	T1790	arg1Of	perform,as
R894	T1785	T1793	arg1Of	perform,by
R895	T1786	T1785	arg2Of	part,perform
R896	T1786	T1787	arg1Of	part,of
R897	T1789	T1787	arg2Of	function,of
R898	T1789	T1788	arg1Of	function,their
R899	T1792	T1790	arg2Of	proteins,as
R900	T1792	T1791	arg1Of	proteins,architectural
R901	T1794	T1793	arg2Of	organizing,by
R902	T1797	T1795	arg1Of	structure,local
R903	T1797	T1796	arg1Of	structure,chromatin
R904	T1797	T1798	arg1Of	structure,and
R905	T1798	T1794	arg2Of	and,organizing
R906	T1798	T1804	arg1Of	and,into
R907	T1803	T1798	arg2Of	factors,and
R908	T1803	T1799	arg1Of	factors,assembling
R909	T1803	T1800	arg1Of	factors,other
R910	T1803	T1801	arg1Of	factors,DNA-bound
R911	T1803	T1802	arg1Of	factors,transcription
R912	T1806	T1805	arg1Of	active,biologically
R913	T1806	T1807	arg1Of	active,","
R914	T1809	T1807	arg2Of	defined,","
R915	T1809	T1808	arg1Of	defined,sterically
R916	T1811	T1804	arg2Of	complexes,into
R917	T1811	T1806	arg1Of	complexes,active
R918	T1811	T1809	arg1Of	complexes,defined
R919	T1811	T1810	arg1Of	complexes,multiprotein
R920	T1812	T1813	arg1Of	Sox6,has
R921	T1812	T1814	arg1Of	Sox6,been
R922	T1812	T1815	arg2Of	Sox6,reported
R923	T1812	T1817	arg1Of	Sox6,be
R924	T1812	T1818	arg1Of	Sox6,able
R925	T1812	T1820	arg1Of	Sox6,act
R926	T1815	T1813	arg2Of	reported,has
R927	T1815	T1814	arg2Of	reported,been
R928	T1817	T1815	arg3Of	be,reported
R929	T1817	T1816	arg1Of	be,to
R930	T1818	T1817	arg2Of	able,be
R931	T1820	T1818	arg2Of	act,able
R932	T1820	T1819	arg1Of	act,to
R933	T1820	T1821	arg1Of	act,as
R934	T1820	T1828	arg1Of	act,","
R935	T1820	T1829	arg1Of	act,depending
R936	T1824	T1823	arg1Of	activator,an
R937	T1824	T1825	arg1Of	activator,or
R938	T1825	T1821	arg2Of	or,as
R939	T1825	T1822	arg1Of	or,either
R940	T1827	T1825	arg2Of	repressor,or
R941	T1827	T1826	arg1Of	repressor,a
R942	T1830	T1829	arg2Of	on,depending
R943	T1832	T1831	arg1Of	interactors,its
R944	T1832	T1833	arg1Of	interactors,and
R945	T1833	T1830	arg2Of	and,on
R946	T1837	T1833	arg2Of	context,and
R947	T1837	T1834	arg1Of	context,its
R948	T1837	T1835	arg1Of	context,target
R949	T1837	T1836	arg1Of	context,promoter
R950	T1837	T1838	arg1Of	context,[
R951	T1839	T1838	arg2Of	"5,6",[
R952	T1840	T1838	arg3Of	],[
R953	T1843	T1844	arg1Of	Sox6,has
R954	T1843	T1846	arg1Of	Sox6,been
R955	T1843	T1847	arg2Of	Sox6,shown
R956	T1843	T1849	arg1Of	Sox6,act
R957	T1847	T1841	arg1Of	shown,Intriguingly
R958	T1847	T1842	arg1Of	shown,","
R959	T1847	T1844	arg2Of	shown,has
R960	T1847	T1845	arg1Of	shown,also
R961	T1847	T1846	arg2Of	shown,been
R962	T1849	T1847	arg3Of	act,shown
R963	T1849	T1848	arg1Of	act,to
R964	T1849	T1850	arg1Of	act,as
R965	T1854	T1850	arg2Of	factor,as
R966	T1854	T1851	arg1Of	factor,a
R967	T1854	T1852	arg1Of	factor,general
R968	T1854	T1853	arg1Of	factor,splicing
R969	T1854	T1855	arg1Of	factor,that
R970	T1854	T1856	arg1Of	factor,participates
R971	T1856	T1857	arg1Of	participates,in
R972	T1859	T1857	arg2Of	splicing,in
R973	T1859	T1858	arg1Of	splicing,pre-mRNA
R974	T1859	T1860	arg1Of	splicing,[
R975	T1861	T1860	arg2Of	7,[
R976	T1862	T1860	arg3Of	],[
R977	T1863	T1864	arg1Of	Depletion,of
R978	T1863	T1866	arg1Of	Depletion,in
R979	T1863	T1870	arg1Of	Depletion,blocked
R980	T1865	T1864	arg2Of	Sox6,of
R981	T1869	T1866	arg2Of	extracts,in
R982	T1869	T1867	arg1Of	extracts,HeLa
R983	T1869	T1868	arg1Of	extracts,cell
R984	T1870	T1876	arg1Of	blocked,and
R985	T1871	T1870	arg2Of	splicing,blocked
R986	T1871	T1872	arg1Of	splicing,of
R987	T1874	T1872	arg2Of	substrates,of
R988	T1874	T1873	arg1Of	substrates,multiple
R989	T1876	T1875	arg1Of	and,","
R990	T1876	T1896	modOf	and,indicating
R991	T1876	T1902	arg1Of	and,[
R992	T1877	T1878	arg1Of	expression,of
R993	T1877	T1893	arg1Of	expression,restored
R994	T1881	T1878	arg2Of	domain,of
R995	T1881	T1879	arg1Of	domain,the
R996	T1881	T1880	arg1Of	domain,HMG
R997	T1881	T1882	arg1Of	domain,of
R998	T1881	T1890	arg1Of	domain,in
R999	T1884	T1885	arg1Of	Sox6,","
R1000	T1885	T1888	arg1Of	",",or
R1001	T1886	T1885	arg2Of	Sox9,","
R1002	T1888	T1882	arg2Of	or,of
R1003	T1888	T1883	arg1Of	or,either
R1004	T1888	T1887	arg1Of	or,","
R1005	T1889	T1888	arg2Of	Sry,or
R1006	T1892	T1890	arg2Of	extracts,in
R1007	T1892	T1891	arg1Of	extracts,the
R1008	T1893	T1876	arg2Of	restored,and
R1009	T1893	T1895	arg1Of	restored,","
R1010	T1894	T1893	arg2Of	splicing,restored
R1011	T1898	T1896	arg2Of	overlap,indicating
R1012	T1898	T1897	arg1Of	overlap,functional
R1013	T1898	T1899	arg1Of	overlap,of
R1014	T1901	T1899	arg2Of	proteins,of
R1015	T1901	T1900	arg1Of	proteins,these
R1016	T1903	T1902	arg2Of	7,[
R1017	T1904	T1902	arg3Of	],[
R1018	T1905	T1906	arg1Of	Regardless,of
R1019	T1907	T1906	arg2Of	how,of
R1020	T1909	T1908	arg1Of	functions,Sox6
R1021	T1909	T1910	arg1Of	functions,in
R1022	T1909	T1911	arg1Of	functions,regulating
R1023	T1911	T1907	arg1Of	regulating,how
R1024	T1913	T1911	arg2Of	expression,regulating
R1025	T1913	T1912	arg1Of	expression,gene
R1026	T1916	T1915	arg1Of	studies,previous
R1027	T1916	T1917	arg1Of	studies,have
R1028	T1916	T1918	arg1Of	studies,demonstrated
R1029	T1918	T1905	arg1Of	demonstrated,Regardless
R1030	T1918	T1914	arg1Of	demonstrated,","
R1031	T1918	T1917	arg2Of	demonstrated,have
R1032	T1920	T1921	arg1Of	Sox6,is
R1033	T1921	T1918	arg2Of	is,demonstrated
R1034	T1921	T1919	arg1Of	is,that
R1035	T1925	T1921	arg2Of	molecule,is
R1036	T1925	T1922	arg1Of	molecule,an
R1037	T1925	T1923	arg1Of	molecule,important
R1038	T1925	T1924	arg1Of	molecule,regulatory
R1039	T1925	T1926	arg1Of	molecule,that
R1040	T1925	T1927	arg1Of	molecule,plays
R1041	T1927	T1930	arg1Of	plays,in
R1042	T1929	T1927	arg2Of	role,plays
R1043	T1929	T1928	arg1Of	role,a
R1044	T1932	T1933	arg1Of	development,of
R1045	T1932	T1941	arg1Of	development,","
R1046	T1937	T1933	arg2Of	system,of
R1047	T1937	T1934	arg1Of	system,the
R1048	T1937	T1935	arg1Of	system,central
R1049	T1937	T1936	arg1Of	system,nervous
R1050	T1937	T1938	arg1Of	system,[
R1051	T1939	T1938	arg2Of	8–11,[
R1052	T1940	T1938	arg3Of	],[
R1053	T1941	T1947	arg1Of	",",and
R1054	T1942	T1941	arg2Of	cartilage,","
R1055	T1942	T1943	arg1Of	cartilage,[
R1056	T1944	T1943	arg2Of	"6,12,13",[
R1057	T1945	T1943	arg3Of	],[
R1058	T1947	T1930	arg2Of	and,in
R1059	T1947	T1931	arg1Of	and,the
R1060	T1947	T1946	arg1Of	and,","
R1061	T1948	T1947	arg2Of	muscle,and
R1062	T1948	T1949	arg1Of	muscle,[
R1063	T1950	T1949	arg2Of	"14,15",[
R1064	T1951	T1949	arg3Of	],[
R1065	T1955	T1952	arg1Of	mouse,A
R1066	T1955	T1953	arg1Of	mouse,Sox6-null
R1067	T1955	T1954	arg1Of	mouse,mutant
R1068	T1955	T1956	arg1Of	mouse,(
R1069	T1955	T1959	arg1Of	mouse,has
R1070	T1955	T1961	arg1Of	mouse,been
R1071	T1955	T1962	arg2Of	mouse,identified
R1072	T1957	T1956	arg2Of	p100H,(
R1073	T1958	T1956	arg3Of	),(
R1074	T1962	T1959	arg2Of	identified,has
R1075	T1962	T1960	arg1Of	identified,previously
R1076	T1962	T1961	arg2Of	identified,been
R1077	T1962	T1963	arg1Of	identified,in
R1078	T1965	T1963	arg2Of	laboratory,in
R1079	T1965	T1964	arg1Of	laboratory,our
R1080	T1965	T1966	arg1Of	laboratory,[
R1081	T1967	T1966	arg2Of	14,[
R1082	T1968	T1966	arg3Of	],[
R1083	T1969	T1970	arg1Of	Mice,homozygous
R1084	T1969	T1973	arg1Of	Mice,show
R1085	T1969	T1977	arg1Of	Mice,develop
R1086	T1969	T1985	arg1Of	Mice,die
R1087	T1970	T1971	arg1Of	homozygous,for
R1088	T1972	T1971	arg2Of	p100H,for
R1089	T1973	T1976	arg1Of	show,","
R1090	T1975	T1973	arg2Of	growth,show
R1091	T1975	T1974	arg2Of	growth,delayed
R1092	T1976	T1984	arg1Of	",",and
R1093	T1977	T1976	arg2Of	develop,","
R1094	T1978	T1979	arg1Of	myopathy,and
R1095	T1980	T1979	arg2Of	arterioventricular,and
R1096	T1982	T1977	arg2Of	block,develop
R1097	T1982	T1978	arg1Of	block,myopathy
R1098	T1982	T1980	arg1Of	block,arterioventricular
R1099	T1982	T1981	arg1Of	block,heart
R1100	T1984	T1983	arg1Of	and,","
R1101	T1984	T1991	arg1Of	and,[
R1102	T1985	T1984	arg2Of	die,and
R1103	T1985	T1986	arg1Of	die,within
R1104	T1985	T1989	arg1Of	die,after
R1105	T1988	T1986	arg2Of	wk,within
R1106	T1988	T1987	arg1Of	wk,2
R1107	T1990	T1989	arg2Of	birth,after
R1108	T1992	T1991	arg2Of	14,[
R1109	T1993	T1991	arg3Of	],[
R1110	T1997	T1994	arg1Of	allele,The
R1111	T1997	T1995	arg1Of	allele,p100H
R1112	T1997	T1996	arg1Of	allele,mutant
R1113	T1997	T1998	arg1Of	allele,is
R1114	T1997	T1999	arg2Of	allele,associated
R1115	T1999	T1998	arg2Of	associated,is
R1116	T1999	T2000	arg1Of	associated,with
R1117	T2004	T2000	arg2Of	inversion,with
R1118	T2004	T2001	arg1Of	inversion,a
R1119	T2004	T2002	arg1Of	inversion,Chromosome
R1120	T2004	T2003	arg1Of	inversion,7
R1121	T2004	T2005	arg1Of	inversion,that
R1122	T2004	T2006	arg1Of	inversion,disrupts
R1123	T2006	T2028	arg1Of	disrupts,[
R1124	T2010	T2008	arg1Of	gene,the
R1125	T2010	T2009	arg1Of	gene,p
R1126	T2010	T2011	arg1Of	gene,and
R1127	T2011	T2006	arg2Of	and,disrupts
R1128	T2011	T2007	arg1Of	and,both
R1129	T2014	T2011	arg2Of	gene,and
R1130	T2014	T2012	arg1Of	gene,the
R1131	T2014	T2013	arg1Of	gene,Sox6
R1132	T2014	T2015	arg1Of	gene,(
R1133	T2019	T2015	arg2Of	gene,(
R1134	T2019	T2016	arg1Of	gene,and
R1135	T2019	T2017	arg1Of	gene,no
R1136	T2019	T2018	arg1Of	gene,other
R1137	T2019	T2020	arg1Of	gene,within
R1138	T2022	T2020	arg2Of	nucleotides,within
R1139	T2022	T2021	arg1Of	nucleotides,"50,000"
R1140	T2022	T2023	arg1Of	nucleotides,of
R1141	T2026	T2023	arg2Of	breakpoints,of
R1142	T2026	T2024	arg1Of	breakpoints,the
R1143	T2026	T2025	arg1Of	breakpoints,chromosomal
R1144	T2027	T2015	arg3Of	),(
R1145	T2029	T2028	arg2Of	14,[
R1146	T2030	T2028	arg3Of	],[
R1147	T2034	T2032	arg1Of	gene,the
R1148	T2034	T2033	arg1Of	gene,p
R1149	T2034	T2035	arg1Of	gene,functions
R1150	T2035	T2031	arg2Of	functions,Because
R1151	T2035	T2036	arg1Of	functions,solely
R1152	T2035	T2037	arg1Of	functions,in
R1153	T2038	T2037	arg2Of	pigmentation,in
R1154	T2038	T2039	arg1Of	pigmentation,[
R1155	T2040	T2039	arg2Of	16,[
R1156	T2041	T2039	arg3Of	],[
R1157	T2046	T2043	arg1Of	factor,the
R1158	T2046	T2044	arg1Of	factor,Sox6
R1159	T2046	T2045	arg1Of	factor,transcription
R1160	T2046	T2047	arg1Of	factor,is
R1161	T2046	T2048	arg2Of	factor,implicated
R1162	T2048	T2031	arg1Of	implicated,Because
R1163	T2048	T2042	arg1Of	implicated,","
R1164	T2048	T2047	arg2Of	implicated,is
R1165	T2048	T2049	arg1Of	implicated,in
R1166	T2052	T2049	arg2Of	phenotypes,in
R1167	T2052	T2050	arg1Of	phenotypes,all
R1168	T2052	T2051	arg1Of	phenotypes,other
R1169	T2057	T2053	arg2Of	proteins,Among
R1170	T2057	T2054	arg1Of	proteins,the
R1171	T2057	T2055	arg1Of	proteins,HMG
R1172	T2057	T2056	arg1Of	proteins,box
R1173	T2057	T2059	arg2Of	proteins,related
R1174	T2059	T2058	arg1Of	related,distantly
R1175	T2059	T2060	arg1Of	related,to
R1176	T2061	T2060	arg2Of	Sry,to
R1177	T2061	T2062	arg1Of	Sry,(
R1178	T2065	T2062	arg2Of	member,(
R1179	T2065	T2063	arg1Of	member,the
R1180	T2065	T2064	arg1Of	member,first
R1181	T2065	T2066	arg2Of	member,identified
R1182	T2066	T2067	arg1Of	identified,of
R1183	T2072	T2067	arg2Of	family,of
R1184	T2072	T2068	arg1Of	family,the
R1185	T2072	T2069	arg1Of	family,Sox
R1186	T2072	T2070	arg1Of	family,transcription
R1187	T2072	T2071	arg1Of	family,factor
R1188	T2073	T2062	arg3Of	),(
R1189	T2074	T2053	arg1Of	that,Among
R1190	T2074	T2076	arg1Of	that,bind
R1191	T2074	T2090	arg1Of	that,are
R1192	T2076	T2075	arg1Of	bind,similarly
R1193	T2076	T2077	arg1Of	bind,to
R1194	T2076	T2086	arg1Of	bind,without
R1195	T2077	T2085	arg1Of	to,but
R1196	T2080	T2081	arg1Of	groove,and
R1197	T2082	T2081	arg2Of	bend,and
R1198	T2083	T2077	arg2Of	DNA,to
R1199	T2083	T2078	arg1Of	DNA,the
R1200	T2083	T2079	arg1Of	DNA,minor
R1201	T2083	T2080	arg1Of	DNA,groove
R1202	T2083	T2082	arg1Of	DNA,bend
R1203	T2085	T2084	arg1Of	but,","
R1204	T2086	T2085	arg2Of	without,but
R1205	T2088	T2086	arg2Of	specificity,without
R1206	T2088	T2087	arg1Of	specificity,sequence
R1207	T2090	T2089	arg1Of	are,","
R1208	T2090	T2098	arg1Of	are,[
R1209	T2093	T2092	arg1Of	expressed,ubiquitously
R1210	T2094	T2093	arg1Of	HMG1,expressed
R1211	T2094	T2095	arg1Of	HMG1,and
R1212	T2095	T2090	arg2Of	and,are
R1213	T2095	T2091	arg1Of	and,the
R1214	T2097	T2095	arg2Of	proteins,and
R1215	T2097	T2096	arg1Of	proteins,HMG2
R1216	T2099	T2098	arg2Of	17,[
R1217	T2100	T2098	arg3Of	],[
R1218	T2101	T2102	arg1Of	Modulation,of
R1219	T2101	T2105	arg1Of	Modulation,by
R1220	T2101	T2111	arg1Of	Modulation,can
R1221	T2101	T2112	arg1Of	Modulation,mediate
R1222	T2101	T2123	arg1Of	Modulation,bringing
R1223	T2104	T2102	arg2Of	structure,of
R1224	T2104	T2103	arg1Of	structure,DNA
R1225	T2110	T2105	arg2Of	proteins,by
R1226	T2110	T2106	arg1Of	proteins,these
R1227	T2110	T2107	arg1Of	proteins,and
R1228	T2110	T2108	arg1Of	proteins,other
R1229	T2110	T2109	arg1Of	proteins,HMG
R1230	T2112	T2111	arg2Of	mediate,can
R1231	T2112	T2116	arg1Of	mediate,on
R1232	T2112	T2122	arg1Of	mediate,by
R1233	T2115	T2112	arg2Of	function,mediate
R1234	T2115	T2113	arg1Of	function,long-range
R1235	T2115	T2114	arg1Of	function,enhancer
R1236	T2118	T2119	arg1Of	DNA,and
R1237	T2119	T2116	arg2Of	and,on
R1238	T2119	T2117	arg1Of	and,both
R1239	T2121	T2119	arg2Of	genes,and
R1240	T2121	T2120	arg1Of	genes,chromatin-assembled
R1241	T2123	T2122	arg2Of	bringing,by
R1242	T2123	T2124	arg1Of	bringing,together
R1243	T2126	T2123	arg2Of	regions,bringing
R1244	T2126	T2125	arg1Of	regions,distant
R1245	T2126	T2127	arg1Of	regions,of
R1246	T2128	T2129	arg1Of	DNA,and
R1247	T2129	T2127	arg2Of	and,of
R1248	T2131	T2129	arg2Of	factors,and
R1249	T2131	T2130	arg2Of	factors,associated
R1250	T2135	T2134	arg1Of	proteins,HMG
R1251	T2135	T2136	arg1Of	proteins,have
R1252	T2135	T2137	arg1Of	proteins,been
R1253	T2135	T2138	arg2Of	proteins,shown
R1254	T2135	T2140	arg1Of	proteins,modulate
R1255	T2138	T2132	arg1Of	shown,Specifically
R1256	T2138	T2133	arg1Of	shown,","
R1257	T2138	T2136	arg2Of	shown,have
R1258	T2138	T2137	arg2Of	shown,been
R1259	T2140	T2138	arg3Of	modulate,shown
R1260	T2140	T2139	arg1Of	modulate,to
R1261	T2142	T2140	arg2Of	genes,modulate
R1262	T2142	T2141	arg1Of	genes,β-globin
R1263	T2142	T2143	arg1Of	genes,[
R1264	T2144	T2143	arg2Of	18–21,[
R1265	T2145	T2143	arg3Of	],[
R1266	T2149	T2146	arg1Of	genes,The
R1267	T2149	T2147	arg1Of	genes,mouse
R1268	T2149	T2148	arg1Of	genes,β-globin
R1269	T2149	T2150	arg1Of	genes,{
R1270	T2149	T2160	arg1Of	genes,are
R1271	T2149	T2161	arg2Of	genes,clustered
R1272	T2151	T2152	arg1Of	ɛy,","
R1273	T2151	T2154	arg1Of	ɛy,","
R1274	T2153	T2152	arg2Of	βh1,","
R1275	T2154	T2150	arg2Of	",",{
R1276	T2155	T2157	arg1Of	β-major,and
R1277	T2157	T2154	arg2Of	and,","
R1278	T2157	T2156	arg1Of	and,","
R1279	T2158	T2157	arg2Of	β-minor,and
R1280	T2159	T2150	arg3Of	},{
R1281	T2161	T2160	arg2Of	clustered,are
R1282	T2161	T2162	arg1Of	clustered,on
R1283	T2161	T2165	arg1Of	clustered,and
R1284	T2163	T2162	arg2Of	Chromosome,on
R1285	T2163	T2164	arg1Of	Chromosome,7
R1286	T2166	T2167	arg1Of	they,are
R1287	T2166	T2169	arg1Of	they,homologous
R1288	T2167	T2165	arg2Of	are,and
R1289	T2167	T2174	arg1Of	are,in
R1290	T2167	T2179	arg1Of	are,[
R1291	T2169	T2167	arg2Of	homologous,are
R1292	T2169	T2168	arg1Of	homologous,highly
R1293	T2169	T2170	arg1Of	homologous,to
R1294	T2173	T2170	arg2Of	counterparts,to
R1295	T2173	T2171	arg1Of	counterparts,their
R1296	T2173	T2172	arg1Of	counterparts,human
R1297	T2176	T2177	arg1Of	structure,and
R1298	T2177	T2174	arg2Of	and,in
R1299	T2177	T2175	arg1Of	and,organizational
R1300	T2178	T2177	arg2Of	function,and
R1301	T2180	T2179	arg2Of	22,[
R1302	T2181	T2179	arg3Of	],[
R1303	T2183	T2182	arg1Of	expression,High-level
R1304	T2183	T2184	arg1Of	expression,of
R1305	T2183	T2187	arg1Of	expression,requires
R1306	T2186	T2184	arg2Of	genes,of
R1307	T2186	T2185	arg1Of	genes,these
R1308	T2190	T2187	arg2Of	element,requires
R1309	T2190	T2188	arg1Of	element,a
R1310	T2190	T2189	arg1Of	element,regulatory
R1311	T2190	T2191	arg1Of	element,","
R1312	T2270	T2268	arg1Of	cells,definitive
R1313	T2270	T2269	arg1Of	cells,erythroid
R1314	T2270	T2271	arg1Of	cells,express
R1315	T2195	T2191	arg2Of	region,","
R1316	T2271	T2267	arg2Of	express,where
R1317	T2274	T2271	arg2Of	globins,express
R1318	T2274	T2272	arg1Of	globins,adult
R1319	T2274	T2273	arg1Of	globins,β
R1320	T2276	T2252	arg1Of	β,At
R1321	T2276	T2260	arg1Of	β,","
R1322	T2276	T2275	arg1Of	β,(
R1323	T2277	T2278	arg1Of	major,and
R1324	T2195	T2192	arg1Of	region,the
R1325	T2195	T2193	arg1Of	region,locus
R1326	T2279	T2278	arg2Of	minor,and
R1327	T2195	T2194	arg1Of	region,control
R1328	T2195	T2196	arg1Of	region,that
R1329	T2195	T2197	arg1Of	region,is
R1330	T2282	T2276	arg2Of	22,β
R1331	T2282	T2277	arg1Of	22,major
R1332	T2282	T2279	arg1Of	22,minor
R1333	T2282	T2280	arg1Of	22,)
R1334	T2282	T2281	arg2Of	22,[
R1335	T2283	T2281	arg3Of	],[
R1336	T2195	T2198	arg2Of	region,characterized
R1337	T2198	T2197	arg2Of	characterized,is
R1338	T2286	T2284	arg1Of	gene,The
R1339	T2286	T2285	arg1Of	gene,ɛy
R1340	T2286	T2287	arg1Of	gene,is
R1341	T2286	T2288	arg2Of	gene,silenced
R1342	T2288	T2287	arg2Of	silenced,is
R1343	T2288	T2289	arg1Of	silenced,in
R1344	T2201	T2198	arg1Of	set,characterized
R1345	T2292	T2289	arg2Of	cells,in
R1346	T2292	T2290	arg1Of	cells,definitive
R1347	T2292	T2291	arg1Of	cells,erythroid
R1348	T2294	T2293	arg1Of	mechanism,The
R1349	T2201	T2199	arg2Of	set,by
R1350	T2201	T2200	arg1Of	set,a
R1351	T2294	T2295	arg1Of	mechanism,of
R1352	T2294	T2305	arg1Of	mechanism,has
R1353	T2294	T2306	arg1Of	mechanism,been
R1354	T2294	T2307	arg2Of	mechanism,studied
R1355	T2296	T2295	arg2Of	silencing,of
R1356	T2296	T2297	arg1Of	silencing,of
R1357	T2300	T2297	arg2Of	counterpart,of
R1358	T2300	T2298	arg1Of	counterpart,its
R1359	T2300	T2299	arg1Of	counterpart,human
R1360	T2300	T2301	arg1Of	counterpart,","
R1361	T2201	T2202	arg1Of	set,of
R1362	T2205	T2202	arg2Of	sites,of
R1363	T2303	T2301	arg2Of	globin,","
R1364	T2303	T2302	arg1Of	globin,ɛ
R1365	T2307	T2304	arg1Of	studied,","
R1366	T2307	T2305	arg2Of	studied,has
R1367	T2307	T2306	arg2Of	studied,been
R1368	T2307	T2308	arg1Of	studied,extensively
R1369	T2205	T2203	arg1Of	sites,nuclease
R1370	T2311	T2309	arg2Of	erythropoiesis,In
R1371	T2311	T2310	arg1Of	erythropoiesis,definitive
R1372	T2205	T2204	arg1Of	sites,hypersensitive
R1373	T2205	T2206	arg2Of	sites,spread
R1374	T2313	T2314	arg1Of	ɛ,is
R1375	T2313	T2315	arg2Of	ɛ,activated
R1376	T2313	T2317	arg2Of	ɛ,silenced
R1377	T2206	T2207	arg1Of	spread,over
R1378	T2315	T2316	arg1Of	activated,and
R1379	T2316	T2309	arg1Of	and,In
R1380	T2316	T2312	arg1Of	and,","
R1381	T2316	T2314	arg2Of	and,is
R1382	T2316	T2319	arg1Of	and,[
R1383	T2316	T2322	arg1Of	and,","
R1384	T2316	T2323	arg1Of	and,although
R1385	T2317	T2316	arg2Of	silenced,and
R1386	T2317	T2318	arg1Of	silenced,autonomously
R1387	T2206	T2216	arg1Of	spread,[
R1388	T2320	T2319	arg2Of	"24,25",[
R1389	T2211	T2207	arg2Of	5′,over
R1390	T2321	T2319	arg3Of	],[
R1391	T2326	T2324	arg2Of	erythropoiesis,in
R1392	T2326	T2325	arg1Of	erythropoiesis,primitive
R1393	T2327	T2329	arg1Of	ɛ,appears
R1394	T2327	T2331	arg1Of	ɛ,be
R1395	T2211	T2208	arg1Of	5′,25
R1396	T2327	T2332	arg2Of	ɛ,regulated
R1397	T2211	T2209	arg1Of	5′,kb
R1398	T2329	T2323	arg2Of	appears,although
R1399	T2329	T2324	arg1Of	appears,in
R1400	T2329	T2328	arg1Of	appears,also
R1401	T2211	T2210	arg1Of	5′,located
R1402	T2211	T2212	arg1Of	5′,of
R1403	T2332	T2329	arg2Of	regulated,appears
R1404	T2332	T2330	arg1Of	regulated,to
R1405	T2332	T2331	arg2Of	regulated,be
R1406	T2332	T2333	arg1Of	regulated,competitively
R1407	T2332	T2334	arg1Of	regulated,[
R1408	T2335	T2334	arg2Of	26,[
R1409	T2336	T2334	arg3Of	],[
R1410	T2215	T2212	arg2Of	gene,of
R1411	T2338	T2337	arg1Of	γ-globin,The
R1412	T2338	T2339	arg1Of	γ-globin,to
R1413	T2338	T2343	arg1Of	γ-globin,is
R1414	T2338	T2344	arg2Of	γ-globin,controlled
R1415	T2342	T2339	arg2Of	switch,to
R1416	T2342	T2340	arg1Of	switch,adult
R1417	T2342	T2341	arg1Of	switch,β-globin
R1418	T2344	T2343	arg2Of	controlled,is
R1419	T2344	T2351	arg1Of	controlled,[
R1420	T2215	T2213	arg1Of	gene,the
R1421	T2215	T2214	arg1Of	gene,ɛy
R1422	T2347	T2344	arg1Of	competition,controlled
R1423	T2347	T2345	arg2Of	competition,by
R1424	T2347	T2346	arg1Of	competition,promoter
R1425	T2347	T2348	arg1Of	competition,for
R1426	T2217	T2216	arg2Of	23,[
R1427	T2350	T2348	arg2Of	LCR,for
R1428	T2350	T2349	arg1Of	LCR,the
R1429	T2352	T2351	arg2Of	"24,25",[
R1430	T2218	T2216	arg3Of	],[
R1431	T2353	T2351	arg3Of	],[
R1432	T2221	T2219	arg1Of	genes,The
R1433	T2356	T2354	arg1Of	elements,All
R1434	T2356	T2355	arg1Of	elements,the
R1435	T2356	T2357	arg1Of	elements,responsible
R1436	T2356	T2364	arg1Of	elements,are
R1437	T2356	T2365	arg1Of	elements,within
R1438	T2356	T2370	arg1Of	elements,in
R1439	T2357	T2358	arg1Of	responsible,for
R1440	T2221	T2220	arg1Of	genes,β-globin
R1441	T2359	T2358	arg2Of	silencing,for
R1442	T2221	T2222	arg1Of	genes,are
R1443	T2221	T2223	arg2Of	genes,expressed
R1444	T2223	T2222	arg2Of	expressed,are
R1445	T2363	T2359	arg2Of	gene,silencing
R1446	T2363	T2360	arg1Of	gene,the
R1447	T2363	T2361	arg1Of	gene,ɛ
R1448	T2363	T2362	arg1Of	gene,globin
R1449	T2364	T2376	arg1Of	are,","
R1450	T2364	T2377	modOf	are,suggesting
R1451	T2365	T2369	arg1Of	within,or
R1452	T2223	T2224	arg1Of	expressed,in
R1453	T2226	T2227	arg1Of	tissue-,and
R1454	T2228	T2227	arg2Of	development-specific,and
R1455	T2368	T2365	arg2Of	gene,within
R1456	T2368	T2366	arg1Of	gene,the
R1457	T2368	T2367	arg1Of	gene,ɛ
R1458	T2369	T2364	arg2Of	or,are
R1459	T2370	T2369	arg2Of	in,or
R1460	T2229	T2224	arg2Of	fashion,in
R1461	T2372	T2370	arg2Of	sequences,in
R1462	T2372	T2371	arg1Of	sequences,adjacent
R1463	T2372	T2373	arg1Of	sequences,[
R1464	T2229	T2225	arg1Of	fashion,a
R1465	T2374	T2373	arg2Of	27,[
R1466	T2375	T2373	arg3Of	],[
R1467	T2229	T2226	arg1Of	fashion,tissue-
R1468	T2229	T2228	arg1Of	fashion,development-specific
R1469	T2231	T2230	arg2Of	mice,In
R1470	T2379	T2380	arg1Of	silencing,is
R1471	T2379	T2383	arg1Of	silencing,autonomous
R1472	T2380	T2377	arg2Of	is,suggesting
R1473	T2380	T2378	arg1Of	is,that
R1474	T2380	T2381	arg1Of	is,primarily
R1475	T2233	T2234	arg1Of	erythropoiesis,originates
R1476	T2383	T2380	arg2Of	autonomous,is
R1477	T2234	T2230	arg1Of	originates,In
R1478	T2383	T2382	arg1Of	autonomous,gene
R1479	T2234	T2232	arg1Of	originates,","
R1480	T2234	T2235	arg1Of	originates,in
R1481	T2239	T2235	arg2Of	sac,in
R1482	T2387	T2384	arg2Of	analyses,Using
R1483	T2387	T2385	arg1Of	analyses,promoter
R1484	T2387	T2386	arg1Of	analyses,deletion
R1485	T2387	T2388	arg1Of	analyses,in
R1486	T2391	T2389	arg1Of	models,transgenic
R1487	T2391	T2390	arg1Of	models,mouse
R1488	T2391	T2392	arg1Of	models,and
R1489	T2392	T2388	arg2Of	and,in
R1490	T2239	T2236	arg1Of	sac,the
R1491	T2395	T2392	arg2Of	assays,and
R1492	T2395	T2393	arg1Of	assays,cell
R1493	T2395	T2394	arg1Of	assays,transfection
R1494	T2239	T2237	arg1Of	sac,embryonic
R1495	T2239	T2238	arg1Of	sac,yolk
R1496	T2239	T2240	arg1Of	sac,where
R1497	T2399	T2384	arg1Of	elements,Using
R1498	T2399	T2397	arg1Of	elements,multiple
R1499	T2399	T2398	arg1Of	elements,DNA
R1500	T2399	T2400	arg1Of	elements,important
R1501	T2399	T2405	arg1Of	elements,have
R1502	T2399	T2406	arg1Of	elements,been
R1503	T2399	T2408	arg2Of	elements,identified
R1504	T2400	T2401	arg1Of	important,to
R1505	T2243	T2241	arg1Of	cells,primitive
R1506	T2404	T2401	arg2Of	process,to
R1507	T2404	T2402	arg1Of	process,the
R1508	T2404	T2403	arg1Of	process,silencing
R1509	T2408	T2384	modOf	identified,Using
R1510	T2408	T2396	arg1Of	identified,","
R1511	T2408	T2405	arg2Of	identified,have
R1512	T2408	T2406	arg2Of	identified,been
R1513	T2408	T2407	arg1Of	identified,previously
R1514	T2408	T2409	arg1Of	identified,in
R1515	T2408	T2419	arg1Of	identified,[
R1516	T2412	T2413	arg1Of	proximal,and
R1517	T2243	T2242	arg1Of	cells,erythroid
R1518	T2243	T2244	arg1Of	cells,express
R1519	T2244	T2240	arg2Of	express,where
R1520	T2415	T2413	arg2Of	distal,and
R1521	T2415	T2414	arg1Of	distal,the
R1522	T2244	T2249	arg1Of	express,[
R1523	T2418	T2409	arg2Of	promoter,in
R1524	T2418	T2410	arg1Of	promoter,both
R1525	T2418	T2411	arg1Of	promoter,the
R1526	T2418	T2412	arg1Of	promoter,proximal
R1527	T2418	T2415	arg1Of	promoter,distal
R1528	T2418	T2416	arg1Of	promoter,ɛ
R1529	T2418	T2417	arg1Of	promoter,gene
R1530	T2420	T2419	arg2Of	27,[
R1531	T2245	T2246	arg1Of	ɛy,and
R1532	T2421	T2419	arg3Of	],[
R1533	T2247	T2246	arg2Of	βh-1,and
R1534	T2425	T2422	arg1Of	factors,Their
R1535	T2425	T2423	arg1Of	factors,corresponding
R1536	T2425	T2424	arg1Of	factors,transcription
R1537	T2425	T2426	arg1Of	factors,","
R1538	T2425	T2428	arg1Of	factors,as
R1539	T2248	T2244	arg2Of	globins,express
R1540	T2425	T2437	arg1Of	factors,have
R1541	T2425	T2438	arg1Of	factors,been
R1542	T2425	T2439	arg2Of	factors,identified
R1543	T2425	T2441	arg2Of	factors,shown
R1544	T2425	T2444	arg1Of	factors,bind
R1545	T2425	T2457	arg1Of	factors,regulate
R1546	T2248	T2245	arg1Of	globins,ɛy
R1547	T2248	T2247	arg1Of	globins,βh-1
R1548	T2428	T2427	arg1Of	as,such
R1549	T2250	T2249	arg2Of	22,[
R1550	T2429	T2430	arg1Of	GATA-1,","
R1551	T2430	T2432	arg1Of	",",","
R1552	T2431	T2430	arg2Of	YY-1,","
R1553	T2432	T2435	arg1Of	",",and
R1554	T2251	T2249	arg3Of	],[
R1555	T2433	T2432	arg2Of	COUP-TF,","
R1556	T2435	T2428	arg2Of	and,as
R1557	T2435	T2434	arg1Of	and,","
R1558	T2436	T2435	arg2Of	DRED,and
R1559	T2256	T2252	arg2Of	coitus,At
R1560	T2439	T2440	arg1Of	identified,and
R1561	T2440	T2437	arg2Of	and,have
R1562	T2440	T2438	arg2Of	and,been
R1563	T2441	T2440	arg2Of	shown,and
R1564	T2444	T2441	arg3Of	bind,shown
R1565	T2444	T2442	arg1Of	bind,to
R1566	T2444	T2443	arg1Of	bind,directly
R1567	T2444	T2445	arg1Of	bind,to
R1568	T2444	T2449	arg1Of	bind,(
R1569	T2444	T2456	modOf	bind,to
R1570	T2444	T2459	modOf	bind,silencing
R1571	T2444	T2460	arg1Of	bind,[
R1572	T2256	T2253	arg1Of	coitus,11.5
R1573	T2448	T2445	arg2Of	elements,to
R1574	T2448	T2446	arg1Of	elements,these
R1575	T2448	T2447	arg1Of	elements,DNA
R1576	T2256	T2254	arg1Of	coitus,d
R1577	T2450	T2449	arg2Of	as,(
R1578	T2256	T2255	arg1Of	coitus,post
R1579	T2451	T2450	arg2Of	part,as
R1580	T2451	T2452	arg1Of	part,of
R1581	T2256	T2257	arg1Of	coitus,(
R1582	T2258	T2257	arg2Of	dpc,(
R1583	T2454	T2452	arg2Of	complexes,of
R1584	T2454	T2453	arg1Of	complexes,protein
R1585	T2455	T2449	arg3Of	),(
R1586	T2457	T2456	arg1Of	regulate,to
R1587	T2457	T2458	arg1Of	regulate,ɛ
R1588	T2259	T2257	arg3Of	),(
R1589	T2262	T2261	arg1Of	shifts,erythropoiesis
R1590	T2461	T2460	arg2Of	27,[
R1591	T2462	T2460	arg3Of	],[
R1592	T2262	T2263	arg1Of	shifts,to
R1593	T2262	T2267	arg1Of	shifts,where
R1594	T2262	T2276	arg1Of	shifts,β
R1595	T2266	T2263	arg2Of	liver,to
R1596	T2266	T2264	arg1Of	liver,the
R1597	T2266	T2265	arg1Of	liver,fetal
R1598	T2465	T2466	arg1Of	it,appears
R1599	T2561	T2560	arg2Of	maturation,delayed
R1600	T2466	T2463	arg1Of	appears,Thus
R1601	T2466	T2464	arg1Of	appears,","
R1602	T2469	T2468	arg1Of	silencing,the
R1603	T2469	T2470	arg1Of	silencing,of
R1604	T2469	T2474	arg1Of	silencing,involves
R1605	T2473	T2470	arg2Of	gene,of
R1606	T2473	T2471	arg1Of	gene,the
R1607	T2473	T2472	arg1Of	gene,ɛ
R1608	T2474	T2466	arg2Of	involves,appears
R1609	T2474	T2467	arg1Of	involves,that
R1610	T2477	T2474	arg2Of	network,involves
R1611	T2477	T2475	arg1Of	network,a
R1612	T2477	T2476	arg1Of	network,complicated
R1613	T2477	T2478	arg1Of	network,of
R1614	T2561	T2562	arg1Of	maturation,of
R1615	T2561	T2564	arg1Of	maturation,(
R1616	T2561	T2577	arg1Of	maturation,and
R1617	T2481	T2479	arg1Of	elements,multiple
R1618	T2481	T2480	arg1Of	elements,cis
R1619	T2481	T2482	arg1Of	elements,and
R1620	T2563	T2562	arg2Of	erythrocytes,of
R1621	T2482	T2478	arg2Of	and,of
R1622	T2484	T2482	arg2Of	proteins,and
R1623	T2484	T2483	arg1Of	proteins,transacting
R1624	T2486	T2487	arg1Of	addition,to
R1625	T2565	T2564	arg2Of	that,(
R1626	T2486	T2503	arg1Of	addition,","
R1627	T2565	T2567	arg1Of	that,enucleate
R1628	T2488	T2487	arg2Of	playing,to
R1629	T2488	T2492	arg1Of	playing,in
R1630	T2567	T2566	arg1Of	enucleate,normally
R1631	T2491	T2488	arg2Of	role,playing
R1632	T2491	T2489	arg1Of	role,an
R1633	T2491	T2490	arg1Of	role,important
R1634	T2567	T2569	arg1Of	enucleate,to
R1635	T2494	T2492	arg2Of	development,in
R1636	T2494	T2493	arg1Of	development,the
R1637	T2494	T2495	arg1Of	development,of
R1638	T2569	T2568	arg1Of	to,prior
R1639	T2570	T2569	arg2Of	entering,to
R1640	T2499	T2495	arg2Of	system,of
R1641	T2499	T2496	arg1Of	system,the
R1642	T2499	T2497	arg1Of	system,central
R1643	T2499	T2498	arg1Of	system,nervous
R1644	T2499	T2500	arg1Of	system,[
R1645	T2501	T2500	arg2Of	8–11,[
R1646	T2572	T2570	arg2Of	bloodstream,entering
R1647	T2502	T2500	arg3Of	],[
R1648	T2503	T2509	arg1Of	",",and
R1649	T2504	T2503	arg2Of	cartilage,","
R1650	T2504	T2505	arg1Of	cartilage,[
R1651	T2572	T2571	arg1Of	bloodstream,the
R1652	T2506	T2505	arg2Of	"6,12,13",[
R1653	T2507	T2505	arg3Of	],[
R1654	T2572	T2573	arg1Of	bloodstream,[
R1655	T2574	T2573	arg2Of	27,[
R1656	T2509	T2485	arg2Of	and,In
R1657	T2509	T2508	arg1Of	and,","
R1658	T2510	T2509	arg2Of	muscle,and
R1659	T2510	T2511	arg1Of	muscle,[
R1660	T2512	T2511	arg2Of	"14,15",[
R1661	T2513	T2511	arg3Of	],[
R1662	T2515	T2516	arg1Of	it,was
R1663	T2515	T2517	arg2Of	it,shown
R1664	T2575	T2573	arg3Of	],[
R1665	T2517	T2485	arg1Of	shown,In
R1666	T2517	T2514	arg1Of	shown,","
R1667	T2517	T2516	arg2Of	shown,was
R1668	T2519	T2520	arg1Of	Sox6,is
R1669	T2519	T2521	arg2Of	Sox6,upregulated
R1670	T2576	T2564	arg3Of	),(
R1671	T2521	T2517	arg3Of	upregulated,shown
R1672	T2521	T2518	arg1Of	upregulated,that
R1673	T2521	T2520	arg2Of	upregulated,is
R1674	T2521	T2522	arg1Of	upregulated,in
R1675	T2521	T2530	arg1Of	upregulated,compared
R1676	T2521	T2540	arg1Of	upregulated,[
R1677	T2577	T2559	arg2Of	and,include
R1678	T2526	T2522	arg2Of	cells,in
R1679	T2526	T2523	arg1Of	cells,long-term
R1680	T2526	T2524	arg1Of	cells,hematopoiesis
R1681	T2526	T2525	arg1Of	cells,stem
R1682	T2526	T2527	arg1Of	cells,(
R1683	T2528	T2527	arg2Of	LT-HSC,(
R1684	T2579	T2577	arg2Of	expression,and
R1685	T2529	T2527	arg3Of	),(
R1686	T2531	T2530	arg2Of	with,compared
R1687	T2579	T2578	arg1Of	expression,higher
R1688	T2579	T2580	arg1Of	expression,of
R1689	T2533	T2531	arg2Of	progenitors,with
R1690	T2533	T2532	arg1Of	progenitors,multipotent
R1691	T2533	T2534	arg1Of	progenitors,of
R1692	T2583	T2580	arg2Of	genes,of
R1693	T2539	T2534	arg2Of	lineage,of
R1694	T2539	T2535	arg1Of	lineage,adult
R1695	T2539	T2536	arg1Of	lineage,mouse
R1696	T2539	T2537	arg1Of	lineage,bone
R1697	T2539	T2538	arg1Of	lineage,marrow
R1698	T2583	T2581	arg1Of	genes,embryonic
R1699	T2541	T2540	arg2Of	28,[
R1700	T2542	T2540	arg3Of	],[
R1701	T2583	T2582	arg1Of	genes,globin
R1702	T2586	T2585	arg1Of	extreme,most
R1703	T2545	T2543	arg2Of	study,In
R1704	T2545	T2544	arg1Of	study,this
R1705	T2547	T2548	arg2Of	we,describe
R1706	T2548	T2543	arg1Of	describe,In
R1707	T2548	T2546	arg1Of	describe,","
R1708	T2550	T2552	arg1Of	Sox6,exerts
R1709	T2587	T2584	arg1Of	effect,The
R1710	T2552	T2548	arg1Of	exerts,describe
R1711	T2552	T2549	arg1Of	exerts,that
R1712	T2552	T2551	arg1Of	exerts,also
R1713	T2552	T2555	arg1Of	exerts,on
R1714	T2554	T2552	arg2Of	effects,exerts
R1715	T2554	T2553	arg1Of	effects,pleiotropic
R1716	T2556	T2555	arg2Of	erythropoiesis,on
R1717	T2587	T2586	arg1Of	effect,extreme
R1718	T2587	T2588	arg1Of	effect,is
R1719	T2558	T2557	arg1Of	effects,These
R1720	T2558	T2559	arg1Of	effects,include
R1721	T2590	T2588	arg2Of	persistence,is
R1722	T2590	T2589	arg1Of	persistence,the
R1723	T2590	T2591	arg1Of	persistence,of
R1724	T2593	T2591	arg2Of	expression,of
R1725	T2657	T2653	arg2Of	pattern,","
R1726	T2657	T2654	arg1Of	pattern,the
R1727	T2657	T2655	arg1Of	pattern,opposite
R1728	T2657	T2656	arg1Of	pattern,expression
R1729	T2657	T2658	arg1Of	pattern,of
R1730	T2660	T2658	arg2Of	globin,of
R1731	T2660	T2659	arg1Of	globin,ɛy
R1732	T2593	T2592	arg1Of	expression,high
R1733	T2661	T2662	arg1Of	In,the
R1734	T2661	T2664	arg1Of	In,of
R1735	T2593	T2594	arg1Of	expression,of
R1736	T2663	T2661	arg2Of	absence,In
R1737	T2599	T2594	arg2Of	gene,of
R1738	T2665	T2661	arg3Of	Sox6,In
R1739	T2668	T2667	arg1Of	globin,ɛy
R1740	T2668	T2669	arg1Of	globin,is
R1741	T2668	T2671	arg2Of	globin,expressed
R1742	T2671	T2661	arg1Of	expressed,In
R1743	T2599	T2595	arg1Of	gene,the
R1744	T2671	T2666	arg1Of	expressed,","
R1745	T2671	T2669	arg2Of	expressed,is
R1746	T2671	T2670	arg1Of	expressed,ectopically
R1747	T2671	T2672	arg1Of	expressed,in
R1748	T2671	T2676	arg1Of	expressed,","
R1749	T2671	T2677	modOf	expressed,demonstrating
R1750	T2599	T2596	arg1Of	gene,embryonic
R1751	T2599	T2597	arg1Of	gene,ɛy
R1752	T2675	T2672	arg2Of	liver,in
R1753	T2675	T2673	arg1Of	liver,the
R1754	T2675	T2674	arg1Of	liver,fetal
R1755	T2599	T2598	arg1Of	gene,globin
R1756	T2601	T2602	arg1Of	we,describe
R1757	T2680	T2677	arg2Of	functions,demonstrating
R1758	T2680	T2678	arg1Of	functions,that
R1759	T2680	T2679	arg1Of	functions,Sox6
R1760	T2680	T2681	arg1Of	functions,in
R1761	T2683	T2681	arg2Of	erythropoiesis,in
R1762	T2683	T2682	arg1Of	erythropoiesis,definitive
R1763	T2601	T2604	arg1Of	we,characterize
R1764	T2602	T2603	arg1Of	describe,and
R1765	T2603	T2600	arg1Of	and,Here
R1766	T2604	T2603	arg2Of	characterize,and
R1767	T2606	T2602	arg2Of	effects,describe
R1768	T2606	T2604	arg2Of	effects,characterize
R1769	T2606	T2605	arg1Of	effects,the
R1770	T2606	T2607	arg1Of	effects,of
R1771	T2606	T2609	arg1Of	effects,on
R1772	T2608	T2607	arg2Of	Sox6,of
R1773	T2613	T2609	arg2Of	gene,on
R1776	T2613	T2610	arg1Of	gene,the
R1777	T2613	T2611	arg1Of	gene,ɛy
R1778	T2613	T2612	arg1Of	gene,globin
R1779	T2614	T2615	arg1Of	We,show
R1781	T2617	T2618	arg1Of	Sox6,binds
R1783	T2617	T2627	arg1Of	Sox6,represses
R1784	T2618	T2619	arg1Of	binds,to
R1785	T2618	T2626	arg1Of	binds,and
R1787	T2622	T2619	arg2Of	promoter,to
R1789	T2622	T2620	arg1Of	promoter,the
R1790	T2622	T2621	arg1Of	promoter,proximal
R1791	T2622	T2623	arg1Of	promoter,of
R1792	T2625	T2623	arg2Of	globin,of
R1795	T2625	T2624	arg1Of	globin,ɛy
R1796	T2626	T2615	arg2Of	and,show
R1797	T2626	T2616	arg1Of	and,that
R1798	T2627	T2626	arg2Of	represses,and
R1799	T2629	T2627	arg2Of	transcription,represses
R1800	T2629	T2628	arg1Of	transcription,its
R1801	T2631	T2632	arg1Of	wild-type,(
R1803	T2633	T2632	arg2Of	WT,(
R1804	T2634	T2632	arg3Of	),(
R1806	T2635	T2630	arg2Of	mice,In
R1807	T2635	T2631	arg1Of	mice,wild-type
R1810	T2637	T2638	arg1Of	Sox6,is
R1812	T2637	T2640	arg2Of	Sox6,expressed
R1813	T2637	T2648	arg1Of	Sox6,is
R1814	T2637	T2649	arg2Of	Sox6,expressed
R1815	T2640	T2638	arg2Of	expressed,is
R1817	T2640	T2639	arg1Of	expressed,not
R1818	T2640	T2641	arg1Of	expressed,in
R1819	T2640	T2647	arg1Of	expressed,but
R1821	T2645	T2641	arg2Of	islands,in
R1823	T2645	T2642	arg1Of	islands,yolk
R1824	T2645	T2643	arg1Of	islands,sac
R1825	T2645	T2644	arg1Of	islands,blood
R1827	T2647	T2630	arg1Of	but,In
R1829	T2647	T2636	arg1Of	but,","
R1830	T2647	T2646	arg1Of	but,","
R1831	T2649	T2647	arg2Of	expressed,but
R1833	T2649	T2648	arg2Of	expressed,is
R1834	T2649	T2650	arg1Of	expressed,in
R1835	T2652	T2650	arg2Of	liver,in
R1838	T2652	T2651	arg1Of	liver,fetal
R1839	T2652	T2653	arg1Of	liver,","
R803	T1699	T1696	arg1Of	box,Sry
R804	T1699	T1697	arg1Of	box,type
R805	T1699	T1698	arg1Of	box,HMG
R806	T1699	T1700	arg1Of	box,(
R807	T1699	T1703	arg1Of	box,is
R808	T1701	T1700	arg2Of	Sox6,(
R809	T1702	T1700	arg3Of	),(
R810	T1705	T1703	arg2Of	member,is

bionlp-st-ge-2016-coref

Id	Subject	Object	Predicate	Lexical cue
T1410	3287-3296	Anaphor	denotes	β globins
T1409	2611-2618	Antecedent	denotes	β-minor
T1408	2598-2605	Antecedent	denotes	β-major
T1407	2593-2596	Antecedent	denotes	βh1
T1406	2589-2591	Antecedent	denotes	ɛy
T1405	2781-2792	Anaphor	denotes	these genes
T1414	5275-5284	Antecedent	denotes	ɛy globin
T1413	5299-5302	Anaphor	denotes	its
T1412	3298-3305	Antecedent	denotes	β major
T1411	3310-3315	Antecedent	denotes	minor
R746	T1405	T1406	boundBy	these genes,ɛy
R747	T1405	T1407	boundBy	these genes,βh1
R748	T1405	T1408	boundBy	these genes,β-major
R749	T1405	T1409	boundBy	these genes,β-minor
R750	T1410	T1411	boundBy	β globins,minor
R751	T1410	T1412	boundBy	β globins,β major
R752	T1413	T1414	boundBy	its,ɛy globin

bionlp-st-ge-2016-test-proteins

Id	Subject	Object	Predicate	Lexical cue
T1468	5568-5572	Protein	denotes	Sox6
T1467	5494-5503	Protein	denotes	ɛy globin
T1466	5488-5492	Protein	denotes	Sox6
T1465	5459-5468	Protein	denotes	ɛy globin
T1464	5342-5346	Protein	denotes	Sox6
T1463	5275-5284	Protein	denotes	ɛy globin
T1462	5236-5240	Protein	denotes	Sox6
T1461	5207-5216	Protein	denotes	ɛy globin
T1460	5195-5199	Protein	denotes	Sox6
T1459	5130-5139	Protein	denotes	ɛy globin
T1458	4824-4828	Protein	denotes	Sox6
T1457	4646-4650	Protein	denotes	Sox6
T1456	4400-4401	Protein	denotes	ɛ
T1455	4339-4340	Protein	denotes	ɛ
T1454	4221-4225	Protein	denotes	DRED
T1453	4208-4215	Protein	denotes	COUP-TF
T1452	4202-4206	Protein	denotes	YY-1
T1451	4194-4200	Protein	denotes	GATA-1
T1450	4121-4122	Protein	denotes	ɛ
T1449	3812-3813	Protein	denotes	ɛ
T1448	3783-3791	Protein	denotes	ɛ globin
T1447	3661-3669	Protein	denotes	β-globin
T1446	3643-3651	Protein	denotes	γ-globin
T1445	3588-3589	Protein	denotes	ɛ
T1444	3501-3502	Protein	denotes	ɛ
T1443	3431-3439	Protein	denotes	ɛ globin
T1442	3327-3329	Protein	denotes	ɛy
T1441	3310-3315	Protein	denotes	minor
T1440	3298-3305	Protein	denotes	β major
T1439	3151-3163	Protein	denotes	βh-1 globins
T1438	3144-3146	Protein	denotes	ɛy
T1437	2949-2951	Protein	denotes	ɛy
T1436	2611-2618	Protein	denotes	β-minor
T1435	2598-2605	Protein	denotes	β-major
T1434	2593-2596	Protein	denotes	βh1
T1433	2589-2591	Protein	denotes	ɛy
T1432	2253-2257	Protein	denotes	HMG2
T1431	2244-2248	Protein	denotes	HMG1
T1430	2052-2055	Protein	denotes	Sry
T1429	1939-1943	Protein	denotes	Sox6
T1428	1889-1890	Protein	denotes	p
T1427	1784-1788	Protein	denotes	Sox6
T1426	1769-1770	Protein	denotes	p
T1425	1454-1458	Protein	denotes	Sox6
T1424	1295-1299	Protein	denotes	Sox6
T1423	1209-1213	Protein	denotes	Sox6
T1422	1099-1102	Protein	denotes	Sry
T1421	1090-1094	Protein	denotes	Sox9
T1420	1084-1088	Protein	denotes	Sox6
T1419	973-977	Protein	denotes	Sox6
T1418	855-859	Protein	denotes	Sox6
T1417	693-697	Protein	denotes	Sox6
T1416	31-35	Protein	denotes	Sox6
T1415	13-16	Protein	denotes	Sry

UBERON-AE

Id	Subject	Object	Predicate	Lexical cue
T1199	1627-1632	http://purl.obolibrary.org/obo/UBERON_0000948	denotes	heart
T1198	1388-1402	http://purl.obolibrary.org/obo/UBERON_0001016	denotes	nervous system
T1197	1380-1402	http://purl.obolibrary.org/obo/UBERON_0001017	denotes	central nervous system
T1196	1380-1387	http://purl.obolibrary.org/obo/UBERON_0012131	denotes	central

GO-BP

Id	Subject	Object	Predicate	Lexical cue
T1290	4910-4936	http://purl.obolibrary.org/obo/GO_0043249	denotes	maturation of erythrocytes
T1289	4679-4692	http://purl.obolibrary.org/obo/GO_0030097	denotes	hematopoiesis
T1288	3563-3587	http://purl.obolibrary.org/obo/GO_0060319	denotes	primitive erythropoiesis
T1287	5586-5611	http://purl.obolibrary.org/obo/GO_0060318	denotes	definitive erythropoiesis
T1286	3474-3499	http://purl.obolibrary.org/obo/GO_0060318	denotes	definitive erythropoiesis
T1285	3330-3346	http://purl.obolibrary.org/obo/GO_0016458	denotes	gene is silenced
T1284	5597-5611	http://purl.obolibrary.org/obo/GO_0030218	denotes	erythropoiesis
T1283	4864-4878	http://purl.obolibrary.org/obo/GO_0030218	denotes	erythropoiesis
T1282	3573-3587	http://purl.obolibrary.org/obo/GO_0030218	denotes	erythropoiesis
T1281	3485-3499	http://purl.obolibrary.org/obo/GO_0030218	denotes	erythropoiesis
T1280	3199-3213	http://purl.obolibrary.org/obo/GO_0030218	denotes	erythropoiesis
T1279	3052-3066	http://purl.obolibrary.org/obo/GO_0030218	denotes	erythropoiesis
T1278	3001-3024	http://purl.obolibrary.org/obo/GO_0009888	denotes	tissue- and development
T1277	2892-2906	http://purl.obolibrary.org/obo/GO_0002524	denotes	hypersensitive
T1276	5497-5503	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1275	5462-5468	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1274	5278-5284	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1273	5210-5216	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1272	5133-5139	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1271	5037-5043	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1270	3785-3791	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1269	3663-3669	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1268	3645-3651	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1267	3433-3439	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1266	2969-2975	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1265	2575-2581	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1264	2541-2547	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1263	1916-1928	http://purl.obolibrary.org/obo/GO_0043473	denotes	pigmentation
T1262	1579-1585	http://purl.obolibrary.org/obo/GO_0040007	denotes	growth
T1261	4537-4578	http://purl.obolibrary.org/obo/GO_0021954	denotes	development of the central nervous system
T1260	1361-1402	http://purl.obolibrary.org/obo/GO_0021954	denotes	development of the central nervous system
T1259	4537-4578	http://purl.obolibrary.org/obo/GO_0007417	denotes	development of the central nervous system
T1258	1361-1402	http://purl.obolibrary.org/obo/GO_0007417	denotes	development of the central nervous system
T1257	4537-4548	http://purl.obolibrary.org/obo/GO_0032502	denotes	development
T1256	3013-3024	http://purl.obolibrary.org/obo/GO_0032502	denotes	development
T1255	1361-1372	http://purl.obolibrary.org/obo/GO_0032502	denotes	development
T1254	2767-2792	http://purl.obolibrary.org/obo/GO_0010467	denotes	expression of these genes
T1253	1238-1253	http://purl.obolibrary.org/obo/GO_0010467	denotes	gene expression
T1252	941-954	http://purl.obolibrary.org/obo/GO_0000394	denotes	mRNA splicing
T1251	941-954	http://purl.obolibrary.org/obo/GO_0000374	denotes	mRNA splicing
T1250	941-954	http://purl.obolibrary.org/obo/GO_0000373	denotes	mRNA splicing
T1249	941-954	http://purl.obolibrary.org/obo/GO_0000372	denotes	mRNA splicing
T1248	941-954	http://purl.obolibrary.org/obo/GO_0000398	denotes	mRNA splicing
T1247	937-954	http://purl.obolibrary.org/obo/GO_0048024	denotes	pre-mRNA splicing
T1246	1128-1136	http://purl.obolibrary.org/obo/GO_0045292	denotes	splicing
T1245	1008-1016	http://purl.obolibrary.org/obo/GO_0045292	denotes	splicing
T1244	946-954	http://purl.obolibrary.org/obo/GO_0045292	denotes	splicing
T1243	900-908	http://purl.obolibrary.org/obo/GO_0045292	denotes	splicing
T1242	5303-5316	http://purl.obolibrary.org/obo/GO_0006351	denotes	transcription
T1241	4163-4176	http://purl.obolibrary.org/obo/GO_0006351	denotes	transcription
T1240	2096-2109	http://purl.obolibrary.org/obo/GO_0006351	denotes	transcription
T1239	1944-1957	http://purl.obolibrary.org/obo/GO_0006351	denotes	transcription
T1238	602-615	http://purl.obolibrary.org/obo/GO_0006351	denotes	transcription
T1237	388-401	http://purl.obolibrary.org/obo/GO_0006351	denotes	transcription
T1236	231-244	http://purl.obolibrary.org/obo/GO_0006351	denotes	transcription
T1235	60-73	http://purl.obolibrary.org/obo/GO_0006351	denotes	transcription

GO-MF

Id	Subject	Object	Predicate	Lexical cue
T1471	2575-2581	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1470	2541-2547	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1469	214-221	http://purl.obolibrary.org/obo/GO_0005488	denotes	binding
T1482	5497-5503	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1481	5462-5468	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1480	5278-5284	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1479	5210-5216	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1478	5133-5139	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1477	5037-5043	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1476	3785-3791	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1475	3663-3669	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1474	3645-3651	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1473	3433-3439	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin
T1472	2969-2975	http://purl.obolibrary.org/obo/GO_0005344	denotes	globin

GO-CC

Id	Subject	Object	Predicate	Lexical cue
T1499	4708-4711	http://purl.obolibrary.org/obo/GO_0035301	denotes	HSC
T1498	4308-4325	http://purl.obolibrary.org/obo/GO_0043234	denotes	protein complexes
T1497	5367-5371	http://purl.obolibrary.org/obo/GO_0060417	denotes	yolk
T1496	3095-3099	http://purl.obolibrary.org/obo/GO_0060417	denotes	yolk
T1495	2637-2647	http://purl.obolibrary.org/obo/GO_0005694	denotes	Chromosome
T1494	1723-1733	http://purl.obolibrary.org/obo/GO_0005694	denotes	Chromosome
T1493	4698-4703	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T1492	3970-3974	http://purl.obolibrary.org/obo/GO_0005623	denotes	cell
T1491	986-990	http://purl.obolibrary.org/obo/GO_0005623	denotes	cell
T1490	2390-2399	http://purl.obolibrary.org/obo/GO_0000785	denotes	chromatin
T1489	551-560	http://purl.obolibrary.org/obo/GO_0000785	denotes	chromatin
T1488	2158-2164	http://purl.obolibrary.org/obo/GO_0097610	denotes	groove
T1487	427-433	http://purl.obolibrary.org/obo/GO_0097610	denotes	groove
T1486	271-277	http://purl.obolibrary.org/obo/GO_0097610	denotes	groove

sentences

Id	Subject	Object	Predicate	Lexical cue
T1221	3471-3638	Sentence	denotes	In definitive erythropoiesis, ɛ is activated and silenced autonomously [24,25], although in primitive erythropoiesis ɛ also appears to be regulated competitively [26].
T1234	5470-5612	Sentence	denotes	In the absence of Sox6, ɛy globin is ectopically expressed in the fetal liver, demonstrating that Sox6 functions in definitive erythropoiesis.
T1233	5318-5469	Sentence	denotes	In wild-type (WT) mice, Sox6 is not expressed in yolk sac blood islands, but is expressed in fetal liver, the opposite expression pattern of ɛy globin.
T1232	5223-5317	Sentence	denotes	We show that Sox6 binds to the proximal promoter of ɛy globin and represses its transcription.
T1231	5146-5222	Sentence	denotes	Here we describe and characterize the effects of Sox6 on the ɛy globin gene.
T1230	5051-5145	Sentence	denotes	The most extreme effect is the persistence of high expression of the embryonic ɛy globin gene.
T1229	4880-5050	Sentence	denotes	These effects include delayed maturation of erythrocytes (that normally enucleate prior to entering the bloodstream [27]) and higher expression of embryonic globin genes.
T1228	4792-4879	Sentence	denotes	In this study, we describe that Sox6 also exerts pleiotropic effects on erythropoiesis.
T1227	4489-4791	Sentence	denotes	In addition to playing an important role in the development of the central nervous system [8–11], cartilage [6,12,13], and muscle [14,15], it was shown that Sox6 is upregulated in long-term hematopoiesis stem cells (LT-HSC) compared with multipotent progenitors of adult mouse bone marrow lineage [28].
T1226	4357-4488	Sentence	denotes	Thus, it appears that the silencing of the ɛ gene involves a complicated network of multiple cis elements and transacting proteins.
T1225	4143-4356	Sentence	denotes	Their corresponding transcription factors, such as GATA-1, YY-1, COUP-TF, and DRED have been identified and shown to directly bind to these DNA elements (as part of protein complexes) to regulate ɛ silencing [27].
T1224	3906-4142	Sentence	denotes	Using promoter deletion analyses in transgenic mouse models and cell transfection assays, multiple DNA elements important to the silencing process have been previously identified in both the proximal and the distal ɛ gene promoter [27].
T1223	3736-3905	Sentence	denotes	All the elements responsible for silencing the ɛ globin gene are within the ɛ gene or in adjacent sequences [27], suggesting that silencing is primarily gene autonomous.
T1222	3639-3735	Sentence	denotes	The γ-globin to adult β-globin switch is controlled by promoter competition for the LCR [24,25].
T1220	3378-3470	Sentence	denotes	The mechanism of silencing of its human counterpart, ɛ globin, has been studied extensively.
T1219	3323-3377	Sentence	denotes	The ɛy gene is silenced in definitive erythroid cells.
T1218	3170-3322	Sentence	denotes	At 11.5 d post coitus (dpc), erythropoiesis shifts to the fetal liver where definitive erythroid cells express adult β globins (β major and minor) [22].
T1217	3043-3169	Sentence	denotes	In mice, erythropoiesis originates in the embryonic yolk sac where primitive erythroid cells express ɛy and βh-1 globins [22].
T1216	2963-3042	Sentence	denotes	The β-globin genes are expressed in a tissue- and development-specific fashion.
T1215	2756-2962	Sentence	denotes	High-level expression of these genes requires a regulatory element, the locus control region that is characterized by a set of nuclease hypersensitive sites spread over 25 kb located 5′ of the ɛy gene [23].
T1214	2563-2755	Sentence	denotes	The mouse β-globin genes {ɛy, βh1, β-major, and β-minor} are clustered on Chromosome 7 and they are highly homologous to their human counterparts in organizational structure and function [22].
T1213	2484-2562	Sentence	denotes	Specifically, HMG proteins have been shown to modulate β-globin genes [18–21].
T1212	2273-2483	Sentence	denotes	Modulation of DNA structure by these and other HMG proteins can mediate long-range enhancer function on both DNA and chromatin-assembled genes by bringing together distant regions of DNA and associated factors.
T1211	2004-2272	Sentence	denotes	Among the HMG box proteins distantly related to Sry (the first member identified of the Sox transcription factor family) that similarly bind to the minor groove and bend DNA, but without sequence specificity, are the ubiquitously expressed HMG1 and HMG2 proteins [17].
T1210	1877-2003	Sentence	denotes	Because the p gene functions solely in pigmentation [16], the Sox6 transcription factor is implicated in all other phenotypes.
T1209	1678-1876	Sentence	denotes	The p100H mutant allele is associated with a Chromosome 7 inversion that disrupts both the p gene and the Sox6 gene (and no other gene within 50,000 nucleotides of the chromosomal breakpoints) [14].
T1208	1540-1677	Sentence	denotes	Mice homozygous for p100H show delayed growth, develop myopathy and arterioventricular heart block, and die within 2 wk after birth [14].
T1207	1452-1539	Sentence	denotes	A Sox6-null mutant mouse (p100H) has previously been identified in our laboratory [14].
T1206	1191-1451	Sentence	denotes	Regardless of how Sox6 functions in regulating gene expression, previous studies have demonstrated that Sox6 is an important regulatory molecule that plays a role in the development of the central nervous system [8–11], cartilage [6,12,13], and muscle [14,15].
T1205	960-1190	Sentence	denotes	Depletion of Sox6 in HeLa cell extracts blocked splicing of multiple substrates, and expression of the HMG domain of either Sox6, Sox9, or Sry in the extracts restored splicing, indicating functional overlap of these proteins [7].
T1204	841-959	Sentence	denotes	Intriguingly, Sox6 has also been shown to act as a general splicing factor that participates in pre-mRNA splicing [7].
T1203	693-840	Sentence	denotes	Sox6 has been reported to be able to act as either an activator or a repressor, depending on its interactors and its target promoter context [5,6].
T1202	446-692	Sentence	denotes	Therefore, Sox proteins may perform part of their function as architectural proteins by organizing local chromatin structure and assembling other DNA-bound transcription factors into biologically active, sterically defined multiprotein complexes.
T1201	227-445	Sentence	denotes	Sox transcription factors bind to the minor groove of DNA and cause a 70°–85° bend of the DNA that leads to local conformational changes [2,3], while most other transcription factors target the major groove of DNA [4].
T1200	13-226	Sentence	denotes	Sry type HMG box (Sox6) is a member of the Sox transcription factor family characterized by the conserved high mobility group (HMG) domain, consisting of 79 amino acids involved in DNA recognition and binding [1].
T19	0-12	Sentence	denotes	Introduction
T20	13-226	Sentence	denotes	Sry type HMG box (Sox6) is a member of the Sox transcription factor family characterized by the conserved high mobility group (HMG) domain, consisting of 79 amino acids involved in DNA recognition and binding [1].
T21	227-445	Sentence	denotes	Sox transcription factors bind to the minor groove of DNA and cause a 70°–85° bend of the DNA that leads to local conformational changes [2,3], while most other transcription factors target the major groove of DNA [4].
T22	446-692	Sentence	denotes	Therefore, Sox proteins may perform part of their function as architectural proteins by organizing local chromatin structure and assembling other DNA-bound transcription factors into biologically active, sterically defined multiprotein complexes.
T23	693-840	Sentence	denotes	Sox6 has been reported to be able to act as either an activator or a repressor, depending on its interactors and its target promoter context [5,6].
T24	841-959	Sentence	denotes	Intriguingly, Sox6 has also been shown to act as a general splicing factor that participates in pre-mRNA splicing [7].
T25	960-1190	Sentence	denotes	Depletion of Sox6 in HeLa cell extracts blocked splicing of multiple substrates, and expression of the HMG domain of either Sox6, Sox9, or Sry in the extracts restored splicing, indicating functional overlap of these proteins [7].
T26	1191-1451	Sentence	denotes	Regardless of how Sox6 functions in regulating gene expression, previous studies have demonstrated that Sox6 is an important regulatory molecule that plays a role in the development of the central nervous system [8–11], cartilage [6,12,13], and muscle [14,15].
T27	1452-1539	Sentence	denotes	A Sox6-null mutant mouse (p100H) has previously been identified in our laboratory [14].
T28	1540-1677	Sentence	denotes	Mice homozygous for p100H show delayed growth, develop myopathy and arterioventricular heart block, and die within 2 wk after birth [14].
T29	1678-1876	Sentence	denotes	The p100H mutant allele is associated with a Chromosome 7 inversion that disrupts both the p gene and the Sox6 gene (and no other gene within 50,000 nucleotides of the chromosomal breakpoints) [14].
T30	1877-2003	Sentence	denotes	Because the p gene functions solely in pigmentation [16], the Sox6 transcription factor is implicated in all other phenotypes.
T31	2004-2272	Sentence	denotes	Among the HMG box proteins distantly related to Sry (the first member identified of the Sox transcription factor family) that similarly bind to the minor groove and bend DNA, but without sequence specificity, are the ubiquitously expressed HMG1 and HMG2 proteins [17].
T32	2273-2483	Sentence	denotes	Modulation of DNA structure by these and other HMG proteins can mediate long-range enhancer function on both DNA and chromatin-assembled genes by bringing together distant regions of DNA and associated factors.
T33	2484-2562	Sentence	denotes	Specifically, HMG proteins have been shown to modulate β-globin genes [18–21].
T34	2563-2755	Sentence	denotes	The mouse β-globin genes {ɛy, βh1, β-major, and β-minor} are clustered on Chromosome 7 and they are highly homologous to their human counterparts in organizational structure and function [22].
T35	2756-2962	Sentence	denotes	High-level expression of these genes requires a regulatory element, the locus control region that is characterized by a set of nuclease hypersensitive sites spread over 25 kb located 5′ of the ɛy gene [23].
T36	2963-3042	Sentence	denotes	The β-globin genes are expressed in a tissue- and development-specific fashion.
T37	3043-3169	Sentence	denotes	In mice, erythropoiesis originates in the embryonic yolk sac where primitive erythroid cells express ɛy and βh-1 globins [22].
T38	3170-3322	Sentence	denotes	At 11.5 d post coitus (dpc), erythropoiesis shifts to the fetal liver where definitive erythroid cells express adult β globins (β major and minor) [22].
T39	3323-3377	Sentence	denotes	The ɛy gene is silenced in definitive erythroid cells.
T40	3378-3470	Sentence	denotes	The mechanism of silencing of its human counterpart, ɛ globin, has been studied extensively.
T41	3471-3638	Sentence	denotes	In definitive erythropoiesis, ɛ is activated and silenced autonomously [24,25], although in primitive erythropoiesis ɛ also appears to be regulated competitively [26].
T42	3639-3735	Sentence	denotes	The γ-globin to adult β-globin switch is controlled by promoter competition for the LCR [24,25].
T43	3736-3905	Sentence	denotes	All the elements responsible for silencing the ɛ globin gene are within the ɛ gene or in adjacent sequences [27], suggesting that silencing is primarily gene autonomous.
T44	3906-4142	Sentence	denotes	Using promoter deletion analyses in transgenic mouse models and cell transfection assays, multiple DNA elements important to the silencing process have been previously identified in both the proximal and the distal ɛ gene promoter [27].
T45	4143-4356	Sentence	denotes	Their corresponding transcription factors, such as GATA-1, YY-1, COUP-TF, and DRED have been identified and shown to directly bind to these DNA elements (as part of protein complexes) to regulate ɛ silencing [27].
T46	4357-4488	Sentence	denotes	Thus, it appears that the silencing of the ɛ gene involves a complicated network of multiple cis elements and transacting proteins.
T47	4489-4791	Sentence	denotes	In addition to playing an important role in the development of the central nervous system [8–11], cartilage [6,12,13], and muscle [14,15], it was shown that Sox6 is upregulated in long-term hematopoiesis stem cells (LT-HSC) compared with multipotent progenitors of adult mouse bone marrow lineage [28].
T48	4792-4879	Sentence	denotes	In this study, we describe that Sox6 also exerts pleiotropic effects on erythropoiesis.
T49	4880-5050	Sentence	denotes	These effects include delayed maturation of erythrocytes (that normally enucleate prior to entering the bloodstream [27]) and higher expression of embryonic globin genes.
T50	5051-5145	Sentence	denotes	The most extreme effect is the persistence of high expression of the embryonic ɛy globin gene.
T51	5146-5222	Sentence	denotes	Here we describe and characterize the effects of Sox6 on the ɛy globin gene.
T52	5223-5317	Sentence	denotes	We show that Sox6 binds to the proximal promoter of ɛy globin and represses its transcription.
T53	5318-5469	Sentence	denotes	In wild-type (WT) mice, Sox6 is not expressed in yolk sac blood islands, but is expressed in fetal liver, the opposite expression pattern of ɛy globin.
T54	5470-5612	Sentence	denotes	In the absence of Sox6, ɛy globin is ectopically expressed in the fetal liver, demonstrating that Sox6 functions in definitive erythropoiesis.

ICD10

Id	Subject	Object	Predicate	Lexical cue
T1485	1595-1603	http://purl.bioontology.org/ontology/ICD10/G72.9	denotes	myopathy
T1484	4564-4571	http://purl.bioontology.org/ontology/ICD10/R45.0	denotes	nervous
T1483	1388-1395	http://purl.bioontology.org/ontology/ICD10/R45.0	denotes	nervous

simple1

Id	Subject	Object	Predicate	Lexical cue
T1695	5568-5572	Protein	denotes	Sox6
T1694	5494-5503	Protein	denotes	ɛy globin
T1693	5488-5492	Protein	denotes	Sox6
T1692	5459-5468	Protein	denotes	ɛy globin
T1691	5342-5346	Protein	denotes	Sox6
T1690	5275-5284	Protein	denotes	ɛy globin
T1689	5236-5240	Protein	denotes	Sox6
T1688	5207-5216	Protein	denotes	ɛy globin
T1687	5195-5199	Protein	denotes	Sox6
T1686	5130-5139	Protein	denotes	ɛy globin
T1685	4824-4828	Protein	denotes	Sox6
T1684	4646-4650	Protein	denotes	Sox6
T1683	4400-4401	Protein	denotes	ɛ
T1682	4339-4340	Protein	denotes	ɛ
T1681	4221-4225	Protein	denotes	DRED
T1680	4208-4215	Protein	denotes	COUP-TF
T1679	4202-4206	Protein	denotes	YY-1
T1678	4194-4200	Protein	denotes	GATA-1
T1677	4121-4122	Protein	denotes	ɛ
T1676	3812-3813	Protein	denotes	ɛ
T1675	3783-3791	Protein	denotes	ɛ globin
T1674	3661-3669	Protein	denotes	β-globin
T1673	3643-3651	Protein	denotes	γ-globin
T1672	3588-3589	Protein	denotes	ɛ
T1671	3501-3502	Protein	denotes	ɛ
T1670	3431-3439	Protein	denotes	ɛ globin
T1669	3327-3329	Protein	denotes	ɛy
T1668	3310-3315	Protein	denotes	minor
T1667	3298-3305	Protein	denotes	β major
T1666	3151-3163	Protein	denotes	βh-1 globins
T1665	3144-3146	Protein	denotes	ɛy
T1664	2949-2951	Protein	denotes	ɛy
T1663	2611-2618	Protein	denotes	β-minor
T1662	2598-2605	Protein	denotes	β-major
T1661	2593-2596	Protein	denotes	βh1
T1660	2589-2591	Protein	denotes	ɛy
T1659	2253-2257	Protein	denotes	HMG2
T1658	2244-2248	Protein	denotes	HMG1
T1657	2052-2055	Protein	denotes	Sry
T1656	1939-1943	Protein	denotes	Sox6
T1655	1889-1890	Protein	denotes	p
T1654	1784-1788	Protein	denotes	Sox6
T1653	1769-1770	Protein	denotes	p
T1652	1454-1458	Protein	denotes	Sox6
T1651	1295-1299	Protein	denotes	Sox6
T1650	1209-1213	Protein	denotes	Sox6
T1649	1099-1102	Protein	denotes	Sry
T1648	1090-1094	Protein	denotes	Sox9
T1647	1084-1088	Protein	denotes	Sox6
T1646	973-977	Protein	denotes	Sox6
T1645	855-859	Protein	denotes	Sox6
T1644	693-697	Protein	denotes	Sox6
T1643	31-35	Protein	denotes	Sox6
T1642	13-16	Protein	denotes	Sry

BioNLP16_DUT

Id	Subject	Object	Predicate	Lexical cue
T4299	5519-5528	Gene_expression	denotes	expressed
T4298	5477-5484	Negative_regulation	denotes	absence
T4297	5437-5447	Gene_expression	denotes	expression
T4296	5354-5363	Gene_expression	denotes	expressed
T4295	5398-5407	Gene_expression	denotes	expressed
T4294	5241-5246	Binding	denotes	binds
T4293	5102-5112	Gene_expression	denotes	expression
T4292	4654-4665	Positive_regulation	denotes	upregulated
T4291	4383-4392	Negative_regulation	denotes	silencing
T4290	4341-4350	Negative_regulation	denotes	silencing
T4289	4269-4273	Binding	denotes	bind
T4288	4330-4338	Regulation	denotes	regulate
T4287	3769-3778	Negative_regulation	denotes	silencing
T4286	3680-3690	Regulation	denotes	controlled
T4285	3506-3515	Positive_regulation	denotes	activated
T4284	3609-3618	Regulation	denotes	regulated
T4283	3395-3404	Negative_regulation	denotes	silencing
T4282	3338-3346	Negative_regulation	denotes	silenced
T4281	3273-3280	Gene_expression	denotes	express
T4280	3136-3143	Gene_expression	denotes	express
T4279	2140-2144	Binding	denotes	bind
T4278	2234-2243	Gene_expression	denotes	expressed
T4277	1751-1759	Negative_regulation	denotes	disrupts
T4276	1045-1055	Gene_expression	denotes	expression
T4275	1119-1127	Positive_regulation	denotes	restored
T4274	960-969	Negative_regulation	denotes	Depletion
T4273	5568-5572	Protein	denotes	Sox6
T4272	5494-5503	Protein	denotes	ɛy globin
T4271	5488-5492	Protein	denotes	Sox6
T4270	5459-5468	Protein	denotes	ɛy globin
T4269	5342-5346	Protein	denotes	Sox6
T4268	5275-5284	Protein	denotes	ɛy globin
T4267	5236-5240	Protein	denotes	Sox6
T4266	5207-5216	Protein	denotes	ɛy globin
T4265	5195-5199	Protein	denotes	Sox6
T4264	5130-5139	Protein	denotes	ɛy globin
T4263	4824-4828	Protein	denotes	Sox6
T4262	4646-4650	Protein	denotes	Sox6
T4261	4400-4401	Protein	denotes	ɛ
T4260	4339-4340	Protein	denotes	ɛ
T4259	4221-4225	Protein	denotes	DRED
T4258	4208-4215	Protein	denotes	COUP-TF
T4257	4202-4206	Protein	denotes	YY-1
T4256	4194-4200	Protein	denotes	GATA-1
T4255	4121-4122	Protein	denotes	ɛ
T4254	3812-3813	Protein	denotes	ɛ
T4253	3783-3791	Protein	denotes	ɛ globin
T4252	3661-3669	Protein	denotes	β-globin
T4251	3643-3651	Protein	denotes	γ-globin
T4250	3588-3589	Protein	denotes	ɛ
T4249	3501-3502	Protein	denotes	ɛ
T4248	3431-3439	Protein	denotes	ɛ globin
T4247	3327-3329	Protein	denotes	ɛy
T4246	3310-3315	Protein	denotes	minor
T4245	3298-3305	Protein	denotes	β major
T4244	3151-3163	Protein	denotes	βh-1 globins
T4243	3144-3146	Protein	denotes	ɛy
T4242	2949-2951	Protein	denotes	ɛy
T4241	2611-2618	Protein	denotes	β-minor
T4240	2598-2605	Protein	denotes	β-major
T4239	2593-2596	Protein	denotes	βh1
T4238	2589-2591	Protein	denotes	ɛy
T4237	2253-2257	Protein	denotes	HMG2
T4236	2244-2248	Protein	denotes	HMG1
T4235	2052-2055	Protein	denotes	Sry
T4234	1939-1943	Protein	denotes	Sox6
T4233	1889-1890	Protein	denotes	p
T4232	1784-1788	Protein	denotes	Sox6
T4231	1769-1770	Protein	denotes	p
T4230	1454-1458	Protein	denotes	Sox6
T4229	1209-1213	Protein	denotes	Sox6
T4228	1295-1299	Protein	denotes	Sox6
T4227	1099-1102	Protein	denotes	Sry
T4226	1090-1094	Protein	denotes	Sox9
T4225	1084-1088	Protein	denotes	Sox6
T4224	973-977	Protein	denotes	Sox6
T4223	855-859	Protein	denotes	Sox6
T4222	693-697	Protein	denotes	Sox6
T4221	31-35	Protein	denotes	Sox6
T4220	13-16	Protein	denotes	Sry
R3021	T4224	T4274	themeOf	Sox6,Depletion
R3025	T4225	T4276	themeOf	Sox6,expression
R3026	T4226	T4276	themeOf	Sox9,expression
R3027	T4227	T4276	themeOf	Sry,expression
R3029	T4231	T4277	themeOf	p,disrupts
R3030	T4232	T4277	themeOf	Sox6,disrupts
R3031	T4235	T4279	themeOf	Sry,bind
R3032	T4236	T4278	themeOf	HMG1,expressed
R3033	T4237	T4278	themeOf	HMG2,expressed
R3034	T4243	T4280	themeOf	ɛy,express
R3035	T4244	T4280	themeOf	βh-1 globins,express
R3036	T4245	T4281	themeOf	β major,express
R3037	T4246	T4281	themeOf	minor,express
R3038	T4247	T4282	themeOf	ɛy,silenced
R3039	T4248	T4283	themeOf	ɛ globin,silencing
R3040	T4249	T4285	themeOf	ɛ,activated
R3041	T4250	T4284	themeOf	ɛ,regulated
R3042	T4251	T4286	themeOf	γ-globin,controlled
R3043	T4253	T4287	themeOf	ɛ globin,silencing
R3044	T4258	T4289	themeOf	COUP-TF,bind
R3045	T4260	T4288	themeOf	ɛ,regulate
R3046	T4260	T4290	themeOf	ɛ,silencing
R3047	T4261	T4291	themeOf	ɛ,silencing
R3048	T4262	T4292	themeOf	Sox6,upregulated
R3049	T4264	T4293	themeOf	ɛy globin,expression
R3050	T4267	T4294	themeOf	Sox6,binds
R3051	T4268	T4294	themeOf	ɛy globin,binds
R3052	T4269	T4296	themeOf	Sox6,expressed
R3053	T4269	T4295	themeOf	Sox6,expressed
R3054	T4270	T4295	themeOf	ɛy globin,expressed
R3055	T4270	T4297	themeOf	ɛy globin,expression
R3056	T4271	T4298	themeOf	Sox6,absence
R3057	T4272	T4299	themeOf	ɛy globin,expressed
R3058	T4272	T4298	themeOf	ɛy globin,absence
R3059	T4276	T4275	themeOf	expression,restored
R3060	T4276	T4275	themeOf	expression,restored
R3061	T4276	T4275	themeOf	expression,restored

BioNLP16_Messiy

Id	Subject	Object	Predicate	Lexical cue
T2760	5437-5447	Gene_expression	denotes	expression
T2759	5398-5407	Gene_expression	denotes	expressed
T2758	5354-5363	Gene_expression	denotes	expressed
T2757	5241-5246	Binding	denotes	binds
T2756	5184-5191	Regulation	denotes	effects
T2755	5102-5112	Gene_expression	denotes	expression
T2754	4654-4665	Positive_regulation	denotes	upregulated
T2753	4383-4392	Negative_regulation	denotes	silencing
T2752	4341-4350	Negative_regulation	denotes	silencing
T2751	4330-4338	Regulation	denotes	regulate
T2750	4269-4273	Binding	denotes	bind
T2749	3769-3778	Negative_regulation	denotes	silencing
T2748	3506-3515	Positive_regulation	denotes	activated
T2747	3395-3404	Negative_regulation	denotes	silencing
T2746	3338-3346	Negative_regulation	denotes	silenced
T2745	3273-3280	Gene_expression	denotes	express
T2744	3136-3143	Gene_expression	denotes	express
T2743	2140-2144	Binding	denotes	bind
T2742	2234-2243	Gene_expression	denotes	expressed
T2741	1751-1759	Negative_regulation	denotes	disrupts
T2740	960-969	Negative_regulation	denotes	Depletion
T2739	1119-1127	Positive_regulation	denotes	restored
T2738	1045-1055	Gene_expression	denotes	expression
T2737	5568-5572	Protein	denotes	Sox6
T2736	5494-5503	Protein	denotes	ɛy globin
T2735	5488-5492	Protein	denotes	Sox6
T2734	5459-5468	Protein	denotes	ɛy globin
T2698	1939-1943	Protein	denotes	Sox6
T2697	1889-1890	Protein	denotes	p
T2696	1784-1788	Protein	denotes	Sox6
T2695	1769-1770	Protein	denotes	p
T2694	1454-1458	Protein	denotes	Sox6
T2693	1209-1213	Protein	denotes	Sox6
T2692	1295-1299	Protein	denotes	Sox6
T2691	1099-1102	Protein	denotes	Sry
T2690	1090-1094	Protein	denotes	Sox9
T2689	1084-1088	Protein	denotes	Sox6
T2703	2593-2596	Protein	denotes	βh1
T2702	2589-2591	Protein	denotes	ɛy
T2701	2253-2257	Protein	denotes	HMG2
T2700	2244-2248	Protein	denotes	HMG1
T2699	2052-2055	Protein	denotes	Sry
T2688	973-977	Protein	denotes	Sox6
T2687	855-859	Protein	denotes	Sox6
T2686	693-697	Protein	denotes	Sox6
T2685	31-35	Protein	denotes	Sox6
T2684	13-16	Protein	denotes	Sry
T2733	5342-5346	Protein	denotes	Sox6
T2732	5275-5284	Protein	denotes	ɛy globin
T2731	5236-5240	Protein	denotes	Sox6
T2730	5207-5216	Protein	denotes	ɛy globin
T2729	5195-5199	Protein	denotes	Sox6
T2728	5130-5139	Protein	denotes	ɛy globin
T2727	4824-4828	Protein	denotes	Sox6
T2726	4646-4650	Protein	denotes	Sox6
T2725	4400-4401	Protein	denotes	ɛ
T2724	4339-4340	Protein	denotes	ɛ
T2723	4221-4225	Protein	denotes	DRED
T2722	4208-4215	Protein	denotes	COUP-TF
T2721	4202-4206	Protein	denotes	YY-1
T2720	4194-4200	Protein	denotes	GATA-1
T2719	4121-4122	Protein	denotes	ɛ
T2718	3812-3813	Protein	denotes	ɛ
T2717	3783-3791	Protein	denotes	ɛ globin
T2716	3661-3669	Protein	denotes	β-globin
T2715	3643-3651	Protein	denotes	γ-globin
T2714	3588-3589	Protein	denotes	ɛ
T2713	3501-3502	Protein	denotes	ɛ
T2712	3431-3439	Protein	denotes	ɛ globin
T2711	3327-3329	Protein	denotes	ɛy
T2710	3310-3315	Protein	denotes	minor
T2709	3298-3305	Protein	denotes	β major
T2708	3151-3163	Protein	denotes	βh-1 globins
T2707	3144-3146	Protein	denotes	ɛy
T2706	2949-2951	Protein	denotes	ɛy
T2705	2611-2618	Protein	denotes	β-minor
T2704	2598-2605	Protein	denotes	β-major
T2761	5477-5484	Negative_regulation	denotes	absence
R1774	T2688	T2740	themeOf	Sox6,Depletion
R1775	T2689	T2738	themeOf	Sox6,expression
R1780	T2690	T2738	themeOf	Sox9,expression
R1782	T2691	T2738	themeOf	Sry,expression
R1786	T2696	T2741	themeOf	Sox6,disrupts
R1788	T2699	T2743	themeOf	Sry,bind
R1793	T2700	T2742	themeOf	HMG1,expressed
R1794	T2701	T2742	themeOf	HMG2,expressed
R1802	T2707	T2744	themeOf	ɛy,express
R1805	T2710	T2745	themeOf	minor,express
R1808	T2711	T2746	themeOf	ɛy,silenced
R1809	T2712	T2747	themeOf	ɛ globin,silencing
R1811	T2713	T2748	themeOf	ɛ,activated
R1816	T2717	T2749	themeOf	ɛ globin,silencing
R1820	T2720	T2750	themeOf	GATA-1,bind
R1822	T2724	T2752	themeOf	ɛ,silencing
R1826	T2725	T2753	themeOf	ɛ,silencing
R1828	T2726	T2754	themeOf	Sox6,upregulated
R1832	T2728	T2755	themeOf	ɛy globin,expression
R1836	T2729	T2756	themeOf	Sox6,effects
R1837	T2731	T2757	themeOf	Sox6,binds
R1841	T2732	T2757	themeOf	ɛy globin,binds
R1842	T2733	T2758	themeOf	Sox6,expressed
R1843	T2733	T2759	themeOf	Sox6,expressed
R1845	T2734	T2760	themeOf	ɛy globin,expression
R1847	T2735	T2761	themeOf	Sox6,absence
R1849	T2738	T2739	themeOf	expression,restored
R1851	T2738	T2739	themeOf	expression,restored
R1852	T2738	T2739	themeOf	expression,restored
R1859	T2752	T2751	themeOf	silencing,regulate

DLUT931

Id	Subject	Object	Predicate	Lexical cue
T2844	5477-5484	Negative_regulation	denotes	absence
T2843	5437-5447	Gene_expression	denotes	expression
T2842	5398-5407	Gene_expression	denotes	expressed
T2841	5354-5363	Gene_expression	denotes	expressed
T2840	5289-5298	Negative_regulation	denotes	represses
T2839	5303-5316	Transcription	denotes	transcription
T2838	5241-5246	Binding	denotes	binds
T2837	5184-5191	Regulation	denotes	effects
T2836	5102-5112	Gene_expression	denotes	expression
T2835	4853-4860	Regulation	denotes	effects
T2834	4654-4665	Positive_regulation	denotes	upregulated
T2833	4383-4392	Negative_regulation	denotes	silencing
T2832	4330-4338	Regulation	denotes	regulate
T2831	4341-4350	Negative_regulation	denotes	silencing
T2830	3769-3778	Negative_regulation	denotes	silencing
T2829	3609-3618	Regulation	denotes	regulated
T2828	3520-3528	Negative_regulation	denotes	silenced
T2827	3506-3515	Positive_regulation	denotes	activated
T2826	3395-3404	Negative_regulation	denotes	silencing
T2825	3338-3346	Negative_regulation	denotes	silenced
T2824	3273-3280	Gene_expression	denotes	express
T2823	3136-3143	Gene_expression	denotes	express
T2822	2234-2243	Gene_expression	denotes	expressed
T2821	2140-2144	Binding	denotes	bind
T2820	1944-1957	Transcription	denotes	transcription
T2819	1751-1759	Negative_regulation	denotes	disrupts
T2818	1045-1055	Gene_expression	denotes	expression
T2817	960-969	Negative_regulation	denotes	Depletion
T2816	214-221	Binding	denotes	binding
T2815	5568-5572	Protein	denotes	Sox6
T2814	5494-5503	Protein	denotes	ɛy globin
T2813	5488-5492	Protein	denotes	Sox6
T2812	5459-5468	Protein	denotes	ɛy globin
T2811	5342-5346	Protein	denotes	Sox6
T2810	5275-5284	Protein	denotes	ɛy globin
T2809	5236-5240	Protein	denotes	Sox6
T2806	5130-5139	Protein	denotes	ɛy globin
T2805	4824-4828	Protein	denotes	Sox6
T2804	4646-4650	Protein	denotes	Sox6
T2803	4400-4401	Protein	denotes	ɛ
T2802	4339-4340	Protein	denotes	ɛ
T2801	4221-4225	Protein	denotes	DRED
T2800	4208-4215	Protein	denotes	COUP-TF
T2799	4202-4206	Protein	denotes	YY-1
T2798	4194-4200	Protein	denotes	GATA-1
T2797	4121-4122	Protein	denotes	ɛ
T2796	3812-3813	Protein	denotes	ɛ
T2795	3783-3791	Protein	denotes	ɛ globin
T2794	3661-3669	Protein	denotes	β-globin
T2793	3643-3651	Protein	denotes	γ-globin
T2792	3588-3589	Protein	denotes	ɛ
T2791	3501-3502	Protein	denotes	ɛ
T2790	3431-3439	Protein	denotes	ɛ globin
T2789	3327-3329	Protein	denotes	ɛy
T2788	3310-3315	Protein	denotes	minor
T2787	3298-3305	Protein	denotes	β major
T2786	3151-3163	Protein	denotes	βh-1 globins
T2785	3144-3146	Protein	denotes	ɛy
T2784	2949-2951	Protein	denotes	ɛy
T2783	2611-2618	Protein	denotes	β-minor
T2782	2598-2605	Protein	denotes	β-major
T2781	2593-2596	Protein	denotes	βh1
T2780	2589-2591	Protein	denotes	ɛy
T2779	2253-2257	Protein	denotes	HMG2
T2778	2244-2248	Protein	denotes	HMG1
T2777	2052-2055	Protein	denotes	Sry
T2776	1939-1943	Protein	denotes	Sox6
T2775	1889-1890	Protein	denotes	p
T2774	1784-1788	Protein	denotes	Sox6
T2773	1769-1770	Protein	denotes	p
T2772	1454-1458	Protein	denotes	Sox6
T2771	1209-1213	Protein	denotes	Sox6
T2770	1295-1299	Protein	denotes	Sox6
T2769	1099-1102	Protein	denotes	Sry
T2768	1090-1094	Protein	denotes	Sox9
T2767	1084-1088	Protein	denotes	Sox6
T2766	973-977	Protein	denotes	Sox6
T2765	855-859	Protein	denotes	Sox6
T2764	693-697	Protein	denotes	Sox6
T2763	31-35	Protein	denotes	Sox6
T2762	13-16	Protein	denotes	Sry
T2807	5195-5199	Protein	denotes	Sox6
T2808	5207-5216	Protein	denotes	ɛy globin
R1850	T2768	T2818	themeOf	Sox9,expression
R1853	T2769	T2818	themeOf	Sry,expression
R1855	T2774	T2819	themeOf	Sox6,disrupts
R1860	T2779	T2822	themeOf	HMG2,expressed
R1862	T2786	T2823	themeOf	βh-1 globins,express
R1864	T2788	T2824	themeOf	minor,express
R1866	T2807	T2837	causeOf	Sox6,effects
R1869	T2791	T2828	themeOf	ɛ,silenced
R1870	T2808	T2837	themeOf	ɛy globin,effects
R1871	T2792	T2829	themeOf	ɛ,regulated
R1872	T2809	T2838	themeOf	Sox6,binds
R1873	T2809	T2840	causeOf	Sox6,represses
R1874	T2810	T2838	themeOf	ɛy globin,binds
R1875	T2810	T2839	themeOf	ɛy globin,transcription
R1876	T2811	T2841	themeOf	Sox6,expressed
R1877	T2811	T2842	themeOf	Sox6,expressed
R1878	T2795	T2830	themeOf	ɛ globin,silencing
R1879	T2812	T2843	themeOf	ɛy globin,expression
R1880	T2812	T2842	themeOf	ɛy globin,expressed
R1881	T2814	T2844	themeOf	ɛy globin,absence
R1882	T2800	T2832	causeOf	COUP-TF,regulate
R1883	T2802	T2831	themeOf	ɛ,silencing
R1884	T2803	T2833	themeOf	ɛ,silencing
R1885	T2804	T2834	themeOf	Sox6,upregulated
R1886	T2831	T2832	themeOf	silencing,regulate
R1887	T2805	T2835	themeOf	Sox6,effects
R1888	T2806	T2836	themeOf	ɛy globin,expression
R1890	T2839	T2840	themeOf	transcription,represses
R1840	T2762	T2816	themeOf	Sry,binding
R1844	T2763	T2816	themeOf	Sox6,binding
R1846	T2766	T2817	themeOf	Sox6,Depletion
R1848	T2767	T2818	themeOf	Sox6,expression
R1854	T2773	T2819	themeOf	p,disrupts
R1856	T2776	T2820	themeOf	Sox6,transcription
R1857	T2777	T2821	themeOf	Sry,bind
R1858	T2778	T2822	themeOf	HMG1,expressed
R1861	T2785	T2823	themeOf	ɛy,express
R1863	T2787	T2824	themeOf	β major,express
R1865	T2789	T2825	themeOf	ɛy,silenced
R1867	T2790	T2826	themeOf	ɛ globin,silencing
R1868	T2791	T2827	themeOf	ɛ,activated

bionlp-st-ge-2016-test-ihmc

Id	Subject	Object	Predicate	Lexical cue	Negation
T4122	2883-2906	Protein	denotes	nuclease hypersensitive
T4121	3431-3432	Protein	denotes	ɛ
T4120	5120-5129	Protein	denotes	embryonic
T4119	13-16	Protein	denotes	Sry
T4118	3246-3272	Entity	denotes	definitive erythroid cells
T4117	1056-1073	Entity	denotes	of the HMG domain
T4116	5195-5199	Protein	denotes	Sox6
T4115	1090-1094	Protein	denotes	Sox9
T4114	508-530	Protein	denotes	architectural proteins
T4113	3110-3135	Entity	denotes	primitive erythroid cells
T4112	167-190	Entity	denotes	79 amino acids involved
T4111	5203-5221	Protein	denotes	the ɛy globin gene
T4110	2390-2415	Entity	denotes	chromatin-assembled genes
T4109	2611-2619	Protein	denotes	β-minor}
T4108	2778-2792	Protein	denotes	of these genes
T4107	3779-3796	Protein	denotes	the ɛ globin gene
T4106	3719-3726	Protein	denotes	the LCR
T4105	2253-2257	Protein	denotes	HMG2
T4104	1540-1586	Protein	denotes	Mice homozygous for p100H show delayed growth,
T4103	281-284	Entity	denotes	DNA
T4102	1295-1299	Protein	denotes	Sox6
T4101	5494-5503	Protein	denotes	ɛy globin
T4100	1885-1895	Protein	denotes	the p gene
T4099	5367-5389	Entity	denotes	yolk sac blood islands
T4098	194-197	Entity	denotes	DNA
T4097	5133-5139	Protein	denotes	globin
T4096	4479-4487	Protein	denotes	proteins
T4095	5336-5340	Protein	denotes	mice
T4094	4824-4828	Protein	denotes	Sox6
T4093	2010-2030	Protein	denotes	the HMG box proteins
T4092	2382-2385	Entity	denotes	DNA
T4091	3144-3163	Protein	denotes	ɛy and βh-1 globins
T4090	4705-4711	Entity	denotes	LT-HSC
T4089	4450-4453	Protein	denotes	cis
T4088	1099-1102	Protein	denotes	Sry
T4087	4635-4650	Protein	denotes	shown that Sox6
T4086	669-681	Protein	denotes	multiprotein
T4085	2593-2596	Protein	denotes	βh1
T4084	1209-1213	Protein	denotes	Sox6
T4083	1889-1890	Protein	denotes	p
T4082	3298-3305	Protein	denotes	β major
T4081	2563-2589	Protein	denotes	The mouse β-globin genes {
T4080	592-601	Entity	denotes	DNA-bound
T4079	457-469	Protein	denotes	Sox proteins
T4078	2539-2561	Protein	denotes	β-globin genes [18–21]
T4077	4121-4122	Protein	denotes	ɛ
T4076	5275-5284	Protein	denotes	ɛy globin
T4075	3655-3676	Protein	denotes	adult β-globin switch
T4074	2400-2415	Protein	denotes	assembled genes
T4073	3144-3146	Protein	denotes	ɛy
T4072	2158-2164	Entity	denotes	groove
T4071	5247-5284	Entity	denotes	to the proximal promoter of ɛy globin
T4070	52-87	Protein	denotes	the Sox transcription factor family
T4069	3501-3502	Protein	denotes	ɛ
T4068	3431-3439	Protein	denotes	ɛ globin
T4067	2088-2123	Protein	denotes	the Sox transcription factor family
T4066	1168-1189	Protein	denotes	of these proteins [7]
T4065	1106-1118	Entity	denotes	the extracts
T4064	1716-1733	Entity	denotes	with a Chromosome
T4063	1303-1410	Entity	denotes	an important regulatory molecule that plays a role in the development of the central nervous system [8–11],
T4062	2287-2290	Entity	denotes	DNA
T4061	682-691	Entity	denotes	complexes
T4060	227-230	Protein	denotes	Sox
T4059	437-440	Entity	denotes	DNA
T4058	2624-2647	Entity	denotes	clustered on Chromosome
T4057	3639-3651	Protein	denotes	The γ-globin
T4056	2539-2561	Protein	denotes	β-globin genes [18–21]
T4055	1017-1039	Entity	denotes	of multiple substrates
T4054	4005-4008	Entity	denotes	DNA
T4053	5113-5144	Protein	denotes	of the embryonic ɛy globin gene
T4052	2092-2095	Protein	denotes	Sox
T4051	3081-3094	Protein	denotes	the embryonic
T4050	5336-5346	Protein	denotes	mice, Sox6
T4049	4339-4340	Protein	denotes	ɛ
T4048	2589-2591	Protein	denotes	ɛy
T4047	5210-5216	Protein	denotes	globin
T4046	5459-5468	Protein	denotes	ɛy globin
T4045	1765-1775	Protein	denotes	the p gene
T4044	3095-3099	Entity	denotes	yolk
T4043	1799-1869	Protein	denotes	no other gene within 50,000 nucleotides of the chromosomal breakpoints
T4042	3193-3196	Entity	denotes	dpc
T4041	806-839	Entity	denotes	its target promoter context [5,6]
T4040	1560-1586	Entity	denotes	p100H show delayed growth,
T4039	2453-2459	Entity	denotes	of DNA
T4038	457-460	Protein	denotes	Sox
T4037	2945-2961	Protein	denotes	the ɛy gene [23]
T4036	5037-5043	Protein	denotes	globin
T4035	4110-4141	Entity	denotes	the distal ɛ gene promoter [27]
T4034	56-59	Protein	denotes	Sox
T4033	3808-3818	Protein	denotes	the ɛ gene
T4032	1678-1701	Protein	denotes	The p100H mutant allele
T4031	744-756	Entity	denotes	an activator
T4030	4921-4936	Entity	denotes	of erythrocytes
T4219	1099-1136	Binding	denotes	Sry in the extracts restored splicing
T4218	2756-2792	Gene_expression	denotes	High-level expression of these genes
T4217	4330-4340	Regulation	denotes	regulate ɛ
T4216	5097-5144	Gene_expression	denotes	high expression of the embryonic ɛy globin gene
T4215	2400-2415	Binding	denotes	assembled genes
T4214	3501-3515	Positive_regulation	denotes	ɛ is activated
T4213	586-623	Binding	denotes	other DNA-bound transcription factors
T4212	1678-1735	Binding	denotes	The p100H mutant allele is associated with a Chromosome 7
T4211	1227-1254	Regulation	denotes	regulating gene expression,
T4210	2498-2561	Regulation	denotes	HMG proteins have been shown to modulate β-globin genes [18–21]
T4209	227-284	Binding	denotes	Sox transcription factors bind to the minor groove of DNA
T4208	2624-2647	Binding	denotes	clustered on Chromosome
T4207	5236-5284	Binding	denotes	Sox6 binds to the proximal promoter of ɛy globin
T4206	3224-3316	Gene_expression	denotes	the fetal liver where definitive erythroid cells express adult β globins (β major and minor)
T4205	5470-5611	Gene_expression	denotes	In the absence of Sox6, ɛy globin is ectopically expressed in the fetal liver, demonstrating that Sox6 functions in definitive erythropoiesis
T4204	3043-3094	Positive_regulation	denotes	In mice, erythropoiesis originates in the embryonic
T4203	2963-3041	Gene_expression	denotes	The β-globin genes are expressed in a tissue- and development-specific fashion
T4202	534-623	Binding	denotes	organizing local chromatin structure and assembling other DNA-bound transcription factors
T4201	3104-3163	Gene_expression	denotes	where primitive erythroid cells express ɛy and βh-1 globins
T4200	3323-3376	Negative_regulation	denotes	The ɛy gene is silenced in definitive erythroid cells
T4199	2217-2248	Gene_expression	denotes	the ubiquitously expressed HMG1
T4198	5318-5389	Gene_expression	denotes	In wild-type (WT) mice, Sox6 is not expressed in yolk sac blood islands	true
T4197	5006-5049	Gene_expression	denotes	higher expression of embryonic globin genes
T4196	1935-1964	Transcription	denotes	the Sox6 transcription factor
T4195	4635-4665	Positive_regulation	denotes	shown that Sox6 is upregulated
T4194	5236-5316	Negative_regulation	denotes	Sox6 binds to the proximal promoter of ɛy globin and represses its transcription
T4193	3765-3796	Negative_regulation	denotes	for silencing the ɛ globin gene
T4192	4379-4406	Negative_regulation	denotes	the silencing of the ɛ gene
T4191	417-444	Entity	denotes	the major groove of DNA [4]
T4190	5024-5049	Protein	denotes	of embryonic globin genes
T4189	2148-2178	Entity	denotes	the minor groove and bend DNA,
T4188	2563-2589	Protein	denotes	The mouse β-globin genes {
T4187	970-977	Protein	denotes	of Sox6
T4186	4221-4225	Protein	denotes	DRED
T4185	2010-2030	Entity	denotes	the HMG box proteins
T4184	258-284	Entity	denotes	to the minor groove of DNA
T4183	2390-2415	Entity	denotes	chromatin-assembled genes
T4182	3095-3168	Entity	denotes	yolk sac where primitive erythroid cells express ɛy and βh-1 globins [22]
T4181	4194-4200	Protein	denotes	GATA-1
T4180	3310-3315	Protein	denotes	minor
T4179	4669-4712	Entity	denotes	long-term hematopoiesis stem cells (LT-HSC)
T4178	5485-5492	Protein	denotes	of Sox6
T4177	2253-2266	Protein	denotes	HMG2 proteins
T4176	981-999	Entity	denotes	HeLa cell extracts
T4175	586-623	Protein	denotes	other DNA-bound transcription factors
T4149	5113-5144	Protein	denotes	of the embryonic ɛy globin gene
T4148	2963-2981	Protein	denotes	The β-globin genes
T4147	31-35	Protein	denotes	Sox6
T4146	5203-5221	Protein	denotes	the ɛy globin gene
T4145	3151-3155	Protein	denotes	βh-1
T4144	227-252	Protein	denotes	Sox transcription factors
T4143	5024-5049	Protein	denotes	of embryonic globin genes
T4142	3812-3813	Protein	denotes	ɛ
T4141	2598-2605	Protein	denotes	β-major
T4140	3912-3920	Entity	denotes	promoter
T4139	1784-1788	Protein	denotes	Sox6
T4138	2945-2961	Protein	denotes	the ɛy gene [23]
T4137	170-175	Entity	denotes	amino
T4136	4202-4206	Protein	denotes	YY-1
T4135	3281-3296	Protein	denotes	adult β globins
T4134	3889-3904	Protein	denotes	gene autonomous
T4133	1939-1943	Protein	denotes	Sox6
T4132	3323-3334	Protein	denotes	The ɛy gene
T4131	3350-3376	Entity	denotes	definitive erythroid cells
T4130	145-152	Entity	denotes	domain,
T4129	2498-2510	Protein	denotes	HMG proteins
T4128	3779-3796	Protein	denotes	the ɛ globin gene
T4127	1769-1770	Protein	denotes	p
T4126	3691-3702	Entity	denotes	by promoter
T4125	4393-4406	Protein	denotes	of the ɛ gene
T4124	4208-4215	Protein	denotes	COUP-TF
T4123	1478-1483	Entity	denotes	p100H
T4160	1084-1095	Protein	denotes	Sox6, Sox9,
T4159	5568-5572	Protein	denotes	Sox6
T4158	4305-4325	Entity	denotes	of protein complexes
T4157	855-859	Protein	denotes	Sox6
T4156	4110-4141	Protein	denotes	the distal ɛ gene promoter [27]
T4155	2883-2919	Entity	denotes	nuclease hypersensitive sites spread
T4154	2314-2332	Protein	denotes	other HMG proteins
T4153	2963-2981	Protein	denotes	The β-globin genes
T4152	3655-3676	Entity	denotes	adult β-globin switch
T4151	5236-5240	Protein	denotes	Sox6
T4150	1780-1870	Protein	denotes	the Sox6 gene (and no other gene within 50,000 nucleotides of the chromosomal breakpoints)
T4174	4400-4401	Protein	denotes	ɛ
T4173	551-560	Entity	denotes	chromatin
T4172	310-320	Entity	denotes	of the DNA
T4171	13-36	Entity	denotes	Sry type HMG box (Sox6)
T4170	2217-2248	Protein	denotes	the ubiquitously expressed HMG1
T4169	3588-3589	Protein	denotes	ɛ
T4168	1820-1869	Entity	denotes	50,000 nucleotides of the chromosomal breakpoints
T4167	4283-4286	Entity	denotes	DNA
T4166	693-697	Protein	denotes	Sox6
T4165	3046-3050	Protein	denotes	mice
T4164	3783-3784	Protein	denotes	ɛ
T4163	3327-3329	Protein	denotes	ɛy
T4162	2049-2124	Protein	denotes	to Sry (the first member identified of the Sox transcription factor family)
T4161	3970-3974	Entity	denotes	cell
R2959	T4032	T4212	themeOf	The p100H mutant allele,The p100H mutant allele is associated with a Chromosome 7
R2966	T4049	T4217	themeOf	ɛ,regulate ɛ
R2978	T4050	T4198	themeOf	"mice, Sox6","In wild-type (WT) mice, Sox6 is not expressed in yolk sac blood islands"
R2980	T4051	T4204	themeOf	the embryonic,"In mice, erythropoiesis originates in the embryonic"
R2988	T4058	T4208	themeOf	clustered on Chromosome,clustered on Chromosome
R2997	T4064	T4212	themeOf	with a Chromosome,The p100H mutant allele is associated with a Chromosome 7
R3001	T4069	T4214	themeOf	ɛ,ɛ is activated
R3002	T4071	T4207	themeOf	to the proximal promoter of ɛy globin,Sox6 binds to the proximal promoter of ɛy globin
R3003	T4074	T4215	themeOf	assembled genes,assembled genes
R3005	T4078	T4210	themeOf	β-globin genes [18–21],HMG proteins have been shown to modulate β-globin genes [18–21]
R3007	T4129	T4210	causeOf	HMG proteins,HMG proteins have been shown to modulate β-globin genes [18–21]
R3008	T4080	T4213	themeOf	DNA-bound,other DNA-bound transcription factors
R3009	T4132	T4200	themeOf	The ɛy gene,The ɛy gene is silenced in definitive erythroid cells
R3010	T4087	T4195	themeOf	shown that Sox6,shown that Sox6 is upregulated
R3011	T4133	T4196	themeOf	Sox6,the Sox6 transcription factor
R3012	T4135	T4206	themeOf	adult β globins,the fetal liver where definitive erythroid cells express adult β globins (β major and minor)
R3013	T4088	T4219	themeOf	Sry,Sry in the extracts restored splicing
R3014	T4091	T4201	themeOf	ɛy and βh-1 globins,where primitive erythroid cells express ɛy and βh-1 globins
R3015	T4144	T4209	themeOf	Sox transcription factors,Sox transcription factors bind to the minor groove of DNA
R3016	T4101	T4205	themeOf	ɛy globin,"In the absence of Sox6, ɛy globin is ectopically expressed in the fetal liver, demonstrating that Sox6 functions in definitive erythropoiesis"
R3017	T4148	T4203	themeOf	The β-globin genes,The β-globin genes are expressed in a tissue- and development-specific fashion
R3019	T4151	T4207	themeOf	Sox6,Sox6 binds to the proximal promoter of ɛy globin
R3020	T4108	T4218	themeOf	of these genes,High-level expression of these genes
R3022	T4170	T4199	themeOf	the ubiquitously expressed HMG1,the ubiquitously expressed HMG1
R3023	T4175	T4213	themeOf	other DNA-bound transcription factors,other DNA-bound transcription factors
R3024	T4184	T4209	themeOf	to the minor groove of DNA,Sox transcription factors bind to the minor groove of DNA
R3028	T4190	T4197	themeOf	of embryonic globin genes,higher expression of embryonic globin genes
R2962	T4035	T4077	partOf	the distal ɛ gene promoter [27],ɛ
R2983	T4053	T4216	themeOf	of the embryonic ɛy globin gene,high expression of the embryonic ɛy globin gene
R3004	T4125	T4192	themeOf	of the ɛ gene,the silencing of the ɛ gene
R3006	T4128	T4193	themeOf	the ɛ globin gene,for silencing the ɛ globin gene
R3018	T4151	T4194	causeOf	Sox6,Sox6 binds to the proximal promoter of ɛy globin and represses its transcription

bionlp-st-ge-2016-spacy-parsed

Id	Subject	Object	Predicate	Lexical cue
T3499	3196-3197	-RRB-	denotes	)
T3498	3193-3196	FW	denotes	dpc
T3497	3192-3193	-LRB-	denotes	(
T3496	3185-3191	NN	denotes	coitus
T3495	3180-3184	NN	denotes	post
T3494	3178-3179	LS	denotes	d
T3493	3173-3177	CD	denotes	11.5
T3492	3170-3172	IN	denotes	At
T3491	3168-3169	.	denotes	.
T3490	3167-3168	NNP	denotes	]
T3489	3165-3167	CD	denotes	22
T3488	3164-3165	NNP	denotes	[
T3487	3156-3163	NNS	denotes	globins
T3486	3151-3155	JJ	denotes	βh-1
T3485	3147-3150	CC	denotes	and
T3484	3144-3146	NN	denotes	ɛy
T3483	3136-3143	VBP	denotes	express
T3482	3130-3135	NNS	denotes	cells
T3481	3120-3129	JJ	denotes	erythroid
T3480	3110-3119	JJ	denotes	primitive
T3479	3104-3109	WRB	denotes	where
T3478	3100-3103	NN	denotes	sac
T3477	3095-3099	NN	denotes	yolk
T3476	3085-3094	JJ	denotes	embryonic
T3475	3081-3084	DT	denotes	the
T3474	3078-3080	IN	denotes	in
T3473	3067-3077	VBZ	denotes	originates
T3472	3052-3066	VBZ	denotes	erythropoiesis
T3471	3050-3051	,	denotes	,
T3470	3046-3050	NNS	denotes	mice
T3469	3043-3045	IN	denotes	In
T3468	3041-3042	.	denotes	.
T3467	3034-3041	NN	denotes	fashion
T3466	3013-3033	JJ	denotes	development-specific
T3465	3009-3012	CC	denotes	and
T3464	3007-3008	:	denotes	-
T3463	3001-3007	NN	denotes	tissue
T3462	2999-3000	DT	denotes	a
T3461	2996-2998	IN	denotes	in
T3460	2986-2995	VBN	denotes	expressed
T3459	2982-2985	VBP	denotes	are
T3458	2976-2981	NNS	denotes	genes
T3457	2967-2975	JJ	denotes	β-globin
T3456	2963-2966	DT	denotes	The
T3455	2961-2962	.	denotes	.
T3454	2960-2961	NNP	denotes	]
T3453	2958-2960	CD	denotes	23
T3452	2957-2958	NNP	denotes	[
T3451	2952-2956	NN	denotes	gene
T3450	2949-2951	JJ	denotes	ɛy
T3449	2945-2948	DT	denotes	the
T3448	2942-2944	IN	denotes	of
T3447	2940-2941	NN	denotes	′
T3446	2939-2940	CD	denotes	5
T3445	2931-2938	VBN	denotes	located
T3444	2928-2930	NN	denotes	kb
T3443	2925-2927	CD	denotes	25
T3442	2920-2924	IN	denotes	over
T3441	2913-2919	VBN	denotes	spread
T3440	2907-2912	NNS	denotes	sites
T3439	2892-2906	JJ	denotes	hypersensitive
T3438	2883-2891	NN	denotes	nuclease
T3437	2880-2882	IN	denotes	of
T3436	2876-2879	NN	denotes	set
T3435	2874-2875	DT	denotes	a
T3434	2871-2873	IN	denotes	by
T3433	2857-2870	VBN	denotes	characterized
T3432	2854-2856	VBZ	denotes	is
T3431	2849-2853	WDT	denotes	that
T3430	2842-2848	NN	denotes	region
T3429	2834-2841	NN	denotes	control
T3428	2828-2833	NN	denotes	locus
T3427	2824-2827	DT	denotes	the
T3426	2822-2823	,	denotes	,
T3425	2815-2822	NN	denotes	element
T3424	2804-2814	JJ	denotes	regulatory
T3423	2802-2803	DT	denotes	a
T3422	2793-2801	VBZ	denotes	requires
T3421	2787-2792	NNS	denotes	genes
T3420	2781-2786	DT	denotes	these
T3419	2778-2780	IN	denotes	of
T3418	2767-2777	NN	denotes	expression
T3417	2756-2766	JJ	denotes	High-level
T3416	2754-2755	.	denotes	.
T3415	2753-2754	NNP	denotes	]
T3414	2751-2753	CD	denotes	22
T3413	2750-2751	NNP	denotes	[
T3412	2741-2749	NN	denotes	function
T3411	2737-2740	CC	denotes	and
T3410	2727-2736	NN	denotes	structure
T3409	2712-2726	JJ	denotes	organizational
T3408	2709-2711	IN	denotes	in
T3407	2696-2708	NNS	denotes	counterparts
T3406	2690-2695	JJ	denotes	human
T3405	2684-2689	PRP$	denotes	their
T3404	2681-2683	TO	denotes	to
T3403	2670-2680	RB	denotes	homologous
T3402	2663-2669	RB	denotes	highly
T3401	2659-2662	VBP	denotes	are
T3400	2654-2658	PRP	denotes	they
T3399	2650-2653	CC	denotes	and
T3398	2648-2649	CD	denotes	7
T3397	2637-2647	NN	denotes	Chromosome
T3396	2634-2636	IN	denotes	on
T3395	2624-2633	VBN	denotes	clustered
T3394	2620-2623	VBP	denotes	are
T3393	2611-2618	JJ	denotes	β-minor
T3392	2607-2610	CC	denotes	and
T3391	2605-2606	,	denotes	,
T3390	2598-2605	NN	denotes	β-major
T3389	2596-2597	,	denotes	,
T3388	2593-2596	CD	denotes	βh1
T3387	2591-2592	,	denotes	,
T3386	2589-2591	NN	denotes	ɛy
T3385	2582-2587	NNS	denotes	genes
T3384	2573-2581	NN	denotes	β-globin
T3383	2567-2572	NN	denotes	mouse
T3382	2563-2566	DT	denotes	The
T3381	2561-2562	.	denotes	.
T3380	2560-2561	NN	denotes	]
T3379	2558-2560	CD	denotes	21
T3378	2555-2557	CD	denotes	18
T3377	2554-2555	NNP	denotes	[
T3376	2548-2553	NNS	denotes	genes
T3375	2539-2547	JJ	denotes	β-globin
T3374	2530-2538	VB	denotes	modulate
T3373	2527-2529	TO	denotes	to
T3372	2521-2526	VBN	denotes	shown
T3371	2516-2520	VBN	denotes	been
T3370	2511-2515	VBP	denotes	have
T3369	2502-2510	NNS	denotes	proteins
T3368	2498-2501	NNP	denotes	HMG
T3367	2496-2497	,	denotes	,
T3366	2484-2496	RB	denotes	Specifically
T3365	2482-2483	.	denotes	.
T3364	2475-2482	NNS	denotes	factors
T3363	2464-2474	VBN	denotes	associated
T3362	2460-2463	CC	denotes	and
T3361	2456-2459	NNP	denotes	DNA
T3360	2453-2455	IN	denotes	of
T3359	2445-2452	NNS	denotes	regions
T3358	2437-2444	JJ	denotes	distant
T3357	2428-2436	RB	denotes	together
T3356	2419-2427	VBG	denotes	bringing
T3355	2416-2418	IN	denotes	by
T3354	2410-2415	NNS	denotes	genes
T3353	2390-2409	JJ	denotes	chromatin-assembled
T3352	2386-2389	CC	denotes	and
T3351	2382-2385	NNP	denotes	DNA
T3350	2377-2381	DT	denotes	both
T3349	2374-2376	IN	denotes	on
T3348	2365-2373	NN	denotes	function
T3347	2356-2364	NN	denotes	enhancer
T3346	2345-2355	JJ	denotes	long-range
T3345	2337-2344	VB	denotes	mediate
T3344	2333-2336	MD	denotes	can
T3343	2324-2332	NNS	denotes	proteins
T3342	2320-2323	NNP	denotes	HMG
T3341	2314-2319	JJ	denotes	other
T3340	2310-2313	CC	denotes	and
T3339	2304-2309	DT	denotes	these
T3338	2301-2303	IN	denotes	by
T3337	2291-2300	NN	denotes	structure
T3336	2287-2290	NNP	denotes	DNA
T3335	2284-2286	IN	denotes	of
T3334	2273-2283	NNP	denotes	Modulation
T3333	2271-2272	.	denotes	.
T3332	2270-2271	NNP	denotes	]
T3331	2268-2270	CD	denotes	17
T3330	2267-2268	NNP	denotes	[
T3329	2258-2266	NNS	denotes	proteins
T3328	2253-2257	NNP	denotes	HMG2
T3327	2249-2252	CC	denotes	and
T3326	2244-2248	NNP	denotes	HMG1
T3325	2234-2243	VBN	denotes	expressed
T3324	2221-2233	RB	denotes	ubiquitously
T3323	2217-2220	DT	denotes	the
T3322	2213-2216	VBP	denotes	are
T3321	2211-2212	,	denotes	,
T3320	2200-2211	NN	denotes	specificity
T3319	2191-2199	NN	denotes	sequence
T3318	2183-2190	IN	denotes	without
T3317	2179-2182	CC	denotes	but
T3316	2177-2178	,	denotes	,
T3315	2174-2177	NNP	denotes	DNA
T3314	2169-2173	VB	denotes	bend
T3313	2165-2168	CC	denotes	and
T3312	2158-2164	NN	denotes	groove
T3311	2152-2157	JJ	denotes	minor
T3310	2148-2151	DT	denotes	the
T3309	2145-2147	TO	denotes	to
T3308	2140-2144	NN	denotes	bind
T3307	2130-2139	RB	denotes	similarly
T3306	2125-2129	WDT	denotes	that
T3305	2123-2124	-RRB-	denotes	)
T3304	2117-2123	NN	denotes	family
T3303	2110-2116	NN	denotes	factor
T3302	2096-2109	NN	denotes	transcription
T3301	2092-2095	NNPS	denotes	Sox
T3300	2088-2091	DT	denotes	the
T3299	2085-2087	IN	denotes	of
T3298	2074-2084	VBN	denotes	identified
T3297	2067-2073	NN	denotes	member
T3296	2061-2066	JJ	denotes	first
T3295	2057-2060	DT	denotes	the
T3294	2056-2057	-LRB-	denotes	(
T3293	2052-2055	NNP	denotes	Sry
T3292	2049-2051	TO	denotes	to
T3291	2041-2048	VBN	denotes	related
T3290	2031-2040	RB	denotes	distantly
T3289	2022-2030	NNS	denotes	proteins
T3288	2018-2021	NN	denotes	box
T3287	2014-2017	NNP	denotes	HMG
T3286	2010-2013	DT	denotes	the
T3285	2004-2009	IN	denotes	Among
T3284	2002-2003	.	denotes	.
T3247	1799-1801	DT	denotes	no
T3246	1795-1798	CC	denotes	and
T3245	1794-1795	-LRB-	denotes	(
T3244	1789-1793	NN	denotes	gene
T3243	1784-1788	NNP	denotes	Sox6
T3242	1780-1783	DT	denotes	the
T3241	1776-1779	CC	denotes	and
T3240	1771-1775	NN	denotes	gene
T3239	1769-1770	NN	denotes	p
T3238	1765-1768	DT	denotes	the
T3237	1760-1764	CC	denotes	both
T3236	1751-1759	VBZ	denotes	disrupts
T3235	1746-1750	WDT	denotes	that
T3234	1736-1745	NN	denotes	inversion
T3233	1734-1735	CD	denotes	7
T3232	1723-1733	NN	denotes	Chromosome
T3231	1721-1722	DT	denotes	a
T3230	1716-1720	IN	denotes	with
T3229	1705-1715	VBN	denotes	associated
T3228	1702-1704	VBZ	denotes	is
T3227	1695-1701	NN	denotes	allele
T3226	1688-1694	JJ	denotes	mutant
T3225	1682-1687	JJ	denotes	p100H
T3224	1678-1681	DT	denotes	The
T3223	1676-1677	.	denotes	.
T3222	1675-1676	NNP	denotes	]
T3221	1673-1675	CD	denotes	14
T3220	1672-1673	NNP	denotes	[
T3219	1666-1671	NN	denotes	birth
T3218	1660-1665	IN	denotes	after
T3217	1657-1659	NN	denotes	wk
T3216	1655-1656	CD	denotes	2
T3215	1648-1654	IN	denotes	within
T3214	1644-1647	VB	denotes	die
T3213	1640-1643	CC	denotes	and
T3212	1638-1639	,	denotes	,
T3211	1633-1638	NN	denotes	block
T3210	1627-1632	NN	denotes	heart
T3209	1608-1626	JJ	denotes	arterioventricular
T3208	1604-1607	CC	denotes	and
T3207	1595-1603	NN	denotes	myopathy
T3206	1587-1594	VB	denotes	develop
T3205	1585-1586	,	denotes	,
T3204	1579-1585	NN	denotes	growth
T3203	1571-1578	VBN	denotes	delayed
T3202	1566-1570	NN	denotes	show
T3201	1560-1565	JJ	denotes	p100H
T3200	1556-1559	IN	denotes	for
T3199	1545-1555	NNS	denotes	homozygous
T3198	1540-1544	NN	denotes	Mice
T3197	1538-1539	.	denotes	.
T3196	1537-1538	NNP	denotes	]
T3195	1535-1537	CD	denotes	14
T3194	1534-1535	NNP	denotes	[
T3193	1523-1533	NN	denotes	laboratory
T3192	1519-1522	PRP$	denotes	our
T3191	1516-1518	IN	denotes	in
T3190	1505-1515	VBN	denotes	identified
T3189	1500-1504	VBN	denotes	been
T3188	1489-1499	RB	denotes	previously
T3187	1485-1488	VBZ	denotes	has
T3186	1483-1484	-RRB-	denotes	)
T3185	1478-1483	JJ	denotes	p100H
T3184	1477-1478	-LRB-	denotes	(
T3183	1471-1476	NN	denotes	mouse
T3182	1464-1470	JJ	denotes	mutant
T3181	1454-1463	JJ	denotes	Sox6-null
T3180	1452-1453	DT	denotes	A
T3179	1450-1451	.	denotes	.
T3178	1449-1450	NNP	denotes	]
T3177	1444-1449	CD	denotes	14,15
T3176	1443-1444	NNP	denotes	[
T3175	1436-1442	NN	denotes	muscle
T3174	1432-1435	CC	denotes	and
T3173	1430-1431	,	denotes	,
T3172	1429-1430	NNP	denotes	]
T3171	1422-1429	CD	denotes	6,12,13
T3170	1421-1422	NNP	denotes	[
T3169	1411-1420	NN	denotes	cartilage
T3168	1409-1410	,	denotes	,
T3167	1408-1409	NNP	denotes	]
T3166	1406-1408	CD	denotes	11
T3165	1404-1405	CD	denotes	8
T3164	1403-1404	NN	denotes	[
T3163	1396-1402	NN	denotes	system
T3162	1388-1395	JJ	denotes	nervous
T3161	1380-1387	JJ	denotes	central
T3160	1376-1379	DT	denotes	the
T3159	1373-1375	IN	denotes	of
T3158	1361-1372	NN	denotes	development
T3157	1357-1360	DT	denotes	the
T3156	1354-1356	IN	denotes	in
T3155	1349-1353	NN	denotes	role
T3154	1347-1348	DT	denotes	a
T3153	1341-1346	VBZ	denotes	plays
T3152	1336-1340	WDT	denotes	that
T3151	1327-1335	NN	denotes	molecule
T3150	1316-1326	JJ	denotes	regulatory
T3149	1306-1315	JJ	denotes	important
T3148	1303-1305	DT	denotes	an
T3147	1300-1302	VBZ	denotes	is
T3146	1295-1299	NNP	denotes	Sox6
T3145	1290-1294	IN	denotes	that
T3144	1277-1289	VBN	denotes	demonstrated
T3143	1272-1276	VBP	denotes	have
T3142	1264-1271	NNS	denotes	studies
T3141	1255-1263	JJ	denotes	previous
T3140	1253-1254	,	denotes	,
T3139	1243-1253	NN	denotes	expression
T3138	1238-1242	NN	denotes	gene
T3137	1227-1237	VBG	denotes	regulating
T3136	1224-1226	IN	denotes	in
T3135	1214-1223	NNS	denotes	functions
T3134	1209-1213	JJ	denotes	Sox6
T3133	1205-1208	WRB	denotes	how
T3941	5611-5612	.	denotes	.
T3940	5597-5611	NNS	denotes	erythropoiesis
T3939	5586-5596	JJ	denotes	definitive
T3938	5583-5585	IN	denotes	in
T3937	5573-5582	NNS	denotes	functions
T3936	5568-5572	JJ	denotes	Sox6
T3935	5563-5567	IN	denotes	that
T3934	5549-5562	VBG	denotes	demonstrating
T3933	5547-5548	,	denotes	,
T3932	5542-5547	NN	denotes	liver
T3931	5536-5541	JJ	denotes	fetal
T3930	5532-5535	DT	denotes	the
T3929	5529-5531	IN	denotes	in
T3928	5519-5528	VBN	denotes	expressed
T3927	5507-5518	RB	denotes	ectopically
T3926	5504-5506	VBZ	denotes	is
T3925	5497-5503	NN	denotes	globin
T3924	5494-5496	JJ	denotes	ɛy
T3923	5492-5493	,	denotes	,
T3922	5488-5492	NNP	denotes	Sox6
T3921	5485-5487	IN	denotes	of
T3920	5477-5484	NN	denotes	absence
T3919	5473-5476	DT	denotes	the
T3918	5470-5472	IN	denotes	In
T3917	5468-5469	.	denotes	.
T3916	5462-5468	NN	denotes	globin
T3915	5459-5461	JJ	denotes	ɛy
T3914	5456-5458	IN	denotes	of
T3913	5448-5455	NN	denotes	pattern
T3912	5437-5447	NN	denotes	expression
T3911	5428-5436	JJ	denotes	opposite
T3910	5424-5427	DT	denotes	the
T3909	5422-5423	,	denotes	,
T3908	5417-5422	NN	denotes	liver
T3907	5411-5416	JJ	denotes	fetal
T3906	5408-5410	IN	denotes	in
T3905	5398-5407	VBN	denotes	expressed
T3904	5395-5397	VBZ	denotes	is
T3903	5391-5394	CC	denotes	but
T3902	5389-5390	,	denotes	,
T3901	5382-5389	NNS	denotes	islands
T3900	5376-5381	NN	denotes	blood
T3899	5372-5375	NN	denotes	sac
T3898	5367-5371	NN	denotes	yolk
T3897	5364-5366	IN	denotes	in
T3896	5354-5363	VBN	denotes	expressed
T3895	5350-5353	RB	denotes	not
T3894	5347-5349	VBZ	denotes	is
T3893	5342-5346	NNP	denotes	Sox6
T3892	5340-5341	,	denotes	,
T3891	5336-5340	NNS	denotes	mice
T3890	5334-5335	-RRB-	denotes	)
T3889	5332-5334	NNP	denotes	WT
T3888	5331-5332	-LRB-	denotes	(
T3887	5321-5330	JJ	denotes	wild-type
T3886	5318-5320	IN	denotes	In
T3885	5316-5317	.	denotes	.
T3884	5303-5316	NN	denotes	transcription
T3883	5299-5302	PRP$	denotes	its
T3882	5289-5298	VBZ	denotes	represses
T3881	5285-5288	CC	denotes	and
T3880	5278-5284	NN	denotes	globin
T3879	5275-5277	JJ	denotes	ɛy
T3878	5272-5274	IN	denotes	of
T3877	5263-5271	NN	denotes	promoter
T3876	5254-5262	JJ	denotes	proximal
T3875	5250-5253	DT	denotes	the
T3874	5247-5249	TO	denotes	to
T3873	5241-5246	NNS	denotes	binds
T3872	5236-5240	JJ	denotes	Sox6
T3871	5231-5235	IN	denotes	that
T3870	5226-5230	VBP	denotes	show
T3869	5223-5225	PRP	denotes	We
T3868	5221-5222	.	denotes	.
T3867	5217-5221	NN	denotes	gene
T3866	5210-5216	NN	denotes	globin
T3865	5207-5209	JJ	denotes	ɛy
T3864	5203-5206	DT	denotes	the
T3863	5200-5202	IN	denotes	on
T3862	5195-5199	NNP	denotes	Sox6
T3861	5192-5194	IN	denotes	of
T3860	5184-5191	NNS	denotes	effects
T3859	5180-5183	DT	denotes	the
T3858	5167-5179	VBP	denotes	characterize
T3857	5163-5166	CC	denotes	and
T3856	5154-5162	VBP	denotes	describe
T3855	5151-5153	PRP	denotes	we
T3854	5146-5150	RB	denotes	Here
T3853	5144-5145	.	denotes	.
T3852	5140-5144	NN	denotes	gene
T3851	5133-5139	NN	denotes	globin
T3850	5130-5132	NN	denotes	ɛy
T3849	5120-5129	JJ	denotes	embryonic
T3848	5116-5119	DT	denotes	the
T3847	5113-5115	IN	denotes	of
T3846	5102-5112	NN	denotes	expression
T3845	5097-5101	JJ	denotes	high
T3844	5094-5096	IN	denotes	of
T3843	5082-5093	NN	denotes	persistence
T3842	5078-5081	DT	denotes	the
T3841	5075-5077	VBZ	denotes	is
T3840	5068-5074	NN	denotes	effect
T3839	5060-5067	JJ	denotes	extreme
T3838	5055-5059	RBS	denotes	most
T3837	5051-5054	DT	denotes	The
T3836	5049-5050	.	denotes	.
T3835	5044-5049	NNS	denotes	genes
T3834	5037-5043	NN	denotes	globin
T3833	5027-5036	JJ	denotes	embryonic
T3832	5024-5026	IN	denotes	of
T3831	5013-5023	NN	denotes	expression
T3830	5006-5012	JJR	denotes	higher
T3829	5002-5005	CC	denotes	and
T3828	5000-5001	-RRB-	denotes	)
T3827	4999-5000	NNP	denotes	]
T3826	4997-4999	CD	denotes	27
T3825	4996-4997	NNP	denotes	[
T3824	4984-4995	NN	denotes	bloodstream
T3823	4980-4983	DT	denotes	the
T3822	4971-4979	VBG	denotes	entering
T3821	4968-4970	TO	denotes	to
T3820	4962-4967	RB	denotes	prior
T3819	4952-4961	JJ	denotes	enucleate
T3818	4943-4951	RB	denotes	normally
T3817	4938-4942	IN	denotes	that
T3816	4937-4938	-LRB-	denotes	(
T3815	4924-4936	NNS	denotes	erythrocytes
T3814	4921-4923	IN	denotes	of
T3813	4910-4920	NN	denotes	maturation
T3812	4902-4909	VBN	denotes	delayed
T3811	4894-4901	VBP	denotes	include
T3810	4886-4893	NNS	denotes	effects
T3809	4880-4885	DT	denotes	These
T3808	4878-4879	.	denotes	.
T3807	4864-4878	NN	denotes	erythropoiesis
T3806	4861-4863	IN	denotes	on
T3805	4853-4860	NNS	denotes	effects
T3804	4841-4852	JJ	denotes	pleiotropic
T3803	4834-4840	VBZ	denotes	exerts
T3802	4829-4833	RB	denotes	also
T3801	4824-4828	NNP	denotes	Sox6
T3800	4819-4823	IN	denotes	that
T3799	4810-4818	VBP	denotes	describe
T3798	4807-4809	PRP	denotes	we
T3797	4805-4806	,	denotes	,
T3796	4800-4805	NN	denotes	study
T3795	4795-4799	DT	denotes	this
T3794	4792-4794	IN	denotes	In
T3793	4790-4791	.	denotes	.
T3792	4789-4790	NNP	denotes	]
T3791	4787-4789	CD	denotes	28
T3790	4786-4787	NNP	denotes	[
T3789	4778-4785	NN	denotes	lineage
T3788	4771-4777	NN	denotes	marrow
T3787	4766-4770	NN	denotes	bone
T3786	4760-4765	NN	denotes	mouse
T3785	4754-4759	NN	denotes	adult
T3784	4751-4753	IN	denotes	of
T3783	4739-4750	NNS	denotes	progenitors
T3782	4727-4738	JJ	denotes	multipotent
T3781	4722-4726	IN	denotes	with
T3780	4713-4721	VBN	denotes	compared
T3779	4711-4712	-RRB-	denotes	)
T3778	4705-4711	NNP	denotes	LT-HSC
T3777	4704-4705	-LRB-	denotes	(
T3776	4698-4703	NNS	denotes	cells
T3775	4693-4697	NN	denotes	stem
T3774	4679-4692	NN	denotes	hematopoiesis
T3773	4669-4678	JJ	denotes	long-term
T3772	4666-4668	IN	denotes	in
T3771	4654-4665	VBN	denotes	upregulated
T3770	4651-4653	VBZ	denotes	is
T3769	4646-4650	NNP	denotes	Sox6
T3768	4641-4645	IN	denotes	that
T3767	4635-4640	VBN	denotes	shown
T3766	4631-4634	VBD	denotes	was
T3765	4628-4630	PRP	denotes	it
T3764	4626-4627	,	denotes	,
T3763	4625-4626	NNP	denotes	]
T3762	4620-4625	CD	denotes	14,15
T3761	4619-4620	NNP	denotes	[
T3760	4612-4618	NN	denotes	muscle
T3759	4608-4611	CC	denotes	and
T3758	4606-4607	,	denotes	,
T3757	4605-4606	NNP	denotes	]
T3756	4598-4605	CD	denotes	6,12,13
T3755	4597-4598	NNP	denotes	[
T3754	4587-4596	NN	denotes	cartilage
T3753	4585-4586	,	denotes	,
T3752	4584-4585	NNP	denotes	]
T3689	4257-4259	TO	denotes	to
T3688	4251-4256	VBN	denotes	shown
T3687	4247-4250	CC	denotes	and
T3686	4236-4246	VBN	denotes	identified
T3685	4231-4235	VBN	denotes	been
T3684	4226-4230	VBP	denotes	have
T3683	4221-4225	NNP	denotes	DRED
T3682	4217-4220	CC	denotes	and
T3681	4215-4216	,	denotes	,
T3680	4208-4215	NNP	denotes	COUP-TF
T3679	4206-4207	,	denotes	,
T3678	4202-4206	NNP	denotes	YY-1
T3677	4200-4201	,	denotes	,
T3676	4194-4200	NNP	denotes	GATA-1
T3675	4191-4193	IN	denotes	as
T3674	4186-4190	JJ	denotes	such
T3673	4184-4185	,	denotes	,
T3672	4177-4184	NNS	denotes	factors
T3671	4163-4176	NN	denotes	transcription
T3670	4149-4162	JJ	denotes	corresponding
T3669	4143-4148	PRP$	denotes	Their
T3668	4141-4142	.	denotes	.
T3667	4140-4141	NNP	denotes	]
T3666	4138-4140	CD	denotes	27
T3665	4137-4138	NNP	denotes	[
T3664	4128-4136	NN	denotes	promoter
T3663	4123-4127	NN	denotes	gene
T3662	4121-4122	NN	denotes	ɛ
T3661	4114-4120	JJ	denotes	distal
T3660	4110-4113	DT	denotes	the
T3659	4106-4109	CC	denotes	and
T3658	4097-4105	NN	denotes	proximal
T3657	4093-4096	DT	denotes	the
T3656	4088-4092	DT	denotes	both
T3655	4085-4087	IN	denotes	in
T3654	4074-4084	VBN	denotes	identified
T3653	4063-4073	RB	denotes	previously
T3652	4058-4062	VBN	denotes	been
T3651	4053-4057	VBP	denotes	have
T3650	4045-4052	NN	denotes	process
T3649	4035-4044	VBG	denotes	silencing
T3648	4031-4034	DT	denotes	the
T3647	4028-4030	TO	denotes	to
T3646	4018-4027	JJ	denotes	important
T3645	4009-4017	NNS	denotes	elements
T3644	4005-4008	NNP	denotes	DNA
T3643	3996-4004	JJ	denotes	multiple
T3642	3994-3995	,	denotes	,
T3641	3988-3994	NNS	denotes	assays
T3640	3975-3987	NN	denotes	transfection
T3639	3970-3974	NN	denotes	cell
T3638	3966-3969	CC	denotes	and
T3637	3959-3965	NNS	denotes	models
T3636	3953-3958	NN	denotes	mouse
T3635	3942-3952	JJ	denotes	transgenic
T3634	3939-3941	IN	denotes	in
T3633	3930-3938	NNS	denotes	analyses
T3632	3921-3929	NN	denotes	deletion
T3631	3912-3920	NN	denotes	promoter
T3630	3906-3911	VBG	denotes	Using
T3629	3904-3905	.	denotes	.
T3628	3894-3904	JJ	denotes	autonomous
T3627	3889-3893	NN	denotes	gene
T3626	3879-3888	RB	denotes	primarily
T3625	3876-3878	VBZ	denotes	is
T3624	3866-3875	VBG	denotes	silencing
T3623	3861-3865	IN	denotes	that
T3622	3850-3860	VBG	denotes	suggesting
T3621	3848-3849	,	denotes	,
T3620	3847-3848	NNP	denotes	]
T3619	3845-3847	CD	denotes	27
T3618	3844-3845	NNP	denotes	[
T3617	3834-3843	NNS	denotes	sequences
T3616	3825-3833	JJ	denotes	adjacent
T3615	3822-3824	IN	denotes	in
T3614	3819-3821	CC	denotes	or
T3613	3814-3818	NN	denotes	gene
T3612	3812-3813	NN	denotes	ɛ
T3611	3808-3811	DT	denotes	the
T3610	3801-3807	IN	denotes	within
T3609	3797-3800	VBP	denotes	are
T3608	3792-3796	NN	denotes	gene
T3607	3785-3791	NN	denotes	globin
T3606	3783-3784	NN	denotes	ɛ
T3605	3779-3782	DT	denotes	the
T3604	3769-3778	VBG	denotes	silencing
T3603	3765-3768	IN	denotes	for
T3602	3753-3764	JJ	denotes	responsible
T3601	3744-3752	NNS	denotes	elements
T3600	3740-3743	DT	denotes	the
T3599	3736-3739	PDT	denotes	All
T3598	3734-3735	.	denotes	.
T3597	3733-3734	NNP	denotes	]
T3596	3728-3733	CD	denotes	24,25
T3595	3727-3728	NNP	denotes	[
T3594	3723-3726	NNP	denotes	LCR
T3593	3719-3722	DT	denotes	the
T3592	3715-3718	IN	denotes	for
T3591	3703-3714	NN	denotes	competition
T3590	3694-3702	NN	denotes	promoter
T3589	3691-3693	IN	denotes	by
T3588	3680-3690	VBN	denotes	controlled
T3587	3677-3679	VBZ	denotes	is
T3586	3670-3676	NN	denotes	switch
T3585	3661-3669	NN	denotes	β-globin
T3584	3655-3660	NN	denotes	adult
T3583	3652-3654	TO	denotes	to
T3582	3643-3651	NN	denotes	γ-globin
T3581	3639-3642	DT	denotes	The
T3580	3637-3638	.	denotes	.
T3579	3636-3637	NNP	denotes	]
T3578	3634-3636	CD	denotes	26
T3577	3633-3634	NNP	denotes	[
T3576	3619-3632	RB	denotes	competitively
T3575	3609-3618	VBN	denotes	regulated
T3574	3606-3608	VB	denotes	be
T3573	3603-3605	TO	denotes	to
T3572	3595-3602	VBZ	denotes	appears
T3571	3590-3594	RB	denotes	also
T3570	3588-3589	NN	denotes	ɛ
T3569	3573-3587	NN	denotes	erythropoiesis
T3568	3563-3572	JJ	denotes	primitive
T3567	3560-3562	IN	denotes	in
T3566	3551-3559	IN	denotes	although
T3565	3549-3550	,	denotes	,
T3564	3548-3549	NNP	denotes	]
T3563	3543-3548	CD	denotes	24,25
T3562	3542-3543	NNP	denotes	[
T3561	3529-3541	RB	denotes	autonomously
T3560	3520-3528	VBN	denotes	silenced
T3559	3516-3519	CC	denotes	and
T3558	3506-3515	VBN	denotes	activated
T3557	3503-3505	VBZ	denotes	is
T3556	3501-3502	NN	denotes	ɛ
T3555	3499-3500	,	denotes	,
T3554	3485-3499	NNS	denotes	erythropoiesis
T3553	3474-3484	JJ	denotes	definitive
T3552	3471-3473	IN	denotes	In
T3551	3469-3470	.	denotes	.
T3550	3458-3469	RB	denotes	extensively
T3549	3450-3457	VBN	denotes	studied
T3548	3445-3449	VBN	denotes	been
T3547	3441-3444	VBZ	denotes	has
T3546	3439-3440	,	denotes	,
T3545	3433-3439	NN	denotes	globin
T3544	3431-3432	NN	denotes	ɛ
T3543	3429-3430	,	denotes	,
T3542	3418-3429	NN	denotes	counterpart
T3541	3412-3417	JJ	denotes	human
T3540	3408-3411	PRP$	denotes	its
T3539	3405-3407	IN	denotes	of
T3538	3395-3404	VBG	denotes	silencing
T3537	3392-3394	IN	denotes	of
T3536	3382-3391	NN	denotes	mechanism
T3535	3378-3381	DT	denotes	The
T3534	3376-3377	.	denotes	.
T3533	3371-3376	NNS	denotes	cells
T3532	3361-3370	JJ	denotes	erythroid
T3531	3350-3360	JJ	denotes	definitive
T3530	3347-3349	IN	denotes	in
T3529	3338-3346	VBN	denotes	silenced
T3528	3335-3337	VBZ	denotes	is
T3527	3330-3334	NN	denotes	gene
T3526	3327-3329	JJ	denotes	ɛy
T3525	3323-3326	DT	denotes	The
T3524	3321-3322	.	denotes	.
T3523	3320-3321	NNP	denotes	]
T3522	3318-3320	CD	denotes	22
T3521	3317-3318	NNP	denotes	[
T3520	3315-3316	-RRB-	denotes	)
T3519	3310-3315	JJ	denotes	minor
T3518	3306-3309	CC	denotes	and
T3517	3300-3305	JJ	denotes	major
T3516	3298-3299	FW	denotes	β
T3515	3297-3298	-LRB-	denotes	(
T3514	3289-3296	NNS	denotes	globins
T3513	3287-3288	NN	denotes	β
T3512	3281-3286	NN	denotes	adult
T3511	3273-3280	VBP	denotes	express
T3510	3267-3272	NNS	denotes	cells
T3509	3257-3266	JJ	denotes	erythroid
T3508	3246-3256	JJ	denotes	definitive
T3507	3240-3245	WRB	denotes	where
T3506	3234-3239	NN	denotes	liver
T3505	3228-3233	JJ	denotes	fetal
T3504	3224-3227	DT	denotes	the
T3503	3221-3223	TO	denotes	to
T3502	3214-3220	NNS	denotes	shifts
T3501	3199-3213	VBZ	denotes	erythropoiesis
T3500	3197-3198	,	denotes	,
T3132	1202-1204	IN	denotes	of
T3131	1191-1201	RB	denotes	Regardless
T3130	1189-1190	.	denotes	.
T3129	1188-1189	NNP	denotes	]
T3128	1187-1188	CD	denotes	7
T3127	1186-1187	VBP	denotes	[
T3126	1177-1185	NNS	denotes	proteins
T3125	1171-1176	DT	denotes	these
T3124	1168-1170	IN	denotes	of
T3123	1160-1167	VBP	denotes	overlap
T3122	1149-1159	JJ	denotes	functional
T3121	1138-1148	VBG	denotes	indicating
T3120	1136-1137	,	denotes	,
T3119	1128-1136	NN	denotes	splicing
T3118	1119-1127	VBD	denotes	restored
T3117	1110-1118	NNS	denotes	extracts
T3116	1106-1109	DT	denotes	the
T3115	1103-1105	IN	denotes	in
T3114	1099-1102	NNP	denotes	Sry
T3113	1096-1098	CC	denotes	or
T3112	1094-1095	,	denotes	,
T3111	1090-1094	NNP	denotes	Sox9
T3110	1088-1089	,	denotes	,
T3109	1084-1088	NNP	denotes	Sox6
T3108	1077-1083	DT	denotes	either
T3107	1074-1076	IN	denotes	of
T3106	1067-1073	NN	denotes	domain
T3105	1063-1066	NNP	denotes	HMG
T3104	1059-1062	DT	denotes	the
T3103	1056-1058	IN	denotes	of
T3102	1045-1055	NN	denotes	expression
T3101	1041-1044	CC	denotes	and
T3100	1039-1040	,	denotes	,
T3099	1029-1039	NNS	denotes	substrates
T3098	1020-1028	JJ	denotes	multiple
T3097	1017-1019	IN	denotes	of
T3096	1008-1016	NN	denotes	splicing
T3095	1000-1007	VBN	denotes	blocked
T3094	991-999	VBZ	denotes	extracts
T3093	986-990	NN	denotes	cell
T3092	981-985	NNP	denotes	HeLa
T3091	978-980	IN	denotes	in
T3090	973-977	NNP	denotes	Sox6
T3089	970-972	IN	denotes	of
T3088	960-969	NN	denotes	Depletion
T3087	958-959	.	denotes	.
T3086	957-958	NNP	denotes	]
T3085	956-957	CD	denotes	7
T3084	955-956	NN	denotes	[
T3083	946-954	NN	denotes	splicing
T3082	937-945	JJ	denotes	pre-mRNA
T3081	934-936	IN	denotes	in
T3080	921-933	VBZ	denotes	participates
T3079	916-920	WDT	denotes	that
T3078	909-915	NN	denotes	factor
T3077	900-908	NN	denotes	splicing
T3076	892-899	JJ	denotes	general
T3075	890-891	DT	denotes	a
T3074	887-889	IN	denotes	as
T3073	883-886	VB	denotes	act
T3072	880-882	TO	denotes	to
T3071	874-879	VBN	denotes	shown
T3070	869-873	VBN	denotes	been
T3069	864-868	RB	denotes	also
T3068	860-863	VBZ	denotes	has
T3067	855-859	NNP	denotes	Sox6
T3066	853-854	,	denotes	,
T3065	841-853	RB	denotes	Intriguingly
T3064	839-840	.	denotes	.
T3063	838-839	NNP	denotes	]
T3062	835-838	CD	denotes	5,6
T3061	834-835	NNP	denotes	[
T3060	826-833	NN	denotes	context
T3059	817-825	NN	denotes	promoter
T3058	810-816	NN	denotes	target
T3057	806-809	PRP$	denotes	its
T3056	802-805	CC	denotes	and
T3055	790-801	NNS	denotes	interactors
T3054	786-789	PRP$	denotes	its
T3053	783-785	IN	denotes	on
T3052	773-782	VBG	denotes	depending
T3051	771-772	,	denotes	,
T3050	762-771	NN	denotes	repressor
T3049	760-761	DT	denotes	a
T3048	757-759	CC	denotes	or
T3047	747-756	NN	denotes	activator
T3046	744-746	DT	denotes	an
T3045	737-743	DT	denotes	either
T3044	734-736	IN	denotes	as
T3043	730-733	VB	denotes	act
T3042	727-729	TO	denotes	to
T3041	722-726	JJ	denotes	able
T3040	719-721	VB	denotes	be
T3039	716-718	TO	denotes	to
T3038	707-715	VBN	denotes	reported
T3037	702-706	VBN	denotes	been
T3036	698-701	VBZ	denotes	has
T3035	693-697	NNP	denotes	Sox6
T3034	691-692	.	denotes	.
T3033	682-691	NNS	denotes	complexes
T3032	669-681	NN	denotes	multiprotein
T2967	289-294	VB	denotes	cause
T2966	285-288	CC	denotes	and
T2965	281-284	NNP	denotes	DNA
T2964	278-280	IN	denotes	of
T2963	271-277	NN	denotes	groove
T2962	265-270	JJ	denotes	minor
T2961	261-264	DT	denotes	the
T2960	258-260	TO	denotes	to
T2959	253-257	NN	denotes	bind
T2958	245-252	NNS	denotes	factors
T2957	231-244	NN	denotes	transcription
T2956	227-230	NNP	denotes	Sox
T2955	225-226	.	denotes	.
T2954	224-225	NNP	denotes	]
T2953	223-224	CD	denotes	1
T2952	222-223	NN	denotes	[
T2951	214-221	JJ	denotes	binding
T2950	210-213	CC	denotes	and
T2949	198-209	NN	denotes	recognition
T2948	194-197	NNP	denotes	DNA
T2947	191-193	IN	denotes	in
T2946	182-190	VBN	denotes	involved
T2945	176-181	NNS	denotes	acids
T2944	170-175	JJ	denotes	amino
T2943	167-169	CD	denotes	79
T2942	164-166	IN	denotes	of
T2941	153-163	VBG	denotes	consisting
T2940	151-152	,	denotes	,
T2939	145-151	NN	denotes	domain
T2938	143-144	-RRB-	denotes	)
T2937	140-143	NNP	denotes	HMG
T2936	139-140	-LRB-	denotes	(
T2935	133-138	NN	denotes	group
T2934	124-132	NN	denotes	mobility
T2933	119-123	JJ	denotes	high
T2932	109-118	JJ	denotes	conserved
T2931	105-108	DT	denotes	the
T2930	102-104	IN	denotes	by
T2929	88-101	VBN	denotes	characterized
T2928	81-87	NN	denotes	family
T2927	74-80	NN	denotes	factor
T2926	60-73	NN	denotes	transcription
T3751	4582-4584	CD	denotes	11
T3750	4580-4581	CD	denotes	8
T3749	4579-4580	NN	denotes	[
T3748	4572-4578	NN	denotes	system
T3747	4564-4571	JJ	denotes	nervous
T3746	4556-4563	JJ	denotes	central
T3745	4552-4555	DT	denotes	the
T3744	4549-4551	IN	denotes	of
T3743	4537-4548	NN	denotes	development
T3742	4533-4536	DT	denotes	the
T3741	4530-4532	IN	denotes	in
T3740	4525-4529	NN	denotes	role
T3739	4515-4524	JJ	denotes	important
T3738	4512-4514	DT	denotes	an
T3737	4504-4511	VBG	denotes	playing
T3736	4501-4503	TO	denotes	to
T3735	4492-4500	NN	denotes	addition
T3734	4489-4491	IN	denotes	In
T3733	4487-4488	.	denotes	.
T3732	4479-4487	NNS	denotes	proteins
T3731	4467-4478	VBG	denotes	transacting
T3730	4463-4466	CC	denotes	and
T3729	4454-4462	NNS	denotes	elements
T3728	4450-4453	NN	denotes	cis
T3727	4441-4449	JJ	denotes	multiple
T3726	4438-4440	IN	denotes	of
T3725	4430-4437	NN	denotes	network
T3724	4418-4429	JJ	denotes	complicated
T3723	4416-4417	DT	denotes	a
T3722	4407-4415	VBZ	denotes	involves
T3721	4402-4406	NN	denotes	gene
T3720	4400-4401	NN	denotes	ɛ
T3719	4396-4399	DT	denotes	the
T3718	4393-4395	IN	denotes	of
T3717	4383-4392	NN	denotes	silencing
T3716	4379-4382	DT	denotes	the
T3715	4374-4378	IN	denotes	that
T3714	4366-4373	VBZ	denotes	appears
T3713	4363-4365	PRP	denotes	it
T3712	4361-4362	,	denotes	,
T3711	4357-4361	RB	denotes	Thus
T3710	4355-4356	.	denotes	.
T3709	4354-4355	NNP	denotes	]
T3708	4352-4354	CD	denotes	27
T3707	4351-4352	NNP	denotes	[
T3706	4341-4350	VBG	denotes	silencing
T3705	4339-4340	NN	denotes	ɛ
T3704	4330-4338	VB	denotes	regulate
T3703	4327-4329	TO	denotes	to
T3702	4325-4326	-RRB-	denotes	)
T3701	4316-4325	NNS	denotes	complexes
T3700	4308-4315	NN	denotes	protein
T3699	4305-4307	IN	denotes	of
T3698	4300-4304	NN	denotes	part
T3697	4297-4299	IN	denotes	as
T3696	4296-4297	-LRB-	denotes	(
T3695	4287-4295	NNS	denotes	elements
T3694	4283-4286	NNP	denotes	DNA
T3693	4277-4282	DT	denotes	these
T3692	4274-4276	TO	denotes	to
T3691	4269-4273	NN	denotes	bind
T3690	4260-4268	RB	denotes	directly
T3283	1992-2002	NNS	denotes	phenotypes
T3282	1986-1991	JJ	denotes	other
T3281	1982-1985	DT	denotes	all
T3280	1979-1981	IN	denotes	in
T3279	1968-1978	VBN	denotes	implicated
T3278	1965-1967	VBZ	denotes	is
T3277	1958-1964	NN	denotes	factor
T3276	1944-1957	NN	denotes	transcription
T3275	1939-1943	NNP	denotes	Sox6
T3274	1935-1938	DT	denotes	the
T3273	1933-1934	,	denotes	,
T3272	1932-1933	NNP	denotes	]
T3271	1930-1932	CD	denotes	16
T3270	1929-1930	NNP	denotes	[
T3269	1916-1928	NN	denotes	pigmentation
T3268	1913-1915	IN	denotes	in
T3267	1906-1912	RB	denotes	solely
T3266	1896-1905	NNS	denotes	functions
T3265	1891-1895	NN	denotes	gene
T3264	1889-1890	NN	denotes	p
T3263	1885-1888	DT	denotes	the
T3262	1877-1884	IN	denotes	Because
T3261	1875-1876	.	denotes	.
T3260	1874-1875	NNP	denotes	]
T3259	1872-1874	CD	denotes	14
T3258	1871-1872	NNP	denotes	[
T3257	1869-1870	-RRB-	denotes	)
T3256	1858-1869	NNS	denotes	breakpoints
T3255	1846-1857	JJ	denotes	chromosomal
T3254	1842-1845	DT	denotes	the
T3253	1839-1841	IN	denotes	of
T3252	1827-1838	NNS	denotes	nucleotides
T3251	1820-1826	CD	denotes	50,000
T3250	1813-1819	IN	denotes	within
T3249	1808-1812	NN	denotes	gene
T3248	1802-1807	JJ	denotes	other
T3031	661-668	VBN	denotes	defined
T3030	650-660	RB	denotes	sterically
T3029	648-649	,	denotes	,
T3028	642-648	JJ	denotes	active
T3027	629-641	RB	denotes	biologically
T3026	624-628	IN	denotes	into
T3025	616-623	NNS	denotes	factors
T3024	602-615	NN	denotes	transcription
T3023	592-601	JJ	denotes	DNA-bound
T3022	586-591	JJ	denotes	other
T3021	575-585	VBG	denotes	assembling
T3020	571-574	CC	denotes	and
T3019	561-570	NN	denotes	structure
T3018	551-560	NN	denotes	chromatin
T3017	545-550	JJ	denotes	local
T3016	534-544	VBG	denotes	organizing
T3015	531-533	IN	denotes	by
T3014	522-530	NNS	denotes	proteins
T3013	508-521	JJ	denotes	architectural
T3012	505-507	IN	denotes	as
T3011	496-504	NN	denotes	function
T3010	490-495	PRP$	denotes	their
T3009	487-489	IN	denotes	of
T3008	482-486	NN	denotes	part
T3007	474-481	VB	denotes	perform
T3006	470-473	MD	denotes	may
T3005	461-469	NNS	denotes	proteins
T3004	457-460	NNP	denotes	Sox
T3003	455-456	,	denotes	,
T3002	446-455	RB	denotes	Therefore
T3001	444-445	.	denotes	.
T3000	443-444	NNP	denotes	]
T2999	442-443	CD	denotes	4
T2998	441-442	NNP	denotes	[
T2997	437-440	NNP	denotes	DNA
T2996	434-436	IN	denotes	of
T2995	427-433	NN	denotes	groove
T2994	421-426	JJ	denotes	major
T2993	417-420	DT	denotes	the
T2992	410-416	VBP	denotes	target
T2991	402-409	NNS	denotes	factors
T2990	388-401	NN	denotes	transcription
T2989	382-387	JJ	denotes	other
T2988	377-381	RBS	denotes	most
T2987	371-376	IN	denotes	while
T2986	369-370	,	denotes	,
T2985	368-369	NNP	denotes	]
T2984	365-368	CD	denotes	2,3
T2983	364-365	NNP	denotes	[
T2982	356-363	NNS	denotes	changes
T2981	341-355	JJ	denotes	conformational
T2980	335-340	JJ	denotes	local
T2979	332-334	TO	denotes	to
T2978	326-331	VBZ	denotes	leads
T2977	321-325	WDT	denotes	that
T2976	317-320	NN	denotes	DNA
T2975	313-316	DT	denotes	the
T2974	310-312	IN	denotes	of
T2973	305-309	VB	denotes	bend
T2972	303-304	NN	denotes	°
T2971	301-303	CD	denotes	85
T2970	299-300	NN	denotes	°
T2969	297-299	CD	denotes	70
T2968	295-296	DT	denotes	a
T2925	56-59	NNPS	denotes	Sox
T2924	52-55	DT	denotes	the
T2923	49-51	IN	denotes	of
T2922	42-48	NN	denotes	member
T2921	40-41	DT	denotes	a
T2920	37-39	VBZ	denotes	is
T2919	35-36	-RRB-	denotes	)
T2918	31-35	NNP	denotes	Sox6
T2917	30-31	-LRB-	denotes	(
T2916	26-29	NN	denotes	box
T2915	22-25	NNP	denotes	HMG
T2914	17-21	NN	denotes	type
T2913	13-16	NNP	denotes	Sry
R1907	T2913	T2916	compound	Sry,box
R1909	T2914	T2916	compound	type,box
R1914	T2915	T2916	compound	HMG,box
R1918	T2916	T2920	nsubj	box,is
R1921	T2917	T2918	punct	(,Sox6
R1922	T2918	T2916	appos	Sox6,box
R1923	T2919	T2916	punct	),box
R1924	T2920	T2920	ROOT	is,is
R1925	T2921	T2922	det	a,member
R1926	T2922	T2920	attr	member,is
R1927	T2926	T2927	compound	transcription,factor
R1928	T2923	T2922	prep	of,member
R1929	T2927	T2928	compound	factor,family
R1930	T2928	T2923	pobj	family,of
R1931	T2929	T2922	acl	characterized,member
R1932	T2924	T2928	det	the,family
R1933	T2930	T2929	agent	by,characterized
R1934	T2931	T2935	det	the,group
R1935	T2925	T2928	compound	Sox,family
R1936	T2932	T2935	amod	conserved,group
R1937	T2933	T2935	amod	high,group
R1938	T2934	T2935	compound	mobility,group
R1939	T3023	T3025	amod	DNA-bound,factors
R1940	T2935	T2930	pobj	group,by
R1941	T2936	T2937	punct	(,HMG
R1942	T2937	T2935	appos	HMG,group
R1943	T2938	T2937	punct	),HMG
R1944	T3024	T3025	compound	transcription,factors
R1945	T2939	T2935	conj	domain,group
R1946	T2940	T2935	punct	",",group
R1947	T2941	T2935	acl	consisting,group
R1948	T3025	T3021	dobj	factors,assembling
R1949	T2942	T2941	prep	of,consisting
R1950	T2943	T2945	nummod	79,acids
R1951	T3026	T3021	prep	into,assembling
R1952	T2944	T2945	compound	amino,acids
R1953	T2945	T2942	pobj	acids,of
R1954	T2946	T2945	acl	involved,acids
R1955	T3027	T3028	advmod	biologically,active
R1956	T2947	T2946	prep	in,involved
R1957	T2948	T2949	compound	DNA,recognition
R1958	T2949	T2947	pobj	recognition,in
R1959	T3028	T3033	amod	active,complexes
R1960	T2950	T2949	cc	and,recognition
R1961	T2951	T2952	amod	binding,[
R1962	T2952	T2949	conj	[,recognition
R1963	T2953	T2954	nummod	1,]
R1964	T3029	T3033	punct	",",complexes
R1965	T2954	T2952	appos	],[
R1966	T2955	T2920	punct	.,is
R1967	T3030	T3031	advmod	sterically,defined
R1968	T2956	T2959	nsubj	Sox,bind
R1969	T2957	T2958	compound	transcription,factors
R1970	T2958	T2959	nsubj	factors,bind
R1971	T3031	T3033	amod	defined,complexes
R1972	T2959	T2959	ROOT	bind,bind
R1973	T2960	T2959	prep	to,bind
R1974	T3032	T3033	compound	multiprotein,complexes
R1975	T2961	T2963	det	the,groove
R1976	T2962	T2963	amod	minor,groove
R1977	T3033	T3026	pobj	complexes,into
R1978	T2963	T2960	pobj	groove,to
R1979	T2964	T2963	prep	of,groove
R1980	T2965	T2964	pobj	DNA,of
R1981	T2966	T2959	cc	and,bind
R1982	T2967	T2959	conj	cause,bind
R1983	T2968	T2970	det	a,°
R1984	T3034	T3007	punct	.,perform
R1985	T2969	T2970	nummod	70,°
R1986	T2970	T2967	dobj	°,cause
R1987	T2971	T2973	nummod	85,bend
R1988	T3035	T3038	nsubjpass	Sox6,reported
R1989	T2972	T2973	compound	°,bend
R1990	T2973	T2970	appos	bend,°
R1991	T2974	T2973	prep	of,bend
R1992	T3036	T3038	aux	has,reported
R1993	T2975	T2976	det	the,DNA
R1994	T2976	T2974	pobj	DNA,of
R1995	T2977	T2978	nsubj	that,leads
R1996	T3037	T3038	auxpass	been,reported
R1997	T2978	T2976	relcl	leads,DNA
R1998	T2979	T2978	prep	to,leads
R1999	T2980	T2982	amod	local,changes
R2000	T2981	T2982	amod	conformational,changes
R2001	T3038	T3038	ROOT	reported,reported
R2002	T2982	T2979	pobj	changes,to
R2003	T2983	T2985	compound	[,]
R2004	T3039	T3040	aux	to,be
R2005	T2984	T2985	compound	"2,3",]
R2006	T2985	T2982	appos	],changes
R2007	T2986	T2973	punct	",",bend
R2008	T3040	T3038	xcomp	be,reported
R2009	T2987	T2992	mark	while,target
R2010	T2988	T2991	amod	most,factors
R2011	T2989	T2991	amod	other,factors
R2012	T3041	T3040	acomp	able,be
R2013	T2990	T2991	compound	transcription,factors
R2014	T2991	T2992	nsubj	factors,target
R2015	T2992	T2973	advcl	target,bend
R2016	T2993	T2995	det	the,groove
R2017	T2994	T2995	amod	major,groove
R2018	T2995	T2992	dobj	groove,target
R2019	T2996	T2995	prep	of,groove
R2020	T2997	T3000	compound	DNA,]
R2021	T3042	T3043	aux	to,act
R2022	T2998	T3000	nmod	[,]
R2023	T2999	T3000	nummod	4,]
R2024	T3000	T2996	pobj	],of
R2025	T3043	T3041	xcomp	act,able
R2026	T3001	T2959	punct	.,bind
R2027	T3002	T3007	advmod	Therefore,perform
R2028	T3044	T3043	prep	as,act
R2029	T3003	T3007	punct	",",perform
R2030	T3004	T3005	compound	Sox,proteins
R2031	T3005	T3007	nsubj	proteins,perform
R2032	T3045	T3047	preconj	either,activator
R2033	T3006	T3007	aux	may,perform
R2034	T3007	T3007	ROOT	perform,perform
R2035	T3008	T3007	dobj	part,perform
R2036	T3046	T3047	det	an,activator
R2037	T3009	T3008	prep	of,part
R2038	T3010	T3011	poss	their,function
R2039	T3047	T3044	pobj	activator,as
R2040	T3011	T3009	pobj	function,of
R2041	T3012	T3007	prep	as,perform
R2042	T3013	T3014	amod	architectural,proteins
R2043	T3048	T3047	cc	or,activator
R2044	T3014	T3012	pobj	proteins,as
R2045	T3015	T3007	prep	by,perform
R2046	T3016	T3015	pcomp	organizing,by
R2047	T3049	T3050	det	a,repressor
R2048	T3017	T3019	amod	local,structure
R2049	T3018	T3019	compound	chromatin,structure
R2050	T3050	T3047	conj	repressor,activator
R2051	T3019	T3016	dobj	structure,organizing
R2052	T3020	T3016	cc	and,organizing
R2053	T3021	T3016	conj	assembling,organizing
R2054	T3051	T3050	punct	",",repressor
R2055	T3022	T3025	amod	other,factors
R2056	T3052	T3043	prep	depending,act
R2057	T3053	T3052	prep	on,depending
R2058	T3054	T3055	poss	its,interactors
R2059	T3055	T3053	pobj	interactors,on
R2060	T3056	T3055	cc	and,interactors
R2061	T3120	T3118	punct	",",restored
R2062	T3057	T3060	poss	its,context
R2063	T3121	T3118	advcl	indicating,restored
R2064	T3122	T3123	amod	functional,overlap
R2065	T3123	T3121	dobj	overlap,indicating
R2066	T3124	T3123	prep	of,overlap
R2067	T3125	T3126	det	these,proteins
R2068	T3058	T3059	compound	target,promoter
R2069	T3126	T3124	pobj	proteins,of
R2070	T3127	T3123	conj	[,overlap
R2071	T3128	T3129	nummod	7,]
R2072	T3059	T3060	compound	promoter,context
R2073	T3129	T3127	dobj	],[
R2074	T3130	T3118	punct	.,restored
R2075	T3131	T3131	ROOT	Regardless,Regardless
R2076	T3060	T3052	conj	context,depending
R2077	T3132	T3131	prep	of,Regardless
R2078	T3133	T3144	advmod	how,demonstrated
R2079	T3134	T3135	amod	Sox6,functions
R2080	T3061	T3063	compound	[,]
R2081	T3135	T3144	nsubj	functions,demonstrated
R2082	T3136	T3135	prep	in,functions
R2083	T3062	T3063	compound	"5,6",]
R2084	T3137	T3136	pcomp	regulating,in
R2085	T3138	T3139	compound	gene,expression
R2086	T3063	T3060	appos	],context
R2087	T3139	T3137	dobj	expression,regulating
R2088	T3140	T3144	punct	",",demonstrated
R2089	T3141	T3142	amod	previous,studies
R2090	T3064	T3038	punct	.,reported
R2091	T3142	T3144	nsubj	studies,demonstrated
R2092	T3143	T3144	aux	have,demonstrated
R2093	T3144	T3132	pcomp	demonstrated,of
R2094	T3065	T3071	advmod	Intriguingly,shown
R2095	T3145	T3147	mark	that,is
R2096	T3146	T3147	nsubj	Sox6,is
R2097	T3147	T3144	ccomp	is,demonstrated
R2098	T3066	T3071	punct	",",shown
R2099	T3148	T3151	det	an,molecule
R2100	T3149	T3151	amod	important,molecule
R2101	T3150	T3151	amod	regulatory,molecule
R2102	T3067	T3071	nsubj	Sox6,shown
R2103	T3151	T3147	attr	molecule,is
R2104	T3152	T3153	nsubj	that,plays
R2105	T3068	T3071	aux	has,shown
R2106	T3153	T3151	relcl	plays,molecule
R2107	T3154	T3155	det	a,role
R2108	T3155	T3153	dobj	role,plays
R2109	T3156	T3155	prep	in,role
R2110	T3069	T3071	advmod	also,shown
R2111	T3157	T3158	det	the,development
R2112	T3158	T3156	pobj	development,in
R2113	T3159	T3158	prep	of,development
R2114	T3160	T3163	det	the,system
R2115	T3161	T3163	amod	central,system
R2116	T3162	T3163	amod	nervous,system
R2117	T3070	T3071	auxpass	been,shown
R2118	T3163	T3159	pobj	system,of
R2119	T3164	T3172	nmod	[,]
R2120	T3165	T3164	nummod	8,[
R2121	T3071	T3071	ROOT	shown,shown
R2122	T3166	T3167	nummod	11,]
R2123	T3167	T3164	appos	],[
R2124	T3168	T3169	punct	",",cartilage
R2125	T3169	T3164	conj	cartilage,[
R2126	T3072	T3073	aux	to,act
R2127	T3170	T3172	compound	[,]
R2128	T3171	T3172	compound	"6,12,13",]
R2129	T3172	T3153	npadvmod	],plays
R2130	T3073	T3071	xcomp	act,shown
R2131	T3173	T3172	punct	",",]
R2132	T3174	T3172	cc	and,]
R2133	T3074	T3073	prep	as,act
R2134	T3175	T3178	compound	muscle,]
R2135	T3176	T3178	compound	[,]
R2136	T3075	T3078	det	a,factor
R2137	T3177	T3178	compound	"14,15",]
R2138	T3178	T3172	conj	],]
R2139	T3179	T3131	punct	.,Regardless
R2140	T3076	T3078	amod	general,factor
R2141	T3180	T3183	det	A,mouse
R2142	T3181	T3183	amod	Sox6-null,mouse
R2143	T3182	T3183	amod	mutant,mouse
R2144	T3077	T3078	compound	splicing,factor
R2145	T3183	T3190	nsubjpass	mouse,identified
R2146	T3184	T3185	punct	(,p100H
R2147	T3185	T3183	appos	p100H,mouse
R2148	T3078	T3074	pobj	factor,as
R2149	T3186	T3185	punct	),p100H
R2150	T3187	T3190	aux	has,identified
R2151	T3188	T3190	advmod	previously,identified
R2152	T3079	T3080	nsubj	that,participates
R2153	T3080	T3078	relcl	participates,factor
R2154	T3189	T3190	auxpass	been,identified
R2155	T3190	T3190	ROOT	identified,identified
R2156	T3191	T3190	prep	in,identified
R2157	T3081	T3080	prep	in,participates
R2158	T3192	T3193	poss	our,laboratory
R2159	T3193	T3191	pobj	laboratory,in
R2160	T3082	T3084	amod	pre-mRNA,[
R2161	T3194	T3196	nmod	[,]
R2162	T3195	T3196	nummod	14,]
R2163	T3196	T3190	dobj	],identified
R2164	T3197	T3190	punct	.,identified
R2165	T3198	T3199	compound	Mice,homozygous
R2166	T3199	T3206	nsubj	homozygous,develop
R2167	T3083	T3084	compound	splicing,[
R2168	T3200	T3199	prep	for,homozygous
R2169	T3201	T3202	amod	p100H,show
R2170	T3202	T3200	pobj	show,for
R2171	T3084	T3086	nmod	[,]
R2172	T3203	T3204	amod	delayed,growth
R2173	T3204	T3202	dobj	growth,show
R2174	T3085	T3086	nummod	7,]
R2175	T3205	T3202	punct	",",show
R2176	T3206	T3206	ROOT	develop,develop
R2177	T3207	T3211	nmod	myopathy,block
R2178	T3086	T3081	pobj	],in
R2179	T3208	T3207	cc	and,myopathy
R2180	T3209	T3207	conj	arterioventricular,myopathy
R2181	T3210	T3211	compound	heart,block
R2182	T3211	T3206	dobj	block,develop
R2183	T3087	T3071	punct	.,shown
R2184	T3212	T3206	punct	",",develop
R2185	T3213	T3206	cc	and,develop
R2186	T3214	T3206	conj	die,develop
R2187	T3088	T3095	nsubj	Depletion,blocked
R2188	T3215	T3214	prep	within,die
R2189	T3216	T3217	nummod	2,wk
R2190	T3089	T3088	prep	of,Depletion
R2191	T3090	T3089	pobj	Sox6,of
R2192	T3091	T3090	prep	in,Sox6
R2193	T3217	T3215	pobj	wk,within
R2194	T3218	T3214	prep	after,die
R2195	T3219	T3218	pobj	birth,after
R2196	T3092	T3093	compound	HeLa,cell
R2197	T3220	T3222	nmod	[,]
R2198	T3221	T3222	nummod	14,]
R2199	T3093	T3094	compound	cell,extracts
R2200	T3222	T3214	conj	],die
R2201	T3223	T3206	punct	.,develop
R2202	T3224	T3227	det	The,allele
R2203	T3094	T3095	nsubj	extracts,blocked
R2204	T3225	T3227	amod	p100H,allele
R2205	T3226	T3227	amod	mutant,allele
R2206	T3227	T3229	nsubjpass	allele,associated
R2207	T3095	T3095	ROOT	blocked,blocked
R2208	T3228	T3229	auxpass	is,associated
R2209	T3229	T3229	ROOT	associated,associated
R2210	T3096	T3095	dobj	splicing,blocked
R2211	T3230	T3229	prep	with,associated
R2212	T3231	T3234	det	a,inversion
R2213	T3232	T3234	nmod	Chromosome,inversion
R2214	T3233	T3232	nummod	7,Chromosome
R2215	T3234	T3230	pobj	inversion,with
R2216	T3235	T3236	nsubj	that,disrupts
R2217	T3097	T3096	prep	of,splicing
R2218	T3236	T3234	relcl	disrupts,inversion
R2219	T3237	T3240	preconj	both,gene
R2220	T3238	T3240	det	the,gene
R2221	T3098	T3099	amod	multiple,substrates
R2222	T3239	T3240	compound	p,gene
R2223	T3240	T3236	dobj	gene,disrupts
R2224	T3241	T3240	cc	and,gene
R2225	T3099	T3097	pobj	substrates,of
R2226	T3242	T3244	det	the,gene
R2227	T3243	T3244	compound	Sox6,gene
R2228	T3244	T3240	conj	gene,gene
R2229	T3100	T3095	punct	",",blocked
R2230	T3245	T3244	punct	(,gene
R2231	T3246	T3244	cc	and,gene
R2232	T3247	T3249	det	no,gene
R2233	T3101	T3095	cc	and,blocked
R2234	T3248	T3249	amod	other,gene
R2235	T3249	T3244	conj	gene,gene
R2236	T3250	T3249	prep	within,gene
R2237	T3102	T3095	conj	expression,blocked
R2238	T3251	T3252	nummod	"50,000",nucleotides
R2239	T3252	T3250	pobj	nucleotides,within
R2240	T3103	T3102	prep	of,expression
R2241	T3253	T3252	prep	of,nucleotides
R2242	T3254	T3256	det	the,breakpoints
R2243	T3255	T3256	amod	chromosomal,breakpoints
R2244	T3104	T3106	det	the,domain
R2245	T3256	T3253	pobj	breakpoints,of
R2246	T3257	T3229	punct	),associated
R2247	T3105	T3106	compound	HMG,domain
R2248	T3258	T3260	nmod	[,]
R2249	T3259	T3260	nummod	14,]
R2250	T3260	T3260	ROOT	],]
R2251	T3261	T3260	punct	.,]
R2252	T3106	T3103	pobj	domain,of
R2253	T3262	T3279	mark	Because,implicated
R2254	T3263	T3266	det	the,functions
R2255	T3107	T3106	prep	of,domain
R2256	T3264	T3265	compound	p,gene
R2257	T3265	T3266	compound	gene,functions
R2258	T3266	T3279	advcl	functions,implicated
R2259	T3108	T3118	preconj	either,restored
R2260	T3267	T3268	advmod	solely,in
R2261	T3268	T3266	prep	in,functions
R2262	T3109	T3118	nsubj	Sox6,restored
R2263	T3269	T3268	pobj	pigmentation,in
R2264	T3110	T3109	punct	",",Sox6
R2265	T3270	T3272	nmod	[,]
R2266	T3271	T3272	nummod	16,]
R2267	T3272	T3266	appos	],functions
R2268	T3273	T3279	punct	",",implicated
R2269	T3274	T3277	det	the,factor
R2270	T3111	T3109	conj	Sox9,Sox6
R2271	T3275	T3277	compound	Sox6,factor
R2272	T3276	T3277	compound	transcription,factor
R2273	T3112	T3111	punct	",",Sox9
R2274	T3277	T3279	nsubjpass	factor,implicated
R2275	T3278	T3279	auxpass	is,implicated
R2276	T3279	T3279	ROOT	implicated,implicated
R2277	T3280	T3279	prep	in,implicated
R2278	T3113	T3111	cc	or,Sox9
R2279	T3281	T3283	det	all,phenotypes
R2280	T3282	T3283	amod	other,phenotypes
R2281	T3283	T3280	pobj	phenotypes,in
R2282	T3114	T3111	conj	Sry,Sox9
R2283	T3284	T3279	punct	.,implicated
R2284	T3285	T3322	prep	Among,are
R2285	T3286	T3289	det	the,proteins
R2286	T3115	T3109	prep	in,Sox6
R2287	T3287	T3289	compound	HMG,proteins
R2288	T3288	T3289	compound	box,proteins
R2289	T3289	T3285	pobj	proteins,Among
R2290	T3116	T3117	det	the,extracts
R2291	T3290	T3291	advmod	distantly,related
R2292	T3291	T3289	acl	related,proteins
R2293	T3292	T3291	prep	to,related
R2294	T3117	T3115	pobj	extracts,in
R2295	T3293	T3292	pobj	Sry,to
R2296	T3294	T3293	punct	(,Sry
R2297	T3295	T3297	det	the,member
R2298	T3118	T3095	conj	restored,blocked
R2299	T3296	T3297	amod	first,member
R2300	T3297	T3293	appos	member,Sry
R2301	T3298	T3297	acl	identified,member
R2302	T3119	T3118	dobj	splicing,restored
R2303	T3299	T3298	prep	of,identified
R2304	T3300	T3304	det	the,family
R2305	T3314	T3308	conj	bend,bind
R2306	T3301	T3303	compound	Sox,factor
R2307	T3302	T3303	compound	transcription,factor
R2308	T3303	T3304	compound	factor,family
R2309	T3304	T3299	pobj	family,of
R2310	T3315	T3314	dobj	DNA,bend
R2311	T3305	T3293	punct	),Sry
R2312	T3306	T3308	nsubj	that,bind
R2313	T3307	T3308	advmod	similarly,bind
R2314	T3316	T3314	punct	",",bend
R2315	T3308	T3289	relcl	bind,proteins
R2316	T3309	T3308	prep	to,bind
R2317	T3310	T3312	det	the,groove
R2318	T3311	T3312	amod	minor,groove
R2319	T3312	T3309	pobj	groove,to
R2320	T3313	T3308	cc	and,bind
R2321	T3317	T3314	cc	but,bend
R2322	T3318	T3308	prep	without,bind
R2323	T3319	T3320	compound	sequence,specificity
R2324	T3411	T3401	cc	and,are
R2325	T3320	T3318	pobj	specificity,without
R2326	T3412	T3401	conj	function,are
R2327	T3413	T3415	nmod	[,]
R2328	T3321	T3322	punct	",",are
R2329	T3414	T3415	nummod	22,]
R2330	T3415	T3412	dobj	],function
R2331	T3416	T3401	punct	.,are
R2332	T3322	T3322	ROOT	are,are
R2333	T3417	T3418	amod	High-level,expression
R2334	T3418	T3422	nsubj	expression,requires
R2335	T3419	T3418	prep	of,expression
R2336	T3323	T3329	det	the,proteins
R2337	T3420	T3421	det	these,genes
R2338	T3421	T3419	pobj	genes,of
R2339	T3422	T3422	ROOT	requires,requires
R2340	T3324	T3325	nsubj	ubiquitously,expressed
R2341	T3423	T3425	det	a,element
R2342	T3424	T3425	amod	regulatory,element
R2343	T3325	T3329	amod	expressed,proteins
R2344	T3425	T3422	dobj	element,requires
R2345	T3426	T3425	punct	",",element
R2346	T3326	T3329	nmod	HMG1,proteins
R2347	T3427	T3430	det	the,region
R2348	T3428	T3429	compound	locus,control
R2349	T3327	T3326	cc	and,HMG1
R2350	T3429	T3430	compound	control,region
R2351	T3430	T3425	appos	region,element
R2352	T3328	T3326	conj	HMG2,HMG1
R2353	T3431	T3433	nsubjpass	that,characterized
R2354	T3432	T3433	auxpass	is,characterized
R2355	T3433	T3430	relcl	characterized,region
R2356	T3329	T3322	attr	proteins,are
R2357	T3330	T3332	nmod	[,]
R2358	T3434	T3433	agent	by,characterized
R2359	T3331	T3332	nummod	17,]
R2360	T3435	T3436	det	a,set
R2361	T3436	T3434	pobj	set,by
R2362	T3332	T3329	appos	],proteins
R2363	T3437	T3436	prep	of,set
R2364	T3438	T3440	amod	nuclease,sites
R2365	T3439	T3440	amod	hypersensitive,sites
R2366	T3440	T3437	pobj	sites,of
R2367	T3441	T3436	acl	spread,set
R2368	T3442	T3441	prep	over,spread
R2369	T3333	T3322	punct	.,are
R2370	T3443	T3444	nummod	25,kb
R2371	T3444	T3445	npadvmod	kb,located
R2372	T3445	T3436	acl	located,set
R2373	T3334	T3345	nsubj	Modulation,mediate
R2374	T3446	T3447	nummod	5,′
R2375	T3447	T3445	dobj	′,located
R2376	T3448	T3447	prep	of,′
R2377	T3335	T3334	prep	of,Modulation
R2378	T3449	T3451	det	the,gene
R2379	T3450	T3451	amod	ɛy,gene
R2380	T3451	T3448	pobj	gene,of
R2381	T3336	T3337	compound	DNA,structure
R2382	T3452	T3447	conj	[,′
R2383	T3453	T3454	nummod	23,]
R2384	T3454	T3447	conj	],′
R2385	T3337	T3335	pobj	structure,of
R2386	T3455	T3422	punct	.,requires
R2387	T3456	T3458	det	The,genes
R2388	T3457	T3458	amod	β-globin,genes
R2389	T3338	T3334	agent	by,Modulation
R2390	T3458	T3460	nsubjpass	genes,expressed
R2391	T3459	T3460	auxpass	are,expressed
R2392	T3460	T3460	ROOT	expressed,expressed
R2393	T3339	T3343	det	these,proteins
R2394	T3461	T3460	prep	in,expressed
R2395	T3462	T3463	det	a,tissue
R2396	T3463	T3461	pobj	tissue,in
R2397	T3340	T3339	cc	and,these
R2398	T3464	T3460	punct	-,expressed
R2399	T3465	T3460	cc	and,expressed
R2400	T3466	T3467	amod	development-specific,fashion
R2401	T3341	T3343	amod	other,proteins
R2402	T3467	T3460	conj	fashion,expressed
R2403	T3468	T3460	punct	.,expressed
R2404	T3469	T3473	prep	In,originates
R2405	T3342	T3343	compound	HMG,proteins
R2406	T3470	T3469	pobj	mice,In
R2407	T3471	T3472	punct	",",erythropoiesis
R2408	T3472	T3473	nsubj	erythropoiesis,originates
R2409	T3343	T3338	pobj	proteins,by
R2410	T3473	T3473	ROOT	originates,originates
R2411	T3474	T3473	prep	in,originates
R2412	T3344	T3345	aux	can,mediate
R2413	T3475	T3478	det	the,sac
R2414	T3476	T3477	amod	embryonic,yolk
R2415	T3477	T3478	compound	yolk,sac
R2416	T3478	T3474	pobj	sac,in
R2417	T3479	T3483	advmod	where,express
R2418	T3480	T3482	amod	primitive,cells
R2419	T3345	T3345	ROOT	mediate,mediate
R2420	T3481	T3482	amod	erythroid,cells
R2421	T3482	T3483	nsubj	cells,express
R2422	T3483	T3478	relcl	express,sac
R2423	T3346	T3348	amod	long-range,function
R2424	T3484	T3483	dobj	ɛy,express
R2425	T3485	T3484	cc	and,ɛy
R2426	T3486	T3487	amod	βh-1,globins
R2427	T3487	T3484	conj	globins,ɛy
R2428	T3347	T3348	compound	enhancer,function
R2429	T3488	T3490	nmod	[,]
R2430	T3489	T3490	nummod	22,]
R2431	T3490	T3490	ROOT	],]
R2432	T3348	T3345	dobj	function,mediate
R2433	T3491	T3490	punct	.,]
R2434	T3492	T3523	prep	At,]
R2435	T3493	T3502	nummod	11.5,shifts
R2436	T3349	T3348	prep	on,function
R2437	T3494	T3502	nmod	d,shifts
R2438	T3495	T3496	compound	post,coitus
R2439	T3350	T3351	det	both,DNA
R2440	T3496	T3502	dep	coitus,shifts
R2441	T3497	T3498	punct	(,dpc
R2442	T3498	T3496	parataxis	dpc,coitus
R2443	T3351	T3349	pobj	DNA,on
R2444	T3499	T3498	punct	),dpc
R2445	T3500	T3501	punct	",",erythropoiesis
R2446	T3501	T3502	compound	erythropoiesis,shifts
R2447	T3352	T3351	cc	and,DNA
R2448	T3502	T3492	pobj	shifts,At
R2449	T3503	T3502	prep	to,shifts
R2450	T3353	T3354	amod	chromatin-assembled,genes
R2451	T3504	T3506	det	the,liver
R2452	T3505	T3506	amod	fetal,liver
R2453	T3354	T3351	conj	genes,DNA
R2454	T3506	T3503	pobj	liver,to
R2455	T3355	T3345	prep	by,mediate
R2456	T3507	T3511	advmod	where,express
R2457	T3356	T3355	pcomp	bringing,by
R2458	T3357	T3356	advmod	together,bringing
R2459	T3508	T3510	amod	definitive,cells
R2460	T3358	T3359	amod	distant,regions
R2461	T3509	T3510	amod	erythroid,cells
R2462	T3510	T3511	nsubj	cells,express
R2463	T3359	T3356	dobj	regions,bringing
R2464	T3511	T3506	relcl	express,liver
R2465	T3512	T3514	compound	adult,globins
R2466	T3513	T3514	compound	β,globins
R2467	T3514	T3511	dobj	globins,express
R2468	T3515	T3514	punct	(,globins
R2469	T3360	T3359	prep	of,regions
R2470	T3516	T3517	advmod	β,major
R2471	T3517	T3514	amod	major,globins
R2472	T3518	T3517	cc	and,major
R2473	T3361	T3360	pobj	DNA,of
R2474	T3519	T3517	conj	minor,major
R2475	T3520	T3492	punct	),At
R2476	T3521	T3523	nmod	[,]
R2477	T3362	T3356	cc	and,bringing
R2478	T3522	T3523	nummod	22,]
R2479	T3523	T3523	ROOT	],]
R2480	T3363	T3364	amod	associated,factors
R2481	T3524	T3523	punct	.,]
R2482	T3525	T3527	det	The,gene
R2483	T3526	T3527	amod	ɛy,gene
R2484	T3364	T3356	dobj	factors,bringing
R2485	T3527	T3529	nsubjpass	gene,silenced
R2486	T3528	T3529	auxpass	is,silenced
R2487	T3365	T3345	punct	.,mediate
R2488	T3529	T3529	ROOT	silenced,silenced
R2489	T3530	T3529	prep	in,silenced
R2490	T3531	T3533	amod	definitive,cells
R2491	T3366	T3372	advmod	Specifically,shown
R2492	T3532	T3533	amod	erythroid,cells
R2493	T3533	T3530	pobj	cells,in
R2494	T3367	T3372	punct	",",shown
R2495	T3534	T3529	punct	.,silenced
R2496	T3535	T3536	det	The,mechanism
R2497	T3536	T3549	nsubj	mechanism,studied
R2498	T3368	T3369	compound	HMG,proteins
R2499	T3537	T3536	prep	of,mechanism
R2500	T3538	T3537	pcomp	silencing,of
R2501	T3539	T3538	prep	of,silencing
R2502	T3369	T3372	nsubjpass	proteins,shown
R2503	T3540	T3542	poss	its,counterpart
R2504	T3541	T3542	amod	human,counterpart
R2505	T3542	T3539	pobj	counterpart,of
R2506	T3370	T3372	aux	have,shown
R2507	T3543	T3542	punct	",",counterpart
R2508	T3544	T3545	compound	ɛ,globin
R2509	T3545	T3542	appos	globin,counterpart
R2510	T3371	T3372	auxpass	been,shown
R2511	T3546	T3549	punct	",",studied
R2512	T3547	T3549	aux	has,studied
R2513	T3372	T3372	ROOT	shown,shown
R2514	T3548	T3549	auxpass	been,studied
R2515	T3549	T3549	ROOT	studied,studied
R2516	T3550	T3549	advmod	extensively,studied
R2517	T3551	T3549	punct	.,studied
R2518	T3552	T3558	prep	In,activated
R2519	T3553	T3554	amod	definitive,erythropoiesis
R2520	T3554	T3552	pobj	erythropoiesis,In
R2521	T3373	T3374	aux	to,modulate
R2522	T3555	T3558	punct	",",activated
R2523	T3556	T3558	nsubjpass	ɛ,activated
R2524	T3374	T3372	xcomp	modulate,shown
R2525	T3557	T3558	auxpass	is,activated
R2526	T3558	T3558	ROOT	activated,activated
R2527	T3559	T3558	cc	and,activated
R2528	T3375	T3376	amod	β-globin,genes
R2529	T3560	T3558	conj	silenced,activated
R2530	T3561	T3564	advmod	autonomously,]
R2531	T3562	T3564	compound	[,]
R2532	T3376	T3374	dobj	genes,modulate
R2533	T3563	T3564	compound	"24,25",]
R2534	T3564	T3560	dobj	],silenced
R2535	T3377	T3374	npadvmod	[,modulate
R2536	T3565	T3560	punct	",",silenced
R2537	T3566	T3572	mark	although,appears
R2538	T3567	T3572	prep	in,appears
R2539	T3378	T3377	nummod	18,[
R2540	T3568	T3570	amod	primitive,ɛ
R2541	T3569	T3570	compound	erythropoiesis,ɛ
R2542	T3570	T3567	pobj	ɛ,in
R2543	T3379	T3380	nummod	21,]
R2544	T3571	T3572	advmod	also,appears
R2545	T3572	T3558	conj	appears,activated
R2546	T3380	T3377	appos	],[
R2547	T3573	T3575	aux	to,regulated
R2548	T3574	T3575	auxpass	be,regulated
R2549	T3575	T3572	xcomp	regulated,appears
R2550	T3381	T3372	punct	.,shown
R2551	T3576	T3575	advmod	competitively,regulated
R2552	T3577	T3579	nmod	[,]
R2553	T3382	T3385	det	The,genes
R2554	T3578	T3579	nummod	26,]
R2555	T3579	T3572	dep	],appears
R2556	T3580	T3572	punct	.,appears
R2557	T3383	T3385	compound	mouse,genes
R2558	T3581	T3582	det	The,γ-globin
R2559	T3582	T3588	nsubjpass	γ-globin,controlled
R2560	T3583	T3584	aux	to,adult
R2561	T3384	T3385	compound	β-globin,genes
R2562	T3385	T3395	nsubjpass	genes,clustered
R2563	T3584	T3582	acl	adult,γ-globin
R2564	T3585	T3586	compound	β-globin,switch
R2565	T3386	T3385	appos	ɛy,genes
R2566	T3586	T3588	nsubjpass	switch,controlled
R2567	T3587	T3588	auxpass	is,controlled
R2568	T3588	T3588	ROOT	controlled,controlled
R2569	T3589	T3588	agent	by,controlled
R2570	T3590	T3591	compound	promoter,competition
R2571	T3591	T3589	pobj	competition,by
R2572	T3387	T3386	punct	",",ɛy
R2573	T3592	T3591	prep	for,competition
R2574	T3593	T3597	det	the,]
R2575	T3388	T3386	appos	βh1,ɛy
R2576	T3594	T3595	compound	LCR,[
R2577	T3595	T3597	nmod	[,]
R2578	T3389	T3386	punct	",",ɛy
R2579	T3596	T3597	nummod	"24,25",]
R2580	T3597	T3592	pobj	],for
R2581	T3598	T3588	punct	.,controlled
R2582	T3599	T3601	predet	All,elements
R2583	T3390	T3386	conj	β-major,ɛy
R2584	T3600	T3601	det	the,elements
R2585	T3601	T3609	nsubj	elements,are
R2586	T3391	T3390	punct	",",β-major
R2587	T3602	T3601	amod	responsible,elements
R2588	T3603	T3602	prep	for,responsible
R2589	T3604	T3603	pcomp	silencing,for
R2590	T3392	T3390	cc	and,β-major
R2591	T3393	T3390	conj	β-minor,β-major
R2592	T3394	T3395	auxpass	are,clustered
R2593	T3605	T3608	det	the,gene
R2594	T3606	T3608	nmod	ɛ,gene
R2595	T3395	T3395	ROOT	clustered,clustered
R2596	T3607	T3608	compound	globin,gene
R2597	T3608	T3604	dobj	gene,silencing
R2598	T3396	T3395	prep	on,clustered
R2599	T3609	T3609	ROOT	are,are
R2600	T3610	T3609	prep	within,are
R2601	T3611	T3613	det	the,gene
R2602	T3397	T3396	pobj	Chromosome,on
R2603	T3612	T3613	compound	ɛ,gene
R2604	T3613	T3610	pobj	gene,within
R2605	T3614	T3610	cc	or,within
R2606	T3398	T3397	nummod	7,Chromosome
R2607	T3615	T3610	conj	in,within
R2608	T3616	T3617	amod	adjacent,sequences
R2609	T3399	T3395	cc	and,clustered
R2610	T3617	T3615	pobj	sequences,in
R2611	T3618	T3620	nmod	[,]
R2612	T3400	T3401	nsubj	they,are
R2613	T3619	T3620	nummod	27,]
R2614	T3620	T3609	attr	],are
R2615	T3621	T3609	punct	",",are
R2616	T3401	T3395	conj	are,clustered
R2617	T3622	T3609	advcl	suggesting,are
R2618	T3623	T3625	mark	that,is
R2619	T3624	T3625	csubj	silencing,is
R2620	T3625	T3622	ccomp	is,suggesting
R2621	T3626	T3627	advmod	primarily,gene
R2622	T3627	T3625	attr	gene,is
R2623	T3402	T3403	advmod	highly,homologous
R2624	T3628	T3627	amod	autonomous,gene
R2625	T3629	T3609	punct	.,are
R2626	T3630	T3654	csubj	Using,identified
R2627	T3403	T3401	acomp	homologous,are
R2628	T3631	T3632	compound	promoter,deletion
R2629	T3632	T3633	compound	deletion,analyses
R2630	T3633	T3630	dobj	analyses,Using
R2631	T3404	T3403	prep	to,homologous
R2632	T3634	T3633	prep	in,analyses
R2633	T3635	T3637	amod	transgenic,models
R2634	T3405	T3407	poss	their,counterparts
R2635	T3636	T3637	compound	mouse,models
R2636	T3637	T3634	pobj	models,in
R2637	T3638	T3637	cc	and,models
R2638	T3406	T3407	amod	human,counterparts
R2639	T3639	T3640	compound	cell,transfection
R2640	T3640	T3641	compound	transfection,assays
R2641	T3641	T3637	conj	assays,models
R2642	T3407	T3404	pobj	counterparts,to
R2643	T3642	T3641	punct	",",assays
R2644	T3643	T3645	amod	multiple,elements
R2645	T3408	T3407	prep	in,counterparts
R2646	T3644	T3645	compound	DNA,elements
R2647	T3645	T3641	conj	elements,assays
R2648	T3646	T3645	amod	important,elements
R2649	T3409	T3410	amod	organizational,structure
R2650	T3647	T3646	prep	to,important
R2651	T3648	T3650	det	the,process
R2652	T3649	T3650	amod	silencing,process
R2653	T3410	T3408	pobj	structure,in
R2654	T3650	T3647	pobj	process,to
R2655	T3651	T3654	aux	have,identified
R2656	T3652	T3654	auxpass	been,identified
R2657	T3702	T3688	punct	),shown
R2658	T3653	T3654	advmod	previously,identified
R2659	T3654	T3654	ROOT	identified,identified
R2660	T3655	T3654	prep	in,identified
R2661	T3656	T3658	preconj	both,proximal
R2662	T3703	T3704	aux	to,regulate
R2663	T3657	T3658	det	the,proximal
R2664	T3658	T3655	pobj	proximal,in
R2665	T3659	T3658	cc	and,proximal
R2666	T3704	T3688	advcl	regulate,shown
R2667	T3660	T3664	det	the,promoter
R2668	T3661	T3664	amod	distal,promoter
R2669	T3662	T3664	compound	ɛ,promoter
R2670	T3705	T3704	dobj	ɛ,regulate
R2671	T3663	T3664	compound	gene,promoter
R2672	T3664	T3658	conj	promoter,proximal
R2673	T3665	T3667	nmod	[,]
R2674	T3706	T3705	acl	silencing,ɛ
R2675	T3666	T3667	nummod	27,]
R2676	T3667	T3664	appos	],promoter
R2677	T3707	T3709	nmod	[,]
R2678	T3668	T3654	punct	.,identified
R2679	T3669	T3672	poss	Their,factors
R2680	T3670	T3672	amod	corresponding,factors
R2681	T3708	T3709	nummod	27,]
R2682	T3671	T3672	compound	transcription,factors
R2683	T3709	T3706	dobj	],silencing
R2684	T3672	T3686	nsubjpass	factors,identified
R2685	T3673	T3672	punct	",",factors
R2686	T3674	T3675	amod	such,as
R2687	T3710	T3686	punct	.,identified
R2688	T3675	T3672	prep	as,factors
R2689	T3676	T3675	pobj	GATA-1,as
R2690	T3677	T3676	punct	",",GATA-1
R2691	T3711	T3714	advmod	Thus,appears
R2692	T3678	T3676	conj	YY-1,GATA-1
R2693	T3679	T3678	punct	",",YY-1
R2694	T3712	T3714	punct	",",appears
R2695	T3680	T3678	conj	COUP-TF,YY-1
R2696	T3681	T3680	punct	",",COUP-TF
R2697	T3682	T3680	cc	and,COUP-TF
R2698	T3713	T3714	nsubj	it,appears
R2699	T3683	T3680	conj	DRED,COUP-TF
R2700	T3684	T3686	aux	have,identified
R2701	T3685	T3686	auxpass	been,identified
R2702	T3714	T3714	ROOT	appears,appears
R2703	T3686	T3686	ROOT	identified,identified
R2704	T3687	T3686	cc	and,identified
R2705	T3688	T3686	conj	shown,identified
R2706	T3715	T3722	mark	that,involves
R2707	T3689	T3691	aux	to,bind
R2708	T3690	T3691	advmod	directly,bind
R2709	T3691	T3688	xcomp	bind,shown
R2710	T3716	T3717	det	the,silencing
R2711	T3692	T3691	prep	to,bind
R2712	T3693	T3695	det	these,elements
R2713	T3694	T3695	compound	DNA,elements
R2714	T3717	T3722	nsubj	silencing,involves
R2715	T3695	T3692	pobj	elements,to
R2716	T3696	T3695	punct	(,elements
R2717	T3697	T3688	prep	as,shown
R2718	T3698	T3697	pobj	part,as
R2719	T3699	T3698	prep	of,part
R2720	T3700	T3701	compound	protein,complexes
R2721	T3718	T3717	prep	of,silencing
R2722	T3701	T3699	pobj	complexes,of
R2723	T3719	T3721	det	the,gene
R2724	T3720	T3721	compound	ɛ,gene
R2725	T3721	T3718	pobj	gene,of
R2726	T3799	T3799	ROOT	describe,describe
R2727	T3722	T3714	ccomp	involves,appears
R2728	T3723	T3725	det	a,network
R2729	T3800	T3803	mark	that,exerts
R2730	T3801	T3803	nsubj	Sox6,exerts
R2731	T3724	T3725	amod	complicated,network
R2732	T3802	T3803	advmod	also,exerts
R2733	T3803	T3799	ccomp	exerts,describe
R2734	T3725	T3722	dobj	network,involves
R2735	T3804	T3805	amod	pleiotropic,effects
R2736	T3805	T3803	dobj	effects,exerts
R2737	T3726	T3725	prep	of,network
R2738	T3806	T3805	prep	on,effects
R2739	T3807	T3806	pobj	erythropoiesis,on
R2740	T3808	T3799	punct	.,describe
R2741	T3727	T3729	amod	multiple,elements
R2742	T3809	T3810	det	These,effects
R2743	T3810	T3811	nsubj	effects,include
R2744	T3728	T3729	compound	cis,elements
R2745	T3811	T3811	ROOT	include,include
R2746	T3812	T3813	amod	delayed,maturation
R2747	T3813	T3811	dobj	maturation,include
R2748	T3729	T3726	pobj	elements,of
R2749	T3814	T3813	prep	of,maturation
R2750	T3815	T3814	pobj	erythrocytes,of
R2751	T3816	T3819	punct	(,enucleate
R2752	T3730	T3729	cc	and,elements
R2753	T3817	T3819	nsubj	that,enucleate
R2754	T3818	T3819	advmod	normally,enucleate
R2755	T3731	T3732	amod	transacting,proteins
R2756	T3819	T3813	appos	enucleate,maturation
R2757	T3732	T3729	conj	proteins,elements
R2758	T3820	T3819	advmod	prior,enucleate
R2759	T3733	T3714	punct	.,appears
R2760	T3821	T3820	prep	to,prior
R2761	T3822	T3821	pcomp	entering,to
R2762	T3823	T3824	det	the,bloodstream
R2763	T3734	T3767	prep	In,shown
R2764	T3824	T3822	dobj	bloodstream,entering
R2765	T3825	T3827	nmod	[,]
R2766	T3826	T3827	nummod	27,]
R2767	T3735	T3734	pobj	addition,In
R2768	T3827	T3824	appos	],bloodstream
R2769	T3828	T3827	punct	),]
R2770	T3829	T3824	cc	and,bloodstream
R2771	T3830	T3831	amod	higher,expression
R2772	T3831	T3821	pobj	expression,to
R2773	T3832	T3831	prep	of,expression
R2774	T3736	T3735	prep	to,addition
R2775	T3833	T3835	amod	embryonic,genes
R2776	T3834	T3835	compound	globin,genes
R2777	T3835	T3832	pobj	genes,of
R2778	T3836	T3811	punct	.,include
R2779	T3737	T3736	pcomp	playing,to
R2780	T3837	T3840	det	The,effect
R2781	T3838	T3839	advmod	most,extreme
R2782	T3738	T3740	det	an,role
R2783	T3839	T3840	amod	extreme,effect
R2784	T3840	T3841	nsubj	effect,is
R2785	T3841	T3841	ROOT	is,is
R2786	T3739	T3740	amod	important,role
R2787	T3842	T3843	det	the,persistence
R2788	T3843	T3841	attr	persistence,is
R2789	T3844	T3843	prep	of,persistence
R2790	T3740	T3737	dobj	role,playing
R2791	T3845	T3846	amod	high,expression
R2792	T3846	T3844	pobj	expression,of
R2793	T3847	T3846	prep	of,expression
R2794	T3741	T3740	prep	in,role
R2795	T3848	T3852	det	the,gene
R2796	T3849	T3852	amod	embryonic,gene
R2797	T3742	T3743	det	the,development
R2798	T3850	T3852	compound	ɛy,gene
R2799	T3851	T3852	compound	globin,gene
R2800	T3852	T3847	pobj	gene,of
R2801	T3743	T3741	pobj	development,in
R2802	T3853	T3841	punct	.,is
R2803	T3854	T3856	advmod	Here,describe
R2804	T3855	T3856	nsubj	we,describe
R2805	T3744	T3743	prep	of,development
R2806	T3856	T3856	ROOT	describe,describe
R2807	T3857	T3856	cc	and,describe
R2808	T3745	T3748	det	the,system
R2809	T3858	T3856	conj	characterize,describe
R2810	T3859	T3860	det	the,effects
R2811	T3860	T3858	dobj	effects,characterize
R2812	T3746	T3748	amod	central,system
R2813	T3861	T3860	prep	of,effects
R2814	T3862	T3861	pobj	Sox6,of
R2815	T3863	T3860	prep	on,effects
R2816	T3747	T3748	amod	nervous,system
R2817	T3864	T3867	det	the,gene
R2818	T3865	T3867	amod	ɛy,gene
R2819	T3866	T3867	compound	globin,gene
R2820	T3867	T3863	pobj	gene,on
R2821	T3868	T3856	punct	.,describe
R2822	T3869	T3870	nsubj	We,show
R2823	T3748	T3744	pobj	system,of
R2824	T3870	T3870	ROOT	show,show
R2825	T3871	T3882	mark	that,represses
R2826	T3872	T3873	amod	Sox6,binds
R2827	T3749	T3767	advcl	[,shown
R2828	T3873	T3882	nsubj	binds,represses
R2829	T3874	T3873	prep	to,binds
R2830	T3875	T3877	det	the,promoter
R2831	T3750	T3749	nummod	8,[
R2832	T3876	T3877	amod	proximal,promoter
R2833	T3877	T3874	pobj	promoter,to
R2834	T3878	T3877	prep	of,promoter
R2835	T3751	T3752	nummod	11,]
R2836	T3879	T3880	amod	ɛy,globin
R2837	T3880	T3878	pobj	globin,of
R2838	T3881	T3877	cc	and,promoter
R2839	T3752	T3749	appos	],[
R2840	T3882	T3870	ccomp	represses,show
R2841	T3883	T3884	poss	its,transcription
R2842	T3884	T3882	dobj	transcription,represses
R2843	T3753	T3752	punct	",",]
R2844	T3885	T3870	punct	.,show
R2845	T3886	T3896	prep	In,expressed
R2846	T3754	T3757	compound	cartilage,]
R2847	T3887	T3891	nmod	wild-type,mice
R2848	T3888	T3889	punct	(,WT
R2849	T3889	T3887	appos	WT,wild-type
R2850	T3755	T3757	compound	[,]
R2851	T3890	T3889	punct	),WT
R2852	T3891	T3886	pobj	mice,In
R2853	T3892	T3896	punct	",",expressed
R2854	T3756	T3757	compound	"6,12,13",]
R2855	T3893	T3896	nsubjpass	Sox6,expressed
R2856	T3894	T3896	auxpass	is,expressed
R2857	T3895	T3896	neg	not,expressed
R2858	T3757	T3749	conj	],[
R2859	T3758	T3757	punct	",",]
R2860	T3896	T3896	ROOT	expressed,expressed
R2861	T3759	T3757	cc	and,]
R2862	T3897	T3896	prep	in,expressed
R2863	T3898	T3901	compound	yolk,islands
R2864	T3760	T3763	compound	muscle,]
R2865	T3761	T3763	compound	[,]
R2866	T3899	T3901	compound	sac,islands
R2867	T3900	T3901	compound	blood,islands
R2868	T3762	T3763	compound	"14,15",]
R2869	T3901	T3897	pobj	islands,in
R2870	T3902	T3896	punct	",",expressed
R2871	T3903	T3896	cc	but,expressed
R2872	T3904	T3905	auxpass	is,expressed
R2873	T3905	T3896	conj	expressed,expressed
R2874	T3906	T3905	prep	in,expressed
R2875	T3763	T3757	conj	],]
R2876	T3907	T3908	amod	fetal,liver
R2877	T3908	T3906	pobj	liver,in
R2878	T3764	T3767	punct	",",shown
R2879	T3909	T3905	punct	",",expressed
R2880	T3910	T3913	det	the,pattern
R2881	T3765	T3767	nsubjpass	it,shown
R2882	T3911	T3913	amod	opposite,pattern
R2883	T3912	T3913	compound	expression,pattern
R2884	T3913	T3905	conj	pattern,expressed
R2885	T3766	T3767	auxpass	was,shown
R2886	T3914	T3913	prep	of,pattern
R2887	T3915	T3916	amod	ɛy,globin
R2888	T3767	T3767	ROOT	shown,shown
R2889	T3916	T3914	pobj	globin,of
R2890	T3917	T3896	punct	.,expressed
R2891	T3918	T3928	prep	In,expressed
R2892	T3768	T3770	mark	that,is
R2893	T3919	T3920	det	the,absence
R2894	T3920	T3918	pobj	absence,In
R2895	T3921	T3920	prep	of,absence
R2896	T3769	T3770	nsubj	Sox6,is
R2897	T3922	T3921	pobj	Sox6,of
R2898	T3923	T3928	punct	",",expressed
R2899	T3924	T3925	amod	ɛy,globin
R2900	T3770	T3767	ccomp	is,shown
R2901	T3925	T3928	nsubjpass	globin,expressed
R2902	T3926	T3928	auxpass	is,expressed
R2903	T3771	T3770	acomp	upregulated,is
R2904	T3927	T3928	advmod	ectopically,expressed
R2905	T3928	T3928	ROOT	expressed,expressed
R2906	T3929	T3928	prep	in,expressed
R2907	T3772	T3771	prep	in,upregulated
R2908	T3930	T3932	det	the,liver
R2909	T3931	T3932	amod	fetal,liver
R2910	T3932	T3929	pobj	liver,in
R2911	T3773	T3776	amod	long-term,cells
R2912	T3933	T3928	punct	",",expressed
R2913	T3934	T3928	advcl	demonstrating,expressed
R2914	T3935	T3934	dobj	that,demonstrating
R2915	T3774	T3776	compound	hematopoiesis,cells
R2916	T3936	T3937	amod	Sox6,functions
R2917	T3937	T3935	nsubj	functions,that
R2918	T3775	T3776	compound	stem,cells
R2919	T3938	T3937	prep	in,functions
R2920	T3939	T3940	amod	definitive,erythropoiesis
R2921	T3940	T3938	pobj	erythropoiesis,in
R2922	T3941	T3928	punct	.,expressed
R2923	T3776	T3772	pobj	cells,in
R2924	T3777	T3778	punct	(,LT-HSC
R2925	T3778	T3771	appos	LT-HSC,upregulated
R2926	T3779	T3771	punct	),upregulated
R2927	T3780	T3771	prep	compared,upregulated
R2928	T3781	T3780	prep	with,compared
R2929	T3782	T3783	amod	multipotent,progenitors
R2933	T3783	T3781	pobj	progenitors,with
R2934	T3784	T3783	prep	of,progenitors
R2938	T3785	T3788	compound	adult,marrow
R2939	T3786	T3788	compound	mouse,marrow
R2940	T3787	T3788	compound	bone,marrow
R2941	T3788	T3789	compound	marrow,lineage
R2943	T3789	T3784	pobj	lineage,of
R2944	T3790	T3792	nmod	[,]
R2945	T3791	T3792	nummod	28,]
R2946	T3792	T3783	appos	],progenitors
R2948	T3793	T3767	punct	.,shown
R2952	T3794	T3799	prep	In,describe
R2953	T3795	T3796	det	this,study
R2954	T3796	T3794	pobj	study,In
R2956	T3797	T3799	punct	",",describe
R2957	T3798	T3799	nsubj	we,describe

bionlp-st-ge-2016-test-tees

Id	Subject	Object	Predicate	Lexical cue
T1587	5477-5484	Negative_regulation	denotes	absence
T1586	5568-5572	Protein	denotes	Sox6
T1585	5494-5503	Protein	denotes	ɛy globin
T1584	5488-5492	Protein	denotes	Sox6
T1583	5437-5447	Gene_expression	denotes	expression
T1582	5398-5407	Gene_expression	denotes	expressed
T1581	5398-5407	Gene_expression	denotes	expressed
T1580	5354-5363	Gene_expression	denotes	expressed
T1579	5459-5468	Protein	denotes	ɛy globin
T1578	5342-5346	Protein	denotes	Sox6
T1577	5289-5298	Negative_regulation	denotes	represses
T1576	5241-5246	Binding	denotes	binds
T1575	5241-5246	Binding	denotes	binds
T1574	5303-5316	Transcription	denotes	transcription
T1573	5263-5271	Entity	denotes	promoter
T1572	5275-5284	Protein	denotes	ɛy globin
T1571	5236-5240	Protein	denotes	Sox6
T1570	5184-5191	Regulation	denotes	effects
T1569	5207-5221	Protein	denotes	ɛy globin gene
T1568	5195-5199	Protein	denotes	Sox6
T1567	5102-5112	Gene_expression	denotes	expression
T1566	5133-5144	Protein	denotes	globin gene
T1565	5013-5023	Gene_expression	denotes	expression
T1564	5037-5049	Protein	denotes	globin genes
T1563	4824-4828	Protein	denotes	Sox6
T1562	4654-4665	Positive_regulation	denotes	upregulated
T1561	4646-4650	Protein	denotes	Sox6
T1560	4269-4273	Binding	denotes	bind
T1559	4208-4215	Protein	denotes	COUP-TF
T1558	4202-4206	Protein	denotes	YY-1
T1557	4194-4200	Protein	denotes	GATA-1
T1556	3769-3778	Negative_regulation	denotes	silencing
T1555	3783-3796	Protein	denotes	ɛ globin gene
T1554	3680-3690	Regulation	denotes	controlled
T1553	3680-3690	Regulation	denotes	controlled
T1552	3670-3676	Entity	denotes	switch
T1551	3655-3669	Protein	denotes	adult β-globin
T1550	3643-3651	Protein	denotes	γ-globin
T1549	3395-3404	Negative_regulation	denotes	silencing
T1548	3431-3439	Protein	denotes	ɛ globin
T1547	3273-3280	Gene_expression	denotes	express
T1546	3281-3296	Protein	denotes	adult β globins
T1545	3085-3103	Protein	denotes	embryonic yolk sac
T1544	2986-2995	Gene_expression	denotes	expressed
T1543	2967-2981	Protein	denotes	β-globin genes
T1542	2567-2581	Protein	denotes	mouse β-globin
T1541	2530-2538	Regulation	denotes	modulate
T1540	2539-2547	Protein	denotes	β-globin
T1539	2498-2510	Protein	denotes	HMG proteins
T1538	2320-2332	Protein	denotes	HMG proteins
T1537	2234-2243	Gene_expression	denotes	expressed
T1536	2234-2243	Gene_expression	denotes	expressed
T1535	2140-2144	Binding	denotes	bind
T1534	2253-2266	Protein	denotes	HMG2 proteins
T1533	2244-2248	Protein	denotes	HMG1
T1532	2092-2123	Protein	denotes	Sox transcription factor family
T1531	2052-2055	Protein	denotes	Sry
T1530	2014-2030	Protein	denotes	HMG box proteins
T1529	1939-1964	Protein	denotes	Sox6 transcription factor
T1528	1889-1895	Protein	denotes	p gene
T1527	1751-1759	Positive_regulation	denotes	disrupts
T1526	1784-1793	Protein	denotes	Sox6 gene
T1525	1682-1687	Protein	denotes	p100H
T1524	1560-1565	Protein	denotes	p100H
T1523	1454-1458	Protein	denotes	Sox6
T1522	1295-1299	Protein	denotes	Sox6
T1521	1209-1213	Protein	denotes	Sox6
T1520	1045-1055	Gene_expression	denotes	expression
T1519	1045-1055	Gene_expression	denotes	expression
T1518	1045-1055	Gene_expression	denotes	expression
T1517	1045-1055	Gene_expression	denotes	expression
T1516	960-969	Localization	denotes	Depletion
T1515	1099-1102	Protein	denotes	Sry
T1514	1090-1094	Protein	denotes	Sox9
T1513	1084-1088	Protein	denotes	Sox6
T1512	1063-1073	Protein	denotes	HMG domain
T1511	973-977	Protein	denotes	Sox6
T1510	855-859	Protein	denotes	Sox6
T1509	693-697	Protein	denotes	Sox6
T1508	457-469	Protein	denotes	Sox proteins
T1507	253-257	Binding	denotes	bind
T1506	227-230	Protein	denotes	Sox
T1505	42-48	Binding	denotes	member
T1504	42-48	Binding	denotes	member
T1503	42-48	Binding	denotes	member
T1502	56-87	Protein	denotes	Sox transcription factor family
T1501	31-35	Protein	denotes	Sox6
T1500	13-29	Protein	denotes	Sry type HMG box
R753	T1500	T1504	themeOf	Sry type HMG box,member
R754	T1501	T1503	themeOf	Sox6,member
R755	T1501	T1505	themeOf	Sox6,member
R756	T1502	T1504	themeOf	Sox transcription factor family,member
R757	T1502	T1505	themeOf	Sox transcription factor family,member
R758	T1506	T1507	themeOf	Sox,bind
R759	T1511	T1516	themeOf	Sox6,Depletion
R760	T1512	T1517	themeOf	HMG domain,expression
R761	T1513	T1518	themeOf	Sox6,expression
R762	T1514	T1519	themeOf	Sox9,expression
R763	T1515	T1520	themeOf	Sry,expression
R764	T1526	T1527	themeOf	Sox6 gene,disrupts
R765	T1531	T1535	themeOf	Sry,bind
R766	T1533	T1536	themeOf	HMG1,expressed
R767	T1534	T1537	themeOf	HMG2 proteins,expressed
R768	T1539	T1541	causeOf	HMG proteins,modulate
R769	T1540	T1541	themeOf	β-globin,modulate
R770	T1543	T1544	themeOf	β-globin genes,expressed
R771	T1546	T1547	themeOf	adult β globins,express
R772	T1548	T1549	themeOf	ɛ globin,silencing
R773	T1550	T1553	themeOf	γ-globin,controlled
R774	T1550	T1552	partOf	γ-globin,switch
R775	T1551	T1554	themeOf	adult β-globin,controlled
R776	T1551	T1552	partOf	adult β-globin,switch
R777	T1552	T1553	Site	switch,controlled
R778	T1552	T1554	Site	switch,controlled
R779	T1555	T1556	themeOf	ɛ globin gene,silencing
R780	T1558	T1560	themeOf	YY-1,bind
R781	T1561	T1562	themeOf	Sox6,upregulated
R782	T1564	T1565	themeOf	globin genes,expression
R783	T1566	T1567	themeOf	globin gene,expression
R784	T1568	T1570	causeOf	Sox6,effects
R785	T1569	T1570	themeOf	ɛy globin gene,effects
R786	T1571	T1575	themeOf	Sox6,binds
R787	T1571	T1576	themeOf	Sox6,binds
R788	T1571	T1577	causeOf	Sox6,represses
R789	T1572	T1574	themeOf	ɛy globin,transcription
R790	T1572	T1576	themeOf	ɛy globin,binds
R791	T1572	T1573	partOf	ɛy globin,promoter
R792	T1573	T1575	Site	promoter,binds
R793	T1573	T1576	Site	promoter,binds
R794	T1574	T1577	themeOf	transcription,represses
R795	T1578	T1580	themeOf	Sox6,expressed
R796	T1578	T1581	themeOf	Sox6,expressed
R797	T1579	T1582	themeOf	ɛy globin,expressed
R798	T1579	T1583	themeOf	ɛy globin,expression
R799	T1585	T1587	themeOf	ɛy globin,absence

testone

Id	Subject	Object	Predicate	Lexical cue
T1065	5519-5528	Gene_expression	denotes	expressed
T1064	5477-5484	Negative_regulation	denotes	absence
T1063	5437-5447	Gene_expression	denotes	expression
T1062	5398-5407	Gene_expression	denotes	expressed
T1061	5354-5363	Gene_expression	denotes	expressed
T1060	5289-5298	Negative_regulation	denotes	represses
T1059	5263-5271	Entity	denotes	promoter
T1058	5254-5262	Entity	denotes	proximal
T1057	5241-5246	Binding	denotes	binds
T1056	5184-5191	Regulation	denotes	effects
T1055	5102-5112	Gene_expression	denotes	expression
T1054	4654-4665	Positive_regulation	denotes	upregulated
T1053	4383-4392	Negative_regulation	denotes	silencing
T1052	4341-4350	Negative_regulation	denotes	silencing
T1051	4330-4338	Regulation	denotes	regulate
T1050	4269-4273	Binding	denotes	bind
T1049	3866-3875	Negative_regulation	denotes	silencing
T1048	3769-3778	Negative_regulation	denotes	silencing
T1047	3703-3714	Negative_regulation	denotes	competition
T1046	3694-3702	Entity	denotes	promoter
T1045	3680-3690	Regulation	denotes	controlled
T1044	3609-3618	Regulation	denotes	regulated
T1043	3506-3515	Positive_regulation	denotes	activated
T1042	3395-3404	Negative_regulation	denotes	silencing
T1041	3273-3280	Gene_expression	denotes	express
T1040	3136-3143	Gene_expression	denotes	express
T1039	2986-2995	Gene_expression	denotes	expressed
T1038	2530-2538	Regulation	denotes	modulate
T1037	2234-2243	Gene_expression	denotes	expressed
T1036	2140-2144	Binding	denotes	bind
T1035	1751-1759	Negative_regulation	denotes	disrupts
T1034	1045-1055	Gene_expression	denotes	expression
T1033	253-257	Binding	denotes	bind
T1032	214-221	Binding	denotes	binding
T1031	5568-5572	Protein	denotes	Sox6
T1030	5494-5503	Protein	denotes	ɛy globin
T1029	5488-5492	Protein	denotes	Sox6
T1028	5459-5468	Protein	denotes	ɛy globin
T1027	5342-5346	Protein	denotes	Sox6
T1026	5275-5284	Protein	denotes	ɛy globin
T1025	5236-5240	Protein	denotes	Sox6
T1024	5207-5216	Protein	denotes	ɛy globin
T1023	5195-5199	Protein	denotes	Sox6
T1022	5130-5139	Protein	denotes	ɛy globin
T1021	4824-4828	Protein	denotes	Sox6
T1020	4646-4650	Protein	denotes	Sox6
T1019	4400-4401	Protein	denotes	ɛ
T1018	4339-4340	Protein	denotes	ɛ
T1017	4221-4225	Protein	denotes	DRED
T1016	4208-4215	Protein	denotes	COUP-TF
T1015	4202-4206	Protein	denotes	YY-1
T1014	4194-4200	Protein	denotes	GATA-1
T1013	4121-4122	Protein	denotes	ɛ
T1012	3812-3813	Protein	denotes	ɛ
T1011	3783-3791	Protein	denotes	ɛ globin
T1010	3661-3669	Protein	denotes	β-globin
T1009	3643-3651	Protein	denotes	γ-globin
T1008	3588-3589	Protein	denotes	ɛ
T1007	3501-3502	Protein	denotes	ɛ
T1006	3431-3439	Protein	denotes	ɛ globin
T1005	3327-3329	Protein	denotes	ɛy
T1004	3310-3315	Protein	denotes	minor
T1003	3298-3305	Protein	denotes	β major
T1002	3151-3163	Protein	denotes	βh-1 globins
T1001	3144-3146	Protein	denotes	ɛy
T1000	2949-2951	Protein	denotes	ɛy
T999	2611-2618	Protein	denotes	β-minor
T998	2598-2605	Protein	denotes	β-major
T997	2593-2596	Protein	denotes	βh1
T996	2589-2591	Protein	denotes	ɛy
T995	2253-2257	Protein	denotes	HMG2
T994	2244-2248	Protein	denotes	HMG1
T993	2052-2055	Protein	denotes	Sry
T992	1939-1943	Protein	denotes	Sox6
T991	1889-1890	Protein	denotes	p
T990	1784-1788	Protein	denotes	Sox6
T989	1769-1770	Protein	denotes	p
T988	1454-1458	Protein	denotes	Sox6
T987	1295-1299	Protein	denotes	Sox6
T986	1209-1213	Protein	denotes	Sox6
T985	1099-1102	Protein	denotes	Sry
T984	1090-1094	Protein	denotes	Sox9
T983	1084-1088	Protein	denotes	Sox6
T982	973-977	Protein	denotes	Sox6
T981	855-859	Protein	denotes	Sox6
T980	693-697	Protein	denotes	Sox6
T979	31-35	Protein	denotes	Sox6
T978	13-16	Protein	denotes	Sry
R597	T978	T1032	themeOf	Sry,binding
R598	T979	T978	equivalentTo	Sox6,Sry
R599	T983	T1034	themeOf	Sox6,expression
R600	T984	T1034	themeOf	Sox9,expression
R601	T985	T1034	themeOf	Sry,expression
R602	T989	T1035	themeOf	p,disrupts
R603	T990	T1035	themeOf	Sox6,disrupts
R604	T993	T1036	themeOf	Sry,bind
R605	T994	T1037	themeOf	HMG1,expressed
R606	T995	T1037	themeOf	HMG2,expressed
R607	T1001	T1040	themeOf	ɛy,express
R608	T1002	T1040	themeOf	βh-1 globins,express
R609	T1003	T1041	themeOf	β major,express
R610	T1006	T1042	themeOf	ɛ globin,silencing
R611	T1007	T1044	themeOf	ɛ,regulated
R612	T1007	T1043	themeOf	ɛ,activated
R613	T1008	T1044	themeOf	ɛ,regulated
R614	T1011	T1048	themeOf	ɛ globin,silencing
R615	T1014	T1050	themeOf	GATA-1,bind
R616	T1015	T1050	themeOf	YY-1,bind
R617	T1016	T1050	themeOf	COUP-TF,bind
R618	T1017	T1050	themeOf	DRED,bind
R619	T1018	T1052	themeOf	ɛ,silencing
R620	T1019	T1053	themeOf	ɛ,silencing
R621	T1020	T1054	themeOf	Sox6,upregulated
R622	T1022	T1055	themeOf	ɛy globin,expression
R623	T1024	T1056	themeOf	ɛy globin,effects
R624	T1025	T1057	themeOf	Sox6,binds
R625	T1026	T1057	themeOf	ɛy globin,binds
R626	T1027	T1062	themeOf	Sox6,expressed
R627	T1027	T1063	themeOf	Sox6,expression
R628	T1027	T1061	themeOf	Sox6,expressed
R629	T1028	T1063	themeOf	ɛy globin,expression
R630	T1029	T1064	themeOf	Sox6,absence
R631	T1029	T1065	themeOf	Sox6,expressed
R632	T1030	T1065	themeOf	ɛy globin,expressed
R633	T1030	T1064	themeOf	ɛy globin,absence
R634	T1046	T1045	causeOf	promoter,controlled
R635	T1050	T1051	causeOf	bind,regulate
R636	T1052	T1051	themeOf	silencing,regulate
R637	T1057	T1060	causeOf	binds,represses
R638	T1059	T1057	themeOf	promoter,binds

test3

Id	Subject	Object	Predicate	Lexical cue
T1195	5568-5572	Protein	denotes	Sox6
T1168	3812-3813	Protein	denotes	ɛ
T1167	3783-3791	Protein	denotes	ɛ globin
T1166	3769-3778	Negative_regulation	denotes	silencing
T1165	3680-3690	Regulation	denotes	controlled
T1164	3661-3669	Protein	denotes	β-globin
T1163	3643-3651	Protein	denotes	γ-globin
T1162	3609-3618	Regulation	denotes	regulated
T1161	3588-3589	Protein	denotes	ɛ
T1160	3506-3515	Positive_regulation	denotes	activated
T1159	3501-3502	Protein	denotes	ɛ
T1158	3431-3439	Protein	denotes	ɛ globin
T1157	3395-3404	Negative_regulation	denotes	silencing
T1156	3327-3329	Protein	denotes	ɛy
T1155	3310-3315	Protein	denotes	minor
T1154	3298-3305	Protein	denotes	β major
T1153	3273-3280	Gene_expression	denotes	express
T1152	3151-3163	Protein	denotes	βh-1 globins
T1151	3144-3146	Protein	denotes	ɛy
T1150	3136-3143	Gene_expression	denotes	express
T1149	2986-2995	Gene_expression	denotes	expressed
T1148	2949-2951	Protein	denotes	ɛy
T1147	2611-2618	Protein	denotes	β-minor
T1146	2598-2605	Protein	denotes	β-major
T1145	2593-2596	Protein	denotes	βh1
T1144	2589-2591	Protein	denotes	ɛy
T1143	2530-2538	Regulation	denotes	modulate
T1142	2253-2257	Protein	denotes	HMG2
T1141	2244-2248	Protein	denotes	HMG1
T1140	2234-2243	Gene_expression	denotes	expressed
T1139	2140-2144	Binding	denotes	bind
T1138	2052-2055	Protein	denotes	Sry
T1137	1939-1943	Protein	denotes	Sox6
T1136	1889-1890	Protein	denotes	p
T1135	1784-1788	Protein	denotes	Sox6
T1134	1769-1770	Protein	denotes	p
T1133	1454-1458	Protein	denotes	Sox6
T1132	1295-1299	Protein	denotes	Sox6
T1131	1209-1213	Protein	denotes	Sox6
T1130	1099-1102	Protein	denotes	Sry
T1129	1090-1094	Protein	denotes	Sox9
T1128	1084-1088	Protein	denotes	Sox6
T1127	1067-1073	Entity	denotes	domain
T1126	1045-1055	Gene_expression	denotes	expression
T1125	973-977	Protein	denotes	Sox6
T1124	855-859	Protein	denotes	Sox6
T1123	693-697	Protein	denotes	Sox6
T1122	253-257	Binding	denotes	bind
T1121	31-35	Protein	denotes	Sox6
T1120	13-16	Protein	denotes	Sry
T1119	5568-5572	Protein	denotes	Sox6
T1118	5494-5503	Protein	denotes	ɛy globin
T1117	5488-5492	Protein	denotes	Sox6
T1116	5459-5468	Protein	denotes	ɛy globin
T1115	5342-5346	Protein	denotes	Sox6
T1114	5275-5284	Protein	denotes	ɛy globin
T1113	5236-5240	Protein	denotes	Sox6
T1112	5207-5216	Protein	denotes	ɛy globin
T1111	5195-5199	Protein	denotes	Sox6
T1110	5130-5139	Protein	denotes	ɛy globin
T1109	4824-4828	Protein	denotes	Sox6
T1108	4646-4650	Protein	denotes	Sox6
T1107	4400-4401	Protein	denotes	ɛ
T1106	4339-4340	Protein	denotes	ɛ
T1105	4221-4225	Protein	denotes	DRED
T1104	4208-4215	Protein	denotes	COUP-TF
T1103	4202-4206	Protein	denotes	YY-1
T1102	4194-4200	Protein	denotes	GATA-1
T1101	4121-4122	Protein	denotes	ɛ
T1100	3812-3813	Protein	denotes	ɛ
T1099	3783-3791	Protein	denotes	ɛ globin
T1098	3661-3669	Protein	denotes	β-globin
T1097	3643-3651	Protein	denotes	γ-globin
T1096	3588-3589	Protein	denotes	ɛ
T1095	3501-3502	Protein	denotes	ɛ
T1094	3431-3439	Protein	denotes	ɛ globin
T1093	3327-3329	Protein	denotes	ɛy
T1092	3310-3315	Protein	denotes	minor
T1091	3298-3305	Protein	denotes	β major
T1090	3151-3163	Protein	denotes	βh-1 globins
T1089	3144-3146	Protein	denotes	ɛy
T1088	2949-2951	Protein	denotes	ɛy
T1087	2611-2618	Protein	denotes	β-minor
T1086	2598-2605	Protein	denotes	β-major
T1085	2593-2596	Protein	denotes	βh1
T1084	2589-2591	Protein	denotes	ɛy
T1083	2253-2257	Protein	denotes	HMG2
T1082	2244-2248	Protein	denotes	HMG1
T1081	2052-2055	Protein	denotes	Sry
T1080	1939-1943	Protein	denotes	Sox6
T1079	1889-1890	Protein	denotes	p
T1078	1784-1788	Protein	denotes	Sox6
T1077	1769-1770	Protein	denotes	p
T1076	1454-1458	Protein	denotes	Sox6
T1075	1295-1299	Protein	denotes	Sox6
T1074	1209-1213	Protein	denotes	Sox6
T1073	1099-1102	Protein	denotes	Sry
T1072	1090-1094	Protein	denotes	Sox9
T1071	1084-1088	Protein	denotes	Sox6
T1070	973-977	Protein	denotes	Sox6
T1069	855-859	Protein	denotes	Sox6
T1068	693-697	Protein	denotes	Sox6
T1067	31-35	Protein	denotes	Sox6
T1066	13-16	Protein	denotes	Sry
T1194	5519-5528	Gene_expression	denotes	expressed
T1193	5494-5503	Protein	denotes	ɛy globin
T1192	5488-5492	Protein	denotes	Sox6
T1191	5459-5468	Protein	denotes	ɛy globin
T1190	5342-5346	Protein	denotes	Sox6
T1189	5275-5284	Protein	denotes	ɛy globin
T1188	5263-5271	Entity	denotes	promoter
T1187	5254-5262	Entity	denotes	proximal
T1186	5241-5246	Binding	denotes	binds
T1185	5236-5240	Protein	denotes	Sox6
T1184	5207-5216	Protein	denotes	ɛy globin
T1183	5195-5199	Protein	denotes	Sox6
T1182	5130-5139	Protein	denotes	ɛy globin
T1181	4824-4828	Protein	denotes	Sox6
T1180	4646-4650	Protein	denotes	Sox6
T1179	4400-4401	Protein	denotes	ɛ
T1178	4383-4392	Negative_regulation	denotes	silencing
T1177	4341-4350	Negative_regulation	denotes	silencing
T1176	4339-4340	Protein	denotes	ɛ
T1175	4330-4338	Regulation	denotes	regulate
T1174	4269-4273	Binding	denotes	bind
T1173	4221-4225	Protein	denotes	DRED
T1172	4208-4215	Protein	denotes	COUP-TF
T1171	4202-4206	Protein	denotes	YY-1
T1170	4194-4200	Protein	denotes	GATA-1
T1169	4121-4122	Protein	denotes	ɛ
R662	T1173	T1174	themeOf	DRED,bind
R663	T1173	T1175	causeOf	DRED,regulate
R664	T1174	T1175	causeOf	bind,regulate
R665	T1176	T1177	themeOf	ɛ,silencing
R666	T1177	T1175	themeOf	silencing,regulate
R667	T1179	T1178	themeOf	ɛ,silencing
R668	T1185	T1186	themeOf	Sox6,binds
R669	T1188	T1186	themeOf	promoter,binds
R670	T1192	T1194	themeOf	Sox6,expressed
R671	T1193	T1194	themeOf	ɛy globin,expressed
R672	T1193	T1195	themeOf	ɛy globin,Sox6
R639	T1128	T1126	themeOf	Sox6,expression
R640	T1129	T1126	themeOf	Sox9,expression
R641	T1130	T1126	themeOf	Sry,expression
R642	T1132	T1131	themeOf	Sox6,Sox6
R643	T1138	T1140	themeOf	Sry,expressed
R644	T1138	T1139	themeOf	Sry,bind
R645	T1141	T1139	themeOf	HMG1,bind
R646	T1141	T1140	themeOf	HMG1,expressed
R647	T1142	T1139	themeOf	HMG2,bind
R648	T1142	T1140	themeOf	HMG2,expressed
R649	T1151	T1150	themeOf	ɛy,express
R650	T1152	T1150	themeOf	βh-1 globins,express
R651	T1153	T1155	themeOf	express,minor
R652	T1154	T1155	themeOf	β major,minor
R653	T1158	T1157	themeOf	ɛ globin,silencing
R654	T1159	T1160	themeOf	ɛ,activated
R655	T1160	T1162	themeOf	activated,regulated
R656	T1167	T1166	themeOf	ɛ globin,silencing
R657	T1168	T1166	themeOf	ɛ,silencing
R658	T1170	T1174	themeOf	GATA-1,bind
R659	T1171	T1174	themeOf	YY-1,bind
R660	T1172	T1174	themeOf	COUP-TF,bind
R661	T1172	T1175	causeOf	COUP-TF,regulate

PMC:1359074 / 2842-8454 JSONTXT

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