PMC:1359074 / 12299-12795 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1359074","sourcedb":"PMC","sourceid":"1359074","source_url":"http://www.ncbi.nlm.nih.gov/pmc/1359074","text":"(B) Sox6 represses ɛy promoter activity in a dosage-dependent manner. In GM979 cells, the E-Luc ɛy promoter reporter construct was co-transfected (1) without overexpression of Sox6; (2–4) with increasing amounts of CMV-Sox6 overexpression vector; (5) with a truncated version of Sox6 that lacks its HMG domain; (6) with a mutant version of Sox6 (L386H) that has previously been shown to abolish interaction with CtBP2; or (7) with an empty reporter plasmid (without ɛy promoter and μLCR element).","tracks":[{"project":"sentences","denotations":[{"id":"T83","span":{"begin":0,"end":69},"obj":"Sentence"},{"id":"T84","span":{"begin":70,"end":496},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T83","pred":"source","obj":"sentences"},{"subj":"T84","pred":"source","obj":"sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"sentences","color":"#ec93b0","default":true}]}]}}