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2_test

Id Subject Object Predicate Lexical cue
16462943-1848707-85760991 492-494 1848707 denotes 30
16462943-2748594-85760992 599-601 2748594 denotes 31
16462943-12677004-85760993 968-970 12677004 denotes 32
16462943-11504872-85760994 2653-2654 11504872 denotes 5
16462943-11504872-85760995 2958-2959 11504872 denotes 5
16462943-11504872-85760996 3461-3462 11504872 denotes 5
T87948 492-494 1848707 denotes 30
T97917 599-601 2748594 denotes 31
T50696 968-970 12677004 denotes 32
T36890 2653-2654 11504872 denotes 5
T88558 2958-2959 11504872 denotes 5
T4443 3461-3462 11504872 denotes 5

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T6147 3184-3192 NN denotes promoter
T6146 3181-3183 JJ denotes ɛy
T6145 3177-3180 DT denotes the
T6144 3167-3176 VB denotes represses
T6143 3162-3166 NN denotes Sox6
T6142 3157-3161 IN denotes that
T6141 3146-3156 VB denotes indicating
T6140 3144-3145 -COMMA- denotes ,
T6139 3143-3144 -RRB- denotes )
T6138 3141-3143 NN denotes 2B
T6137 3134-3140 NN denotes Figure
T6136 3133-3134 -LRB- denotes (
T6135 3127-3132 NN denotes assay
T6134 3114-3126 NN denotes transfection
T6133 3110-3113 DT denotes the
T6132 3107-3109 IN denotes in
T6131 3098-3106 NN denotes promoter
T6130 3095-3097 JJ denotes ɛy
T6129 3091-3094 DT denotes the
T6128 3083-3090 VB denotes repress
T6127 3080-3082 TO denotes to
T6126 3072-3079 NN denotes ability
T6125 3068-3071 DT denotes the
T6124 3060-3067 VB denotes retains
T6123 3055-3059 NN denotes Sox6
T6122 3052-3054 IN denotes of
T6121 3044-3051 NN denotes version
T6120 3037-3043 JJ denotes mutant
T6119 3032-3036 DT denotes this
T6118 3030-3031 -COMMA- denotes ,
T6117 3023-3030 RB denotes However
T6116 3015-3021 NN denotes domain
T6115 3007-3014 NN denotes binding
T6114 3003-3006 NN denotes DNA
T6113 2999-3002 NN denotes HMG
T6112 2995-2998 DT denotes the
T6111 2992-2994 IN denotes in
T6110 2988-2991 RB denotes not
T6109 2985-2987 VB denotes is
T6108 2978-2984 NN denotes change
T6107 2973-2977 NN denotes acid
T6106 2967-2972 JJ denotes amino
T6105 2962-2966 DT denotes This
T6104 2959-2960 -RRB- denotes ]
T6103 2958-2959 CD denotes 5
T6102 2957-2958 -LRB- denotes [
T6101 2945-2956 NN denotes interaction
T6100 2934-2944 JJ denotes Sox6-CtBP2
T6099 2926-2933 VB denotes abolish
T6098 2923-2925 TO denotes to
T6097 2912-2922 JJ denotes sufficient
T6096 2909-2911 VB denotes be
T6095 2906-2908 TO denotes to
T6094 2897-2905 VB denotes reported
T6093 2886-2896 RB denotes previously
T6092 2881-2885 VB denotes been
T6091 2877-2880 VB denotes has
T6090 2872-2876 WDT denotes that
T6089 2864-2871 NN denotes protein
T6088 2859-2863 NN denotes Sox6
T6087 2855-2858 DT denotes the
T6086 2852-2854 IN denotes in
T6085 2850-2851 -RRB- denotes )
T6084 2845-2850 NN denotes L386H
T6083 2844-2845 -LRB- denotes (
T6082 2835-2843 NN denotes mutation
T6081 2829-2834 NN denotes point
T6080 2827-2828 DT denotes a
T6079 2816-2826 VB denotes introduced
T6078 2813-2815 PRP denotes we
T6077 2811-2812 -COMMA- denotes ,
T6076 2803-2811 NN denotes promoter
T6075 2800-2802 JJ denotes ɛy
T6074 2796-2799 DT denotes the
T6073 2793-2795 IN denotes of
T6072 2782-2792 NN denotes repression
T6071 2777-2781 NN denotes Sox6
T6070 2773-2776 IN denotes for
T6069 2764-2772 VB denotes required
T6068 2761-2763 VB denotes is
T6067 2755-2760 NN denotes CtBP2
T6066 2750-2754 IN denotes with
T6065 2738-2749 NN denotes interaction
T6064 2734-2737 DT denotes the
T6063 2726-2733 IN denotes whether
T6062 2714-2725 VB denotes investigate
T6061 2711-2713 TO denotes To
T6060 2708-2709 -RRB- denotes )
T6059 2704-2708 NN denotes data
T6058 2692-2703 JJ denotes unpublished
T6057 2691-2692 -LRB- denotes (
T6056 2685-2690 NN denotes cells
T6055 2679-2684 NN denotes GM979
T6054 2676-2678 IN denotes in
T6053 2666-2675 VB denotes expressed
T6052 2663-2665 VB denotes is
T6051 2657-2662 NN denotes CtBP2
T6050 2654-2655 -RRB- denotes ]
T6049 2653-2654 CD denotes 5
T6048 2652-2653 -LRB- denotes [
T6047 2643-2651 NN denotes promoter
T6046 2637-2642 NN denotes fgf-3
T6045 2633-2636 DT denotes the
T6044 2630-2632 IN denotes on
T6043 2628-2629 -COMMA- denotes ,
T6042 2623-2628 NN denotes CtBP2
T6041 2621-2622 -COMMA- denotes ,
T6040 2609-2621 NN denotes co-repressor
T6039 2599-2608 VB denotes expressed
T6038 2592-2598 RB denotes widely
T6037 2590-2591 DT denotes a
T6036 2585-2589 IN denotes with
T6035 2576-2584 VB denotes interact
T6034 2573-2575 TO denotes to
T6033 2569-2572 CC denotes and
T6032 2559-2568 NN denotes repressor
T6031 2557-2558 DT denotes a
T6030 2554-2556 IN denotes as
T6029 2550-2553 VB denotes act
T6028 2547-2549 TO denotes to
T6027 2541-2546 VB denotes shown
T6026 2536-2540 VB denotes been
T6025 2532-2535 VB denotes has
T6024 2527-2531 NN denotes Sox6
T6023 1139-1144 NN denotes level
T6022 1123-1138 JJ denotes transcriptional
T6021 1119-1122 DT denotes the
T6020 1116-1118 IN denotes at
T6019 1107-1115 NN denotes promoter
T6018 1104-1106 JJ denotes ɛy
T6017 1100-1103 DT denotes the
T6016 1092-1099 VB denotes repress
T6015 1089-1091 TO denotes to
T6014 1084-1088 VB denotes acts
T6013 1079-1083 NN denotes Sox6
T6012 1074-1078 IN denotes that
T6011 1065-1073 VB denotes indicate
T6010 1060-1064 NN denotes data
T6009 1054-1059 DT denotes These
T6008 1051-1052 -RRB- denotes )
T6007 1049-1051 NN denotes 2B
T6006 1042-1048 NN denotes Figure
T6005 1041-1042 -LRB- denotes (
T6004 1032-1040 NN denotes activity
T6003 1026-1031 NN denotes E-Luc
T6002 1018-1025 VB denotes repress
T6001 1015-1017 TO denotes to
T6000 1009-1014 VB denotes fails
T5999 1007-1008 -RRB- denotes )
T5998 1001-1007 NN denotes allele
T5997 995-1000 NN denotes mouse
T5996 988-994 NN denotes p 100H
T5995 984-987 DT denotes the
T5994 981-983 TO denotes to
T5993 973-980 JJ denotes similar
T5992 972-973 -LRB- denotes (
T5991 970-971 -RRB- denotes ]
T5990 968-970 CD denotes 32
T5989 967-968 -LRB- denotes [
T5988 960-966 NN denotes domain
T5987 956-959 NN denotes HMG
T5986 952-955 PRP-DOLLAR- denotes its
T5985 946-951 VB denotes lacks
T5984 941-945 WDT denotes that
T5983 933-940 NN denotes protein
T5982 928-932 NN denotes Sox6
T5981 918-927 VB denotes truncated
T5980 916-917 DT denotes a
T5979 913-915 IN denotes of
T5978 898-912 NN denotes overexpression
T5977 896-897 -COMMA- denotes ,
T5976 888-896 NN denotes contrast
T5975 885-887 IN denotes In
T5974 882-883 -RRB- denotes )
T5973 880-882 NN denotes 2B
T5972 873-879 NN denotes Figure
T5971 872-873 -LRB- denotes (
T5970 863-871 NN denotes activity
T5969 854-862 NN denotes reporter
T5968 848-853 NN denotes E-Luc
T5967 845-847 IN denotes of
T5966 834-844 NN denotes repression
T5965 817-833 JJ denotes dosage-dependent
T5964 815-816 DT denotes a
T5963 812-814 TO denotes to
T5962 806-811 VB denotes leads
T5961 793-805 NN denotes transfection
T5960 783-792 JJ denotes transient
T5959 780-782 IN denotes by
T5958 774-779 NN denotes cells
T5957 768-773 NN denotes GM979
T5956 765-767 IN denotes in
T5955 760-764 NN denotes Sox6
T5954 757-759 IN denotes of
T5953 742-756 NN denotes Overexpression
T5952 739-740 -RRB- denotes )
T5951 732-739 NNP denotes Methods
T5950 728-731 CC denotes and
T5949 718-727 NNP denotes Materials
T5948 715-717 IN denotes in
T5947 706-714 VB denotes detailed
T5946 705-706 -LRB- denotes (
T5945 702-704 NN denotes 2A
T5944 695-701 NN denotes Figure
T5943 692-694 IN denotes in
T5942 686-691 VB denotes shown
T5941 683-685 IN denotes as
T5940 681-682 -COMMA- denotes ,
T5939 677-681 NN denotes gene
T5938 668-676 NN denotes reporter
T5937 657-667 NN denotes luciferase
T5936 653-656 DT denotes the
T5935 650-652 IN denotes by
T5934 641-649 VB denotes followed
T5933 639-640 -COMMA- denotes ,
T5932 638-639 -RRB- denotes )
T6201 3474-3475 -RRB- denotes )
T6200 3472-3474 NN denotes 3A
T6199 3465-3471 NN denotes Figure
T6198 3464-3465 -LRB- denotes (
T6197 3462-3463 -RRB- denotes ]
T6196 3461-3462 CD denotes 5
T6195 3460-3461 -LRB- denotes [
T6194 3454-3459 NN denotes sites
T6193 3446-3453 NN denotes binding
T6192 3436-3445 NN denotes consensus
T6191 3427-3435 NN denotes Sox/Sox6
T6190 3423-3426 CD denotes two
T6189 3415-3422 VB denotes reveals
T6188 3408-3414 NN denotes region
T6187 3402-3407 JJ denotes short
T6186 3397-3401 DT denotes this
T6185 3394-3396 IN denotes of
T6184 3385-3393 NN denotes Analysis
T6183 3373-3383 NN denotes repression
T6182 3368-3372 NN denotes Sox6
T6181 3364-3367 IN denotes for
T6180 3355-3363 JJ denotes critical
T6179 3352-3354 VB denotes is
T6178 3347-3351 WDT denotes that
T6177 3338-3346 NN denotes promoter
T6176 3329-3337 JJ denotes proximal
T6175 3326-3328 JJ denotes ɛy
T6174 3322-3325 DT denotes the
T6173 3315-3321 IN denotes within
T6172 3313-3314 -RRB- denotes )
T6171 3310-3313 CD denotes −37
T6170 3307-3309 TO denotes to
T6169 3303-3306 CD denotes −63
T6168 3302-3303 -LRB- denotes (
T6167 3295-3301 NN denotes region
T6166 3293-3294 DT denotes a
T6165 3285-3292 VB denotes defined
T6164 3283-3284 -COMMA- denotes ,
T6163 3281-3283 NN denotes 2C
T6162 3274-3280 NN denotes Figure
T6161 3271-3273 IN denotes in
T6160 3265-3270 VB denotes shown
T6159 3262-3264 IN denotes as
T6158 3260-3261 -COMMA- denotes ,
T6157 3252-3260 NN denotes promoter
T6156 3249-3251 JJ denotes ɛy
T6155 3245-3248 DT denotes the
T6154 3242-3244 IN denotes of
T6153 3233-3241 NN denotes analysis
T6152 3224-3232 NN denotes Deletion
T6151 3216-3222 NN denotes manner
T6150 3198-3215 JJ denotes CtBP2-independent
T6149 3196-3197 DT denotes a
T6148 3193-3195 IN denotes in
T5931 636-638 NN denotes kb
T5930 632-635 CD denotes 2.2
T5929 631-632 -LRB- denotes (
T5928 622-630 NN denotes promoter
T5927 613-621 JJ denotes proximal
T5926 610-612 JJ denotes ɛy
T5925 606-609 DT denotes the
T5924 603-605 TO denotes to
T5923 601-602 -RRB- denotes ]
T5922 599-601 CD denotes 31
T5921 598-599 -LRB- denotes [
T5920 596-597 -RRB- denotes )
T5919 594-596 NN denotes kb
T5918 590-593 CD denotes 2.5
T5917 589-590 -LRB- denotes (
T5916 581-588 NN denotes element
T5915 579-580 -RRB- denotes )
T5914 575-579 NN denotes μLCR
T5913 574-575 -LRB- denotes (
T5912 564-573 NN denotes micro-LCR
T5911 562-563 DT denotes a
T5910 555-561 VB denotes fusing
T5909 552-554 IN denotes by
T5908 550-551 -RRB- denotes )
T5907 545-550 NN denotes E-Luc
T5906 544-545 -LRB- denotes (
T5905 534-543 NN denotes construct
T5904 525-533 NN denotes reporter
T5903 516-524 NN denotes promoter
T5902 513-515 JJ denotes ɛy
T5901 510-512 DT denotes an
T5900 500-509 VB denotes generated
T5899 497-499 PRP denotes We
T5898 494-495 -RRB- denotes ]
T5897 492-494 CD denotes 30
T5896 491-492 -LRB- denotes [
T5895 483-490 NN denotes globins
T5894 478-482 NN denotes beta
T5893 472-477 JJ denotes adult
T5892 468-471 CC denotes and
T5891 465-467 JJ denotes ɛy
T5890 460-464 CC denotes both
T5889 450-459 VB denotes expresses
T5888 445-449 WDT denotes that
T5887 440-444 NN denotes line
T5886 435-439 NN denotes cell
T5885 419-434 JJ denotes erythroleukemic
T5884 412-418 JJ denotes murine
T5883 410-411 DT denotes a
T5882 408-409 -COMMA- denotes ,
T5881 403-408 NN denotes cells
T5880 397-402 NN denotes GM979
T5879 393-396 CC denotes and
T5878 387-392 NN denotes assay
T5877 374-386 NN denotes transfection
T5876 364-373 JJ denotes transient
T5875 358-363 FW denotes vitro
T5874 355-357 FW denotes in
T5873 352-354 DT denotes an
T5872 347-351 VB denotes used
T5871 344-346 PRP denotes we
T5870 342-343 -COMMA- denotes ,
T5869 337-342 NN denotes level
T5868 321-336 JJ denotes transcriptional
T5867 317-320 DT denotes the
T5866 314-316 IN denotes at
T5865 305-313 NN denotes promoter
T5864 300-304 NN denotes gene
T5863 297-299 JJ denotes ɛy
T5862 293-296 DT denotes the
T5861 290-292 IN denotes on
T5860 285-289 VB denotes acts
T5859 276-284 RB denotes directly
T5858 271-275 NN denotes Sox6
T5857 263-270 IN denotes whether
T5856 251-262 VB denotes investigate
T5855 248-250 TO denotes To
T5854 238-246 NN denotes promoter
T5853 235-237 JJ denotes ɛy
T5852 231-234 DT denotes the
T5851 228-230 IN denotes of
T5850 219-227 NN denotes activity
T5849 203-218 JJ denotes transcriptional
T5848 199-202 RB denotes not
T5847 197-198 -COMMA- denotes ,
T5846 193-197 NN denotes mRNA
T5845 190-192 JJ denotes ɛy
T5844 187-189 IN denotes of
T5843 180-186 NN denotes levels
T5842 167-179 JJ denotes steady-state
T5841 159-166 NN denotes measure
T5840 157-158 -RRB- denotes )
T5839 156-157 CD denotes 1
T5838 149-155 NN denotes Figure
T5837 148-149 -LRB- denotes (
T5836 141-147 NN denotes assays
T5835 137-140 NN denotes PCR
T5834 127-136 JJ denotes Real-time
T5833 121-126 NNP denotes Level
T5832 105-120 NNP denotes Transcriptional
T5831 101-104 DT denotes the
T5830 98-100 IN denotes at
T5829 89-97 NN denotes Promoter
T5828 84-88 NN denotes Gene
T5827 81-83 JJ denotes ɛy
T5826 77-80 DT denotes the
T5825 67-76 VB denotes Represses
T5824 58-66 RB denotes Directly
T5823 53-57 NN denotes Sox6
T5822 48-52 DT denotes That
T5821 39-47 NNP denotes Indicate
T5820 33-38 NNP denotes Cells
T5819 27-32 NN denotes GM979
T5818 21-26 VB denotes Using
T5817 13-20 NN denotes Studies
T5816 0-12 NN denotes Transfection
R3966 T5817 T5816 arg1Of Studies,Transfection
R3967 T5817 T5818 arg1Of Studies,Using
R3968 T5817 T5825 arg1Of Studies,Represses
R3969 T5821 T5819 arg1Of Indicate,GM979
R3970 T5821 T5820 arg1Of Indicate,Cells
R3971 T5823 T5818 arg2Of Sox6,Using
R3972 T5823 T5821 arg1Of Sox6,Indicate
R3973 T5823 T5822 arg1Of Sox6,That
R3974 T5825 T5824 arg1Of Represses,Directly
R3975 T5829 T5825 arg2Of Promoter,Represses
R3976 T5829 T5826 arg1Of Promoter,the
R3977 T5829 T5827 arg1Of Promoter,ɛy
R3978 T5829 T5828 arg1Of Promoter,Gene
R3979 T5829 T5830 arg1Of Promoter,at
R3980 T5833 T5830 arg2Of Level,at
R3981 T5833 T5831 arg1Of Level,the
R3982 T5833 T5832 arg1Of Level,Transcriptional
R3983 T5838 T5837 arg2Of Figure,(
R3984 T5838 T5839 arg1Of Figure,1
R3985 T5840 T5837 arg3Of ),(
R3986 T5843 T5834 arg1Of levels,Real-time
R3987 T5843 T5835 arg1Of levels,PCR
R3988 T5843 T5836 arg1Of levels,assays
R3989 T5843 T5837 arg1Of levels,(
R3990 T5843 T5841 arg1Of levels,measure
R3991 T5843 T5842 arg1Of levels,steady-state
R3992 T5843 T5844 arg1Of levels,of
R3993 T5846 T5844 arg2Of mRNA,of
R3994 T5846 T5845 arg1Of mRNA,ɛy
R3995 T5846 T5847 arg1Of mRNA,","
R3996 T5850 T5847 arg2Of activity,","
R3997 T5850 T5848 arg1Of activity,not
R3998 T5850 T5849 arg1Of activity,transcriptional
R3999 T5850 T5851 arg1Of activity,of
R4000 T5854 T5851 arg2Of promoter,of
R4001 T5854 T5852 arg1Of promoter,the
R4002 T5854 T5853 arg1Of promoter,ɛy
R4003 T5856 T5855 arg1Of investigate,To
R4004 T5858 T5860 arg1Of Sox6,acts
R4005 T5860 T5856 arg2Of acts,investigate
R4006 T5860 T5857 arg1Of acts,whether
R4007 T5860 T5859 arg1Of acts,directly
R4008 T5860 T5861 arg1Of acts,on
R4009 T5860 T5866 arg1Of acts,at
R4010 T5865 T5861 arg2Of promoter,on
R4011 T5865 T5862 arg1Of promoter,the
R4012 T5865 T5863 arg1Of promoter,ɛy
R4013 T5865 T5864 arg1Of promoter,gene
R4014 T5869 T5866 arg2Of level,at
R4015 T5869 T5867 arg1Of level,the
R4016 T5869 T5868 arg1Of level,transcriptional
R4017 T5871 T5856 arg1Of we,investigate
R4018 T5871 T5872 arg1Of we,used
R4019 T5872 T5855 modOf used,To
R4020 T5872 T5870 arg1Of used,","
R4021 T5875 T5874 arg1Of vitro,in
R4022 T5876 T5875 arg1Of transient,vitro
R4023 T5878 T5873 arg1Of assay,an
R4024 T5878 T5876 arg1Of assay,transient
R4025 T5878 T5877 arg1Of assay,transfection
R4026 T5878 T5879 arg1Of assay,and
R4027 T5879 T5872 arg2Of and,used
R4028 T5881 T5879 arg2Of cells,and
R4029 T5881 T5880 arg1Of cells,GM979
R4030 T5881 T5882 arg1Of cells,","
R4031 T5887 T5882 arg2Of line,","
R4032 T5887 T5883 arg1Of line,a
R4033 T5887 T5884 arg1Of line,murine
R4034 T5887 T5885 arg1Of line,erythroleukemic
R4035 T5887 T5886 arg1Of line,cell
R4036 T5887 T5888 arg1Of line,that
R4037 T5887 T5889 arg1Of line,expresses
R4038 T5891 T5892 arg1Of ɛy,and
R4039 T5893 T5892 arg2Of adult,and
R4040 T5895 T5889 arg2Of globins,expresses
R4041 T5895 T5890 arg1Of globins,both
R4042 T5895 T5891 arg1Of globins,ɛy
R4043 T5895 T5893 arg1Of globins,adult
R4044 T5895 T5894 arg1Of globins,beta
R4045 T5895 T5896 arg1Of globins,[
R4046 T5897 T5896 arg2Of 30,[
R4047 T5898 T5896 arg3Of ],[
R4048 T5899 T5900 arg1Of We,generated
R4049 T5899 T5910 arg1Of We,fusing
R4050 T5900 T5909 arg1Of generated,by
R4051 T5900 T5940 arg1Of generated,","
R4052 T5900 T5941 arg1Of generated,as
R4053 T5905 T5900 arg2Of construct,generated
R4054 T5905 T5901 arg1Of construct,an
R4055 T5905 T5902 arg1Of construct,ɛy
R4056 T5905 T5903 arg1Of construct,promoter
R4057 T5905 T5904 arg1Of construct,reporter
R4058 T5905 T5906 arg1Of construct,(
R4059 T5907 T5906 arg2Of E-Luc,(
R4060 T5908 T5906 arg3Of ),(
R4061 T5910 T5909 arg2Of fusing,by
R4062 T5910 T5933 arg1Of fusing,","
R4063 T5910 T5934 modOf fusing,followed
R4064 T5914 T5913 arg2Of μLCR,(
R4065 T5915 T5913 arg3Of ),(
R4066 T5916 T5910 arg2Of element,fusing
R4067 T5916 T5911 arg1Of element,a
R4068 T5916 T5912 arg1Of element,micro-LCR
R4069 T5916 T5913 arg1Of element,(
R4070 T5916 T5917 arg1Of element,(
R4071 T5916 T5921 arg1Of element,[
R4072 T5916 T5924 arg1Of element,to
R4073 T5919 T5917 arg2Of kb,(
R4074 T5919 T5918 arg1Of kb,2.5
R4075 T5920 T5917 arg3Of ),(
R4076 T5922 T5921 arg2Of 31,[
R4077 T5923 T5921 arg3Of ],[
R4078 T5928 T5924 arg2Of promoter,to
R4079 T5928 T5925 arg1Of promoter,the
R4080 T5928 T5926 arg1Of promoter,ɛy
R4081 T5928 T5927 arg1Of promoter,proximal
R4082 T5928 T5929 arg1Of promoter,(
R4083 T5931 T5929 arg2Of kb,(
R4084 T5931 T5930 arg1Of kb,2.2
R4085 T5932 T5929 arg3Of ),(
R4086 T5939 T5934 arg1Of gene,followed
R4087 T5939 T5935 arg2Of gene,by
R4088 T5939 T5936 arg1Of gene,the
R4089 T5939 T5937 arg1Of gene,luciferase
R4090 T5939 T5938 arg1Of gene,reporter
R4091 T5942 T5941 arg2Of shown,as
R4092 T5942 T5943 arg1Of shown,in
R4093 T5945 T5943 arg2Of 2A,in
R4094 T5945 T5944 arg1Of 2A,Figure
R4095 T5945 T5946 arg1Of 2A,(
R4096 T5947 T5946 arg2Of detailed,(
R4097 T5947 T5948 arg1Of detailed,in
R4098 T5949 T5950 arg1Of Materials,and
R4099 T5950 T5948 arg2Of and,in
R4100 T5951 T5950 arg2Of Methods,and
R4101 T5952 T5946 arg3Of ),(
R4102 T5953 T5954 arg1Of Overexpression,of
R4103 T5953 T5956 arg1Of Overexpression,in
R4104 T5953 T5959 arg1Of Overexpression,by
R4105 T5953 T5962 arg1Of Overexpression,leads
R4106 T5955 T5954 arg2Of Sox6,of
R4107 T5958 T5956 arg2Of cells,in
R4108 T5958 T5957 arg1Of cells,GM979
R4109 T5961 T5959 arg2Of transfection,by
R4110 T5961 T5960 arg1Of transfection,transient
R4111 T5962 T5963 arg1Of leads,to
R4112 T5966 T5963 arg2Of repression,to
R4113 T5966 T5964 arg1Of repression,a
R4114 T5966 T5965 arg1Of repression,dosage-dependent
R4115 T5966 T5967 arg1Of repression,of
R4116 T5970 T5967 arg2Of activity,of
R4117 T5970 T5968 arg1Of activity,E-Luc
R4118 T5970 T5969 arg1Of activity,reporter
R4119 T5970 T5971 arg1Of activity,(
R4120 T5973 T5971 arg2Of 2B,(
R4121 T5973 T5972 arg1Of 2B,Figure
R4122 T5974 T5971 arg3Of ),(
R4123 T5976 T5975 arg2Of contrast,In
R4124 T5978 T5979 arg1Of overexpression,of
R4125 T5978 T6000 arg1Of overexpression,fails
R4126 T5978 T6002 arg1Of overexpression,repress
R4127 T5983 T5979 arg2Of protein,of
R4128 T5983 T5980 arg1Of protein,a
R4129 T5983 T5981 arg2Of protein,truncated
R4130 T5983 T5982 arg1Of protein,Sox6
R4131 T5983 T5984 arg1Of protein,that
R4132 T5983 T5985 arg1Of protein,lacks
R4133 T5983 T5992 arg1Of protein,(
R4134 T5985 T5989 arg1Of lacks,[
R4135 T5988 T5985 arg2Of domain,lacks
R4136 T5988 T5986 arg1Of domain,its
R4137 T5988 T5987 arg1Of domain,HMG
R4138 T5990 T5989 arg2Of 32,[
R4139 T5991 T5989 arg3Of ],[
R4140 T5993 T5992 arg2Of similar,(
R4141 T5993 T5994 arg1Of similar,to
R4142 T5998 T5994 arg2Of allele,to
R4143 T5998 T5995 arg1Of allele,the
R4144 T5998 T5996 arg1Of allele,p 100H
R4145 T5998 T5997 arg1Of allele,mouse
R4146 T5999 T5992 arg3Of ),(
R4147 T6000 T5975 arg1Of fails,In
R4148 T6000 T5977 arg1Of fails,","
R4149 T6002 T6000 arg2Of repress,fails
R4150 T6002 T6001 arg1Of repress,to
R4151 T6004 T6002 arg2Of activity,repress
R4152 T6004 T6003 arg1Of activity,E-Luc
R4153 T6004 T6005 arg1Of activity,(
R4154 T6007 T6005 arg2Of 2B,(
R4155 T6007 T6006 arg1Of 2B,Figure
R4156 T6008 T6005 arg3Of ),(
R4157 T6010 T6009 arg1Of data,These
R4158 T6010 T6011 arg1Of data,indicate
R4159 T6013 T6014 arg1Of Sox6,acts
R4160 T6013 T6016 arg1Of Sox6,repress
R4161 T6014 T6011 arg2Of acts,indicate
R4162 T6014 T6012 arg1Of acts,that
R4163 T6016 T6014 arg2Of repress,acts
R4164 T6016 T6015 arg1Of repress,to
R4165 T6016 T6020 arg1Of repress,at
R4166 T6019 T6016 arg2Of promoter,repress
R4167 T6019 T6017 arg1Of promoter,the
R4168 T6019 T6018 arg1Of promoter,ɛy
R4169 T6023 T6020 arg2Of level,at
R4170 T6023 T6021 arg1Of level,the
R4171 T6023 T6022 arg1Of level,transcriptional
R4172 T6024 T6025 arg1Of Sox6,has
R4173 T6024 T6026 arg1Of Sox6,been
R4174 T6024 T6027 arg2Of Sox6,shown
R4175 T6024 T6029 arg1Of Sox6,act
R4176 T6024 T6035 arg1Of Sox6,interact
R4177 T6027 T6025 arg2Of shown,has
R4178 T6027 T6026 arg2Of shown,been
R4179 T6027 T6048 arg1Of shown,[
R4180 T6029 T6028 arg1Of act,to
R4181 T6029 T6030 arg1Of act,as
R4182 T6029 T6033 arg1Of act,and
R4183 T6032 T6030 arg2Of repressor,as
R4184 T6032 T6031 arg1Of repressor,a
R4185 T6033 T6027 arg3Of and,shown
R4186 T6035 T6033 arg2Of interact,and
R4187 T6035 T6034 arg1Of interact,to
R4188 T6035 T6036 arg1Of interact,with
R4189 T6039 T6038 arg1Of expressed,widely
R4190 T6040 T6036 arg2Of co-repressor,with
R4191 T6040 T6037 arg1Of co-repressor,a
R4192 T6040 T6039 arg1Of co-repressor,expressed
R4193 T6040 T6041 arg1Of co-repressor,","
R4194 T6040 T6043 arg1Of co-repressor,","
R4195 T6040 T6044 arg1Of co-repressor,on
R4196 T6042 T6041 arg2Of CtBP2,","
R4197 T6047 T6044 arg2Of promoter,on
R4198 T6047 T6045 arg1Of promoter,the
R4199 T6047 T6046 arg1Of promoter,fgf-3
R4200 T6049 T6048 arg2Of 5,[
R4201 T6050 T6048 arg3Of ],[
R4202 T6051 T6052 arg1Of CtBP2,is
R4203 T6051 T6053 arg2Of CtBP2,expressed
R4204 T6053 T6052 arg2Of expressed,is
R4205 T6053 T6054 arg1Of expressed,in
R4206 T6056 T6054 arg2Of cells,in
R4207 T6056 T6055 arg1Of cells,GM979
R4208 T6056 T6057 arg1Of cells,(
R4209 T6059 T6057 arg2Of data,(
R4210 T6059 T6058 arg1Of data,unpublished
R4211 T6060 T6057 arg3Of ),(
R4212 T6062 T6061 arg1Of investigate,To
R4213 T6065 T6064 arg1Of interaction,the
R4214 T6065 T6066 arg1Of interaction,with
R4215 T6065 T6068 arg1Of interaction,is
R4216 T6065 T6069 arg2Of interaction,required
R4217 T6067 T6066 arg2Of CtBP2,with
R4218 T6069 T6062 arg2Of required,investigate
R4219 T6069 T6063 arg1Of required,whether
R4220 T6069 T6068 arg2Of required,is
R4221 T6069 T6070 arg1Of required,for
R4222 T6072 T6070 arg2Of repression,for
R4223 T6072 T6071 arg1Of repression,Sox6
R4224 T6072 T6073 arg1Of repression,of
R4225 T6076 T6073 arg2Of promoter,of
R4226 T6076 T6074 arg1Of promoter,the
R4227 T6076 T6075 arg1Of promoter,ɛy
R4228 T6078 T6062 arg1Of we,investigate
R4229 T6078 T6079 arg1Of we,introduced
R4230 T6079 T6061 modOf introduced,To
R4231 T6079 T6077 arg1Of introduced,","
R4232 T6082 T6079 arg2Of mutation,introduced
R4233 T6082 T6080 arg1Of mutation,a
R4234 T6082 T6081 arg1Of mutation,point
R4235 T6082 T6083 arg1Of mutation,(
R4236 T6082 T6086 arg1Of mutation,in
R4237 T6084 T6083 arg2Of L386H,(
R4238 T6085 T6083 arg3Of ),(
R4239 T6089 T6086 arg2Of protein,in
R4240 T6089 T6087 arg1Of protein,the
R4241 T6089 T6088 arg1Of protein,Sox6
R4242 T6089 T6090 arg1Of protein,that
R4243 T6089 T6091 arg1Of protein,has
R4244 T6089 T6092 arg1Of protein,been
R4245 T6089 T6094 arg2Of protein,reported
R4246 T6089 T6096 arg1Of protein,be
R4247 T6089 T6097 arg1Of protein,sufficient
R4248 T6094 T6091 arg2Of reported,has
R4249 T6094 T6092 arg2Of reported,been
R4250 T6094 T6093 arg1Of reported,previously
R4251 T6096 T6094 arg3Of be,reported
R4252 T6096 T6095 arg1Of be,to
R4253 T6097 T6096 arg2Of sufficient,be
R4254 T6099 T6097 arg2Of abolish,sufficient
R4255 T6099 T6098 arg1Of abolish,to
R4256 T6101 T6099 arg2Of interaction,abolish
R4257 T6101 T6100 arg1Of interaction,Sox6-CtBP2
R4258 T6101 T6102 arg1Of interaction,[
R4259 T6103 T6102 arg2Of 5,[
R4260 T6104 T6102 arg3Of ],[
R4261 T6108 T6105 arg1Of change,This
R4262 T6108 T6106 arg1Of change,amino
R4263 T6108 T6107 arg1Of change,acid
R4264 T6108 T6109 arg1Of change,is
R4265 T6108 T6111 arg1Of change,in
R4266 T6109 T6110 arg1Of is,not
R4267 T6111 T6109 arg2Of in,is
R4268 T6116 T6111 arg2Of domain,in
R4269 T6116 T6112 arg1Of domain,the
R4270 T6116 T6113 arg1Of domain,HMG
R4271 T6116 T6114 arg1Of domain,DNA
R4272 T6116 T6115 arg1Of domain,binding
R4273 T6121 T6119 arg1Of version,this
R4274 T6121 T6120 arg1Of version,mutant
R4275 T6121 T6122 arg1Of version,of
R4276 T6121 T6124 arg1Of version,retains
R4277 T6123 T6122 arg2Of Sox6,of
R4278 T6124 T6117 arg1Of retains,However
R4279 T6124 T6118 arg1Of retains,","
R4280 T6124 T6140 arg1Of retains,","
R4281 T6124 T6141 modOf retains,indicating
R4282 T6126 T6124 arg2Of ability,retains
R4283 T6126 T6125 arg1Of ability,the
R4284 T6126 T6127 modOf ability,to
R4285 T6128 T6127 arg1Of repress,to
R4286 T6131 T6128 arg2Of promoter,repress
R4287 T6131 T6129 arg1Of promoter,the
R4288 T6131 T6130 arg1Of promoter,ɛy
R4289 T6131 T6132 arg1Of promoter,in
R4290 T6135 T6132 arg2Of assay,in
R4291 T6135 T6133 arg1Of assay,the
R4292 T6135 T6134 arg1Of assay,transfection
R4293 T6135 T6136 arg1Of assay,(
R4294 T6138 T6136 arg2Of 2B,(
R4295 T6138 T6137 arg1Of 2B,Figure
R4296 T6139 T6136 arg3Of ),(
R4297 T6143 T6144 arg1Of Sox6,represses
R4298 T6144 T6141 arg2Of represses,indicating
R4299 T6144 T6142 arg1Of represses,that
R4300 T6144 T6148 arg1Of represses,in
R4301 T6147 T6144 arg2Of promoter,represses
R4302 T6147 T6145 arg1Of promoter,the
R4303 T6147 T6146 arg1Of promoter,ɛy
R4304 T6151 T6148 arg2Of manner,in
R4305 T6151 T6149 arg1Of manner,a
R4306 T6151 T6150 arg1Of manner,CtBP2-independent
R4307 T6153 T6152 arg1Of analysis,Deletion
R4308 T6153 T6154 arg1Of analysis,of
R4309 T6153 T6165 arg1Of analysis,defined
R4310 T6157 T6154 arg2Of promoter,of
R4311 T6157 T6155 arg1Of promoter,the
R4312 T6157 T6156 arg1Of promoter,ɛy
R4313 T6160 T6159 arg2Of shown,as
R4314 T6160 T6161 arg1Of shown,in
R4315 T6163 T6161 arg2Of 2C,in
R4316 T6163 T6162 arg1Of 2C,Figure
R4317 T6165 T6158 arg1Of defined,","
R4318 T6165 T6159 arg1Of defined,as
R4319 T6165 T6164 arg1Of defined,","
R4320 T6167 T6165 arg2Of region,defined
R4321 T6167 T6166 arg1Of region,a
R4322 T6167 T6168 arg1Of region,(
R4323 T6167 T6173 arg1Of region,within
R4324 T6171 T6168 arg2Of −37,(
R4325 T6171 T6169 arg1Of −37,−63
R4326 T6171 T6170 arg1Of −37,to
R4327 T6172 T6168 arg3Of ),(
R4328 T6177 T6173 arg2Of promoter,within
R4329 T6177 T6174 arg1Of promoter,the
R4330 T6177 T6175 arg1Of promoter,ɛy
R4331 T6177 T6176 arg1Of promoter,proximal
R4332 T6177 T6178 arg1Of promoter,that
R4333 T6177 T6179 arg1Of promoter,is
R4334 T6177 T6180 arg1Of promoter,critical
R4335 T6180 T6179 arg2Of critical,is
R4336 T6180 T6181 arg1Of critical,for
R4337 T6183 T6181 arg2Of repression,for
R4338 T6183 T6182 arg1Of repression,Sox6
R4339 T6184 T6185 arg1Of Analysis,of
R4340 T6184 T6189 arg1Of Analysis,reveals
R4341 T6188 T6185 arg2Of region,of
R4342 T6188 T6186 arg1Of region,this
R4343 T6188 T6187 arg1Of region,short
R4344 T6194 T6189 arg2Of sites,reveals
R4345 T6194 T6190 arg1Of sites,two
R4346 T6194 T6191 arg1Of sites,Sox/Sox6
R4347 T6194 T6192 arg1Of sites,consensus
R4348 T6194 T6193 arg1Of sites,binding
R4349 T6194 T6195 arg1Of sites,[
R4350 T6194 T6198 arg1Of sites,(
R4351 T6196 T6195 arg2Of 5,[
R4352 T6197 T6195 arg3Of ],[
R4353 T6200 T6198 arg2Of 3A,(
R4354 T6200 T6199 arg1Of 3A,Figure
R4355 T6201 T6198 arg3Of ),(

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T5681 2800-2802 Protein denotes ɛy
T5680 2777-2781 Protein denotes Sox6
T5679 2755-2760 Protein denotes CtBP2
T5678 2657-2662 Protein denotes CtBP2
T5677 2637-2642 Protein denotes fgf-3
T5676 2623-2628 Protein denotes CtBP2
T5675 2527-2531 Protein denotes Sox6
T5674 1104-1106 Protein denotes ɛy
T5673 1079-1083 Protein denotes Sox6
T5672 928-932 Protein denotes Sox6
T5671 760-764 Protein denotes Sox6
T5670 657-667 Protein denotes luciferase
T5669 610-612 Protein denotes ɛy
T5668 513-515 Protein denotes ɛy
T5667 478-490 Protein denotes beta globins
T5666 465-467 Protein denotes ɛy
T5665 297-299 Protein denotes ɛy
T5664 271-275 Protein denotes Sox6
T5663 235-237 Protein denotes ɛy
T5662 190-192 Protein denotes ɛy
T5661 81-83 Protein denotes ɛy
T5660 53-57 Protein denotes Sox6
T5692 3368-3372 Protein denotes Sox6
T5691 3326-3328 Protein denotes ɛy
T5690 3249-3251 Protein denotes ɛy
T5689 3198-3203 Protein denotes CtBP2
T5688 3181-3183 Protein denotes ɛy
T5687 3162-3166 Protein denotes Sox6
T5686 3095-3097 Protein denotes ɛy
T5685 3055-3059 Protein denotes Sox6
T5684 2939-2944 Protein denotes CtBP2
T5683 2934-2938 Protein denotes Sox6
T5682 2859-2863 Protein denotes Sox6

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T6220 3198-3203 http://www.uniprot.org/uniprot/P56545 denotes CtBP2
T6219 2939-2944 http://www.uniprot.org/uniprot/P56545 denotes CtBP2
T6218 2755-2760 http://www.uniprot.org/uniprot/P56545 denotes CtBP2
T6217 2657-2662 http://www.uniprot.org/uniprot/P56545 denotes CtBP2
T6216 2623-2628 http://www.uniprot.org/uniprot/P56545 denotes CtBP2
T6212 3162-3166 http://www.uniprot.org/uniprot/P35712 denotes Sox6
T6211 3055-3059 http://www.uniprot.org/uniprot/P35712 denotes Sox6
T6210 2934-2938 http://www.uniprot.org/uniprot/P35712 denotes Sox6
T6209 2859-2863 http://www.uniprot.org/uniprot/P35712 denotes Sox6
T6208 2777-2781 http://www.uniprot.org/uniprot/P35712 denotes Sox6
T6207 2527-2531 http://www.uniprot.org/uniprot/P35712 denotes Sox6
T6206 1079-1083 http://www.uniprot.org/uniprot/P35712 denotes Sox6
T6205 928-932 http://www.uniprot.org/uniprot/P35712 denotes Sox6
T6204 760-764 http://www.uniprot.org/uniprot/P35712 denotes Sox6
T6203 271-275 http://www.uniprot.org/uniprot/P35712 denotes Sox6
T6202 53-57 http://www.uniprot.org/uniprot/P35712 denotes Sox6
T6215 657-667 http://www.uniprot.org/uniprot/P08659 denotes luciferase
T6214 3431-3435 http://www.uniprot.org/uniprot/P35712 denotes Sox6
T6213 3368-3372 http://www.uniprot.org/uniprot/P35712 denotes Sox6

GO-BP

Id Subject Object Predicate Lexical cue
T5610 483-490 http://purl.obolibrary.org/obo/GO_0005344 denotes globins
T5609 1123-1138 http://purl.obolibrary.org/obo/GO_0006351 denotes transcriptional
T5608 321-336 http://purl.obolibrary.org/obo/GO_0006351 denotes transcriptional
T5607 203-218 http://purl.obolibrary.org/obo/GO_0006351 denotes transcriptional
T5606 193-218 http://purl.obolibrary.org/obo/GO_0009299 denotes mRNA, not transcriptional

GO-MF

Id Subject Object Predicate Lexical cue
T5697 3446-3453 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T5696 3007-3014 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T5695 3003-3021 http://purl.obolibrary.org/obo/GO_0050692 denotes DNA binding domain
T5694 3003-3014 http://purl.obolibrary.org/obo/GO_0003677 denotes DNA binding
T5693 483-490 http://purl.obolibrary.org/obo/GO_0005344 denotes globins

GO-CC

Id Subject Object Predicate Lexical cue
T5700 2685-2690 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T5699 774-779 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T5698 403-408 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

sentences

Id Subject Object Predicate Lexical cue
T5605 3385-3476 Sentence denotes Analysis of this short region reveals two Sox/Sox6 consensus binding sites [5] (Figure 3A).
T5604 3224-3384 Sentence denotes Deletion analysis of the ɛy promoter, as shown in Figure 2C, defined a region (−63 to −37) within the ɛy proximal promoter that is critical for Sox6 repression.
T5603 3023-3223 Sentence denotes However, this mutant version of Sox6 retains the ability to repress the ɛy promoter in the transfection assay (Figure 2B), indicating that Sox6 represses the ɛy promoter in a CtBP2-independent manner.
T5602 2962-3022 Sentence denotes This amino acid change is not in the HMG DNA binding domain.
T5601 2711-2961 Sentence denotes To investigate whether the interaction with CtBP2 is required for Sox6 repression of the ɛy promoter, we introduced a point mutation (L386H) in the Sox6 protein that has been previously reported to be sufficient to abolish Sox6-CtBP2 interaction [5].
T5600 2657-2710 Sentence denotes CtBP2 is expressed in GM979 cells (unpublished data).
T5599 2527-2656 Sentence denotes Sox6 has been shown to act as a repressor and to interact with a widely expressed co-repressor, CtBP2, on the fgf-3 promoter [5].
T5598 1054-1145 Sentence denotes These data indicate that Sox6 acts to repress the ɛy promoter at the transcriptional level.
T5597 885-1053 Sentence denotes In contrast, overexpression of a truncated Sox6 protein that lacks its HMG domain [32] (similar to the p 100H mouse allele) fails to repress E-Luc activity (Figure 2B).
T5596 742-884 Sentence denotes Overexpression of Sox6 in GM979 cells by transient transfection leads to a dosage-dependent repression of E-Luc reporter activity (Figure 2B).
T5595 497-741 Sentence denotes We generated an ɛy promoter reporter construct (E-Luc) by fusing a micro-LCR (μLCR) element (2.5 kb) [31] to the ɛy proximal promoter (2.2 kb), followed by the luciferase reporter gene, as shown in Figure 2A (detailed in Materials and Methods).
T5594 248-496 Sentence denotes To investigate whether Sox6 directly acts on the ɛy gene promoter at the transcriptional level, we used an in vitro transient transfection assay and GM979 cells, a murine erythroleukemic cell line that expresses both ɛy and adult beta globins [30].
T5593 127-247 Sentence denotes Real-time PCR assays (Figure 1) measure steady-state levels of ɛy mRNA, not transcriptional activity of the ɛy promoter.
T5592 0-126 Sentence denotes Transfection Studies Using GM979 Cells Indicate That Sox6 Directly Represses the ɛy Gene Promoter at the Transcriptional Level
T72 0-126 Sentence denotes Transfection Studies Using GM979 Cells Indicate That Sox6 Directly Represses the ɛy Gene Promoter at the Transcriptional Level
T73 127-247 Sentence denotes Real-time PCR assays (Figure 1) measure steady-state levels of ɛy mRNA, not transcriptional activity of the ɛy promoter.
T74 248-496 Sentence denotes To investigate whether Sox6 directly acts on the ɛy gene promoter at the transcriptional level, we used an in vitro transient transfection assay and GM979 cells, a murine erythroleukemic cell line that expresses both ɛy and adult beta globins [30].
T75 497-741 Sentence denotes We generated an ɛy promoter reporter construct (E-Luc) by fusing a micro-LCR (μLCR) element (2.5 kb) [31] to the ɛy proximal promoter (2.2 kb), followed by the luciferase reporter gene, as shown in Figure 2A (detailed in Materials and Methods).
T76 742-884 Sentence denotes Overexpression of Sox6 in GM979 cells by transient transfection leads to a dosage-dependent repression of E-Luc reporter activity (Figure 2B).
T77 885-1053 Sentence denotes In contrast, overexpression of a truncated Sox6 protein that lacks its HMG domain [32] (similar to the p 100H mouse allele) fails to repress E-Luc activity (Figure 2B).
T78 1054-1145 Sentence denotes These data indicate that Sox6 acts to repress the ɛy promoter at the transcriptional level.
T79 1146-1193 Sentence denotes Figure 2 The Effect of Sox6 on the ɛy Promoter
T80 1194-1276 Sentence denotes (A) Constructs of the ɛy promoter reporter (E-luc) and Sox6 overexpression vector.
T81 1277-1455 Sentence denotes The E-luc reporter construct consists of a 2.5-kb μLCR element, a 2.2-kb ɛy proximal promoter, and the luciferase reporter in the pGL-3 basic plasmid (see Materials and Methods).
T82 1456-1502 Sentence denotes Sox6 expression is driven by the CMV promoter.
T83 1503-1572 Sentence denotes (B) Sox6 represses ɛy promoter activity in a dosage-dependent manner.
T84 1573-1999 Sentence denotes In GM979 cells, the E-Luc ɛy promoter reporter construct was co-transfected (1) without overexpression of Sox6; (2–4) with increasing amounts of CMV-Sox6 overexpression vector; (5) with a truncated version of Sox6 that lacks its HMG domain; (6) with a mutant version of Sox6 (L386H) that has previously been shown to abolish interaction with CtBP2; or (7) with an empty reporter plasmid (without ɛy promoter and μLCR element).
T85 2000-2064 Sentence denotes (C) Promoter deletion analyses to delimit the critical sequence.
T86 2065-2390 Sentence denotes The 2.2-kb proximal promoter or deletions of it, as indicated on the left (numbering relative to +1 = the transcription start site of ɛy globin, see Materials and Methods), were engineered in reporter constructs as in (A) and were transfected along with CMV driven Sox6 to GM979 cells (see Materials and Methods for details).
T87 2391-2485 Sentence denotes The relative repression by Sox6 on the activity of the different reporter constructs is shown.
T88 2486-2526 Sentence denotes All experiments were done in triplicate.
T89 2527-2656 Sentence denotes Sox6 has been shown to act as a repressor and to interact with a widely expressed co-repressor, CtBP2, on the fgf-3 promoter [5].
T90 2657-2710 Sentence denotes CtBP2 is expressed in GM979 cells (unpublished data).
T91 2711-2961 Sentence denotes To investigate whether the interaction with CtBP2 is required for Sox6 repression of the ɛy promoter, we introduced a point mutation (L386H) in the Sox6 protein that has been previously reported to be sufficient to abolish Sox6-CtBP2 interaction [5].
T92 2962-3022 Sentence denotes This amino acid change is not in the HMG DNA binding domain.
T93 3023-3223 Sentence denotes However, this mutant version of Sox6 retains the ability to repress the ɛy promoter in the transfection assay (Figure 2B), indicating that Sox6 represses the ɛy promoter in a CtBP2-independent manner.
T94 3224-3384 Sentence denotes Deletion analysis of the ɛy promoter, as shown in Figure 2C, defined a region (−63 to −37) within the ɛy proximal promoter that is critical for Sox6 repression.
T95 3385-3476 Sentence denotes Analysis of this short region reveals two Sox/Sox6 consensus binding sites [5] (Figure 3A).
T96 3477-3572 Sentence denotes Figure 3 Analysis of the Minimal Region (36 bp) of the Proximal ɛy Promoter Responsive to Sox6
T97 3573-3649 Sentence denotes (A) The sequence of the 36-bp fragment and its mutant versions used in EMSA.
T98 3650-3795 Sentence denotes The WT 36-bp DNA sequence (−63 to −28) of the ɛy globin proximal promoter contains two Sox/Sox6 consensus binding sites, shown in bold underline.
T99 3796-3924 Sentence denotes Versions with truncation of this sequence (M1) or mutation of one of the two consensus binding sites (M2 and M3) are also shown.
T100 3925-3957 Sentence denotes (B) EMSA with c-Myc-tagged Sox6.
T101 3958-4130 Sentence denotes EMSA was performed using the 36-bp radio-labeled WT probe (as shown in (A)) and c-Myc tagged Sox6 translated in vitro using reticulocyte lysate (see Materials and Methods).
T102 4131-4516 Sentence denotes Lane 1: radio-labeled free probe (run out of the gel); Lane 2: no competition, no antibody; Lane 3: competition with 200-fold excess cold probe, no antibody; Lane 4: no competition, c-Myc antibody (producing a supershift); Lane 5: no competition, Sox6 antibody (producing a supershift); Lane 6: no competion, no antibody using in vitro translated vector containing c-Myc, but not Sox6.
T103 4517-4546 Sentence denotes (C) EMSA with HA-tagged Sox6.
T104 4547-4627 Sentence denotes EMSA was performed similarly as in (B) using HA-tagged Sox6 translated in vitro.
T105 4628-4847 Sentence denotes Lane 1: radio-labeled free probe (run out of the gel); Lane 2: no competition, no antibody; Lane 3: competition with 200-fold excess cold probe, no antibody; Lane 4: no competition, HA antibody (producing a supershift).
T106 4848-4912 Sentence denotes (D) EMSA using MEL cell nuclear extracts and the 36-bp WT probe.
T107 4913-5134 Sentence denotes Lane 1: radio-labeled free probe (run out of the gel); Lane 2: no competition, no antibody; Lane 3: competition with 200-fold excess cold probe, no antibody; Lane 4: no competition, Sox6 antibody (producing a supershift).
T108 5135-5228 Sentence denotes (E) EMSA with c-Myc-tagged Sox6, WT and mutant versions of the 36-bp fragment in competition.
T109 5229-5333 Sentence denotes EMSA was performed using the radio-labeled 36-bp WT probe and the c-Myc tagged Sox6 translated in vitro.
T110 5334-5404 Sentence denotes Lane 1: radio-labeled free probe; Lane 2: no competition, no antibody.
T111 5405-5537 Sentence denotes Competition was performed using 200-fold excess cold probes corresponding to WT (Lane 3), M1 (Lane 4), M2 (Lane 5), and M3 (Lane 6).
T112 5538-5617 Sentence denotes (F) Both consensus Sox/Sox6 binding sites are required for Sox6 responsiveness.
T113 5618-5784 Sentence denotes GM979 cells were transfected with a reporter construct (Figure 2A) containing −63 to +45 of the ɛy proximal promoter together with the CMV-Sox6 overexpression vector.
T114 5785-5873 Sentence denotes Mutations of the consensus binding sites were also tested (M3, M2, M2 plus M3, see (A)).
T115 5874-5944 Sentence denotes The fold repression of Sox6 with the WT or mutant constructs is shown.
T116 5945-6043 Sentence denotes The baseline activities of the mutagenized reporter constructs are comparable to the WT construct.

simple1

Id Subject Object Predicate Lexical cue
T5815 3368-3372 Protein denotes Sox6
T5814 3326-3328 Protein denotes ɛy
T5813 3249-3251 Protein denotes ɛy
T5812 3198-3203 Protein denotes CtBP2
T5811 3181-3183 Protein denotes ɛy
T5810 3162-3166 Protein denotes Sox6
T5809 3095-3097 Protein denotes ɛy
T5808 3055-3059 Protein denotes Sox6
T5807 2939-2944 Protein denotes CtBP2
T5806 2934-2938 Protein denotes Sox6
T5805 2859-2863 Protein denotes Sox6
T5804 2800-2802 Protein denotes ɛy
T5803 2777-2781 Protein denotes Sox6
T5802 2755-2760 Protein denotes CtBP2
T5801 2657-2662 Protein denotes CtBP2
T5800 2637-2642 Protein denotes fgf-3
T5799 2623-2628 Protein denotes CtBP2
T5798 2527-2531 Protein denotes Sox6
T5797 1104-1106 Protein denotes ɛy
T5796 1079-1083 Protein denotes Sox6
T5795 928-932 Protein denotes Sox6
T5794 760-764 Protein denotes Sox6
T5793 657-667 Protein denotes luciferase
T5792 610-612 Protein denotes ɛy
T5791 513-515 Protein denotes ɛy
T5790 478-490 Protein denotes beta globins
T5789 465-467 Protein denotes ɛy
T5788 297-299 Protein denotes ɛy
T5787 271-275 Protein denotes Sox6
T5786 235-237 Protein denotes ɛy
T5785 190-192 Protein denotes ɛy
T5784 81-83 Protein denotes ɛy
T5783 53-57 Protein denotes Sox6

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T6932 3373-3383 Negative_regulation denotes repression
T6931 3167-3176 Negative_regulation denotes represses
T6930 3083-3090 Negative_regulation denotes repress
T6929 2738-2749 Binding denotes interaction
T6928 2782-2792 Negative_regulation denotes repression
T6927 2945-2956 Binding denotes interaction
T6926 2926-2933 Negative_regulation denotes abolish
T6925 2764-2772 Positive_regulation denotes required
T6924 2666-2675 Gene_expression denotes expressed
T6923 2599-2608 Gene_expression denotes expressed
T6922 2576-2584 Binding denotes interact
T6921 1092-1099 Negative_regulation denotes repress
T6920 898-912 Gene_expression denotes overexpression
T6919 898-912 Positive_regulation denotes overexpression
T6918 742-756 Positive_regulation denotes Overexpression
T6917 742-756 Gene_expression denotes Overexpression
T6916 285-289 Positive_regulation denotes acts
T6915 450-459 Gene_expression denotes expresses
T6914 3368-3372 Protein denotes Sox6
T6913 3326-3328 Protein denotes ɛy
T6912 3249-3251 Protein denotes ɛy
T6911 3198-3203 Protein denotes CtBP2
T6910 3181-3183 Protein denotes ɛy
T6909 3162-3166 Protein denotes Sox6
T6908 3095-3097 Protein denotes ɛy
T6907 3055-3059 Protein denotes Sox6
T6906 2939-2944 Protein denotes CtBP2
T6905 2934-2938 Protein denotes Sox6
T6904 2859-2863 Protein denotes Sox6
T6903 2800-2802 Protein denotes ɛy
T6902 2777-2781 Protein denotes Sox6
T6901 2755-2760 Protein denotes CtBP2
T6900 2657-2662 Protein denotes CtBP2
T6899 2637-2642 Protein denotes fgf-3
T6898 2623-2628 Protein denotes CtBP2
T6897 2527-2531 Protein denotes Sox6
T6896 1104-1106 Protein denotes ɛy
T6895 1079-1083 Protein denotes Sox6
T6894 928-932 Protein denotes Sox6
T6893 760-764 Protein denotes Sox6
T6892 513-515 Protein denotes ɛy
T6891 657-667 Protein denotes luciferase
T6890 610-612 Protein denotes ɛy
T6889 478-490 Protein denotes beta globins
T6888 465-467 Protein denotes ɛy
T6887 297-299 Protein denotes ɛy
T6886 271-275 Protein denotes Sox6
T6885 235-237 Protein denotes ɛy
T6884 190-192 Protein denotes ɛy
T6883 81-83 Protein denotes ɛy
T6882 53-57 Protein denotes Sox6
R4864 T6886 T6916 causeOf Sox6,acts
R4865 T6887 T6916 themeOf ɛy,acts
R4866 T6888 T6915 themeOf ɛy,expresses
R4867 T6889 T6915 themeOf beta globins,expresses
R4868 T6893 T6917 themeOf Sox6,Overexpression
R4869 T6894 T6920 themeOf Sox6,overexpression
R4870 T6895 T6921 causeOf Sox6,repress
R4871 T6896 T6921 themeOf ɛy,repress
R4872 T6898 T6922 themeOf CtBP2,interact
R4873 T6898 T6923 themeOf CtBP2,expressed
R4874 T6899 T6922 themeOf fgf-3,interact
R4875 T6899 T6923 themeOf fgf-3,expressed
R4876 T6900 T6924 themeOf CtBP2,expressed
R4877 T6901 T6929 themeOf CtBP2,interaction
R4878 T6902 T6928 themeOf Sox6,repression
R4879 T6903 T6928 themeOf ɛy,repression
R4880 T6905 T6927 themeOf Sox6,interaction
R4881 T6906 T6927 themeOf CtBP2,interaction
R4882 T6907 T6930 causeOf Sox6,repress
R4883 T6908 T6930 themeOf ɛy,repress
R4884 T6909 T6931 causeOf Sox6,represses
R4885 T6910 T6931 themeOf ɛy,represses
R4886 T6914 T6932 themeOf Sox6,repression
R4887 T6917 T6918 themeOf Overexpression,Overexpression
R4888 T6920 T6919 themeOf overexpression,overexpression
R4889 T6927 T6926 themeOf interaction,abolish
R4890 T6927 T6926 themeOf interaction,abolish
R4891 T6928 T6925 themeOf repression,required
R4892 T6928 T6925 themeOf repression,required
R4893 T6929 T6925 causeOf interaction,required
R4894 T6929 T6925 causeOf interaction,required

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T6270 3373-3383 Negative_regulation denotes repression
T6269 3083-3090 Negative_regulation denotes repress
T6268 3204-3215 Regulation denotes independent
T6267 3167-3176 Negative_regulation denotes represses
T6266 2738-2749 Binding denotes interaction
T6265 2945-2956 Binding denotes interaction
T6264 2764-2772 Positive_regulation denotes required
T6263 2926-2933 Negative_regulation denotes abolish
T6262 2782-2792 Negative_regulation denotes repression
T6261 2666-2675 Gene_expression denotes expressed
T6260 2599-2608 Gene_expression denotes expressed
T6259 2576-2584 Binding denotes interact
T6258 1092-1099 Negative_regulation denotes repress
T6257 898-912 Positive_regulation denotes overexpression
T6256 742-756 Positive_regulation denotes Overexpression
T6255 285-289 Binding denotes acts
T6254 450-459 Gene_expression denotes expresses
T6253 3368-3372 Protein denotes Sox6
T6228 478-490 Protein denotes beta globins
T6227 465-467 Protein denotes ɛy
T6226 297-299 Protein denotes ɛy
T6225 271-275 Protein denotes Sox6
T6224 235-237 Protein denotes ɛy
T6223 190-192 Protein denotes ɛy
T6222 81-83 Protein denotes ɛy
T6221 53-57 Protein denotes Sox6
T6252 3326-3328 Protein denotes ɛy
T6251 3249-3251 Protein denotes ɛy
T6250 3198-3203 Protein denotes CtBP2
T6249 3181-3183 Protein denotes ɛy
T6248 3162-3166 Protein denotes Sox6
T6247 3095-3097 Protein denotes ɛy
T6246 3055-3059 Protein denotes Sox6
T6245 2939-2944 Protein denotes CtBP2
T6244 2934-2938 Protein denotes Sox6
T6243 2859-2863 Protein denotes Sox6
T6242 2800-2802 Protein denotes ɛy
T6241 2777-2781 Protein denotes Sox6
T6240 2755-2760 Protein denotes CtBP2
T6239 2657-2662 Protein denotes CtBP2
T6238 2637-2642 Protein denotes fgf-3
T6237 2623-2628 Protein denotes CtBP2
T6236 2527-2531 Protein denotes Sox6
T6235 1104-1106 Protein denotes ɛy
T6234 1079-1083 Protein denotes Sox6
T6233 928-932 Protein denotes Sox6
T6232 760-764 Protein denotes Sox6
T6231 513-515 Protein denotes ɛy
T6230 657-667 Protein denotes luciferase
T6229 610-612 Protein denotes ɛy
R4356 T6225 T6255 themeOf Sox6,acts
R4357 T6227 T6254 themeOf ɛy,expresses
R4358 T6232 T6256 themeOf Sox6,Overexpression
R4359 T6233 T6257 themeOf Sox6,overexpression
R4360 T6234 T6258 causeOf Sox6,repress
R4361 T6235 T6258 themeOf ɛy,repress
R4362 T6236 T6259 themeOf Sox6,interact
R4363 T6236 T6259 themeOf Sox6,interact
R4364 T6237 T6259 themeOf CtBP2,interact
R4365 T6237 T6260 themeOf CtBP2,expressed
R4366 T6238 T6259 themeOf fgf-3,interact
R4367 T6238 T6260 themeOf fgf-3,expressed
R4368 T6239 T6261 themeOf CtBP2,expressed
R4369 T6240 T6266 themeOf CtBP2,interaction
R4370 T6241 T6262 themeOf Sox6,repression
R4371 T6244 T6265 themeOf Sox6,interaction
R4372 T6245 T6265 themeOf CtBP2,interaction
R4373 T6247 T6269 themeOf ɛy,repress
R4374 T6248 T6267 causeOf Sox6,represses
R4375 T6249 T6267 themeOf ɛy,represses
R4376 T6250 T6268 themeOf CtBP2,independent
R4377 T6253 T6270 themeOf Sox6,repression
R4378 T6262 T6264 themeOf repression,required
R4379 T6265 T6263 themeOf interaction,abolish
R4380 T6265 T6263 themeOf interaction,abolish

DLUT931

Id Subject Object Predicate Lexical cue
T6322 3373-3383 Negative_regulation denotes repression
T6321 3204-3215 Regulation denotes independent
T6320 3167-3176 Negative_regulation denotes represses
T6319 3083-3090 Negative_regulation denotes repress
T6318 2926-2933 Negative_regulation denotes abolish
T6317 2764-2772 Positive_regulation denotes required
T6316 2945-2956 Binding denotes interaction
T6315 2835-2843 Regulation denotes mutation
T6314 2782-2792 Negative_regulation denotes repression
T6313 2738-2749 Binding denotes interaction
T6312 2666-2675 Gene_expression denotes expressed
T6311 2599-2608 Gene_expression denotes expressed
T6310 2576-2584 Binding denotes interact
T6309 1092-1099 Negative_regulation denotes repress
T6308 898-912 Positive_regulation denotes overexpression
T6307 742-756 Positive_regulation denotes Overexpression
T6306 450-459 Gene_expression denotes expresses
T6305 285-289 Positive_regulation denotes acts
T6304 67-76 Negative_regulation denotes Represses
T6303 3368-3372 Protein denotes Sox6
T6302 3326-3328 Protein denotes ɛy
T6301 3249-3251 Protein denotes ɛy
T6300 3198-3203 Protein denotes CtBP2
T6299 3181-3183 Protein denotes ɛy
T6298 3162-3166 Protein denotes Sox6
T6297 3095-3097 Protein denotes ɛy
T6296 3055-3059 Protein denotes Sox6
T6295 2939-2944 Protein denotes CtBP2
T6294 2934-2938 Protein denotes Sox6
T6293 2859-2863 Protein denotes Sox6
T6292 2800-2802 Protein denotes ɛy
T6291 2777-2781 Protein denotes Sox6
T6290 2755-2760 Protein denotes CtBP2
T6289 2657-2662 Protein denotes CtBP2
T6288 2637-2642 Protein denotes fgf-3
T6287 2623-2628 Protein denotes CtBP2
T6286 2527-2531 Protein denotes Sox6
T6285 1104-1106 Protein denotes ɛy
T6284 1079-1083 Protein denotes Sox6
T6283 928-932 Protein denotes Sox6
T6282 760-764 Protein denotes Sox6
T6281 513-515 Protein denotes ɛy
T6280 657-667 Protein denotes luciferase
T6279 610-612 Protein denotes ɛy
T6278 478-490 Protein denotes beta globins
T6277 465-467 Protein denotes ɛy
T6276 297-299 Protein denotes ɛy
T6275 271-275 Protein denotes Sox6
T6274 235-237 Protein denotes ɛy
T6273 190-192 Protein denotes ɛy
T6272 81-83 Protein denotes ɛy
T6271 53-57 Protein denotes Sox6
R4381 T6271 T6304 causeOf Sox6,Represses
R4382 T6272 T6304 themeOf ɛy,Represses
R4383 T6275 T6305 causeOf Sox6,acts
R4384 T6276 T6305 themeOf ɛy,acts
R4385 T6277 T6306 themeOf ɛy,expresses
R4386 T6278 T6306 themeOf beta globins,expresses
R4387 T6282 T6307 themeOf Sox6,Overexpression
R4388 T6283 T6308 themeOf Sox6,overexpression
R4389 T6284 T6309 causeOf Sox6,repress
R4390 T6285 T6309 themeOf ɛy,repress
R4391 T6286 T6310 themeOf Sox6,interact
R4392 T6286 T6310 themeOf Sox6,interact
R4393 T6287 T6310 themeOf CtBP2,interact
R4394 T6287 T6310 themeOf CtBP2,interact
R4395 T6288 T6311 themeOf fgf-3,expressed
R4396 T6288 T6310 themeOf fgf-3,interact
R4397 T6288 T6310 themeOf fgf-3,interact
R4398 T6289 T6312 themeOf CtBP2,expressed
R4399 T6290 T6313 themeOf CtBP2,interaction
R4400 T6291 T6314 themeOf Sox6,repression
R4401 T6292 T6314 themeOf ɛy,repression
R4402 T6293 T6315 themeOf Sox6,mutation
R4403 T6294 T6316 themeOf Sox6,interaction
R4404 T6295 T6316 themeOf CtBP2,interaction
R4405 T6297 T6319 themeOf ɛy,repress
R4406 T6298 T6320 causeOf Sox6,represses
R4407 T6299 T6320 themeOf ɛy,represses
R4408 T6300 T6321 causeOf CtBP2,independent
R4409 T6303 T6322 themeOf Sox6,repression
R4410 T6313 T6317 causeOf interaction,required
R4411 T6313 T6317 causeOf interaction,required
R4412 T6314 T6317 themeOf repression,required
R4413 T6314 T6317 themeOf repression,required
R4414 T6316 T6318 themeOf interaction,abolish
R4415 T6320 T6321 themeOf represses,independent

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T6881 2934-2960 Binding denotes Sox6-CtBP2 interaction [5]
T6880 2734-2760 Binding denotes the interaction with CtBP2
T6879 742-805 Gene_expression denotes Overexpression of Sox6 in GM979 cells by transient transfection
T6878 742-805 Positive_regulation denotes Overexpression of Sox6 in GM979 cells by transient transfection
T6877 2657-2709 Gene_expression denotes CtBP2 is expressed in GM979 cells (unpublished data)
T6876 3249-3251 Protein denotes ɛy
T6875 3242-3260 Entity denotes of the ɛy promoter
T6874 228-246 Entity denotes of the ɛy promoter
T6873 2793-2811 Entity denotes of the ɛy promoter
T6872 952-971 Entity denotes its HMG domain [32]
T6871 3368-3372 Protein denotes Sox6
T6870 3162-3166 Protein denotes Sox6
T6869 472-495 Protein denotes adult beta globins [30]
T6868 81-83 Protein denotes ɛy
T6867 293-313 Entity denotes the ɛy gene promoter
T6866 27-38 Entity denotes GM979 Cells
T6865 650-682 Protein denotes by the luciferase reporter gene,
T6864 2800-2802 Protein denotes ɛy
T6863 2527-2531 Protein denotes Sox6
T6862 2859-2863 Protein denotes Sox6
T6861 510-533 Entity denotes an ɛy promoter reporter
T6860 3198-3215 Protein denotes CtBP2-independent
T6859 575-579 Protein denotes μLCR
T6858 888-940 Protein denotes contrast, overexpression of a truncated Sox6 protein
T6857 190-198 Protein denotes ɛy mRNA,
T6856 1104-1106 Protein denotes ɛy
T6855 3055-3059 Protein denotes Sox6
T6854 397-409 Entity denotes GM979 cells,
T6853 2855-2911 Protein denotes the Sox6 protein that has been previously reported to be
T6852 606-639 Entity denotes the ɛy proximal promoter (2.2 kb)
T6851 1100-1115 Entity denotes the ɛy promoter
T6850 2633-2655 Entity denotes the fgf-3 promoter [5]
T6849 610-612 Protein denotes ɛy
T6848 2962-2977 Entity denotes This amino acid
T6847 513-515 Protein denotes ɛy
T6846 3177-3192 Entity denotes the ɛy promoter
T6845 981-1007 Protein denotes to the p 100H mouse allele
T6844 137-140 Protein denotes PCR
T6843 1079-1083 Protein denotes Sox6
T6842 2934-2960 Protein denotes Sox6-CtBP2 interaction [5]
T6841 2995-3021 Entity denotes the HMG DNA binding domain
T6840 2623-2628 Protein denotes CtBP2
T6839 757-764 Protein denotes of Sox6
T6838 3322-3346 Entity denotes the ɛy proximal promoter
T6837 3110-3144 Entity denotes the transfection assay (Figure 2B)
T6836 3091-3145 Entity denotes the ɛy promoter in the transfection assay (Figure 2B),
T6835 2939-2944 Protein denotes CtBP2
T6834 48-57 Protein denotes That Sox6
T6833 3181-3183 Protein denotes ɛy
T6832 3095-3097 Protein denotes ɛy
T6831 2679-2709 Entity denotes GM979 cells (unpublished data)
T6830 293-313 Protein denotes the ɛy gene promoter
T6829 2633-2655 Protein denotes the fgf-3 promoter [5]
T6828 657-667 Protein denotes luciferase
T6827 235-237 Protein denotes ɛy
T6826 3454-3463 Entity denotes sites [5]
T6825 2777-2781 Protein denotes Sox6
T6824 271-275 Protein denotes Sox6
T6823 190-192 Protein denotes ɛy
T6822 2657-2662 Protein denotes CtBP2
T6821 3326-3328 Protein denotes ɛy
T6820 77-126 Entity denotes the ɛy Gene Promoter at the Transcriptional Level
T6819 3423-3445 Protein denotes two Sox/Sox6 consensus
T6818 465-467 Protein denotes ɛy
T6817 928-932 Protein denotes Sox6
T6816 297-299 Protein denotes ɛy
T6815 77-126 Protein denotes the ɛy Gene Promoter at the Transcriptional Level
T6814 768-805 Entity denotes GM979 cells by transient transfection
T6813 2750-2760 Protein denotes with CtBP2
R4850 T6813 T6880 themeOf with CtBP2,the interaction with CtBP2
R4851 T6822 T6877 themeOf CtBP2,CtBP2 is expressed in GM979 cells (unpublished data)
R4852 T6835 T6881 themeOf CtBP2,Sox6-CtBP2 interaction [5]
R4853 T6836 T6832 partOf "the ɛy promoter in the transfection assay (Figure 2B),",ɛy
R4854 T6838 T6821 partOf the ɛy proximal promoter,ɛy
R4855 T6839 T6878 themeOf of Sox6,Overexpression of Sox6 in GM979 cells by transient transfection
R4856 T6839 T6879 themeOf of Sox6,Overexpression of Sox6 in GM979 cells by transient transfection
R4857 T6846 T6833 partOf the ɛy promoter,ɛy
R4858 T6850 T6829 partOf the fgf-3 promoter [5],the fgf-3 promoter [5]
R4859 T6851 T6856 partOf the ɛy promoter,ɛy
R4860 T6852 T6849 partOf the ɛy proximal promoter (2.2 kb),ɛy
R4861 T6873 T6864 partOf of the ɛy promoter,ɛy
R4862 T6874 T6827 partOf of the ɛy promoter,ɛy
R4863 T6875 T6876 partOf of the ɛy promoter,ɛy

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T6763 3475-3476 . denotes .
T6762 3474-3475 -RRB- denotes )
T6761 3472-3474 NNP denotes 3A
T6760 3465-3471 NNP denotes Figure
T6759 3464-3465 -LRB- denotes (
T6758 3462-3463 NNP denotes ]
T6757 3461-3462 CD denotes 5
T6756 3460-3461 VBP denotes [
T6755 3454-3459 NNS denotes sites
T6754 3446-3453 JJ denotes binding
T6753 3436-3445 NN denotes consensus
T6752 3427-3435 JJ denotes Sox/Sox6
T6751 3423-3426 CD denotes two
T6750 3415-3422 VBZ denotes reveals
T6749 3408-3414 NN denotes region
T6748 3402-3407 JJ denotes short
T6747 3397-3401 DT denotes this
T6746 3394-3396 IN denotes of
T6745 3385-3393 NN denotes Analysis
T6744 3383-3384 . denotes .
T6743 3373-3383 NN denotes repression
T6742 3368-3372 JJ denotes Sox6
T6741 3364-3367 IN denotes for
T6740 3355-3363 JJ denotes critical
T6739 3352-3354 VBZ denotes is
T6738 3347-3351 WDT denotes that
T6737 3338-3346 NN denotes promoter
T6736 3329-3337 JJ denotes proximal
T6735 3326-3328 JJ denotes ɛy
T6734 3322-3325 DT denotes the
T6733 3315-3321 IN denotes within
T6732 3313-3314 -RRB- denotes )
T6731 3311-3313 CD denotes 37
T6730 3310-3311 CD denotes −
T6729 3307-3309 TO denotes to
T6728 3304-3306 CD denotes 63
T6727 3303-3304 FW denotes −
T6726 3302-3303 -LRB- denotes (
T6725 3295-3301 NN denotes region
T6724 3293-3294 DT denotes a
T6723 3285-3292 VBD denotes defined
T6722 3283-3284 , denotes ,
T6721 3281-3283 CD denotes 2C
T6720 3274-3280 NN denotes Figure
T6719 3271-3273 IN denotes in
T6718 3265-3270 VBN denotes shown
T6717 3262-3264 IN denotes as
T6716 3260-3261 , denotes ,
T6715 3252-3260 NN denotes promoter
T6714 3249-3251 JJ denotes ɛy
T6713 3245-3248 DT denotes the
T6712 3242-3244 IN denotes of
T6711 3233-3241 NN denotes analysis
T6710 3224-3232 NN denotes Deletion
T6709 3222-3223 . denotes .
T6708 3216-3222 NN denotes manner
T6707 3198-3215 JJ denotes CtBP2-independent
T6706 3196-3197 DT denotes a
T6705 3193-3195 IN denotes in
T6704 3184-3192 NN denotes promoter
T6703 3181-3183 JJ denotes ɛy
T6702 3177-3180 DT denotes the
T6701 3167-3176 NNS denotes represses
T6700 3162-3166 JJ denotes Sox6
T6699 3157-3161 IN denotes that
T6698 3146-3156 VBG denotes indicating
T6697 3144-3145 , denotes ,
T6696 3143-3144 -RRB- denotes )
T6695 3141-3143 NN denotes 2B
T6694 3134-3140 NN denotes Figure
T6693 3133-3134 -LRB- denotes (
T6692 3127-3132 NN denotes assay
T6691 3114-3126 NN denotes transfection
T6690 3110-3113 DT denotes the
T6689 3107-3109 IN denotes in
T6688 3098-3106 NN denotes promoter
T6687 3095-3097 JJ denotes ɛy
T6686 3091-3094 DT denotes the
T6685 3083-3090 VB denotes repress
T6684 3080-3082 TO denotes to
T6683 3072-3079 NN denotes ability
T6682 3068-3071 DT denotes the
T6681 3060-3067 VBZ denotes retains
T6680 3055-3059 JJ denotes Sox6
T6679 3052-3054 IN denotes of
T6678 3044-3051 NN denotes version
T6677 3037-3043 JJ denotes mutant
T6676 3032-3036 DT denotes this
T6675 3030-3031 , denotes ,
T6674 3023-3030 RB denotes However
T6673 3021-3022 . denotes .
T6672 3015-3021 NN denotes domain
T6671 3007-3014 JJ denotes binding
T6670 3003-3006 NNP denotes DNA
T6669 2999-3002 NNP denotes HMG
T6668 2995-2998 DT denotes the
T6667 2992-2994 IN denotes in
T6666 2988-2991 RB denotes not
T6665 2985-2987 VBZ denotes is
T6664 2978-2984 NN denotes change
T6663 2973-2977 NN denotes acid
T6662 2967-2972 JJ denotes amino
T6661 2962-2966 DT denotes This
T6660 2960-2961 . denotes .
T6659 2959-2960 NNP denotes ]
T6658 2958-2959 CD denotes 5
T6657 2957-2958 NN denotes [
T6656 2945-2956 NN denotes interaction
T6655 2934-2944 JJ denotes Sox6-CtBP2
T6654 2926-2933 VB denotes abolish
T6653 2923-2925 TO denotes to
T6652 2912-2922 JJ denotes sufficient
T6651 2909-2911 VB denotes be
T6650 2906-2908 TO denotes to
T6649 2897-2905 VBN denotes reported
T6648 2886-2896 RB denotes previously
T6647 2881-2885 VBN denotes been
T6646 2877-2880 VBZ denotes has
T6645 2872-2876 WDT denotes that
T6644 2864-2871 NN denotes protein
T6643 2859-2863 JJ denotes Sox6
T6642 2855-2858 DT denotes the
T6641 2852-2854 IN denotes in
T6640 2850-2851 -RRB- denotes )
T6639 2845-2850 NNP denotes L386H
T6638 2844-2845 -LRB- denotes (
T6637 2835-2843 NN denotes mutation
T6636 2829-2834 NN denotes point
T6635 2827-2828 DT denotes a
T6634 2816-2826 VBD denotes introduced
T6633 2813-2815 PRP denotes we
T6632 2811-2812 , denotes ,
T6631 2803-2811 NN denotes promoter
T6630 2800-2802 JJ denotes ɛy
T6629 2796-2799 DT denotes the
T6628 2793-2795 IN denotes of
T6627 2782-2792 NN denotes repression
T6626 2777-2781 JJ denotes Sox6
T6625 2773-2776 IN denotes for
T6624 2764-2772 VBN denotes required
T6623 2761-2763 VBZ denotes is
T6622 2755-2760 NNP denotes CtBP2
T6621 2750-2754 IN denotes with
T6620 2738-2749 NN denotes interaction
T6619 2734-2737 DT denotes the
T6618 2726-2733 IN denotes whether
T6617 2714-2725 VB denotes investigate
T6616 2711-2713 TO denotes To
T6615 2709-2710 . denotes .
T6614 2708-2709 -RRB- denotes )
T6613 2704-2708 NNS denotes data
T6612 2692-2703 JJ denotes unpublished
T6611 2691-2692 -LRB- denotes (
T6610 2685-2690 NNS denotes cells
T6609 2679-2684 NNP denotes GM979
T6608 2676-2678 IN denotes in
T6607 2666-2675 VBN denotes expressed
T6606 2663-2665 VBZ denotes is
T6605 2657-2662 NNP denotes CtBP2
T6604 2655-2656 . denotes .
T6603 2654-2655 NNP denotes ]
T6602 2653-2654 CD denotes 5
T6601 2652-2653 NN denotes [
T6600 2643-2651 NN denotes promoter
T6599 2637-2642 JJ denotes fgf-3
T6598 2633-2636 DT denotes the
T6597 2630-2632 IN denotes on
T6596 2628-2629 , denotes ,
T6595 2623-2628 NNP denotes CtBP2
T6594 2621-2622 , denotes ,
T6593 2609-2621 NN denotes co-repressor
T6592 2599-2608 VBN denotes expressed
T6591 2592-2598 RB denotes widely
T6590 2590-2591 DT denotes a
T6589 2585-2589 IN denotes with
T6588 2576-2584 VB denotes interact
T6587 2573-2575 TO denotes to
T6586 2569-2572 CC denotes and
T6585 2559-2568 NN denotes repressor
T6584 2557-2558 DT denotes a
T6583 2554-2556 IN denotes as
T6582 2550-2553 VB denotes act
T6581 2547-2549 TO denotes to
T6580 2541-2546 VBN denotes shown
T6579 2536-2540 VBN denotes been
T6578 2532-2535 VBZ denotes has
T6577 2527-2531 NNP denotes Sox6
T6576 1144-1145 . denotes .
T6575 1139-1144 NN denotes level
T6574 1123-1138 JJ denotes transcriptional
T6573 1119-1122 DT denotes the
T6572 1116-1118 IN denotes at
T6571 1107-1115 NN denotes promoter
T6570 1104-1106 JJ denotes ɛy
T6569 1100-1103 DT denotes the
T6447 495-496 . denotes .
T6446 494-495 NNP denotes ]
T6445 492-494 CD denotes 30
T6444 491-492 NNP denotes [
T6443 483-490 NNS denotes globins
T6442 478-482 JJ denotes beta
T6441 472-477 NN denotes adult
T6440 468-471 CC denotes and
T6439 465-467 NN denotes ɛy
T6438 460-464 DT denotes both
T6437 450-459 VBZ denotes expresses
T6436 445-449 WDT denotes that
T6435 440-444 NN denotes line
T6434 435-439 NN denotes cell
T6433 419-434 JJ denotes erythroleukemic
T6432 412-418 JJ denotes murine
T6431 410-411 DT denotes a
T6430 408-409 , denotes ,
T6429 403-408 NNS denotes cells
T6428 397-402 NNP denotes GM979
T6427 393-396 CC denotes and
T6426 387-392 NN denotes assay
T6425 374-386 NN denotes transfection
T6424 364-373 NN denotes transient
T6423 358-363 NN denotes vitro
T6422 355-357 IN denotes in
T6421 352-354 DT denotes an
T6420 347-351 VBD denotes used
T6419 344-346 PRP denotes we
T6418 342-343 , denotes ,
T6417 337-342 NN denotes level
T6416 321-336 JJ denotes transcriptional
T6415 317-320 DT denotes the
T6414 314-316 IN denotes at
T6413 305-313 NN denotes promoter
T6412 300-304 NN denotes gene
T6411 297-299 JJ denotes ɛy
T6410 293-296 DT denotes the
T6409 290-292 IN denotes on
T6408 285-289 VBZ denotes acts
T6407 276-284 RB denotes directly
T6406 271-275 JJ denotes Sox6
T6405 263-270 IN denotes whether
T6404 251-262 VB denotes investigate
T6403 248-250 TO denotes To
T6402 246-247 . denotes .
T6401 238-246 NN denotes promoter
T6400 235-237 JJ denotes ɛy
T6399 231-234 DT denotes the
T6398 228-230 IN denotes of
T6397 219-227 NN denotes activity
T6396 203-218 JJ denotes transcriptional
T6395 199-202 RB denotes not
T6394 197-198 , denotes ,
T6393 193-197 NNP denotes mRNA
T6392 190-192 JJ denotes ɛy
T6391 187-189 IN denotes of
T6390 180-186 NNS denotes levels
T6389 167-179 JJ denotes steady-state
T6388 159-166 NN denotes measure
T6387 157-158 -RRB- denotes )
T6386 156-157 CD denotes 1
T6385 149-155 NN denotes Figure
T6384 148-149 -LRB- denotes (
T6383 141-147 NNS denotes assays
T6382 137-140 NNP denotes PCR
T6381 127-136 JJ denotes Real-time
T6380 121-126 NNP denotes Level
T6379 105-120 NNP denotes Transcriptional
T6378 101-104 DT denotes the
T6377 98-100 IN denotes at
T6376 89-97 NNP denotes Promoter
T6375 84-88 NNP denotes Gene
T6374 81-83 NN denotes ɛy
T6373 77-80 DT denotes the
T6372 67-76 NNPS denotes Represses
T6371 58-66 RB denotes Directly
T6370 53-57 NNP denotes Sox6
T6369 48-52 WDT denotes That
T6368 39-47 NNP denotes Indicate
T6367 33-38 NNP denotes Cells
T6366 27-32 NNP denotes GM979
T6365 21-26 VBG denotes Using
T6364 13-20 NNP denotes Studies
T6363 0-12 NNP denotes Transfection
T6568 1092-1099 VB denotes repress
T6567 1089-1091 TO denotes to
T6566 1084-1088 NNS denotes acts
T6565 1079-1083 JJ denotes Sox6
T6564 1074-1078 IN denotes that
T6563 1065-1073 VBP denotes indicate
T6562 1060-1064 NNS denotes data
T6561 1054-1059 DT denotes These
T6560 1052-1053 . denotes .
T6559 1051-1052 -RRB- denotes )
T6558 1049-1051 NN denotes 2B
T6557 1042-1048 NN denotes Figure
T6556 1041-1042 -LRB- denotes (
T6555 1032-1040 NN denotes activity
T6554 1026-1031 JJ denotes E-Luc
T6553 1018-1025 VB denotes repress
T6552 1015-1017 TO denotes to
T6551 1009-1014 VBZ denotes fails
T6550 1007-1008 -RRB- denotes )
T6549 1001-1007 NN denotes allele
T6548 995-1000 NN denotes mouse
T6547 988-994 JJ denotes p 100H
T6546 984-987 DT denotes the
T6545 981-983 TO denotes to
T6544 973-980 JJ denotes similar
T6543 972-973 -LRB- denotes (
T6542 970-971 NNP denotes ]
T6541 968-970 CD denotes 32
T6540 967-968 NNP denotes [
T6539 960-966 NN denotes domain
T6538 956-959 NNP denotes HMG
T6537 952-955 PRP$ denotes its
T6536 946-951 VBZ denotes lacks
T6535 941-945 WDT denotes that
T6534 933-940 NN denotes protein
T6533 928-932 NNP denotes Sox6
T6532 918-927 VBN denotes truncated
T6531 916-917 DT denotes a
T6530 913-915 IN denotes of
T6529 898-912 NN denotes overexpression
T6528 896-897 , denotes ,
T6527 888-896 NN denotes contrast
T6526 885-887 IN denotes In
T6525 883-884 . denotes .
T6524 882-883 -RRB- denotes )
T6523 880-882 NN denotes 2B
T6522 873-879 NN denotes Figure
T6521 872-873 -LRB- denotes (
T6520 863-871 NN denotes activity
T6519 854-862 NN denotes reporter
T6518 848-853 JJ denotes E-Luc
T6517 845-847 IN denotes of
T6516 834-844 NN denotes repression
T6515 817-833 JJ denotes dosage-dependent
T6514 815-816 DT denotes a
T6513 812-814 TO denotes to
T6512 806-811 VBZ denotes leads
T6511 793-805 NN denotes transfection
T6510 783-792 JJ denotes transient
T6509 780-782 IN denotes by
T6508 774-779 NNS denotes cells
T6507 768-773 NNP denotes GM979
T6506 765-767 IN denotes in
T6505 760-764 NNP denotes Sox6
T6504 757-759 IN denotes of
T6503 742-756 NNP denotes Overexpression
T6502 740-741 . denotes .
T6501 739-740 -RRB- denotes )
T6500 732-739 NNPS denotes Methods
T6499 728-731 CC denotes and
T6498 718-727 NNPS denotes Materials
T6497 715-717 IN denotes in
T6496 706-714 VBN denotes detailed
T6495 705-706 -LRB- denotes (
T6494 702-704 CD denotes 2A
T6493 695-701 NN denotes Figure
T6492 692-694 IN denotes in
T6491 686-691 VBN denotes shown
T6490 683-685 IN denotes as
T6489 681-682 , denotes ,
T6488 677-681 NN denotes gene
T6487 668-676 NN denotes reporter
T6486 657-667 NN denotes luciferase
T6485 653-656 DT denotes the
T6484 650-652 IN denotes by
T6483 641-649 VBN denotes followed
T6482 639-640 , denotes ,
T6481 638-639 -RRB- denotes )
T6480 636-638 NN denotes kb
T6479 632-635 CD denotes 2.2
T6478 631-632 -LRB- denotes (
T6477 622-630 NN denotes promoter
T6476 613-621 JJ denotes proximal
T6475 610-612 JJ denotes ɛy
T6474 606-609 DT denotes the
T6473 603-605 TO denotes to
T6472 601-602 NNP denotes ]
T6471 599-601 CD denotes 31
T6470 598-599 NNP denotes [
T6469 596-597 -RRB- denotes )
T6468 594-596 NN denotes kb
T6467 590-593 CD denotes 2.5
T6466 589-590 -LRB- denotes (
T6465 581-588 NN denotes element
T6464 579-580 -RRB- denotes )
T6463 575-579 NNP denotes μLCR
T6462 574-575 -LRB- denotes (
T6461 564-573 NN denotes micro-LCR
T6460 562-563 DT denotes a
T6459 555-561 NN denotes fusing
T6458 552-554 IN denotes by
T6457 550-551 -RRB- denotes )
T6456 545-550 JJ denotes E-Luc
T6455 544-545 -LRB- denotes (
T6454 534-543 VBP denotes construct
T6453 525-533 NN denotes reporter
T6452 516-524 NN denotes promoter
T6451 513-515 JJ denotes ɛy
T6450 510-512 DT denotes an
T6449 500-509 VBD denotes generated
T6448 497-499 PRP denotes We
R4427 T6364 T6365 compound Studies,Using
R4428 T6365 T6365 ROOT Using,Using
R4429 T6366 T6368 compound GM979,Indicate
R4430 T6367 T6368 compound Cells,Indicate
R4431 T6368 T6365 dobj Indicate,Using
R4432 T6369 T6365 nsubj That,Using
R4433 T6370 T6372 nsubj Sox6,Represses
R4434 T6371 T6372 advmod Directly,Represses
R4435 T6372 T6369 nsubj Represses,That
R4436 T6373 T6374 det the,ɛy
R4437 T6374 T6376 compound ɛy,Promoter
R4438 T6375 T6376 compound Gene,Promoter
R4439 T6376 T6372 dobj Promoter,Represses
R4440 T6377 T6376 prep at,Promoter
R4441 T6378 T6383 det the,assays
R4442 T6379 T6380 compound Transcriptional,Level
R4443 T6380 T6383 nmod Level,assays
R4444 T6381 T6383 amod Real-time,assays
R4445 T6382 T6383 compound PCR,assays
R4446 T6383 T6377 pobj assays,at
R4447 T6384 T6383 punct (,assays
R4448 T6385 T6383 appos Figure,assays
R4449 T6386 T6385 nummod 1,Figure
R4450 T6387 T6385 punct ),Figure
R4451 T6388 T6397 nmod measure,activity
R4452 T6389 T6390 amod steady-state,levels
R4453 T6390 T6388 dobj levels,measure
R4454 T6391 T6390 prep of,levels
R4455 T6392 T6393 compound ɛy,mRNA
R4456 T6393 T6391 pobj mRNA,of
R4457 T6394 T6393 punct ",",mRNA
R4458 T6395 T6397 neg not,activity
R4459 T6396 T6397 amod transcriptional,activity
R4460 T6397 T6383 appos activity,assays
R4461 T6398 T6397 prep of,activity
R4462 T6399 T6401 det the,promoter
R4463 T6400 T6401 amod ɛy,promoter
R4464 T6401 T6398 pobj promoter,of
R4465 T6402 T6365 punct .,Using
R4466 T6403 T6404 aux To,investigate
R4467 T6404 T6420 advcl investigate,used
R4468 T6405 T6408 mark whether,acts
R4469 T6406 T6408 nsubj Sox6,acts
R4470 T6407 T6408 advmod directly,acts
R4471 T6408 T6404 ccomp acts,investigate
R4472 T6409 T6408 prep on,acts
R4473 T6410 T6413 det the,promoter
R4474 T6411 T6413 amod ɛy,promoter
R4475 T6412 T6413 compound gene,promoter
R4476 T6413 T6409 pobj promoter,on
R4477 T6414 T6413 prep at,promoter
R4478 T6415 T6417 det the,level
R4479 T6416 T6417 amod transcriptional,level
R4480 T6417 T6414 pobj level,at
R4481 T6418 T6420 punct ",",used
R4482 T6419 T6420 nsubj we,used
R4483 T6420 T6420 ROOT used,used
R4484 T6421 T6426 det an,assay
R4485 T6422 T6426 nmod in,assay
R4486 T6423 T6426 amod vitro,assay
R4487 T6424 T6426 nmod transient,assay
R4488 T6425 T6426 compound transfection,assay
R4489 T6426 T6420 dobj assay,used
R4490 T6427 T6426 cc and,assay
R4491 T6428 T6429 compound GM979,cells
R4492 T6429 T6426 conj cells,assay
R4493 T6430 T6420 punct ",",used
R4494 T6431 T6435 det a,line
R4495 T6432 T6435 amod murine,line
R4496 T6433 T6435 amod erythroleukemic,line
R4497 T6434 T6435 compound cell,line
R4498 T6435 T6420 dobj line,used
R4499 T6436 T6437 nsubj that,expresses
R4500 T6437 T6435 relcl expresses,line
R4501 T6438 T6439 det both,ɛy
R4502 T6439 T6437 dobj ɛy,expresses
R4503 T6440 T6439 cc and,ɛy
R4504 T6441 T6443 amod adult,globins
R4505 T6442 T6443 compound beta,globins
R4506 T6443 T6446 dep globins,]
R4507 T6444 T6446 nmod [,]
R4508 T6445 T6446 nummod 30,]
R4509 T6446 T6439 conj ],ɛy
R4510 T6447 T6420 punct .,used
R4511 T6448 T6449 nsubj We,generated
R4512 T6449 T6449 ROOT generated,generated
R4513 T6450 T6453 det an,reporter
R4514 T6451 T6453 amod ɛy,reporter
R4515 T6452 T6453 compound promoter,reporter
R4516 T6453 T6454 nsubj reporter,construct
R4517 T6454 T6449 ccomp construct,generated
R4518 T6455 T6456 punct (,E-Luc
R4519 T6456 T6454 dep E-Luc,construct
R4520 T6457 T6456 punct ),E-Luc
R4521 T6458 T6454 prep by,construct
R4522 T6459 T6458 pcomp fusing,by
R4523 T6460 T6461 det a,micro-LCR
R4524 T6461 T6459 dobj micro-LCR,fusing
R4525 T6462 T6463 punct (,μLCR
R4526 T6463 T6461 appos μLCR,micro-LCR
R4527 T6464 T6463 punct ),μLCR
R4528 T6465 T6461 conj element,micro-LCR
R4529 T6466 T6465 punct (,element
R4530 T6467 T6468 nummod 2.5,kb
R4531 T6468 T6465 appos kb,element
R4532 T6469 T6465 punct ),element
R4533 T6470 T6472 nmod [,]
R4534 T6471 T6472 nummod 31,]
R4535 T6472 T6461 appos ],micro-LCR
R4536 T6473 T6459 prep to,fusing
R4537 T6474 T6477 det the,promoter
R4538 T6475 T6477 amod ɛy,promoter
R4539 T6476 T6477 amod proximal,promoter
R4540 T6477 T6473 pobj promoter,to
R4541 T6478 T6477 punct (,promoter
R4542 T6479 T6480 nummod 2.2,kb
R4543 T6480 T6477 appos kb,promoter
R4544 T6481 T6477 punct ),promoter
R4545 T6482 T6459 punct ",",fusing
R4546 T6483 T6454 advcl followed,construct
R4547 T6484 T6483 agent by,followed
R4548 T6485 T6488 det the,gene
R4549 T6486 T6488 compound luciferase,gene
R4550 T6487 T6488 compound reporter,gene
R4551 T6488 T6484 pobj gene,by
R4552 T6489 T6483 punct ",",followed
R4553 T6490 T6491 mark as,shown
R4554 T6491 T6454 advcl shown,construct
R4555 T6492 T6491 prep in,shown
R4556 T6493 T6492 pobj Figure,in
R4557 T6494 T6493 nummod 2A,Figure
R4558 T6495 T6496 punct (,detailed
R4559 T6496 T6454 advcl detailed,construct
R4560 T6497 T6496 prep in,detailed
R4561 T6498 T6497 pobj Materials,in
R4562 T6499 T6498 cc and,Materials
R4563 T6500 T6498 conj Methods,Materials
R4564 T6501 T6496 punct ),detailed
R4565 T6502 T6449 punct .,generated
R4566 T6503 T6512 nsubj Overexpression,leads
R4567 T6504 T6503 prep of,Overexpression
R4568 T6505 T6504 pobj Sox6,of
R4569 T6506 T6503 prep in,Overexpression
R4570 T6507 T6508 compound GM979,cells
R4571 T6508 T6506 pobj cells,in
R4572 T6509 T6503 agent by,Overexpression
R4573 T6510 T6511 amod transient,transfection
R4574 T6511 T6509 pobj transfection,by
R4575 T6512 T6512 ROOT leads,leads
R4576 T6513 T6512 prep to,leads
R4577 T6514 T6516 det a,repression
R4578 T6515 T6516 amod dosage-dependent,repression
R4579 T6516 T6513 pobj repression,to
R4580 T6517 T6516 prep of,repression
R4581 T6518 T6520 amod E-Luc,activity
R4582 T6519 T6520 compound reporter,activity
R4583 T6520 T6517 pobj activity,of
R4584 T6521 T6523 punct (,2B
R4585 T6522 T6523 compound Figure,2B
R4586 T6523 T6520 appos 2B,activity
R4587 T6524 T6520 punct ),activity
R4588 T6525 T6512 punct .,leads
R4589 T6526 T6551 prep In,fails
R4590 T6527 T6526 pobj contrast,In
R4591 T6528 T6551 punct ",",fails
R4592 T6529 T6551 nsubj overexpression,fails
R4593 T6530 T6529 prep of,overexpression
R4594 T6531 T6534 det a,protein
R4595 T6532 T6534 amod truncated,protein
R4596 T6533 T6534 compound Sox6,protein
R4597 T6534 T6530 pobj protein,of
R4598 T6535 T6536 nsubj that,lacks
R4599 T6536 T6534 relcl lacks,protein
R4600 T6537 T6539 poss its,domain
R4601 T6538 T6539 compound HMG,domain
R4602 T6539 T6536 dobj domain,lacks
R4603 T6540 T6542 nmod [,]
R4604 T6541 T6542 nummod 32,]
R4605 T6542 T6539 appos ],domain
R4606 T6543 T6542 punct (,]
R4607 T6544 T6542 amod similar,]
R4608 T6545 T6544 prep to,similar
R4609 T6546 T6549 det the,allele
R4610 T6547 T6549 amod p 100H,allele
R4611 T6548 T6549 compound mouse,allele
R4612 T6549 T6545 pobj allele,to
R4613 T6550 T6542 punct ),]
R4614 T6551 T6551 ROOT fails,fails
R4615 T6552 T6553 aux to,repress
R4616 T6553 T6551 xcomp repress,fails
R4617 T6554 T6555 amod E-Luc,activity
R4618 T6555 T6553 dobj activity,repress
R4619 T6556 T6558 punct (,2B
R4620 T6557 T6558 compound Figure,2B
R4621 T6558 T6555 appos 2B,activity
R4622 T6559 T6558 punct ),2B
R4623 T6560 T6551 punct .,fails
R4624 T6561 T6562 det These,data
R4625 T6562 T6563 nsubj data,indicate
R4626 T6563 T6563 ROOT indicate,indicate
R4627 T6564 T6568 mark that,repress
R4628 T6565 T6566 amod Sox6,acts
R4629 T6566 T6568 nsubj acts,repress
R4630 T6567 T6568 aux to,repress
R4631 T6568 T6563 ccomp repress,indicate
R4632 T6569 T6571 det the,promoter
R4633 T6570 T6571 amod ɛy,promoter
R4634 T6571 T6568 dobj promoter,repress
R4635 T6572 T6571 prep at,promoter
R4636 T6573 T6575 det the,level
R4637 T6574 T6575 amod transcriptional,level
R4638 T6575 T6572 pobj level,at
R4639 T6576 T6563 punct .,indicate
R4640 T6577 T6580 nsubjpass Sox6,shown
R4641 T6578 T6580 aux has,shown
R4642 T6579 T6580 auxpass been,shown
R4643 T6580 T6580 ROOT shown,shown
R4644 T6581 T6582 aux to,act
R4645 T6582 T6580 xcomp act,shown
R4646 T6583 T6582 prep as,act
R4647 T6584 T6585 det a,repressor
R4648 T6585 T6583 pobj repressor,as
R4649 T6586 T6582 cc and,act
R4650 T6587 T6588 aux to,interact
R4651 T6588 T6582 conj interact,act
R4652 T6589 T6588 prep with,interact
R4653 T6590 T6593 det a,co-repressor
R4654 T6591 T6592 advmod widely,expressed
R4655 T6592 T6593 amod expressed,co-repressor
R4656 T6593 T6589 pobj co-repressor,with
R4657 T6594 T6593 punct ",",co-repressor
R4658 T6595 T6593 appos CtBP2,co-repressor
R4659 T6596 T6588 punct ",",interact
R4660 T6597 T6588 prep on,interact
R4661 T6598 T6600 det the,promoter
R4662 T6599 T6600 amod fgf-3,promoter
R4663 T6600 T6597 pobj promoter,on
R4664 T6601 T6603 nmod [,]
R4665 T6602 T6601 nummod 5,[
R4666 T6603 T6600 appos ],promoter
R4667 T6604 T6580 punct .,shown
R4668 T6605 T6607 nsubjpass CtBP2,expressed
R4669 T6606 T6607 auxpass is,expressed
R4670 T6607 T6607 ROOT expressed,expressed
R4671 T6608 T6607 prep in,expressed
R4672 T6609 T6610 compound GM979,cells
R4673 T6610 T6608 pobj cells,in
R4674 T6611 T6613 punct (,data
R4675 T6612 T6613 amod unpublished,data
R4676 T6613 T6610 appos data,cells
R4677 T6614 T6607 punct ),expressed
R4678 T6615 T6607 punct .,expressed
R4679 T6616 T6617 aux To,investigate
R4680 T6617 T6634 advcl investigate,introduced
R4681 T6618 T6624 mark whether,required
R4682 T6619 T6620 det the,interaction
R4683 T6620 T6624 nsubjpass interaction,required
R4684 T6621 T6620 prep with,interaction
R4685 T6622 T6621 pobj CtBP2,with
R4686 T6623 T6624 auxpass is,required
R4687 T6624 T6617 ccomp required,investigate
R4688 T6625 T6624 prep for,required
R4689 T6626 T6627 amod Sox6,repression
R4690 T6627 T6625 pobj repression,for
R4691 T6628 T6627 prep of,repression
R4692 T6629 T6631 det the,promoter
R4693 T6630 T6631 amod ɛy,promoter
R4694 T6631 T6628 pobj promoter,of
R4695 T6632 T6634 punct ",",introduced
R4696 T6633 T6634 nsubj we,introduced
R4697 T6634 T6634 ROOT introduced,introduced
R4698 T6635 T6637 det a,mutation
R4699 T6636 T6637 compound point,mutation
R4700 T6637 T6634 dobj mutation,introduced
R4701 T6638 T6637 punct (,mutation
R4702 T6639 T6637 appos L386H,mutation
R4703 T6640 T6637 punct ),mutation
R4704 T6641 T6634 prep in,introduced
R4705 T6642 T6644 det the,protein
R4706 T6643 T6644 amod Sox6,protein
R4707 T6644 T6641 pobj protein,in
R4708 T6645 T6649 nsubjpass that,reported
R4709 T6646 T6649 aux has,reported
R4710 T6647 T6649 auxpass been,reported
R4711 T6648 T6649 advmod previously,reported
R4712 T6649 T6644 relcl reported,protein
R4713 T6650 T6651 aux to,be
R4714 T6651 T6649 xcomp be,reported
R4715 T6652 T6651 acomp sufficient,be
R4716 T6653 T6654 aux to,abolish
R4717 T6654 T6652 xcomp abolish,sufficient
R4718 T6655 T6656 amod Sox6-CtBP2,interaction
R4719 T6656 T6654 dobj interaction,abolish
R4720 T6657 T6659 nmod [,]
R4721 T6658 T6657 nummod 5,[
R4722 T6659 T6644 appos ],protein
R4723 T6660 T6634 punct .,introduced
R4724 T6661 T6664 det This,change
R4725 T6662 T6664 amod amino,change
R4726 T6663 T6664 compound acid,change
R4727 T6664 T6665 nsubj change,is
R4728 T6665 T6665 ROOT is,is
R4729 T6666 T6665 neg not,is
R4730 T6667 T6665 prep in,is
R4731 T6668 T6672 det the,domain
R4732 T6669 T6670 compound HMG,DNA
R4733 T6670 T6672 compound DNA,domain
R4734 T6671 T6672 amod binding,domain
R4735 T6672 T6667 pobj domain,in
R4736 T6673 T6665 punct .,is
R4737 T6674 T6681 advmod However,retains
R4738 T6675 T6681 punct ",",retains
R4739 T6676 T6678 det this,version
R4740 T6677 T6678 amod mutant,version
R4741 T6678 T6681 nsubj version,retains
R4742 T6679 T6678 prep of,version
R4743 T6680 T6679 pobj Sox6,of
R4744 T6681 T6681 ROOT retains,retains
R4745 T6682 T6683 det the,ability
R4746 T6683 T6681 dobj ability,retains
R4747 T6684 T6685 aux to,repress
R4748 T6685 T6683 acl repress,ability
R4749 T6686 T6688 det the,promoter
R4750 T6687 T6688 amod ɛy,promoter
R4751 T6688 T6685 dobj promoter,repress
R4752 T6689 T6688 prep in,promoter
R4753 T6690 T6692 det the,assay
R4754 T6691 T6692 compound transfection,assay
R4755 T6692 T6689 pobj assay,in
R4756 T6693 T6695 punct (,2B
R4757 T6694 T6695 compound Figure,2B
R4758 T6695 T6692 appos 2B,assay
R4759 T6696 T6692 punct ),assay
R4760 T6697 T6681 punct ",",retains
R4761 T6698 T6681 advcl indicating,retains
R4762 T6699 T6701 mark that,represses
R4763 T6700 T6701 nsubj Sox6,represses
R4764 T6701 T6698 ccomp represses,indicating
R4765 T6702 T6704 det the,promoter
R4766 T6703 T6704 amod ɛy,promoter
R4767 T6704 T6701 dobj promoter,represses
R4768 T6705 T6704 prep in,promoter
R4769 T6706 T6708 det a,manner
R4770 T6707 T6708 amod CtBP2-independent,manner
R4771 T6708 T6705 pobj manner,in
R4772 T6709 T6681 punct .,retains
R4773 T6710 T6711 compound Deletion,analysis
R4774 T6711 T6723 nsubj analysis,defined
R4775 T6712 T6711 prep of,analysis
R4776 T6713 T6715 det the,promoter
R4777 T6714 T6715 amod ɛy,promoter
R4778 T6715 T6712 pobj promoter,of
R4779 T6716 T6711 punct ",",analysis
R4780 T6717 T6718 mark as,shown
R4781 T6718 T6711 advcl shown,analysis
R4782 T6719 T6718 prep in,shown
R4783 T6720 T6719 pobj Figure,in
R4784 T6721 T6720 nummod 2C,Figure
R4785 T6722 T6723 punct ",",defined
R4786 T6723 T6723 ROOT defined,defined
R4787 T6724 T6725 det a,region
R4788 T6725 T6723 dobj region,defined
R4789 T6726 T6727 punct (,−
R4790 T6727 T6728 amod −,63
R4791 T6728 T6723 npadvmod 63,defined
R4792 T6729 T6728 prep to,63
R4793 T6730 T6729 pobj −,to
R4794 T6731 T6730 appos 37,−
R4795 T6732 T6730 punct ),−
R4796 T6733 T6729 prep within,to
R4797 T6734 T6737 det the,promoter
R4798 T6735 T6737 amod ɛy,promoter
R4799 T6736 T6737 amod proximal,promoter
R4800 T6737 T6733 pobj promoter,within
R4801 T6738 T6739 nsubj that,is
R4802 T6739 T6737 relcl is,promoter
R4803 T6740 T6739 acomp critical,is
R4804 T6741 T6740 prep for,critical
R4805 T6742 T6743 amod Sox6,repression
R4806 T6743 T6741 pobj repression,for
R4807 T6744 T6723 punct .,defined
R4808 T6745 T6750 nsubj Analysis,reveals
R4809 T6746 T6745 prep of,Analysis
R4810 T6747 T6749 det this,region
R4811 T6748 T6749 amod short,region
R4812 T6749 T6746 pobj region,of
R4813 T6750 T6750 ROOT reveals,reveals
R4814 T6751 T6755 nummod two,sites
R4815 T6752 T6755 amod Sox/Sox6,sites
R4816 T6753 T6755 nmod consensus,sites
R4817 T6754 T6755 amod binding,sites
R4818 T6755 T6750 dobj sites,reveals
R4819 T6756 T6758 nmod [,]
R4820 T6757 T6758 nummod 5,]
R4821 T6758 T6761 compound ],3A
R4822 T6759 T6760 punct (,Figure
R4823 T6760 T6761 compound Figure,3A
R4824 T6761 T6750 oprd 3A,reveals
R4825 T6762 T6750 punct ),reveals
R4826 T6763 T6750 punct .,reveals
R4426 T6363 T6364 compound Transfection,Studies

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T5742 3055-3059 Protein denotes Sox6
T5741 2999-3002 Protein denotes HMG
T5740 2926-2933 Negative_regulation denotes abolish
T5739 2764-2772 Positive_regulation denotes required
T5738 2945-2956 Binding denotes interaction
T5737 2782-2792 Gene_expression denotes repression
T5736 2738-2749 Binding denotes interaction
T5735 2939-2944 Protein denotes CtBP2
T5734 2934-2938 Protein denotes Sox6
T5733 2859-2871 Protein denotes Sox6 protein
T5732 2777-2781 Protein denotes Sox6
T5731 2755-2760 Protein denotes CtBP2
T5730 2666-2675 Gene_expression denotes expressed
T5729 2657-2662 Protein denotes CtBP2
T5728 2599-2608 Gene_expression denotes expressed
T5727 2576-2584 Binding denotes interact
T5726 2576-2584 Binding denotes interact
T5725 2637-2655 Protein denotes fgf-3 promoter [5]
T5724 2623-2628 Protein denotes CtBP2
T5723 2527-2531 Protein denotes Sox6
T5722 1079-1083 Protein denotes Sox6
T5721 960-966 Entity denotes domain
T5720 898-912 Positive_regulation denotes overexpression
T5719 898-912 Gene_expression denotes overexpression
T5718 1028-1031 Protein denotes Luc
T5717 988-1007 Protein denotes p 100H mouse allele
T5716 956-959 Protein denotes HMG
T5715 928-932 Protein denotes Sox6
T5714 834-844 Negative_regulation denotes repression
T5713 742-756 Positive_regulation denotes Overexpression
T5712 742-756 Gene_expression denotes Overexpression
T5711 848-862 Protein denotes E-Luc reporter
T5710 760-764 Protein denotes Sox6
T5709 657-681 Protein denotes luciferase reporter gene
T5708 547-550 Protein denotes Luc
T5707 450-459 Gene_expression denotes expresses
T5706 305-313 Entity denotes promoter
T5705 478-490 Protein denotes beta globins
T5704 271-275 Protein denotes Sox6
T5703 190-197 Protein denotes ɛy mRNA
T5702 89-97 Entity denotes Promoter
T5701 53-57 Protein denotes Sox6
T5749 3431-3435 Protein denotes Sox6
T5748 3427-3430 Protein denotes Sox
T5747 3373-3383 Gene_expression denotes repression
T5746 3368-3372 Protein denotes Sox6
T5745 3184-3192 Entity denotes promoter
T5744 3198-3203 Protein denotes CtBP2
T5743 3162-3166 Protein denotes Sox6
R3938 T5701 T5702 partOf Sox6,Promoter
R3939 T5705 T5707 themeOf beta globins,expresses
R3940 T5710 T5712 themeOf Sox6,Overexpression
R3941 T5711 T5714 themeOf E-Luc reporter,repression
R3942 T5712 T5713 themeOf Overexpression,Overexpression
R3943 T5713 T5714 causeOf Overexpression,repression
R3944 T5715 T5719 themeOf Sox6,overexpression
R3945 T5716 T5721 partOf HMG,domain
R3946 T5719 T5720 themeOf overexpression,overexpression
R3947 T5723 T5726 themeOf Sox6,interact
R3948 T5723 T5727 themeOf Sox6,interact
R3949 T5724 T5726 themeOf CtBP2,interact
R3950 T5724 T5728 themeOf CtBP2,expressed
R3951 T5725 T5727 themeOf fgf-3 promoter [5],interact
R3952 T5729 T5730 themeOf CtBP2,expressed
R3953 T5731 T5736 themeOf CtBP2,interaction
R3954 T5732 T5737 themeOf Sox6,repression
R3955 T5734 T5738 themeOf Sox6,interaction
R3956 T5735 T5738 themeOf CtBP2,interaction
R3957 T5736 T5739 causeOf interaction,required
R3958 T5737 T5739 themeOf repression,required
R3959 T5738 T5740 themeOf interaction,abolish
R3960 T5746 T5747 themeOf Sox6,repression

testone

Id Subject Object Predicate Lexical cue
T5517 3224-3232 Negative_regulation denotes Deletion
T5516 3167-3176 Negative_regulation denotes represses
T5515 2945-2956 Binding denotes interaction
T5514 2926-2933 Negative_regulation denotes abolish
T5513 2782-2792 Negative_regulation denotes repression
T5512 2738-2749 Binding denotes interaction
T5511 2666-2675 Gene_expression denotes expressed
T5510 2576-2584 Binding denotes interact
T5509 1107-1115 Entity denotes promoter
T5508 1092-1099 Negative_regulation denotes repress
T5507 203-218 Transcription denotes transcriptional
T5506 67-76 Negative_regulation denotes Represses
T5505 3368-3372 Protein denotes Sox6
T5504 3326-3328 Protein denotes ɛy
T5503 3249-3251 Protein denotes ɛy
T5502 3198-3203 Protein denotes CtBP2
T5501 3181-3183 Protein denotes ɛy
T5500 3162-3166 Protein denotes Sox6
T5499 3095-3097 Protein denotes ɛy
T5498 3055-3059 Protein denotes Sox6
T5497 2939-2944 Protein denotes CtBP2
T5496 2934-2938 Protein denotes Sox6
T5495 2859-2863 Protein denotes Sox6
T5494 2800-2802 Protein denotes ɛy
T5493 2777-2781 Protein denotes Sox6
T5492 2755-2760 Protein denotes CtBP2
T5491 2657-2662 Protein denotes CtBP2
T5490 2637-2642 Protein denotes fgf-3
T5489 2623-2628 Protein denotes CtBP2
T5488 2527-2531 Protein denotes Sox6
T5487 1104-1106 Protein denotes ɛy
T5486 1079-1083 Protein denotes Sox6
T5485 928-932 Protein denotes Sox6
T5484 760-764 Protein denotes Sox6
T5483 657-667 Protein denotes luciferase
T5482 610-612 Protein denotes ɛy
T5481 513-515 Protein denotes ɛy
T5480 478-490 Protein denotes beta globins
T5479 465-467 Protein denotes ɛy
T5478 297-299 Protein denotes ɛy
T5477 271-275 Protein denotes Sox6
T5476 235-237 Protein denotes ɛy
T5475 190-192 Protein denotes ɛy
T5474 81-83 Protein denotes ɛy
T5473 53-57 Protein denotes Sox6
R3885 T5473 T5506 causeOf Sox6,Represses
R3886 T5486 T5508 causeOf Sox6,repress
R3887 T5488 T5510 themeOf Sox6,interact
R3888 T5489 T5510 themeOf CtBP2,interact
R3889 T5491 T5511 themeOf CtBP2,expressed
R3890 T5492 T5512 themeOf CtBP2,interaction
R3891 T5496 T5515 themeOf Sox6,interaction
R3892 T5497 T5515 themeOf CtBP2,interaction
R3893 T5500 T5516 causeOf Sox6,represses
R3894 T5509 T5487 partOf promoter,ɛy
R3895 T5509 T5508 themeOf promoter,repress
R3896 T5515 T5514 themeOf interaction,abolish

test3

Id Subject Object Predicate Lexical cue
T5591 3368-3372 Protein denotes Sox6
T5590 3326-3328 Protein denotes ɛy
T5589 3249-3251 Protein denotes ɛy
T5588 3198-3203 Protein denotes CtBP2
T5587 3181-3183 Protein denotes ɛy
T5586 3162-3166 Protein denotes Sox6
T5585 3095-3097 Protein denotes ɛy
T5584 3055-3059 Protein denotes Sox6
T5583 2945-2956 Binding denotes interaction
T5582 2939-2944 Protein denotes CtBP2
T5581 2934-2938 Protein denotes Sox6
T5580 2859-2863 Protein denotes Sox6
T5579 2800-2802 Protein denotes ɛy
T5578 2782-2792 Negative_regulation denotes repression
T5577 2777-2781 Protein denotes Sox6
T5576 2764-2772 Positive_regulation denotes required
T5575 2755-2760 Protein denotes CtBP2
T5574 2738-2749 Binding denotes interaction
T5573 2666-2675 Gene_expression denotes expressed
T5572 2657-2662 Protein denotes CtBP2
T5571 2637-2642 Protein denotes fgf-3
T5570 2623-2628 Protein denotes CtBP2
T5569 2599-2608 Gene_expression denotes expressed
T5568 2527-2531 Protein denotes Sox6
T5567 1104-1106 Protein denotes ɛy
T5566 1092-1099 Negative_regulation denotes repress
T5565 1079-1083 Protein denotes Sox6
T5564 928-932 Protein denotes Sox6
T5563 760-764 Protein denotes Sox6
T5562 657-667 Protein denotes luciferase
T5561 610-612 Protein denotes ɛy
T5560 513-515 Protein denotes ɛy
T5559 478-490 Protein denotes beta globins
T5558 465-467 Protein denotes ɛy
T5557 297-299 Protein denotes ɛy
T5556 271-275 Protein denotes Sox6
T5555 235-237 Protein denotes ɛy
T5554 190-192 Protein denotes ɛy
T5553 81-83 Protein denotes ɛy
T5552 67-76 Negative_regulation denotes Represses
T5551 53-57 Protein denotes Sox6
T5550 3368-3372 Protein denotes Sox6
T5549 3326-3328 Protein denotes ɛy
T5548 3249-3251 Protein denotes ɛy
T5547 3198-3203 Protein denotes CtBP2
T5546 3181-3183 Protein denotes ɛy
T5545 3162-3166 Protein denotes Sox6
T5544 3095-3097 Protein denotes ɛy
T5543 3055-3059 Protein denotes Sox6
T5542 2939-2944 Protein denotes CtBP2
T5541 2934-2938 Protein denotes Sox6
T5540 2859-2863 Protein denotes Sox6
T5539 2800-2802 Protein denotes ɛy
T5538 2777-2781 Protein denotes Sox6
T5537 2755-2760 Protein denotes CtBP2
T5536 2657-2662 Protein denotes CtBP2
T5535 2637-2642 Protein denotes fgf-3
T5534 2623-2628 Protein denotes CtBP2
T5533 2527-2531 Protein denotes Sox6
T5532 1104-1106 Protein denotes ɛy
T5531 1079-1083 Protein denotes Sox6
T5530 928-932 Protein denotes Sox6
T5529 760-764 Protein denotes Sox6
T5528 657-667 Protein denotes luciferase
T5527 610-612 Protein denotes ɛy
T5526 513-515 Protein denotes ɛy
T5525 478-490 Protein denotes beta globins
T5524 465-467 Protein denotes ɛy
T5523 297-299 Protein denotes ɛy
T5522 271-275 Protein denotes Sox6
T5521 235-237 Protein denotes ɛy
T5520 190-192 Protein denotes ɛy
T5519 81-83 Protein denotes ɛy
T5518 53-57 Protein denotes Sox6
R3897 T5551 T5552 causeOf Sox6,Represses
R3898 T5553 T5551 themeOf ɛy,Sox6
R3899 T5557 T5556 themeOf ɛy,Sox6
R3900 T5558 T5556 themeOf ɛy,Sox6
R3901 T5559 T5556 themeOf beta globins,Sox6
R3902 T5565 T5566 causeOf Sox6,repress
R3903 T5568 T5569 themeOf Sox6,expressed
R3904 T5570 T5568 themeOf CtBP2,Sox6
R3905 T5570 T5569 themeOf CtBP2,expressed
R3906 T5572 T5573 themeOf CtBP2,expressed
R3907 T5574 T5576 causeOf interaction,required
R3908 T5575 T5574 themeOf CtBP2,interaction
R3909 T5578 T5576 themeOf repression,required
R3910 T5578 T5577 themeOf repression,Sox6
R3911 T5579 T5577 themeOf ɛy,Sox6
R3912 T5581 T5583 themeOf Sox6,interaction
R3913 T5582 T5583 themeOf CtBP2,interaction
R3914 T5587 T5586 themeOf ɛy,Sox6
R3915 T5588 T5586 themeOf CtBP2,Sox6
R3916 T5591 T5590 themeOf Sox6,ɛy