Id |
Subject |
Object |
Predicate |
Lexical cue |
T2433 |
0-4 |
RB |
denotes |
Here |
T2434 |
8-14 |
VBP |
denotes |
report |
T2435 |
5-7 |
PRP |
denotes |
we |
T2436 |
15-18 |
DT |
denotes |
the |
T2437 |
19-30 |
NN |
denotes |
application |
T2438 |
31-33 |
IN |
denotes |
of |
T2439 |
34-38 |
DT |
denotes |
this |
T2440 |
50-58 |
NN |
denotes |
approach |
T2441 |
39-49 |
VBN |
denotes |
integrated |
T2442 |
59-61 |
TO |
denotes |
to |
T2443 |
62-67 |
VB |
denotes |
study |
T2444 |
68-71 |
DT |
denotes |
the |
T2445 |
72-84 |
NN |
denotes |
significance |
T2446 |
85-87 |
IN |
denotes |
of |
T2447 |
88-91 |
NN |
denotes |
sex |
T2448 |
92-94 |
IN |
denotes |
on |
T2449 |
95-98 |
DT |
denotes |
the |
T2450 |
107-119 |
NNS |
denotes |
determinants |
T2451 |
99-106 |
JJ |
denotes |
genetic |
T2452 |
120-122 |
IN |
denotes |
of |
T2453 |
123-130 |
NN |
denotes |
obesity |
T2454 |
131-134 |
CC |
denotes |
and |
T2455 |
135-138 |
DT |
denotes |
the |
T2456 |
150-160 |
NN |
denotes |
regulation |
T2457 |
139-149 |
VBN |
denotes |
associated |
T2458 |
161-163 |
IN |
denotes |
of |
T2459 |
164-169 |
NN |
denotes |
liver |
T2460 |
175-185 |
NN |
denotes |
expression |
T2461 |
170-174 |
NN |
denotes |
gene |
T2462 |
186-188 |
IN |
denotes |
in |
T2463 |
189-191 |
DT |
denotes |
an |
T2464 |
195-205 |
NN |
denotes |
intercross |
T2465 |
192-194 |
NN |
denotes |
F2 |
T2466 |
206-213 |
VBN |
denotes |
derived |
T2467 |
214-218 |
IN |
denotes |
from |
T2468 |
219-222 |
DT |
denotes |
the |
T2469 |
230-237 |
NNS |
denotes |
strains |
T2470 |
223-229 |
JJ |
denotes |
inbred |
T2471 |
238-243 |
NN |
denotes |
C57BL |
T2472 |
244-246 |
NN |
denotes |
6J |
T2473 |
243-244 |
HYPH |
denotes |
/ |
T2474 |
247-248 |
-LRB- |
denotes |
( |
T2475 |
248-250 |
NN |
denotes |
B6 |
T2476 |
250-251 |
-RRB- |
denotes |
) |
T2477 |
252-255 |
CC |
denotes |
and |
T2478 |
256-259 |
NN |
denotes |
C3H |
T2479 |
260-263 |
NN |
denotes |
HeJ |
T2480 |
259-260 |
HYPH |
denotes |
/ |
T2481 |
264-265 |
-LRB- |
denotes |
( |
T2482 |
265-268 |
NN |
denotes |
C3H |
T2483 |
268-269 |
-RRB- |
denotes |
) |
T2484 |
270-272 |
IN |
denotes |
on |
T2485 |
273-275 |
DT |
denotes |
an |
T2486 |
308-318 |
NN |
denotes |
background |
T2487 |
276-290 |
NN |
denotes |
apolipoprotein |
T2488 |
291-292 |
NN |
denotes |
E |
T2489 |
293-297 |
JJ |
denotes |
null |
T2490 |
298-299 |
-LRB- |
denotes |
( |
T2491 |
299-303 |
NN |
denotes |
ApoE |
T2492 |
303-304 |
SYM |
denotes |
− |
T2493 |
304-305 |
HYPH |
denotes |
/ |
T2494 |
305-306 |
SYM |
denotes |
− |
T2495 |
306-307 |
-RRB- |
denotes |
) |
T2496 |
318-319 |
. |
denotes |
. |
T2497 |
319-451 |
sentence |
denotes |
The BXH.ApoE−/− population was designed to recapitulate several of the phenotypes associated with the so-called metabolic syndrome. |
T2498 |
320-323 |
DT |
denotes |
The |
T2499 |
336-346 |
NN |
denotes |
population |
T2500 |
324-332 |
NN |
denotes |
BXH.ApoE |
T2501 |
332-333 |
SYM |
denotes |
− |
T2502 |
333-334 |
HYPH |
denotes |
/ |
T2503 |
334-335 |
SYM |
denotes |
− |
T2504 |
351-359 |
VBN |
denotes |
designed |
T2505 |
347-350 |
VBD |
denotes |
was |
T2506 |
360-362 |
TO |
denotes |
to |
T2507 |
363-375 |
VB |
denotes |
recapitulate |
T2508 |
376-383 |
JJ |
denotes |
several |
T2509 |
384-386 |
IN |
denotes |
of |
T2510 |
387-390 |
DT |
denotes |
the |
T2511 |
391-401 |
NNS |
denotes |
phenotypes |
T2512 |
402-412 |
VBN |
denotes |
associated |
T2513 |
413-417 |
IN |
denotes |
with |
T2514 |
418-421 |
DT |
denotes |
the |
T2515 |
442-450 |
NN |
denotes |
syndrome |
T2516 |
422-424 |
RB |
denotes |
so |
T2517 |
425-431 |
VBN |
denotes |
called |
T2518 |
424-425 |
HYPH |
denotes |
- |
T2519 |
432-441 |
JJ |
denotes |
metabolic |
T2520 |
450-451 |
. |
denotes |
. |
T2521 |
451-568 |
sentence |
denotes |
The cross consists of 334 animals of both sexes, allowing us to specifically test for the dependence of QTLs on sex. |
T2522 |
452-455 |
DT |
denotes |
The |
T2523 |
456-461 |
NN |
denotes |
cross |
T2524 |
462-470 |
VBZ |
denotes |
consists |
T2525 |
471-473 |
IN |
denotes |
of |
T2526 |
474-477 |
CD |
denotes |
334 |
T2527 |
478-485 |
NNS |
denotes |
animals |
T2528 |
486-488 |
IN |
denotes |
of |
T2529 |
489-493 |
DT |
denotes |
both |
T2530 |
494-499 |
NNS |
denotes |
sexes |
T2531 |
499-501 |
, |
denotes |
, |
T2532 |
501-509 |
VBG |
denotes |
allowing |
T2533 |
510-512 |
PRP |
denotes |
us |
T2534 |
529-533 |
VB |
denotes |
test |
T2535 |
513-515 |
TO |
denotes |
to |
T2536 |
516-528 |
RB |
denotes |
specifically |
T2537 |
534-537 |
IN |
denotes |
for |
T2538 |
538-541 |
DT |
denotes |
the |
T2539 |
542-552 |
NN |
denotes |
dependence |
T2540 |
553-555 |
IN |
denotes |
of |
T2541 |
556-560 |
NNS |
denotes |
QTLs |
T2542 |
561-563 |
IN |
denotes |
on |
T2543 |
564-567 |
NN |
denotes |
sex |
T2544 |
567-568 |
. |
denotes |
. |
T2545 |
568-678 |
sentence |
denotes |
We detected several thousand gene expression QTLs (eQTLs), a significant proportion of which were sex-biased. |
T2546 |
569-571 |
PRP |
denotes |
We |
T2547 |
572-580 |
VBD |
denotes |
detected |
T2548 |
581-588 |
JJ |
denotes |
several |
T2549 |
589-597 |
CD |
denotes |
thousand |
T2550 |
614-618 |
NNS |
denotes |
QTLs |
T2551 |
598-602 |
NN |
denotes |
gene |
T2552 |
603-613 |
NN |
denotes |
expression |
T2553 |
619-620 |
-LRB- |
denotes |
( |
T2554 |
620-625 |
NNS |
denotes |
eQTLs |
T2555 |
625-626 |
-RRB- |
denotes |
) |
T2556 |
626-628 |
, |
denotes |
, |
T2557 |
628-629 |
DT |
denotes |
a |
T2558 |
642-652 |
NN |
denotes |
proportion |
T2559 |
630-641 |
JJ |
denotes |
significant |
T2560 |
662-666 |
VBD |
denotes |
were |
T2561 |
653-655 |
IN |
denotes |
of |
T2562 |
656-661 |
WDT |
denotes |
which |
T2563 |
667-670 |
NN |
denotes |
sex |
T2564 |
671-677 |
VBN |
denotes |
biased |
T2565 |
670-671 |
HYPH |
denotes |
- |
T2566 |
677-678 |
. |
denotes |
. |
T2567 |
678-814 |
sentence |
denotes |
We used these analyses to dissect the genetic regulation of the gonadal fat mass trait and to identify genes associated with the trait. |
T2568 |
679-681 |
PRP |
denotes |
We |
T2569 |
682-686 |
VBD |
denotes |
used |
T2570 |
687-692 |
DT |
denotes |
these |
T2571 |
693-701 |
NNS |
denotes |
analyses |
T2572 |
702-704 |
TO |
denotes |
to |
T2573 |
705-712 |
VB |
denotes |
dissect |
T2574 |
713-716 |
DT |
denotes |
the |
T2575 |
725-735 |
NN |
denotes |
regulation |
T2576 |
717-724 |
JJ |
denotes |
genetic |
T2577 |
736-738 |
IN |
denotes |
of |
T2578 |
739-742 |
DT |
denotes |
the |
T2579 |
760-765 |
NN |
denotes |
trait |
T2580 |
743-750 |
JJ |
denotes |
gonadal |
T2581 |
755-759 |
NN |
denotes |
mass |
T2582 |
751-754 |
NN |
denotes |
fat |
T2583 |
766-769 |
CC |
denotes |
and |
T2584 |
770-772 |
TO |
denotes |
to |
T2585 |
773-781 |
VB |
denotes |
identify |
T2586 |
782-787 |
NNS |
denotes |
genes |
T2587 |
788-798 |
VBN |
denotes |
associated |
T2588 |
799-803 |
IN |
denotes |
with |
T2589 |
804-807 |
DT |
denotes |
the |
T2590 |
808-813 |
NN |
denotes |
trait |
T2591 |
813-814 |
. |
denotes |
. |
R642 |
T2443 |
T2437 |
acl |
study,application |
R644 |
T2444 |
T2445 |
det |
the,significance |
R646 |
T2445 |
T2443 |
dobj |
significance,study |
R647 |
T2446 |
T2445 |
prep |
of,significance |
R649 |
T2447 |
T2446 |
pobj |
sex,of |
R650 |
T2448 |
T2445 |
prep |
on,significance |
R652 |
T2449 |
T2450 |
det |
the,determinants |
R653 |
T2450 |
T2448 |
pobj |
determinants,on |
R654 |
T2451 |
T2450 |
amod |
genetic,determinants |
R656 |
T2452 |
T2450 |
prep |
of,determinants |
R657 |
T2453 |
T2452 |
pobj |
obesity,of |
R658 |
T2454 |
T2450 |
cc |
and,determinants |
R660 |
T2455 |
T2456 |
det |
the,regulation |
R661 |
T2456 |
T2450 |
conj |
regulation,determinants |
R662 |
T2457 |
T2456 |
amod |
associated,regulation |
R664 |
T2458 |
T2456 |
prep |
of,regulation |
R665 |
T2459 |
T2460 |
compound |
liver,expression |
R666 |
T2460 |
T2458 |
pobj |
expression,of |
R667 |
T2461 |
T2460 |
compound |
gene,expression |
R668 |
T2462 |
T2443 |
prep |
in,study |
R670 |
T2463 |
T2464 |
det |
an,intercross |
R671 |
T2464 |
T2462 |
pobj |
intercross,in |
R672 |
T2465 |
T2464 |
compound |
F2,intercross |
R674 |
T2466 |
T2464 |
acl |
derived,intercross |
R675 |
T2467 |
T2466 |
prep |
from,derived |
R676 |
T2468 |
T2469 |
det |
the,strains |
R678 |
T2469 |
T2467 |
pobj |
strains,from |
R679 |
T2470 |
T2469 |
amod |
inbred,strains |
R680 |
T2471 |
T2472 |
compound |
C57BL,6J |
R681 |
T2472 |
T2469 |
appos |
6J,strains |
R684 |
T2473 |
T2472 |
punct |
/,6J |
R685 |
T2474 |
T2475 |
punct |
(,B6 |
R687 |
T2475 |
T2472 |
parataxis |
B6,6J |
R688 |
T2476 |
T2475 |
punct |
),B6 |
R689 |
T2477 |
T2472 |
cc |
and,6J |
R691 |
T2478 |
T2479 |
compound |
C3H,HeJ |
R692 |
T2479 |
T2472 |
conj |
HeJ,6J |
R693 |
T2480 |
T2479 |
punct |
/,HeJ |
R695 |
T2481 |
T2482 |
punct |
(,C3H |
R696 |
T2482 |
T2479 |
parataxis |
C3H,HeJ |
R697 |
T2483 |
T2482 |
punct |
),C3H |
R699 |
T2484 |
T2469 |
prep |
on,strains |
R700 |
T2485 |
T2486 |
det |
an,background |
R702 |
T2486 |
T2484 |
pobj |
background,on |
R703 |
T2487 |
T2488 |
compound |
apolipoprotein,E |
R704 |
T2488 |
T2489 |
npadvmod |
E,null |
R706 |
T2489 |
T2486 |
amod |
null,background |
R707 |
T2490 |
T2491 |
punct |
(,ApoE |
R708 |
T2491 |
T2486 |
parataxis |
ApoE,background |
R710 |
T2492 |
T2491 |
punct |
−,ApoE |
R711 |
T2493 |
T2491 |
punct |
/,ApoE |
R712 |
T2494 |
T2491 |
punct |
−,ApoE |
R713 |
T2433 |
T2434 |
advmod |
Here,report |
R714 |
T2495 |
T2491 |
punct |
),ApoE |
R715 |
T2496 |
T2434 |
punct |
.,report |
R716 |
T2498 |
T2499 |
det |
The,population |
R717 |
T2435 |
T2434 |
nsubj |
we,report |
R718 |
T2499 |
T2504 |
nsubjpass |
population,designed |
R719 |
T2500 |
T2499 |
nmod |
BXH.ApoE,population |
R720 |
T2501 |
T2500 |
punct |
−,BXH.ApoE |
R721 |
T2502 |
T2500 |
punct |
/,BXH.ApoE |
R722 |
T2503 |
T2500 |
punct |
−,BXH.ApoE |
R723 |
T2505 |
T2504 |
auxpass |
was,designed |
R724 |
T2506 |
T2507 |
aux |
to,recapitulate |
R725 |
T2436 |
T2437 |
det |
the,application |
R726 |
T2507 |
T2504 |
advcl |
recapitulate,designed |
R727 |
T2508 |
T2507 |
dobj |
several,recapitulate |
R728 |
T2509 |
T2508 |
prep |
of,several |
R729 |
T2437 |
T2434 |
dobj |
application,report |
R730 |
T2510 |
T2511 |
det |
the,phenotypes |
R731 |
T2511 |
T2509 |
pobj |
phenotypes,of |
R732 |
T2512 |
T2511 |
acl |
associated,phenotypes |
R733 |
T2438 |
T2437 |
prep |
of,application |
R734 |
T2513 |
T2512 |
prep |
with,associated |
R735 |
T2439 |
T2440 |
det |
this,approach |
R736 |
T2514 |
T2515 |
det |
the,syndrome |
R737 |
T2515 |
T2513 |
pobj |
syndrome,with |
R738 |
T2516 |
T2517 |
advmod |
so,called |
R739 |
T2517 |
T2515 |
amod |
called,syndrome |
R740 |
T2440 |
T2438 |
pobj |
approach,of |
R741 |
T2518 |
T2517 |
punct |
-,called |
R742 |
T2519 |
T2515 |
amod |
metabolic,syndrome |
R743 |
T2520 |
T2504 |
punct |
.,designed |
R744 |
T2441 |
T2440 |
amod |
integrated,approach |
R745 |
T2522 |
T2523 |
det |
The,cross |
R746 |
T2523 |
T2524 |
nsubj |
cross,consists |
R747 |
T2442 |
T2443 |
aux |
to,study |
R748 |
T2525 |
T2524 |
prep |
of,consists |
R749 |
T2549 |
T2550 |
nummod |
thousand,QTLs |
R750 |
T2526 |
T2527 |
nummod |
334,animals |
R751 |
T2527 |
T2525 |
pobj |
animals,of |
R752 |
T2528 |
T2527 |
prep |
of,animals |
R753 |
T2529 |
T2530 |
det |
both,sexes |
R754 |
T2530 |
T2528 |
pobj |
sexes,of |
R755 |
T2531 |
T2524 |
punct |
", ",consists |
R756 |
T2550 |
T2547 |
dobj |
QTLs,detected |
R757 |
T2532 |
T2524 |
advcl |
allowing,consists |
R758 |
T2533 |
T2534 |
nsubj |
us,test |
R759 |
T2534 |
T2532 |
ccomp |
test,allowing |
R760 |
T2551 |
T2550 |
compound |
gene,QTLs |
R761 |
T2535 |
T2534 |
aux |
to,test |
R762 |
T2536 |
T2534 |
advmod |
specifically,test |
R763 |
T2537 |
T2534 |
prep |
for,test |
R764 |
T2552 |
T2550 |
compound |
expression,QTLs |
R765 |
T2538 |
T2539 |
det |
the,dependence |
R766 |
T2539 |
T2537 |
pobj |
dependence,for |
R767 |
T2540 |
T2539 |
prep |
of,dependence |
R768 |
T2553 |
T2550 |
punct |
(,QTLs |
R769 |
T2541 |
T2540 |
pobj |
QTLs,of |
R770 |
T2542 |
T2539 |
prep |
on,dependence |
R771 |
T2543 |
T2542 |
pobj |
sex,on |
R772 |
T2544 |
T2524 |
punct |
.,consists |
R773 |
T2546 |
T2547 |
nsubj |
We,detected |
R774 |
T2554 |
T2550 |
appos |
eQTLs,QTLs |
R775 |
T2548 |
T2549 |
amod |
several,thousand |
R776 |
T2555 |
T2550 |
punct |
),QTLs |
R777 |
T2556 |
T2550 |
punct |
", ",QTLs |
R778 |
T2557 |
T2558 |
det |
a,proportion |
R779 |
T2558 |
T2560 |
dep |
proportion,were |
R780 |
T2559 |
T2558 |
amod |
significant,proportion |
R781 |
T2560 |
T2550 |
relcl |
were,QTLs |
R782 |
T2561 |
T2558 |
prep |
of,proportion |
R783 |
T2562 |
T2561 |
pobj |
which,of |
R784 |
T2563 |
T2564 |
npadvmod |
sex,biased |
R785 |
T2564 |
T2560 |
acomp |
biased,were |
R786 |
T2565 |
T2564 |
punct |
-,biased |
R787 |
T2566 |
T2547 |
punct |
.,detected |
R788 |
T2568 |
T2569 |
nsubj |
We,used |
R789 |
T2570 |
T2571 |
det |
these,analyses |
R790 |
T2571 |
T2569 |
dobj |
analyses,used |
R791 |
T2572 |
T2573 |
aux |
to,dissect |
R792 |
T2573 |
T2569 |
advcl |
dissect,used |
R793 |
T2574 |
T2575 |
det |
the,regulation |
R794 |
T2575 |
T2573 |
dobj |
regulation,dissect |
R795 |
T2576 |
T2575 |
amod |
genetic,regulation |
R796 |
T2577 |
T2575 |
prep |
of,regulation |
R797 |
T2578 |
T2579 |
det |
the,trait |
R798 |
T2579 |
T2577 |
pobj |
trait,of |
R799 |
T2580 |
T2581 |
amod |
gonadal,mass |
R800 |
T2581 |
T2579 |
compound |
mass,trait |
R801 |
T2582 |
T2581 |
compound |
fat,mass |
R802 |
T2583 |
T2573 |
cc |
and,dissect |
R803 |
T2584 |
T2585 |
aux |
to,identify |
R804 |
T2585 |
T2573 |
conj |
identify,dissect |
R805 |
T2586 |
T2585 |
dobj |
genes,identify |
R806 |
T2587 |
T2586 |
acl |
associated,genes |
R807 |
T2588 |
T2587 |
prep |
with,associated |
R808 |
T2589 |
T2590 |
det |
the,trait |
R809 |
T2590 |
T2588 |
pobj |
trait,with |
R810 |
T2591 |
T2569 |
punct |
.,used |