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PMC:1315279 / 37027-37938 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T8531 0-3 DT denotes The
T8532 4-11 NN denotes pathway
T8533 58-68 VBN denotes identified
T8534 12-14 IN denotes by
T8535 28-37 VBZ denotes regulates
T8536 15-20 WDT denotes which
T8537 21-27 NN denotes leptin
T8538 38-42 NN denotes bone
T8539 43-53 NN denotes resorption
T8540 54-57 VBD denotes was
T8541 69-71 TO denotes to
T8542 72-79 VB denotes involve
T8543 80-83 DT denotes the
T8544 104-110 NN denotes system
T8545 84-95 JJ denotes sympathetic
T8546 96-103 JJ denotes nervous
T8547 111-119 VBG denotes relaying
T8548 120-122 IN denotes to
T8549 123-126 DT denotes the
T8550 127-138 NNS denotes osteoblasts
T8551 139-142 IN denotes via
T8552 143-146 DT denotes the
T8553 160-167 NN denotes pathway
T8554 147-148 NN denotes β
T8555 149-159 JJ denotes adrenergic
T8556 148-149 HYPH denotes -
T8557 168-175 VBG denotes leading
T8558 176-178 IN denotes to
T8559 179-182 DT denotes the
T8560 183-190 NN denotes release
T8561 191-193 IN denotes of
T8562 194-200 NN denotes growth
T8563 201-208 NNS denotes factors
T8564 209-218 VBG denotes including
T8565 219-224 NN denotes RANKL
T8566 225-229 WDT denotes that
T8567 230-236 VBZ denotes causes
T8568 237-240 DT denotes the
T8569 241-252 NNS denotes osteoclasts
T8570 256-262 VB denotes thrive
T8571 253-255 TO denotes to
T8572 263-264 -LRB- denotes [
T8573 264-265 CD denotes 8
T8574 265-266 , denotes ,
T8575 266-268 CD denotes 18
T8576 268-269 SYM denotes –
T8577 269-271 CD denotes 20
T8578 271-272 -RRB- denotes ]
T8579 272-273 . denotes .
T8580 273-417 sentence denotes The lowering of leptin levels in aged Sam68−/− mice is consistent with these mice having a high bone mass compared with their aged littermates.
T8581 274-277 DT denotes The
T8582 278-286 NN denotes lowering
T8583 326-328 VBZ denotes is
T8584 287-289 IN denotes of
T8585 290-296 NN denotes leptin
T8586 297-303 NNS denotes levels
T8587 304-306 IN denotes in
T8588 307-311 JJ denotes aged
T8589 321-325 NNS denotes mice
T8590 312-317 NN denotes Sam68
T8591 317-318 SYM denotes −
T8592 318-319 HYPH denotes /
T8593 319-320 SYM denotes −
T8594 329-339 JJ denotes consistent
T8595 340-344 IN denotes with
T8596 345-350 DT denotes these
T8597 351-355 NNS denotes mice
T8598 356-362 VBG denotes having
T8599 363-364 DT denotes a
T8600 375-379 NN denotes mass
T8601 365-369 JJ denotes high
T8602 370-374 NN denotes bone
T8603 380-388 VBN denotes compared
T8604 389-393 IN denotes with
T8605 394-399 PRP$ denotes their
T8606 405-416 NNS denotes littermates
T8607 400-404 JJ denotes aged
T8608 416-417 . denotes .
T8609 417-607 sentence denotes These data would suggest that the leptin-sympathetic pathway is unaltered in Sam68−/− mice and that the lowering of leptin may explain the lower levels of CTX in the serum of Sam68−/− mice.
T8610 418-423 DT denotes These
T8611 424-428 NNS denotes data
T8612 435-442 VB denotes suggest
T8613 429-434 MD denotes would
T8614 443-447 IN denotes that
T8615 479-481 VBZ denotes is
T8616 448-451 DT denotes the
T8617 471-478 NN denotes pathway
T8618 452-458 NN denotes leptin
T8619 459-470 JJ denotes sympathetic
T8620 458-459 HYPH denotes -
T8621 482-491 JJ denotes unaltered
T8622 492-494 IN denotes in
T8623 495-500 NN denotes Sam68
T8624 504-508 NNS denotes mice
T8625 500-501 SYM denotes −
T8626 501-502 HYPH denotes /
T8627 502-503 SYM denotes −
T8628 509-512 CC denotes and
T8629 513-517 IN denotes that
T8630 545-552 VB denotes explain
T8631 518-521 DT denotes the
T8632 522-530 NN denotes lowering
T8633 531-533 IN denotes of
T8634 534-540 NN denotes leptin
T8635 541-544 MD denotes may
T8636 553-556 DT denotes the
T8637 563-569 NNS denotes levels
T8638 557-562 JJR denotes lower
T8639 570-572 IN denotes of
T8640 573-576 NN denotes CTX
T8641 577-579 IN denotes in
T8642 580-583 DT denotes the
T8643 584-589 NN denotes serum
T8644 590-592 IN denotes of
T8645 593-598 NN denotes Sam68
T8646 602-606 NNS denotes mice
T8647 598-599 SYM denotes −
T8648 599-600 HYPH denotes /
T8649 600-601 SYM denotes −
T8650 606-607 . denotes .
T8651 607-911 sentence denotes These findings suggest that Sam68 may be regulating bone metabolism at two different levels: (1) the absence of Sam68 results in lower leptin levels that may reduce bone resorption via the sympathetic nervous system and (2) the absence of Sam68 favors osteoblast, rather than adipocyte, differentiation.
T8652 608-613 DT denotes These
T8653 614-622 NNS denotes findings
T8654 623-630 VBP denotes suggest
T8655 726-733 VBZ denotes results
T8656 631-635 IN denotes that
T8657 649-659 VBG denotes regulating
T8658 636-641 NN denotes Sam68
T8659 642-645 MD denotes may
T8660 646-648 VB denotes be
T8661 660-664 NN denotes bone
T8662 665-675 NN denotes metabolism
T8663 676-678 IN denotes at
T8664 679-682 CD denotes two
T8665 693-699 NNS denotes levels
T8666 683-692 JJ denotes different
T8667 699-701 : denotes :
T8668 701-702 -LRB- denotes (
T8669 702-703 LS denotes 1
T8670 703-704 -RRB- denotes )
T8671 705-708 DT denotes the
T8672 709-716 NN denotes absence
T8673 717-719 IN denotes of
T8674 720-725 NN denotes Sam68
T8675 734-736 IN denotes in
T8676 737-742 JJR denotes lower
T8677 750-756 NNS denotes levels
T8678 743-749 NN denotes leptin
T8679 757-761 WDT denotes that
T8680 766-772 VB denotes reduce
T8681 762-765 MD denotes may
T8682 773-777 NN denotes bone
T8683 778-788 NN denotes resorption
T8684 789-792 IN denotes via
T8685 793-796 DT denotes the
T8686 817-823 NN denotes system
T8687 797-808 JJ denotes sympathetic
T8688 809-816 JJ denotes nervous
T8689 824-827 CC denotes and
T8690 828-829 -LRB- denotes (
T8691 829-830 LS denotes 2
T8692 853-859 VBZ denotes favors
T8693 830-831 -RRB- denotes )
T8694 832-835 DT denotes the
T8695 836-843 NN denotes absence
T8696 844-846 IN denotes of
T8697 847-852 NN denotes Sam68
T8698 860-870 NN denotes osteoblast
T8699 895-910 NN denotes differentiation
T8700 870-872 , denotes ,
T8701 872-878 RB denotes rather
T8702 879-883 IN denotes than
T8703 884-893 NN denotes adipocyte
T8704 893-895 , denotes ,
T8705 910-911 . denotes .
R5219 T8619 T8617 amod sympathetic,pathway
R5221 T8620 T8619 punct -,sympathetic
R5222 T8621 T8615 acomp unaltered,is
R5223 T8622 T8615 prep in,is
R5225 T8623 T8624 nmod Sam68,mice
R5227 T8624 T8622 pobj mice,in
R5229 T8625 T8623 punct −,Sam68
R5230 T8626 T8623 punct /,Sam68
R5232 T8627 T8623 punct −,Sam68
R5233 T8531 T8532 det The,pathway
R5234 T8628 T8615 cc and,is
R5235 T8629 T8630 mark that,explain
R5236 T8630 T8615 conj explain,is
R5237 T8631 T8632 det the,lowering
R5238 T8632 T8630 nsubj lowering,explain
R5239 T8633 T8632 prep of,lowering
R5240 T8634 T8633 pobj leptin,of
R5241 T8532 T8533 nsubjpass pathway,identified
R5242 T8635 T8630 aux may,explain
R5243 T8636 T8637 det the,levels
R5244 T8637 T8630 dobj levels,explain
R5245 T8534 T8535 prep by,regulates
R5246 T8638 T8637 amod lower,levels
R5247 T8639 T8637 prep of,levels
R5248 T8640 T8639 pobj CTX,of
R5249 T8535 T8532 relcl regulates,pathway
R5250 T8641 T8637 prep in,levels
R5251 T8642 T8643 det the,serum
R5252 T8643 T8641 pobj serum,in
R5253 T8536 T8534 pobj which,by
R5254 T8644 T8643 prep of,serum
R5255 T8645 T8646 nmod Sam68,mice
R5256 T8646 T8644 pobj mice,of
R5257 T8537 T8535 nsubj leptin,regulates
R5258 T8647 T8645 punct −,Sam68
R5259 T8648 T8645 punct /,Sam68
R5260 T8649 T8645 punct −,Sam68
R5261 T8538 T8539 compound bone,resorption
R5262 T8650 T8612 punct .,suggest
R5263 T8652 T8653 det These,findings
R5264 T8539 T8535 dobj resorption,regulates
R5265 T8653 T8654 nsubj findings,suggest
R5266 T8654 T8655 ccomp suggest,results
R5267 T8540 T8533 auxpass was,identified
R5268 T8656 T8657 mark that,regulating
R5269 T8657 T8654 ccomp regulating,suggest
R5270 T8541 T8542 aux to,involve
R5271 T8658 T8657 nsubj Sam68,regulating
R5272 T8659 T8657 aux may,regulating
R5273 T8542 T8533 xcomp involve,identified
R5274 T8660 T8657 aux be,regulating
R5275 T8661 T8662 compound bone,metabolism
R5276 T8662 T8657 dobj metabolism,regulating
R5277 T8543 T8544 det the,system
R5278 T8663 T8657 prep at,regulating
R5279 T8664 T8665 nummod two,levels
R5280 T8665 T8663 pobj levels,at
R5281 T8544 T8542 dobj system,involve
R5282 T8666 T8665 amod different,levels
R5283 T8667 T8655 punct : ,results
R5284 T8668 T8669 punct (,1
R5285 T8545 T8544 amod sympathetic,system
R5286 T8669 T8655 meta 1,results
R5287 T8670 T8669 punct ),1
R5288 T8671 T8672 det the,absence
R5289 T8672 T8655 nsubj absence,results
R5290 T8673 T8672 prep of,absence
R5291 T8674 T8673 pobj Sam68,of
R5292 T8546 T8544 amod nervous,system
R5293 T8675 T8655 prep in,results
R5294 T8676 T8677 amod lower,levels
R5295 T8677 T8675 pobj levels,in
R5296 T8547 T8544 acl relaying,system
R5297 T8678 T8677 compound leptin,levels
R5298 T8679 T8680 dep that,reduce
R5299 T8680 T8677 relcl reduce,levels
R5300 T8548 T8547 prep to,relaying
R5301 T8681 T8680 aux may,reduce
R5302 T8682 T8683 compound bone,resorption
R5303 T8683 T8680 dobj resorption,reduce
R5304 T8549 T8550 det the,osteoblasts
R5305 T8684 T8680 prep via,reduce
R5306 T8685 T8686 det the,system
R5307 T8686 T8684 pobj system,via
R5308 T8550 T8548 pobj osteoblasts,to
R5309 T8687 T8686 amod sympathetic,system
R5310 T8688 T8686 amod nervous,system
R5311 T8689 T8655 cc and,results
R5312 T8551 T8547 prep via,relaying
R5313 T8690 T8691 punct (,2
R5314 T8691 T8692 meta 2,favors
R5315 T8692 T8655 conj favors,results
R5316 T8552 T8553 det the,pathway
R5317 T8693 T8691 punct ),2
R5318 T8694 T8695 det the,absence
R5319 T8695 T8692 nsubj absence,favors
R5320 T8553 T8551 pobj pathway,via
R5321 T8696 T8695 prep of,absence
R5322 T8697 T8696 pobj Sam68,of
R5323 T8698 T8699 nmod osteoblast,differentiation
R5324 T8554 T8555 npadvmod β,adrenergic
R5325 T8699 T8692 dobj differentiation,favors
R5326 T8700 T8698 punct ", ",osteoblast
R5327 T8701 T8702 advmod rather,than
R5328 T8555 T8553 amod adrenergic,pathway
R5329 T8702 T8698 cc than,osteoblast
R5330 T8703 T8698 conj adipocyte,osteoblast
R5331 T8556 T8555 punct -,adrenergic
R5332 T8704 T8699 punct ", ",differentiation
R5333 T8705 T8655 punct .,results
R5334 T8557 T8547 advcl leading,relaying
R5336 T8558 T8557 prep to,leading
R5340 T8559 T8560 det the,release
R5341 T8560 T8558 pobj release,to
R5345 T8561 T8560 prep of,release
R5348 T8562 T8563 compound growth,factors
R5351 T8563 T8561 pobj factors,of
R5352 T8564 T8563 prep including,factors
R5354 T8565 T8564 pobj RANKL,including
R5356 T8566 T8567 dep that,causes
R5359 T8567 T8563 relcl causes,factors
R5362 T8568 T8569 det the,osteoclasts
R5363 T8569 T8570 nsubj osteoclasts,thrive
R5365 T8570 T8567 ccomp thrive,causes
R5368 T8571 T8570 aux to,thrive
R5371 T8572 T8573 punct [,8
R5374 T8573 T8533 parataxis 8,identified
R5377 T8574 T8573 punct ",",8
R5381 T8575 T8573 appos 18,8
R5384 T8576 T8577 punct –,20
R5388 T8577 T8575 prep 20,18
R5395 T8578 T8573 punct ],8
R5398 T8579 T8533 punct .,identified
R5401 T8581 T8582 det The,lowering
R5405 T8582 T8583 nsubj lowering,is
R5409 T8584 T8582 prep of,lowering
R5414 T8585 T8586 compound leptin,levels
R5418 T8586 T8584 pobj levels,of
R5422 T8587 T8582 prep in,lowering
R5426 T8588 T8589 amod aged,mice
R5430 T8589 T8587 pobj mice,in
R5434 T8590 T8589 nmod Sam68,mice
R5437 T8591 T8590 punct −,Sam68
R5440 T8592 T8590 punct /,Sam68
R5447 T8593 T8590 punct −,Sam68
R5450 T8594 T8583 acomp consistent,is
R5452 T8595 T8594 prep with,consistent
R5453 T8596 T8597 det these,mice
R5454 T8597 T8598 nsubj mice,having
R5455 T8598 T8595 pcomp having,with
R5456 T8599 T8600 det a,mass
R5457 T8600 T8598 dobj mass,having
R5458 T8601 T8600 amod high,mass
R5459 T8602 T8600 compound bone,mass
R5460 T8603 T8598 prep compared,having
R5461 T8604 T8603 prep with,compared
R5462 T8605 T8606 poss their,littermates
R5463 T8606 T8604 pobj littermates,with
R5464 T8607 T8606 amod aged,littermates
R5465 T8608 T8583 punct .,is
R5466 T8610 T8611 det These,data
R5467 T8611 T8612 nsubj data,suggest
R5468 T8613 T8612 aux would,suggest
R5469 T8614 T8615 mark that,is
R5470 T8615 T8612 advcl is,suggest
R5471 T8616 T8617 det the,pathway
R5472 T8617 T8615 nsubj pathway,is
R5473 T8618 T8619 npadvmod leptin,sympathetic

2_test

Id Subject Object Predicate Lexical cue
16362077-10660043-85614475 264-265 10660043 denotes 8
16362077-12419242-85614476 266-268 12419242 denotes 18
16362077-15724149-85614476 266-268 15724149 denotes 18
16362077-16143109-85614476 266-268 16143109 denotes 18
T47250 264-265 10660043 denotes 8
T62595 266-268 12419242 denotes 18
T28381 266-268 15724149 denotes 18
T91353 266-268 16143109 denotes 18

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T6876 28-37 GO:0065007 denotes regulates
T6877 38-53 GO:0045453 denotes bone resorption
T6878 84-110 UBERON:0000013 denotes sympathetic nervous system
T6879 127-138 CL:0000062 denotes osteoblasts
T6880 219-224 PR:000002107 denotes RANKL
T6881 241-252 CL:0000092 denotes osteoclasts
T6882 312-317 PR:000009279 denotes Sam68
T6883 321-325 NCBITaxon:10088 denotes mice
T6884 351-355 NCBITaxon:10088 denotes mice
T6885 495-500 PR:000009279 denotes Sam68
T6886 504-508 NCBITaxon:10088 denotes mice
T6887 584-589 UBERON:0001977 denotes serum
T6888 593-598 PR:000009279 denotes Sam68
T6889 602-606 NCBITaxon:10088 denotes mice
T6890 636-641 PR:000009279 denotes Sam68
T6891 649-659 GO:0065007 denotes regulating
T6892 665-675 GO:0008152 denotes metabolism
T6893 720-725 PR:000009279 denotes Sam68
T6894 773-788 GO:0045453 denotes bone resorption
T6895 797-823 UBERON:0000013 denotes sympathetic nervous system
T6896 847-852 PR:000009279 denotes Sam68
T6897 860-870 CL:0000062 denotes osteoblast
T6898 884-893 CL:0000136 denotes adipocyte

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T7272 219-224 PR_EXT:000002107 denotes RANKL
T7273 241-252 CL:0000092 denotes osteoclasts
T7274 290-296 CHEBI_PR_EXT:leptin denotes leptin
T7275 307-311 GO_PATO_EXT:aging_or_agedness denotes aged
T7276 312-317 PR_EXT:000009279 denotes Sam68
T7277 317-318 SO_EXT:sequence_nullness_or_absence denotes −
T7278 319-320 SO_EXT:sequence_nullness_or_absence denotes −
T7279 321-325 NCBITaxon:10088 denotes mice
T7280 351-355 NCBITaxon:10088 denotes mice
T7281 370-374 UBERON_EXT:bone_element_or_tissue denotes bone
T7282 400-404 GO_PATO_EXT:aging_or_agedness denotes aged
T7283 452-458 CHEBI_PR_EXT:leptin denotes leptin
T7284 495-500 PR_EXT:000009279 denotes Sam68
T7285 500-501 SO_EXT:sequence_nullness_or_absence denotes −
T7286 502-503 SO_EXT:sequence_nullness_or_absence denotes −
T7287 504-508 NCBITaxon:10088 denotes mice
T7288 534-540 CHEBI_PR_EXT:leptin denotes leptin
T7289 584-589 UBERON:0001977 denotes serum
T7290 593-598 PR_EXT:000009279 denotes Sam68
T7291 598-599 SO_EXT:sequence_nullness_or_absence denotes −
T7292 600-601 SO_EXT:sequence_nullness_or_absence denotes −
T7293 602-606 NCBITaxon:10088 denotes mice
T7294 636-641 PR_EXT:000009279 denotes Sam68
T7295 649-659 GO:0065007 denotes regulating
T7296 660-664 UBERON_EXT:bone_element_or_tissue denotes bone
T7297 665-675 GO:0008152 denotes metabolism
T7298 720-725 PR_EXT:000009279 denotes Sam68
T7299 743-749 CHEBI_PR_EXT:leptin denotes leptin
T7300 773-777 UBERON_EXT:bone_element_or_tissue denotes bone
T7301 773-788 GO:0045453 denotes bone resorption
T7302 797-823 UBERON:0000013 denotes sympathetic nervous system
T7303 847-852 PR_EXT:000009279 denotes Sam68
T7304 860-870 CL:0000062 denotes osteoblast
T7305 884-893 CL:0000136 denotes adipocyte
T7306 895-910 GO_RO_EXT:developmental_differentiation_process denotes differentiation
T7262 21-27 CHEBI_PR_EXT:leptin denotes leptin
T7263 28-37 GO:0065007 denotes regulates
T7264 38-42 UBERON_EXT:bone_element_or_tissue denotes bone
T7265 38-53 GO:0045453 denotes bone resorption
T7266 84-110 UBERON:0000013 denotes sympathetic nervous system
T7267 127-138 CL:0000062 denotes osteoblasts
T7268 147-159 GO_PR_EXT:beta_adrenergic_receptor denotes β-adrenergic
T7269 183-190 GO_EXT:biological_release denotes release
T7270 194-200 GO_EXT:biological_growth_entity_or_process denotes growth
T7271 194-208 GO_EXT:0008083 denotes growth factors