PMC:1310901 / 625-857 JSONTXT

{"project":"bionlp-st-ge-2016-reference-eval","denotations":[{"id":"T876","span":{"begin":44,"end":49},"obj":"Protein"},{"id":"T877","span":{"begin":106,"end":116},"obj":"Regulation"},{"id":"T878","span":{"begin":120,"end":125},"obj":"Protein"},{"id":"T879","span":{"begin":126,"end":136},"obj":"Gene_expression"}],"relations":[{"id":"R634","pred":"themeOf","subj":"T878","obj":"T879"},{"id":"R635","pred":"themeOf","subj":"T879","obj":"T877"}],"text":"ctively. Therefore, we investigated whether IRF-4 promoter methylation or mutation may be involved in the regulation of IRF-4 expression in leukemia cells. Whereas promoter mutations or structural rearrangements could be excluded as"}

{"project":"events-check-again","denotations":[{"id":"T812","span":{"begin":44,"end":49},"obj":"Protein"},{"id":"T813","span":{"begin":106,"end":116},"obj":"Regulation"},{"id":"T814","span":{"begin":120,"end":125},"obj":"Protein"},{"id":"T815","span":{"begin":126,"end":136},"obj":"Gene_expression"}],"relations":[{"id":"R601","pred":"themeOf","subj":"T814","obj":"T815"},{"id":"R602","pred":"themeOf","subj":"T815","obj":"T813"}],"attributes":[{"id":"M20","pred":"Speculation","subj":"T813","obj":"true"}],"text":"ctively. Therefore, we investigated whether IRF-4 promoter methylation or mutation may be involved in the regulation of IRF-4 expression in leukemia cells. Whereas promoter mutations or structural rearrangements could be excluded as"}

{"project":"GO-CC","denotations":[{"id":"T699","span":{"begin":149,"end":154},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"ctively. Therefore, we investigated whether IRF-4 promoter methylation or mutation may be involved in the regulation of IRF-4 expression in leukemia cells. Whereas promoter mutations or structural rearrangements could be excluded as"}

{"project":"sentences","denotations":[{"id":"T108","span":{"begin":9,"end":155},"obj":"Sentence"},{"id":"T5","span":{"begin":9,"end":155},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"ctively. Therefore, we investigated whether IRF-4 promoter methylation or mutation may be involved in the regulation of IRF-4 expression in leukemia cells. Whereas promoter mutations or structural rearrangements could be excluded as"}

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{"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T519","span":{"begin":7,"end":8},"obj":"."},{"id":"T520","span":{"begin":9,"end":18},"obj":"RB"},{"id":"T521","span":{"begin":18,"end":19},"obj":","},{"id":"T522","span":{"begin":20,"end":22},"obj":"PRP"},{"id":"T523","span":{"begin":23,"end":35},"obj":"VBD"},{"id":"T524","span":{"begin":36,"end":43},"obj":"IN"},{"id":"T525","span":{"begin":44,"end":49},"obj":"NN"},{"id":"T526","span":{"begin":50,"end":58},"obj":"NN"},{"id":"T527","span":{"begin":59,"end":70},"obj":"NN"},{"id":"T528","span":{"begin":71,"end":73},"obj":"CC"},{"id":"T529","span":{"begin":74,"end":82},"obj":"NN"},{"id":"T530","span":{"begin":83,"end":86},"obj":"MD"},{"id":"T531","span":{"begin":87,"end":89},"obj":"VB"},{"id":"T532","span":{"begin":90,"end":98},"obj":"VBN"},{"id":"T533","span":{"begin":99,"end":101},"obj":"IN"},{"id":"T534","span":{"begin":102,"end":105},"obj":"DT"},{"id":"T535","span":{"begin":106,"end":116},"obj":"NN"},{"id":"T536","span":{"begin":117,"end":119},"obj":"IN"},{"id":"T537","span":{"begin":120,"end":125},"obj":"NN"},{"id":"T538","span":{"begin":126,"end":136},"obj":"NN"},{"id":"T539","span":{"begin":137,"end":139},"obj":"IN"},{"id":"T540","span":{"begin":140,"end":148},"obj":"NN"},{"id":"T541","span":{"begin":149,"end":154},"obj":"NNS"},{"id":"T542","span":{"begin":154,"end":155},"obj":"."},{"id":"T543","span":{"begin":156,"end":163},"obj":"IN"},{"id":"T544","span":{"begin":164,"end":172},"obj":"NN"},{"id":"T545","span":{"begin":173,"end":182},"obj":"NNS"},{"id":"T546","span":{"begin":183,"end":185},"obj":"CC"},{"id":"T547","span":{"begin":186,"end":196},"obj":"JJ"},{"id":"T548","span":{"begin":197,"end":211},"obj":"NNS"},{"id":"T549","span":{"begin":212,"end":217},"obj":"MD"},{"id":"T550","span":{"begin":218,"end":220},"obj":"VB"},{"id":"T551","span":{"begin":221,"end":229},"obj":"VBN"},{"id":"T552","span":{"begin":230,"end":232},"obj":"IN"}],"relations":[{"id":"R410","pred":"punct","subj":"T521","obj":"T523"},{"id":"R411","pred":"nsubj","subj":"T522","obj":"T523"},{"id":"R412","pred":"ROOT","subj":"T523","obj":"T523"},{"id":"R413","pred":"mark","subj":"T524","obj":"T532"},{"id":"R414","pred":"compound","subj":"T525","obj":"T527"},{"id":"R415","pred":"compound","subj":"T526","obj":"T527"},{"id":"R416","pred":"nsubjpass","subj":"T527","obj":"T532"},{"id":"R417","pred":"cc","subj":"T528","obj":"T527"},{"id":"R418","pred":"conj","subj":"T529","obj":"T527"},{"id":"R419","pred":"aux","subj":"T530","obj":"T532"},{"id":"R420","pred":"auxpass","subj":"T531","obj":"T532"},{"id":"R421","pred":"ccomp","subj":"T532","obj":"T523"},{"id":"R422","pred":"prep","subj":"T533","obj":"T532"},{"id":"R423","pred":"det","subj":"T534","obj":"T535"},{"id":"R424","pred":"pobj","subj":"T535","obj":"T533"},{"id":"R425","pred":"prep","subj":"T536","obj":"T535"},{"id":"R426","pred":"compound","subj":"T537","obj":"T538"},{"id":"R427","pred":"pobj","subj":"T538","obj":"T536"},{"id":"R428","pred":"prep","subj":"T539","obj":"T535"},{"id":"R429","pred":"compound","subj":"T540","obj":"T541"},{"id":"R430","pred":"pobj","subj":"T541","obj":"T539"},{"id":"R431","pred":"punct","subj":"T542","obj":"T523"},{"id":"R432","pred":"mark","subj":"T543","obj":"T551"},{"id":"R433","pred":"compound","subj":"T544","obj":"T545"},{"id":"R434","pred":"nsubjpass","subj":"T545","obj":"T551"},{"id":"R435","pred":"cc","subj":"T546","obj":"T545"},{"id":"R436","pred":"amod","subj":"T547","obj":"T548"},{"id":"R437","pred":"conj","subj":"T548","obj":"T545"},{"id":"R438","pred":"aux","subj":"T549","obj":"T551"},{"id":"R439","pred":"auxpass","subj":"T550","obj":"T551"},{"id":"R441","pred":"prep","subj":"T552","obj":"T551"},{"id":"R409","pred":"advmod","subj":"T520","obj":"T523"}],"text":"ctively. Therefore, we investigated whether IRF-4 promoter methylation or mutation may be involved in the regulation of IRF-4 expression in leukemia cells. Whereas promoter mutations or structural rearrangements could be excluded as"}

{"project":"GO-BP","denotations":[{"id":"T115","span":{"begin":106,"end":116},"obj":"http://purl.obolibrary.org/obo/GO_0065007"},{"id":"T123","span":{"begin":59,"end":70},"obj":"http://purl.obolibrary.org/obo/GO_0032259"}],"text":"ctively. Therefore, we investigated whether IRF-4 promoter methylation or mutation may be involved in the regulation of IRF-4 expression in leukemia cells. Whereas promoter mutations or structural rearrangements could be excluded as"}

{"project":"bionlp-st-ge-2016-reference-tees","denotations":[{"id":"T847","span":{"begin":44,"end":58},"obj":"Protein"},{"id":"T848","span":{"begin":120,"end":125},"obj":"Protein"},{"id":"T849","span":{"begin":126,"end":136},"obj":"Gene_expression"},{"id":"T850","span":{"begin":106,"end":116},"obj":"Regulation"}],"relations":[{"id":"R619","pred":"themeOf","subj":"T848","obj":"T849"},{"id":"R620","pred":"themeOf","subj":"T849","obj":"T850"}],"text":"ctively. Therefore, we investigated whether IRF-4 promoter methylation or mutation may be involved in the regulation of IRF-4 expression in leukemia cells. Whereas promoter mutations or structural rearrangements could be excluded as"}

{"project":"bionlp-st-ge-2016-reference","denotations":[{"id":"T79","span":{"begin":44,"end":49},"obj":"Protein"},{"id":"T80","span":{"begin":106,"end":116},"obj":"Regulation"},{"id":"T81","span":{"begin":120,"end":125},"obj":"Protein"},{"id":"T82","span":{"begin":126,"end":136},"obj":"Gene_expression"}],"relations":[{"id":"R652","pred":"themeOf","subj":"T81","obj":"T82"},{"id":"R653","pred":"themeOf","subj":"T82","obj":"T80"}],"attributes":[{"id":"M25","pred":"Speculation","subj":"T80","obj":"true"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"ctively. Therefore, we investigated whether IRF-4 promoter methylation or mutation may be involved in the regulation of IRF-4 expression in leukemia cells. Whereas promoter mutations or structural rearrangements could be excluded as"}

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T401","span":{"begin":44,"end":49},"obj":"Q15306"},{"id":"T402","span":{"begin":120,"end":125},"obj":"Q15306"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"ctively. Therefore, we investigated whether IRF-4 promoter methylation or mutation may be involved in the regulation of IRF-4 expression in leukemia cells. Whereas promoter mutations or structural rearrangements could be excluded as"}

{"project":"test2","denotations":[{"id":"T43","span":{"begin":44,"end":49},"obj":"Protein"},{"id":"T44","span":{"begin":106,"end":116},"obj":"Regulation"},{"id":"T45","span":{"begin":120,"end":125},"obj":"Protein"},{"id":"T46","span":{"begin":126,"end":136},"obj":"Gene_expression"}],"relations":[{"id":"R23","pred":"themeOf","subj":"T45","obj":"T46"},{"id":"R24","pred":"themeOf","subj":"T46","obj":"T44"}],"attributes":[{"id":"M8","pred":"Negation","subj":"T44","obj":"true"}],"text":"ctively. Therefore, we investigated whether IRF-4 promoter methylation or mutation may be involved in the regulation of IRF-4 expression in leukemia cells. Whereas promoter mutations or structural rearrangements could be excluded as"}