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PMC:1310901 / 15972-17534 JSONTXT

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bionlp-st-ge-2016-reference-eval

Id Subject Object Predicate Lexical cue
T8464 185-195 Gene_expression denotes expression
T8465 862-870 Gene_expression denotes negative
T8466 1052-1060 Gene_expression denotes positive
T8467 1179-1187 Gene_expression denotes positive
T8468 1391-1404 Transcription denotes transcription
T8469 1547-1555 Gene_expression denotes negative
T8470 63-68 Protein denotes IRF-4
T8471 174-179 Protein denotes IRF-4
T8472 567-572 Protein denotes IRF-4
T8473 856-861 Protein denotes IRF-4
T8474 1046-1051 Protein denotes IRF-4
T8475 1173-1178 Protein denotes IRF-4
T8476 1385-1390 Protein denotes IRF-4
T8477 1541-1546 Protein denotes IRF-4
R7043 T8471 T8464 themeOf IRF-4,expression
R7044 T8473 T8465 themeOf IRF-4,negative
R7045 T8476 T8468 themeOf IRF-4,transcription

events-check-again

Id Subject Object Predicate Lexical cue Negation
T8433 63-68 Protein denotes IRF-4
T8434 174-179 Protein denotes IRF-4
T8435 185-195 Gene_expression denotes expression
T8436 567-572 Protein denotes IRF-4
T8437 856-861 Protein denotes IRF-4
T8438 862-870 Gene_expression denotes negative true
T8439 1046-1051 Protein denotes IRF-4
T8440 1052-1060 Gene_expression denotes positive
T8441 1173-1178 Protein denotes IRF-4
T8442 1179-1187 Gene_expression denotes positive
T8443 1385-1390 Protein denotes IRF-4
T8444 1391-1404 Transcription denotes transcription
T8445 1541-1546 Protein denotes IRF-4
T8446 1547-1555 Gene_expression denotes negative true
R7032 T8434 T8435 themeOf IRF-4,expression
R7033 T8437 T8438 themeOf IRF-4,negative
R7034 T8439 T8440 themeOf IRF-4,positive
R7035 T8441 T8442 themeOf IRF-4,positive
R7036 T8443 T8444 themeOf IRF-4,transcription
R7037 T8445 T8446 themeOf IRF-4,negative

GO-CC

Id Subject Object Predicate Lexical cue
T8387 1195-1200 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T8388 1424-1429 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T8389 1556-1561 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T8390 1424-1443 http://purl.obolibrary.org/obo/GO_0009986 denotes cells is associated
T8383 95-100 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T8384 367-372 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T8385 909-914 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T8386 1066-1071 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

sentences

Id Subject Object Predicate Lexical cue
T7831 0-100 Sentence denotes Methylation-sensitive enzymes do not cut specific sites in the IRF-4 promoter in hematopoietic cells
T7832 101-340 Sentence denotes To further investigate promoter methylation as a regulatory mechanism of IRF-4 gene expression, restriction-PCR-assays were performed (20,24), where only methylated DNA would not be cut enabling subsequent PCR amplification and vice versa.
T7833 341-518 Sentence denotes Genomic DNA from leukemic cells Jurkat, CML-T1, U-937, K-562, EM-2 and BV-173 was digested with the methylation-sensitive enzymes HpaII, Bsh1236I and HaeII-isochizomer Bsp143II.
T7834 519-644 Sentence denotes EcoRI, which has no recognition site within the IRF-4 promoter, and the methylation-resistant enzyme MspI served as controls.
T7835 645-746 Sentence denotes Two separate amplification reactions were performed, generating two fragments, F1 and F2 (Figure 3A).
T7836 747-1033 Sentence denotes After digestion with HpaII and Bsp143II a sufficient PCR amplification of F1 and F2 was detected in DNA from IRF-4-negative Jurkat, CML-T1, U-937, K-562 and EM-2 cells, suggesting a promoter methylation (and restriction protection) at the respective recognition sites (Figure 3B and C).
T7837 1034-1169 Sentence denotes Notably, in IRF-4-positive SD-1 cells digestion with the methylation-sensitive enzymes completely inhibited amplification of F1 and F2.
T7838 1170-1366 Sentence denotes In IRF-4-positive BV-173 cells a HpaII, but not a Bsh1236I digestion, significantly reduced the amplifiable DNA message of F2 (Figure 3C), whereas amplification of F1 was not affected (Figure 3B).
T7839 1367-1562 Sentence denotes This implied that IRF-4 transcription in SD-1 and BV-173 cells is associated with less promoter methylation (in BV-173 especially at HpaII sites) as compared with the tested IRF-4-negative cells.
T120 0-100 Sentence denotes Methylation-sensitive enzymes do not cut specific sites in the IRF-4 promoter in hematopoietic cells
T121 101-340 Sentence denotes To further investigate promoter methylation as a regulatory mechanism of IRF-4 gene expression, restriction-PCR-assays were performed (20,24), where only methylated DNA would not be cut enabling subsequent PCR amplification and vice versa.
T122 341-518 Sentence denotes Genomic DNA from leukemic cells Jurkat, CML-T1, U-937, K-562, EM-2 and BV-173 was digested with the methylation-sensitive enzymes HpaII, Bsh1236I and HaeII-isochizomer Bsp143II.
T123 519-644 Sentence denotes EcoRI, which has no recognition site within the IRF-4 promoter, and the methylation-resistant enzyme MspI served as controls.
T124 645-746 Sentence denotes Two separate amplification reactions were performed, generating two fragments, F1 and F2 (Figure 3A).
T125 747-1033 Sentence denotes After digestion with HpaII and Bsp143II a sufficient PCR amplification of F1 and F2 was detected in DNA from IRF-4-negative Jurkat, CML-T1, U-937, K-562 and EM-2 cells, suggesting a promoter methylation (and restriction protection) at the respective recognition sites (Figure 3B and C).
T126 1034-1169 Sentence denotes Notably, in IRF-4-positive SD-1 cells digestion with the methylation-sensitive enzymes completely inhibited amplification of F1 and F2.
T127 1170-1366 Sentence denotes In IRF-4-positive BV-173 cells a HpaII, but not a Bsh1236I digestion, significantly reduced the amplifiable DNA message of F2 (Figure 3C), whereas amplification of F1 was not affected (Figure 3B).
T128 1367-1562 Sentence denotes This implied that IRF-4 transcription in SD-1 and BV-173 cells is associated with less promoter methylation (in BV-173 especially at HpaII sites) as compared with the tested IRF-4-negative cells.

2_test

Id Subject Object Predicate Lexical cue
16396836-7938018-76538195 236-238 7938018 denotes 20
16396836-9389709-76538196 239-241 9389709 denotes 24

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T7852 0-21 JJ denotes Methylation-sensitive
T7853 22-29 NN denotes enzymes
T7854 30-32 VB denotes do
T7855 33-36 RB denotes not
T7856 37-40 VB denotes cut
T7857 41-49 JJ denotes specific
T7858 50-55 NN denotes sites
T7859 56-58 IN denotes in
T7860 59-62 DT denotes the
T7861 63-68 NN denotes IRF-4
T7862 69-77 NN denotes promoter
T7863 78-80 IN denotes in
T7864 81-94 JJ denotes hematopoietic
T7865 95-100 NN denotes cells
T7866 101-103 TO denotes To
T7867 104-111 RB denotes further
T7868 112-123 VB denotes investigate
T7869 124-132 NN denotes promoter
T7870 133-144 NN denotes methylation
T7871 145-147 IN denotes as
T7872 148-149 DT denotes a
T7873 150-160 JJ denotes regulatory
T7874 161-170 NN denotes mechanism
T7875 171-173 IN denotes of
T7876 174-179 NN denotes IRF-4
T7877 180-184 NN denotes gene
T7878 185-195 NN denotes expression
T7879 195-196 -COMMA- denotes ,
T7880 197-219 NN denotes restriction-PCR-assays
T7881 220-224 VB denotes were
T7882 225-234 VB denotes performed
T7883 235-236 -LRB- denotes (
T7884 236-241 CD denotes 20,24
T7885 241-242 -RRB- denotes )
T7886 242-243 -COMMA- denotes ,
T7887 244-249 WRB denotes where
T7888 250-254 RB denotes only
T7889 255-265 VB denotes methylated
T7890 266-269 NN denotes DNA
T7891 270-275 MD denotes would
T7892 276-279 RB denotes not
T7893 280-282 VB denotes be
T7894 283-286 VB denotes cut
T7895 287-295 VB denotes enabling
T7896 296-306 JJ denotes subsequent
T7897 307-310 NN denotes PCR
T7898 311-324 NN denotes amplification
T7899 325-328 CC denotes and
T7900 329-333 NN denotes vice
T7901 334-339 NN denotes versa
T7902 341-348 JJ denotes Genomic
T7903 349-352 NN denotes DNA
T7904 353-357 IN denotes from
T7905 358-366 JJ denotes leukemic
T7906 367-372 NN denotes cells
T7907 373-379 NN denotes Jurkat
T7908 379-380 -COMMA- denotes ,
T7909 381-387 NN denotes CML-T1
T7910 387-388 -COMMA- denotes ,
T7911 389-394 NN denotes U-937
T7912 394-395 -COMMA- denotes ,
T7913 396-401 NN denotes K-562
T7914 401-402 -COMMA- denotes ,
T7915 403-407 NN denotes EM-2
T7916 408-411 CC denotes and
T7917 412-418 NN denotes BV-173
T7918 419-422 VB denotes was
T7919 423-431 VB denotes digested
T7920 432-436 IN denotes with
T7921 437-440 DT denotes the
T7922 441-462 JJ denotes methylation-sensitive
T7923 463-470 NN denotes enzymes
T7924 471-476 NN denotes HpaII
T7925 476-477 -COMMA- denotes ,
T7926 478-486 NN denotes Bsh1236I
T7927 487-490 CC denotes and
T7928 491-508 NN denotes HaeII-isochizomer
T7929 509-517 NN denotes Bsp143II
T7930 519-524 NNP denotes EcoRI
T7931 524-525 -COMMA- denotes ,
T7932 526-531 WDT denotes which
T7933 532-535 VB denotes has
T7934 536-538 DT denotes no
T7935 539-550 NN denotes recognition
T7936 551-555 NN denotes site
T7937 556-562 IN denotes within
T7938 563-566 DT denotes the
T7939 567-572 NN denotes IRF-4
T7940 573-581 NN denotes promoter
T7941 581-582 -COMMA- denotes ,
T7942 583-586 CC denotes and
T7943 587-590 DT denotes the
T7944 591-612 JJ denotes methylation-resistant
T7945 613-619 NN denotes enzyme
T7946 620-624 NN denotes MspI
T7947 625-631 VB denotes served
T7948 632-634 IN denotes as
T7949 635-643 NN denotes controls
T7950 645-648 CD denotes Two
T7951 649-657 JJ denotes separate
T7952 658-671 NN denotes amplification
T7953 672-681 NN denotes reactions
T7954 682-686 VB denotes were
T7955 687-696 VB denotes performed
T7956 696-697 -COMMA- denotes ,
T7957 698-708 VB denotes generating
T7958 709-712 CD denotes two
T7959 713-722 NN denotes fragments
T7960 722-723 -COMMA- denotes ,
T7961 724-726 NN denotes F1
T7962 727-730 CC denotes and
T7963 731-733 NN denotes F2
T7964 734-735 -LRB- denotes (
T7965 735-741 NN denotes Figure
T7966 742-744 NN denotes 3A
T7967 744-745 -RRB- denotes )
T7968 747-752 IN denotes After
T7969 753-762 NN denotes digestion
T7970 763-767 IN denotes with
T7971 768-773 NN denotes HpaII
T7972 774-777 CC denotes and
T7973 778-786 NN denotes Bsp143II
T7974 787-788 DT denotes a
T7975 789-799 JJ denotes sufficient
T7976 800-803 NN denotes PCR
T7977 804-817 NN denotes amplification
T7978 818-820 IN denotes of
T7979 821-823 NN denotes F1
T7980 824-827 CC denotes and
T7981 828-830 NN denotes F2
T7982 831-834 VB denotes was
T7983 835-843 VB denotes detected
T7984 844-846 IN denotes in
T7985 847-850 NN denotes DNA
T7986 851-855 IN denotes from
T7987 856-870 JJ denotes IRF-4-negative
T7988 871-877 NN denotes Jurkat
T7989 877-878 -COMMA- denotes ,
T7990 879-885 NN denotes CML-T1
T7991 885-886 -COMMA- denotes ,
T7992 887-892 NN denotes U-937
T7993 892-893 -COMMA- denotes ,
T7994 894-899 NN denotes K-562
T7995 900-903 CC denotes and
T7996 904-908 NN denotes EM-2
T7997 909-914 NN denotes cells
T7998 914-915 -COMMA- denotes ,
T7999 916-926 VB denotes suggesting
T8000 927-928 DT denotes a
T8001 929-937 NN denotes promoter
T8002 938-949 NN denotes methylation
T8003 950-951 -LRB- denotes (
T8004 951-954 CC denotes and
T8005 955-966 NN denotes restriction
T8006 967-977 NN denotes protection
T8007 977-978 -RRB- denotes )
T8008 979-981 IN denotes at
T8009 982-985 DT denotes the
T8010 986-996 JJ denotes respective
T8011 997-1008 NN denotes recognition
T8012 1009-1014 NN denotes sites
T8013 1015-1016 -LRB- denotes (
T8014 1016-1022 NN denotes Figure
T8015 1023-1025 NN denotes 3B
T8016 1026-1029 CC denotes and
T8017 1030-1031 NN denotes C
T8018 1031-1032 -RRB- denotes )
T8019 1034-1041 RB denotes Notably
T8020 1041-1042 -COMMA- denotes ,
T8021 1043-1045 IN denotes in
T8022 1046-1060 JJ denotes IRF-4-positive
T8023 1061-1065 NN denotes SD-1
T8024 1066-1071 NN denotes cells
T8025 1072-1081 NN denotes digestion
T8026 1082-1086 IN denotes with
T8027 1087-1090 DT denotes the
T8028 1091-1112 JJ denotes methylation-sensitive
T8029 1113-1120 NN denotes enzymes
T8030 1121-1131 RB denotes completely
T8031 1132-1141 VB denotes inhibited
T8032 1142-1155 NN denotes amplification
T8033 1156-1158 IN denotes of
T8034 1159-1161 NN denotes F1
T8035 1162-1165 CC denotes and
T8036 1166-1168 NN denotes F2
T8037 1170-1172 IN denotes In
T8038 1173-1187 JJ denotes IRF-4-positive
T8039 1188-1194 NN denotes BV-173
T8040 1195-1200 NN denotes cells
T8041 1201-1202 DT denotes a
T8042 1203-1208 NN denotes HpaII
T8043 1208-1209 -COMMA- denotes ,
T8044 1210-1213 CC denotes but
T8045 1214-1217 RB denotes not
T8046 1218-1219 DT denotes a
T8047 1220-1228 NN denotes Bsh1236I
T8048 1229-1238 NN denotes digestion
T8049 1238-1239 -COMMA- denotes ,
T8050 1240-1253 RB denotes significantly
T8051 1254-1261 VB denotes reduced
T8052 1262-1265 DT denotes the
T8053 1266-1277 JJ denotes amplifiable
T8054 1278-1281 NN denotes DNA
T8055 1282-1289 NN denotes message
T8056 1290-1292 IN denotes of
T8057 1293-1295 NN denotes F2
T8058 1296-1297 -LRB- denotes (
T8059 1297-1303 NN denotes Figure
T8060 1304-1306 NN denotes 3C
T8061 1306-1307 -RRB- denotes )
T8062 1307-1308 -COMMA- denotes ,
T8063 1309-1316 IN denotes whereas
T8064 1317-1330 NN denotes amplification
T8065 1331-1333 IN denotes of
T8066 1334-1336 NN denotes F1
T8067 1337-1340 VB denotes was
T8068 1341-1344 RB denotes not
T8069 1345-1353 VB denotes affected
T8070 1354-1355 -LRB- denotes (
T8071 1355-1361 NN denotes Figure
T8072 1362-1364 NN denotes 3B
T8073 1364-1365 -RRB- denotes )
T8074 1367-1371 DT denotes This
T8075 1372-1379 VB denotes implied
T8076 1380-1384 IN denotes that
T8077 1385-1390 NN denotes IRF-4
T8078 1391-1404 NN denotes transcription
T8079 1405-1407 IN denotes in
T8080 1408-1412 NN denotes SD-1
T8081 1413-1416 CC denotes and
T8082 1417-1423 NN denotes BV-173
T8083 1424-1429 NN denotes cells
T8084 1430-1432 VB denotes is
T8085 1433-1443 VB denotes associated
T8086 1444-1448 IN denotes with
T8087 1449-1453 JJ denotes less
T8088 1454-1462 NN denotes promoter
T8089 1463-1474 NN denotes methylation
T8090 1475-1476 -LRB- denotes (
T8091 1476-1478 IN denotes in
T8092 1479-1485 NN denotes BV-173
T8093 1486-1496 RB denotes especially
T8094 1497-1499 IN denotes at
T8095 1500-1505 NN denotes HpaII
T8096 1506-1511 NN denotes sites
T8097 1511-1512 -RRB- denotes )
T8098 1513-1515 IN denotes as
T8099 1516-1524 VB denotes compared
T8100 1525-1529 IN denotes with
T8101 1530-1533 DT denotes the
T8102 1534-1540 VB denotes tested
T8103 1541-1555 JJ denotes IRF-4-negative
T8104 1556-1561 NN denotes cells
R6497 T7853 T7852 arg1Of enzymes,Methylation-sensitive
R6498 T7853 T7854 arg1Of enzymes,do
R6499 T7853 T7856 arg1Of enzymes,cut
R6500 T7856 T7854 arg2Of cut,do
R6501 T7856 T7855 arg1Of cut,not
R6502 T7858 T7856 arg2Of sites,cut
R6503 T7858 T7857 arg1Of sites,specific
R6504 T7858 T7859 arg1Of sites,in
R6505 T7862 T7859 arg2Of promoter,in
R6506 T7862 T7860 arg1Of promoter,the
R6507 T7862 T7861 arg1Of promoter,IRF-4
R6508 T7862 T7863 arg1Of promoter,in
R6509 T7865 T7863 arg2Of cells,in
R6510 T7865 T7864 arg1Of cells,hematopoietic
R6511 T7868 T7866 arg1Of investigate,To
R6512 T7868 T7867 arg1Of investigate,further
R6513 T7868 T7871 arg1Of investigate,as
R6514 T7870 T7868 arg2Of methylation,investigate
R6515 T7870 T7869 arg1Of methylation,promoter
R6516 T7874 T7871 arg2Of mechanism,as
R6517 T7874 T7872 arg1Of mechanism,a
R6518 T7874 T7873 arg1Of mechanism,regulatory
R6519 T7874 T7875 arg1Of mechanism,of
R6520 T7878 T7875 arg2Of expression,of
R6521 T7878 T7876 arg1Of expression,IRF-4
R6522 T7878 T7877 arg1Of expression,gene
R6523 T7880 T7868 arg1Of restriction-PCR-assays,investigate
R6524 T7880 T7881 arg1Of restriction-PCR-assays,were
R6525 T7880 T7882 arg2Of restriction-PCR-assays,performed
R6526 T7882 T7866 modOf performed,To
R6527 T7882 T7879 arg1Of performed,","
R6528 T7882 T7881 arg2Of performed,were
R6529 T7882 T7883 arg1Of performed,(
R6530 T7882 T7886 arg1Of performed,","
R6531 T7882 T7887 arg1Of performed,where
R6532 T7884 T7883 arg2Of "20,24",(
R6533 T7885 T7883 arg3Of ),(
R6534 T7890 T7888 arg1Of DNA,only
R6535 T7890 T7889 arg2Of DNA,methylated
R6536 T7890 T7891 arg1Of DNA,would
R6537 T7890 T7893 arg1Of DNA,be
R6538 T7890 T7894 arg2Of DNA,cut
R6539 T7890 T7895 arg1Of DNA,enabling
R6540 T7894 T7887 arg2Of cut,where
R6541 T7894 T7891 arg2Of cut,would
R6542 T7894 T7892 arg1Of cut,not
R6543 T7894 T7893 arg2Of cut,be
R6544 T7894 T7895 modOf cut,enabling
R6545 T7898 T7896 arg1Of amplification,subsequent
R6546 T7898 T7897 arg1Of amplification,PCR
R6547 T7898 T7899 arg1Of amplification,and
R6548 T7899 T7895 arg2Of and,enabling
R6549 T7901 T7899 arg2Of versa,and
R6550 T7901 T7900 arg1Of versa,vice
R6551 T7903 T7902 arg1Of DNA,Genomic
R6552 T7903 T7904 arg1Of DNA,from
R6553 T7903 T7918 arg1Of DNA,was
R6554 T7903 T7919 arg2Of DNA,digested
R6555 T7906 T7905 arg1Of cells,leukemic
R6556 T7907 T7908 arg1Of Jurkat,","
R6557 T7908 T7910 arg1Of ",",","
R6558 T7909 T7908 arg2Of CML-T1,","
R6559 T7910 T7912 arg1Of ",",","
R6560 T7911 T7910 arg2Of U-937,","
R6561 T7912 T7914 arg1Of ",",","
R6562 T7913 T7912 arg2Of K-562,","
R6563 T7914 T7906 arg1Of ",",cells
R6564 T7914 T7916 arg1Of ",",and
R6565 T7915 T7914 arg2Of EM-2,","
R6566 T7916 T7904 arg2Of and,from
R6567 T7917 T7916 arg2Of BV-173,and
R6568 T7919 T7918 arg2Of digested,was
R6569 T7919 T7920 arg1Of digested,with
R6570 T7923 T7921 arg1Of enzymes,the
R6571 T7923 T7922 arg1Of enzymes,methylation-sensitive
R6572 T7924 T7925 arg1Of HpaII,","
R6573 T7925 T7927 arg1Of ",",and
R6574 T7926 T7925 arg2Of Bsh1236I,","
R6575 T7927 T7920 arg2Of and,with
R6576 T7927 T7923 arg1Of and,enzymes
R6577 T7929 T7927 arg2Of Bsp143II,and
R6578 T7929 T7928 arg1Of Bsp143II,HaeII-isochizomer
R6579 T7930 T7931 arg1Of EcoRI,","
R6580 T7930 T7932 arg1Of EcoRI,which
R6581 T7930 T7933 arg1Of EcoRI,has
R6582 T7936 T7934 arg1Of site,no
R6583 T7936 T7935 arg1Of site,recognition
R6584 T7936 T7937 arg1Of site,within
R6585 T7936 T7942 arg1Of site,and
R6586 T7940 T7937 arg2Of promoter,within
R6587 T7940 T7938 arg1Of promoter,the
R6588 T7940 T7939 arg1Of promoter,IRF-4
R6589 T7942 T7933 arg2Of and,has
R6590 T7942 T7941 arg1Of and,","
R6591 T7946 T7942 arg2Of MspI,and
R6592 T7946 T7943 arg1Of MspI,the
R6593 T7946 T7944 arg1Of MspI,methylation-resistant
R6594 T7946 T7945 arg1Of MspI,enzyme
R6595 T7946 T7947 arg2Of MspI,served
R6596 T7947 T7948 arg1Of served,as
R6597 T7949 T7948 arg2Of controls,as
R6598 T7953 T7950 arg1Of reactions,Two
R6599 T7953 T7951 arg1Of reactions,separate
R6600 T7953 T7952 arg1Of reactions,amplification
R6601 T7953 T7954 arg1Of reactions,were
R6602 T7953 T7955 arg2Of reactions,performed
R6603 T7955 T7954 arg2Of performed,were
R6604 T7955 T7956 arg1Of performed,","
R6605 T7955 T7957 modOf performed,generating
R6606 T7959 T7957 arg2Of fragments,generating
R6607 T7959 T7958 arg1Of fragments,two
R6608 T7959 T7960 arg1Of fragments,","
R6609 T7961 T7962 arg1Of F1,and
R6610 T7962 T7960 arg2Of and,","
R6611 T7962 T7964 arg1Of and,(
R6612 T7963 T7962 arg2Of F2,and
R6613 T7966 T7964 arg2Of 3A,(
R6614 T7966 T7965 arg1Of 3A,Figure
R6615 T7967 T7964 arg3Of ),(
R6616 T7969 T7968 arg2Of digestion,After
R6617 T7969 T7970 arg1Of digestion,with
R6618 T7971 T7972 arg1Of HpaII,and
R6619 T7972 T7970 arg2Of and,with
R6620 T7973 T7972 arg2Of Bsp143II,and
R6621 T7977 T7974 arg1Of amplification,a
R6622 T7977 T7975 arg1Of amplification,sufficient
R6623 T7977 T7976 arg1Of amplification,PCR
R6624 T7977 T7978 arg1Of amplification,of
R6625 T7977 T7982 arg1Of amplification,was
R6626 T7977 T7983 arg2Of amplification,detected
R6627 T7979 T7980 arg1Of F1,and
R6628 T7980 T7978 arg2Of and,of
R6629 T7981 T7980 arg2Of F2,and
R6630 T7983 T7968 arg1Of detected,After
R6631 T7983 T7982 arg2Of detected,was
R6632 T7983 T7984 arg1Of detected,in
R6633 T7983 T7986 arg1Of detected,from
R6634 T7983 T7998 arg1Of detected,","
R6635 T7983 T7999 modOf detected,suggesting
R6636 T7985 T7984 arg2Of DNA,in
R6637 T7988 T7987 arg1Of Jurkat,IRF-4-negative
R6638 T7988 T7989 arg1Of Jurkat,","
R6639 T7989 T7991 arg1Of ",",","
R6640 T7990 T7989 arg2Of CML-T1,","
R6641 T7991 T7993 arg1Of ",",","
R6642 T7992 T7991 arg2Of U-937,","
R6643 T7993 T7995 arg1Of ",",and
R6644 T7994 T7993 arg2Of K-562,","
R6645 T7995 T7986 arg2Of and,from
R6646 T7997 T7995 arg2Of cells,and
R6647 T7997 T7996 arg1Of cells,EM-2
R6648 T8002 T7999 arg2Of methylation,suggesting
R6649 T8002 T8000 arg1Of methylation,a
R6650 T8002 T8001 arg1Of methylation,promoter
R6651 T8002 T8003 arg1Of methylation,(
R6652 T8002 T8008 arg1Of methylation,at
R6653 T8006 T8003 arg2Of protection,(
R6654 T8006 T8004 arg1Of protection,and
R6655 T8006 T8005 arg1Of protection,restriction
R6656 T8007 T8003 arg3Of ),(
R6657 T8012 T8008 arg2Of sites,at
R6658 T8012 T8009 arg1Of sites,the
R6659 T8012 T8010 arg1Of sites,respective
R6660 T8012 T8011 arg1Of sites,recognition
R6661 T8012 T8013 arg1Of sites,(
R6662 T8015 T8014 arg1Of 3B,Figure
R6663 T8015 T8016 arg1Of 3B,and
R6664 T8016 T8013 arg2Of and,(
R6665 T8017 T8016 arg2Of C,and
R6666 T8018 T8013 arg3Of ),(
R6667 T8024 T8021 arg2Of cells,in
R6668 T8024 T8022 arg1Of cells,IRF-4-positive
R6669 T8024 T8023 arg1Of cells,SD-1
R6670 T8025 T8026 arg1Of digestion,with
R6671 T8025 T8031 arg1Of digestion,inhibited
R6672 T8029 T8026 arg2Of enzymes,with
R6673 T8029 T8027 arg1Of enzymes,the
R6674 T8029 T8028 arg1Of enzymes,methylation-sensitive
R6675 T8031 T8019 arg1Of inhibited,Notably
R6676 T8031 T8020 arg1Of inhibited,","
R6677 T8031 T8021 arg1Of inhibited,in
R6678 T8031 T8030 arg1Of inhibited,completely
R6679 T8032 T8031 arg2Of amplification,inhibited
R6680 T8032 T8033 arg1Of amplification,of
R6681 T8034 T8035 arg1Of F1,and
R6682 T8035 T8033 arg2Of and,of
R6683 T8036 T8035 arg2Of F2,and
R6684 T8040 T8037 arg2Of cells,In
R6685 T8040 T8038 arg1Of cells,IRF-4-positive
R6686 T8040 T8039 arg1Of cells,BV-173
R6687 T8042 T8041 arg1Of HpaII,a
R6688 T8042 T8044 arg1Of HpaII,but
R6689 T8044 T8043 arg1Of but,","
R6690 T8044 T8045 arg1Of but,not
R6691 T8044 T8051 arg1Of but,reduced
R6692 T8048 T8044 arg2Of digestion,but
R6693 T8048 T8046 arg1Of digestion,a
R6694 T8048 T8047 arg1Of digestion,Bsh1236I
R6695 T8051 T8049 arg1Of reduced,","
R6696 T8051 T8050 arg1Of reduced,significantly
R6697 T8051 T8063 arg1Of reduced,whereas
R6698 T8055 T8051 arg2Of message,reduced
R6699 T8055 T8052 arg1Of message,the
R6700 T8055 T8053 arg1Of message,amplifiable
R6701 T8055 T8054 arg1Of message,DNA
R6702 T8055 T8056 arg1Of message,of
R6703 T8057 T8056 arg2Of F2,of
R6704 T8057 T8058 arg1Of F2,(
R6705 T8060 T8058 arg2Of 3C,(
R6706 T8060 T8059 arg1Of 3C,Figure
R6707 T8061 T8058 arg3Of ),(
R6708 T8063 T8037 arg1Of whereas,In
R6709 T8063 T8062 arg1Of whereas,","
R6710 T8064 T8065 arg1Of amplification,of
R6711 T8064 T8067 arg1Of amplification,was
R6712 T8064 T8069 arg2Of amplification,affected
R6713 T8066 T8065 arg2Of F1,of
R6714 T8069 T8063 arg2Of affected,whereas
R6715 T8069 T8067 arg2Of affected,was
R6716 T8069 T8068 arg1Of affected,not
R6717 T8069 T8070 arg1Of affected,(
R6718 T8072 T8070 arg2Of 3B,(
R6719 T8072 T8071 arg1Of 3B,Figure
R6720 T8073 T8070 arg3Of ),(
R6721 T8074 T8075 arg1Of This,implied
R6722 T8078 T8077 arg1Of transcription,IRF-4
R6723 T8078 T8079 arg1Of transcription,in
R6724 T8078 T8084 arg1Of transcription,is
R6725 T8078 T8085 arg2Of transcription,associated
R6726 T8080 T8081 arg1Of SD-1,and
R6727 T8082 T8081 arg2Of BV-173,and
R6728 T8083 T8079 arg2Of cells,in
R6729 T8083 T8080 arg1Of cells,SD-1
R6730 T8083 T8082 arg1Of cells,BV-173
R6731 T8085 T8075 arg2Of associated,implied
R6732 T8085 T8076 arg1Of associated,that
R6733 T8085 T8084 arg2Of associated,is
R6734 T8085 T8086 arg1Of associated,with
R6735 T8085 T8090 arg1Of associated,(
R6736 T8085 T8098 arg1Of associated,as
R6737 T8089 T8086 arg2Of methylation,with
R6738 T8089 T8087 arg1Of methylation,less
R6739 T8089 T8088 arg1Of methylation,promoter
R6740 T8091 T8090 arg2Of in,(
R6741 T8092 T8091 arg2Of BV-173,in
R6742 T8092 T8094 arg1Of BV-173,at
R6743 T8094 T8093 arg1Of at,especially
R6744 T8096 T8094 arg2Of sites,at
R6745 T8096 T8095 arg1Of sites,HpaII
R6746 T8097 T8090 arg3Of ),(
R6747 T8099 T8098 arg2Of compared,as
R6748 T8099 T8100 arg1Of compared,with
R6749 T8104 T8100 arg2Of cells,with
R6750 T8104 T8101 arg1Of cells,the
R6751 T8104 T8102 arg2Of cells,tested
R6752 T8104 T8103 arg1Of cells,IRF-4-negative

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T8113 0-21 JJ denotes Methylation-sensitive
T8114 22-29 NNS denotes enzymes
T8115 30-32 VBP denotes do
T8116 33-36 RB denotes not
T8117 37-40 VB denotes cut
T8118 41-49 JJ denotes specific
T8119 50-55 NNS denotes sites
T8120 56-58 IN denotes in
T8121 59-62 DT denotes the
T8122 63-68 NN denotes IRF-4
T8123 69-77 NN denotes promoter
T8124 78-80 IN denotes in
T8125 81-94 JJ denotes hematopoietic
T8126 95-100 NNS denotes cells
T8127 101-103 TO denotes To
T8128 104-111 RBR denotes further
T8129 112-123 VB denotes investigate
T8130 124-132 NN denotes promoter
T8131 133-144 NN denotes methylation
T8132 145-147 IN denotes as
T8133 148-149 DT denotes a
T8134 150-160 JJ denotes regulatory
T8135 161-170 NN denotes mechanism
T8136 171-173 IN denotes of
T8137 174-179 NNP denotes IRF-4
T8138 180-184 NN denotes gene
T8139 185-195 NN denotes expression
T8140 195-196 , denotes ,
T8141 197-219 NNPS denotes restriction-PCR-assays
T8142 220-224 VBD denotes were
T8143 225-234 VBN denotes performed
T8144 235-236 -LRB- denotes (
T8145 236-241 CD denotes 20,24
T8146 241-242 -RRB- denotes )
T8147 242-243 , denotes ,
T8148 244-249 WRB denotes where
T8149 250-254 RB denotes only
T8150 255-265 JJ denotes methylated
T8151 266-269 NN denotes DNA
T8152 270-275 MD denotes would
T8153 276-279 RB denotes not
T8154 280-282 VB denotes be
T8155 283-286 VBN denotes cut
T8156 287-295 VBG denotes enabling
T8157 296-306 JJ denotes subsequent
T8158 307-310 NNP denotes PCR
T8159 311-324 NN denotes amplification
T8160 325-328 CC denotes and
T8161 329-333 NN denotes vice
T8162 334-339 RB denotes versa
T8163 339-340 . denotes .
T8164 341-348 NNP denotes Genomic
T8165 349-352 NNP denotes DNA
T8166 353-357 IN denotes from
T8167 358-366 JJ denotes leukemic
T8168 367-372 NNS denotes cells
T8169 373-379 NNP denotes Jurkat
T8170 379-380 , denotes ,
T8171 381-387 NNP denotes CML-T1
T8172 387-388 , denotes ,
T8173 389-394 NNP denotes U-937
T8174 394-395 , denotes ,
T8175 396-401 NNP denotes K-562
T8176 401-402 , denotes ,
T8177 403-407 NNP denotes EM-2
T8178 408-411 CC denotes and
T8179 412-418 NNP denotes BV-173
T8180 419-422 VBD denotes was
T8181 423-431 VBN denotes digested
T8182 432-436 IN denotes with
T8183 437-440 DT denotes the
T8184 441-462 JJ denotes methylation-sensitive
T8185 463-470 NNS denotes enzymes
T8186 471-476 NNP denotes HpaII
T8187 476-477 , denotes ,
T8188 478-486 NNP denotes Bsh1236I
T8189 487-490 CC denotes and
T8190 491-508 NNP denotes HaeII-isochizomer
T8191 509-517 NNP denotes Bsp143II
T8192 517-518 . denotes .
T8193 519-524 NNP denotes EcoRI
T8194 524-525 , denotes ,
T8195 526-531 WDT denotes which
T8196 532-535 VBZ denotes has
T8197 536-538 DT denotes no
T8198 539-550 NN denotes recognition
T8199 551-555 NN denotes site
T8200 556-562 IN denotes within
T8201 563-566 DT denotes the
T8202 567-572 NN denotes IRF-4
T8203 573-581 NN denotes promoter
T8204 581-582 , denotes ,
T8205 583-586 CC denotes and
T8206 587-590 DT denotes the
T8207 591-612 JJ denotes methylation-resistant
T8208 613-619 NN denotes enzyme
T8209 620-624 NNP denotes MspI
T8210 625-631 VBD denotes served
T8211 632-634 IN denotes as
T8212 635-643 NNS denotes controls
T8213 643-644 . denotes .
T8214 645-648 CD denotes Two
T8215 649-657 JJ denotes separate
T8216 658-671 NN denotes amplification
T8217 672-681 NNS denotes reactions
T8218 682-686 VBD denotes were
T8219 687-696 VBN denotes performed
T8220 696-697 , denotes ,
T8221 698-708 VBG denotes generating
T8222 709-712 CD denotes two
T8223 713-722 NNS denotes fragments
T8224 722-723 , denotes ,
T8225 724-726 NNP denotes F1
T8226 727-730 CC denotes and
T8227 731-733 NNP denotes F2
T8228 734-735 -LRB- denotes (
T8229 735-741 NNP denotes Figure
T8230 742-744 NNP denotes 3A
T8231 744-745 -RRB- denotes )
T8232 745-746 . denotes .
T8233 747-752 IN denotes After
T8234 753-762 NN denotes digestion
T8235 763-767 IN denotes with
T8236 768-773 NNP denotes HpaII
T8237 774-777 CC denotes and
T8238 778-786 NNP denotes Bsp143II
T8239 787-788 DT denotes a
T8240 789-799 JJ denotes sufficient
T8241 800-803 NNP denotes PCR
T8242 804-817 NN denotes amplification
T8243 818-820 IN denotes of
T8244 821-823 CD denotes F1
T8245 824-827 CC denotes and
T8246 828-830 CD denotes F2
T8247 831-834 VBD denotes was
T8248 835-843 VBN denotes detected
T8249 844-846 IN denotes in
T8250 847-850 NNP denotes DNA
T8251 851-855 IN denotes from
T8252 856-870 JJ denotes IRF-4-negative
T8253 871-877 NNP denotes Jurkat
T8254 877-878 , denotes ,
T8255 879-885 NNP denotes CML-T1
T8256 885-886 , denotes ,
T8257 887-892 NNP denotes U-937
T8258 892-893 , denotes ,
T8259 894-899 NNP denotes K-562
T8260 900-903 CC denotes and
T8261 904-908 NNP denotes EM-2
T8262 909-914 NNS denotes cells
T8263 914-915 , denotes ,
T8264 916-926 VBG denotes suggesting
T8265 927-928 DT denotes a
T8266 929-937 NN denotes promoter
T8267 938-949 NN denotes methylation
T8268 950-951 -LRB- denotes (
T8269 951-954 CC denotes and
T8270 955-966 NN denotes restriction
T8271 967-977 NN denotes protection
T8272 977-978 -RRB- denotes )
T8273 979-981 IN denotes at
T8274 982-985 DT denotes the
T8275 986-996 JJ denotes respective
T8276 997-1008 NN denotes recognition
T8277 1009-1014 NNS denotes sites
T8278 1015-1016 -LRB- denotes (
T8279 1016-1022 NN denotes Figure
T8280 1023-1025 NN denotes 3B
T8281 1026-1029 CC denotes and
T8282 1030-1031 NNP denotes C
T8283 1031-1032 -RRB- denotes )
T8284 1032-1033 . denotes .
T8285 1034-1041 RB denotes Notably
T8286 1041-1042 , denotes ,
T8287 1043-1045 IN denotes in
T8288 1046-1060 JJ denotes IRF-4-positive
T8289 1061-1065 NN denotes SD-1
T8290 1066-1071 NNS denotes cells
T8291 1072-1081 NN denotes digestion
T8292 1082-1086 IN denotes with
T8293 1087-1090 DT denotes the
T8294 1091-1112 JJ denotes methylation-sensitive
T8295 1113-1120 NNS denotes enzymes
T8296 1121-1131 RB denotes completely
T8297 1132-1141 VBD denotes inhibited
T8298 1142-1155 NN denotes amplification
T8299 1156-1158 IN denotes of
T8300 1159-1161 CD denotes F1
T8301 1162-1165 CC denotes and
T8302 1166-1168 CD denotes F2
T8303 1168-1169 . denotes .
T8304 1170-1172 IN denotes In
T8305 1173-1187 JJ denotes IRF-4-positive
T8306 1188-1194 JJ denotes BV-173
T8307 1195-1200 NNS denotes cells
T8308 1201-1202 DT denotes a
T8309 1203-1208 NNP denotes HpaII
T8310 1208-1209 , denotes ,
T8311 1210-1213 CC denotes but
T8312 1214-1217 RB denotes not
T8313 1218-1219 DT denotes a
T8314 1220-1228 JJ denotes Bsh1236I
T8315 1229-1238 NN denotes digestion
T8316 1238-1239 , denotes ,
T8317 1240-1253 RB denotes significantly
T8318 1254-1261 VBD denotes reduced
T8319 1262-1265 DT denotes the
T8320 1266-1277 JJ denotes amplifiable
T8321 1278-1281 NNP denotes DNA
T8322 1282-1289 NN denotes message
T8323 1290-1292 IN denotes of
T8324 1293-1295 CD denotes F2
T8325 1296-1297 -LRB- denotes (
T8326 1297-1303 NN denotes Figure
T8327 1304-1306 NN denotes 3C
T8328 1306-1307 -RRB- denotes )
T8329 1307-1308 , denotes ,
T8330 1309-1316 IN denotes whereas
T8331 1317-1330 NN denotes amplification
T8332 1331-1333 IN denotes of
T8333 1334-1336 CD denotes F1
T8334 1337-1340 VBD denotes was
T8335 1341-1344 RB denotes not
T8336 1345-1353 VBN denotes affected
T8337 1354-1355 -LRB- denotes (
T8338 1355-1361 NN denotes Figure
T8339 1362-1364 NN denotes 3B
T8340 1364-1365 -RRB- denotes )
T8341 1365-1366 . denotes .
T8342 1367-1371 DT denotes This
T8343 1372-1379 VBD denotes implied
T8344 1380-1384 IN denotes that
T8345 1385-1390 JJ denotes IRF-4
T8346 1391-1404 NN denotes transcription
T8347 1405-1407 IN denotes in
T8348 1408-1412 NN denotes SD-1
T8349 1413-1416 CC denotes and
T8350 1417-1423 JJ denotes BV-173
T8351 1424-1429 NNS denotes cells
T8352 1430-1432 VBZ denotes is
T8353 1433-1443 VBN denotes associated
T8354 1444-1448 IN denotes with
T8355 1449-1453 JJR denotes less
T8356 1454-1462 NN denotes promoter
T8357 1463-1474 NN denotes methylation
T8358 1475-1476 -LRB- denotes (
T8359 1476-1478 IN denotes in
T8360 1479-1485 NN denotes BV-173
T8361 1486-1496 RB denotes especially
T8362 1497-1499 IN denotes at
T8363 1500-1505 NNP denotes HpaII
T8364 1506-1511 NNS denotes sites
T8365 1511-1512 -RRB- denotes )
T8366 1513-1515 IN denotes as
T8367 1516-1524 VBN denotes compared
T8368 1525-1529 IN denotes with
T8369 1530-1533 DT denotes the
T8370 1534-1540 VBN denotes tested
T8371 1541-1555 JJ denotes IRF-4-negative
T8372 1556-1561 NNS denotes cells
T8373 1561-1562 . denotes .
R6753 T8113 T8114 amod Methylation-sensitive,enzymes
R6754 T8114 T8117 nsubj enzymes,cut
R6755 T8115 T8117 aux do,cut
R6756 T8116 T8117 neg not,cut
R6757 T8117 T8117 ROOT cut,cut
R6758 T8118 T8119 amod specific,sites
R6759 T8119 T8117 dobj sites,cut
R6760 T8120 T8119 prep in,sites
R6761 T8121 T8123 det the,promoter
R6762 T8122 T8123 compound IRF-4,promoter
R6763 T8123 T8120 pobj promoter,in
R6764 T8124 T8123 prep in,promoter
R6765 T8125 T8126 amod hematopoietic,cells
R6766 T8126 T8124 pobj cells,in
R6767 T8127 T8129 aux To,investigate
R6768 T8128 T8129 advmod further,investigate
R6769 T8129 T8117 conj investigate,cut
R6770 T8130 T8131 compound promoter,methylation
R6771 T8131 T8129 dobj methylation,investigate
R6772 T8132 T8129 prep as,investigate
R6773 T8133 T8135 det a,mechanism
R6774 T8134 T8135 amod regulatory,mechanism
R6775 T8135 T8132 pobj mechanism,as
R6776 T8136 T8135 prep of,mechanism
R6777 T8137 T8139 compound IRF-4,expression
R6778 T8138 T8139 compound gene,expression
R6779 T8139 T8136 pobj expression,of
R6780 T8140 T8143 punct ",",performed
R6781 T8141 T8143 nsubjpass restriction-PCR-assays,performed
R6782 T8142 T8143 auxpass were,performed
R6783 T8143 T8117 conj performed,cut
R6784 T8144 T8143 punct (,performed
R6785 T8145 T8143 npadvmod "20,24",performed
R6786 T8146 T8143 punct ),performed
R6787 T8147 T8143 punct ",",performed
R6788 T8148 T8155 advmod where,cut
R6789 T8149 T8151 amod only,DNA
R6790 T8150 T8151 amod methylated,DNA
R6791 T8151 T8155 nsubjpass DNA,cut
R6792 T8152 T8155 aux would,cut
R6793 T8153 T8155 neg not,cut
R6794 T8154 T8155 auxpass be,cut
R6795 T8155 T8143 advcl cut,performed
R6796 T8156 T8155 xcomp enabling,cut
R6797 T8157 T8159 amod subsequent,amplification
R6798 T8158 T8159 compound PCR,amplification
R6799 T8159 T8156 dobj amplification,enabling
R6800 T8160 T8159 cc and,amplification
R6801 T8161 T8162 compound vice,versa
R6802 T8162 T8159 conj versa,amplification
R6803 T8163 T8143 punct .,performed
R6804 T8164 T8165 compound Genomic,DNA
R6805 T8165 T8181 nsubjpass DNA,digested
R6806 T8166 T8165 prep from,DNA
R6807 T8167 T8168 amod leukemic,cells
R6808 T8168 T8166 pobj cells,from
R6809 T8169 T8165 conj Jurkat,DNA
R6810 T8170 T8169 punct ",",Jurkat
R6811 T8171 T8169 conj CML-T1,Jurkat
R6812 T8172 T8171 punct ",",CML-T1
R6813 T8173 T8171 conj U-937,CML-T1
R6814 T8174 T8173 punct ",",U-937
R6815 T8175 T8173 conj K-562,U-937
R6816 T8176 T8175 punct ",",K-562
R6817 T8177 T8175 conj EM-2,K-562
R6818 T8178 T8177 cc and,EM-2
R6819 T8179 T8177 conj BV-173,EM-2
R6820 T8180 T8181 auxpass was,digested
R6821 T8181 T8181 ROOT digested,digested
R6822 T8182 T8181 prep with,digested
R6823 T8183 T8185 det the,enzymes
R6824 T8184 T8185 amod methylation-sensitive,enzymes
R6825 T8185 T8182 pobj enzymes,with
R6826 T8186 T8185 appos HpaII,enzymes
R6827 T8187 T8186 punct ",",HpaII
R6828 T8188 T8186 conj Bsh1236I,HpaII
R6829 T8189 T8188 cc and,Bsh1236I
R6830 T8190 T8191 compound HaeII-isochizomer,Bsp143II
R6831 T8191 T8188 conj Bsp143II,Bsh1236I
R6832 T8192 T8181 punct .,digested
R6833 T8193 T8210 nsubj EcoRI,served
R6834 T8194 T8193 punct ",",EcoRI
R6835 T8195 T8196 nsubj which,has
R6836 T8196 T8193 relcl has,EcoRI
R6837 T8197 T8199 det no,site
R6838 T8198 T8199 compound recognition,site
R6839 T8199 T8196 dobj site,has
R6840 T8200 T8199 prep within,site
R6841 T8201 T8203 det the,promoter
R6842 T8202 T8203 compound IRF-4,promoter
R6843 T8203 T8200 pobj promoter,within
R6844 T8204 T8193 punct ",",EcoRI
R6845 T8205 T8193 cc and,EcoRI
R6846 T8206 T8208 det the,enzyme
R6847 T8207 T8208 amod methylation-resistant,enzyme
R6848 T8208 T8210 nsubj enzyme,served
R6849 T8209 T8208 appos MspI,enzyme
R6850 T8210 T8210 ROOT served,served
R6851 T8211 T8210 prep as,served
R6852 T8212 T8211 pobj controls,as
R6853 T8213 T8210 punct .,served
R6854 T8214 T8217 nummod Two,reactions
R6855 T8215 T8217 amod separate,reactions
R6856 T8216 T8217 compound amplification,reactions
R6857 T8217 T8219 nsubjpass reactions,performed
R6858 T8218 T8219 auxpass were,performed
R6859 T8219 T8219 ROOT performed,performed
R6860 T8220 T8219 punct ",",performed
R6861 T8221 T8219 advcl generating,performed
R6862 T8222 T8223 nummod two,fragments
R6863 T8223 T8221 dobj fragments,generating
R6864 T8224 T8223 punct ",",fragments
R6865 T8225 T8223 appos F1,fragments
R6866 T8226 T8225 cc and,F1
R6867 T8227 T8230 compound F2,3A
R6868 T8228 T8229 punct (,Figure
R6869 T8229 T8230 compound Figure,3A
R6870 T8230 T8225 conj 3A,F1
R6871 T8231 T8223 punct ),fragments
R6872 T8232 T8219 punct .,performed
R6873 T8233 T8248 prep After,detected
R6874 T8234 T8233 pobj digestion,After
R6875 T8235 T8234 prep with,digestion
R6876 T8236 T8235 pobj HpaII,with
R6877 T8237 T8236 cc and,HpaII
R6878 T8238 T8236 conj Bsp143II,HpaII
R6879 T8239 T8242 det a,amplification
R6880 T8240 T8242 amod sufficient,amplification
R6881 T8241 T8242 compound PCR,amplification
R6882 T8242 T8248 nsubjpass amplification,detected
R6883 T8243 T8242 prep of,amplification
R6884 T8244 T8243 pobj F1,of
R6885 T8245 T8244 cc and,F1
R6886 T8246 T8244 conj F2,F1
R6887 T8247 T8248 auxpass was,detected
R6888 T8248 T8248 ROOT detected,detected
R6889 T8249 T8248 prep in,detected
R6890 T8250 T8249 pobj DNA,in
R6891 T8251 T8248 prep from,detected
R6892 T8252 T8253 compound IRF-4-negative,Jurkat
R6893 T8253 T8251 pobj Jurkat,from
R6894 T8254 T8253 punct ",",Jurkat
R6895 T8255 T8253 conj CML-T1,Jurkat
R6896 T8256 T8255 punct ",",CML-T1
R6897 T8257 T8255 conj U-937,CML-T1
R6898 T8258 T8257 punct ",",U-937
R6899 T8259 T8257 conj K-562,U-937
R6900 T8260 T8259 cc and,K-562
R6901 T8261 T8259 conj EM-2,K-562
R6902 T8262 T8251 pobj cells,from
R6903 T8263 T8248 punct ",",detected
R6904 T8264 T8248 advcl suggesting,detected
R6905 T8265 T8267 det a,methylation
R6906 T8266 T8267 compound promoter,methylation
R6907 T8267 T8264 dobj methylation,suggesting
R6908 T8268 T8267 punct (,methylation
R6909 T8269 T8267 cc and,methylation
R6910 T8270 T8271 compound restriction,protection
R6911 T8271 T8267 conj protection,methylation
R6912 T8272 T8267 punct ),methylation
R6913 T8273 T8264 prep at,suggesting
R6914 T8274 T8277 det the,sites
R6915 T8275 T8277 amod respective,sites
R6916 T8276 T8277 compound recognition,sites
R6917 T8277 T8273 pobj sites,at
R6918 T8278 T8280 punct (,3B
R6919 T8279 T8280 amod Figure,3B
R6920 T8280 T8277 appos 3B,sites
R6921 T8281 T8280 cc and,3B
R6922 T8282 T8280 conj C,3B
R6923 T8283 T8282 punct ),C
R6924 T8284 T8248 punct .,detected
R6925 T8285 T8297 advmod Notably,inhibited
R6926 T8286 T8297 punct ",",inhibited
R6927 T8287 T8297 prep in,inhibited
R6928 T8288 T8290 amod IRF-4-positive,cells
R6929 T8289 T8290 amod SD-1,cells
R6930 T8290 T8291 compound cells,digestion
R6931 T8291 T8287 pobj digestion,in
R6932 T8292 T8291 prep with,digestion
R6933 T8293 T8295 det the,enzymes
R6934 T8294 T8295 amod methylation-sensitive,enzymes
R6935 T8295 T8292 pobj enzymes,with
R6936 T8296 T8297 advmod completely,inhibited
R6937 T8297 T8297 ROOT inhibited,inhibited
R6938 T8298 T8297 dobj amplification,inhibited
R6939 T8299 T8298 prep of,amplification
R6940 T8300 T8299 pobj F1,of
R6941 T8301 T8300 cc and,F1
R6942 T8302 T8300 conj F2,F1
R6943 T8303 T8297 punct .,inhibited
R6944 T8304 T8318 prep In,reduced
R6945 T8305 T8307 amod IRF-4-positive,cells
R6946 T8306 T8307 amod BV-173,cells
R6947 T8307 T8304 pobj cells,In
R6948 T8308 T8309 det a,HpaII
R6949 T8309 T8318 nsubj HpaII,reduced
R6950 T8310 T8309 punct ",",HpaII
R6951 T8311 T8315 cc but,digestion
R6952 T8312 T8315 neg not,digestion
R6953 T8313 T8315 det a,digestion
R6954 T8314 T8315 amod Bsh1236I,digestion
R6955 T8315 T8309 conj digestion,HpaII
R6956 T8316 T8318 punct ",",reduced
R6957 T8317 T8318 advmod significantly,reduced
R6958 T8318 T8318 ROOT reduced,reduced
R6959 T8319 T8322 det the,message
R6960 T8320 T8322 amod amplifiable,message
R6961 T8321 T8322 compound DNA,message
R6962 T8322 T8318 dobj message,reduced
R6963 T8323 T8322 prep of,message
R6964 T8324 T8323 pobj F2,of
R6965 T8325 T8327 punct (,3C
R6966 T8326 T8327 nmod Figure,3C
R6967 T8327 T8324 appos 3C,F2
R6968 T8328 T8327 punct ),3C
R6969 T8329 T8318 punct ",",reduced
R6970 T8330 T8336 mark whereas,affected
R6971 T8331 T8336 nsubjpass amplification,affected
R6972 T8332 T8331 prep of,amplification
R6973 T8333 T8332 pobj F1,of
R6974 T8334 T8336 auxpass was,affected
R6975 T8335 T8336 neg not,affected
R6976 T8336 T8318 advcl affected,reduced
R6977 T8337 T8339 punct (,3B
R6978 T8338 T8339 compound Figure,3B
R6979 T8339 T8336 npadvmod 3B,affected
R6980 T8340 T8336 punct ),affected
R6981 T8341 T8318 punct .,reduced
R6982 T8342 T8343 nsubj This,implied
R6983 T8343 T8343 ROOT implied,implied
R6984 T8344 T8353 mark that,associated
R6985 T8345 T8346 amod IRF-4,transcription
R6986 T8346 T8353 nsubjpass transcription,associated
R6987 T8347 T8346 prep in,transcription
R6988 T8348 T8347 pobj SD-1,in
R6989 T8349 T8348 cc and,SD-1
R7009 T8369 T8372 det the,cells
R7010 T8370 T8372 amod tested,cells
R7011 T8371 T8372 amod IRF-4-negative,cells
R7012 T8372 T8368 pobj cells,with
R7013 T8373 T8343 punct .,implied
R6990 T8350 T8351 amod BV-173,cells
R6991 T8351 T8348 conj cells,SD-1
R6992 T8352 T8353 auxpass is,associated
R6993 T8353 T8343 ccomp associated,implied
R6994 T8354 T8353 prep with,associated
R6995 T8355 T8356 amod less,promoter
R6996 T8356 T8357 compound promoter,methylation
R6997 T8357 T8354 pobj methylation,with
R6998 T8358 T8357 punct (,methylation
R6999 T8359 T8357 prep in,methylation
R7000 T8360 T8359 pobj BV-173,in
R7001 T8361 T8362 advmod especially,at
R7002 T8362 T8357 prep at,methylation
R7003 T8363 T8364 compound HpaII,sites
R7004 T8364 T8362 pobj sites,at
R7005 T8365 T8353 punct ),associated
R7006 T8366 T8367 mark as,compared
R7007 T8367 T8343 advcl compared,implied
R7008 T8368 T8367 prep with,compared

GO-BP

Id Subject Object Predicate Lexical cue
T7840 0-11 http://purl.obolibrary.org/obo/GO_0032259 denotes Methylation
T7841 133-144 http://purl.obolibrary.org/obo/GO_0032259 denotes methylation
T7842 441-452 http://purl.obolibrary.org/obo/GO_0032259 denotes methylation
T7843 591-602 http://purl.obolibrary.org/obo/GO_0032259 denotes methylation
T7844 938-949 http://purl.obolibrary.org/obo/GO_0032259 denotes methylation
T7845 1091-1102 http://purl.obolibrary.org/obo/GO_0032259 denotes methylation
T7846 1463-1474 http://purl.obolibrary.org/obo/GO_0032259 denotes methylation
T7847 180-195 http://purl.obolibrary.org/obo/GO_0010467 denotes gene expression
T7848 753-762 http://purl.obolibrary.org/obo/GO_0007586 denotes digestion
T7849 1072-1081 http://purl.obolibrary.org/obo/GO_0007586 denotes digestion
T7850 1229-1238 http://purl.obolibrary.org/obo/GO_0007586 denotes digestion
T7851 1391-1404 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription

bionlp-st-ge-2016-reference-tees

Id Subject Object Predicate Lexical cue
T8447 63-77 Protein denotes IRF-4 promoter
T8448 174-184 Protein denotes IRF-4 gene
T8449 185-195 Gene_expression denotes expression
T8450 471-476 Protein denotes HpaII
T8451 478-517 Protein denotes Bsh1236I and HaeII-isochizomer Bsp143II
T8452 519-524 Protein denotes EcoRI
T8453 567-581 Protein denotes IRF-4 promoter
T8454 768-773 Protein denotes HpaII
T8455 778-786 Protein denotes Bsp143II
T8456 753-762 Gene_expression denotes digestion
T8457 753-762 Gene_expression denotes digestion
T8458 1046-1051 Protein denotes IRF-4
T8459 1052-1060 Gene_expression denotes positive
T8460 1203-1208 Protein denotes HpaII
T8461 1385-1390 Protein denotes IRF-4
T8462 1500-1511 Protein denotes HpaII sites
T8463 1391-1404 Transcription denotes transcription
R7038 T8448 T8449 themeOf IRF-4 gene,expression
R7039 T8454 T8456 themeOf HpaII,digestion
R7040 T8455 T8457 themeOf Bsp143II,digestion
R7041 T8458 T8459 themeOf IRF-4,positive
R7042 T8461 T8463 themeOf IRF-4,transcription

bionlp-st-ge-2016-reference

Id Subject Object Predicate Lexical cue Negation
T7817 63-68 Protein denotes IRF-4
T7818 174-179 Protein denotes IRF-4
T7819 185-195 Gene_expression denotes expression
T7820 567-572 Protein denotes IRF-4
T7821 856-861 Protein denotes IRF-4
T7822 862-870 Gene_expression denotes negative true
T7823 1046-1051 Protein denotes IRF-4
T7824 1052-1060 Gene_expression denotes positive
T7825 1173-1178 Protein denotes IRF-4
T7826 1179-1187 Gene_expression denotes positive
T7827 1385-1390 Protein denotes IRF-4
T7828 1391-1404 Transcription denotes transcription
T7829 1541-1546 Protein denotes IRF-4
T7830 1547-1555 Gene_expression denotes negative true
R6491 T7818 T7819 themeOf IRF-4,expression
R6492 T7821 T7822 themeOf IRF-4,negative
R6493 T7823 T7824 themeOf IRF-4,positive
R6494 T7825 T7826 themeOf IRF-4,positive
R6495 T7827 T7828 themeOf IRF-4,transcription
R6496 T7829 T7830 themeOf IRF-4,negative

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T8105 63-68 Q15306 denotes IRF-4
T8106 174-179 Q15306 denotes IRF-4
T8107 567-572 Q15306 denotes IRF-4
T8108 856-861 Q15306 denotes IRF-4
T8109 1046-1051 Q15306 denotes IRF-4
T8110 1173-1178 Q15306 denotes IRF-4
T8111 1385-1390 Q15306 denotes IRF-4
T8112 1541-1546 Q15306 denotes IRF-4

test2

Id Subject Object Predicate Lexical cue Negation
T7803 63-68 Protein denotes IRF-4
T7804 174-179 Protein denotes IRF-4 true
T7805 185-195 Gene_expression denotes expression
T7806 567-572 Protein denotes IRF-4
T7807 856-861 Protein denotes IRF-4
T7808 862-870 Gene_expression denotes negative true
T7809 1046-1051 Protein denotes IRF-4
T7810 1052-1060 Gene_expression denotes positive
T7811 1173-1178 Protein denotes IRF-4
T7812 1179-1187 Gene_expression denotes positive
T7813 1385-1390 Protein denotes IRF-4
T7814 1391-1404 Transcription denotes transcription
T7815 1541-1546 Protein denotes IRF-4
T7816 1547-1555 Gene_expression denotes negative
R6485 T7804 T7805 themeOf IRF-4,expression
R6486 T7807 T7808 themeOf IRF-4,negative
R6487 T7809 T7810 themeOf IRF-4,positive
R6488 T7811 T7812 themeOf IRF-4,positive
R6489 T7813 T7814 themeOf IRF-4,transcription
R6490 T7815 T7816 themeOf IRF-4,negative