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PMC:1310620 / 174-1017 JSONTXT

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Id Subject Object Predicate Lexical cue
T289 0-10 sentence denotes Background
T290 0-10 NN denotes Background
T291 10-207 sentence denotes Cigarette smoking is the primary cause of bronchogenic carcinoma (BC), yet only 10–15% of heavy smokers develop BC and it is likely that this variation in risk is, in part, genetically determined.
T292 11-20 NN denotes Cigarette
T293 21-28 NN denotes smoking
T294 29-31 VBZ denotes is
T295 32-35 DT denotes the
T296 44-49 NN denotes cause
T297 36-43 JJ denotes primary
T298 50-52 IN denotes of
T299 53-65 JJ denotes bronchogenic
T300 66-75 NN denotes carcinoma
T301 76-77 -LRB- denotes (
T302 77-79 NN denotes BC
T303 79-80 -RRB- denotes )
T304 80-82 , denotes ,
T305 82-85 CC denotes yet
T306 86-90 RB denotes only
T307 94-96 CD denotes 15
T308 91-93 CD denotes 10
T309 93-94 SYM denotes –
T310 96-97 NN denotes %
T311 115-122 VBP denotes develop
T312 98-100 IN denotes of
T313 101-106 JJ denotes heavy
T314 107-114 NNS denotes smokers
T315 123-125 NN denotes BC
T316 126-129 CC denotes and
T317 130-132 PRP denotes it
T318 133-135 VBZ denotes is
T319 136-142 JJ denotes likely
T320 143-147 IN denotes that
T321 196-206 VBN denotes determined
T322 148-152 DT denotes this
T323 153-162 NN denotes variation
T324 163-165 IN denotes in
T325 166-170 NN denotes risk
T326 171-173 VBZ denotes is
T327 173-175 , denotes ,
T328 175-177 IN denotes in
T329 178-182 JJ denotes part
T330 182-184 , denotes ,
T331 184-195 RB denotes genetically
T332 206-207 . denotes .
T333 207-392 sentence denotes We previously reported a set of antioxidant genes for which transcript abundance was lower in normal bronchial epithelial cells (NBEC) of BC individuals compared to non-BC individuals.
T334 208-210 PRP denotes We
T335 222-230 VBD denotes reported
T336 211-221 RB denotes previously
T337 231-232 DT denotes a
T338 233-236 NN denotes set
T339 237-239 IN denotes of
T340 240-251 NN denotes antioxidant
T341 252-257 NNS denotes genes
T342 258-261 IN denotes for
T343 289-292 VBD denotes was
T344 262-267 WDT denotes which
T345 268-278 NN denotes transcript
T346 279-288 NN denotes abundance
T347 293-298 JJR denotes lower
T348 299-301 IN denotes in
T349 302-308 JJ denotes normal
T350 330-335 NNS denotes cells
T351 309-318 JJ denotes bronchial
T352 319-329 JJ denotes epithelial
T353 336-337 -LRB- denotes (
T354 337-341 NN denotes NBEC
T355 341-342 -RRB- denotes )
T356 343-345 IN denotes of
T357 346-348 NN denotes BC
T358 349-360 NNS denotes individuals
T359 361-369 VBN denotes compared
T360 370-372 IN denotes to
T361 373-379 JJ denotes non-BC
T362 380-391 NNS denotes individuals
T363 391-392 . denotes .
T364 392-544 sentence denotes In unpublished studies of the same NBEC samples, transcript abundance values for several DNA repair genes were correlated with these antioxidant genes.
T365 393-395 IN denotes In
T366 504-514 VBN denotes correlated
T367 396-407 JJ denotes unpublished
T368 408-415 NNS denotes studies
T369 416-418 IN denotes of
T370 419-422 DT denotes the
T371 433-440 NNS denotes samples
T372 423-427 JJ denotes same
T373 428-432 NN denotes NBEC
T374 440-442 , denotes ,
T375 442-452 NN denotes transcript
T376 463-469 NNS denotes values
T377 453-462 NN denotes abundance
T378 470-473 IN denotes for
T379 474-481 JJ denotes several
T380 493-498 NNS denotes genes
T381 482-485 NN denotes DNA
T382 486-492 NN denotes repair
T383 499-503 VBD denotes were
T384 515-519 IN denotes with
T385 520-525 DT denotes these
T386 538-543 NNS denotes genes
T387 526-537 NN denotes antioxidant
T388 543-544 . denotes .
T389 544-843 sentence denotes From these data, we hypothesized that antioxidant and DNA repair genes are co-regulated by one or more transcription factors and that inter-individual variation in expression and/or function of one or more of these transcription factors is responsible for inter-individual variation in risk for BC.
T390 545-549 IN denotes From
T391 565-577 VBD denotes hypothesized
T392 550-555 DT denotes these
T393 556-560 NNS denotes data
T394 560-562 , denotes ,
T395 562-564 PRP denotes we
T396 578-582 IN denotes that
T397 620-632 VBN denotes co-regulated
T398 583-594 NN denotes antioxidant
T399 610-615 NNS denotes genes
T400 595-598 CC denotes and
T401 599-602 NN denotes DNA
T402 603-609 NN denotes repair
T403 616-619 VBP denotes are
T404 633-635 IN denotes by
T405 636-639 CD denotes one
T406 662-669 NNS denotes factors
T407 640-642 CC denotes or
T408 643-647 JJR denotes more
T409 648-661 NN denotes transcription
T410 670-673 CC denotes and
T411 674-678 IN denotes that
T412 782-784 VBZ denotes is
T413 679-695 JJ denotes inter-individual
T414 696-705 NN denotes variation
T415 706-708 IN denotes in
T416 709-719 NN denotes expression
T417 720-723 CC denotes and
T418 723-724 HYPH denotes /
T419 724-726 CC denotes or
T420 727-735 NN denotes function
T421 736-738 IN denotes of
T422 739-742 CD denotes one
T423 743-745 CC denotes or
T424 746-750 JJR denotes more
T425 751-753 IN denotes of
T426 754-759 DT denotes these
T427 774-781 NNS denotes factors
T428 760-773 NN denotes transcription
T429 785-796 JJ denotes responsible
T430 797-800 IN denotes for
T431 801-817 JJ denotes inter-individual
T432 818-827 NN denotes variation
T433 828-830 IN denotes in
T434 831-835 NN denotes risk
T435 836-839 IN denotes for
T436 840-842 NN denotes BC
T437 842-843 . denotes .
R94 T370 T371 det the,samples
R95 T371 T369 pobj samples,of
R21 T292 T293 compound Cigarette,smoking
R22 T293 T294 nsubj smoking,is
R23 T295 T296 det the,cause
R24 T296 T294 attr cause,is
R26 T298 T296 prep of,cause
R27 T299 T300 amod bronchogenic,carcinoma
R28 T300 T298 pobj carcinoma,of
R29 T301 T300 punct (,carcinoma
R30 T302 T300 appos BC,carcinoma
R31 T303 T294 punct ),is
R32 T304 T294 punct ", ",is
R33 T305 T294 cc yet,is
R34 T306 T307 advmod only,15
R35 T307 T310 nummod 15,%
R38 T310 T311 nsubj %,develop
R39 T311 T294 conj develop,is
R43 T315 T311 dobj BC,develop
R44 T316 T311 cc and,develop
R45 T317 T318 nsubj it,is
R46 T318 T311 conj is,develop
R47 T319 T318 acomp likely,is
R48 T320 T321 mark that,determined
R49 T321 T318 ccomp determined,is
R60 T332 T311 punct .,develop
R61 T334 T335 nsubj We,reported
R62 T336 T335 advmod previously,reported
R63 T337 T338 det a,set
R64 T338 T335 dobj set,reported
R65 T339 T338 prep of,set
R66 T340 T341 compound antioxidant,genes
R67 T341 T339 pobj genes,of
R68 T342 T343 prep for,was
R69 T343 T341 relcl was,genes
R73 T347 T343 acomp lower,was
R74 T348 T343 prep in,was
R75 T349 T350 amod normal,cells
R76 T350 T348 pobj cells,in
R79 T353 T350 punct (,cells
R80 T354 T350 appos NBEC,cells
R81 T355 T350 punct ),cells
R82 T356 T350 prep of,cells
R83 T357 T358 compound BC,individuals
R84 T358 T356 pobj individuals,of
R85 T359 T343 prep compared,was
R86 T360 T359 prep to,compared
R87 T361 T362 amod non-BC,individuals
R88 T362 T360 pobj individuals,to
R89 T363 T335 punct .,reported
R90 T365 T366 prep In,correlated
R91 T367 T368 amod unpublished,studies
R92 T368 T365 pobj studies,In
R93 T369 T368 prep of,studies
R98 T374 T366 punct ", ",correlated
R99 T375 T376 compound transcript,values
R100 T376 T366 nsubjpass values,correlated
R102 T378 T376 prep for,values
R103 T379 T380 amod several,genes
R104 T380 T378 pobj genes,for
R107 T383 T366 auxpass were,correlated
R108 T384 T366 prep with,correlated
R109 T385 T386 det these,genes
R110 T386 T384 pobj genes,with
R112 T388 T366 punct .,correlated
R113 T390 T391 prep From,hypothesized
R114 T392 T393 det these,data
R115 T393 T390 pobj data,From
R116 T394 T391 punct ", ",hypothesized
R117 T395 T391 nsubj we,hypothesized
R118 T396 T397 mark that,co-regulated
R119 T397 T391 advcl co-regulated,hypothesized
R121 T399 T397 nsubjpass genes,co-regulated
R122 T400 T398 cc and,antioxidant
R123 T401 T402 compound DNA,repair
R124 T402 T398 conj repair,antioxidant
R126 T404 T397 agent by,co-regulated
R127 T405 T406 nummod one,factors
R128 T406 T404 pobj factors,by
R132 T410 T397 cc and,co-regulated
R133 T411 T412 mark that,is
R134 T412 T397 conj is,co-regulated
R149 T427 T425 pobj factors,of
R150 T428 T427 compound transcription,factors
R151 T429 T412 acomp responsible,is
R152 T430 T429 prep for,responsible
R153 T431 T432 amod inter-individual,variation
R154 T432 T430 pobj variation,for
R155 T433 T432 prep in,variation
R156 T434 T433 pobj risk,in
R157 T435 T434 prep for,risk
R158 T436 T435 pobj BC,for
R159 T437 T391 punct .,hypothesized
R25 T297 T296 amod primary,cause
R36 T308 T307 quantmod 10,15
R37 T309 T307 punct –,15
R40 T312 T310 prep of,%
R41 T313 T314 amod heavy,smokers
R42 T314 T312 pobj smokers,of
R50 T322 T323 det this,variation
R51 T323 T321 nsubjpass variation,determined
R52 T324 T323 prep in,variation
R53 T325 T324 pobj risk,in
R54 T326 T321 auxpass is,determined
R55 T327 T321 punct ", ",determined
R56 T328 T321 prep in,determined
R57 T329 T328 amod part,in
R58 T330 T321 punct ", ",determined
R59 T331 T321 advmod genetically,determined
R70 T344 T342 pobj which,for
R71 T345 T346 compound transcript,abundance
R72 T346 T343 nsubj abundance,was
R77 T351 T350 amod bronchial,cells
R78 T352 T350 amod epithelial,cells
R96 T372 T371 amod same,samples
R97 T373 T371 compound NBEC,samples
R101 T377 T376 compound abundance,values
R105 T381 T382 compound DNA,repair
R106 T382 T380 compound repair,genes
R111 T387 T386 compound antioxidant,genes
R120 T398 T399 nmod antioxidant,genes
R125 T403 T397 auxpass are,co-regulated
R129 T407 T405 cc or,one
R130 T408 T405 conj more,one
R131 T409 T406 compound transcription,factors
R135 T413 T414 amod inter-individual,variation
R136 T414 T412 nsubj variation,is
R137 T415 T414 prep in,variation
R138 T416 T415 pobj expression,in
R139 T417 T416 cc and,expression
R140 T418 T417 punct /,and
R141 T419 T417 cc or,and
R142 T420 T416 conj function,expression
R143 T421 T416 prep of,expression
R144 T422 T421 pobj one,of
R145 T423 T422 cc or,one
R146 T424 T422 conj more,one
R147 T425 T422 prep of,one
R148 T426 T427 det these,factors

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T109 184-195 SO_EXT:0000704 denotes genetically
T110 240-251 CHEBI_GO_EXT:antioxidant denotes antioxidant
T111 244-251 CHEBI_MOP_EXT:oxidising_agent_or_oxidation denotes oxidant
T112 252-257 SO_EXT:0000704 denotes genes
T113 268-278 SO_EXT:0000673 denotes transcript
T114 309-329 UBERON:0002031 denotes bronchial epithelial
T115 309-335 CL:0002328 denotes bronchial epithelial cells
T116 330-335 CL_GO_EXT:cell denotes cells
T117 349-360 NCBITaxon:1 denotes individuals
T118 380-391 NCBITaxon:1 denotes individuals
T119 442-452 SO_EXT:0000673 denotes transcript
T120 482-485 CHEBI_SO_EXT:DNA denotes DNA
T121 482-492 GO:0006281 denotes DNA repair
T122 493-498 SO_EXT:0000704 denotes genes
T123 526-537 CHEBI_GO_EXT:antioxidant denotes antioxidant
T124 530-537 CHEBI_MOP_EXT:oxidising_agent_or_oxidation denotes oxidant
T125 538-543 SO_EXT:0000704 denotes genes
T126 583-594 CHEBI_GO_EXT:antioxidant denotes antioxidant
T127 587-594 CHEBI_MOP_EXT:oxidising_agent_or_oxidation denotes oxidant
T128 599-602 CHEBI_SO_EXT:DNA denotes DNA
T129 599-609 GO:0006281 denotes DNA repair
T130 610-615 SO_EXT:0000704 denotes genes
T131 623-632 GO:0065007 denotes regulated
T132 648-661 GO_EXT:transcription denotes transcription
T133 648-669 GO_EXT:transcription_factor denotes transcription factors
T134 685-695 NCBITaxon:1 denotes individual
T135 709-719 GO:0010467 denotes expression
T136 760-773 GO_EXT:transcription denotes transcription
T137 760-781 GO_EXT:transcription_factor denotes transcription factors
T138 807-817 NCBITaxon:1 denotes individual

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T210 184-195 SO:0000704 denotes genetically
T211 252-257 SO:0000704 denotes genes
T212 268-278 SO:0000673 denotes transcript
T213 309-329 UBERON:0002031 denotes bronchial epithelial
T214 309-335 CL:0002328 denotes bronchial epithelial cells
T215 349-360 NCBITaxon:1 denotes individuals
T216 380-391 NCBITaxon:1 denotes individuals
T217 442-452 SO:0000673 denotes transcript
T218 482-492 GO:0006281 denotes DNA repair
T219 493-498 SO:0000704 denotes genes
T220 538-543 SO:0000704 denotes genes
T221 599-609 GO:0006281 denotes DNA repair
T222 610-615 SO:0000704 denotes genes
T223 623-632 GO:0065007 denotes regulated
T224 685-695 NCBITaxon:1 denotes individual
T225 709-719 GO:0010467 denotes expression
T226 807-817 NCBITaxon:1 denotes individual