PMC:1285065 / 1432-2347 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/1285065","sourcedb":"PMC","sourceid":"1285065","source_url":"http://www.ncbi.nlm.nih.gov/pmc/1285065","text":"Synopsis\nOne of the more intriguing mysteries in chromosome biology lies in the ability of homologous chromosomes to pair during meiosis, the process that creates haploid gametes. This pairing is the crucial first step in seeing to it that each gamete receives one, and only one, copy of each chromosome. The later steps in this process include recombination and the actual segregation of paired homologs into different daughter cells. During the last century of study, people who worked on meiosis believed that changes in chromosome structure that disrupted the meiotic processes did so by impeding the pairing process. Here the authors show that pairing occurs quite normally even in cells carrying a highly rearranged chromosome. Surprisingly, even recombination is normally initiated, but not completed. These data are allowing them to reconsider several old and cherished views of the process called meiosis.\n","divisions":[{"label":"Title","span":{"begin":0,"end":8}}],"tracks":[]}