PMC:1283364 / 4506-4723 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1283364","sourcedb":"PMC","sourceid":"1283364","source_url":"http://www.ncbi.nlm.nih.gov/pmc/1283364","text":"ether the brain can clear pre-existing amyloid deposits once production of Aβ has been suppressed.\nClearly, the amyloid-lowering approach should be rigorously examined in animal models before these reagents are tested","tracks":[{"project":"craft-sa-dev","denotations":[{"id":"T1155","span":{"begin":20,"end":25},"obj":"VB"},{"id":"T1156","span":{"begin":6,"end":9},"obj":"DT"},{"id":"T1157","span":{"begin":10,"end":15},"obj":"NN"},{"id":"T1158","span":{"begin":16,"end":19},"obj":"MD"},{"id":"T1159","span":{"begin":26,"end":38},"obj":"JJ"},{"id":"T1160","span":{"begin":47,"end":55},"obj":"NNS"},{"id":"T1161","span":{"begin":39,"end":46},"obj":"NN"},{"id":"T1162","span":{"begin":56,"end":60},"obj":"IN"},{"id":"T1163","span":{"begin":87,"end":97},"obj":"VBN"},{"id":"T1164","span":{"begin":61,"end":71},"obj":"NN"},{"id":"T1165","span":{"begin":72,"end":74},"obj":"IN"},{"id":"T1166","span":{"begin":75,"end":77},"obj":"NN"},{"id":"T1167","span":{"begin":78,"end":81},"obj":"VBZ"},{"id":"T1168","span":{"begin":82,"end":86},"obj":"VBN"},{"id":"T1169","span":{"begin":97,"end":98},"obj":"."},{"id":"T1171","span":{"begin":99,"end":106},"obj":"RB"},{"id":"T1172","span":{"begin":159,"end":167},"obj":"VBN"},{"id":"T1173","span":{"begin":106,"end":108},"obj":","},{"id":"T1174","span":{"begin":108,"end":111},"obj":"DT"},{"id":"T1175","span":{"begin":129,"end":137},"obj":"NN"},{"id":"T1176","span":{"begin":112,"end":119},"obj":"NN"},{"id":"T1177","span":{"begin":120,"end":128},"obj":"VBG"},{"id":"T1178","span":{"begin":119,"end":120},"obj":"HYPH"},{"id":"T1179","span":{"begin":138,"end":144},"obj":"MD"},{"id":"T1180","span":{"begin":145,"end":147},"obj":"VB"},{"id":"T1181","span":{"begin":148,"end":158},"obj":"RB"},{"id":"T1182","span":{"begin":168,"end":170},"obj":"IN"},{"id":"T1183","span":{"begin":171,"end":177},"obj":"NN"},{"id":"T1184","span":{"begin":178,"end":184},"obj":"NNS"},{"id":"T1185","span":{"begin":185,"end":191},"obj":"IN"},{"id":"T1186","span":{"begin":211,"end":217},"obj":"VBN"},{"id":"T1187","span":{"begin":192,"end":197},"obj":"DT"},{"id":"T1188","span":{"begin":198,"end":206},"obj":"NNS"},{"id":"T1189","span":{"begin":207,"end":210},"obj":"VBP"}],"relations":[{"id":"R752","pred":"det","subj":"T1156","obj":"T1157"},{"id":"R753","pred":"nsubj","subj":"T1157","obj":"T1155"},{"id":"R754","pred":"aux","subj":"T1158","obj":"T1155"},{"id":"R755","pred":"amod","subj":"T1159","obj":"T1160"},{"id":"R756","pred":"dobj","subj":"T1160","obj":"T1155"},{"id":"R757","pred":"compound","subj":"T1161","obj":"T1160"},{"id":"R758","pred":"mark","subj":"T1162","obj":"T1163"},{"id":"R759","pred":"advcl","subj":"T1163","obj":"T1155"},{"id":"R760","pred":"nsubjpass","subj":"T1164","obj":"T1163"},{"id":"R761","pred":"prep","subj":"T1165","obj":"T1164"},{"id":"R762","pred":"pobj","subj":"T1166","obj":"T1165"},{"id":"R763","pred":"aux","subj":"T1167","obj":"T1163"},{"id":"R764","pred":"auxpass","subj":"T1168","obj":"T1163"},{"id":"R766","pred":"advmod","subj":"T1171","obj":"T1172"},{"id":"R767","pred":"punct","subj":"T1173","obj":"T1172"},{"id":"R768","pred":"det","subj":"T1174","obj":"T1175"},{"id":"R769","pred":"nsubjpass","subj":"T1175","obj":"T1172"},{"id":"R770","pred":"npadvmod","subj":"T1176","obj":"T1177"},{"id":"R771","pred":"amod","subj":"T1177","obj":"T1175"},{"id":"R772","pred":"punct","subj":"T1178","obj":"T1177"},{"id":"R773","pred":"aux","subj":"T1179","obj":"T1172"},{"id":"R774","pred":"auxpass","subj":"T1180","obj":"T1172"},{"id":"R775","pred":"advmod","subj":"T1181","obj":"T1172"},{"id":"R776","pred":"prep","subj":"T1182","obj":"T1172"},{"id":"R777","pred":"compound","subj":"T1183","obj":"T1184"},{"id":"R778","pred":"pobj","subj":"T1184","obj":"T1182"},{"id":"R779","pred":"mark","subj":"T1185","obj":"T1186"},{"id":"R780","pred":"advcl","subj":"T1186","obj":"T1172"},{"id":"R781","pred":"det","subj":"T1187","obj":"T1188"},{"id":"R782","pred":"nsubjpass","subj":"T1188","obj":"T1186"},{"id":"R783","pred":"auxpass","subj":"T1189","obj":"T1186"}],"attributes":[{"subj":"T1155","pred":"source","obj":"craft-sa-dev"},{"subj":"T1156","pred":"source","obj":"craft-sa-dev"},{"subj":"T1157","pred":"source","obj":"craft-sa-dev"},{"subj":"T1158","pred":"source","obj":"craft-sa-dev"},{"subj":"T1159","pred":"source","obj":"craft-sa-dev"},{"subj":"T1160","pred":"source","obj":"craft-sa-dev"},{"subj":"T1161","pred":"source","obj":"craft-sa-dev"},{"subj":"T1162","pred":"source","obj":"craft-sa-dev"},{"subj":"T1163","pred":"source","obj":"craft-sa-dev"},{"subj":"T1164","pred":"source","obj":"craft-sa-dev"},{"subj":"T1165","pred":"source","obj":"craft-sa-dev"},{"subj":"T1166","pred":"source","obj":"craft-sa-dev"},{"subj":"T1167","pred":"source","obj":"craft-sa-dev"},{"subj":"T1168","pred":"source","obj":"craft-sa-dev"},{"subj":"T1169","pred":"source","obj":"craft-sa-dev"},{"subj":"T1171","pred":"source","obj":"craft-sa-dev"},{"subj":"T1172","pred":"source","obj":"craft-sa-dev"},{"subj":"T1173","pred":"source","obj":"craft-sa-dev"},{"subj":"T1174","pred":"source","obj":"craft-sa-dev"},{"subj":"T1175","pred":"source","obj":"craft-sa-dev"},{"subj":"T1176","pred":"source","obj":"craft-sa-dev"},{"subj":"T1177","pred":"source","obj":"craft-sa-dev"},{"subj":"T1178","pred":"source","obj":"craft-sa-dev"},{"subj":"T1179","pred":"source","obj":"craft-sa-dev"},{"subj":"T1180","pred":"source","obj":"craft-sa-dev"},{"subj":"T1181","pred":"source","obj":"craft-sa-dev"},{"subj":"T1182","pred":"source","obj":"craft-sa-dev"},{"subj":"T1183","pred":"source","obj":"craft-sa-dev"},{"subj":"T1184","pred":"source","obj":"craft-sa-dev"},{"subj":"T1185","pred":"source","obj":"craft-sa-dev"},{"subj":"T1186","pred":"source","obj":"craft-sa-dev"},{"subj":"T1187","pred":"source","obj":"craft-sa-dev"},{"subj":"T1188","pred":"source","obj":"craft-sa-dev"},{"subj":"T1189","pred":"source","obj":"craft-sa-dev"}]},{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T677","span":{"begin":10,"end":15},"obj":"UBERON:0000955"},{"id":"T678","span":{"begin":39,"end":46},"obj":"CHEBI:60425"},{"id":"T679","span":{"begin":61,"end":77},"obj":"GO:0034205"},{"id":"T680","span":{"begin":75,"end":77},"obj":"CHEBI_PR_EXT:amyloid_beta"},{"id":"T681","span":{"begin":112,"end":119},"obj":"CHEBI:60425"},{"id":"T682","span":{"begin":171,"end":177},"obj":"NCBITaxon:33208"},{"id":"T683","span":{"begin":198,"end":206},"obj":"CHEBI_EXT:33893"}],"attributes":[{"subj":"T677","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T678","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T679","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T680","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T681","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T682","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T683","pred":"source","obj":"craft-ca-core-ex-dev"}]},{"project":"craft-ca-core-dev","denotations":[{"id":"T585","span":{"begin":10,"end":15},"obj":"UBERON:0000955"},{"id":"T586","span":{"begin":39,"end":46},"obj":"CHEBI:60425"},{"id":"T587","span":{"begin":61,"end":77},"obj":"GO:0034205"},{"id":"T588","span":{"begin":112,"end":119},"obj":"CHEBI:60425"},{"id":"T589","span":{"begin":171,"end":177},"obj":"NCBITaxon:33208"},{"id":"T590","span":{"begin":198,"end":206},"obj":"CHEBI:33893"}],"attributes":[{"subj":"T585","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T586","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T587","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T588","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T589","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T590","pred":"source","obj":"craft-ca-core-dev"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"craft-sa-dev","color":"#c093ec","default":true},{"id":"craft-ca-core-ex-dev","color":"#93eca6"},{"id":"craft-ca-core-dev","color":"#ec9399"}]}]}}