Id |
Subject |
Object |
Predicate |
Lexical cue |
T8806 |
0-2 |
PRP |
denotes |
We |
T8807 |
8-12 |
VBD |
denotes |
used |
T8808 |
3-7 |
RB |
denotes |
next |
T8809 |
13-18 |
NN |
denotes |
ELISA |
T8810 |
19-21 |
TO |
denotes |
to |
T8811 |
22-29 |
VB |
denotes |
measure |
T8812 |
30-35 |
JJ |
denotes |
total |
T8813 |
36-38 |
NN |
denotes |
Aβ |
T8814 |
39-41 |
IN |
denotes |
in |
T8815 |
42-45 |
DT |
denotes |
the |
T8816 |
46-52 |
NNS |
denotes |
brains |
T8817 |
53-55 |
IN |
denotes |
of |
T8818 |
56-60 |
DT |
denotes |
each |
T8819 |
61-66 |
NN |
denotes |
group |
T8820 |
67-69 |
TO |
denotes |
to |
T8821 |
70-79 |
VB |
denotes |
determine |
T8822 |
80-87 |
IN |
denotes |
whether |
T8823 |
138-146 |
VBD |
denotes |
occurred |
T8824 |
88-91 |
DT |
denotes |
any |
T8825 |
92-98 |
NN |
denotes |
change |
T8826 |
99-101 |
IN |
denotes |
in |
T8827 |
102-105 |
DT |
denotes |
the |
T8828 |
106-112 |
NN |
denotes |
amount |
T8829 |
113-115 |
CC |
denotes |
or |
T8830 |
116-126 |
NN |
denotes |
solubility |
T8831 |
127-129 |
IN |
denotes |
of |
T8832 |
130-137 |
NN |
denotes |
peptide |
T8833 |
147-152 |
IN |
denotes |
while |
T8834 |
179-189 |
VBN |
denotes |
suppressed |
T8835 |
153-159 |
NN |
denotes |
APPswe |
T8836 |
160-163 |
NN |
denotes |
ind |
T8837 |
159-160 |
HYPH |
denotes |
/ |
T8838 |
164-174 |
NN |
denotes |
expression |
T8839 |
175-178 |
VBD |
denotes |
was |
T8840 |
189-190 |
. |
denotes |
. |
T8841 |
190-383 |
sentence |
denotes |
Cortical homogenates were sequentially extracted to separate peptide into PBS-, SDS-, and FA-soluble fractions, then transgene-derived Aβ40 and Aβ42 were measured by human-specific ELISA [23]. |
T8842 |
191-199 |
JJ |
denotes |
Cortical |
T8843 |
200-211 |
NNS |
denotes |
homogenates |
T8844 |
230-239 |
VBN |
denotes |
extracted |
T8845 |
212-216 |
VBD |
denotes |
were |
T8846 |
217-229 |
RB |
denotes |
sequentially |
T8847 |
345-353 |
VBN |
denotes |
measured |
T8848 |
240-242 |
TO |
denotes |
to |
T8849 |
243-251 |
VB |
denotes |
separate |
T8850 |
252-259 |
NN |
denotes |
peptide |
T8851 |
260-264 |
IN |
denotes |
into |
T8852 |
265-268 |
NN |
denotes |
PBS |
T8853 |
284-291 |
JJ |
denotes |
soluble |
T8854 |
268-269 |
HYPH |
denotes |
- |
T8855 |
269-271 |
, |
denotes |
, |
T8856 |
271-274 |
NN |
denotes |
SDS |
T8857 |
274-275 |
HYPH |
denotes |
- |
T8858 |
275-277 |
, |
denotes |
, |
T8859 |
277-280 |
CC |
denotes |
and |
T8860 |
281-283 |
NN |
denotes |
FA |
T8861 |
283-284 |
HYPH |
denotes |
- |
T8862 |
292-301 |
NNS |
denotes |
fractions |
T8863 |
301-303 |
, |
denotes |
, |
T8864 |
303-307 |
RB |
denotes |
then |
T8865 |
308-317 |
NN |
denotes |
transgene |
T8866 |
318-325 |
VBN |
denotes |
derived |
T8867 |
317-318 |
HYPH |
denotes |
- |
T8868 |
326-330 |
NN |
denotes |
Aβ40 |
T8869 |
331-334 |
CC |
denotes |
and |
T8870 |
335-339 |
NN |
denotes |
Aβ42 |
T8871 |
340-344 |
VBD |
denotes |
were |
T8872 |
354-356 |
IN |
denotes |
by |
T8873 |
357-362 |
JJ |
denotes |
human |
T8874 |
363-371 |
JJ |
denotes |
specific |
T8875 |
362-363 |
HYPH |
denotes |
- |
T8876 |
372-377 |
NN |
denotes |
ELISA |
T8877 |
378-379 |
-LRB- |
denotes |
[ |
T8878 |
379-381 |
CD |
denotes |
23 |
T8879 |
381-382 |
-RRB- |
denotes |
] |
T8880 |
382-383 |
. |
denotes |
. |
T8881 |
383-535 |
sentence |
denotes |
In all animals harboring amyloid deposits, we found that the vast majority of Aβ (>99%) was extracted into the SDS and FA fractions (Figure 5A and 5B). |
T8882 |
384-386 |
IN |
denotes |
In |
T8883 |
430-435 |
VBD |
denotes |
found |
T8884 |
387-390 |
DT |
denotes |
all |
T8885 |
391-398 |
NNS |
denotes |
animals |
T8886 |
399-408 |
VBG |
denotes |
harboring |
T8887 |
409-416 |
NN |
denotes |
amyloid |
T8888 |
417-425 |
NNS |
denotes |
deposits |
T8889 |
425-427 |
, |
denotes |
, |
T8890 |
427-429 |
PRP |
denotes |
we |
T8891 |
436-440 |
IN |
denotes |
that |
T8892 |
476-485 |
VBN |
denotes |
extracted |
T8893 |
441-444 |
DT |
denotes |
the |
T8894 |
450-458 |
NN |
denotes |
majority |
T8895 |
445-449 |
JJ |
denotes |
vast |
T8896 |
459-461 |
IN |
denotes |
of |
T8897 |
462-464 |
NN |
denotes |
Aβ |
T8898 |
465-466 |
-LRB- |
denotes |
( |
T8899 |
469-470 |
NN |
denotes |
% |
T8900 |
466-467 |
SYM |
denotes |
> |
T8901 |
467-469 |
CD |
denotes |
99 |
T8902 |
470-471 |
-RRB- |
denotes |
) |
T8903 |
472-475 |
VBD |
denotes |
was |
T8904 |
486-490 |
IN |
denotes |
into |
T8905 |
491-494 |
DT |
denotes |
the |
T8906 |
506-515 |
NNS |
denotes |
fractions |
T8907 |
495-498 |
NN |
denotes |
SDS |
T8908 |
499-502 |
CC |
denotes |
and |
T8909 |
503-505 |
NN |
denotes |
FA |
T8910 |
516-517 |
-LRB- |
denotes |
( |
T8911 |
524-526 |
NN |
denotes |
5A |
T8912 |
517-523 |
NN |
denotes |
Figure |
T8913 |
527-530 |
CC |
denotes |
and |
T8914 |
531-533 |
NN |
denotes |
5B |
T8915 |
533-534 |
-RRB- |
denotes |
) |
T8916 |
534-535 |
. |
denotes |
. |
T8917 |
535-756 |
sentence |
denotes |
Consistent with the filter trap results presented above, there were no significant differences in SDS- or FA-soluble Aβ between the 6 mo untreated cohort and either the 6 mo + 3 mo treated or 6 mo + 6 mo treated cohorts. |
T8918 |
536-546 |
JJ |
denotes |
Consistent |
T8919 |
599-603 |
VBD |
denotes |
were |
T8920 |
547-551 |
IN |
denotes |
with |
T8921 |
552-555 |
DT |
denotes |
the |
T8922 |
568-575 |
NNS |
denotes |
results |
T8923 |
556-562 |
NN |
denotes |
filter |
T8924 |
563-567 |
NN |
denotes |
trap |
T8925 |
576-585 |
VBN |
denotes |
presented |
T8926 |
586-591 |
RB |
denotes |
above |
T8927 |
591-593 |
, |
denotes |
, |
T8928 |
593-598 |
EX |
denotes |
there |
T8929 |
604-606 |
DT |
denotes |
no |
T8930 |
619-630 |
NNS |
denotes |
differences |
T8931 |
607-618 |
JJ |
denotes |
significant |
T8932 |
631-633 |
IN |
denotes |
in |
T8933 |
634-637 |
NN |
denotes |
SDS |
T8934 |
645-652 |
JJ |
denotes |
soluble |
T8935 |
637-638 |
HYPH |
denotes |
- |
T8936 |
639-641 |
CC |
denotes |
or |
T8937 |
642-644 |
NN |
denotes |
FA |
T8938 |
644-645 |
HYPH |
denotes |
- |
T8939 |
653-655 |
NN |
denotes |
Aβ |
T8940 |
656-663 |
IN |
denotes |
between |
T8941 |
664-667 |
DT |
denotes |
the |
T8942 |
683-689 |
NN |
denotes |
cohort |
T8943 |
668-669 |
CD |
denotes |
6 |
T8944 |
670-672 |
NN |
denotes |
mo |
T8945 |
673-682 |
JJ |
denotes |
untreated |
T8946 |
690-693 |
CC |
denotes |
and |
T8947 |
694-700 |
CC |
denotes |
either |
T8948 |
748-755 |
NNS |
denotes |
cohorts |
T8949 |
701-704 |
DT |
denotes |
the |
T8950 |
705-706 |
CD |
denotes |
6 |
T8951 |
707-709 |
NN |
denotes |
mo |
T8952 |
710-711 |
SYM |
denotes |
+ |
T8953 |
712-713 |
CD |
denotes |
3 |
T8954 |
714-716 |
NN |
denotes |
mo |
T8955 |
717-724 |
VBN |
denotes |
treated |
T8956 |
725-727 |
CC |
denotes |
or |
T8957 |
728-729 |
CD |
denotes |
6 |
T8958 |
730-732 |
NN |
denotes |
mo |
T8959 |
733-734 |
SYM |
denotes |
+ |
T8960 |
735-736 |
CD |
denotes |
6 |
T8961 |
737-739 |
NN |
denotes |
mo |
T8962 |
740-747 |
VBN |
denotes |
treated |
T8963 |
755-756 |
. |
denotes |
. |
T8964 |
756-913 |
sentence |
denotes |
However, brains of both 6 mo + 3 mo and 6 mo + 6 mo treated cohorts contained roughly twice as much PBS-soluble Aβ40 as untreated 6-mo-old mice (Figure 5C). |
T8965 |
757-764 |
RB |
denotes |
However |
T8966 |
825-834 |
VBD |
denotes |
contained |
T8967 |
764-766 |
, |
denotes |
, |
T8968 |
766-772 |
NNS |
denotes |
brains |
T8969 |
773-775 |
IN |
denotes |
of |
T8970 |
776-780 |
CC |
denotes |
both |
T8971 |
783-785 |
NN |
denotes |
mo |
T8972 |
781-782 |
CD |
denotes |
6 |
T8973 |
809-816 |
VBN |
denotes |
treated |
T8974 |
786-787 |
SYM |
denotes |
+ |
T8975 |
788-789 |
CD |
denotes |
3 |
T8976 |
790-792 |
NN |
denotes |
mo |
T8977 |
793-796 |
CC |
denotes |
and |
T8978 |
797-798 |
CD |
denotes |
6 |
T8979 |
799-801 |
NN |
denotes |
mo |
T8980 |
802-803 |
SYM |
denotes |
+ |
T8981 |
804-805 |
CD |
denotes |
6 |
T8982 |
806-808 |
NN |
denotes |
mo |
T8983 |
817-824 |
NNS |
denotes |
cohorts |
T8984 |
835-842 |
RB |
denotes |
roughly |
T8985 |
843-848 |
RB |
denotes |
twice |
T8986 |
852-856 |
JJ |
denotes |
much |
T8987 |
849-851 |
RB |
denotes |
as |
T8988 |
869-873 |
NN |
denotes |
Aβ40 |
T8989 |
857-860 |
NN |
denotes |
PBS |
T8990 |
860-861 |
HYPH |
denotes |
- |
T8991 |
861-868 |
JJ |
denotes |
soluble |
T8992 |
874-876 |
IN |
denotes |
as |
T8993 |
877-886 |
JJ |
denotes |
untreated |
T8994 |
896-900 |
NNS |
denotes |
mice |
T8995 |
887-888 |
CD |
denotes |
6 |
T8996 |
889-891 |
NN |
denotes |
mo |
T8997 |
888-889 |
HYPH |
denotes |
- |
T8998 |
892-895 |
JJ |
denotes |
old |
T8999 |
891-892 |
HYPH |
denotes |
- |
T9000 |
901-902 |
-LRB- |
denotes |
( |
T9001 |
909-911 |
NN |
denotes |
5C |
T9002 |
902-908 |
NN |
denotes |
Figure |
T9003 |
911-912 |
-RRB- |
denotes |
) |
T9004 |
912-913 |
. |
denotes |
. |
T9005 |
913-996 |
sentence |
denotes |
Levels of Aβ42 showed a similar trend, but did not reach statistical significance. |
T9006 |
914-920 |
NNS |
denotes |
Levels |
T9007 |
929-935 |
VBD |
denotes |
showed |
T9008 |
921-923 |
IN |
denotes |
of |
T9009 |
924-928 |
NN |
denotes |
Aβ42 |
T9010 |
936-937 |
DT |
denotes |
a |
T9011 |
946-951 |
NN |
denotes |
trend |
T9012 |
938-945 |
JJ |
denotes |
similar |
T9013 |
951-953 |
, |
denotes |
, |
T9014 |
953-956 |
CC |
denotes |
but |
T9015 |
957-960 |
VBD |
denotes |
did |
T9016 |
965-970 |
VB |
denotes |
reach |
T9017 |
961-964 |
RB |
denotes |
not |
T9018 |
971-982 |
JJ |
denotes |
statistical |
T9019 |
983-995 |
NN |
denotes |
significance |
T9020 |
995-996 |
. |
denotes |
. |
T9021 |
996-1313 |
sentence |
denotes |
In fact, levels of PBS-soluble Aβ40 and Aβ42 in the 6 mo + 3 mo and 6 mo + 6 mo treated cohorts were most similar to that of the 9 mo untreated cohort, suggesting that age, as opposed to synthetic rate (which would be negligible in the treated animals), may determine the fraction of PBS-soluble Aβ in these animals. |
T9022 |
997-999 |
IN |
denotes |
In |
T9023 |
1093-1097 |
VBD |
denotes |
were |
T9024 |
1000-1004 |
NN |
denotes |
fact |
T9025 |
1004-1006 |
, |
denotes |
, |
T9026 |
1006-1012 |
NNS |
denotes |
levels |
T9027 |
1013-1015 |
IN |
denotes |
of |
T9028 |
1016-1019 |
NN |
denotes |
PBS |
T9029 |
1020-1027 |
JJ |
denotes |
soluble |
T9030 |
1019-1020 |
HYPH |
denotes |
- |
T9031 |
1028-1032 |
NN |
denotes |
Aβ40 |
T9032 |
1033-1036 |
CC |
denotes |
and |
T9033 |
1037-1041 |
NN |
denotes |
Aβ42 |
T9034 |
1042-1044 |
IN |
denotes |
in |
T9035 |
1045-1048 |
DT |
denotes |
the |
T9036 |
1085-1092 |
NNS |
denotes |
cohorts |
T9037 |
1049-1050 |
CD |
denotes |
6 |
T9038 |
1051-1053 |
NN |
denotes |
mo |
T9039 |
1054-1055 |
SYM |
denotes |
+ |
T9040 |
1056-1057 |
CD |
denotes |
3 |
T9041 |
1058-1060 |
NN |
denotes |
mo |
T9042 |
1061-1064 |
CC |
denotes |
and |
T9043 |
1065-1066 |
CD |
denotes |
6 |
T9044 |
1067-1069 |
NN |
denotes |
mo |
T9045 |
1070-1071 |
SYM |
denotes |
+ |
T9046 |
1072-1073 |
CD |
denotes |
6 |
T9047 |
1074-1076 |
NN |
denotes |
mo |
T9048 |
1077-1084 |
VBN |
denotes |
treated |
T9049 |
1098-1102 |
RBS |
denotes |
most |
T9050 |
1103-1110 |
JJ |
denotes |
similar |
T9051 |
1111-1113 |
IN |
denotes |
to |
T9052 |
1114-1118 |
DT |
denotes |
that |
T9053 |
1119-1121 |
IN |
denotes |
of |
T9054 |
1122-1125 |
DT |
denotes |
the |
T9055 |
1141-1147 |
NN |
denotes |
cohort |
T9056 |
1126-1127 |
CD |
denotes |
9 |
T9057 |
1128-1130 |
NN |
denotes |
mo |
T9058 |
1131-1140 |
JJ |
denotes |
untreated |
T9059 |
1147-1149 |
, |
denotes |
, |
T9060 |
1149-1159 |
VBG |
denotes |
suggesting |
T9061 |
1160-1164 |
IN |
denotes |
that |
T9062 |
1255-1264 |
VB |
denotes |
determine |
T9063 |
1165-1168 |
NN |
denotes |
age |
T9064 |
1168-1170 |
, |
denotes |
, |
T9065 |
1170-1172 |
IN |
denotes |
as |
T9066 |
1173-1180 |
VBN |
denotes |
opposed |
T9067 |
1181-1183 |
IN |
denotes |
to |
T9068 |
1184-1193 |
JJ |
denotes |
synthetic |
T9069 |
1194-1198 |
NN |
denotes |
rate |
T9070 |
1199-1200 |
-LRB- |
denotes |
( |
T9071 |
1200-1205 |
WDT |
denotes |
which |
T9072 |
1212-1214 |
VB |
denotes |
be |
T9073 |
1206-1211 |
MD |
denotes |
would |
T9074 |
1215-1225 |
JJ |
denotes |
negligible |
T9075 |
1226-1228 |
IN |
denotes |
in |
T9076 |
1229-1232 |
DT |
denotes |
the |
T9077 |
1241-1248 |
NNS |
denotes |
animals |
T9078 |
1233-1240 |
VBN |
denotes |
treated |
T9079 |
1248-1249 |
-RRB- |
denotes |
) |
T9080 |
1249-1251 |
, |
denotes |
, |
T9081 |
1251-1254 |
MD |
denotes |
may |
T9082 |
1265-1268 |
DT |
denotes |
the |
T9083 |
1269-1277 |
NN |
denotes |
fraction |
T9084 |
1278-1280 |
IN |
denotes |
of |
T9085 |
1281-1284 |
NN |
denotes |
PBS |
T9086 |
1285-1292 |
JJ |
denotes |
soluble |
T9087 |
1284-1285 |
HYPH |
denotes |
- |
T9088 |
1293-1295 |
NN |
denotes |
Aβ |
T9089 |
1296-1298 |
IN |
denotes |
in |
T9090 |
1299-1304 |
DT |
denotes |
these |
T9091 |
1305-1312 |
NNS |
denotes |
animals |
T9092 |
1312-1313 |
. |
denotes |
. |
R6118 |
T8814 |
T8811 |
prep |
in,measure |
R6123 |
T8815 |
T8816 |
det |
the,brains |
R6127 |
T8816 |
T8814 |
pobj |
brains,in |
R6129 |
T8817 |
T8816 |
prep |
of,brains |
R6130 |
T8818 |
T8819 |
det |
each,group |
R6133 |
T8819 |
T8817 |
pobj |
group,of |
R6137 |
T8820 |
T8821 |
aux |
to,determine |
R6140 |
T8821 |
T8811 |
advcl |
determine,measure |
R6143 |
T8822 |
T8823 |
mark |
whether,occurred |
R6145 |
T8806 |
T8807 |
nsubj |
We,used |
R6146 |
T8808 |
T8807 |
advmod |
next,used |
R6147 |
T8823 |
T8821 |
ccomp |
occurred,determine |
R6148 |
T8809 |
T8807 |
dobj |
ELISA,used |
R6149 |
T8810 |
T8811 |
aux |
to,measure |
R6150 |
T8824 |
T8825 |
det |
any,change |
R6151 |
T8811 |
T8807 |
advcl |
measure,used |
R6152 |
T8812 |
T8813 |
amod |
total,Aβ |
R6153 |
T8813 |
T8811 |
dobj |
Aβ,measure |
R6154 |
T8825 |
T8823 |
nsubj |
change,occurred |
R6155 |
T8826 |
T8825 |
prep |
in,change |
R6156 |
T8827 |
T8828 |
det |
the,amount |
R6157 |
T8828 |
T8826 |
pobj |
amount,in |
R6158 |
T8829 |
T8828 |
cc |
or,amount |
R6159 |
T8830 |
T8828 |
conj |
solubility,amount |
R6160 |
T8920 |
T8918 |
prep |
with,Consistent |
R6161 |
T8921 |
T8922 |
det |
the,results |
R6162 |
T8831 |
T8828 |
prep |
of,amount |
R6163 |
T8922 |
T8920 |
pobj |
results,with |
R6164 |
T8923 |
T8922 |
compound |
filter,results |
R6165 |
T8832 |
T8831 |
pobj |
peptide,of |
R6166 |
T8924 |
T8922 |
compound |
trap,results |
R6167 |
T8925 |
T8922 |
acl |
presented,results |
R6168 |
T8926 |
T8925 |
advmod |
above,presented |
R6169 |
T8833 |
T8834 |
mark |
while,suppressed |
R6170 |
T8927 |
T8919 |
punct |
", ",were |
R6171 |
T8928 |
T8919 |
expl |
there,were |
R6172 |
T8834 |
T8823 |
advcl |
suppressed,occurred |
R6173 |
T8929 |
T8930 |
det |
no,differences |
R6174 |
T8930 |
T8919 |
attr |
differences,were |
R6175 |
T8931 |
T8930 |
amod |
significant,differences |
R6176 |
T8835 |
T8836 |
compound |
APPswe,ind |
R6177 |
T8932 |
T8930 |
prep |
in,differences |
R6178 |
T8933 |
T8934 |
npadvmod |
SDS,soluble |
R6179 |
T8836 |
T8838 |
compound |
ind,expression |
R6180 |
T8934 |
T8939 |
amod |
soluble,Aβ |
R6181 |
T8935 |
T8933 |
punct |
-,SDS |
R6182 |
T8936 |
T8933 |
cc |
or,SDS |
R6183 |
T8837 |
T8836 |
punct |
/,ind |
R6184 |
T8937 |
T8933 |
conj |
FA,SDS |
R6185 |
T8938 |
T8934 |
punct |
-,soluble |
R6186 |
T8939 |
T8932 |
pobj |
Aβ,in |
R6187 |
T8838 |
T8834 |
nsubjpass |
expression,suppressed |
R6188 |
T8940 |
T8930 |
prep |
between,differences |
R6189 |
T8941 |
T8942 |
det |
the,cohort |
R6190 |
T8839 |
T8834 |
auxpass |
was,suppressed |
R6191 |
T8942 |
T8940 |
pobj |
cohort,between |
R6192 |
T8943 |
T8944 |
nummod |
6,mo |
R6193 |
T8944 |
T8942 |
nmod |
mo,cohort |
R6194 |
T8840 |
T8807 |
punct |
.,used |
R6195 |
T8945 |
T8942 |
amod |
untreated,cohort |
R6196 |
T8946 |
T8942 |
cc |
and,cohort |
R6197 |
T8947 |
T8948 |
preconj |
either,cohorts |
R6198 |
T8948 |
T8942 |
conj |
cohorts,cohort |
R6199 |
T8949 |
T8948 |
det |
the,cohorts |
R6200 |
T8842 |
T8843 |
amod |
Cortical,homogenates |
R6201 |
T8950 |
T8951 |
nummod |
6,mo |
R6202 |
T8951 |
T8948 |
nmod |
mo,cohorts |
R6203 |
T8952 |
T8951 |
punct |
+,mo |
R6204 |
T8843 |
T8844 |
nsubjpass |
homogenates,extracted |
R6205 |
T8953 |
T8954 |
nummod |
3,mo |
R6206 |
T8954 |
T8951 |
appos |
mo,mo |
R6207 |
T8955 |
T8954 |
acl |
treated,mo |
R6208 |
T8844 |
T8847 |
ccomp |
extracted,measured |
R6209 |
T8956 |
T8951 |
cc |
or,mo |
R6210 |
T8957 |
T8958 |
nummod |
6,mo |
R6211 |
T8958 |
T8951 |
conj |
mo,mo |
R6212 |
T8845 |
T8844 |
auxpass |
were,extracted |
R6213 |
T8959 |
T8958 |
punct |
+,mo |
R6214 |
T8960 |
T8961 |
nummod |
6,mo |
R6215 |
T8846 |
T8844 |
advmod |
sequentially,extracted |
R6216 |
T8961 |
T8958 |
appos |
mo,mo |
R6217 |
T8962 |
T8961 |
acl |
treated,mo |
R6218 |
T8963 |
T8919 |
punct |
.,were |
R6219 |
T8848 |
T8849 |
aux |
to,separate |
R6220 |
T8965 |
T8966 |
advmod |
However,contained |
R6221 |
T8849 |
T8844 |
advcl |
separate,extracted |
R6222 |
T8850 |
T8849 |
dobj |
peptide,separate |
R6223 |
T8967 |
T8966 |
punct |
", ",contained |
R6224 |
T8968 |
T8966 |
nsubj |
brains,contained |
R6225 |
T8851 |
T8849 |
prep |
into,separate |
R6226 |
T8969 |
T8968 |
prep |
of,brains |
R6227 |
T8970 |
T8971 |
preconj |
both,mo |
R6228 |
T8971 |
T8973 |
npadvmod |
mo,treated |
R6229 |
T8852 |
T8853 |
npadvmod |
PBS,soluble |
R6230 |
T8972 |
T8971 |
nummod |
6,mo |
R6231 |
T8973 |
T8983 |
amod |
treated,cohorts |
R6232 |
T8853 |
T8862 |
amod |
soluble,fractions |
R6233 |
T8974 |
T8971 |
punct |
+,mo |
R6234 |
T8975 |
T8976 |
nummod |
3,mo |
R6235 |
T8854 |
T8852 |
punct |
-,PBS |
R6236 |
T8976 |
T8971 |
appos |
mo,mo |
R6237 |
T8977 |
T8971 |
cc |
and,mo |
R6238 |
T8978 |
T8979 |
nummod |
6,mo |
R6239 |
T8855 |
T8852 |
punct |
", ",PBS |
R6240 |
T8979 |
T8971 |
conj |
mo,mo |
R6241 |
T8980 |
T8979 |
punct |
+,mo |
R6242 |
T8981 |
T8982 |
nummod |
6,mo |
R6243 |
T8856 |
T8852 |
conj |
SDS,PBS |
R6244 |
T8982 |
T8979 |
appos |
mo,mo |
R6245 |
T8983 |
T8969 |
pobj |
cohorts,of |
R6246 |
T8857 |
T8856 |
punct |
-,SDS |
R6247 |
T8984 |
T8985 |
advmod |
roughly,twice |
R6248 |
T8985 |
T8986 |
advmod |
twice,much |
R6249 |
T8986 |
T8988 |
amod |
much,Aβ40 |
R6250 |
T8987 |
T8986 |
advmod |
as,much |
R6251 |
T8988 |
T8966 |
dobj |
Aβ40,contained |
R6252 |
T8858 |
T8856 |
punct |
", ",SDS |
R6253 |
T8989 |
T8988 |
nmod |
PBS,Aβ40 |
R6254 |
T8990 |
T8988 |
punct |
-,Aβ40 |
R6255 |
T8991 |
T8988 |
amod |
soluble,Aβ40 |
R6256 |
T8859 |
T8856 |
cc |
and,SDS |
R6257 |
T8992 |
T8988 |
prep |
as,Aβ40 |
R6258 |
T8993 |
T8994 |
amod |
untreated,mice |
R6259 |
T8860 |
T8856 |
conj |
FA,SDS |
R6260 |
T8994 |
T8992 |
pobj |
mice,as |
R6261 |
T8995 |
T8996 |
nummod |
6,mo |
R6262 |
T8996 |
T8998 |
npadvmod |
mo,old |
R6263 |
T8861 |
T8853 |
punct |
-,soluble |
R6264 |
T8997 |
T8996 |
punct |
-,mo |
R6265 |
T8998 |
T8994 |
amod |
old,mice |
R6266 |
T8862 |
T8851 |
pobj |
fractions,into |
R6267 |
T8999 |
T8998 |
punct |
-,old |
R6268 |
T9000 |
T9001 |
punct |
(,5C |
R6269 |
T8863 |
T8847 |
punct |
", ",measured |
R6270 |
T9001 |
T8966 |
parataxis |
5C,contained |
R6271 |
T9002 |
T9001 |
compound |
Figure,5C |
R6272 |
T9003 |
T9001 |
punct |
),5C |
R6273 |
T8864 |
T8847 |
advmod |
then,measured |
R6274 |
T9004 |
T8966 |
punct |
.,contained |
R6275 |
T8865 |
T8866 |
npadvmod |
transgene,derived |
R6276 |
T9006 |
T9007 |
nsubj |
Levels,showed |
R6277 |
T9008 |
T9006 |
prep |
of,Levels |
R6278 |
T8866 |
T8868 |
amod |
derived,Aβ40 |
R6279 |
T9009 |
T9008 |
pobj |
Aβ42,of |
R6280 |
T9010 |
T9011 |
det |
a,trend |
R6281 |
T8867 |
T8866 |
punct |
-,derived |
R6282 |
T9011 |
T9007 |
dobj |
trend,showed |
R6283 |
T9012 |
T9011 |
amod |
similar,trend |
R6284 |
T9013 |
T9007 |
punct |
", ",showed |
R6285 |
T8868 |
T8847 |
nsubjpass |
Aβ40,measured |
R6286 |
T9014 |
T9007 |
cc |
but,showed |
R6287 |
T9015 |
T9016 |
aux |
did,reach |
R6288 |
T8869 |
T8868 |
cc |
and,Aβ40 |
R6289 |
T9016 |
T9007 |
conj |
reach,showed |
R6290 |
T9017 |
T9016 |
neg |
not,reach |
R6291 |
T9018 |
T9019 |
amod |
statistical,significance |
R6292 |
T8870 |
T8868 |
conj |
Aβ42,Aβ40 |
R6293 |
T9019 |
T9016 |
dobj |
significance,reach |
R6294 |
T9020 |
T9007 |
punct |
.,showed |
R6295 |
T8871 |
T8847 |
auxpass |
were,measured |
R6296 |
T9022 |
T9023 |
prep |
In,were |
R6297 |
T8872 |
T8847 |
agent |
by,measured |
R6298 |
T9024 |
T9022 |
pobj |
fact,In |
R6299 |
T8873 |
T8874 |
amod |
human,specific |
R6300 |
T9025 |
T9023 |
punct |
", ",were |
R6301 |
T9026 |
T9023 |
nsubj |
levels,were |
R6302 |
T8874 |
T8876 |
amod |
specific,ELISA |
R6303 |
T9027 |
T9026 |
prep |
of,levels |
R6304 |
T9028 |
T9029 |
npadvmod |
PBS,soluble |
R6305 |
T9029 |
T9031 |
amod |
soluble,Aβ40 |
R6306 |
T8875 |
T8874 |
punct |
-,specific |
R6307 |
T9030 |
T9029 |
punct |
-,soluble |
R6308 |
T9031 |
T9027 |
pobj |
Aβ40,of |
R6309 |
T8876 |
T8872 |
pobj |
ELISA,by |
R6310 |
T9032 |
T9031 |
cc |
and,Aβ40 |
R6311 |
T9033 |
T9031 |
conj |
Aβ42,Aβ40 |
R6312 |
T9034 |
T9026 |
prep |
in,levels |
R6313 |
T8877 |
T8878 |
punct |
[,23 |
R6314 |
T9035 |
T9036 |
det |
the,cohorts |
R6315 |
T9036 |
T9034 |
pobj |
cohorts,in |
R6316 |
T8878 |
T8847 |
parataxis |
23,measured |
R6317 |
T9037 |
T9038 |
nummod |
6,mo |
R6318 |
T9038 |
T9036 |
nmod |
mo,cohorts |
R6319 |
T9039 |
T9038 |
punct |
+,mo |
R6320 |
T8879 |
T8878 |
punct |
],23 |
R6321 |
T9040 |
T9041 |
nummod |
3,mo |
R6322 |
T9041 |
T9038 |
appos |
mo,mo |
R6323 |
T8880 |
T8847 |
punct |
.,measured |
R6324 |
T9042 |
T9038 |
cc |
and,mo |
R6325 |
T9043 |
T9044 |
nummod |
6,mo |
R6326 |
T9044 |
T9038 |
conj |
mo,mo |
R6327 |
T8882 |
T8883 |
prep |
In,found |
R6328 |
T9045 |
T9044 |
punct |
+,mo |
R6329 |
T9046 |
T9047 |
nummod |
6,mo |
R6330 |
T9047 |
T9044 |
appos |
mo,mo |
R6331 |
T9048 |
T9044 |
acl |
treated,mo |
R6332 |
T8884 |
T8885 |
det |
all,animals |
R6333 |
T9049 |
T9050 |
advmod |
most,similar |
R6334 |
T9050 |
T9023 |
acomp |
similar,were |
R6335 |
T9051 |
T9050 |
prep |
to,similar |
R6336 |
T8885 |
T8882 |
pobj |
animals,In |
R6337 |
T8886 |
T8885 |
acl |
harboring,animals |
R6338 |
T9052 |
T9051 |
pobj |
that,to |
R6339 |
T9053 |
T9052 |
prep |
of,that |
R6340 |
T8887 |
T8888 |
compound |
amyloid,deposits |
R6341 |
T9054 |
T9055 |
det |
the,cohort |
R6342 |
T9055 |
T9053 |
pobj |
cohort,of |
R6343 |
T9056 |
T9057 |
nummod |
9,mo |
R6344 |
T8888 |
T8886 |
dobj |
deposits,harboring |
R6345 |
T9057 |
T9055 |
nmod |
mo,cohort |
R6346 |
T9058 |
T9055 |
amod |
untreated,cohort |
R6347 |
T8889 |
T8883 |
punct |
", ",found |
R6348 |
T9059 |
T9023 |
punct |
", ",were |
R6349 |
T9060 |
T9023 |
advcl |
suggesting,were |
R6350 |
T8890 |
T8883 |
nsubj |
we,found |
R6351 |
T9061 |
T9062 |
mark |
that,determine |
R6352 |
T9062 |
T9060 |
ccomp |
determine,suggesting |
R6353 |
T9063 |
T9062 |
nsubj |
age,determine |
R6354 |
T9064 |
T9063 |
punct |
", ",age |
R6355 |
T9065 |
T9063 |
prep |
as,age |
R6356 |
T9066 |
T9065 |
prep |
opposed,as |
R6357 |
T8891 |
T8892 |
mark |
that,extracted |
R6358 |
T9067 |
T9066 |
prep |
to,opposed |
R6359 |
T9068 |
T9069 |
amod |
synthetic,rate |
R6360 |
T8892 |
T8883 |
ccomp |
extracted,found |
R6361 |
T9069 |
T9067 |
pobj |
rate,to |
R6362 |
T9070 |
T9069 |
punct |
(,rate |
R6363 |
T9071 |
T9072 |
dep |
which,be |
R6364 |
T8893 |
T8894 |
det |
the,majority |
R6365 |
T9072 |
T9069 |
relcl |
be,rate |
R6366 |
T9073 |
T9072 |
aux |
would,be |
R6367 |
T8894 |
T8892 |
nsubjpass |
majority,extracted |
R6368 |
T9074 |
T9072 |
acomp |
negligible,be |
R6369 |
T9075 |
T9072 |
prep |
in,be |
R6370 |
T9076 |
T9077 |
det |
the,animals |
R6371 |
T8895 |
T8894 |
amod |
vast,majority |
R6372 |
T9077 |
T9075 |
pobj |
animals,in |
R6373 |
T9078 |
T9077 |
amod |
treated,animals |
R6374 |
T9079 |
T9062 |
punct |
),determine |
R6375 |
T8896 |
T8894 |
prep |
of,majority |
R6376 |
T9080 |
T9062 |
punct |
", ",determine |
R6377 |
T9081 |
T9062 |
aux |
may,determine |
R6378 |
T9082 |
T9083 |
det |
the,fraction |
R6379 |
T8897 |
T8896 |
pobj |
Aβ,of |
R6380 |
T9083 |
T9062 |
dobj |
fraction,determine |
R6381 |
T9084 |
T9083 |
prep |
of,fraction |
R6382 |
T8898 |
T8899 |
punct |
(,% |
R6383 |
T9085 |
T9086 |
npadvmod |
PBS,soluble |
R6384 |
T9086 |
T9088 |
amod |
soluble,Aβ |
R6385 |
T9087 |
T9086 |
punct |
-,soluble |
R6386 |
T8899 |
T8897 |
parataxis |
%,Aβ |
R6387 |
T9088 |
T9084 |
pobj |
Aβ,of |
R6388 |
T9089 |
T9062 |
prep |
in,determine |
R6389 |
T9090 |
T9091 |
det |
these,animals |
R6390 |
T8900 |
T8901 |
punct |
>,99 |
R6391 |
T9091 |
T9089 |
pobj |
animals,in |
R6392 |
T9092 |
T9023 |
punct |
.,were |
R6393 |
T8901 |
T8899 |
nummod |
99,% |
R6395 |
T8902 |
T8899 |
punct |
),% |
R6398 |
T8903 |
T8892 |
auxpass |
was,extracted |
R6402 |
T8904 |
T8892 |
prep |
into,extracted |
R6408 |
T8905 |
T8906 |
det |
the,fractions |
R6411 |
T8906 |
T8904 |
pobj |
fractions,into |
R6415 |
T8907 |
T8906 |
nmod |
SDS,fractions |
R6418 |
T8908 |
T8907 |
cc |
and,SDS |
R6422 |
T8909 |
T8907 |
conj |
FA,SDS |
R6425 |
T8910 |
T8911 |
punct |
(,5A |
R6429 |
T8911 |
T8892 |
parataxis |
5A,extracted |
R6431 |
T8912 |
T8911 |
compound |
Figure,5A |
R6435 |
T8913 |
T8911 |
cc |
and,5A |
R6438 |
T8914 |
T8911 |
conj |
5B,5A |
R6441 |
T8915 |
T8911 |
punct |
),5A |
R6442 |
T8916 |
T8883 |
punct |
.,found |
R6443 |
T8918 |
T8919 |
advcl |
Consistent,were |