PMC:1283364 / 21595-21846 JSONTXT

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Compared to a standard APP transgenic line used for previous amyloid studies by our laboratory (line C3–3; [15,26,27]), we estimated that the four controllable lines produce transgenic APP protein at 10- to 30-fold over endogenous levels (Figure S1)."}

{"project":"2_test","denotations":[{"id":"16279840-9117892-86242766","span":{"begin":109,"end":111},"obj":"9117892"},{"id":"16279840-14645205-86242767","span":{"begin":112,"end":114},"obj":"14645205"},{"id":"16279840-9354339-86242768","span":{"begin":115,"end":117},"obj":"9354339"},{"id":"T248","span":{"begin":109,"end":111},"obj":"9117892"},{"id":"T42200","span":{"begin":112,"end":114},"obj":"14645205"},{"id":"T15428","span":{"begin":115,"end":117},"obj":"9354339"}],"text":" Compared to a standard APP transgenic line used for previous amyloid studies by our laboratory (line C3–3; [15,26,27]), we estimated that the four controllable lines produce transgenic APP protein at 10- to 30-fold over endogenous levels (Figure S1)."}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T6134","span":{"begin":24,"end":27},"obj":"PR_EXT:000004168"},{"id":"T6135","span":{"begin":28,"end":38},"obj":"SO_EXT:transgenic_entity"},{"id":"T6136","span":{"begin":62,"end":69},"obj":"CHEBI:60425"},{"id":"T6137","span":{"begin":175,"end":185},"obj":"SO_EXT:transgenic_entity"},{"id":"T6138","span":{"begin":186,"end":189},"obj":"PR_EXT:000004168"},{"id":"T6139","span":{"begin":190,"end":197},"obj":"CHEBI_PR_EXT:protein"}],"text":" Compared to a standard APP transgenic line used for previous amyloid studies by our laboratory (line C3–3; [15,26,27]), we estimated that the four controllable lines produce transgenic APP protein at 10- to 30-fold over endogenous levels (Figure S1)."}

{"project":"craft-ca-core-dev","denotations":[{"id":"T5840","span":{"begin":24,"end":27},"obj":"PR:000004168"},{"id":"T5841","span":{"begin":62,"end":69},"obj":"CHEBI:60425"},{"id":"T5842","span":{"begin":186,"end":189},"obj":"PR:000004168"}],"text":" Compared to a standard APP transgenic line used for previous amyloid studies by our laboratory (line C3–3; [15,26,27]), we estimated that the four controllable lines produce transgenic APP protein at 10- to 30-fold over endogenous levels (Figure S1)."}