Id |
Subject |
Object |
Predicate |
Lexical cue |
T5502 |
0-5 |
IN |
denotes |
While |
T5503 |
61-67 |
VBD |
denotes |
showed |
T5504 |
6-9 |
DT |
denotes |
the |
T5505 |
52-60 |
NN |
denotes |
behavior |
T5506 |
10-18 |
VBN |
denotes |
improved |
T5507 |
19-23 |
NN |
denotes |
odor |
T5508 |
24-38 |
NN |
denotes |
discrimination |
T5509 |
39-42 |
CC |
denotes |
and |
T5510 |
43-51 |
NN |
denotes |
learning |
T5511 |
166-169 |
VBD |
denotes |
was |
T5512 |
68-72 |
RB |
denotes |
only |
T5513 |
80-91 |
NN |
denotes |
variability |
T5514 |
73-79 |
JJ |
denotes |
little |
T5515 |
91-93 |
, |
denotes |
, |
T5516 |
93-96 |
DT |
denotes |
the |
T5517 |
127-138 |
NN |
denotes |
performance |
T5518 |
97-110 |
RB |
denotes |
significantly |
T5519 |
111-119 |
VBN |
denotes |
impaired |
T5520 |
120-126 |
NN |
denotes |
memory |
T5521 |
139-147 |
VBN |
denotes |
observed |
T5522 |
148-150 |
IN |
denotes |
in |
T5523 |
151-155 |
NN |
denotes |
GluR |
T5524 |
156-160 |
NN |
denotes |
BΔFB |
T5525 |
155-156 |
HYPH |
denotes |
- |
T5526 |
161-165 |
NNS |
denotes |
mice |
T5527 |
170-176 |
RB |
denotes |
highly |
T5528 |
177-185 |
JJ |
denotes |
variable |
T5529 |
186-191 |
IN |
denotes |
among |
T5530 |
192-202 |
JJ |
denotes |
individual |
T5531 |
203-210 |
NNS |
denotes |
animals |
T5532 |
211-219 |
VBN |
denotes |
compared |
T5533 |
220-224 |
IN |
denotes |
with |
T5534 |
225-232 |
NN |
denotes |
control |
T5535 |
233-244 |
NNS |
denotes |
littermates |
T5536 |
245-246 |
-LRB- |
denotes |
( |
T5537 |
253-255 |
NN |
denotes |
2E |
T5538 |
246-252 |
NN |
denotes |
Figure |
T5539 |
255-256 |
-RRB- |
denotes |
) |
T5540 |
256-257 |
. |
denotes |
. |
T5541 |
257-470 |
sentence |
denotes |
This variability in olfactory memory was reflected in the level and extent of Cre-recombinase expression in forebrain of transgenic TgCre4 mice, as visualized by Cre-activity in the Cre-indicator mouse line R26R. |
T5542 |
258-262 |
DT |
denotes |
This |
T5543 |
263-274 |
NN |
denotes |
variability |
T5544 |
299-308 |
VBN |
denotes |
reflected |
T5545 |
275-277 |
IN |
denotes |
in |
T5546 |
278-287 |
JJ |
denotes |
olfactory |
T5547 |
288-294 |
NN |
denotes |
memory |
T5548 |
295-298 |
VBD |
denotes |
was |
T5549 |
309-311 |
IN |
denotes |
in |
T5550 |
312-315 |
DT |
denotes |
the |
T5551 |
316-321 |
NN |
denotes |
level |
T5552 |
322-325 |
CC |
denotes |
and |
T5553 |
326-332 |
NN |
denotes |
extent |
T5554 |
333-335 |
IN |
denotes |
of |
T5555 |
336-339 |
NN |
denotes |
Cre |
T5556 |
340-351 |
NN |
denotes |
recombinase |
T5557 |
339-340 |
HYPH |
denotes |
- |
T5558 |
352-362 |
NN |
denotes |
expression |
T5559 |
363-365 |
IN |
denotes |
in |
T5560 |
366-375 |
NN |
denotes |
forebrain |
T5561 |
376-378 |
IN |
denotes |
of |
T5562 |
379-389 |
JJ |
denotes |
transgenic |
T5563 |
397-401 |
NNS |
denotes |
mice |
T5564 |
390-396 |
NN |
denotes |
TgCre4 |
T5565 |
401-403 |
, |
denotes |
, |
T5566 |
403-405 |
IN |
denotes |
as |
T5567 |
406-416 |
VBN |
denotes |
visualized |
T5568 |
417-419 |
IN |
denotes |
by |
T5569 |
420-423 |
NN |
denotes |
Cre |
T5570 |
424-432 |
NN |
denotes |
activity |
T5571 |
423-424 |
HYPH |
denotes |
- |
T5572 |
433-435 |
IN |
denotes |
in |
T5573 |
436-439 |
DT |
denotes |
the |
T5574 |
460-464 |
NN |
denotes |
line |
T5575 |
440-443 |
NN |
denotes |
Cre |
T5576 |
444-453 |
NN |
denotes |
indicator |
T5577 |
443-444 |
HYPH |
denotes |
- |
T5578 |
454-459 |
NN |
denotes |
mouse |
T5579 |
465-469 |
NN |
denotes |
R26R |
T5580 |
469-470 |
. |
denotes |
. |
T5581 |
470-718 |
sentence |
denotes |
We observed that onset and extent of Cre-recombinase expression in different forebrain regions varied among individual TgCre4 mice (Figure 3A), which could also be directly visualized by immunohistochemistry with a Cre-antibody (unpublished data). |
T5582 |
471-473 |
PRP |
denotes |
We |
T5583 |
474-482 |
VBD |
denotes |
observed |
T5584 |
483-487 |
IN |
denotes |
that |
T5585 |
566-572 |
VBD |
denotes |
varied |
T5586 |
488-493 |
NN |
denotes |
onset |
T5587 |
494-497 |
CC |
denotes |
and |
T5588 |
498-504 |
NN |
denotes |
extent |
T5589 |
505-507 |
IN |
denotes |
of |
T5590 |
508-511 |
NN |
denotes |
Cre |
T5591 |
512-523 |
NN |
denotes |
recombinase |
T5592 |
511-512 |
HYPH |
denotes |
- |
T5593 |
524-534 |
NN |
denotes |
expression |
T5594 |
535-537 |
IN |
denotes |
in |
T5595 |
538-547 |
JJ |
denotes |
different |
T5596 |
558-565 |
NNS |
denotes |
regions |
T5597 |
548-557 |
NN |
denotes |
forebrain |
T5598 |
573-578 |
IN |
denotes |
among |
T5599 |
579-589 |
JJ |
denotes |
individual |
T5600 |
597-601 |
NNS |
denotes |
mice |
T5601 |
590-596 |
NN |
denotes |
TgCre4 |
T5602 |
602-603 |
-LRB- |
denotes |
( |
T5603 |
610-612 |
NN |
denotes |
3A |
T5604 |
603-609 |
NN |
denotes |
Figure |
T5605 |
612-613 |
-RRB- |
denotes |
) |
T5606 |
613-615 |
, |
denotes |
, |
T5607 |
615-620 |
WDT |
denotes |
which |
T5608 |
644-654 |
VBN |
denotes |
visualized |
T5609 |
621-626 |
MD |
denotes |
could |
T5610 |
627-631 |
RB |
denotes |
also |
T5611 |
632-634 |
VB |
denotes |
be |
T5612 |
635-643 |
RB |
denotes |
directly |
T5613 |
655-657 |
IN |
denotes |
by |
T5614 |
658-678 |
NN |
denotes |
immunohistochemistry |
T5615 |
679-683 |
IN |
denotes |
with |
T5616 |
684-685 |
DT |
denotes |
a |
T5617 |
690-698 |
NN |
denotes |
antibody |
T5618 |
686-689 |
NN |
denotes |
Cre |
T5619 |
689-690 |
HYPH |
denotes |
- |
T5620 |
699-700 |
-LRB- |
denotes |
( |
T5621 |
712-716 |
NNS |
denotes |
data |
T5622 |
700-711 |
JJ |
denotes |
unpublished |
T5623 |
716-717 |
-RRB- |
denotes |
) |
T5624 |
717-718 |
. |
denotes |
. |
T5625 |
718-975 |
sentence |
denotes |
As this variability persisted after several backcrosses, and Southern blot analysis revealed no differences of transgene integration or number among animals (Figure 3B), it could not be attributed to genetic differences but rather to epigenetic mechanisms. |
T5626 |
719-721 |
IN |
denotes |
As |
T5627 |
739-748 |
VBD |
denotes |
persisted |
T5628 |
722-726 |
DT |
denotes |
this |
T5629 |
727-738 |
NN |
denotes |
variability |
T5630 |
905-915 |
VBN |
denotes |
attributed |
T5631 |
749-754 |
IN |
denotes |
after |
T5632 |
755-762 |
JJ |
denotes |
several |
T5633 |
763-774 |
NNS |
denotes |
backcrosses |
T5634 |
774-776 |
, |
denotes |
, |
T5635 |
776-779 |
CC |
denotes |
and |
T5636 |
780-788 |
NNP |
denotes |
Southern |
T5637 |
789-793 |
NN |
denotes |
blot |
T5638 |
794-802 |
NN |
denotes |
analysis |
T5639 |
803-811 |
VBD |
denotes |
revealed |
T5640 |
812-814 |
DT |
denotes |
no |
T5641 |
815-826 |
NNS |
denotes |
differences |
T5642 |
827-829 |
IN |
denotes |
of |
T5643 |
830-839 |
NN |
denotes |
transgene |
T5644 |
840-851 |
NN |
denotes |
integration |
T5645 |
852-854 |
CC |
denotes |
or |
T5646 |
855-861 |
NN |
denotes |
number |
T5647 |
862-867 |
IN |
denotes |
among |
T5648 |
868-875 |
NNS |
denotes |
animals |
T5649 |
876-877 |
-LRB- |
denotes |
( |
T5650 |
884-886 |
NN |
denotes |
3B |
T5651 |
877-883 |
NN |
denotes |
Figure |
T5652 |
886-887 |
-RRB- |
denotes |
) |
T5653 |
887-889 |
, |
denotes |
, |
T5654 |
889-891 |
PRP |
denotes |
it |
T5655 |
892-897 |
MD |
denotes |
could |
T5656 |
898-901 |
RB |
denotes |
not |
T5657 |
902-904 |
VB |
denotes |
be |
T5658 |
916-918 |
IN |
denotes |
to |
T5659 |
919-926 |
JJ |
denotes |
genetic |
T5660 |
927-938 |
NNS |
denotes |
differences |
T5661 |
939-942 |
CC |
denotes |
but |
T5662 |
943-949 |
RB |
denotes |
rather |
T5663 |
950-952 |
IN |
denotes |
to |
T5664 |
953-963 |
JJ |
denotes |
epigenetic |
T5665 |
964-974 |
NNS |
denotes |
mechanisms |
T5666 |
974-975 |
. |
denotes |
. |
R3691 |
T5502 |
T5503 |
mark |
While,showed |
R3692 |
T5503 |
T5511 |
advcl |
showed,was |
R3693 |
T5504 |
T5505 |
det |
the,behavior |
R3694 |
T5505 |
T5503 |
nsubj |
behavior,showed |
R3695 |
T5506 |
T5505 |
amod |
improved,behavior |
R3696 |
T5507 |
T5508 |
nmod |
odor,discrimination |
R3697 |
T5508 |
T5505 |
nmod |
discrimination,behavior |
R3698 |
T5509 |
T5508 |
cc |
and,discrimination |
R3699 |
T5510 |
T5508 |
conj |
learning,discrimination |
R3700 |
T5512 |
T5513 |
advmod |
only,variability |
R3701 |
T5513 |
T5503 |
dobj |
variability,showed |
R3702 |
T5514 |
T5513 |
amod |
little,variability |
R3703 |
T5515 |
T5511 |
punct |
", ",was |
R3704 |
T5516 |
T5517 |
det |
the,performance |
R3705 |
T5517 |
T5511 |
nsubj |
performance,was |
R3706 |
T5518 |
T5519 |
advmod |
significantly,impaired |
R3707 |
T5519 |
T5517 |
amod |
impaired,performance |
R3708 |
T5520 |
T5517 |
compound |
memory,performance |
R3709 |
T5521 |
T5517 |
acl |
observed,performance |
R3710 |
T5522 |
T5521 |
prep |
in,observed |
R3711 |
T5523 |
T5524 |
compound |
GluR,BΔFB |
R3712 |
T5524 |
T5526 |
compound |
BΔFB,mice |
R3713 |
T5525 |
T5524 |
punct |
-,BΔFB |
R3714 |
T5526 |
T5522 |
pobj |
mice,in |
R3715 |
T5527 |
T5528 |
advmod |
highly,variable |
R3716 |
T5528 |
T5511 |
acomp |
variable,was |
R3717 |
T5529 |
T5511 |
prep |
among,was |
R3718 |
T5530 |
T5531 |
amod |
individual,animals |
R3719 |
T5531 |
T5529 |
pobj |
animals,among |
R3720 |
T5532 |
T5511 |
prep |
compared,was |
R3721 |
T5533 |
T5532 |
prep |
with,compared |
R3722 |
T5534 |
T5535 |
compound |
control,littermates |
R3723 |
T5535 |
T5533 |
pobj |
littermates,with |
R3724 |
T5536 |
T5537 |
punct |
(,2E |
R3725 |
T5537 |
T5511 |
parataxis |
2E,was |
R3726 |
T5538 |
T5537 |
compound |
Figure,2E |
R3727 |
T5539 |
T5537 |
punct |
),2E |
R3728 |
T5540 |
T5511 |
punct |
.,was |
R3729 |
T5542 |
T5543 |
det |
This,variability |
R3730 |
T5543 |
T5544 |
nsubjpass |
variability,reflected |
R3731 |
T5545 |
T5543 |
prep |
in,variability |
R3732 |
T5546 |
T5547 |
amod |
olfactory,memory |
R3733 |
T5547 |
T5545 |
pobj |
memory,in |
R3734 |
T5548 |
T5544 |
auxpass |
was,reflected |
R3735 |
T5549 |
T5544 |
prep |
in,reflected |
R3736 |
T5550 |
T5551 |
det |
the,level |
R3737 |
T5551 |
T5549 |
pobj |
level,in |
R3738 |
T5552 |
T5551 |
cc |
and,level |
R3739 |
T5553 |
T5551 |
conj |
extent,level |
R3740 |
T5554 |
T5551 |
prep |
of,level |
R3741 |
T5555 |
T5556 |
compound |
Cre,recombinase |
R3742 |
T5556 |
T5558 |
compound |
recombinase,expression |
R3743 |
T5557 |
T5556 |
punct |
-,recombinase |
R3744 |
T5558 |
T5554 |
pobj |
expression,of |
R3745 |
T5559 |
T5544 |
prep |
in,reflected |
R3746 |
T5560 |
T5559 |
pobj |
forebrain,in |
R3747 |
T5561 |
T5560 |
prep |
of,forebrain |
R3748 |
T5562 |
T5563 |
amod |
transgenic,mice |
R3749 |
T5563 |
T5561 |
pobj |
mice,of |
R3750 |
T5564 |
T5563 |
compound |
TgCre4,mice |
R3751 |
T5565 |
T5544 |
punct |
", ",reflected |
R3752 |
T5566 |
T5567 |
mark |
as,visualized |
R3753 |
T5567 |
T5544 |
advcl |
visualized,reflected |
R3754 |
T5568 |
T5567 |
prep |
by,visualized |
R3755 |
T5569 |
T5570 |
compound |
Cre,activity |
R3756 |
T5570 |
T5568 |
pobj |
activity,by |
R3757 |
T5571 |
T5570 |
punct |
-,activity |
R3758 |
T5572 |
T5567 |
prep |
in,visualized |
R3759 |
T5573 |
T5574 |
det |
the,line |
R3760 |
T5574 |
T5572 |
pobj |
line,in |
R3761 |
T5575 |
T5576 |
compound |
Cre,indicator |
R3762 |
T5576 |
T5574 |
compound |
indicator,line |
R3763 |
T5577 |
T5576 |
punct |
-,indicator |
R3764 |
T5578 |
T5574 |
compound |
mouse,line |
R3765 |
T5579 |
T5574 |
appos |
R26R,line |
R3766 |
T5580 |
T5544 |
punct |
.,reflected |
R3767 |
T5582 |
T5583 |
nsubj |
We,observed |
R3768 |
T5584 |
T5585 |
mark |
that,varied |
R3770 |
T5586 |
T5585 |
nsubj |
onset,varied |
R3771 |
T5587 |
T5586 |
cc |
and,onset |
R3772 |
T5588 |
T5586 |
conj |
extent,onset |
R3773 |
T5589 |
T5586 |
prep |
of,onset |
R3774 |
T5590 |
T5591 |
compound |
Cre,recombinase |
R3775 |
T5591 |
T5593 |
compound |
recombinase,expression |
R3776 |
T5592 |
T5591 |
punct |
-,recombinase |
R3777 |
T5593 |
T5589 |
pobj |
expression,of |
R3778 |
T5594 |
T5593 |
prep |
in,expression |
R3779 |
T5595 |
T5596 |
amod |
different,regions |
R3780 |
T5596 |
T5594 |
pobj |
regions,in |
R3781 |
T5597 |
T5596 |
compound |
forebrain,regions |
R3782 |
T5598 |
T5585 |
prep |
among,varied |
R3783 |
T5599 |
T5600 |
amod |
individual,mice |
R3784 |
T5600 |
T5598 |
pobj |
mice,among |
R3785 |
T5601 |
T5600 |
compound |
TgCre4,mice |
R3786 |
T5602 |
T5603 |
punct |
(,3A |
R3787 |
T5603 |
T5585 |
parataxis |
3A,varied |
R3788 |
T5604 |
T5603 |
compound |
Figure,3A |
R3789 |
T5605 |
T5603 |
punct |
),3A |
R3790 |
T5606 |
T5583 |
punct |
", ",observed |
R3791 |
T5607 |
T5608 |
dep |
which,visualized |
R3792 |
T5608 |
T5583 |
advcl |
visualized,observed |
R3793 |
T5609 |
T5608 |
aux |
could,visualized |
R3794 |
T5610 |
T5608 |
advmod |
also,visualized |
R3795 |
T5611 |
T5608 |
auxpass |
be,visualized |
R3796 |
T5612 |
T5608 |
advmod |
directly,visualized |
R3797 |
T5613 |
T5608 |
prep |
by,visualized |
R3798 |
T5614 |
T5613 |
pobj |
immunohistochemistry,by |
R3799 |
T5615 |
T5608 |
prep |
with,visualized |
R3800 |
T5616 |
T5617 |
det |
a,antibody |
R3801 |
T5617 |
T5615 |
pobj |
antibody,with |
R3802 |
T5618 |
T5617 |
compound |
Cre,antibody |
R3803 |
T5619 |
T5617 |
punct |
-,antibody |
R3804 |
T5620 |
T5621 |
punct |
(,data |
R3805 |
T5621 |
T5583 |
meta |
data,observed |
R3806 |
T5622 |
T5621 |
amod |
unpublished,data |
R3807 |
T5623 |
T5621 |
punct |
),data |
R3808 |
T5624 |
T5583 |
punct |
.,observed |
R3809 |
T5626 |
T5627 |
mark |
As,persisted |
R3810 |
T5627 |
T5630 |
advcl |
persisted,attributed |
R3811 |
T5628 |
T5629 |
det |
this,variability |
R3812 |
T5629 |
T5627 |
nsubj |
variability,persisted |
R3813 |
T5631 |
T5627 |
prep |
after,persisted |
R3814 |
T5632 |
T5633 |
amod |
several,backcrosses |
R3815 |
T5633 |
T5631 |
pobj |
backcrosses,after |
R3816 |
T5634 |
T5627 |
punct |
", ",persisted |
R3817 |
T5635 |
T5627 |
cc |
and,persisted |
R3818 |
T5636 |
T5637 |
compound |
Southern,blot |
R3819 |
T5637 |
T5638 |
compound |
blot,analysis |
R3820 |
T5638 |
T5639 |
nsubj |
analysis,revealed |
R3821 |
T5639 |
T5627 |
conj |
revealed,persisted |
R3822 |
T5640 |
T5641 |
det |
no,differences |
R3823 |
T5641 |
T5639 |
dobj |
differences,revealed |
R3824 |
T5642 |
T5641 |
prep |
of,differences |
R3825 |
T5643 |
T5644 |
compound |
transgene,integration |
R3826 |
T5644 |
T5642 |
pobj |
integration,of |
R3827 |
T5645 |
T5644 |
cc |
or,integration |
R3828 |
T5646 |
T5644 |
conj |
number,integration |
R3829 |
T5647 |
T5641 |
prep |
among,differences |
R3830 |
T5648 |
T5647 |
pobj |
animals,among |
R3831 |
T5649 |
T5650 |
punct |
(,3B |
R3832 |
T5650 |
T5639 |
parataxis |
3B,revealed |
R3833 |
T5651 |
T5650 |
compound |
Figure,3B |
R3834 |
T5652 |
T5650 |
punct |
),3B |
R3835 |
T5653 |
T5630 |
punct |
", ",attributed |
R3836 |
T5654 |
T5630 |
nsubjpass |
it,attributed |
R3837 |
T5655 |
T5630 |
aux |
could,attributed |
R3838 |
T5656 |
T5630 |
neg |
not,attributed |
R3839 |
T5657 |
T5630 |
auxpass |
be,attributed |
R3840 |
T5658 |
T5630 |
prep |
to,attributed |
R3841 |
T5659 |
T5660 |
amod |
genetic,differences |
R3842 |
T5660 |
T5658 |
pobj |
differences,to |
R3843 |
T5661 |
T5658 |
cc |
but,to |
R3844 |
T5662 |
T5661 |
advmod |
rather,but |
R3845 |
T5663 |
T5658 |
conj |
to,to |
R3846 |
T5664 |
T5665 |
amod |
epigenetic,mechanisms |
R3847 |
T5665 |
T5663 |
pobj |
mechanisms,to |
R3848 |
T5666 |
T5630 |
punct |
.,attributed |
R3769 |
T5585 |
T5583 |
ccomp |
varied,observed |