Id |
Subject |
Object |
Predicate |
Lexical cue |
T5171 |
0-9 |
JJ |
denotes |
Olfactory |
T5172 |
10-16 |
NN |
denotes |
Memory |
T5173 |
17-19 |
VBZ |
denotes |
Is |
T5174 |
20-33 |
RB |
denotes |
Significantly |
T5175 |
34-43 |
VBN |
denotes |
Decreased |
T5176 |
44-47 |
CC |
denotes |
but |
T5177 |
48-54 |
RB |
denotes |
Highly |
T5178 |
55-63 |
JJ |
denotes |
Variable |
T5179 |
64-66 |
IN |
denotes |
in |
T5180 |
67-71 |
NN |
denotes |
GluR |
T5181 |
72-76 |
NN |
denotes |
BΔFB |
T5182 |
71-72 |
HYPH |
denotes |
- |
T5183 |
77-81 |
NNS |
denotes |
Mice |
T5184 |
81-243 |
sentence |
denotes |
To capture the full extent of the role of Ca2+-permeable AMPARs in olfactory behavior, we next assessed the effects of altered AMPA channels on olfactory memory. |
T5185 |
82-84 |
TO |
denotes |
To |
T5186 |
85-92 |
VB |
denotes |
capture |
T5187 |
177-185 |
VBD |
denotes |
assessed |
T5188 |
93-96 |
DT |
denotes |
the |
T5189 |
102-108 |
NN |
denotes |
extent |
T5190 |
97-101 |
JJ |
denotes |
full |
T5191 |
109-111 |
IN |
denotes |
of |
T5192 |
112-115 |
DT |
denotes |
the |
T5193 |
116-120 |
NN |
denotes |
role |
T5194 |
121-123 |
IN |
denotes |
of |
T5195 |
124-127 |
NN |
denotes |
Ca2 |
T5196 |
129-138 |
JJ |
denotes |
permeable |
T5197 |
127-128 |
SYM |
denotes |
+ |
T5198 |
128-129 |
HYPH |
denotes |
- |
T5199 |
139-145 |
NNS |
denotes |
AMPARs |
T5200 |
146-148 |
IN |
denotes |
in |
T5201 |
149-158 |
JJ |
denotes |
olfactory |
T5202 |
159-167 |
NN |
denotes |
behavior |
T5203 |
167-169 |
, |
denotes |
, |
T5204 |
169-171 |
PRP |
denotes |
we |
T5205 |
172-176 |
RB |
denotes |
next |
T5206 |
186-189 |
DT |
denotes |
the |
T5207 |
190-197 |
NNS |
denotes |
effects |
T5208 |
198-200 |
IN |
denotes |
of |
T5209 |
201-208 |
VBN |
denotes |
altered |
T5210 |
214-222 |
NNS |
denotes |
channels |
T5211 |
209-213 |
NN |
denotes |
AMPA |
T5212 |
223-225 |
IN |
denotes |
on |
T5213 |
226-235 |
JJ |
denotes |
olfactory |
T5214 |
236-242 |
NN |
denotes |
memory |
T5215 |
242-243 |
. |
denotes |
. |
T5216 |
243-601 |
sentence |
denotes |
To probe olfactory memory in GluR-BΔFB mice, six days after the end of the first training phase for odor discrimination (amylacetate versus ethylbutyrate), the training trials for the third odor pair (pelargonic versus valeric acid) were interleaved with unrewarded trials in which amylacetate or ethylbutyrate were again presented (black bar in Figure 2C). |
T5217 |
244-246 |
TO |
denotes |
To |
T5218 |
247-252 |
VB |
denotes |
probe |
T5219 |
482-493 |
VBN |
denotes |
interleaved |
T5220 |
253-262 |
JJ |
denotes |
olfactory |
T5221 |
263-269 |
NN |
denotes |
memory |
T5222 |
270-272 |
IN |
denotes |
in |
T5223 |
273-277 |
NN |
denotes |
GluR |
T5224 |
278-282 |
NN |
denotes |
BΔFB |
T5225 |
277-278 |
HYPH |
denotes |
- |
T5226 |
283-287 |
NNS |
denotes |
mice |
T5227 |
287-289 |
, |
denotes |
, |
T5228 |
289-292 |
CD |
denotes |
six |
T5229 |
293-297 |
NNS |
denotes |
days |
T5230 |
298-303 |
IN |
denotes |
after |
T5231 |
304-307 |
DT |
denotes |
the |
T5232 |
308-311 |
NN |
denotes |
end |
T5233 |
312-314 |
IN |
denotes |
of |
T5234 |
315-318 |
DT |
denotes |
the |
T5235 |
334-339 |
NN |
denotes |
phase |
T5236 |
319-324 |
JJ |
denotes |
first |
T5237 |
325-333 |
NN |
denotes |
training |
T5238 |
340-343 |
IN |
denotes |
for |
T5239 |
344-348 |
NN |
denotes |
odor |
T5240 |
349-363 |
NN |
denotes |
discrimination |
T5241 |
364-365 |
-LRB- |
denotes |
( |
T5242 |
365-376 |
NN |
denotes |
amylacetate |
T5243 |
377-383 |
CC |
denotes |
versus |
T5244 |
384-397 |
NN |
denotes |
ethylbutyrate |
T5245 |
397-398 |
-RRB- |
denotes |
) |
T5246 |
398-400 |
, |
denotes |
, |
T5247 |
400-403 |
DT |
denotes |
the |
T5248 |
413-419 |
NNS |
denotes |
trials |
T5249 |
404-412 |
NN |
denotes |
training |
T5250 |
420-423 |
IN |
denotes |
for |
T5251 |
424-427 |
DT |
denotes |
the |
T5252 |
439-443 |
NN |
denotes |
pair |
T5253 |
428-433 |
JJ |
denotes |
third |
T5254 |
434-438 |
NN |
denotes |
odor |
T5255 |
444-445 |
-LRB- |
denotes |
( |
T5256 |
445-455 |
JJ |
denotes |
pelargonic |
T5257 |
471-475 |
NN |
denotes |
acid |
T5258 |
456-462 |
CC |
denotes |
versus |
T5259 |
463-470 |
JJ |
denotes |
valeric |
T5260 |
475-476 |
-RRB- |
denotes |
) |
T5261 |
477-481 |
VBD |
denotes |
were |
T5262 |
494-498 |
IN |
denotes |
with |
T5263 |
499-509 |
JJ |
denotes |
unrewarded |
T5264 |
510-516 |
NNS |
denotes |
trials |
T5265 |
517-519 |
IN |
denotes |
in |
T5266 |
566-575 |
VBN |
denotes |
presented |
T5267 |
520-525 |
WDT |
denotes |
which |
T5268 |
526-537 |
NN |
denotes |
amylacetate |
T5269 |
538-540 |
CC |
denotes |
or |
T5270 |
541-554 |
NN |
denotes |
ethylbutyrate |
T5271 |
555-559 |
VBD |
denotes |
were |
T5272 |
560-565 |
RB |
denotes |
again |
T5273 |
576-577 |
-LRB- |
denotes |
( |
T5274 |
583-586 |
NN |
denotes |
bar |
T5275 |
577-582 |
JJ |
denotes |
black |
T5276 |
587-589 |
IN |
denotes |
in |
T5277 |
590-596 |
NN |
denotes |
Figure |
T5278 |
597-599 |
NN |
denotes |
2C |
T5279 |
599-600 |
-RRB- |
denotes |
) |
T5280 |
600-601 |
. |
denotes |
. |
T5281 |
601-818 |
sentence |
denotes |
Whereas control mice reliably responded only to the previously rewarded odor (memory of 86 ± 8%, mean ± SD, n = 9, Figure 2E), GluR-BΔFB mice showed reduced olfactory memory (69 ± 16%, n = 9, p < 0.05, Mann-Whitney). |
T5282 |
602-609 |
IN |
denotes |
Whereas |
T5283 |
632-641 |
VBD |
denotes |
responded |
T5284 |
610-617 |
NN |
denotes |
control |
T5285 |
618-622 |
NNS |
denotes |
mice |
T5286 |
623-631 |
RB |
denotes |
reliably |
T5287 |
744-750 |
VBD |
denotes |
showed |
T5288 |
642-646 |
RB |
denotes |
only |
T5289 |
647-649 |
IN |
denotes |
to |
T5290 |
650-653 |
DT |
denotes |
the |
T5291 |
674-678 |
NN |
denotes |
odor |
T5292 |
654-664 |
RB |
denotes |
previously |
T5293 |
665-673 |
VBN |
denotes |
rewarded |
T5294 |
679-680 |
-LRB- |
denotes |
( |
T5295 |
724-726 |
NN |
denotes |
2E |
T5296 |
680-686 |
NN |
denotes |
memory |
T5297 |
687-689 |
IN |
denotes |
of |
T5298 |
690-692 |
CD |
denotes |
86 |
T5299 |
695-696 |
CD |
denotes |
8 |
T5300 |
693-694 |
SYM |
denotes |
± |
T5301 |
696-697 |
NN |
denotes |
% |
T5302 |
697-699 |
, |
denotes |
, |
T5303 |
699-703 |
NN |
denotes |
mean |
T5304 |
706-708 |
NN |
denotes |
SD |
T5305 |
704-705 |
SYM |
denotes |
± |
T5306 |
708-710 |
, |
denotes |
, |
T5307 |
710-711 |
NN |
denotes |
n |
T5308 |
714-715 |
CD |
denotes |
9 |
T5309 |
712-713 |
SYM |
denotes |
= |
T5310 |
715-717 |
, |
denotes |
, |
T5311 |
717-723 |
NN |
denotes |
Figure |
T5312 |
726-727 |
-RRB- |
denotes |
) |
T5313 |
727-729 |
, |
denotes |
, |
T5314 |
729-733 |
NN |
denotes |
GluR |
T5315 |
734-738 |
NN |
denotes |
BΔFB |
T5316 |
733-734 |
HYPH |
denotes |
- |
T5317 |
739-743 |
NNS |
denotes |
mice |
T5318 |
751-758 |
VBN |
denotes |
reduced |
T5319 |
769-775 |
NN |
denotes |
memory |
T5320 |
759-768 |
JJ |
denotes |
olfactory |
T5321 |
776-777 |
-LRB- |
denotes |
( |
T5322 |
809-816 |
NNP |
denotes |
Whitney |
T5323 |
777-779 |
CD |
denotes |
69 |
T5324 |
782-784 |
CD |
denotes |
16 |
T5325 |
780-781 |
SYM |
denotes |
± |
T5326 |
784-785 |
NN |
denotes |
% |
T5327 |
785-787 |
, |
denotes |
, |
T5328 |
787-788 |
NN |
denotes |
n |
T5329 |
791-792 |
CD |
denotes |
9 |
T5330 |
789-790 |
SYM |
denotes |
= |
T5331 |
792-794 |
, |
denotes |
, |
T5332 |
794-795 |
NN |
denotes |
p |
T5333 |
798-802 |
CD |
denotes |
0.05 |
T5334 |
796-797 |
SYM |
denotes |
< |
T5335 |
802-804 |
, |
denotes |
, |
T5336 |
804-808 |
NNP |
denotes |
Mann |
T5337 |
808-809 |
HYPH |
denotes |
- |
T5338 |
816-817 |
-RRB- |
denotes |
) |
T5339 |
817-818 |
. |
denotes |
. |
T5340 |
818-971 |
sentence |
denotes |
Due to the more rapid learning observed in GluR-BΔFB, one could speculate that a decrease in olfactory memory might simply reflect increased extinction. |
T5341 |
819-822 |
IN |
denotes |
Due |
T5342 |
883-892 |
VB |
denotes |
speculate |
T5343 |
823-825 |
IN |
denotes |
to |
T5344 |
826-829 |
DT |
denotes |
the |
T5345 |
841-849 |
NN |
denotes |
learning |
T5346 |
830-834 |
RBR |
denotes |
more |
T5347 |
835-840 |
JJ |
denotes |
rapid |
T5348 |
850-858 |
VBN |
denotes |
observed |
T5349 |
859-861 |
IN |
denotes |
in |
T5350 |
862-866 |
NN |
denotes |
GluR |
T5351 |
867-871 |
NN |
denotes |
BΔFB |
T5352 |
866-867 |
HYPH |
denotes |
- |
T5353 |
871-873 |
, |
denotes |
, |
T5354 |
873-876 |
PRP |
denotes |
one |
T5355 |
877-882 |
MD |
denotes |
could |
T5356 |
893-897 |
IN |
denotes |
that |
T5357 |
942-949 |
VB |
denotes |
reflect |
T5358 |
898-899 |
DT |
denotes |
a |
T5359 |
900-908 |
NN |
denotes |
decrease |
T5360 |
909-911 |
IN |
denotes |
in |
T5361 |
912-921 |
JJ |
denotes |
olfactory |
T5362 |
922-928 |
NN |
denotes |
memory |
T5363 |
929-934 |
MD |
denotes |
might |
T5364 |
935-941 |
RB |
denotes |
simply |
T5365 |
950-959 |
VBN |
denotes |
increased |
T5366 |
960-970 |
NN |
denotes |
extinction |
T5367 |
970-971 |
. |
denotes |
. |
T5368 |
971-1244 |
sentence |
denotes |
However, extinction levels were low in general, no significant group-trial interaction could be found for the memory trials (2-way ANOVA, F(6,90) = 1.5, p > 0.1), and a restriction of the analysis to early memory trials displayed essentially the same pattern (Figure S3A). |
T5369 |
972-979 |
RB |
denotes |
However |
T5370 |
999-1003 |
VBD |
denotes |
were |
T5371 |
979-981 |
, |
denotes |
, |
T5372 |
981-991 |
NN |
denotes |
extinction |
T5373 |
992-998 |
NNS |
denotes |
levels |
T5374 |
1004-1007 |
JJ |
denotes |
low |
T5375 |
1008-1010 |
IN |
denotes |
in |
T5376 |
1011-1018 |
JJ |
denotes |
general |
T5377 |
1018-1020 |
, |
denotes |
, |
T5378 |
1020-1022 |
DT |
denotes |
no |
T5379 |
1047-1058 |
NN |
denotes |
interaction |
T5380 |
1023-1034 |
JJ |
denotes |
significant |
T5381 |
1035-1040 |
NN |
denotes |
group |
T5382 |
1041-1046 |
NN |
denotes |
trial |
T5383 |
1040-1041 |
SYM |
denotes |
- |
T5384 |
1068-1073 |
VBN |
denotes |
found |
T5385 |
1059-1064 |
MD |
denotes |
could |
T5386 |
1065-1067 |
VB |
denotes |
be |
T5387 |
1074-1077 |
IN |
denotes |
for |
T5388 |
1078-1081 |
DT |
denotes |
the |
T5389 |
1089-1095 |
NNS |
denotes |
trials |
T5390 |
1082-1088 |
NN |
denotes |
memory |
T5391 |
1096-1097 |
-LRB- |
denotes |
( |
T5392 |
1103-1108 |
NN |
denotes |
ANOVA |
T5393 |
1097-1098 |
CD |
denotes |
2 |
T5394 |
1099-1102 |
NN |
denotes |
way |
T5395 |
1098-1099 |
HYPH |
denotes |
- |
T5396 |
1108-1110 |
, |
denotes |
, |
T5397 |
1110-1111 |
NN |
denotes |
F |
T5398 |
1120-1123 |
CD |
denotes |
1.5 |
T5399 |
1111-1112 |
-LRB- |
denotes |
( |
T5400 |
1112-1113 |
CD |
denotes |
6 |
T5401 |
1113-1114 |
, |
denotes |
, |
T5402 |
1114-1116 |
CD |
denotes |
90 |
T5403 |
1116-1117 |
-RRB- |
denotes |
) |
T5404 |
1118-1119 |
SYM |
denotes |
= |
T5405 |
1123-1125 |
, |
denotes |
, |
T5406 |
1125-1126 |
NN |
denotes |
p |
T5407 |
1129-1132 |
CD |
denotes |
0.1 |
T5408 |
1127-1128 |
SYM |
denotes |
> |
T5409 |
1132-1133 |
-RRB- |
denotes |
) |
T5410 |
1133-1135 |
, |
denotes |
, |
T5411 |
1135-1138 |
CC |
denotes |
and |
T5412 |
1139-1140 |
DT |
denotes |
a |
T5413 |
1141-1152 |
NN |
denotes |
restriction |
T5414 |
1192-1201 |
VBD |
denotes |
displayed |
T5415 |
1153-1155 |
IN |
denotes |
of |
T5416 |
1156-1159 |
DT |
denotes |
the |
T5417 |
1160-1168 |
NN |
denotes |
analysis |
T5418 |
1169-1171 |
IN |
denotes |
to |
T5419 |
1172-1177 |
JJ |
denotes |
early |
T5420 |
1185-1191 |
NNS |
denotes |
trials |
T5421 |
1178-1184 |
NN |
denotes |
memory |
T5422 |
1202-1213 |
RB |
denotes |
essentially |
T5423 |
1223-1230 |
NN |
denotes |
pattern |
T5424 |
1214-1217 |
DT |
denotes |
the |
T5425 |
1218-1222 |
JJ |
denotes |
same |
T5426 |
1231-1232 |
-LRB- |
denotes |
( |
T5427 |
1239-1242 |
NN |
denotes |
S3A |
T5428 |
1232-1238 |
NN |
denotes |
Figure |
T5429 |
1242-1243 |
-RRB- |
denotes |
) |
T5430 |
1243-1244 |
. |
denotes |
. |
T5431 |
1244-1365 |
sentence |
denotes |
Thus, reduced performance in the probe trials is not due to increased extinction but reflects genuine memory impairment. |
T5432 |
1245-1249 |
RB |
denotes |
Thus |
T5433 |
1291-1293 |
VBZ |
denotes |
is |
T5434 |
1249-1251 |
, |
denotes |
, |
T5435 |
1251-1258 |
VBN |
denotes |
reduced |
T5436 |
1259-1270 |
NN |
denotes |
performance |
T5437 |
1271-1273 |
IN |
denotes |
in |
T5438 |
1274-1277 |
DT |
denotes |
the |
T5439 |
1284-1290 |
NNS |
denotes |
trials |
T5440 |
1278-1283 |
NN |
denotes |
probe |
T5441 |
1294-1297 |
RB |
denotes |
not |
T5442 |
1298-1301 |
IN |
denotes |
due |
T5443 |
1302-1304 |
IN |
denotes |
to |
T5444 |
1305-1314 |
VBN |
denotes |
increased |
T5445 |
1315-1325 |
NN |
denotes |
extinction |
T5446 |
1326-1329 |
CC |
denotes |
but |
T5447 |
1330-1338 |
VBZ |
denotes |
reflects |
T5448 |
1339-1346 |
JJ |
denotes |
genuine |
T5449 |
1354-1364 |
NN |
denotes |
impairment |
T5450 |
1347-1353 |
NN |
denotes |
memory |
T5451 |
1364-1365 |
. |
denotes |
. |
T5452 |
1365-1632 |
sentence |
denotes |
Moreover, because the hippocampus-dependent spatial memory after-task acquisition in the Y-maze was not affected (Figure S2), we conclude that the observed olfactory memory deficit is rather specific for olfaction and does not readily generalize to other modalities. |
T5453 |
1366-1374 |
RB |
denotes |
Moreover |
T5454 |
1495-1503 |
VBP |
denotes |
conclude |
T5455 |
1374-1376 |
, |
denotes |
, |
T5456 |
1376-1383 |
IN |
denotes |
because |
T5457 |
1470-1478 |
VBN |
denotes |
affected |
T5458 |
1384-1387 |
DT |
denotes |
the |
T5459 |
1436-1447 |
NN |
denotes |
acquisition |
T5460 |
1388-1399 |
NN |
denotes |
hippocampus |
T5461 |
1400-1409 |
JJ |
denotes |
dependent |
T5462 |
1399-1400 |
HYPH |
denotes |
- |
T5463 |
1410-1417 |
JJ |
denotes |
spatial |
T5464 |
1418-1424 |
NN |
denotes |
memory |
T5465 |
1425-1430 |
IN |
denotes |
after |
T5466 |
1431-1435 |
NN |
denotes |
task |
T5467 |
1430-1431 |
HYPH |
denotes |
- |
T5468 |
1448-1450 |
IN |
denotes |
in |
T5469 |
1451-1454 |
DT |
denotes |
the |
T5470 |
1457-1461 |
NN |
denotes |
maze |
T5471 |
1455-1456 |
NN |
denotes |
Y |
T5472 |
1456-1457 |
HYPH |
denotes |
- |
T5473 |
1462-1465 |
VBD |
denotes |
was |
T5474 |
1466-1469 |
RB |
denotes |
not |
T5475 |
1479-1480 |
-LRB- |
denotes |
( |
T5476 |
1487-1489 |
NN |
denotes |
S2 |
T5477 |
1480-1486 |
NN |
denotes |
Figure |
T5478 |
1489-1490 |
-RRB- |
denotes |
) |
T5479 |
1490-1492 |
, |
denotes |
, |
T5480 |
1492-1494 |
PRP |
denotes |
we |
T5481 |
1504-1508 |
IN |
denotes |
that |
T5482 |
1547-1549 |
VBZ |
denotes |
is |
T5483 |
1509-1512 |
DT |
denotes |
the |
T5484 |
1539-1546 |
NN |
denotes |
deficit |
T5485 |
1513-1521 |
VBN |
denotes |
observed |
T5486 |
1522-1531 |
JJ |
denotes |
olfactory |
T5487 |
1532-1538 |
NN |
denotes |
memory |
T5488 |
1550-1556 |
RB |
denotes |
rather |
T5489 |
1557-1565 |
JJ |
denotes |
specific |
T5490 |
1566-1569 |
IN |
denotes |
for |
T5491 |
1570-1579 |
NN |
denotes |
olfaction |
T5492 |
1580-1583 |
CC |
denotes |
and |
T5493 |
1584-1588 |
VBZ |
denotes |
does |
T5494 |
1601-1611 |
VB |
denotes |
generalize |
T5495 |
1589-1592 |
RB |
denotes |
not |
T5496 |
1593-1600 |
RB |
denotes |
readily |
T5497 |
1612-1614 |
IN |
denotes |
to |
T5498 |
1615-1620 |
JJ |
denotes |
other |
T5499 |
1621-1631 |
NNS |
denotes |
modalities |
T5500 |
1631-1632 |
. |
denotes |
. |
T5501 |
1632-1890 |
sentence |
denotes |
While the improved odor discrimination and learning behavior showed only little variability, the significantly impaired memory performance observed in GluR-BΔFB mice was highly variable among individual animals compared with control littermates (Figure 2E). |
T5502 |
1633-1638 |
IN |
denotes |
While |
T5503 |
1694-1700 |
VBD |
denotes |
showed |
T5504 |
1639-1642 |
DT |
denotes |
the |
T5505 |
1685-1693 |
NN |
denotes |
behavior |
T5506 |
1643-1651 |
VBN |
denotes |
improved |
T5507 |
1652-1656 |
NN |
denotes |
odor |
T5508 |
1657-1671 |
NN |
denotes |
discrimination |
T5509 |
1672-1675 |
CC |
denotes |
and |
T5510 |
1676-1684 |
NN |
denotes |
learning |
T5511 |
1799-1802 |
VBD |
denotes |
was |
T5512 |
1701-1705 |
RB |
denotes |
only |
T5513 |
1713-1724 |
NN |
denotes |
variability |
T5514 |
1706-1712 |
JJ |
denotes |
little |
T5515 |
1724-1726 |
, |
denotes |
, |
T5516 |
1726-1729 |
DT |
denotes |
the |
T5517 |
1760-1771 |
NN |
denotes |
performance |
T5518 |
1730-1743 |
RB |
denotes |
significantly |
T5519 |
1744-1752 |
VBN |
denotes |
impaired |
T5520 |
1753-1759 |
NN |
denotes |
memory |
T5521 |
1772-1780 |
VBN |
denotes |
observed |
T5522 |
1781-1783 |
IN |
denotes |
in |
T5523 |
1784-1788 |
NN |
denotes |
GluR |
T5524 |
1789-1793 |
NN |
denotes |
BΔFB |
T5525 |
1788-1789 |
HYPH |
denotes |
- |
T5526 |
1794-1798 |
NNS |
denotes |
mice |
T5527 |
1803-1809 |
RB |
denotes |
highly |
T5528 |
1810-1818 |
JJ |
denotes |
variable |
T5529 |
1819-1824 |
IN |
denotes |
among |
T5530 |
1825-1835 |
JJ |
denotes |
individual |
T5531 |
1836-1843 |
NNS |
denotes |
animals |
T5532 |
1844-1852 |
VBN |
denotes |
compared |
T5533 |
1853-1857 |
IN |
denotes |
with |
T5534 |
1858-1865 |
NN |
denotes |
control |
T5535 |
1866-1877 |
NNS |
denotes |
littermates |
T5536 |
1878-1879 |
-LRB- |
denotes |
( |
T5537 |
1886-1888 |
NN |
denotes |
2E |
T5538 |
1879-1885 |
NN |
denotes |
Figure |
T5539 |
1888-1889 |
-RRB- |
denotes |
) |
T5540 |
1889-1890 |
. |
denotes |
. |
T5541 |
1890-2103 |
sentence |
denotes |
This variability in olfactory memory was reflected in the level and extent of Cre-recombinase expression in forebrain of transgenic TgCre4 mice, as visualized by Cre-activity in the Cre-indicator mouse line R26R. |
T5542 |
1891-1895 |
DT |
denotes |
This |
T5543 |
1896-1907 |
NN |
denotes |
variability |
T5544 |
1932-1941 |
VBN |
denotes |
reflected |
T5545 |
1908-1910 |
IN |
denotes |
in |
T5546 |
1911-1920 |
JJ |
denotes |
olfactory |
T5547 |
1921-1927 |
NN |
denotes |
memory |
T5548 |
1928-1931 |
VBD |
denotes |
was |
T5549 |
1942-1944 |
IN |
denotes |
in |
T5550 |
1945-1948 |
DT |
denotes |
the |
T5551 |
1949-1954 |
NN |
denotes |
level |
T5552 |
1955-1958 |
CC |
denotes |
and |
T5553 |
1959-1965 |
NN |
denotes |
extent |
T5554 |
1966-1968 |
IN |
denotes |
of |
T5555 |
1969-1972 |
NN |
denotes |
Cre |
T5556 |
1973-1984 |
NN |
denotes |
recombinase |
T5557 |
1972-1973 |
HYPH |
denotes |
- |
T5558 |
1985-1995 |
NN |
denotes |
expression |
T5559 |
1996-1998 |
IN |
denotes |
in |
T5560 |
1999-2008 |
NN |
denotes |
forebrain |
T5561 |
2009-2011 |
IN |
denotes |
of |
T5562 |
2012-2022 |
JJ |
denotes |
transgenic |
T5563 |
2030-2034 |
NNS |
denotes |
mice |
T5564 |
2023-2029 |
NN |
denotes |
TgCre4 |
T5565 |
2034-2036 |
, |
denotes |
, |
T5566 |
2036-2038 |
IN |
denotes |
as |
T5567 |
2039-2049 |
VBN |
denotes |
visualized |
T5568 |
2050-2052 |
IN |
denotes |
by |
T5569 |
2053-2056 |
NN |
denotes |
Cre |
T5570 |
2057-2065 |
NN |
denotes |
activity |
T5571 |
2056-2057 |
HYPH |
denotes |
- |
T5572 |
2066-2068 |
IN |
denotes |
in |
T5573 |
2069-2072 |
DT |
denotes |
the |
T5574 |
2093-2097 |
NN |
denotes |
line |
T5575 |
2073-2076 |
NN |
denotes |
Cre |
T5576 |
2077-2086 |
NN |
denotes |
indicator |
T5577 |
2076-2077 |
HYPH |
denotes |
- |
T5578 |
2087-2092 |
NN |
denotes |
mouse |
T5579 |
2098-2102 |
NN |
denotes |
R26R |
T5580 |
2102-2103 |
. |
denotes |
. |
T5581 |
2103-2351 |
sentence |
denotes |
We observed that onset and extent of Cre-recombinase expression in different forebrain regions varied among individual TgCre4 mice (Figure 3A), which could also be directly visualized by immunohistochemistry with a Cre-antibody (unpublished data). |
T5582 |
2104-2106 |
PRP |
denotes |
We |
T5583 |
2107-2115 |
VBD |
denotes |
observed |
T5584 |
2116-2120 |
IN |
denotes |
that |
T5585 |
2199-2205 |
VBD |
denotes |
varied |
T5586 |
2121-2126 |
NN |
denotes |
onset |
T5587 |
2127-2130 |
CC |
denotes |
and |
T5588 |
2131-2137 |
NN |
denotes |
extent |
T5589 |
2138-2140 |
IN |
denotes |
of |
T5590 |
2141-2144 |
NN |
denotes |
Cre |
T5591 |
2145-2156 |
NN |
denotes |
recombinase |
T5592 |
2144-2145 |
HYPH |
denotes |
- |
T5593 |
2157-2167 |
NN |
denotes |
expression |
T5594 |
2168-2170 |
IN |
denotes |
in |
T5595 |
2171-2180 |
JJ |
denotes |
different |
T5596 |
2191-2198 |
NNS |
denotes |
regions |
T5597 |
2181-2190 |
NN |
denotes |
forebrain |
T5598 |
2206-2211 |
IN |
denotes |
among |
T5599 |
2212-2222 |
JJ |
denotes |
individual |
T5600 |
2230-2234 |
NNS |
denotes |
mice |
T5601 |
2223-2229 |
NN |
denotes |
TgCre4 |
T5602 |
2235-2236 |
-LRB- |
denotes |
( |
T5603 |
2243-2245 |
NN |
denotes |
3A |
T5604 |
2236-2242 |
NN |
denotes |
Figure |
T5605 |
2245-2246 |
-RRB- |
denotes |
) |
T5606 |
2246-2248 |
, |
denotes |
, |
T5607 |
2248-2253 |
WDT |
denotes |
which |
T5608 |
2277-2287 |
VBN |
denotes |
visualized |
T5609 |
2254-2259 |
MD |
denotes |
could |
T5610 |
2260-2264 |
RB |
denotes |
also |
T5611 |
2265-2267 |
VB |
denotes |
be |
T5612 |
2268-2276 |
RB |
denotes |
directly |
T5613 |
2288-2290 |
IN |
denotes |
by |
T5614 |
2291-2311 |
NN |
denotes |
immunohistochemistry |
T5615 |
2312-2316 |
IN |
denotes |
with |
T5616 |
2317-2318 |
DT |
denotes |
a |
T5617 |
2323-2331 |
NN |
denotes |
antibody |
T5618 |
2319-2322 |
NN |
denotes |
Cre |
T5619 |
2322-2323 |
HYPH |
denotes |
- |
T5620 |
2332-2333 |
-LRB- |
denotes |
( |
T5621 |
2345-2349 |
NNS |
denotes |
data |
T5622 |
2333-2344 |
JJ |
denotes |
unpublished |
T5623 |
2349-2350 |
-RRB- |
denotes |
) |
T5624 |
2350-2351 |
. |
denotes |
. |
T5625 |
2351-2608 |
sentence |
denotes |
As this variability persisted after several backcrosses, and Southern blot analysis revealed no differences of transgene integration or number among animals (Figure 3B), it could not be attributed to genetic differences but rather to epigenetic mechanisms. |
T5626 |
2352-2354 |
IN |
denotes |
As |
T5627 |
2372-2381 |
VBD |
denotes |
persisted |
T5628 |
2355-2359 |
DT |
denotes |
this |
T5629 |
2360-2371 |
NN |
denotes |
variability |
T5630 |
2538-2548 |
VBN |
denotes |
attributed |
T5631 |
2382-2387 |
IN |
denotes |
after |
T5632 |
2388-2395 |
JJ |
denotes |
several |
T5633 |
2396-2407 |
NNS |
denotes |
backcrosses |
T5634 |
2407-2409 |
, |
denotes |
, |
T5635 |
2409-2412 |
CC |
denotes |
and |
T5636 |
2413-2421 |
NNP |
denotes |
Southern |
T5637 |
2422-2426 |
NN |
denotes |
blot |
T5638 |
2427-2435 |
NN |
denotes |
analysis |
T5639 |
2436-2444 |
VBD |
denotes |
revealed |
T5640 |
2445-2447 |
DT |
denotes |
no |
T5641 |
2448-2459 |
NNS |
denotes |
differences |
T5642 |
2460-2462 |
IN |
denotes |
of |
T5643 |
2463-2472 |
NN |
denotes |
transgene |
T5644 |
2473-2484 |
NN |
denotes |
integration |
T5645 |
2485-2487 |
CC |
denotes |
or |
T5646 |
2488-2494 |
NN |
denotes |
number |
T5647 |
2495-2500 |
IN |
denotes |
among |
T5648 |
2501-2508 |
NNS |
denotes |
animals |
T5649 |
2509-2510 |
-LRB- |
denotes |
( |
T5650 |
2517-2519 |
NN |
denotes |
3B |
T5651 |
2510-2516 |
NN |
denotes |
Figure |
T5652 |
2519-2520 |
-RRB- |
denotes |
) |
T5653 |
2520-2522 |
, |
denotes |
, |
T5654 |
2522-2524 |
PRP |
denotes |
it |
T5655 |
2525-2530 |
MD |
denotes |
could |
T5656 |
2531-2534 |
RB |
denotes |
not |
T5657 |
2535-2537 |
VB |
denotes |
be |
T5658 |
2549-2551 |
IN |
denotes |
to |
T5659 |
2552-2559 |
JJ |
denotes |
genetic |
T5660 |
2560-2571 |
NNS |
denotes |
differences |
T5661 |
2572-2575 |
CC |
denotes |
but |
T5662 |
2576-2582 |
RB |
denotes |
rather |
T5663 |
2583-2585 |
IN |
denotes |
to |
T5664 |
2586-2596 |
JJ |
denotes |
epigenetic |
T5665 |
2597-2607 |
NNS |
denotes |
mechanisms |
T5666 |
2607-2608 |
. |
denotes |
. |
T5667 |
2608-3303 |
sentence |
denotes |
Figure 3 Variability of Cre Expression of Mouse Line TgCre4
(A) Variable Cre expression in forebrains of three different mice positive for TgCre4 and R26R Cre indicator (see Figure S1) at postnatal day 12 pictured by the Cre-dependent β-galactosidase activity (blue, X-gal, counterstain by eosin) in coronal brain slices. Scale bar: 1.25 mm.
(B) Southern blot analysis of BglII-digested genomic mouse DNA of four TgCre4 mice that differed in the Cre expression pattern. Southern probe detects the wild-type (4.5 kbp) and the transgenic (7, 5, 3, and 2 kbp) alleles. Hence, we hypothesized that the variability in olfactory memory reflected the mosaicism observed in the transgenic TgCre4 line. |
T5668 |
3176-3181 |
RB |
denotes |
Hence |
T5669 |
3186-3198 |
VBD |
denotes |
hypothesized |
T5670 |
3181-3183 |
, |
denotes |
, |
T5671 |
3183-3185 |
PRP |
denotes |
we |
T5672 |
3199-3203 |
IN |
denotes |
that |
T5673 |
3240-3249 |
VBD |
denotes |
reflected |
T5674 |
3204-3207 |
DT |
denotes |
the |
T5675 |
3208-3219 |
NN |
denotes |
variability |
T5676 |
3220-3222 |
IN |
denotes |
in |
T5677 |
3223-3232 |
JJ |
denotes |
olfactory |
T5678 |
3233-3239 |
NN |
denotes |
memory |
T5679 |
3250-3253 |
DT |
denotes |
the |
T5680 |
3254-3263 |
NN |
denotes |
mosaicism |
T5681 |
3264-3272 |
VBN |
denotes |
observed |
T5682 |
3273-3275 |
IN |
denotes |
in |
T5683 |
3276-3279 |
DT |
denotes |
the |
T5684 |
3298-3302 |
NN |
denotes |
line |
T5685 |
3280-3290 |
JJ |
denotes |
transgenic |
T5686 |
3291-3297 |
NN |
denotes |
TgCre4 |
T5687 |
3302-3303 |
. |
denotes |
. |
T5688 |
3303-3500 |
sentence |
denotes |
The evaluation of regional differences in expression pattern of animals with robust and poor olfactory memory could then be applied to identify brain areas responsible for the observed phenotypes. |
T5689 |
3304-3307 |
DT |
denotes |
The |
T5690 |
3308-3318 |
NN |
denotes |
evaluation |
T5691 |
3428-3435 |
VBN |
denotes |
applied |
T5692 |
3319-3321 |
IN |
denotes |
of |
T5693 |
3322-3330 |
JJ |
denotes |
regional |
T5694 |
3331-3342 |
NNS |
denotes |
differences |
T5695 |
3343-3345 |
IN |
denotes |
in |
T5696 |
3346-3356 |
NN |
denotes |
expression |
T5697 |
3357-3364 |
NN |
denotes |
pattern |
T5698 |
3365-3367 |
IN |
denotes |
of |
T5699 |
3368-3375 |
NNS |
denotes |
animals |
T5700 |
3376-3380 |
IN |
denotes |
with |
T5701 |
3381-3387 |
JJ |
denotes |
robust |
T5702 |
3407-3413 |
NN |
denotes |
memory |
T5703 |
3388-3391 |
CC |
denotes |
and |
T5704 |
3392-3396 |
JJ |
denotes |
poor |
T5705 |
3397-3406 |
JJ |
denotes |
olfactory |
T5706 |
3414-3419 |
MD |
denotes |
could |
T5707 |
3420-3424 |
RB |
denotes |
then |
T5708 |
3425-3427 |
VB |
denotes |
be |
T5709 |
3436-3438 |
TO |
denotes |
to |
T5710 |
3439-3447 |
VB |
denotes |
identify |
T5711 |
3448-3453 |
NN |
denotes |
brain |
T5712 |
3454-3459 |
NNS |
denotes |
areas |
T5713 |
3460-3471 |
JJ |
denotes |
responsible |
T5714 |
3472-3475 |
IN |
denotes |
for |
T5715 |
3476-3479 |
DT |
denotes |
the |
T5716 |
3489-3499 |
NNS |
denotes |
phenotypes |
T5717 |
3480-3488 |
VBN |
denotes |
observed |
T5718 |
3499-3500 |
. |
denotes |
. |
R3376 |
T5171 |
T5172 |
amod |
Olfactory,Memory |
R3377 |
T5172 |
T5173 |
nsubj |
Memory,Is |
R3378 |
T5174 |
T5175 |
advmod |
Significantly,Decreased |
R3379 |
T5175 |
T5173 |
acomp |
Decreased,Is |
R3380 |
T5176 |
T5175 |
cc |
but,Decreased |
R3381 |
T5177 |
T5178 |
advmod |
Highly,Variable |
R3382 |
T5178 |
T5175 |
conj |
Variable,Decreased |
R3383 |
T5179 |
T5173 |
prep |
in,Is |
R3384 |
T5180 |
T5181 |
compound |
GluR,BΔFB |
R3385 |
T5181 |
T5183 |
compound |
BΔFB,Mice |
R3386 |
T5182 |
T5181 |
punct |
-,BΔFB |
R3387 |
T5183 |
T5179 |
pobj |
Mice,in |
R3388 |
T5185 |
T5186 |
aux |
To,capture |
R3389 |
T5186 |
T5187 |
advcl |
capture,assessed |
R3390 |
T5188 |
T5189 |
det |
the,extent |
R3391 |
T5189 |
T5186 |
dobj |
extent,capture |
R3392 |
T5190 |
T5189 |
amod |
full,extent |
R3393 |
T5191 |
T5189 |
prep |
of,extent |
R3394 |
T5192 |
T5193 |
det |
the,role |
R3395 |
T5193 |
T5191 |
pobj |
role,of |
R3396 |
T5194 |
T5193 |
prep |
of,role |
R3397 |
T5195 |
T5196 |
npadvmod |
Ca2,permeable |
R3398 |
T5196 |
T5199 |
amod |
permeable,AMPARs |
R3399 |
T5197 |
T5195 |
punct |
+,Ca2 |
R3400 |
T5198 |
T5196 |
punct |
-,permeable |
R3401 |
T5199 |
T5194 |
pobj |
AMPARs,of |
R3402 |
T5200 |
T5193 |
prep |
in,role |
R3403 |
T5201 |
T5202 |
amod |
olfactory,behavior |
R3404 |
T5202 |
T5200 |
pobj |
behavior,in |
R3405 |
T5203 |
T5187 |
punct |
", ",assessed |
R3406 |
T5204 |
T5187 |
nsubj |
we,assessed |
R3407 |
T5205 |
T5187 |
advmod |
next,assessed |
R3408 |
T5206 |
T5207 |
det |
the,effects |
R3409 |
T5207 |
T5187 |
dobj |
effects,assessed |
R3410 |
T5208 |
T5207 |
prep |
of,effects |
R3411 |
T5209 |
T5210 |
amod |
altered,channels |
R3412 |
T5210 |
T5208 |
pobj |
channels,of |
R3413 |
T5211 |
T5210 |
compound |
AMPA,channels |
R3414 |
T5212 |
T5207 |
prep |
on,effects |
R3415 |
T5213 |
T5214 |
amod |
olfactory,memory |
R3416 |
T5214 |
T5212 |
pobj |
memory,on |
R3417 |
T5215 |
T5187 |
punct |
.,assessed |
R3418 |
T5217 |
T5218 |
aux |
To,probe |
R3419 |
T5218 |
T5219 |
advcl |
probe,interleaved |
R3420 |
T5220 |
T5221 |
amod |
olfactory,memory |
R3421 |
T5221 |
T5218 |
dobj |
memory,probe |
R3422 |
T5222 |
T5218 |
prep |
in,probe |
R3423 |
T5223 |
T5224 |
compound |
GluR,BΔFB |
R3424 |
T5224 |
T5226 |
compound |
BΔFB,mice |
R3425 |
T5225 |
T5224 |
punct |
-,BΔFB |
R3426 |
T5226 |
T5222 |
pobj |
mice,in |
R3427 |
T5227 |
T5219 |
punct |
", ",interleaved |
R3428 |
T5228 |
T5229 |
nummod |
six,days |
R3429 |
T5229 |
T5230 |
npadvmod |
days,after |
R3430 |
T5230 |
T5219 |
prep |
after,interleaved |
R3431 |
T5231 |
T5232 |
det |
the,end |
R3432 |
T5232 |
T5230 |
pobj |
end,after |
R3433 |
T5233 |
T5232 |
prep |
of,end |
R3434 |
T5234 |
T5235 |
det |
the,phase |
R3435 |
T5235 |
T5233 |
pobj |
phase,of |
R3436 |
T5236 |
T5235 |
amod |
first,phase |
R3437 |
T5237 |
T5235 |
compound |
training,phase |
R3438 |
T5238 |
T5235 |
prep |
for,phase |
R3439 |
T5239 |
T5240 |
compound |
odor,discrimination |
R3440 |
T5240 |
T5238 |
pobj |
discrimination,for |
R3441 |
T5241 |
T5235 |
punct |
(,phase |
R3442 |
T5242 |
T5235 |
appos |
amylacetate,phase |
R3443 |
T5243 |
T5242 |
cc |
versus,amylacetate |
R3444 |
T5244 |
T5242 |
conj |
ethylbutyrate,amylacetate |
R3445 |
T5245 |
T5235 |
punct |
),phase |
R3446 |
T5246 |
T5219 |
punct |
", ",interleaved |
R3447 |
T5247 |
T5248 |
det |
the,trials |
R3448 |
T5248 |
T5219 |
nsubjpass |
trials,interleaved |
R3449 |
T5249 |
T5248 |
compound |
training,trials |
R3450 |
T5250 |
T5248 |
prep |
for,trials |
R3451 |
T5251 |
T5252 |
det |
the,pair |
R3452 |
T5252 |
T5250 |
pobj |
pair,for |
R3453 |
T5253 |
T5252 |
amod |
third,pair |
R3454 |
T5254 |
T5252 |
compound |
odor,pair |
R3455 |
T5255 |
T5252 |
punct |
(,pair |
R3456 |
T5256 |
T5257 |
amod |
pelargonic,acid |
R3457 |
T5257 |
T5252 |
appos |
acid,pair |
R3458 |
T5258 |
T5256 |
cc |
versus,pelargonic |
R3459 |
T5259 |
T5256 |
conj |
valeric,pelargonic |
R3460 |
T5260 |
T5252 |
punct |
),pair |
R3461 |
T5261 |
T5219 |
auxpass |
were,interleaved |
R3462 |
T5262 |
T5219 |
prep |
with,interleaved |
R3463 |
T5263 |
T5264 |
amod |
unrewarded,trials |
R3464 |
T5264 |
T5262 |
pobj |
trials,with |
R3465 |
T5265 |
T5266 |
prep |
in,presented |
R3466 |
T5266 |
T5264 |
relcl |
presented,trials |
R3467 |
T5267 |
T5265 |
pobj |
which,in |
R3468 |
T5268 |
T5266 |
nsubjpass |
amylacetate,presented |
R3469 |
T5269 |
T5268 |
cc |
or,amylacetate |
R3470 |
T5270 |
T5268 |
conj |
ethylbutyrate,amylacetate |
R3471 |
T5271 |
T5266 |
auxpass |
were,presented |
R3472 |
T5272 |
T5266 |
advmod |
again,presented |
R3473 |
T5273 |
T5274 |
punct |
(,bar |
R3474 |
T5274 |
T5219 |
parataxis |
bar,interleaved |
R3475 |
T5275 |
T5274 |
amod |
black,bar |
R3476 |
T5276 |
T5274 |
prep |
in,bar |
R3477 |
T5277 |
T5278 |
compound |
Figure,2C |
R3478 |
T5278 |
T5276 |
pobj |
2C,in |
R3479 |
T5279 |
T5274 |
punct |
),bar |
R3480 |
T5280 |
T5219 |
punct |
.,interleaved |
R3481 |
T5282 |
T5283 |
mark |
Whereas,responded |
R3482 |
T5283 |
T5287 |
advcl |
responded,showed |
R3483 |
T5284 |
T5285 |
compound |
control,mice |
R3484 |
T5285 |
T5283 |
nsubj |
mice,responded |
R3485 |
T5286 |
T5283 |
advmod |
reliably,responded |
R3486 |
T5288 |
T5289 |
advmod |
only,to |
R3487 |
T5289 |
T5283 |
prep |
to,responded |
R3488 |
T5290 |
T5291 |
det |
the,odor |
R3489 |
T5291 |
T5289 |
pobj |
odor,to |
R3490 |
T5292 |
T5293 |
advmod |
previously,rewarded |
R3491 |
T5293 |
T5291 |
amod |
rewarded,odor |
R3492 |
T5294 |
T5295 |
punct |
(,2E |
R3493 |
T5295 |
T5291 |
parataxis |
2E,odor |
R3494 |
T5296 |
T5295 |
dep |
memory,2E |
R3495 |
T5297 |
T5296 |
prep |
of,memory |
R3496 |
T5298 |
T5299 |
quantmod |
86,8 |
R3497 |
T5299 |
T5301 |
nummod |
8,% |
R3498 |
T5300 |
T5299 |
punct |
±,8 |
R3499 |
T5301 |
T5297 |
pobj |
%,of |
R3500 |
T5302 |
T5295 |
punct |
", ",2E |
R3501 |
T5303 |
T5304 |
nmod |
mean,SD |
R3502 |
T5304 |
T5295 |
dep |
SD,2E |
R3503 |
T5305 |
T5304 |
punct |
±,SD |
R3504 |
T5306 |
T5295 |
punct |
", ",2E |
R3505 |
T5307 |
T5308 |
nsubj |
n,9 |
R3506 |
T5308 |
T5295 |
ccomp |
9,2E |
R3507 |
T5309 |
T5308 |
punct |
=,9 |
R3508 |
T5310 |
T5295 |
punct |
", ",2E |
R3509 |
T5311 |
T5295 |
compound |
Figure,2E |
R3510 |
T5312 |
T5295 |
punct |
),2E |
R3511 |
T5313 |
T5287 |
punct |
", ",showed |
R3512 |
T5314 |
T5315 |
compound |
GluR,BΔFB |
R3513 |
T5315 |
T5317 |
compound |
BΔFB,mice |
R3514 |
T5316 |
T5315 |
punct |
-,BΔFB |
R3515 |
T5317 |
T5287 |
nsubj |
mice,showed |
R3516 |
T5318 |
T5319 |
amod |
reduced,memory |
R3517 |
T5319 |
T5287 |
dobj |
memory,showed |
R3518 |
T5320 |
T5319 |
amod |
olfactory,memory |
R3519 |
T5321 |
T5322 |
punct |
(,Whitney |
R3520 |
T5322 |
T5287 |
parataxis |
Whitney,showed |
R3521 |
T5323 |
T5324 |
quantmod |
69,16 |
R3522 |
T5324 |
T5326 |
nummod |
16,% |
R3523 |
T5325 |
T5324 |
punct |
±,16 |
R3524 |
T5326 |
T5322 |
dep |
%,Whitney |
R3525 |
T5327 |
T5322 |
punct |
", ",Whitney |
R3526 |
T5328 |
T5329 |
nsubj |
n,9 |
R3527 |
T5329 |
T5322 |
ccomp |
9,Whitney |
R3528 |
T5330 |
T5329 |
punct |
=,9 |
R3529 |
T5331 |
T5322 |
punct |
", ",Whitney |
R3530 |
T5332 |
T5333 |
nsubj |
p,0.05 |
R3531 |
T5333 |
T5322 |
ccomp |
0.05,Whitney |
R3532 |
T5334 |
T5333 |
punct |
<,0.05 |
R3533 |
T5335 |
T5322 |
punct |
", ",Whitney |
R3534 |
T5336 |
T5322 |
compound |
Mann,Whitney |
R3535 |
T5337 |
T5322 |
punct |
-,Whitney |
R3536 |
T5338 |
T5322 |
punct |
),Whitney |
R3537 |
T5339 |
T5287 |
punct |
.,showed |
R3538 |
T5341 |
T5342 |
prep |
Due,speculate |
R3539 |
T5343 |
T5341 |
pcomp |
to,Due |
R3540 |
T5344 |
T5345 |
det |
the,learning |
R3541 |
T5345 |
T5341 |
pobj |
learning,Due |
R3542 |
T5346 |
T5347 |
advmod |
more,rapid |
R3543 |
T5347 |
T5345 |
amod |
rapid,learning |
R3544 |
T5348 |
T5345 |
acl |
observed,learning |
R3545 |
T5349 |
T5348 |
prep |
in,observed |
R3546 |
T5350 |
T5351 |
compound |
GluR,BΔFB |
R3547 |
T5351 |
T5349 |
pobj |
BΔFB,in |
R3548 |
T5352 |
T5351 |
punct |
-,BΔFB |
R3549 |
T5353 |
T5342 |
punct |
", ",speculate |
R3550 |
T5354 |
T5342 |
nsubj |
one,speculate |
R3551 |
T5355 |
T5342 |
aux |
could,speculate |
R3552 |
T5356 |
T5357 |
mark |
that,reflect |
R3553 |
T5357 |
T5342 |
ccomp |
reflect,speculate |
R3554 |
T5358 |
T5359 |
det |
a,decrease |
R3555 |
T5359 |
T5357 |
nsubj |
decrease,reflect |
R3556 |
T5360 |
T5359 |
prep |
in,decrease |
R3557 |
T5361 |
T5362 |
amod |
olfactory,memory |
R3558 |
T5362 |
T5360 |
pobj |
memory,in |
R3559 |
T5363 |
T5357 |
aux |
might,reflect |
R3560 |
T5364 |
T5357 |
advmod |
simply,reflect |
R3561 |
T5365 |
T5366 |
amod |
increased,extinction |
R3562 |
T5366 |
T5357 |
dobj |
extinction,reflect |
R3563 |
T5367 |
T5342 |
punct |
.,speculate |
R3564 |
T5369 |
T5370 |
advmod |
However,were |
R3565 |
T5371 |
T5370 |
punct |
", ",were |
R3566 |
T5372 |
T5373 |
compound |
extinction,levels |
R3567 |
T5373 |
T5370 |
nsubj |
levels,were |
R3568 |
T5374 |
T5370 |
acomp |
low,were |
R3569 |
T5375 |
T5370 |
prep |
in,were |
R3570 |
T5376 |
T5375 |
amod |
general,in |
R3571 |
T5377 |
T5370 |
punct |
", ",were |
R3572 |
T5378 |
T5379 |
det |
no,interaction |
R3573 |
T5379 |
T5384 |
nsubjpass |
interaction,found |
R3574 |
T5380 |
T5379 |
amod |
significant,interaction |
R3575 |
T5381 |
T5382 |
nmod |
group,trial |
R3576 |
T5382 |
T5379 |
compound |
trial,interaction |
R3577 |
T5383 |
T5382 |
punct |
-,trial |
R3578 |
T5384 |
T5370 |
conj |
found,were |
R3579 |
T5385 |
T5384 |
aux |
could,found |
R3580 |
T5386 |
T5384 |
auxpass |
be,found |
R3581 |
T5387 |
T5384 |
prep |
for,found |
R3582 |
T5388 |
T5389 |
det |
the,trials |
R3583 |
T5389 |
T5387 |
pobj |
trials,for |
R3584 |
T5390 |
T5389 |
compound |
memory,trials |
R3585 |
T5391 |
T5392 |
punct |
(,ANOVA |
R3586 |
T5392 |
T5384 |
parataxis |
ANOVA,found |
R3587 |
T5393 |
T5394 |
nummod |
2,way |
R3588 |
T5394 |
T5392 |
compound |
way,ANOVA |
R3589 |
T5395 |
T5394 |
punct |
-,way |
R3590 |
T5396 |
T5392 |
punct |
", ",ANOVA |
R3591 |
T5397 |
T5398 |
nsubj |
F,1.5 |
R3592 |
T5398 |
T5392 |
ccomp |
1.5,ANOVA |
R3593 |
T5399 |
T5397 |
punct |
(,F |
R3594 |
T5400 |
T5397 |
nummod |
6,F |
R3595 |
T5401 |
T5397 |
punct |
",",F |
R3596 |
T5402 |
T5397 |
nummod |
90,F |
R3597 |
T5403 |
T5397 |
punct |
),F |
R3598 |
T5404 |
T5398 |
punct |
=,1.5 |
R3599 |
T5405 |
T5392 |
punct |
", ",ANOVA |
R3600 |
T5406 |
T5407 |
nsubj |
p,0.1 |
R3601 |
T5407 |
T5392 |
ccomp |
0.1,ANOVA |
R3602 |
T5408 |
T5407 |
punct |
>,0.1 |
R3603 |
T5409 |
T5392 |
punct |
),ANOVA |
R3604 |
T5410 |
T5384 |
punct |
", ",found |
R3605 |
T5411 |
T5384 |
cc |
and,found |
R3606 |
T5412 |
T5413 |
det |
a,restriction |
R3607 |
T5413 |
T5414 |
nsubj |
restriction,displayed |
R3608 |
T5414 |
T5384 |
conj |
displayed,found |
R3609 |
T5415 |
T5413 |
prep |
of,restriction |
R3610 |
T5416 |
T5417 |
det |
the,analysis |
R3611 |
T5417 |
T5415 |
pobj |
analysis,of |
R3612 |
T5418 |
T5413 |
prep |
to,restriction |
R3613 |
T5419 |
T5420 |
amod |
early,trials |
R3614 |
T5420 |
T5418 |
pobj |
trials,to |
R3615 |
T5421 |
T5420 |
compound |
memory,trials |
R3616 |
T5422 |
T5423 |
advmod |
essentially,pattern |
R3617 |
T5423 |
T5414 |
dobj |
pattern,displayed |
R3618 |
T5424 |
T5423 |
det |
the,pattern |
R3619 |
T5425 |
T5423 |
amod |
same,pattern |
R3620 |
T5426 |
T5427 |
punct |
(,S3A |
R3621 |
T5427 |
T5414 |
parataxis |
S3A,displayed |
R3622 |
T5428 |
T5427 |
compound |
Figure,S3A |
R3623 |
T5429 |
T5427 |
punct |
),S3A |
R3624 |
T5430 |
T5370 |
punct |
.,were |
R3625 |
T5432 |
T5433 |
advmod |
Thus,is |
R3626 |
T5434 |
T5433 |
punct |
", ",is |
R3627 |
T5435 |
T5436 |
amod |
reduced,performance |
R3628 |
T5436 |
T5433 |
nsubj |
performance,is |
R3629 |
T5437 |
T5436 |
prep |
in,performance |
R3630 |
T5438 |
T5439 |
det |
the,trials |
R3631 |
T5439 |
T5437 |
pobj |
trials,in |
R3632 |
T5440 |
T5439 |
compound |
probe,trials |
R3633 |
T5441 |
T5433 |
neg |
not,is |
R3634 |
T5442 |
T5433 |
prep |
due,is |
R3635 |
T5443 |
T5442 |
pcomp |
to,due |
R3636 |
T5444 |
T5445 |
amod |
increased,extinction |
R3637 |
T5445 |
T5442 |
pobj |
extinction,due |
R3638 |
T5446 |
T5433 |
cc |
but,is |
R3639 |
T5447 |
T5433 |
conj |
reflects,is |
R3640 |
T5448 |
T5449 |
amod |
genuine,impairment |
R3641 |
T5449 |
T5447 |
dobj |
impairment,reflects |
R3642 |
T5450 |
T5449 |
compound |
memory,impairment |
R3643 |
T5451 |
T5433 |
punct |
.,is |
R3644 |
T5453 |
T5454 |
advmod |
Moreover,conclude |
R3645 |
T5455 |
T5454 |
punct |
", ",conclude |
R3646 |
T5456 |
T5457 |
mark |
because,affected |
R3647 |
T5457 |
T5454 |
advcl |
affected,conclude |
R3648 |
T5458 |
T5459 |
det |
the,acquisition |
R3649 |
T5459 |
T5457 |
nsubjpass |
acquisition,affected |
R3650 |
T5460 |
T5461 |
npadvmod |
hippocampus,dependent |
R3651 |
T5461 |
T5459 |
amod |
dependent,acquisition |
R3652 |
T5462 |
T5461 |
punct |
-,dependent |
R3653 |
T5463 |
T5459 |
amod |
spatial,acquisition |
R3654 |
T5464 |
T5459 |
nmod |
memory,acquisition |
R3655 |
T5465 |
T5466 |
nmod |
after,task |
R3656 |
T5466 |
T5459 |
compound |
task,acquisition |
R3657 |
T5467 |
T5466 |
punct |
-,task |
R3658 |
T5468 |
T5459 |
prep |
in,acquisition |
R3659 |
T5469 |
T5470 |
det |
the,maze |
R3660 |
T5470 |
T5468 |
pobj |
maze,in |
R3661 |
T5471 |
T5470 |
compound |
Y,maze |
R3662 |
T5472 |
T5470 |
punct |
-,maze |
R3663 |
T5473 |
T5457 |
auxpass |
was,affected |
R3664 |
T5474 |
T5457 |
neg |
not,affected |
R3665 |
T5475 |
T5476 |
punct |
(,S2 |
R3666 |
T5476 |
T5457 |
parataxis |
S2,affected |
R3667 |
T5477 |
T5476 |
compound |
Figure,S2 |
R3668 |
T5478 |
T5476 |
punct |
),S2 |
R3669 |
T5479 |
T5454 |
punct |
", ",conclude |
R3670 |
T5480 |
T5454 |
nsubj |
we,conclude |
R3671 |
T5481 |
T5482 |
mark |
that,is |
R3672 |
T5482 |
T5454 |
ccomp |
is,conclude |
R3673 |
T5483 |
T5484 |
det |
the,deficit |
R3674 |
T5484 |
T5482 |
nsubj |
deficit,is |
R3675 |
T5485 |
T5484 |
amod |
observed,deficit |
R3676 |
T5486 |
T5487 |
amod |
olfactory,memory |
R3677 |
T5487 |
T5484 |
compound |
memory,deficit |
R3678 |
T5488 |
T5489 |
advmod |
rather,specific |
R3679 |
T5489 |
T5482 |
acomp |
specific,is |
R3680 |
T5490 |
T5489 |
prep |
for,specific |
R3681 |
T5491 |
T5490 |
pobj |
olfaction,for |
R3682 |
T5492 |
T5482 |
cc |
and,is |
R3683 |
T5493 |
T5494 |
aux |
does,generalize |
R3684 |
T5494 |
T5482 |
conj |
generalize,is |
R3685 |
T5495 |
T5494 |
neg |
not,generalize |
R3686 |
T5496 |
T5494 |
advmod |
readily,generalize |
R3687 |
T5497 |
T5494 |
prep |
to,generalize |
R3688 |
T5498 |
T5499 |
amod |
other,modalities |
R3689 |
T5499 |
T5497 |
pobj |
modalities,to |
R3690 |
T5500 |
T5454 |
punct |
.,conclude |
R3691 |
T5502 |
T5503 |
mark |
While,showed |
R3692 |
T5503 |
T5511 |
advcl |
showed,was |
R3693 |
T5504 |
T5505 |
det |
the,behavior |
R3694 |
T5505 |
T5503 |
nsubj |
behavior,showed |
R3695 |
T5506 |
T5505 |
amod |
improved,behavior |
R3696 |
T5507 |
T5508 |
nmod |
odor,discrimination |
R3697 |
T5508 |
T5505 |
nmod |
discrimination,behavior |
R3698 |
T5509 |
T5508 |
cc |
and,discrimination |
R3699 |
T5510 |
T5508 |
conj |
learning,discrimination |
R3700 |
T5512 |
T5513 |
advmod |
only,variability |
R3701 |
T5513 |
T5503 |
dobj |
variability,showed |
R3702 |
T5514 |
T5513 |
amod |
little,variability |
R3703 |
T5515 |
T5511 |
punct |
", ",was |
R3704 |
T5516 |
T5517 |
det |
the,performance |
R3705 |
T5517 |
T5511 |
nsubj |
performance,was |
R3706 |
T5518 |
T5519 |
advmod |
significantly,impaired |
R3707 |
T5519 |
T5517 |
amod |
impaired,performance |
R3708 |
T5520 |
T5517 |
compound |
memory,performance |
R3709 |
T5521 |
T5517 |
acl |
observed,performance |
R3710 |
T5522 |
T5521 |
prep |
in,observed |
R3711 |
T5523 |
T5524 |
compound |
GluR,BΔFB |
R3712 |
T5524 |
T5526 |
compound |
BΔFB,mice |
R3713 |
T5525 |
T5524 |
punct |
-,BΔFB |
R3714 |
T5526 |
T5522 |
pobj |
mice,in |
R3715 |
T5527 |
T5528 |
advmod |
highly,variable |
R3716 |
T5528 |
T5511 |
acomp |
variable,was |
R3717 |
T5529 |
T5511 |
prep |
among,was |
R3718 |
T5530 |
T5531 |
amod |
individual,animals |
R3719 |
T5531 |
T5529 |
pobj |
animals,among |
R3720 |
T5532 |
T5511 |
prep |
compared,was |
R3721 |
T5533 |
T5532 |
prep |
with,compared |
R3722 |
T5534 |
T5535 |
compound |
control,littermates |
R3723 |
T5535 |
T5533 |
pobj |
littermates,with |
R3724 |
T5536 |
T5537 |
punct |
(,2E |
R3725 |
T5537 |
T5511 |
parataxis |
2E,was |
R3726 |
T5538 |
T5537 |
compound |
Figure,2E |
R3727 |
T5539 |
T5537 |
punct |
),2E |
R3728 |
T5540 |
T5511 |
punct |
.,was |
R3729 |
T5542 |
T5543 |
det |
This,variability |
R3730 |
T5543 |
T5544 |
nsubjpass |
variability,reflected |
R3731 |
T5545 |
T5543 |
prep |
in,variability |
R3732 |
T5546 |
T5547 |
amod |
olfactory,memory |
R3733 |
T5547 |
T5545 |
pobj |
memory,in |
R3734 |
T5548 |
T5544 |
auxpass |
was,reflected |
R3735 |
T5549 |
T5544 |
prep |
in,reflected |
R3736 |
T5550 |
T5551 |
det |
the,level |
R3737 |
T5551 |
T5549 |
pobj |
level,in |
R3738 |
T5552 |
T5551 |
cc |
and,level |
R3739 |
T5553 |
T5551 |
conj |
extent,level |
R3740 |
T5554 |
T5551 |
prep |
of,level |
R3741 |
T5555 |
T5556 |
compound |
Cre,recombinase |
R3742 |
T5556 |
T5558 |
compound |
recombinase,expression |
R3743 |
T5557 |
T5556 |
punct |
-,recombinase |
R3744 |
T5558 |
T5554 |
pobj |
expression,of |
R3745 |
T5559 |
T5544 |
prep |
in,reflected |
R3746 |
T5560 |
T5559 |
pobj |
forebrain,in |
R3747 |
T5561 |
T5560 |
prep |
of,forebrain |
R3748 |
T5562 |
T5563 |
amod |
transgenic,mice |
R3749 |
T5563 |
T5561 |
pobj |
mice,of |
R3750 |
T5564 |
T5563 |
compound |
TgCre4,mice |
R3751 |
T5565 |
T5544 |
punct |
", ",reflected |
R3752 |
T5566 |
T5567 |
mark |
as,visualized |
R3753 |
T5567 |
T5544 |
advcl |
visualized,reflected |
R3754 |
T5568 |
T5567 |
prep |
by,visualized |
R3755 |
T5569 |
T5570 |
compound |
Cre,activity |
R3756 |
T5570 |
T5568 |
pobj |
activity,by |
R3757 |
T5571 |
T5570 |
punct |
-,activity |
R3758 |
T5572 |
T5567 |
prep |
in,visualized |
R3759 |
T5573 |
T5574 |
det |
the,line |
R3760 |
T5574 |
T5572 |
pobj |
line,in |
R3761 |
T5575 |
T5576 |
compound |
Cre,indicator |
R3762 |
T5576 |
T5574 |
compound |
indicator,line |
R3763 |
T5577 |
T5576 |
punct |
-,indicator |
R3764 |
T5578 |
T5574 |
compound |
mouse,line |
R3765 |
T5579 |
T5574 |
appos |
R26R,line |
R3766 |
T5580 |
T5544 |
punct |
.,reflected |
R3767 |
T5582 |
T5583 |
nsubj |
We,observed |
R3768 |
T5584 |
T5585 |
mark |
that,varied |
R3770 |
T5586 |
T5585 |
nsubj |
onset,varied |
R3771 |
T5587 |
T5586 |
cc |
and,onset |
R3772 |
T5588 |
T5586 |
conj |
extent,onset |
R3773 |
T5589 |
T5586 |
prep |
of,onset |
R3774 |
T5590 |
T5591 |
compound |
Cre,recombinase |
R3775 |
T5591 |
T5593 |
compound |
recombinase,expression |
R3776 |
T5592 |
T5591 |
punct |
-,recombinase |
R3777 |
T5593 |
T5589 |
pobj |
expression,of |
R3778 |
T5594 |
T5593 |
prep |
in,expression |
R3779 |
T5595 |
T5596 |
amod |
different,regions |
R3780 |
T5596 |
T5594 |
pobj |
regions,in |
R3781 |
T5597 |
T5596 |
compound |
forebrain,regions |
R3782 |
T5598 |
T5585 |
prep |
among,varied |
R3783 |
T5599 |
T5600 |
amod |
individual,mice |
R3784 |
T5600 |
T5598 |
pobj |
mice,among |
R3785 |
T5601 |
T5600 |
compound |
TgCre4,mice |
R3786 |
T5602 |
T5603 |
punct |
(,3A |
R3787 |
T5603 |
T5585 |
parataxis |
3A,varied |
R3788 |
T5604 |
T5603 |
compound |
Figure,3A |
R3789 |
T5605 |
T5603 |
punct |
),3A |
R3790 |
T5606 |
T5583 |
punct |
", ",observed |
R3791 |
T5607 |
T5608 |
dep |
which,visualized |
R3792 |
T5608 |
T5583 |
advcl |
visualized,observed |
R3793 |
T5609 |
T5608 |
aux |
could,visualized |
R3794 |
T5610 |
T5608 |
advmod |
also,visualized |
R3795 |
T5611 |
T5608 |
auxpass |
be,visualized |
R3796 |
T5612 |
T5608 |
advmod |
directly,visualized |
R3797 |
T5613 |
T5608 |
prep |
by,visualized |
R3798 |
T5614 |
T5613 |
pobj |
immunohistochemistry,by |
R3799 |
T5615 |
T5608 |
prep |
with,visualized |
R3800 |
T5616 |
T5617 |
det |
a,antibody |
R3801 |
T5617 |
T5615 |
pobj |
antibody,with |
R3802 |
T5618 |
T5617 |
compound |
Cre,antibody |
R3803 |
T5619 |
T5617 |
punct |
-,antibody |
R3804 |
T5620 |
T5621 |
punct |
(,data |
R3805 |
T5621 |
T5583 |
meta |
data,observed |
R3806 |
T5622 |
T5621 |
amod |
unpublished,data |
R3807 |
T5623 |
T5621 |
punct |
),data |
R3808 |
T5624 |
T5583 |
punct |
.,observed |
R3809 |
T5626 |
T5627 |
mark |
As,persisted |
R3810 |
T5627 |
T5630 |
advcl |
persisted,attributed |
R3811 |
T5628 |
T5629 |
det |
this,variability |
R3812 |
T5629 |
T5627 |
nsubj |
variability,persisted |
R3813 |
T5631 |
T5627 |
prep |
after,persisted |
R3814 |
T5632 |
T5633 |
amod |
several,backcrosses |
R3815 |
T5633 |
T5631 |
pobj |
backcrosses,after |
R3816 |
T5634 |
T5627 |
punct |
", ",persisted |
R3817 |
T5635 |
T5627 |
cc |
and,persisted |
R3818 |
T5636 |
T5637 |
compound |
Southern,blot |
R3819 |
T5637 |
T5638 |
compound |
blot,analysis |
R3820 |
T5638 |
T5639 |
nsubj |
analysis,revealed |
R3821 |
T5639 |
T5627 |
conj |
revealed,persisted |
R3822 |
T5640 |
T5641 |
det |
no,differences |
R3823 |
T5641 |
T5639 |
dobj |
differences,revealed |
R3824 |
T5642 |
T5641 |
prep |
of,differences |
R3825 |
T5643 |
T5644 |
compound |
transgene,integration |
R3826 |
T5644 |
T5642 |
pobj |
integration,of |
R3827 |
T5645 |
T5644 |
cc |
or,integration |
R3828 |
T5646 |
T5644 |
conj |
number,integration |
R3829 |
T5647 |
T5641 |
prep |
among,differences |
R3830 |
T5648 |
T5647 |
pobj |
animals,among |
R3831 |
T5649 |
T5650 |
punct |
(,3B |
R3832 |
T5650 |
T5639 |
parataxis |
3B,revealed |
R3833 |
T5651 |
T5650 |
compound |
Figure,3B |
R3834 |
T5652 |
T5650 |
punct |
),3B |
R3835 |
T5653 |
T5630 |
punct |
", ",attributed |
R3836 |
T5654 |
T5630 |
nsubjpass |
it,attributed |
R3837 |
T5655 |
T5630 |
aux |
could,attributed |
R3838 |
T5656 |
T5630 |
neg |
not,attributed |
R3839 |
T5657 |
T5630 |
auxpass |
be,attributed |
R3840 |
T5658 |
T5630 |
prep |
to,attributed |
R3841 |
T5659 |
T5660 |
amod |
genetic,differences |
R3842 |
T5660 |
T5658 |
pobj |
differences,to |
R3843 |
T5661 |
T5658 |
cc |
but,to |
R3844 |
T5662 |
T5661 |
advmod |
rather,but |
R3845 |
T5663 |
T5658 |
conj |
to,to |
R3846 |
T5664 |
T5665 |
amod |
epigenetic,mechanisms |
R3847 |
T5665 |
T5663 |
pobj |
mechanisms,to |
R3848 |
T5666 |
T5630 |
punct |
.,attributed |
R3849 |
T5668 |
T5669 |
advmod |
Hence,hypothesized |
R3850 |
T5670 |
T5669 |
punct |
", ",hypothesized |
R3851 |
T5671 |
T5669 |
nsubj |
we,hypothesized |
R3852 |
T5672 |
T5673 |
mark |
that,reflected |
R3853 |
T5673 |
T5669 |
ccomp |
reflected,hypothesized |
R3854 |
T5674 |
T5675 |
det |
the,variability |
R3855 |
T5675 |
T5673 |
nsubj |
variability,reflected |
R3856 |
T5676 |
T5675 |
prep |
in,variability |
R3857 |
T5677 |
T5678 |
amod |
olfactory,memory |
R3858 |
T5678 |
T5676 |
pobj |
memory,in |
R3859 |
T5679 |
T5680 |
det |
the,mosaicism |
R3860 |
T5680 |
T5673 |
dobj |
mosaicism,reflected |
R3861 |
T5681 |
T5680 |
acl |
observed,mosaicism |
R3862 |
T5682 |
T5681 |
prep |
in,observed |
R3863 |
T5683 |
T5684 |
det |
the,line |
R3864 |
T5684 |
T5682 |
pobj |
line,in |
R3865 |
T5685 |
T5684 |
amod |
transgenic,line |
R3866 |
T5686 |
T5684 |
compound |
TgCre4,line |
R3867 |
T5687 |
T5669 |
punct |
.,hypothesized |
R3868 |
T5689 |
T5690 |
det |
The,evaluation |
R3869 |
T5690 |
T5691 |
nsubjpass |
evaluation,applied |
R3870 |
T5692 |
T5690 |
prep |
of,evaluation |
R3871 |
T5693 |
T5694 |
amod |
regional,differences |
R3872 |
T5694 |
T5692 |
pobj |
differences,of |
R3873 |
T5695 |
T5694 |
prep |
in,differences |
R3874 |
T5696 |
T5697 |
compound |
expression,pattern |
R3875 |
T5697 |
T5695 |
pobj |
pattern,in |
R3876 |
T5698 |
T5697 |
prep |
of,pattern |
R3877 |
T5699 |
T5698 |
pobj |
animals,of |
R3878 |
T5700 |
T5699 |
prep |
with,animals |
R3879 |
T5701 |
T5702 |
amod |
robust,memory |
R3880 |
T5702 |
T5700 |
pobj |
memory,with |
R3881 |
T5703 |
T5701 |
cc |
and,robust |
R3882 |
T5704 |
T5701 |
conj |
poor,robust |
R3883 |
T5705 |
T5702 |
amod |
olfactory,memory |
R3884 |
T5706 |
T5691 |
aux |
could,applied |
R3885 |
T5707 |
T5691 |
advmod |
then,applied |
R3886 |
T5708 |
T5691 |
auxpass |
be,applied |
R3887 |
T5709 |
T5710 |
aux |
to,identify |
R3888 |
T5710 |
T5691 |
advcl |
identify,applied |
R3889 |
T5711 |
T5712 |
compound |
brain,areas |
R3890 |
T5712 |
T5710 |
dobj |
areas,identify |
R3891 |
T5713 |
T5712 |
amod |
responsible,areas |
R3892 |
T5714 |
T5713 |
prep |
for,responsible |
R3893 |
T5715 |
T5716 |
det |
the,phenotypes |
R3894 |
T5716 |
T5714 |
pobj |
phenotypes,for |
R3895 |
T5717 |
T5716 |
amod |
observed,phenotypes |
R3896 |
T5718 |
T5691 |
punct |
.,applied |
R3769 |
T5585 |
T5583 |
ccomp |
varied,observed |