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PMC:1253828 / 6875-7704 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T2279 474-478 IN denotes from
T2293 541-543 NN denotes pC
T2173 0-6 NN denotes Animal
T2174 7-16 NN denotes treatment
T2175 16-414 sentence denotes At 8 weeks of age, male Mtf1loxP/loxP mice harboring the Mx-cre transgene (Mtf1loxP/loxP Mx-cre, abbr.: Mtf1Mx-cre) and control littermates without transgene (Mtf1loxP/loxP, abbr.: Mtf1loxP) received four intraperitoneal injections each of 300 µg synthetic double-stranded RNA polyinosinic–polycytidylic acid [pI–pC; Sigma; in a volume of 60 µl phosphate-buffered saline (PBS)] at 3 day intervals.
T2176 17-19 IN denotes At
T2177 208-216 VBD denotes received
T2178 20-21 CD denotes 8
T2179 22-27 NNS denotes weeks
T2180 28-30 IN denotes of
T2181 31-34 NN denotes age
T2182 34-36 , denotes ,
T2183 36-40 JJ denotes male
T2184 55-59 NNS denotes mice
T2185 41-49 NN denotes Mtf1loxP
T2186 50-54 NN denotes loxP
T2187 49-50 HYPH denotes /
T2188 60-69 VBG denotes harboring
T2189 70-73 DT denotes the
T2190 81-90 NN denotes transgene
T2191 74-76 NN denotes Mx
T2192 77-80 NN denotes cre
T2193 76-77 HYPH denotes -
T2194 91-92 -LRB- denotes (
T2195 92-100 NN denotes Mtf1loxP
T2196 109-112 NN denotes cre
T2197 100-101 HYPH denotes /
T2198 101-105 NN denotes loxP
T2199 106-108 NN denotes Mx
T2200 108-109 HYPH denotes -
T2201 112-114 , denotes ,
T2202 114-119 RB denotes abbr.
T2203 128-131 NN denotes cre
T2204 119-121 : denotes :
T2205 121-127 NN denotes Mtf1Mx
T2206 127-128 HYPH denotes -
T2207 131-132 -RRB- denotes )
T2208 133-136 CC denotes and
T2209 137-144 NN denotes control
T2210 145-156 NNS denotes littermates
T2211 157-164 IN denotes without
T2212 165-174 NN denotes transgene
T2213 175-176 -LRB- denotes (
T2214 176-184 NN denotes Mtf1loxP
T2215 185-189 NN denotes loxP
T2216 184-185 HYPH denotes /
T2217 189-191 , denotes ,
T2218 191-196 NN denotes abbr.
T2219 198-206 NN denotes Mtf1loxP
T2220 196-198 : denotes :
T2221 206-207 -RRB- denotes )
T2222 217-221 CD denotes four
T2223 238-248 NNS denotes injections
T2224 222-237 JJ denotes intraperitoneal
T2225 249-253 RB denotes each
T2226 254-256 IN denotes of
T2227 257-260 CD denotes 300
T2228 261-263 NN denotes µg
T2229 321-325 NN denotes acid
T2230 264-273 JJ denotes synthetic
T2231 274-280 JJ denotes double
T2232 281-289 VBN denotes stranded
T2233 688-690 CD denotes 20
T2234 280-281 HYPH denotes -
T2235 290-293 NN denotes RNA
T2236 294-306 JJ denotes polyinosinic
T2237 307-320 JJ denotes polycytidylic
T2238 306-307 HYPH denotes
T2239 326-327 -LRB- denotes [
T2240 334-339 NNP denotes Sigma
T2241 327-329 NN denotes pI
T2242 330-332 NN denotes pC
T2243 329-330 HYPH denotes
T2244 332-333 : denotes ;
T2245 339-340 : denotes ;
T2246 341-343 IN denotes in
T2247 344-345 DT denotes a
T2248 346-352 NN denotes volume
T2249 353-355 IN denotes of
T2250 356-358 CD denotes 60
T2251 359-361 NN denotes µl
T2252 362-371 NN denotes phosphate
T2253 372-380 VBN denotes buffered
T2254 371-372 HYPH denotes -
T2255 381-387 NN denotes saline
T2256 388-389 -LRB- denotes (
T2257 389-392 NN denotes PBS
T2258 392-393 -RRB- denotes )
T2259 393-394 -RRB- denotes ]
T2260 395-397 IN denotes at
T2261 398-399 CD denotes 3
T2262 400-403 NN denotes day
T2263 404-413 NNS denotes intervals
T2264 413-414 . denotes .
T2265 414-555 sentence denotes Only in the case of DNA-binding studies with MRE sequences from MTF-1 target gene candidates, the control mice received no pI–pC injections.
T2266 415-419 RB denotes Only
T2267 420-422 IN denotes in
T2268 526-534 VBD denotes received
T2269 423-426 DT denotes the
T2270 427-431 NN denotes case
T2271 432-434 IN denotes of
T2272 435-438 NN denotes DNA
T2273 439-446 VBG denotes binding
T2274 438-439 HYPH denotes -
T2275 447-454 NNS denotes studies
T2276 455-459 IN denotes with
T2277 460-463 NN denotes MRE
T2278 464-473 NNS denotes sequences
T2280 479-482 NN denotes MTF
T2281 497-507 NNS denotes candidates
T2282 482-483 HYPH denotes -
T2283 483-484 CD denotes 1
T2284 485-491 NN denotes target
T2285 492-496 NN denotes gene
T2286 507-509 , denotes ,
T2287 509-512 DT denotes the
T2288 521-525 NNS denotes mice
T2289 513-520 NN denotes control
T2290 535-537 DT denotes no
T2291 544-554 NNS denotes injections
T2292 538-540 NN denotes pI
T2294 540-541 HYPH denotes
T2295 554-555 . denotes .
T2296 555-829 sentence denotes For experiments with metal treatment, mice received 2 days after the last pI–pC treatment a subcutaneous (s.c.) injection of either 20 µmol/kg body weight CdSO4 (2 mM CdSO4 in H2O; cadmium treatment) or 10 ml/kg body weight H2O (mock treatment) 6 h before sacrificing them.
T2297 556-559 IN denotes For
T2298 599-607 VBD denotes received
T2299 560-571 NNS denotes experiments
T2300 572-576 IN denotes with
T2301 577-582 NN denotes metal
T2302 583-592 NN denotes treatment
T2303 592-594 , denotes ,
T2304 594-598 NNS denotes mice
T2305 608-609 CD denotes 2
T2306 610-614 NNS denotes days
T2307 615-620 IN denotes after
T2308 621-624 DT denotes the
T2309 636-645 NN denotes treatment
T2310 625-629 JJ denotes last
T2311 630-632 NN denotes pI
T2312 633-635 NN denotes pC
T2313 632-633 HYPH denotes
T2314 646-647 DT denotes a
T2315 668-677 NN denotes injection
T2316 648-660 JJ denotes subcutaneous
T2317 662-666 JJ denotes s.c.
T2318 661-662 -LRB- denotes (
T2319 666-667 -RRB- denotes )
T2320 678-680 IN denotes of
T2321 681-687 CC denotes either
T2322 711-716 NN denotes CdSO4
T2323 691-695 NN denotes µmol
T2324 695-696 SYM denotes /
T2325 704-710 NN denotes weight
T2326 696-698 NN denotes kg
T2327 699-703 NN denotes body
T2328 717-718 -LRB- denotes (
T2329 745-754 NN denotes treatment
T2330 718-719 CD denotes 2
T2331 720-722 NN denotes mM
T2334 732-735 NN denotes H2O
T2332 723-728 NN denotes CdSO4
T2333 729-731 IN denotes in
T2335 735-736 : denotes ;
T2336 737-744 NN denotes cadmium
T2337 754-755 -RRB- denotes )
T2338 756-758 CC denotes or
T2339 759-761 CD denotes 10
T2340 762-764 NN denotes ml
T2341 780-783 NN denotes H2O
T2342 764-765 SYM denotes /
T2343 773-779 NN denotes weight
T2344 765-767 NN denotes kg
T2345 768-772 NN denotes body
T2346 784-785 -LRB- denotes (
T2347 790-799 NN denotes treatment
T2348 785-789 JJ denotes mock
T2349 799-800 -RRB- denotes )
T2350 801-802 CD denotes 6
T2351 803-804 NN denotes h
T2352 805-811 IN denotes before
T2353 812-823 VBG denotes sacrificing
T2354 824-828 PRP denotes them
T2355 828-829 . denotes .
R1309 T2173 T2174 compound Animal,treatment
R1310 T2176 T2177 prep At,received
R1311 T2178 T2179 nummod 8,weeks
R1312 T2179 T2176 pobj weeks,At
R1313 T2180 T2179 prep of,weeks
R1314 T2181 T2180 pobj age,of
R1315 T2182 T2177 punct ", ",received
R1316 T2183 T2184 amod male,mice
R1317 T2184 T2177 nsubj mice,received
R1318 T2185 T2186 compound Mtf1loxP,loxP
R1319 T2186 T2184 compound loxP,mice
R1320 T2187 T2186 punct /,loxP
R1321 T2188 T2184 acl harboring,mice
R1322 T2189 T2190 det the,transgene
R1323 T2190 T2188 dobj transgene,harboring
R1324 T2191 T2192 compound Mx,cre
R1325 T2192 T2190 compound cre,transgene
R1326 T2193 T2192 punct -,cre
R1327 T2194 T2190 punct (,transgene
R1328 T2195 T2196 compound Mtf1loxP,cre
R1330 T2197 T2196 punct /,cre
R1331 T2198 T2196 compound loxP,cre
R1332 T2199 T2196 compound Mx,cre
R1333 T2200 T2196 punct -,cre
R1334 T2201 T2196 punct ", ",cre
R1335 T2202 T2203 advmod abbr.,cre
R1336 T2203 T2196 appos cre,cre
R1337 T2204 T2203 punct : ,cre
R1338 T2205 T2203 compound Mtf1Mx,cre
R1339 T2206 T2203 punct -,cre
R1340 T2207 T2190 punct ),transgene
R1341 T2208 T2190 cc and,transgene
R1342 T2209 T2210 compound control,littermates
R1343 T2210 T2190 conj littermates,transgene
R1344 T2211 T2210 prep without,littermates
R1345 T2212 T2211 pobj transgene,without
R1346 T2213 T2210 punct (,littermates
R1347 T2214 T2215 compound Mtf1loxP,loxP
R1348 T2215 T2210 appos loxP,littermates
R1349 T2216 T2215 punct /,loxP
R1350 T2217 T2215 punct ", ",loxP
R1351 T2218 T2219 advmod abbr.,Mtf1loxP
R1352 T2219 T2215 appos Mtf1loxP,loxP
R1353 T2220 T2219 punct : ,Mtf1loxP
R1354 T2221 T2177 punct ),received
R1355 T2222 T2223 nummod four,injections
R1356 T2223 T2177 dobj injections,received
R1357 T2224 T2223 amod intraperitoneal,injections
R1358 T2225 T2223 advmod each,injections
R1359 T2226 T2223 prep of,injections
R1360 T2227 T2228 nummod 300,µg
R1361 T2228 T2229 nmod µg,acid
R1362 T2229 T2226 pobj acid,of
R1363 T2230 T2229 amod synthetic,acid
R1364 T2231 T2232 amod double,stranded
R1365 T2232 T2229 amod stranded,acid
R1366 T2233 T2323 nummod 20,µmol
R1367 T2234 T2232 punct -,stranded
R1368 T2235 T2229 nmod RNA,acid
R1369 T2236 T2237 amod polyinosinic,polycytidylic
R1370 T2237 T2229 amod polycytidylic,acid
R1371 T2238 T2237 punct –,polycytidylic
R1372 T2239 T2240 punct [,Sigma
R1373 T2240 T2229 parataxis Sigma,acid
R1374 T2241 T2242 compound pI,pC
R1375 T2242 T2240 dep pC,Sigma
R1376 T2243 T2242 punct –,pC
R1377 T2244 T2240 punct ;,Sigma
R1378 T2245 T2240 punct ;,Sigma
R1379 T2246 T2240 prep in,Sigma
R1380 T2247 T2248 det a,volume
R1381 T2248 T2246 pobj volume,in
R1382 T2249 T2248 prep of,volume
R1383 T2250 T2251 nummod 60,µl
R1384 T2251 T2249 pobj µl,of
R1385 T2252 T2253 npadvmod phosphate,buffered
R1386 T2253 T2255 amod buffered,saline
R1387 T2254 T2253 punct -,buffered
R1388 T2255 T2251 appos saline,µl
R1389 T2256 T2255 punct (,saline
R1390 T2257 T2255 appos PBS,saline
R1391 T2258 T2240 punct ),Sigma
R1392 T2259 T2240 punct ],Sigma
R1393 T2260 T2177 prep at,received
R1394 T2261 T2262 nummod 3,day
R1395 T2262 T2263 compound day,intervals
R1396 T2263 T2260 pobj intervals,at
R1397 T2264 T2177 punct .,received
R1398 T2266 T2267 advmod Only,in
R1399 T2267 T2268 prep in,received
R1400 T2269 T2270 det the,case
R1401 T2270 T2267 pobj case,in
R1402 T2271 T2270 prep of,case
R1403 T2272 T2273 npadvmod DNA,binding
R1404 T2273 T2275 amod binding,studies
R1405 T2274 T2273 punct -,binding
R1406 T2275 T2271 pobj studies,of
R1407 T2276 T2275 prep with,studies
R1408 T2277 T2278 compound MRE,sequences
R1409 T2278 T2276 pobj sequences,with
R1410 T2279 T2278 prep from,sequences
R1411 T2280 T2281 nmod MTF,candidates
R1412 T2281 T2279 pobj candidates,from
R1413 T2282 T2280 punct -,MTF
R1414 T2283 T2280 nummod 1,MTF
R1415 T2284 T2285 compound target,gene
R1416 T2285 T2281 compound gene,candidates
R1417 T2286 T2268 punct ", ",received
R1418 T2287 T2288 det the,mice
R1419 T2288 T2268 nsubj mice,received
R1420 T2289 T2288 compound control,mice
R1421 T2290 T2291 det no,injections
R1422 T2291 T2268 dobj injections,received
R1423 T2292 T2293 compound pI,pC
R1424 T2293 T2291 compound pC,injections
R1425 T2294 T2293 punct –,pC
R1426 T2295 T2268 punct .,received
R1427 T2297 T2298 prep For,received
R1428 T2299 T2297 pobj experiments,For
R1429 T2300 T2299 prep with,experiments
R1430 T2301 T2302 compound metal,treatment
R1431 T2302 T2300 pobj treatment,with
R1432 T2303 T2298 punct ", ",received
R1433 T2304 T2298 nsubj mice,received
R1434 T2305 T2306 nummod 2,days
R1435 T2306 T2307 npadvmod days,after
R1436 T2307 T2298 prep after,received
R1437 T2308 T2309 det the,treatment
R1438 T2309 T2307 pobj treatment,after
R1439 T2310 T2309 amod last,treatment
R1440 T2311 T2312 compound pI,pC
R1441 T2312 T2309 compound pC,treatment
R1442 T2313 T2312 punct –,pC
R1443 T2314 T2315 det a,injection
R1444 T2315 T2298 dobj injection,received
R1445 T2316 T2317 amod subcutaneous,s.c.
R1446 T2317 T2315 amod s.c.,injection
R1447 T2318 T2317 punct (,s.c.
R1448 T2319 T2315 punct ),injection
R1449 T2320 T2315 prep of,injection
R1450 T2321 T2322 preconj either,CdSO4
R1451 T2322 T2320 pobj CdSO4,of
R1452 T2323 T2322 nmod µmol,CdSO4
R1453 T2324 T2325 punct /,weight
R1454 T2325 T2323 prep weight,µmol
R1455 T2326 T2325 compound kg,weight
R1456 T2327 T2325 compound body,weight
R1457 T2328 T2329 punct (,treatment
R1458 T2329 T2322 parataxis treatment,CdSO4
R1459 T2330 T2331 nummod 2,mM
R1460 T2331 T2332 compound mM,CdSO4
R1461 T2332 T2329 dep CdSO4,treatment
R1462 T2333 T2332 prep in,CdSO4
R1463 T2334 T2333 pobj H2O,in
R1464 T2335 T2329 punct ;,treatment
R1465 T2336 T2329 compound cadmium,treatment
R1466 T2337 T2329 punct ),treatment
R1467 T2338 T2322 cc or,CdSO4
R1468 T2339 T2340 nummod 10,ml
R1469 T2340 T2341 nmod ml,H2O
R1471 T2342 T2343 punct /,weight
R1472 T2343 T2340 prep weight,ml
R1473 T2344 T2343 compound kg,weight
R1474 T2345 T2343 compound body,weight
R1475 T2346 T2347 punct (,treatment
R1476 T2347 T2341 parataxis treatment,H2O
R1477 T2348 T2347 amod mock,treatment
R1478 T2349 T2347 punct ),treatment
R1479 T2350 T2351 nummod 6,h
R1480 T2351 T2352 npadvmod h,before
R1481 T2352 T2298 prep before,received
R1482 T2353 T2352 pcomp sacrificing,before
R1483 T2354 T2353 dobj them,sacrificing
R1484 T2355 T2298 punct .,received
R1329 T2196 T2190 appos cre,transgene
R1470 T2341 T2322 conj H2O,CdSO4

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T2371 180-184 SO:0000346 denotes loxP
T2372 185-189 SO:0000346 denotes loxP
T2373 198-202 PR:000010717 denotes Mtf1
T2374 202-206 SO:0000346 denotes loxP
T2375 227-237 UBERON:0001179 denotes peritoneal
T2376 274-289 SO:0000985 denotes double-stranded
T2377 294-306 _FRAGMENT denotes polyinosinic
T2378 321-325 CHEBI:76777 denotes acid
T2379 327-329 CHEBI:76777 denotes pI
T2380 479-484 PR:000010717 denotes MTF-1
T2381 492-496 SO:0000704 denotes gene
T2382 521-525 NCBITaxon:10088 denotes mice
T2383 538-540 CHEBI:76777 denotes pI
T2384 594-598 NCBITaxon:10088 denotes mice
T2385 630-632 CHEBI:76777 denotes pI
T2386 711-716 CHEBI:50292 denotes CdSO4
T2387 723-728 CHEBI:50292 denotes CdSO4
T2388 732-735 CHEBI:15377 denotes H2O
T2389 780-783 CHEBI:15377 denotes H2O
T2356 0-6 NCBITaxon:33208 denotes Animal
T2357 41-45 PR:000010717 denotes Mtf1
T2358 45-49 SO:0000346 denotes loxP
T2359 50-54 SO:0000346 denotes loxP
T2360 55-59 NCBITaxon:10088 denotes mice
T2361 74-76 PR:000010788 denotes Mx
T2362 81-90 SO:0000902 denotes transgene
T2363 92-96 PR:000010717 denotes Mtf1
T2364 96-100 SO:0000346 denotes loxP
T2365 101-105 SO:0000346 denotes loxP
T2366 106-108 PR:000010788 denotes Mx
T2367 121-125 PR:000010717 denotes Mtf1
T2368 125-127 PR:000010788 denotes Mx
T2369 165-174 SO:0000902 denotes transgene
T2370 176-180 PR:000010717 denotes Mtf1
R1485 T2378 T2377 _lexicallyChainedTo acid,polyinosinic

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T2405 176-180 PR_EXT:000010717 denotes Mtf1
T2406 180-184 SO_EXT:0000346 denotes loxP
T2407 185-189 SO_EXT:0000346 denotes loxP
T2408 198-202 PR_EXT:000010717 denotes Mtf1
T2409 202-206 SO_EXT:0000346 denotes loxP
T2410 227-237 UBERON:0001179 denotes peritoneal
T2411 274-293 CHEBI_SO_EXT:double_stranded_RNA denotes double-stranded RNA
T2412 294-306 _FRAGMENT denotes polyinosinic
T2413 321-325 CHEBI:76777 denotes acid
T2414 298-306 CHEBI_SO_EXT:inosine denotes inosinic
T2415 307-325 CHEBI_EXT:polyC_acid denotes polycytidylic acid
T2416 327-329 CHEBI:76777 denotes pI
T2417 330-332 CHEBI_EXT:polyC_acid denotes pC
T2418 362-371 CHEBI_EXT:phosphate denotes phosphate
T2419 372-380 CHEBI_CHMO_EXT:buffer_process denotes buffered
T2420 381-387 CHEBI_EXT:saline_solution denotes saline
T2421 435-438 CHEBI_SO_EXT:DNA denotes DNA
T2422 439-446 CHEMINF_GO_EXT:chemical_binding_or_bond_formation denotes binding
T2423 464-473 SO_EXT:biological_sequence denotes sequences
T2424 479-484 PR_EXT:000010717 denotes MTF-1
T2425 492-496 SO_EXT:0000704 denotes gene
T2426 521-525 NCBITaxon:10088 denotes mice
T2427 538-540 CHEBI:76777 denotes pI
T2428 541-543 CHEBI_EXT:polyC_acid denotes pC
T2429 577-582 CHEBI_EXT:metal denotes metal
T2430 594-598 NCBITaxon:10088 denotes mice
T2431 630-632 CHEBI:76777 denotes pI
T2432 633-635 CHEBI_EXT:polyC_acid denotes pC
T2433 651-660 UBERON_EXT:zone_of_skin_or_skin_of_body denotes cutaneous
T2434 664-666 UBERON_EXT:zone_of_skin_or_skin_of_body denotes c.
T2435 699-703 UBERON_EXT:body denotes body
T2436 711-716 CHEBI:50292 denotes CdSO4
T2437 723-728 CHEBI:50292 denotes CdSO4
T2438 732-735 CHEBI:15377 denotes H2O
T2439 737-744 CHEBI_EXT:cadmium denotes cadmium
T2440 768-772 UBERON_EXT:body denotes body
T2441 780-783 CHEBI:15377 denotes H2O
T2442 812-823 GO_EXT:killing denotes sacrificing
T2390 0-6 NCBITaxon:33208 denotes Animal
T2391 36-40 PATO_UBERON_EXT:male_or_bearer_of_maleness denotes male
T2392 41-45 PR_EXT:000010717 denotes Mtf1
T2393 45-49 SO_EXT:0000346 denotes loxP
T2394 50-54 SO_EXT:0000346 denotes loxP
T2395 55-59 NCBITaxon:10088 denotes mice
T2396 74-76 PR_EXT:000010788 denotes Mx
T2397 81-90 SO_EXT:0000902 denotes transgene
T2398 92-96 PR_EXT:000010717 denotes Mtf1
T2399 96-100 SO_EXT:0000346 denotes loxP
T2400 101-105 SO_EXT:0000346 denotes loxP
T2401 106-108 PR_EXT:000010788 denotes Mx
T2402 121-125 PR_EXT:000010717 denotes Mtf1
T2403 125-127 PR_EXT:000010788 denotes Mx
T2404 165-174 SO_EXT:0000902 denotes transgene
R1486 T2413 T2412 _lexicallyChainedTo acid,polyinosinic