PMC:1253828 / 37466-37758
Annnotations
craft-sa-dev
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The enhanced sensitivity to cadmium toxicity that we found for mouse embryonic fibroblasts upon a combination of Mtf1 deletion and depletion of glutathione further corroborates the importance of MTF-1 and its target genes as well as reduced glutathione for an efficient anti-cadmium defense."}
craft-ca-core-dev
{"project":"craft-ca-core-dev","denotations":[{"id":"T9318","span":{"begin":64,"end":69},"obj":"NCBITaxon:10088"},{"id":"T9319","span":{"begin":70,"end":79},"obj":"UBERON:0000922"},{"id":"T9320","span":{"begin":80,"end":91},"obj":"CL:0000057"},{"id":"T9321","span":{"begin":114,"end":118},"obj":"PR:000010717"},{"id":"T9322","span":{"begin":145,"end":156},"obj":"CHEBI:16856"},{"id":"T9323","span":{"begin":196,"end":201},"obj":"PR:000010717"},{"id":"T9324","span":{"begin":217,"end":222},"obj":"SO:0000704"},{"id":"T9325","span":{"begin":234,"end":241},"obj":"MOP:0000569"},{"id":"T9326","span":{"begin":234,"end":253},"obj":"CHEBI:16856"},{"id":"T9327","span":{"begin":284,"end":291},"obj":"GO:0006952"}],"text":" The enhanced sensitivity to cadmium toxicity that we found for mouse embryonic fibroblasts upon a combination of Mtf1 deletion and depletion of glutathione further corroborates the importance of MTF-1 and its target genes as well as reduced glutathione for an efficient anti-cadmium defense."}
craft-ca-core-ex-dev
{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T9765","span":{"begin":29,"end":36},"obj":"CHEBI_EXT:cadmium"},{"id":"T9766","span":{"begin":64,"end":69},"obj":"NCBITaxon:10088"},{"id":"T9767","span":{"begin":70,"end":79},"obj":"UBERON:0000922"},{"id":"T9768","span":{"begin":80,"end":91},"obj":"CL:0000057"},{"id":"T9769","span":{"begin":114,"end":118},"obj":"PR_EXT:000010717"},{"id":"T9770","span":{"begin":119,"end":127},"obj":"SO_EXT:sequence_deletion_entity_or_process"},{"id":"T9771","span":{"begin":145,"end":156},"obj":"CHEBI:16856"},{"id":"T9772","span":{"begin":196,"end":201},"obj":"PR_EXT:000010717"},{"id":"T9773","span":{"begin":217,"end":222},"obj":"SO_EXT:0000704"},{"id":"T9774","span":{"begin":234,"end":241},"obj":"MOP:0000569"},{"id":"T9775","span":{"begin":234,"end":253},"obj":"CHEBI:16856"},{"id":"T9776","span":{"begin":276,"end":283},"obj":"CHEBI_EXT:cadmium"},{"id":"T9777","span":{"begin":284,"end":291},"obj":"GO:0006952"}],"text":" The enhanced sensitivity to cadmium toxicity that we found for mouse embryonic fibroblasts upon a combination of Mtf1 deletion and depletion of glutathione further corroborates the importance of MTF-1 and its target genes as well as reduced glutathione for an efficient anti-cadmium defense."}