PMC:1253828 / 3663-3905 JSONTXT

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In contrast, mice with null mutations for the stress-inducible metallothionein genes (Mt1 and Mt2) are viable, though sensitive to cadmium (24,25), indicating that additional important MTF-1 target genes are involved in the lethal phenotype."}

{"project":"2_test","denotations":[{"id":"16221973-8367468-77403410","span":{"begin":141,"end":143},"obj":"8367468"},{"id":"16221973-8290567-77403411","span":{"begin":144,"end":146},"obj":"8290567"}],"text":" In contrast, mice with null mutations for the stress-inducible metallothionein genes (Mt1 and Mt2) are viable, though sensitive to cadmium (24,25), indicating that additional important MTF-1 target genes are involved in the lethal phenotype."}

{"project":"craft-ca-core-dev","denotations":[{"id":"T760","span":{"begin":14,"end":18},"obj":"NCBITaxon:10088"},{"id":"T761","span":{"begin":80,"end":85},"obj":"SO:0000704"},{"id":"T762","span":{"begin":87,"end":90},"obj":"PR:000010925"},{"id":"T763","span":{"begin":95,"end":98},"obj":"PR:000010704"},{"id":"T764","span":{"begin":186,"end":191},"obj":"PR:000010717"},{"id":"T765","span":{"begin":199,"end":204},"obj":"SO:0000704"}],"text":" In contrast, mice with null mutations for the stress-inducible metallothionein genes (Mt1 and Mt2) are viable, though sensitive to cadmium (24,25), indicating that additional important MTF-1 target genes are involved in the lethal phenotype."}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T901","span":{"begin":14,"end":18},"obj":"NCBITaxon:10088"},{"id":"T902","span":{"begin":24,"end":28},"obj":"SO_EXT:sequence_nullness"},{"id":"T903","span":{"begin":29,"end":38},"obj":"SO_EXT:sequence_alteration_entity_or_process"},{"id":"T904","span":{"begin":80,"end":85},"obj":"SO_EXT:0000704"},{"id":"T905","span":{"begin":87,"end":90},"obj":"PR_EXT:000010925"},{"id":"T906","span":{"begin":95,"end":98},"obj":"PR_EXT:000010704"},{"id":"T907","span":{"begin":132,"end":139},"obj":"CHEBI_EXT:cadmium"},{"id":"T908","span":{"begin":186,"end":191},"obj":"PR_EXT:000010717"},{"id":"T909","span":{"begin":199,"end":204},"obj":"SO_EXT:0000704"},{"id":"T910","span":{"begin":225,"end":231},"obj":"GO_EXT:fatality_or_lethality"}],"text":" In contrast, mice with null mutations for the stress-inducible metallothionein genes (Mt1 and Mt2) are viable, though sensitive to cadmium (24,25), indicating that additional important MTF-1 target genes are involved in the lethal phenotype."}