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PMC:1253828 / 26480-26988 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T8228 0-508 sentence denotes Several genes involved in the metabolism of the antioxidant glutathione were found to be upregulated by cadmium exposure, namely the genes encoding the catalytic subunit of glutamate-cysteine ligase (Gclc) that is the rate limiting enzyme in de novo synthesis of glutathione (45); glutathione reductase 1 (Gsr), the reducing enzyme for oxidized glutathione (45); and glutathione-S-transferase, mu 4 (Gstm4), which is a member of the glutathione-S-transferase supergene family of detoxification enzymes (45).
T8229 1-8 JJ denotes Several
T8230 9-14 NNS denotes genes
T8231 78-83 VBN denotes found
T8232 15-23 VBN denotes involved
T8233 24-26 IN denotes in
T8234 27-30 DT denotes the
T8235 31-41 NN denotes metabolism
T8236 42-44 IN denotes of
T8237 45-48 DT denotes the
T8238 61-72 NN denotes glutathione
T8239 49-60 NN denotes antioxidant
T8240 73-77 VBD denotes were
T8241 84-86 TO denotes to
T8242 90-101 VBN denotes upregulated
T8243 87-89 VB denotes be
T8244 102-104 IN denotes by
T8245 105-112 NN denotes cadmium
T8246 113-121 NN denotes exposure
T8247 121-123 , denotes ,
T8248 123-129 RB denotes namely
T8249 134-139 NNS denotes genes
T8250 130-133 DT denotes the
T8251 140-148 VBG denotes encoding
T8252 149-152 DT denotes the
T8253 163-170 NN denotes subunit
T8254 153-162 JJ denotes catalytic
T8255 171-173 IN denotes of
T8256 174-183 NN denotes glutamate
T8257 193-199 NN denotes ligase
T8258 183-184 HYPH denotes -
T8259 184-192 NN denotes cysteine
T8260 200-201 -LRB- denotes (
T8261 201-205 NN denotes Gclc
T8262 205-206 -RRB- denotes )
T8263 207-211 WDT denotes that
T8264 212-214 VBZ denotes is
T8265 215-218 DT denotes the
T8266 233-239 NN denotes enzyme
T8267 219-223 NN denotes rate
T8268 224-232 VBG denotes limiting
T8269 240-242 IN denotes in
T8270 243-245 FW denotes de
T8271 246-250 FW denotes novo
T8272 251-260 NN denotes synthesis
T8273 261-263 IN denotes of
T8274 264-275 NN denotes glutathione
T8275 276-277 -LRB- denotes (
T8276 277-279 CD denotes 45
T8277 279-280 -RRB- denotes )
T8278 280-281 : denotes ;
T8279 282-293 NN denotes glutathione
T8280 294-303 NN denotes reductase
T8281 304-305 CD denotes 1
T8282 306-307 -LRB- denotes (
T8283 307-310 NN denotes Gsr
T8284 310-311 -RRB- denotes )
T8285 311-313 , denotes ,
T8286 313-316 DT denotes the
T8287 326-332 NN denotes enzyme
T8288 317-325 VBG denotes reducing
T8289 333-336 IN denotes for
T8290 337-345 VBN denotes oxidized
T8291 346-357 NN denotes glutathione
T8292 358-359 -LRB- denotes (
T8293 359-361 CD denotes 45
T8294 361-362 -RRB- denotes )
T8295 362-363 : denotes ;
T8296 364-367 CC denotes and
T8297 368-379 NN denotes glutathione
T8298 382-393 NN denotes transferase
T8299 379-380 HYPH denotes -
T8300 380-381 NN denotes S
T8301 381-382 HYPH denotes -
T8302 393-395 , denotes ,
T8303 395-397 NN denotes mu
T8304 401-406 NN denotes Gstm4
T8305 398-399 CD denotes 4
T8306 400-401 -LRB- denotes (
T8307 406-407 -RRB- denotes )
T8308 407-409 , denotes ,
T8309 409-414 WDT denotes which
T8310 415-417 VBZ denotes is
T8311 418-419 DT denotes a
T8312 420-426 NN denotes member
T8313 427-429 IN denotes of
T8314 430-433 DT denotes the
T8315 470-476 NN denotes family
T8316 434-445 NN denotes glutathione
T8317 448-459 NN denotes transferase
T8318 445-446 HYPH denotes -
T8319 446-447 NN denotes S
T8320 447-448 HYPH denotes -
T8321 460-469 NN denotes supergene
T8322 477-479 IN denotes of
T8323 480-494 NN denotes detoxification
T8324 495-502 NNS denotes enzymes
T8325 503-504 -LRB- denotes (
T8326 504-506 CD denotes 45
T8327 506-507 -RRB- denotes )
T8328 507-508 . denotes .
R5145 T8229 T8230 amod Several,genes
R5146 T8230 T8231 nsubjpass genes,found
R5147 T8232 T8230 acl involved,genes
R5148 T8233 T8232 prep in,involved
R5149 T8234 T8235 det the,metabolism
R5150 T8235 T8233 pobj metabolism,in
R5151 T8236 T8235 prep of,metabolism
R5152 T8237 T8238 det the,glutathione
R5153 T8238 T8236 pobj glutathione,of
R5154 T8239 T8238 compound antioxidant,glutathione
R5155 T8240 T8231 auxpass were,found
R5156 T8241 T8242 aux to,upregulated
R5157 T8242 T8231 xcomp upregulated,found
R5158 T8243 T8242 auxpass be,upregulated
R5159 T8244 T8242 agent by,upregulated
R5160 T8245 T8246 compound cadmium,exposure
R5161 T8246 T8244 pobj exposure,by
R5162 T8247 T8242 punct ", ",upregulated
R5163 T8248 T8249 advmod namely,genes
R5164 T8249 T8242 dobj genes,upregulated
R5165 T8250 T8249 det the,genes
R5166 T8251 T8249 acl encoding,genes
R5167 T8252 T8253 det the,subunit
R5168 T8253 T8251 dobj subunit,encoding
R5169 T8254 T8253 amod catalytic,subunit
R5170 T8255 T8253 prep of,subunit
R5171 T8256 T8257 compound glutamate,ligase
R5172 T8257 T8255 pobj ligase,of
R5173 T8258 T8257 punct -,ligase
R5174 T8259 T8257 compound cysteine,ligase
R5175 T8260 T8253 punct (,subunit
R5176 T8261 T8253 appos Gclc,subunit
R5177 T8262 T8253 punct ),subunit
R5178 T8263 T8264 dep that,is
R5179 T8264 T8253 relcl is,subunit
R5180 T8265 T8266 det the,enzyme
R5181 T8266 T8264 attr enzyme,is
R5182 T8267 T8268 npadvmod rate,limiting
R5183 T8268 T8266 amod limiting,enzyme
R5184 T8269 T8266 prep in,enzyme
R5185 T8270 T8271 advmod de,novo
R5186 T8271 T8272 amod novo,synthesis
R5187 T8272 T8269 pobj synthesis,in
R5188 T8273 T8272 prep of,synthesis
R5189 T8274 T8273 pobj glutathione,of
R5190 T8275 T8276 punct (,45
R5191 T8276 T8264 parataxis 45,is
R5192 T8277 T8276 punct ),45
R5193 T8278 T8249 punct ;,genes
R5194 T8279 T8280 compound glutathione,reductase
R5195 T8280 T8249 conj reductase,genes
R5196 T8281 T8280 nummod 1,reductase
R5197 T8282 T8280 punct (,reductase
R5198 T8283 T8280 appos Gsr,reductase
R5199 T8284 T8280 punct ),reductase
R5200 T8285 T8280 punct ", ",reductase
R5201 T8286 T8287 det the,enzyme
R5202 T8287 T8280 appos enzyme,reductase
R5203 T8288 T8287 amod reducing,enzyme
R5204 T8289 T8287 prep for,enzyme
R5205 T8290 T8291 amod oxidized,glutathione
R5206 T8291 T8289 pobj glutathione,for
R5207 T8292 T8293 punct (,45
R5208 T8293 T8291 parataxis 45,glutathione
R5209 T8294 T8293 punct ),45
R5210 T8295 T8280 punct ;,reductase
R5211 T8296 T8280 cc and,reductase
R5212 T8297 T8298 compound glutathione,transferase
R5213 T8298 T8280 conj transferase,reductase
R5214 T8299 T8298 punct -,transferase
R5215 T8300 T8298 compound S,transferase
R5216 T8301 T8298 punct -,transferase
R5217 T8302 T8298 punct ", ",transferase
R5218 T8303 T8304 nmod mu,Gstm4
R5219 T8304 T8298 appos Gstm4,transferase
R5220 T8305 T8304 nummod 4,Gstm4
R5221 T8306 T8304 punct (,Gstm4
R5222 T8307 T8304 punct ),Gstm4
R5223 T8308 T8298 punct ", ",transferase
R5224 T8309 T8310 dep which,is
R5225 T8310 T8298 relcl is,transferase
R5226 T8311 T8312 det a,member
R5227 T8312 T8310 attr member,is
R5228 T8313 T8312 prep of,member
R5229 T8314 T8315 det the,family
R5230 T8315 T8313 pobj family,of
R5231 T8316 T8317 compound glutathione,transferase
R5232 T8317 T8315 compound transferase,family
R5233 T8318 T8317 punct -,transferase
R5234 T8319 T8317 compound S,transferase
R5235 T8320 T8317 punct -,transferase
R5236 T8321 T8315 compound supergene,family
R5237 T8322 T8315 prep of,family
R5238 T8323 T8324 compound detoxification,enzymes
R5239 T8324 T8322 pobj enzymes,of
R5240 T8325 T8326 punct (,45
R5241 T8326 T8312 parataxis 45,member
R5242 T8327 T8326 punct ),45
R5243 T8328 T8231 punct .,found

2_test

Id Subject Object Predicate Lexical cue
16221973-14988435-77403437 277-279 14988435 denotes 45
16221973-14988435-77403438 359-361 14988435 denotes 45
16221973-14988435-77403439 504-506 14988435 denotes 45

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T7905 9-14 SO:0000704 denotes genes
T7906 31-44 _FRAGMENT denotes metabolism of
T7907 61-72 GO:0006749 denotes glutathione
T7908 61-72 CHEBI:16856 denotes glutathione
T7909 134-139 SO:0000704 denotes genes
T7910 153-199 PR:000007897 denotes catalytic subunit of glutamate-cysteine ligase
T7911 201-205 PR:000007897 denotes Gclc
T7912 251-275 GO:0006750 denotes synthesis of glutathione
T7913 264-275 CHEBI:16856 denotes glutathione
T7914 282-293 CHEBI:16856 denotes glutathione
T7915 282-305 PR:000008292 denotes glutathione reductase 1
T7916 317-325 MOP:0000569 denotes reducing
T7917 337-345 MOP:0000568 denotes oxidized
T7918 337-357 CHEBI:17858 denotes oxidized glutathione
T7919 368-379 CHEBI:16856 denotes glutathione
T7920 368-399 PR:000030257 denotes glutathione-S-transferase, mu 4
T7921 401-406 PR:000030257 denotes Gstm4
T7922 434-445 CHEBI:16856 denotes glutathione
T7923 480-494 GO:0098754 denotes detoxification
R5029 T7907 T7906 _lexicallyChainedTo glutathione,metabolism of

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T7990 9-14 SO_EXT:0000704 denotes genes
T7991 31-44 _FRAGMENT denotes metabolism of
T7992 61-72 GO:0006749 denotes glutathione
T7993 49-60 CHEBI_GO_EXT:antioxidant denotes antioxidant
T7994 53-60 CHEBI_MOP_EXT:oxidising_agent_or_oxidation denotes oxidant
T7995 61-72 CHEBI:16856 denotes glutathione
T7996 90-101 GO_EXT:positive_regulation denotes upregulated
T7997 105-112 CHEBI_EXT:cadmium denotes cadmium
T7998 134-139 SO_EXT:0000704 denotes genes
T7999 140-148 SO_EXT:sequence_coding_function denotes encoding
T8000 153-162 GO_MOP_EXT:catalysis denotes catalytic
T8001 153-199 PR_EXT:000007897 denotes catalytic subunit of glutamate-cysteine ligase
T8002 174-183 CHEBI_EXT:glutamate denotes glutamate
T8003 174-199 GO_EXT:0004357 denotes glutamate-cysteine ligase
T8004 184-192 CHEBI_SO_EXT:cysteine denotes cysteine
T8005 201-205 PR_EXT:000007897 denotes Gclc
T8006 201-205 GO_EXT:0004357 denotes Gclc
T8007 233-239 CHEBI_GO_SO_EXT:enzyme denotes enzyme
T8008 251-275 GO:0006750 denotes synthesis of glutathione
T8009 264-275 CHEBI:16856 denotes glutathione
T8010 282-293 CHEBI:16856 denotes glutathione
T8011 282-303 GO_PR_EXT:glutathione_disulfide_reductase denotes glutathione reductase
T8012 282-305 PR_EXT:000008292 denotes glutathione reductase 1
T8013 307-310 GO_PR_EXT:glutathione_disulfide_reductase denotes Gsr
T8014 317-325 MOP:0000569 denotes reducing
T8015 326-332 CHEBI_GO_SO_EXT:enzyme denotes enzyme
T8016 337-345 MOP:0000568 denotes oxidized
T8017 337-357 CHEBI:17858 denotes oxidized glutathione
T8018 368-379 CHEBI:16856 denotes glutathione
T8019 368-393 GO_PR_EXT:glutathione_S_transferase denotes glutathione-S-transferase
T8020 368-399 PR_EXT:000030257 denotes glutathione-S-transferase, mu 4
T8021 380-381 CHEBI_EXT:sulfur denotes S
T8022 401-406 PR_EXT:000030257 denotes Gstm4
T8023 434-445 CHEBI:16856 denotes glutathione
T8024 434-459 GO_PR_EXT:glutathione_S_transferase denotes glutathione-S-transferase
T8025 446-447 CHEBI_EXT:sulfur denotes S
T8026 480-494 GO:0098754 denotes detoxification
T8027 495-502 CHEBI_GO_SO_EXT:enzyme denotes enzymes
R5031 T7992 T7991 _lexicallyChainedTo glutathione,metabolism of