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RT–PCRs confirmed the microarray results, namely, that Csrp1 expression is elevated in Mtf1loxP livers upon cadmium exposure (Figure 4a). 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{"project":"craft-ca-core-dev","denotations":[{"id":"T7163","span":{"begin":72,"end":77},"obj":"PR:000005958"},{"id":"T7164","span":{"begin":78,"end":88},"obj":"GO:0010467"},{"id":"T7165","span":{"begin":104,"end":108},"obj":"PR:000010717"},{"id":"T7166","span":{"begin":108,"end":112},"obj":"SO:0000346"},{"id":"T7167","span":{"begin":113,"end":119},"obj":"UBERON:0002107"},{"id":"T7168","span":{"begin":206,"end":212},"obj":"UBERON:0002107"},{"id":"T7169","span":{"begin":218,"end":222},"obj":"PR:000010717"},{"id":"T7170","span":{"begin":222,"end":224},"obj":"PR:000010788"},{"id":"T7171","span":{"begin":229,"end":233},"obj":"NCBITaxon:10088"},{"id":"T7172","span":{"begin":251,"end":256},"obj":"PR:000010717"},{"id":"T7173","span":{"begin":294,"end":299},"obj":"PR:000005958"}],"text":"Semiquantitative RT–PCRs confirmed the microarray results, namely, that Csrp1 expression is elevated in Mtf1loxP livers upon cadmium exposure (Figure 4a). In contrast, no cadmium response was detectable in livers from Mtf1Mx-cre mice, suggesting that MTF-1 is required for cadmium induction of Csrp1."}

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