PMC:1253828 / 19545-20119 JSONTXT

Annnotations TAB JSON ListView MergeView

    craft-sa-dev

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all MTF-1 target genes characterized so far, such as Mt1, Mt2 and Znt1, MTF-1 exerts its transcriptional activation activity via standard MRE sequences located proximal to the transcription start (4,5,8,18,19). Even a specific search for MTF-1 binding sites by selection from a pool of double-stranded oligonucleotides with random sequences yielded no new binding motif for MTF-1 in addition to the known MREs (34). Thus, an MRE sequence is to date the only indication for a direct MTF-1 target gene, and four MRE-containing target gene candidates were further analyzed."}

    2_test

    {"project":"2_test","denotations":[{"id":"16221973-8026472-77403425","span":{"begin":201,"end":202},"obj":"8026472"},{"id":"16221973-8824273-77403426","span":{"begin":203,"end":204},"obj":"8824273"},{"id":"16221973-6095286-77403427","span":{"begin":205,"end":206},"obj":"6095286"},{"id":"16221973-10096565-77403428","span":{"begin":207,"end":209},"obj":"10096565"},{"id":"16221973-10952993-77403429","span":{"begin":210,"end":212},"obj":"10952993"},{"id":"16221973-15318811-77403430","span":{"begin":415,"end":417},"obj":"15318811"}],"text":"For all MTF-1 target genes characterized so far, such as Mt1, Mt2 and Znt1, MTF-1 exerts its transcriptional activation activity via standard MRE sequences located proximal to the transcription start (4,5,8,18,19). Even a specific search for MTF-1 binding sites by selection from a pool of double-stranded oligonucleotides with random sequences yielded no new binding motif for MTF-1 in addition to the known MREs (34). Thus, an MRE sequence is to date the only indication for a direct MTF-1 target gene, and four MRE-containing target gene candidates were further analyzed."}

    craft-ca-core-dev

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    craft-ca-core-ex-dev

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