PMC:1253828 / 1528-1778 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1253828","sourcedb":"PMC","sourceid":"1253828","source_url":"http://www.ncbi.nlm.nih.gov/pmc/1253828","text":"ved in the synthesis and regeneration of glutathione, a cadmium-binding antioxidant. These data provide strong evidence for two major branches of cellular anti-cadmium defense, one via MTF-1 and its target genes, notably metallothioneins, the other v","tracks":[{"project":"craft-sa-dev","denotations":[{"id":"T539","span":{"begin":4,"end":6},"obj":"IN"},{"id":"T540","span":{"begin":7,"end":10},"obj":"DT"},{"id":"T541","span":{"begin":11,"end":20},"obj":"NN"},{"id":"T542","span":{"begin":21,"end":24},"obj":"CC"},{"id":"T543","span":{"begin":25,"end":37},"obj":"NN"},{"id":"T544","span":{"begin":38,"end":40},"obj":"IN"},{"id":"T545","span":{"begin":41,"end":52},"obj":"NN"},{"id":"T546","span":{"begin":52,"end":54},"obj":","},{"id":"T547","span":{"begin":54,"end":55},"obj":"DT"},{"id":"T548","span":{"begin":72,"end":83},"obj":"NN"},{"id":"T549","span":{"begin":56,"end":63},"obj":"NN"},{"id":"T550","span":{"begin":64,"end":71},"obj":"VBG"},{"id":"T551","span":{"begin":63,"end":64},"obj":"HYPH"},{"id":"T552","span":{"begin":83,"end":84},"obj":"."},{"id":"T554","span":{"begin":85,"end":90},"obj":"DT"},{"id":"T555","span":{"begin":91,"end":95},"obj":"NNS"},{"id":"T556","span":{"begin":96,"end":103},"obj":"VBP"},{"id":"T557","span":{"begin":104,"end":110},"obj":"JJ"},{"id":"T558","span":{"begin":111,"end":119},"obj":"NN"},{"id":"T559","span":{"begin":120,"end":123},"obj":"IN"},{"id":"T560","span":{"begin":124,"end":127},"obj":"CD"},{"id":"T561","span":{"begin":134,"end":142},"obj":"NNS"},{"id":"T562","span":{"begin":128,"end":133},"obj":"JJ"},{"id":"T563","span":{"begin":143,"end":145},"obj":"IN"},{"id":"T564","span":{"begin":146,"end":154},"obj":"JJ"},{"id":"T565","span":{"begin":168,"end":175},"obj":"NN"},{"id":"T566","span":{"begin":155,"end":167},"obj":"JJ"},{"id":"T567","span":{"begin":175,"end":177},"obj":","},{"id":"T568","span":{"begin":177,"end":180},"obj":"CD"},{"id":"T569","span":{"begin":181,"end":184},"obj":"IN"},{"id":"T570","span":{"begin":185,"end":188},"obj":"NN"},{"id":"T571","span":{"begin":188,"end":189},"obj":"HYPH"},{"id":"T572","span":{"begin":189,"end":190},"obj":"CD"},{"id":"T573","span":{"begin":191,"end":194},"obj":"CC"},{"id":"T574","span":{"begin":195,"end":198},"obj":"PRP$"},{"id":"T575","span":{"begin":206,"end":211},"obj":"NNS"},{"id":"T576","span":{"begin":199,"end":205},"obj":"NN"},{"id":"T577","span":{"begin":211,"end":213},"obj":","},{"id":"T578","span":{"begin":213,"end":220},"obj":"RB"},{"id":"T579","span":{"begin":221,"end":237},"obj":"NNS"},{"id":"T580","span":{"begin":237,"end":239},"obj":","},{"id":"T581","span":{"begin":239,"end":242},"obj":"DT"},{"id":"T582","span":{"begin":243,"end":248},"obj":"JJ"}],"relations":[{"id":"R284","pred":"det","subj":"T540","obj":"T541"},{"id":"R285","pred":"pobj","subj":"T541","obj":"T539"},{"id":"R286","pred":"cc","subj":"T542","obj":"T541"},{"id":"R287","pred":"conj","subj":"T543","obj":"T541"},{"id":"R288","pred":"prep","subj":"T544","obj":"T541"},{"id":"R289","pred":"pobj","subj":"T545","obj":"T544"},{"id":"R290","pred":"punct","subj":"T546","obj":"T545"},{"id":"R291","pred":"det","subj":"T547","obj":"T548"},{"id":"R292","pred":"appos","subj":"T548","obj":"T545"},{"id":"R293","pred":"npadvmod","subj":"T549","obj":"T550"},{"id":"R294","pred":"amod","subj":"T550","obj":"T548"},{"id":"R295","pred":"punct","subj":"T551","obj":"T550"},{"id":"R297","pred":"det","subj":"T554","obj":"T555"},{"id":"R298","pred":"nsubj","subj":"T555","obj":"T556"},{"id":"R299","pred":"amod","subj":"T557","obj":"T558"},{"id":"R300","pred":"dobj","subj":"T558","obj":"T556"},{"id":"R301","pred":"prep","subj":"T559","obj":"T558"},{"id":"R302","pred":"nummod","subj":"T560","obj":"T561"},{"id":"R303","pred":"pobj","subj":"T561","obj":"T559"},{"id":"R304","pred":"amod","subj":"T562","obj":"T561"},{"id":"R305","pred":"prep","subj":"T563","obj":"T561"},{"id":"R306","pred":"amod","subj":"T564","obj":"T565"},{"id":"R307","pred":"pobj","subj":"T565","obj":"T563"},{"id":"R308","pred":"amod","subj":"T566","obj":"T565"},{"id":"R309","pred":"punct","subj":"T567","obj":"T561"},{"id":"R310","pred":"appos","subj":"T568","obj":"T561"},{"id":"R311","pred":"prep","subj":"T569","obj":"T568"},{"id":"R312","pred":"pobj","subj":"T570","obj":"T569"},{"id":"R313","pred":"punct","subj":"T571","obj":"T570"},{"id":"R314","pred":"nummod","subj":"T572","obj":"T570"},{"id":"R315","pred":"cc","subj":"T573","obj":"T570"},{"id":"R316","pred":"poss","subj":"T574","obj":"T575"},{"id":"R317","pred":"conj","subj":"T575","obj":"T570"},{"id":"R318","pred":"compound","subj":"T576","obj":"T575"},{"id":"R319","pred":"punct","subj":"T577","obj":"T575"},{"id":"R320","pred":"advmod","subj":"T578","obj":"T579"},{"id":"R321","pred":"appos","subj":"T579","obj":"T575"},{"id":"R322","pred":"punct","subj":"T580","obj":"T568"},{"id":"R323","pred":"det","subj":"T581","obj":"T582"},{"id":"R324","pred":"appos","subj":"T582","obj":"T568"}],"attributes":[{"subj":"T539","pred":"source","obj":"craft-sa-dev"},{"subj":"T540","pred":"source","obj":"craft-sa-dev"},{"subj":"T541","pred":"source","obj":"craft-sa-dev"},{"subj":"T542","pred":"source","obj":"craft-sa-dev"},{"subj":"T543","pred":"source","obj":"craft-sa-dev"},{"subj":"T544","pred":"source","obj":"craft-sa-dev"},{"subj":"T545","pred":"source","obj":"craft-sa-dev"},{"subj":"T546","pred":"source","obj":"craft-sa-dev"},{"subj":"T547","pred":"source","obj":"craft-sa-dev"},{"subj":"T548","pred":"source","obj":"craft-sa-dev"},{"subj":"T549","pred":"source","obj":"craft-sa-dev"},{"subj":"T550","pred":"source","obj":"craft-sa-dev"},{"subj":"T551","pred":"source","obj":"craft-sa-dev"},{"subj":"T552","pred":"source","obj":"craft-sa-dev"},{"subj":"T554","pred":"source","obj":"craft-sa-dev"},{"subj":"T555","pred":"source","obj":"craft-sa-dev"},{"subj":"T556","pred":"source","obj":"craft-sa-dev"},{"subj":"T557","pred":"source","obj":"craft-sa-dev"},{"subj":"T558","pred":"source","obj":"craft-sa-dev"},{"subj":"T559","pred":"source","obj":"craft-sa-dev"},{"subj":"T560","pred":"source","obj":"craft-sa-dev"},{"subj":"T561","pred":"source","obj":"craft-sa-dev"},{"subj":"T562","pred":"source","obj":"craft-sa-dev"},{"subj":"T563","pred":"source","obj":"craft-sa-dev"},{"subj":"T564","pred":"source","obj":"craft-sa-dev"},{"subj":"T565","pred":"source","obj":"craft-sa-dev"},{"subj":"T566","pred":"source","obj":"craft-sa-dev"},{"subj":"T567","pred":"source","obj":"craft-sa-dev"},{"subj":"T568","pred":"source","obj":"craft-sa-dev"},{"subj":"T569","pred":"source","obj":"craft-sa-dev"},{"subj":"T570","pred":"source","obj":"craft-sa-dev"},{"subj":"T571","pred":"source","obj":"craft-sa-dev"},{"subj":"T572","pred":"source","obj":"craft-sa-dev"},{"subj":"T573","pred":"source","obj":"craft-sa-dev"},{"subj":"T574","pred":"source","obj":"craft-sa-dev"},{"subj":"T575","pred":"source","obj":"craft-sa-dev"},{"subj":"T576","pred":"source","obj":"craft-sa-dev"},{"subj":"T577","pred":"source","obj":"craft-sa-dev"},{"subj":"T578","pred":"source","obj":"craft-sa-dev"},{"subj":"T579","pred":"source","obj":"craft-sa-dev"},{"subj":"T580","pred":"source","obj":"craft-sa-dev"},{"subj":"T581","pred":"source","obj":"craft-sa-dev"},{"subj":"T582","pred":"source","obj":"craft-sa-dev"}]},{"project":"craft-ca-core-dev","denotations":[{"id":"T131","span":{"begin":11,"end":20},"obj":"_FRAGMENT"},{"id":"T132","span":{"begin":38,"end":52},"obj":"GO:0006750"},{"id":"T133","span":{"begin":41,"end":52},"obj":"CHEBI:16856"},{"id":"T134","span":{"begin":146,"end":154},"obj":"_FRAGMENT"},{"id":"T135","span":{"begin":168,"end":175},"obj":"GO:0006968"},{"id":"T136","span":{"begin":185,"end":190},"obj":"PR:000010717"},{"id":"T137","span":{"begin":206,"end":211},"obj":"SO:0000704"}],"relations":[{"id":"R2","pred":"_lexicallyChainedTo","subj":"T132","obj":"T131"},{"id":"R3","pred":"_lexicallyChainedTo","subj":"T135","obj":"T134"}],"attributes":[{"subj":"T131","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T132","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T133","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T134","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T135","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T136","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T137","pred":"source","obj":"craft-ca-core-dev"}]},{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T223","span":{"begin":11,"end":20},"obj":"_FRAGMENT"},{"id":"T224","span":{"begin":38,"end":52},"obj":"GO:0006750"},{"id":"T225","span":{"begin":41,"end":52},"obj":"CHEBI:16856"},{"id":"T226","span":{"begin":56,"end":63},"obj":"CHEBI_EXT:cadmium"},{"id":"T227","span":{"begin":64,"end":71},"obj":"CHEMINF_GO_EXT:chemical_binding_or_bond_formation"},{"id":"T228","span":{"begin":72,"end":83},"obj":"CHEBI_GO_EXT:antioxidant"},{"id":"T229","span":{"begin":76,"end":83},"obj":"CHEBI_MOP_EXT:oxidising_agent_or_oxidation"},{"id":"T230","span":{"begin":146,"end":154},"obj":"CL_GO_EXT:cell"},{"id":"T231","span":{"begin":146,"end":154},"obj":"_FRAGMENT"},{"id":"T232","span":{"begin":168,"end":175},"obj":"GO:0006968"},{"id":"T233","span":{"begin":160,"end":167},"obj":"CHEBI_EXT:cadmium"},{"id":"T234","span":{"begin":185,"end":190},"obj":"PR_EXT:000010717"},{"id":"T235","span":{"begin":206,"end":211},"obj":"SO_EXT:0000704"}],"relations":[{"id":"R5","pred":"_lexicallyChainedTo","subj":"T224","obj":"T223"},{"id":"R6","pred":"_lexicallyChainedTo","subj":"T232","obj":"T231"}],"attributes":[{"subj":"T223","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T224","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T225","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T226","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T227","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T228","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T229","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T230","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T231","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T232","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T233","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T234","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T235","pred":"source","obj":"craft-ca-core-ex-dev"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"craft-sa-dev","color":"#ecea93","default":true},{"id":"craft-ca-core-dev","color":"#d093ec"},{"id":"craft-ca-core-ex-dev","color":"#93ecb6"}]}]}}