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Id Subject Object Predicate Lexical cue
T2344 0-5 NN denotes Yeast
T2345 17-26 NN denotes screening
T2346 6-9 CD denotes two
T2347 10-16 NN denotes hybrid
T2348 9-10 HYPH denotes -
T2349 26-323 sentence denotes We hypothesised that the C-terminal peptide might be involved in protein-protein interactions, and we tested this by screening a cDNA library using the yeast two-hybrid system with a construct (PAX6CTP) in which the 32 amino acid C-terminal peptide was fused to the yeast GAL4 DNA binding domain.
T2350 27-29 PRP denotes We
T2351 30-42 VBD denotes hypothesised
T2352 43-47 IN denotes that
T2353 80-88 VBN denotes involved
T2354 48-51 DT denotes the
T2355 63-70 NN denotes peptide
T2356 52-53 NN denotes C
T2357 54-62 JJ denotes terminal
T2358 53-54 HYPH denotes -
T2359 71-76 MD denotes might
T2360 77-79 VB denotes be
T2361 89-91 IN denotes in
T2362 92-99 NN denotes protein
T2363 100-107 NN denotes protein
T2364 99-100 SYM denotes -
T2365 108-120 NNS denotes interactions
T2366 120-122 , denotes ,
T2367 122-125 CC denotes and
T2368 126-128 PRP denotes we
T2369 129-135 VBD denotes tested
T2370 136-140 DT denotes this
T2371 141-143 IN denotes by
T2372 144-153 VBG denotes screening
T2373 154-155 DT denotes a
T2374 161-168 NN denotes library
T2375 156-160 NN denotes cDNA
T2376 169-174 VBG denotes using
T2377 175-178 DT denotes the
T2378 196-202 NN denotes system
T2379 179-184 NN denotes yeast
T2380 185-188 CD denotes two
T2381 189-195 NN denotes hybrid
T2382 188-189 HYPH denotes -
T2383 203-207 IN denotes with
T2384 208-209 DT denotes a
T2385 210-219 NN denotes construct
T2386 220-221 -LRB- denotes (
T2387 221-228 NN denotes PAX6CTP
T2388 228-229 -RRB- denotes )
T2389 230-232 IN denotes in
T2390 280-285 VBN denotes fused
T2391 233-238 WDT denotes which
T2392 239-242 DT denotes the
T2393 268-275 NN denotes peptide
T2394 243-245 CD denotes 32
T2395 252-256 NN denotes acid
T2396 246-251 NN denotes amino
T2397 257-258 NN denotes C
T2398 259-267 JJ denotes terminal
T2399 258-259 HYPH denotes -
T2400 276-279 VBD denotes was
T2401 286-288 IN denotes to
T2402 289-292 DT denotes the
T2403 316-322 NN denotes domain
T2404 293-298 NN denotes yeast
T2405 299-303 NN denotes GAL4
T2406 304-307 NN denotes DNA
T2407 308-315 NN denotes binding
T2408 322-323 . denotes .
T2409 323-407 sentence denotes We chose to screen a mouse brain cDNA library as no human libraries were available.
T2410 324-326 PRP denotes We
T2411 327-332 VBD denotes chose
T2412 333-335 TO denotes to
T2413 336-342 VB denotes screen
T2414 343-344 DT denotes a
T2415 362-369 NN denotes library
T2416 345-350 NN denotes mouse
T2417 351-356 NN denotes brain
T2418 357-361 NN denotes cDNA
T2419 370-372 IN denotes as
T2420 392-396 VBD denotes were
T2421 373-375 DT denotes no
T2422 382-391 NNS denotes libraries
T2423 376-381 JJ denotes human
T2424 397-406 JJ denotes available
T2425 406-407 . denotes .
T2426 407-575 sentence denotes Given the fact that the amino acid sequence of the PAX6 protein is identical in man and mouse, we reasoned that a mouse brain library would yield relevant interactors.
T2427 408-413 VBN denotes Given
T2428 506-514 VBD denotes reasoned
T2429 414-417 DT denotes the
T2430 418-422 NN denotes fact
T2431 423-427 IN denotes that
T2432 472-474 VBZ denotes is
T2433 428-431 DT denotes the
T2434 443-451 NN denotes sequence
T2435 432-437 NN denotes amino
T2436 438-442 NN denotes acid
T2437 452-454 IN denotes of
T2438 455-458 DT denotes the
T2439 464-471 NN denotes protein
T2440 459-463 NN denotes PAX6
T2441 475-484 JJ denotes identical
T2442 485-487 IN denotes in
T2443 488-491 NN denotes man
T2444 492-495 CC denotes and
T2445 496-501 NN denotes mouse
T2446 501-503 , denotes ,
T2447 503-505 PRP denotes we
T2448 515-519 IN denotes that
T2449 548-553 VB denotes yield
T2450 520-521 DT denotes a
T2451 534-541 NN denotes library
T2452 522-527 NN denotes mouse
T2453 528-533 NN denotes brain
T2454 542-547 MD denotes would
T2455 554-562 JJ denotes relevant
T2456 563-574 NNS denotes interactors
T2457 574-575 . denotes .
T2458 575-682 sentence denotes For comparison we also carried out the screen using a construct containing the whole PST domain (PAX6PST).
T2459 576-579 IN denotes For
T2460 599-606 VBD denotes carried
T2461 580-590 NN denotes comparison
T2462 591-593 PRP denotes we
T2463 594-598 RB denotes also
T2464 607-610 RP denotes out
T2465 611-614 DT denotes the
T2466 615-621 NN denotes screen
T2467 622-627 VBG denotes using
T2468 628-629 DT denotes a
T2469 630-639 NN denotes construct
T2470 640-650 VBG denotes containing
T2471 651-654 DT denotes the
T2472 665-671 NN denotes domain
T2473 655-660 JJ denotes whole
T2474 661-664 NN denotes PST
T2475 672-673 -LRB- denotes (
T2476 673-680 NN denotes PAX6PST
T2477 680-681 -RRB- denotes )
T2478 681-682 . denotes .
T2479 682-817 sentence denotes The C-terminal peptide screen gave 15 colonies that were positive with all three reporters and the PST domain screen gave 62 colonies.
T2480 683-686 DT denotes The
T2481 706-712 NN denotes screen
T2482 687-688 NN denotes C
T2483 689-697 JJ denotes terminal
T2484 688-689 HYPH denotes -
T2485 698-705 NN denotes peptide
T2486 713-717 VBD denotes gave
T2487 718-720 CD denotes 15
T2488 721-729 NNS denotes colonies
T2489 730-734 WDT denotes that
T2490 735-739 VBD denotes were
T2491 740-748 JJ denotes positive
T2492 749-753 IN denotes with
T2493 754-757 DT denotes all
T2494 764-773 NNS denotes reporters
T2495 758-763 CD denotes three
T2496 774-777 CC denotes and
T2497 778-781 DT denotes the
T2498 793-799 NN denotes screen
T2499 782-785 NN denotes PST
T2500 786-792 NN denotes domain
T2501 800-804 VBD denotes gave
T2502 805-807 CD denotes 62
T2503 808-816 NNS denotes colonies
T2504 816-817 . denotes .
T2505 817-888 sentence denotes The interacting plasmids were isolated and the cDNA inserts sequenced.
T2506 818-821 DT denotes The
T2507 834-842 NNS denotes plasmids
T2508 822-833 VBG denotes interacting
T2509 848-856 VBN denotes isolated
T2510 843-847 VBD denotes were
T2511 857-860 CC denotes and
T2512 861-864 DT denotes the
T2513 870-877 NNS denotes inserts
T2514 865-869 NN denotes cDNA
T2515 878-887 VBN denotes sequenced
T2516 887-888 . denotes .
T2517 888-1099 sentence denotes Three cDNAs were identified 3 or more times, Homer3 (NM_011984), Dncl1 (Dynein cytoplasmic light chain 1, NM_019682, also known as Pin or Dlc8) and Trim11 (Tripartite motif protein family member 11, NM_053168).
T2518 889-894 CD denotes Three
T2519 895-900 NNS denotes cDNAs
T2520 906-916 VBN denotes identified
T2521 901-905 VBD denotes were
T2522 917-918 CD denotes 3
T2523 927-932 NNS denotes times
T2524 919-921 CC denotes or
T2525 922-926 JJR denotes more
T2526 932-934 , denotes ,
T2527 934-940 NN denotes Homer3
T2528 941-942 -LRB- denotes (
T2529 942-951 NN denotes NM_011984
T2530 951-952 -RRB- denotes )
T2531 952-954 , denotes ,
T2532 954-959 NN denotes Dncl1
T2533 960-961 -LRB- denotes (
T2534 961-967 NNP denotes Dynein
T2535 986-991 NN denotes chain
T2536 968-979 JJ denotes cytoplasmic
T2537 980-985 JJ denotes light
T2538 992-993 CD denotes 1
T2539 993-995 , denotes ,
T2540 995-1004 NN denotes NM_019682
T2541 1004-1006 , denotes ,
T2542 1006-1010 RB denotes also
T2543 1011-1016 VBN denotes known
T2544 1017-1019 IN denotes as
T2545 1020-1023 NN denotes Pin
T2546 1024-1026 CC denotes or
T2547 1027-1031 NN denotes Dlc8
T2548 1031-1032 -RRB- denotes )
T2549 1033-1036 CC denotes and
T2550 1037-1043 NN denotes Trim11
T2551 1044-1045 -LRB- denotes (
T2552 1045-1055 JJ denotes Tripartite
T2553 1056-1061 NN denotes motif
T2554 1077-1083 NN denotes member
T2555 1062-1069 NN denotes protein
T2556 1070-1076 NN denotes family
T2557 1084-1086 CD denotes 11
T2558 1086-1088 , denotes ,
T2559 1088-1097 NN denotes NM_053168
T2560 1097-1098 -RRB- denotes )
T2561 1098-1099 . denotes .
T2562 1099-1188 sentence denotes Homer3 (6 clones) and Dncl1 (2 clones) were identified in the C-terminal peptide screen.
T2563 1100-1106 NN denotes Homer3
T2564 1144-1154 VBN denotes identified
T2565 1107-1108 -LRB- denotes (
T2566 1110-1116 NNS denotes clones
T2567 1108-1109 CD denotes 6
T2568 1116-1117 -RRB- denotes )
T2569 1118-1121 CC denotes and
T2570 1122-1127 NN denotes Dncl1
T2571 1128-1129 -LRB- denotes (
T2572 1131-1137 NNS denotes clones
T2573 1129-1130 CD denotes 2
T2574 1137-1138 -RRB- denotes )
T2575 1139-1143 VBD denotes were
T2576 1155-1157 IN denotes in
T2577 1158-1161 DT denotes the
T2578 1181-1187 NN denotes screen
T2579 1162-1163 NN denotes C
T2580 1164-1172 JJ denotes terminal
T2581 1163-1164 HYPH denotes -
T2582 1173-1180 NN denotes peptide
T2583 1187-1188 . denotes .
T2584 1188-1288 sentence denotes Homer3 (7 clones), Dncl1 (2 clones) and Trim11 (6 clones) were identified in the PST domain screen.
T2585 1189-1195 NN denotes Homer3
T2586 1252-1262 VBN denotes identified
T2587 1196-1197 -LRB- denotes (
T2588 1199-1205 NNS denotes clones
T2589 1197-1198 CD denotes 7
T2590 1205-1206 -RRB- denotes )
T2591 1206-1208 , denotes ,
T2592 1208-1213 NN denotes Dncl1
T2593 1214-1215 -LRB- denotes (
T2594 1217-1223 NNS denotes clones
T2595 1215-1216 CD denotes 2
T2596 1223-1224 -RRB- denotes )
T2597 1225-1228 CC denotes and
T2598 1229-1235 NN denotes Trim11
T2599 1236-1237 -LRB- denotes (
T2600 1239-1245 NNS denotes clones
T2601 1237-1238 CD denotes 6
T2602 1245-1246 -RRB- denotes )
T2603 1247-1251 VBD denotes were
T2604 1263-1265 IN denotes in
T2605 1266-1269 DT denotes the
T2606 1281-1287 NN denotes screen
T2607 1270-1273 NN denotes PST
T2608 1274-1280 NN denotes domain
T2609 1287-1288 . denotes .
T2610 1288-1379 sentence denotes All cDNA inserts were in-frame with the coding region of the pPC86 GAL4 activation domain.
T2611 1289-1292 DT denotes All
T2612 1298-1305 NNS denotes inserts
T2613 1293-1297 NN denotes cDNA
T2614 1306-1310 VBD denotes were
T2615 1311-1313 IN denotes in
T2616 1313-1314 HYPH denotes -
T2617 1314-1319 NN denotes frame
T2618 1320-1324 IN denotes with
T2619 1325-1328 DT denotes the
T2620 1336-1342 NN denotes region
T2621 1329-1335 NN denotes coding
T2622 1343-1345 IN denotes of
T2623 1346-1349 DT denotes the
T2624 1372-1378 NN denotes domain
T2625 1350-1355 NN denotes pPC86
T2626 1356-1360 NN denotes GAL4
T2627 1361-1371 NN denotes activation
T2628 1378-1379 . denotes .
T2629 1379-1450 sentence denotes None of the cDNAs was present in a list of known false positives [34].
T2630 1380-1384 NN denotes None
T2631 1398-1401 VBD denotes was
T2632 1385-1387 IN denotes of
T2633 1388-1391 DT denotes the
T2634 1392-1397 NNS denotes cDNAs
T2635 1402-1409 JJ denotes present
T2636 1410-1412 IN denotes in
T2637 1413-1414 DT denotes a
T2638 1415-1419 NN denotes list
T2639 1420-1422 IN denotes of
T2640 1423-1428 JJ denotes known
T2641 1435-1444 NNS denotes positives
T2642 1429-1434 JJ denotes false
T2643 1445-1446 -LRB- denotes [
T2644 1446-1448 CD denotes 34
T2645 1448-1449 -RRB- denotes ]
T2646 1449-1450 . denotes .
T2647 1450-1544 sentence denotes HOMER3 is a member of the HOMER family of neuronal post-synaptic density (PSD) proteins [35].
T2648 1451-1457 NN denotes HOMER3
T2649 1458-1460 VBZ denotes is
T2650 1461-1462 DT denotes a
T2651 1463-1469 NN denotes member
T2652 1470-1472 IN denotes of
T2653 1473-1476 DT denotes the
T2654 1483-1489 NN denotes family
T2655 1477-1482 NN denotes HOMER
T2656 1490-1492 IN denotes of
T2657 1493-1501 JJ denotes neuronal
T2658 1530-1538 NN denotes proteins
T2659 1502-1515 JJ denotes post-synaptic
T2660 1516-1523 NN denotes density
T2661 1524-1525 -LRB- denotes (
T2662 1525-1528 NN denotes PSD
T2663 1528-1529 -RRB- denotes )
T2664 1539-1540 -LRB- denotes [
T2665 1540-1542 CD denotes 35
T2666 1542-1543 -RRB- denotes ]
T2667 1543-1544 . denotes .
T2668 1544-1720 sentence denotes DNCL1 is a subunit of two motor protein complexes, dynein and myosin-Va, both of which are involved in intracellular trafficking of proteins and organelles in neurons [36,37].
T2669 1545-1550 NN denotes DNCL1
T2670 1551-1553 VBZ denotes is
T2671 1554-1555 DT denotes a
T2672 1556-1563 NN denotes subunit
T2673 1564-1566 IN denotes of
T2674 1567-1570 CD denotes two
T2675 1585-1594 NNS denotes complexes
T2676 1571-1576 NN denotes motor
T2677 1577-1584 NN denotes protein
T2678 1594-1596 , denotes ,
T2679 1596-1602 NN denotes dynein
T2680 1603-1606 CC denotes and
T2681 1607-1613 NN denotes myosin
T2682 1614-1616 NN denotes Va
T2683 1613-1614 HYPH denotes -
T2684 1616-1618 , denotes ,
T2685 1618-1622 DT denotes both
T2686 1636-1644 VBN denotes involved
T2687 1623-1625 IN denotes of
T2688 1626-1631 WDT denotes which
T2689 1632-1635 VBP denotes are
T2690 1645-1647 IN denotes in
T2691 1648-1661 JJ denotes intracellular
T2692 1662-1673 NN denotes trafficking
T2693 1674-1676 IN denotes of
T2694 1677-1685 NN denotes proteins
T2695 1686-1689 CC denotes and
T2696 1690-1700 NNS denotes organelles
T2697 1701-1703 IN denotes in
T2698 1704-1711 NNS denotes neurons
T2699 1712-1713 -LRB- denotes [
T2700 1716-1718 CD denotes 37
T2701 1713-1715 CD denotes 36
T2702 1715-1716 , denotes ,
T2703 1718-1719 -RRB- denotes ]
T2704 1719-1720 . denotes .
T2705 1720-1873 sentence denotes TRIM11 is a member of the tripartite motif protein family and contains a RING finger, a B-box zinc finger, a coiled coil domain and a B30.2 domain [38].
T2706 1721-1727 NN denotes TRIM11
T2707 1728-1730 VBZ denotes is
T2708 1731-1732 DT denotes a
T2709 1733-1739 NN denotes member
T2710 1740-1742 IN denotes of
T2711 1743-1746 DT denotes the
T2712 1772-1778 NN denotes family
T2713 1747-1757 JJ denotes tripartite
T2714 1758-1763 NN denotes motif
T2715 1764-1771 NN denotes protein
T2716 1779-1782 CC denotes and
T2717 1783-1791 VBZ denotes contains
T2718 1792-1793 DT denotes a
T2719 1799-1805 NN denotes finger
T2720 1794-1798 NN denotes RING
T2721 1805-1807 , denotes ,
T2722 1807-1808 DT denotes a
T2723 1820-1826 NN denotes finger
T2724 1809-1810 NN denotes B
T2725 1811-1814 NN denotes box
T2726 1810-1811 HYPH denotes -
T2727 1815-1819 NN denotes zinc
T2728 1826-1828 , denotes ,
T2729 1828-1829 DT denotes a
T2730 1842-1848 NN denotes domain
T2731 1830-1836 VBN denotes coiled
T2732 1837-1841 NN denotes coil
T2733 1849-1852 CC denotes and
T2734 1853-1854 DT denotes a
T2735 1861-1867 NN denotes domain
T2736 1855-1860 NN denotes B30.2
T2737 1868-1869 -LRB- denotes [
T2738 1869-1871 CD denotes 38
T2739 1871-1872 -RRB- denotes ]
T2740 1872-1873 . denotes .
T2741 1873-1971 sentence denotes The possible significance of the interactions between these proteins and PAX6 is discussed below.
T2742 1874-1877 DT denotes The
T2743 1887-1899 NN denotes significance
T2744 1878-1886 JJ denotes possible
T2745 1955-1964 VBN denotes discussed
T2746 1900-1902 IN denotes of
T2747 1903-1906 DT denotes the
T2748 1907-1919 NNS denotes interactions
T2749 1920-1927 IN denotes between
T2750 1928-1933 DT denotes these
T2751 1934-1942 NN denotes proteins
T2752 1943-1946 CC denotes and
T2753 1947-1951 NN denotes PAX6
T2754 1952-1954 VBZ denotes is
T2755 1965-1970 RB denotes below
T2756 1970-1971 . denotes .
R1365 T2344 T2345 nmod Yeast,screening
R1366 T2346 T2347 nummod two,hybrid
R1367 T2347 T2345 compound hybrid,screening
R1368 T2348 T2347 punct -,hybrid
R1369 T2350 T2351 nsubj We,hypothesised
R1370 T2352 T2353 mark that,involved
R1371 T2353 T2351 ccomp involved,hypothesised
R1372 T2354 T2355 det the,peptide
R1373 T2355 T2353 nsubjpass peptide,involved
R1374 T2356 T2357 npadvmod C,terminal
R1375 T2357 T2355 amod terminal,peptide
R1376 T2358 T2357 punct -,terminal
R1377 T2359 T2353 aux might,involved
R1378 T2360 T2353 auxpass be,involved
R1379 T2361 T2353 prep in,involved
R1380 T2362 T2363 nmod protein,protein
R1381 T2363 T2365 compound protein,interactions
R1382 T2364 T2363 punct -,protein
R1383 T2365 T2361 pobj interactions,in
R1384 T2366 T2351 punct ", ",hypothesised
R1385 T2367 T2351 cc and,hypothesised
R1386 T2368 T2369 nsubj we,tested
R1387 T2369 T2351 conj tested,hypothesised
R1388 T2370 T2369 dobj this,tested
R1389 T2371 T2369 prep by,tested
R1390 T2372 T2371 pcomp screening,by
R1391 T2373 T2374 det a,library
R1392 T2374 T2372 dobj library,screening
R1393 T2375 T2374 compound cDNA,library
R1394 T2376 T2372 advcl using,screening
R1395 T2377 T2378 det the,system
R1396 T2378 T2376 dobj system,using
R1397 T2379 T2378 nmod yeast,system
R1398 T2380 T2381 nummod two,hybrid
R1399 T2381 T2378 compound hybrid,system
R1400 T2382 T2381 punct -,hybrid
R1401 T2383 T2378 prep with,system
R1402 T2384 T2385 det a,construct
R1403 T2385 T2383 pobj construct,with
R1404 T2386 T2387 punct (,PAX6CTP
R1405 T2387 T2385 parataxis PAX6CTP,construct
R1406 T2388 T2387 punct ),PAX6CTP
R1407 T2389 T2390 prep in,fused
R1408 T2390 T2385 relcl fused,construct
R1409 T2391 T2389 pobj which,in
R1410 T2392 T2393 det the,peptide
R1411 T2393 T2390 nsubjpass peptide,fused
R1412 T2394 T2395 nummod 32,acid
R1413 T2395 T2393 nmod acid,peptide
R1414 T2396 T2395 nmod amino,acid
R1415 T2397 T2398 npadvmod C,terminal
R1416 T2398 T2393 amod terminal,peptide
R1417 T2399 T2398 punct -,terminal
R1418 T2400 T2390 auxpass was,fused
R1419 T2401 T2390 prep to,fused
R1420 T2402 T2403 det the,domain
R1421 T2403 T2401 pobj domain,to
R1422 T2404 T2403 compound yeast,domain
R1423 T2405 T2403 compound GAL4,domain
R1424 T2406 T2407 compound DNA,binding
R1425 T2407 T2403 compound binding,domain
R1426 T2408 T2369 punct .,tested
R1427 T2410 T2411 nsubj We,chose
R1428 T2412 T2413 aux to,screen
R1429 T2413 T2411 xcomp screen,chose
R1430 T2414 T2415 det a,library
R1431 T2415 T2413 dobj library,screen
R1432 T2416 T2417 compound mouse,brain
R1433 T2417 T2415 compound brain,library
R1434 T2418 T2415 compound cDNA,library
R1435 T2419 T2420 mark as,were
R1436 T2420 T2411 advcl were,chose
R1437 T2421 T2422 det no,libraries
R1438 T2422 T2420 nsubj libraries,were
R1439 T2423 T2422 amod human,libraries
R1440 T2424 T2420 acomp available,were
R1441 T2425 T2411 punct .,chose
R1442 T2427 T2428 prep Given,reasoned
R1443 T2429 T2430 det the,fact
R1444 T2430 T2427 pobj fact,Given
R1445 T2431 T2432 mark that,is
R1446 T2432 T2430 acl is,fact
R1447 T2433 T2434 det the,sequence
R1448 T2434 T2432 nsubj sequence,is
R1449 T2435 T2436 compound amino,acid
R1450 T2436 T2434 compound acid,sequence
R1451 T2437 T2434 prep of,sequence
R1452 T2438 T2439 det the,protein
R1453 T2439 T2437 pobj protein,of
R1454 T2440 T2439 compound PAX6,protein
R1455 T2441 T2432 acomp identical,is
R1456 T2442 T2432 prep in,is
R1457 T2443 T2442 pobj man,in
R1458 T2444 T2443 cc and,man
R1459 T2445 T2443 conj mouse,man
R1460 T2446 T2428 punct ", ",reasoned
R1461 T2447 T2428 nsubj we,reasoned
R1462 T2448 T2449 mark that,yield
R1463 T2449 T2428 ccomp yield,reasoned
R1464 T2450 T2451 det a,library
R1465 T2451 T2449 nsubj library,yield
R1466 T2452 T2453 compound mouse,brain
R1467 T2453 T2451 compound brain,library
R1468 T2454 T2449 aux would,yield
R1469 T2455 T2456 amod relevant,interactors
R1470 T2456 T2449 dobj interactors,yield
R1471 T2457 T2428 punct .,reasoned
R1472 T2459 T2460 prep For,carried
R1473 T2461 T2459 pobj comparison,For
R1474 T2462 T2460 nsubj we,carried
R1475 T2463 T2460 advmod also,carried
R1476 T2464 T2460 prt out,carried
R1477 T2465 T2466 det the,screen
R1478 T2466 T2460 dobj screen,carried
R1479 T2467 T2460 advcl using,carried
R1480 T2468 T2469 det a,construct
R1481 T2469 T2467 dobj construct,using
R1482 T2470 T2469 acl containing,construct
R1483 T2471 T2472 det the,domain
R1484 T2472 T2470 dobj domain,containing
R1485 T2473 T2472 amod whole,domain
R1486 T2474 T2472 compound PST,domain
R1487 T2475 T2469 punct (,construct
R1488 T2476 T2469 appos PAX6PST,construct
R1489 T2477 T2469 punct ),construct
R1490 T2478 T2460 punct .,carried
R1491 T2480 T2481 det The,screen
R1492 T2481 T2486 nsubj screen,gave
R1493 T2482 T2483 npadvmod C,terminal
R1494 T2483 T2481 amod terminal,screen
R1495 T2484 T2483 punct -,terminal
R1496 T2485 T2481 compound peptide,screen
R1497 T2487 T2488 nummod 15,colonies
R1498 T2488 T2486 dobj colonies,gave
R1499 T2489 T2490 dep that,were
R1500 T2490 T2488 relcl were,colonies
R1501 T2491 T2490 acomp positive,were
R1502 T2492 T2491 prep with,positive
R1503 T2493 T2494 det all,reporters
R1504 T2494 T2492 pobj reporters,with
R1505 T2495 T2494 nummod three,reporters
R1506 T2496 T2486 cc and,gave
R1507 T2497 T2498 det the,screen
R1508 T2498 T2501 nsubj screen,gave
R1509 T2499 T2498 compound PST,screen
R1510 T2500 T2498 compound domain,screen
R1511 T2501 T2486 conj gave,gave
R1512 T2502 T2503 nummod 62,colonies
R1513 T2503 T2501 dobj colonies,gave
R1514 T2504 T2501 punct .,gave
R1515 T2506 T2507 det The,plasmids
R1516 T2507 T2509 nsubjpass plasmids,isolated
R1517 T2508 T2507 amod interacting,plasmids
R1518 T2510 T2509 auxpass were,isolated
R1519 T2511 T2509 cc and,isolated
R1520 T2512 T2513 det the,inserts
R1521 T2513 T2515 nsubj inserts,sequenced
R1522 T2514 T2513 compound cDNA,inserts
R1523 T2515 T2509 conj sequenced,isolated
R1524 T2516 T2515 punct .,sequenced
R1525 T2518 T2519 nummod Three,cDNAs
R1526 T2519 T2520 nsubjpass cDNAs,identified
R1527 T2521 T2520 auxpass were,identified
R1528 T2522 T2523 nummod 3,times
R1529 T2523 T2520 npadvmod times,identified
R1530 T2524 T2522 cc or,3
R1531 T2525 T2522 conj more,3
R1532 T2526 T2520 punct ", ",identified
R1533 T2527 T2520 dep Homer3,identified
R1534 T2528 T2527 punct (,Homer3
R1535 T2529 T2527 appos NM_011984,Homer3
R1536 T2530 T2527 punct ),Homer3
R1537 T2531 T2527 punct ", ",Homer3
R1538 T2532 T2527 conj Dncl1,Homer3
R1539 T2533 T2532 punct (,Dncl1
R1540 T2534 T2535 nmod Dynein,chain
R1541 T2535 T2532 appos chain,Dncl1
R1542 T2536 T2535 amod cytoplasmic,chain
R1543 T2537 T2535 amod light,chain
R1544 T2538 T2535 nummod 1,chain
R1545 T2539 T2535 punct ", ",chain
R1546 T2540 T2535 appos NM_019682,chain
R1547 T2541 T2535 punct ", ",chain
R1548 T2542 T2543 advmod also,known
R1549 T2543 T2535 acl known,chain
R1550 T2544 T2543 prep as,known
R1551 T2545 T2544 pobj Pin,as
R1552 T2546 T2545 cc or,Pin
R1553 T2547 T2545 conj Dlc8,Pin
R1554 T2548 T2532 punct ),Dncl1
R1555 T2549 T2532 cc and,Dncl1
R1556 T2550 T2532 conj Trim11,Dncl1
R1557 T2551 T2550 punct (,Trim11
R1558 T2552 T2553 amod Tripartite,motif
R1559 T2553 T2554 compound motif,member
R1560 T2554 T2550 appos member,Trim11
R1561 T2555 T2554 compound protein,member
R1562 T2556 T2554 compound family,member
R1563 T2557 T2554 nummod 11,member
R1564 T2558 T2554 punct ", ",member
R1565 T2559 T2554 appos NM_053168,member
R1566 T2560 T2550 punct ),Trim11
R1567 T2561 T2520 punct .,identified
R1568 T2563 T2564 nsubjpass Homer3,identified
R1569 T2565 T2566 punct (,clones
R1570 T2566 T2563 parataxis clones,Homer3
R1571 T2567 T2566 nummod 6,clones
R1572 T2568 T2566 punct ),clones
R1573 T2569 T2563 cc and,Homer3
R1574 T2570 T2563 conj Dncl1,Homer3
R1575 T2571 T2572 punct (,clones
R1576 T2572 T2570 parataxis clones,Dncl1
R1577 T2573 T2572 nummod 2,clones
R1578 T2574 T2572 punct ),clones
R1579 T2575 T2564 auxpass were,identified
R1580 T2576 T2564 prep in,identified
R1581 T2577 T2578 det the,screen
R1582 T2578 T2576 pobj screen,in
R1583 T2579 T2580 npadvmod C,terminal
R1584 T2580 T2578 amod terminal,screen
R1585 T2581 T2580 punct -,terminal
R1586 T2582 T2578 compound peptide,screen
R1587 T2583 T2564 punct .,identified
R1588 T2585 T2586 nsubjpass Homer3,identified
R1589 T2587 T2588 punct (,clones
R1590 T2588 T2585 parataxis clones,Homer3
R1591 T2589 T2588 nummod 7,clones
R1592 T2590 T2588 punct ),clones
R1593 T2591 T2585 punct ", ",Homer3
R1594 T2592 T2585 conj Dncl1,Homer3
R1595 T2593 T2594 punct (,clones
R1596 T2594 T2592 parataxis clones,Dncl1
R1597 T2595 T2594 nummod 2,clones
R1598 T2596 T2594 punct ),clones
R1599 T2597 T2592 cc and,Dncl1
R1600 T2598 T2592 conj Trim11,Dncl1
R1601 T2599 T2600 punct (,clones
R1602 T2600 T2598 parataxis clones,Trim11
R1603 T2601 T2600 nummod 6,clones
R1604 T2602 T2600 punct ),clones
R1605 T2603 T2586 auxpass were,identified
R1606 T2604 T2586 prep in,identified
R1607 T2605 T2606 det the,screen
R1608 T2606 T2604 pobj screen,in
R1609 T2607 T2606 compound PST,screen
R1610 T2608 T2606 compound domain,screen
R1611 T2609 T2586 punct .,identified
R1612 T2611 T2612 det All,inserts
R1613 T2612 T2614 nsubj inserts,were
R1614 T2613 T2612 compound cDNA,inserts
R1615 T2615 T2614 prep in,were
R1616 T2616 T2615 punct -,in
R1617 T2617 T2615 pobj frame,in
R1618 T2618 T2617 prep with,frame
R1619 T2619 T2620 det the,region
R1620 T2620 T2618 pobj region,with
R1621 T2621 T2620 compound coding,region
R1622 T2622 T2620 prep of,region
R1623 T2623 T2624 det the,domain
R1624 T2624 T2622 pobj domain,of
R1625 T2625 T2624 compound pPC86,domain
R1626 T2626 T2624 compound GAL4,domain
R1627 T2627 T2624 compound activation,domain
R1628 T2628 T2614 punct .,were
R1629 T2630 T2631 nsubj None,was
R1630 T2632 T2630 prep of,None
R1631 T2633 T2634 det the,cDNAs
R1632 T2634 T2632 pobj cDNAs,of
R1633 T2635 T2631 acomp present,was
R1634 T2636 T2631 prep in,was
R1635 T2637 T2638 det a,list
R1636 T2638 T2636 pobj list,in
R1637 T2639 T2638 prep of,list
R1638 T2640 T2641 amod known,positives
R1639 T2641 T2639 pobj positives,of
R1640 T2642 T2641 amod false,positives
R1641 T2643 T2644 punct [,34
R1642 T2644 T2631 parataxis 34,was
R1643 T2645 T2644 punct ],34
R1644 T2646 T2631 punct .,was
R1645 T2648 T2649 nsubj HOMER3,is
R1646 T2650 T2651 det a,member
R1647 T2651 T2649 attr member,is
R1648 T2652 T2651 prep of,member
R1649 T2653 T2654 det the,family
R1650 T2654 T2652 pobj family,of
R1651 T2655 T2654 compound HOMER,family
R1652 T2656 T2654 prep of,family
R1653 T2657 T2658 amod neuronal,proteins
R1654 T2658 T2656 pobj proteins,of
R1655 T2659 T2660 amod post-synaptic,density
R1656 T2660 T2658 nmod density,proteins
R1657 T2661 T2660 punct (,density
R1658 T2662 T2660 appos PSD,density
R1659 T2663 T2658 punct ),proteins
R1660 T2664 T2665 punct [,35
R1661 T2665 T2649 parataxis 35,is
R1662 T2666 T2665 punct ],35
R1663 T2667 T2649 punct .,is
R1664 T2669 T2670 nsubj DNCL1,is
R1665 T2671 T2672 det a,subunit
R1666 T2672 T2670 attr subunit,is
R1667 T2673 T2672 prep of,subunit
R1668 T2674 T2675 nummod two,complexes
R1669 T2675 T2673 pobj complexes,of
R1670 T2676 T2675 compound motor,complexes
R1671 T2677 T2675 compound protein,complexes
R1672 T2678 T2675 punct ", ",complexes
R1673 T2679 T2675 appos dynein,complexes
R1674 T2680 T2679 cc and,dynein
R1675 T2681 T2682 compound myosin,Va
R1676 T2682 T2679 conj Va,dynein
R1677 T2683 T2682 punct -,Va
R1678 T2684 T2679 punct ", ",dynein
R1679 T2685 T2686 dep both,involved
R1680 T2686 T2679 relcl involved,dynein
R1681 T2687 T2685 prep of,both
R1682 T2688 T2687 pobj which,of
R1683 T2689 T2686 auxpass are,involved
R1684 T2690 T2686 prep in,involved
R1685 T2691 T2692 amod intracellular,trafficking
R1686 T2692 T2690 pobj trafficking,in
R1687 T2693 T2692 prep of,trafficking
R1688 T2694 T2693 pobj proteins,of
R1689 T2695 T2694 cc and,proteins
R1690 T2696 T2694 conj organelles,proteins
R1691 T2697 T2686 prep in,involved
R1692 T2698 T2697 pobj neurons,in
R1693 T2699 T2700 punct [,37
R1694 T2700 T2670 parataxis 37,is
R1695 T2701 T2700 nummod 36,37
R1696 T2702 T2700 punct ",",37
R1697 T2703 T2700 punct ],37
R1698 T2704 T2670 punct .,is
R1699 T2706 T2707 nsubj TRIM11,is
R1700 T2708 T2709 det a,member
R1701 T2709 T2707 attr member,is
R1702 T2710 T2709 prep of,member
R1703 T2711 T2712 det the,family
R1704 T2712 T2710 pobj family,of
R1705 T2713 T2714 amod tripartite,motif
R1706 T2714 T2712 compound motif,family
R1707 T2715 T2712 compound protein,family
R1708 T2716 T2707 cc and,is
R1709 T2717 T2707 conj contains,is
R1710 T2718 T2719 det a,finger
R1711 T2719 T2717 dobj finger,contains
R1712 T2720 T2719 compound RING,finger
R1713 T2721 T2719 punct ", ",finger
R1714 T2722 T2723 det a,finger
R1715 T2723 T2719 conj finger,finger
R1716 T2724 T2725 compound B,box
R1717 T2725 T2723 compound box,finger
R1718 T2726 T2725 punct -,box
R1719 T2727 T2723 compound zinc,finger
R1720 T2728 T2723 punct ", ",finger
R1721 T2729 T2730 det a,domain
R1722 T2730 T2723 conj domain,finger
R1723 T2731 T2732 amod coiled,coil
R1724 T2732 T2730 compound coil,domain
R1725 T2733 T2730 cc and,domain
R1726 T2734 T2735 det a,domain
R1727 T2735 T2730 conj domain,domain
R1728 T2736 T2735 compound B30.2,domain
R1729 T2737 T2738 punct [,38
R1730 T2738 T2717 parataxis 38,contains
R1731 T2739 T2738 punct ],38
R1732 T2740 T2707 punct .,is
R1733 T2742 T2743 det The,significance
R1734 T2743 T2745 nsubjpass significance,discussed
R1735 T2744 T2743 amod possible,significance
R1736 T2746 T2743 prep of,significance
R1737 T2747 T2748 det the,interactions
R1738 T2748 T2746 pobj interactions,of
R1739 T2749 T2748 prep between,interactions
R1740 T2750 T2751 det these,proteins
R1741 T2751 T2749 pobj proteins,between
R1742 T2752 T2751 cc and,proteins
R1743 T2753 T2751 conj PAX6,proteins
R1744 T2754 T2745 auxpass is,discussed
R1745 T2755 T2745 advmod below,discussed
R1746 T2756 T2745 punct .,discussed

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T2247 52-62 CHEBI_SO_EXT:C_terminus_or_C_terminal_region denotes C-terminal
T2248 63-70 CHEBI_SO_EXT:peptide_or_peptide_region denotes peptide
T2249 92-99 CHEBI_PR_EXT:protein denotes protein
T2250 100-107 CHEBI_PR_EXT:protein denotes protein
T2251 156-160 SO_EXT:cDNA denotes cDNA
T2252 179-184 NCBITaxon_EXT:yeast denotes yeast
T2253 210-219 SO_EXT:engineered_biological_sequence denotes construct
T2254 246-256 CHEBI_SO_EXT:amino_acid denotes amino acid
T2255 257-267 CHEBI_SO_EXT:C_terminus_or_C_terminal_region denotes C-terminal
T2256 268-275 CHEBI_SO_EXT:peptide_or_peptide_region denotes peptide
T2257 280-285 SO_EXT:sequence_fusion_process denotes fused
T2258 293-298 NCBITaxon_EXT:yeast denotes yeast
T2259 299-303 PR_EXT:P04386 denotes GAL4
T2260 304-307 CHEBI_SO_EXT:DNA denotes DNA
T2261 308-315 CHEMINF_GO_EXT:chemical_binding_or_bond_formation denotes binding
T2262 316-322 SO_EXT:0000417 denotes domain
T2263 345-350 NCBITaxon:10088 denotes mouse
T2264 351-356 UBERON:0000955 denotes brain
T2265 357-361 SO_EXT:cDNA denotes cDNA
T2266 376-381 NCBITaxon:9606 denotes human
T2267 432-442 CHEBI_SO_EXT:amino_acid denotes amino acid
T2268 443-451 SO_EXT:biological_sequence denotes sequence
T2269 459-463 PR_EXT:000012318 denotes PAX6
T2270 464-471 CHEBI_PR_EXT:protein denotes protein
T2271 488-491 NCBITaxon:9606 denotes man
T2272 496-501 NCBITaxon:10088 denotes mouse
T2273 522-527 NCBITaxon:10088 denotes mouse
T2274 528-533 UBERON:0000955 denotes brain
T2275 630-639 SO_EXT:engineered_biological_sequence denotes construct
T2276 665-671 SO_EXT:0000417 denotes domain
T2277 687-697 CHEBI_SO_EXT:C_terminus_or_C_terminal_region denotes C-terminal
T2278 698-705 CHEBI_SO_EXT:peptide_or_peptide_region denotes peptide
T2279 786-792 SO_EXT:0000417 denotes domain
T2280 834-842 SO_EXT:0000155 denotes plasmids
T2281 865-869 SO_EXT:cDNA denotes cDNA
T2282 870-877 SO_EXT:0000667 denotes inserts
T2283 895-900 SO_EXT:cDNA denotes cDNAs
T2284 934-940 PR_EXT:000008680 denotes Homer3
T2285 954-959 PR_EXT:000002325 denotes Dncl1
T2286 961-967 GO:0030286 denotes Dynein
T2287 961-993 PR_EXT:000002325 denotes Dynein cytoplasmic light chain 1
T2288 968-979 GO:0005737 denotes cytoplasmic
T2289 1020-1023 PR_EXT:000002325 denotes Pin
T2290 1027-1031 PR_EXT:000002325 denotes Dlc8
T2291 1037-1043 PR_EXT:000016642 denotes Trim11
T2292 1045-1086 PR_EXT:000016642 denotes Tripartite motif protein family member 11
T2293 1056-1061 SO_EXT:sequence_or_structure_motif denotes motif
T2294 1062-1069 CHEBI_PR_EXT:protein denotes protein
T2295 1100-1106 PR_EXT:000008680 denotes Homer3
T2296 1110-1116 SO_EXT:sequence_cloned_entity denotes clones
T2297 1122-1127 PR_EXT:000002325 denotes Dncl1
T2298 1131-1137 SO_EXT:sequence_cloned_entity denotes clones
T2299 1162-1172 CHEBI_SO_EXT:C_terminus_or_C_terminal_region denotes C-terminal
T2300 1173-1180 CHEBI_SO_EXT:peptide_or_peptide_region denotes peptide
T2301 1189-1195 PR_EXT:000008680 denotes Homer3
T2302 1199-1205 SO_EXT:sequence_cloned_entity denotes clones
T2303 1208-1213 PR_EXT:000002325 denotes Dncl1
T2304 1217-1223 SO_EXT:sequence_cloned_entity denotes clones
T2305 1229-1235 PR_EXT:000016642 denotes Trim11
T2306 1239-1245 SO_EXT:sequence_cloned_entity denotes clones
T2307 1274-1280 SO_EXT:0000417 denotes domain
T2308 1293-1297 SO_EXT:cDNA denotes cDNA
T2309 1298-1305 SO_EXT:0000667 denotes inserts
T2310 1311-1319 SO:0001817 denotes in-frame
T2311 1329-1342 SO_EXT:coding_sequence denotes coding region
T2312 1356-1360 PR_EXT:P04386 denotes GAL4
T2313 1372-1378 SO_EXT:0000417 denotes domain
T2314 1392-1397 SO_EXT:cDNA denotes cDNAs
T2315 1451-1457 PR_EXT:000008680 denotes HOMER3
T2316 1477-1482 PR_EXT:HOMER denotes HOMER
T2317 1493-1501 CL:0000540 denotes neuronal
T2318 1502-1523 GO:0014069 denotes post-synaptic density
T2319 1525-1528 GO:0014069 denotes PSD
T2320 1530-1538 CHEBI_PR_EXT:protein denotes proteins
T2321 1545-1550 PR_EXT:000002325 denotes DNCL1
T2322 1571-1576 GO_EXT:biological_movement_or_translocation_process denotes motor
T2323 1577-1584 CHEBI_PR_EXT:protein denotes protein
T2324 1577-1594 GO:0043234 denotes protein complexes
T2325 1596-1602 GO:0030286 denotes dynein
T2326 1607-1616 PR_EXT:000010865 denotes myosin-Va
T2327 1648-1661 GO:0005622 denotes intracellular
T2328 1648-1685 GO:0006886 denotes intracellular trafficking of proteins
T2329 1653-1661 CL_GO_EXT:cell denotes cellular
T2330 1662-1676 _FRAGMENT denotes trafficking of
T2331 1690-1700 GO:0051656 denotes organelles
T2332 1677-1685 CHEBI_PR_EXT:protein denotes proteins
T2333 1690-1700 GO:0043226 denotes organelles
T2334 1704-1711 CL:0000540 denotes neurons
T2335 1721-1727 PR_EXT:000016642 denotes TRIM11
T2336 1758-1763 SO_EXT:sequence_or_structure_motif denotes motif
T2337 1764-1771 CHEBI_PR_EXT:protein denotes protein
T2338 1815-1819 CHEBI_EXT:zinc denotes zinc
T2339 1830-1841 SO_EXT:0001080 denotes coiled coil
T2340 1842-1848 SO_EXT:0000417 denotes domain
T2341 1861-1867 SO_EXT:0000417 denotes domain
T2342 1934-1942 CHEBI_PR_EXT:protein denotes proteins
T2343 1947-1951 PR_EXT:000012318 denotes PAX6
T2246 0-5 NCBITaxon_EXT:yeast denotes Yeast
R1364 T2331 T2330 _lexicallyChainedTo organelles,trafficking of

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T2194 299-303 PR:P04386 denotes GAL4
T2195 316-322 SO:0000417 denotes domain
T2196 345-350 NCBITaxon:10088 denotes mouse
T2197 351-356 UBERON:0000955 denotes brain
T2198 376-381 NCBITaxon:9606 denotes human
T2199 459-463 PR:000012318 denotes PAX6
T2200 488-491 NCBITaxon:9606 denotes man
T2201 496-501 NCBITaxon:10088 denotes mouse
T2202 522-527 NCBITaxon:10088 denotes mouse
T2203 528-533 UBERON:0000955 denotes brain
T2204 665-671 SO:0000417 denotes domain
T2205 786-792 SO:0000417 denotes domain
T2206 834-842 SO:0000155 denotes plasmids
T2207 870-877 SO:0000667 denotes inserts
T2208 934-940 PR:000008680 denotes Homer3
T2209 954-959 PR:000002325 denotes Dncl1
T2210 961-967 GO:0030286 denotes Dynein
T2211 961-993 PR:000002325 denotes Dynein cytoplasmic light chain 1
T2212 968-979 GO:0005737 denotes cytoplasmic
T2213 1020-1023 PR:000002325 denotes Pin
T2214 1027-1031 PR:000002325 denotes Dlc8
T2215 1037-1043 PR:000016642 denotes Trim11
T2216 1045-1086 PR:000016642 denotes Tripartite motif protein family member 11
T2217 1100-1106 PR:000008680 denotes Homer3
T2218 1122-1127 PR:000002325 denotes Dncl1
T2219 1189-1195 PR:000008680 denotes Homer3
T2220 1208-1213 PR:000002325 denotes Dncl1
T2221 1229-1235 PR:000016642 denotes Trim11
T2222 1274-1280 SO:0000417 denotes domain
T2223 1298-1305 SO:0000667 denotes inserts
T2224 1311-1319 SO:0001817 denotes in-frame
T2225 1356-1360 PR:P04386 denotes GAL4
T2226 1372-1378 SO:0000417 denotes domain
T2227 1451-1457 PR:000008680 denotes HOMER3
T2228 1493-1501 CL:0000540 denotes neuronal
T2229 1502-1523 GO:0014069 denotes post-synaptic density
T2230 1525-1528 GO:0014069 denotes PSD
T2231 1545-1550 PR:000002325 denotes DNCL1
T2232 1577-1594 GO:0043234 denotes protein complexes
T2233 1596-1602 GO:0030286 denotes dynein
T2234 1607-1616 PR:000010865 denotes myosin-Va
T2235 1648-1661 GO:0005622 denotes intracellular
T2236 1648-1685 GO:0006886 denotes intracellular trafficking of proteins
T2237 1662-1676 _FRAGMENT denotes trafficking of
T2238 1690-1700 GO:0051656 denotes organelles
T2239 1690-1700 GO:0043226 denotes organelles
T2240 1704-1711 CL:0000540 denotes neurons
T2241 1721-1727 PR:000016642 denotes TRIM11
T2242 1830-1841 SO:0001080 denotes coiled coil
T2243 1842-1848 SO:0000417 denotes domain
T2244 1861-1867 SO:0000417 denotes domain
T2245 1947-1951 PR:000012318 denotes PAX6
R1363 T2238 T2237 _lexicallyChainedTo organelles,trafficking of