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PMC:1208879 / 511-1127 JSONTXT

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craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T82 270-274 PR:000012318 denotes PAX6
T83 305-311 SO:0000417 denotes domain
T84 325-329 PR:000012318 denotes PAX6
T85 372-393 GO:0014069 denotes post-synaptic density
T86 395-398 GO:0014069 denotes PSD
T87 408-414 PR:000008680 denotes HOMER3
T88 420-426 GO:0030286 denotes dynein
T89 435-440 PR:000002325 denotes DNCL1
T90 475-481 PR:000016642 denotes TRIM11
T91 500-504 PR:000012318 denotes PAX6
T92 555-558 UBERON:0000970 denotes eye
T79 102-106 PR:000012318 denotes PAX6
T80 183-188 UBERON:0000955 denotes brain
T81 189-198 GO:0010467 denotes expressed

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T130 59-68 SO_EXT:biological_conservation_process_or_quality denotes conserved
T131 69-76 CHEBI_SO_EXT:peptide_or_peptide_region denotes peptide
T132 84-94 CHEBI_SO_EXT:C_terminus_or_C_terminal_region denotes C-terminus
T133 102-106 PR_EXT:000012318 denotes PAX6
T134 107-114 CHEBI_PR_EXT:protein denotes protein
T135 116-121 NCBITaxon_EXT:yeast denotes Yeast
T136 183-188 UBERON:0000955 denotes brain
T137 189-198 GO:0010467 denotes expressed
T138 199-207 CHEBI_PR_EXT:protein denotes proteins
T139 231-241 CHEBI_SO_EXT:C_terminus_or_C_terminal_region denotes C-terminal
T140 242-249 CHEBI_SO_EXT:peptide_or_peptide_region denotes peptide
T141 270-274 PR_EXT:000012318 denotes PAX6
T142 275-282 CHEBI_SO_EXT:proline denotes proline
T143 283-289 CHEBI_SO_EXT:serine denotes serine
T144 290-299 CHEBI_SO_EXT:threonine denotes threonine
T145 305-311 SO_EXT:0000417 denotes domain
T146 325-329 PR_EXT:000012318 denotes PAX6
T147 342-350 CHEBI_PR_EXT:protein denotes proteins
T148 372-393 GO:0014069 denotes post-synaptic density
T149 395-398 GO:0014069 denotes PSD
T150 400-407 CHEBI_PR_EXT:protein denotes protein
T151 408-414 PR_EXT:000008680 denotes HOMER3
T152 420-426 GO:0030286 denotes dynein
T153 435-440 PR_EXT:000002325 denotes DNCL1
T154 461-466 SO_EXT:sequence_or_structure_motif denotes motif
T155 467-474 CHEBI_PR_EXT:protein denotes protein
T156 475-481 PR_EXT:000016642 denotes TRIM11
T157 489-499 CHEBI_SO_EXT:C_terminus_or_C_terminal_region denotes C-terminal
T158 500-504 PR_EXT:000012318 denotes PAX6
T159 505-514 SO_EXT:sequence_alteration_entity_or_process denotes mutations
T160 555-558 UBERON:0000970 denotes eye

craft-sa-dev

Id Subject Object Predicate Lexical cue
T270 0-2 PRP denotes We
T271 3-7 VBD denotes used
T272 8-22 NN denotes bioinformatics
T273 23-33 NNS denotes techniques
T274 34-36 TO denotes to
T275 37-49 VB denotes characterise
T276 50-51 DT denotes a
T277 69-76 NN denotes peptide
T278 52-58 RB denotes highly
T279 59-68 VBN denotes conserved
T280 77-79 IN denotes at
T281 80-83 DT denotes the
T282 86-94 NN denotes terminus
T283 84-85 NN denotes C
T284 85-86 HYPH denotes -
T285 95-97 IN denotes of
T286 98-101 DT denotes the
T287 107-114 NN denotes protein
T288 102-106 NN denotes PAX6
T289 114-115 . denotes .
T290 115-312 sentence denotes Yeast two-hybrid library screens were then carried out to identify brain-expressed proteins that interact with the C-terminal peptide and with the entire PAX6 proline-serine-threonine-rich domain.
T291 116-121 NN denotes Yeast
T292 141-148 NNS denotes screens
T293 122-125 CD denotes two
T294 126-132 NN denotes hybrid
T295 125-126 HYPH denotes -
T296 133-140 NN denotes library
T297 159-166 VBN denotes carried
T298 149-153 VBD denotes were
T299 154-158 RB denotes then
T300 167-170 RP denotes out
T301 171-173 TO denotes to
T302 174-182 VB denotes identify
T303 183-188 NN denotes brain
T304 189-198 VBN denotes expressed
T305 188-189 HYPH denotes -
T306 199-207 NN denotes proteins
T307 208-212 WDT denotes that
T308 213-221 VBP denotes interact
T309 222-226 IN denotes with
T310 227-230 DT denotes the
T311 242-249 NN denotes peptide
T312 231-232 NN denotes C
T313 233-241 JJ denotes terminal
T314 232-233 HYPH denotes -
T315 250-253 CC denotes and
T316 254-258 IN denotes with
T317 259-262 DT denotes the
T318 305-311 NN denotes domain
T319 263-269 JJ denotes entire
T320 270-274 NN denotes PAX6
T321 275-282 NN denotes proline
T322 290-299 NN denotes threonine
T323 282-283 HYPH denotes -
T324 283-289 NN denotes serine
T325 289-290 HYPH denotes -
T326 300-304 JJ denotes rich
T327 299-300 HYPH denotes -
T328 311-312 . denotes .
T329 312-482 sentence denotes Three novel PAX6-interacting proteins were identified: the post-synaptic density (PSD) protein HOMER3, the dynein subunit DNCL1, and the tripartite motif protein TRIM11.
T330 313-318 CD denotes Three
T331 342-350 NN denotes proteins
T332 319-324 JJ denotes novel
T333 325-329 NN denotes PAX6
T334 330-341 VBG denotes interacting
T335 329-330 HYPH denotes -
T336 356-366 VBN denotes identified
T337 351-355 VBD denotes were
T338 366-368 : denotes :
T339 368-371 DT denotes the
T340 400-407 NN denotes protein
T341 372-385 JJ denotes post-synaptic
T342 386-393 NN denotes density
T343 394-395 -LRB- denotes (
T344 395-398 NN denotes PSD
T345 398-399 -RRB- denotes )
T346 408-414 NN denotes HOMER3
T347 414-416 , denotes ,
T348 416-419 DT denotes the
T349 427-434 NN denotes subunit
T350 420-426 NN denotes dynein
T351 435-440 NN denotes DNCL1
T352 440-442 , denotes ,
T353 442-445 CC denotes and
T354 446-449 DT denotes the
T355 467-474 NN denotes protein
T356 450-460 JJ denotes tripartite
T357 461-466 NN denotes motif
T358 475-481 NN denotes TRIM11
T359 481-482 . denotes .
T360 482-616 sentence denotes Three C-terminal PAX6 mutations, previously identified in patients with eye malformations, all reduced or abolished the interactions.
T361 483-488 CD denotes Three
T362 505-514 NNS denotes mutations
T363 489-490 NN denotes C
T364 491-499 JJ denotes terminal
T365 490-491 HYPH denotes -
T366 500-504 NN denotes PAX6
T367 578-585 VBD denotes reduced
T368 514-516 , denotes ,
T369 516-526 RB denotes previously
T370 527-537 VBN denotes identified
T371 538-540 IN denotes in
T372 541-549 NNS denotes patients
T373 550-554 IN denotes with
T374 555-558 NN denotes eye
T375 559-572 NNS denotes malformations
T376 572-574 , denotes ,
T377 574-577 DT denotes all
T378 586-588 CC denotes or
T379 589-598 VBD denotes abolished
T380 599-602 DT denotes the
T381 603-615 NNS denotes interactions
T382 615-616 . denotes .
R88 T277 T275 dobj peptide,characterise
R89 T278 T279 advmod highly,conserved
R90 T279 T277 amod conserved,peptide
R93 T282 T280 pobj terminus,at
R94 T283 T282 compound C,terminus
R95 T284 T282 punct -,terminus
R98 T287 T285 pobj protein,of
R99 T288 T287 compound PAX6,protein
R102 T292 T297 nsubjpass screens,carried
R103 T293 T294 nummod two,hybrid
R105 T295 T294 punct -,hybrid
R106 T296 T292 compound library,screens
R113 T304 T306 amod expressed,proteins
R114 T305 T304 punct -,expressed
R120 T311 T309 pobj peptide,with
R121 T312 T313 npadvmod C,terminal
R123 T314 T313 punct -,terminal
R127 T318 T316 pobj domain,with
R128 T319 T318 amod entire,domain
R129 T320 T318 nmod PAX6,domain
R130 T321 T322 compound proline,threonine
R131 T322 T326 npadvmod threonine,rich
R132 T323 T322 punct -,threonine
R133 T324 T322 compound serine,threonine
R134 T325 T322 punct -,threonine
R136 T327 T326 punct -,rich
R139 T331 T336 nsubjpass proteins,identified
R140 T332 T331 amod novel,proteins
R141 T333 T334 npadvmod PAX6,interacting
R143 T335 T334 punct -,interacting
R147 T340 T336 dep protein,identified
R148 T341 T342 amod post-synaptic,density
R149 T342 T340 nmod density,protein
R150 T343 T342 punct (,density
R151 T344 T342 appos PSD,density
R152 T345 T340 punct ),protein
R156 T349 T340 conj subunit,protein
R157 T350 T349 compound dynein,subunit
R162 T355 T349 conj protein,subunit
R163 T356 T355 amod tripartite,protein
R164 T357 T355 compound motif,protein
R168 T362 T367 nsubj mutations,reduced
R169 T363 T364 npadvmod C,terminal
R171 T365 T364 punct -,terminal
R172 T366 T362 compound PAX6,mutations
R82 T270 T271 nsubj We,used
R83 T272 T273 compound bioinformatics,techniques
R84 T273 T271 dobj techniques,used
R85 T274 T275 aux to,characterise
R86 T275 T271 advcl characterise,used
R87 T276 T277 det a,peptide
R91 T280 T275 prep at,characterise
R92 T281 T282 det the,terminus
R96 T285 T282 prep of,terminus
R97 T286 T287 det the,protein
R100 T289 T271 punct .,used
R101 T291 T292 nmod Yeast,screens
R104 T294 T292 compound hybrid,screens
R107 T298 T297 auxpass were,carried
R108 T299 T297 advmod then,carried
R109 T300 T297 prt out,carried
R110 T301 T302 aux to,identify
R111 T302 T297 advcl identify,carried
R112 T303 T304 npadvmod brain,expressed
R115 T306 T302 dobj proteins,identify
R116 T307 T308 dep that,interact
R117 T308 T306 relcl interact,proteins
R118 T309 T308 prep with,interact
R119 T310 T311 det the,peptide
R122 T313 T311 amod terminal,peptide
R124 T315 T309 cc and,with
R125 T316 T309 conj with,with
R126 T317 T318 det the,domain
R135 T326 T318 amod rich,domain
R137 T328 T297 punct .,carried
R138 T330 T331 nummod Three,proteins
R142 T334 T331 amod interacting,proteins
R144 T337 T336 auxpass were,identified
R145 T338 T336 punct : ,identified
R146 T339 T340 det the,protein
R153 T346 T340 appos HOMER3,protein
R154 T347 T340 punct ", ",protein
R155 T348 T349 det the,subunit
R158 T351 T349 appos DNCL1,subunit
R159 T352 T349 punct ", ",subunit
R160 T353 T349 cc and,subunit
R161 T354 T355 det the,protein
R165 T358 T355 appos TRIM11,protein
R166 T359 T336 punct .,identified
R167 T361 T362 nummod Three,mutations
R170 T364 T362 amod terminal,mutations
R173 T368 T362 punct ", ",mutations
R174 T369 T370 advmod previously,identified
R175 T370 T362 acl identified,mutations
R176 T371 T370 prep in,identified
R177 T372 T371 pobj patients,in
R178 T373 T372 prep with,patients
R179 T374 T375 compound eye,malformations
R180 T375 T373 pobj malformations,with
R181 T376 T362 punct ", ",mutations
R182 T377 T362 appos all,mutations
R183 T378 T367 cc or,reduced
R184 T379 T367 conj abolished,reduced
R185 T380 T381 det the,interactions
R186 T381 T379 dobj interactions,abolished
R187 T382 T367 punct .,reduced