Id |
Subject |
Object |
Predicate |
Lexical cue |
T7486 |
598-748 |
sentence |
denotes |
Weak URA3 activation suppresses growth on plates containing 5-fluro-orotic acid while strong URA3 activation permits growth on plates lacking uracil. |
T7485 |
597-598 |
. |
denotes |
. |
T7484 |
588-597 |
NN |
denotes |
histidine |
T7483 |
580-587 |
VBG |
denotes |
lacking |
T7482 |
573-579 |
NNS |
denotes |
plates |
T7481 |
570-572 |
IN |
denotes |
on |
T7480 |
563-569 |
NN |
denotes |
growth |
T7479 |
556-562 |
VBZ |
denotes |
allows |
T7478 |
545-555 |
NN |
denotes |
activation |
T7477 |
540-544 |
NN |
denotes |
HIS3 |
T7476 |
539-598 |
sentence |
denotes |
HIS3 activation allows growth on plates lacking histidine. |
T7475 |
538-539 |
. |
denotes |
. |
T7474 |
530-538 |
NN |
denotes |
function |
T7473 |
525-529 |
NN |
denotes |
GAL4 |
T7472 |
510-524 |
VBG |
denotes |
reconstituting |
T7471 |
505-509 |
RB |
denotes |
thus |
T7470 |
503-505 |
, |
denotes |
, |
T7469 |
502-503 |
-RRB- |
denotes |
) |
T7468 |
497-502 |
NN |
denotes |
pPC86 |
T7467 |
496-497 |
-LRB- |
denotes |
( |
T7466 |
478-488 |
NN |
denotes |
activation |
T7465 |
473-477 |
NN |
denotes |
GAL4 |
T7464 |
489-495 |
NN |
denotes |
domain |
T7463 |
469-472 |
DT |
denotes |
the |
T7462 |
466-468 |
IN |
denotes |
to |
T7461 |
460-465 |
VBN |
denotes |
fused |
T7460 |
447-451 |
NN |
denotes |
prey |
T7459 |
452-459 |
NN |
denotes |
protein |
T7458 |
443-446 |
DT |
denotes |
the |
T7457 |
438-442 |
IN |
denotes |
with |
T7456 |
426-427 |
-RRB- |
denotes |
) |
T7455 |
420-426 |
NN |
denotes |
pDBLeu |
T7454 |
419-420 |
-LRB- |
denotes |
( |
T7453 |
404-411 |
NN |
denotes |
binding |
T7452 |
400-403 |
NN |
denotes |
DNA |
T7451 |
395-399 |
NN |
denotes |
GAL4 |
T7450 |
412-418 |
NN |
denotes |
domain |
T7449 |
391-394 |
DT |
denotes |
the |
T7448 |
388-390 |
IN |
denotes |
to |
T7447 |
382-387 |
VBN |
denotes |
fused |
T7446 |
369-373 |
NN |
denotes |
bait |
T7445 |
374-381 |
NN |
denotes |
protein |
T7444 |
365-368 |
DT |
denotes |
the |
T7443 |
428-437 |
VBZ |
denotes |
interacts |
T7442 |
360-364 |
WRB |
denotes |
when |
T7441 |
346-349 |
VBP |
denotes |
are |
T7440 |
350-359 |
VBN |
denotes |
activated |
T7439 |
336-345 |
NNS |
denotes |
Reporters |
T7438 |
335-539 |
sentence |
denotes |
Reporters are activated when the bait protein fused to the GAL4 DNA binding domain (pDBLeu) interacts with the prey protein fused to the GAL4 activation domain (pPC86), thus reconstituting GAL4 function. |
T7437 |
334-335 |
. |
denotes |
. |
T7436 |
322-334 |
NNS |
denotes |
interactions |
T7435 |
313-321 |
JJ |
denotes |
positive |
T7434 |
304-312 |
VB |
denotes |
identify |
T7433 |
301-303 |
TO |
denotes |
to |
T7432 |
299-301 |
, |
denotes |
, |
T7431 |
295-299 |
NN |
denotes |
lacZ |
T7430 |
291-294 |
CC |
denotes |
and |
T7429 |
286-290 |
NN |
denotes |
URA3 |
T7428 |
284-286 |
, |
denotes |
, |
T7427 |
280-284 |
NN |
denotes |
HIS3 |
T7426 |
278-280 |
, |
denotes |
, |
T7425 |
264-272 |
NN |
denotes |
reporter |
T7424 |
253-254 |
HYPH |
denotes |
- |
T7423 |
254-263 |
VBN |
denotes |
activated |
T7422 |
249-253 |
NN |
denotes |
GAL4 |
T7421 |
273-278 |
NNS |
denotes |
genes |
T7420 |
243-248 |
CD |
denotes |
three |
T7419 |
238-242 |
VBZ |
denotes |
uses |
T7418 |
231-237 |
NN |
denotes |
system |
T7417 |
227-230 |
DT |
denotes |
The |
T7416 |
226-335 |
sentence |
denotes |
The system uses three GAL4-activated reporter genes, HIS3, URA3 and lacZ, to identify positive interactions. |
T7415 |
225-226 |
. |
denotes |
. |
T7414 |
208-218 |
NN |
denotes |
activation |
T7413 |
203-207 |
NN |
denotes |
GAL4 |
T7412 |
197-202 |
NN |
denotes |
yeast |
T7411 |
219-225 |
NN |
denotes |
domain |
T7410 |
193-196 |
DT |
denotes |
the |
T7409 |
190-192 |
IN |
denotes |
to |
T7408 |
184-189 |
VBN |
denotes |
fused |
T7407 |
175-183 |
NN |
denotes |
proteins |
T7406 |
166-174 |
VBZ |
denotes |
produces |
T7405 |
160-165 |
WDT |
denotes |
which |
T7404 |
158-160 |
, |
denotes |
, |
T7403 |
146-151 |
NN |
denotes |
pPC86 |
T7402 |
152-158 |
NN |
denotes |
vector |
T7401 |
142-145 |
DT |
denotes |
the |
T7400 |
139-141 |
IN |
denotes |
in |
T7399 |
123-126 |
VBD |
denotes |
was |
T7398 |
127-138 |
VBN |
denotes |
constructed |
T7397 |
115-122 |
NN |
denotes |
library |
T7396 |
111-114 |
DT |
denotes |
The |
T7395 |
110-226 |
sentence |
denotes |
The library was constructed in the pPC86 vector, which produces proteins fused to the yeast GAL4 activation domain. |
T7394 |
109-110 |
. |
denotes |
. |
T7393 |
92-98 |
NN |
denotes |
pDBLeu |
T7392 |
84-91 |
NN |
denotes |
PAX6CTP |
T7391 |
80-83 |
CC |
denotes |
and |
T7390 |
72-79 |
NN |
denotes |
PAX6PST |
T7389 |
99-109 |
NNS |
denotes |
constructs |
T7388 |
68-71 |
DT |
denotes |
the |
T7387 |
63-67 |
IN |
denotes |
with |
T7386 |
50-53 |
VBD |
denotes |
was |
T7385 |
48-49 |
-RRB- |
denotes |
) |
T7384 |
38-48 |
NNP |
denotes |
Invitrogen |
T7383 |
36-38 |
, |
denotes |
, |
T7382 |
28-36 |
NNP |
denotes |
ProQuest |
T7381 |
27-28 |
-LRB- |
denotes |
( |
T7380 |
54-62 |
VBN |
denotes |
screened |
T7379 |
14-18 |
NN |
denotes |
cDNA |
T7378 |
8-13 |
NN |
denotes |
brain |
T7377 |
2-7 |
NN |
denotes |
mouse |
T7376 |
19-26 |
NN |
denotes |
library |
T7375 |
0-1 |
DT |
denotes |
A |
T7561 |
972-973 |
. |
denotes |
. |
T7560 |
971-972 |
-RRB- |
denotes |
) |
T7559 |
970-971 |
NN |
denotes |
E |
T7558 |
969-970 |
-LRB- |
denotes |
( |
T7557 |
958-968 |
NN |
denotes |
interactor |
T7556 |
951-957 |
JJ |
denotes |
strong |
T7555 |
948-950 |
IN |
denotes |
to |
T7554 |
946-947 |
-RRB- |
denotes |
) |
T7553 |
945-946 |
NN |
denotes |
A |
T7552 |
944-945 |
-LRB- |
denotes |
( |
T7551 |
929-943 |
NN |
denotes |
non-interactor |
T7550 |
924-928 |
IN |
denotes |
from |
T7549 |
918-923 |
VBP |
denotes |
range |
T7548 |
912-917 |
WDT |
denotes |
which |
T7547 |
910-912 |
, |
denotes |
, |
T7546 |
909-910 |
NN |
denotes |
E |
T7545 |
908-909 |
SYM |
denotes |
- |
T7544 |
907-908 |
NN |
denotes |
A |
T7543 |
893-898 |
NN |
denotes |
yeast |
T7542 |
885-892 |
NN |
denotes |
control |
T7541 |
876-884 |
NNP |
denotes |
ProQuest |
T7540 |
871-875 |
CD |
denotes |
five |
T7539 |
899-906 |
NNS |
denotes |
strains |
T7538 |
867-870 |
DT |
denotes |
the |
T7537 |
862-866 |
IN |
denotes |
with |
T7536 |
853-861 |
NN |
denotes |
parallel |
T7535 |
850-852 |
IN |
denotes |
in |
T7534 |
846-849 |
RP |
denotes |
out |
T7533 |
833-837 |
VBD |
denotes |
were |
T7532 |
838-845 |
VBN |
denotes |
carried |
T7531 |
826-832 |
NNS |
denotes |
assays |
T7530 |
822-825 |
DT |
denotes |
All |
T7529 |
821-973 |
sentence |
denotes |
All assays were carried out in parallel with the five ProQuest control yeast strains A-E, which range from non-interactor (A) to strong interactor (E). |
T7528 |
820-821 |
. |
denotes |
. |
T7527 |
800-801 |
HYPH |
denotes |
- |
T7526 |
801-814 |
NN |
denotes |
galactosidase |
T7525 |
796-800 |
NN |
denotes |
beta |
T7524 |
815-820 |
NN |
denotes |
assay |
T7523 |
794-795 |
DT |
denotes |
a |
T7522 |
791-793 |
IN |
denotes |
in |
T7521 |
786-790 |
JJ |
denotes |
blue |
T7520 |
778-780 |
TO |
denotes |
to |
T7519 |
781-785 |
VB |
denotes |
turn |
T7518 |
773-774 |
HYPH |
denotes |
- |
T7517 |
774-777 |
NN |
denotes |
gal |
T7516 |
772-773 |
NN |
denotes |
X |
T7515 |
765-771 |
VBZ |
denotes |
causes |
T7514 |
754-764 |
NN |
denotes |
activation |
T7513 |
749-753 |
NN |
denotes |
LacZ |
T7512 |
748-821 |
sentence |
denotes |
LacZ activation causes X-gal to turn blue in a beta-galactosidase assay. |
T7511 |
747-748 |
. |
denotes |
. |
T7510 |
741-747 |
NN |
denotes |
uracil |
T7509 |
733-740 |
VBG |
denotes |
lacking |
T7508 |
726-732 |
NNS |
denotes |
plates |
T7507 |
723-725 |
IN |
denotes |
on |
T7506 |
716-722 |
NN |
denotes |
growth |
T7505 |
692-696 |
NN |
denotes |
URA3 |
T7504 |
697-707 |
NN |
denotes |
activation |
T7503 |
685-691 |
JJ |
denotes |
strong |
T7502 |
708-715 |
VBZ |
denotes |
permits |
T7501 |
679-684 |
IN |
denotes |
while |
T7500 |
674-678 |
NN |
denotes |
acid |
T7499 |
666-667 |
HYPH |
denotes |
- |
T7498 |
661-666 |
JJ |
denotes |
fluro |
T7497 |
660-661 |
HYPH |
denotes |
- |
T7496 |
667-673 |
JJ |
denotes |
orotic |
T7495 |
659-660 |
CD |
denotes |
5 |
T7494 |
648-658 |
VBG |
denotes |
containing |
T7493 |
641-647 |
NNS |
denotes |
plates |
T7492 |
638-640 |
IN |
denotes |
on |
T7491 |
631-637 |
NN |
denotes |
growth |
T7490 |
620-630 |
VBZ |
denotes |
suppresses |
T7489 |
604-608 |
NN |
denotes |
URA3 |
T7488 |
609-619 |
NN |
denotes |
activation |
T7487 |
599-603 |
JJ |
denotes |
Weak |
R4620 |
T7375 |
T7376 |
det |
A,library |
R4621 |
T7376 |
T7380 |
nsubjpass |
library,screened |
R4622 |
T7377 |
T7378 |
compound |
mouse,brain |
R4623 |
T7378 |
T7376 |
compound |
brain,library |
R4624 |
T7379 |
T7376 |
compound |
cDNA,library |
R4625 |
T7381 |
T7382 |
punct |
(,ProQuest |
R4626 |
T7382 |
T7376 |
parataxis |
ProQuest,library |
R4627 |
T7383 |
T7382 |
punct |
", ",ProQuest |
R4628 |
T7384 |
T7382 |
npadvmod |
Invitrogen,ProQuest |
R4629 |
T7385 |
T7382 |
punct |
),ProQuest |
R4630 |
T7386 |
T7380 |
auxpass |
was,screened |
R4631 |
T7387 |
T7380 |
prep |
with,screened |
R4632 |
T7388 |
T7389 |
det |
the,constructs |
R4633 |
T7389 |
T7387 |
pobj |
constructs,with |
R4634 |
T7390 |
T7389 |
nmod |
PAX6PST,constructs |
R4635 |
T7391 |
T7390 |
cc |
and,PAX6PST |
R4636 |
T7392 |
T7390 |
conj |
PAX6CTP,PAX6PST |
R4637 |
T7393 |
T7389 |
compound |
pDBLeu,constructs |
R4638 |
T7394 |
T7380 |
punct |
.,screened |
R4639 |
T7396 |
T7397 |
det |
The,library |
R4640 |
T7397 |
T7398 |
nsubjpass |
library,constructed |
R4641 |
T7399 |
T7398 |
auxpass |
was,constructed |
R4642 |
T7400 |
T7398 |
prep |
in,constructed |
R4643 |
T7401 |
T7402 |
det |
the,vector |
R4644 |
T7402 |
T7400 |
pobj |
vector,in |
R4645 |
T7403 |
T7402 |
compound |
pPC86,vector |
R4646 |
T7404 |
T7402 |
punct |
", ",vector |
R4647 |
T7405 |
T7406 |
dep |
which,produces |
R4648 |
T7406 |
T7402 |
relcl |
produces,vector |
R4649 |
T7407 |
T7406 |
dobj |
proteins,produces |
R4650 |
T7408 |
T7407 |
acl |
fused,proteins |
R4651 |
T7409 |
T7408 |
prep |
to,fused |
R4652 |
T7410 |
T7411 |
det |
the,domain |
R4653 |
T7411 |
T7409 |
pobj |
domain,to |
R4654 |
T7412 |
T7411 |
compound |
yeast,domain |
R4655 |
T7413 |
T7411 |
compound |
GAL4,domain |
R4656 |
T7414 |
T7411 |
compound |
activation,domain |
R4657 |
T7415 |
T7398 |
punct |
.,constructed |
R4658 |
T7417 |
T7418 |
det |
The,system |
R4659 |
T7418 |
T7419 |
nsubj |
system,uses |
R4660 |
T7420 |
T7421 |
nummod |
three,genes |
R4661 |
T7421 |
T7419 |
dobj |
genes,uses |
R4662 |
T7422 |
T7423 |
npadvmod |
GAL4,activated |
R4663 |
T7423 |
T7421 |
amod |
activated,genes |
R4664 |
T7424 |
T7423 |
punct |
-,activated |
R4665 |
T7425 |
T7421 |
compound |
reporter,genes |
R4666 |
T7426 |
T7421 |
punct |
", ",genes |
R4667 |
T7427 |
T7421 |
appos |
HIS3,genes |
R4668 |
T7428 |
T7427 |
punct |
", ",HIS3 |
R4669 |
T7429 |
T7427 |
conj |
URA3,HIS3 |
R4670 |
T7430 |
T7429 |
cc |
and,URA3 |
R4671 |
T7431 |
T7429 |
conj |
lacZ,URA3 |
R4672 |
T7432 |
T7419 |
punct |
", ",uses |
R4673 |
T7433 |
T7434 |
aux |
to,identify |
R4674 |
T7434 |
T7419 |
advcl |
identify,uses |
R4675 |
T7435 |
T7436 |
amod |
positive,interactions |
R4676 |
T7436 |
T7434 |
dobj |
interactions,identify |
R4677 |
T7437 |
T7419 |
punct |
.,uses |
R4678 |
T7439 |
T7440 |
nsubjpass |
Reporters,activated |
R4679 |
T7441 |
T7440 |
auxpass |
are,activated |
R4680 |
T7442 |
T7443 |
advmod |
when,interacts |
R4681 |
T7443 |
T7440 |
advcl |
interacts,activated |
R4682 |
T7444 |
T7445 |
det |
the,protein |
R4683 |
T7445 |
T7443 |
nsubj |
protein,interacts |
R4684 |
T7446 |
T7445 |
compound |
bait,protein |
R4685 |
T7447 |
T7445 |
acl |
fused,protein |
R4686 |
T7448 |
T7447 |
prep |
to,fused |
R4687 |
T7449 |
T7450 |
det |
the,domain |
R4688 |
T7450 |
T7448 |
pobj |
domain,to |
R4689 |
T7451 |
T7450 |
compound |
GAL4,domain |
R4690 |
T7452 |
T7450 |
compound |
DNA,domain |
R4691 |
T7453 |
T7450 |
compound |
binding,domain |
R4692 |
T7454 |
T7450 |
punct |
(,domain |
R4693 |
T7455 |
T7450 |
appos |
pDBLeu,domain |
R4694 |
T7456 |
T7450 |
punct |
),domain |
R4695 |
T7457 |
T7443 |
prep |
with,interacts |
R4696 |
T7458 |
T7459 |
det |
the,protein |
R4697 |
T7459 |
T7457 |
pobj |
protein,with |
R4698 |
T7460 |
T7459 |
compound |
prey,protein |
R4699 |
T7461 |
T7459 |
acl |
fused,protein |
R4700 |
T7462 |
T7461 |
prep |
to,fused |
R4701 |
T7463 |
T7464 |
det |
the,domain |
R4702 |
T7464 |
T7462 |
pobj |
domain,to |
R4703 |
T7465 |
T7464 |
compound |
GAL4,domain |
R4704 |
T7466 |
T7464 |
compound |
activation,domain |
R4705 |
T7467 |
T7464 |
punct |
(,domain |
R4706 |
T7468 |
T7464 |
appos |
pPC86,domain |
R4707 |
T7469 |
T7464 |
punct |
),domain |
R4708 |
T7470 |
T7440 |
punct |
", ",activated |
R4709 |
T7471 |
T7472 |
advmod |
thus,reconstituting |
R4710 |
T7472 |
T7440 |
advcl |
reconstituting,activated |
R4711 |
T7473 |
T7474 |
compound |
GAL4,function |
R4712 |
T7474 |
T7472 |
dobj |
function,reconstituting |
R4713 |
T7475 |
T7440 |
punct |
.,activated |
R4714 |
T7477 |
T7478 |
compound |
HIS3,activation |
R4715 |
T7478 |
T7479 |
nsubj |
activation,allows |
R4716 |
T7480 |
T7479 |
dobj |
growth,allows |
R4717 |
T7481 |
T7479 |
prep |
on,allows |
R4718 |
T7482 |
T7481 |
pobj |
plates,on |
R4719 |
T7483 |
T7482 |
acl |
lacking,plates |
R4720 |
T7484 |
T7483 |
dobj |
histidine,lacking |
R4721 |
T7485 |
T7479 |
punct |
.,allows |
R4722 |
T7487 |
T7488 |
amod |
Weak,activation |
R4723 |
T7488 |
T7490 |
nsubj |
activation,suppresses |
R4724 |
T7489 |
T7488 |
compound |
URA3,activation |
R4725 |
T7491 |
T7490 |
dobj |
growth,suppresses |
R4726 |
T7492 |
T7490 |
prep |
on,suppresses |
R4727 |
T7493 |
T7492 |
pobj |
plates,on |
R4728 |
T7494 |
T7493 |
acl |
containing,plates |
R4729 |
T7495 |
T7496 |
advmod |
5,orotic |
R4730 |
T7496 |
T7500 |
amod |
orotic,acid |
R4731 |
T7497 |
T7496 |
punct |
-,orotic |
R4732 |
T7498 |
T7496 |
amod |
fluro,orotic |
R4733 |
T7499 |
T7496 |
punct |
-,orotic |
R4734 |
T7500 |
T7494 |
dobj |
acid,containing |
R4735 |
T7501 |
T7502 |
mark |
while,permits |
R4736 |
T7502 |
T7490 |
advcl |
permits,suppresses |
R4737 |
T7503 |
T7504 |
amod |
strong,activation |
R4738 |
T7504 |
T7502 |
nsubj |
activation,permits |
R4739 |
T7505 |
T7504 |
compound |
URA3,activation |
R4740 |
T7506 |
T7502 |
dobj |
growth,permits |
R4741 |
T7507 |
T7502 |
prep |
on,permits |
R4742 |
T7508 |
T7507 |
pobj |
plates,on |
R4743 |
T7509 |
T7508 |
acl |
lacking,plates |
R4744 |
T7510 |
T7509 |
dobj |
uracil,lacking |
R4745 |
T7511 |
T7490 |
punct |
.,suppresses |
R4746 |
T7513 |
T7514 |
compound |
LacZ,activation |
R4747 |
T7514 |
T7515 |
nsubj |
activation,causes |
R4748 |
T7516 |
T7517 |
compound |
X,gal |
R4749 |
T7517 |
T7519 |
nsubj |
gal,turn |
R4750 |
T7518 |
T7517 |
punct |
-,gal |
R4751 |
T7519 |
T7515 |
ccomp |
turn,causes |
R4752 |
T7520 |
T7519 |
aux |
to,turn |
R4753 |
T7521 |
T7519 |
oprd |
blue,turn |
R4754 |
T7522 |
T7521 |
prep |
in,blue |
R4755 |
T7523 |
T7524 |
det |
a,assay |
R4756 |
T7524 |
T7522 |
pobj |
assay,in |
R4757 |
T7525 |
T7526 |
compound |
beta,galactosidase |
R4758 |
T7526 |
T7524 |
compound |
galactosidase,assay |
R4759 |
T7527 |
T7526 |
punct |
-,galactosidase |
R4760 |
T7528 |
T7515 |
punct |
.,causes |
R4761 |
T7530 |
T7531 |
det |
All,assays |
R4762 |
T7531 |
T7532 |
nsubjpass |
assays,carried |
R4763 |
T7533 |
T7532 |
auxpass |
were,carried |
R4764 |
T7534 |
T7532 |
prt |
out,carried |
R4765 |
T7535 |
T7532 |
prep |
in,carried |
R4766 |
T7536 |
T7535 |
pobj |
parallel,in |
R4767 |
T7537 |
T7536 |
prep |
with,parallel |
R4768 |
T7538 |
T7539 |
det |
the,strains |
R4769 |
T7539 |
T7537 |
pobj |
strains,with |
R4770 |
T7540 |
T7539 |
nummod |
five,strains |
R4771 |
T7541 |
T7539 |
compound |
ProQuest,strains |
R4772 |
T7542 |
T7539 |
compound |
control,strains |
R4773 |
T7543 |
T7539 |
compound |
yeast,strains |
R4774 |
T7544 |
T7539 |
appos |
A,strains |
R4775 |
T7545 |
T7546 |
punct |
-,E |
R4776 |
T7546 |
T7544 |
prep |
E,A |
R4777 |
T7547 |
T7539 |
punct |
", ",strains |
R4778 |
T7548 |
T7549 |
dep |
which,range |
R4779 |
T7549 |
T7539 |
relcl |
range,strains |
R4780 |
T7550 |
T7549 |
prep |
from,range |
R4781 |
T7551 |
T7550 |
pobj |
non-interactor,from |
R4782 |
T7552 |
T7553 |
punct |
(,A |
R4783 |
T7553 |
T7551 |
parataxis |
A,non-interactor |
R4784 |
T7554 |
T7553 |
punct |
),A |
R4785 |
T7555 |
T7550 |
prep |
to,from |
R4786 |
T7556 |
T7557 |
amod |
strong,interactor |
R4787 |
T7557 |
T7555 |
pobj |
interactor,to |
R4788 |
T7558 |
T7559 |
punct |
(,E |
R4789 |
T7559 |
T7557 |
parataxis |
E,interactor |
R4790 |
T7560 |
T7559 |
punct |
),E |
R4791 |
T7561 |
T7532 |
punct |
.,carried |