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PMC:1208879 / 11404-12321 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T3389 0-2 IN denotes By
T3390 24-34 VBD denotes identified
T3391 3-10 NN denotes library
T3392 11-20 NN denotes screening
T3393 21-23 PRP denotes we
T3394 35-38 CD denotes two
T3395 39-47 NN denotes proteins
T3396 48-49 -LRB- denotes (
T3397 49-55 NN denotes HOMER3
T3398 56-59 CC denotes and
T3399 60-65 NN denotes DNCL1
T3400 65-66 -RRB- denotes )
T3401 67-71 WDT denotes that
T3402 72-80 VBP denotes interact
T3403 81-85 IN denotes with
T3404 86-89 DT denotes the
T3405 101-108 NN denotes peptide
T3406 90-91 NN denotes C
T3407 92-100 JJ denotes terminal
T3408 91-92 HYPH denotes -
T3409 109-112 CC denotes and
T3410 113-118 CD denotes three
T3411 119-127 NN denotes proteins
T3412 128-129 -LRB- denotes (
T3413 129-135 NN denotes HOMER3
T3414 135-137 , denotes ,
T3415 137-142 NN denotes DNCL1
T3416 143-146 CC denotes and
T3417 147-153 NN denotes TRIM11
T3418 153-154 -RRB- denotes )
T3419 155-159 WDT denotes that
T3420 160-168 VBP denotes interact
T3421 169-173 IN denotes with
T3422 174-177 DT denotes the
T3423 188-194 NN denotes domain
T3424 178-183 JJ denotes whole
T3425 184-187 NN denotes PST
T3426 194-195 . denotes .
T3427 195-351 sentence denotes This suggests that HOMER3 and DNCL1 interact specifically with the C-terminal peptide while TRIM11 interacts with a more N-terminal part of the PST domain.
T3428 196-200 DT denotes This
T3429 201-209 VBZ denotes suggests
T3430 210-214 IN denotes that
T3431 232-240 VBP denotes interact
T3432 215-221 NN denotes HOMER3
T3433 222-225 CC denotes and
T3434 226-231 NN denotes DNCL1
T3435 241-253 RB denotes specifically
T3436 254-258 IN denotes with
T3437 259-262 DT denotes the
T3438 274-281 NN denotes peptide
T3439 263-264 NN denotes C
T3440 265-273 JJ denotes terminal
T3441 264-265 HYPH denotes -
T3442 282-287 IN denotes while
T3443 295-304 VBZ denotes interacts
T3444 288-294 NN denotes TRIM11
T3445 305-309 IN denotes with
T3446 310-311 DT denotes a
T3447 328-332 NN denotes part
T3448 312-316 RBR denotes more
T3449 319-327 JJ denotes terminal
T3450 317-318 NN denotes N
T3451 318-319 HYPH denotes -
T3452 333-335 IN denotes of
T3453 336-339 DT denotes the
T3454 344-350 NN denotes domain
T3455 340-343 NN denotes PST
T3456 350-351 . denotes .
T3457 351-554 sentence denotes We conducted pairwise tests between specific constructs to confirm the interactions identified in the library screen and to further investigate the interaction between PAX6 and HOMER3, DNCL1 and TRIM11.
T3458 352-354 PRP denotes We
T3459 355-364 VBD denotes conducted
T3460 365-373 JJ denotes pairwise
T3461 374-379 NNS denotes tests
T3462 380-387 IN denotes between
T3463 388-396 JJ denotes specific
T3464 397-407 NNS denotes constructs
T3465 408-410 TO denotes to
T3466 411-418 VB denotes confirm
T3467 419-422 DT denotes the
T3468 423-435 NNS denotes interactions
T3469 436-446 VBN denotes identified
T3470 447-449 IN denotes in
T3471 450-453 DT denotes the
T3472 462-468 NN denotes screen
T3473 454-461 NN denotes library
T3474 469-472 CC denotes and
T3475 473-475 TO denotes to
T3476 484-495 VB denotes investigate
T3477 476-483 RB denotes further
T3478 496-499 DT denotes the
T3479 500-511 NN denotes interaction
T3480 512-519 IN denotes between
T3481 520-524 NN denotes PAX6
T3482 525-528 CC denotes and
T3483 529-535 NN denotes HOMER3
T3484 535-537 , denotes ,
T3485 537-542 NN denotes DNCL1
T3486 543-546 CC denotes and
T3487 547-553 NN denotes TRIM11
T3488 553-554 . denotes .
T3489 554-695 sentence denotes The Dncl1 and Trim11 clones that were pulled out of the library were full-length, but the Homer3 cDNAs lacked the N-terminal 70 amino acids.
T3490 555-558 DT denotes The
T3491 576-582 NNS denotes clones
T3492 559-564 NN denotes Dncl1
T3493 565-568 CC denotes and
T3494 569-575 NN denotes Trim11
T3495 619-623 VBD denotes were
T3496 583-587 WDT denotes that
T3497 593-599 VBN denotes pulled
T3498 588-592 VBD denotes were
T3499 600-603 IN denotes out
T3500 604-606 IN denotes of
T3501 607-610 DT denotes the
T3502 611-618 NN denotes library
T3503 624-628 JJ denotes full
T3504 629-635 NN denotes length
T3505 628-629 HYPH denotes -
T3506 635-637 , denotes ,
T3507 637-640 CC denotes but
T3508 641-644 DT denotes the
T3509 652-657 NNS denotes cDNAs
T3510 645-651 NN denotes Homer3
T3511 658-664 VBD denotes lacked
T3512 665-668 DT denotes the
T3513 689-694 NNS denotes acids
T3514 669-670 NN denotes N
T3515 671-679 JJ denotes terminal
T3516 670-671 HYPH denotes -
T3517 680-682 CD denotes 70
T3518 683-688 NN denotes amino
T3519 694-695 . denotes .
T3520 695-823 sentence denotes The missing coding region was inserted into the truncated Homer3 cDNA to give a full-length expression construct (see Methods).
T3521 696-699 DT denotes The
T3522 715-721 NN denotes region
T3523 700-707 JJ denotes missing
T3524 708-714 NN denotes coding
T3525 726-734 VBN denotes inserted
T3526 722-725 VBD denotes was
T3527 735-739 IN denotes into
T3528 740-743 DT denotes the
T3529 761-765 NN denotes cDNA
T3530 744-753 VBN denotes truncated
T3531 754-760 NN denotes Homer3
T3532 766-768 TO denotes to
T3533 769-773 VB denotes give
T3534 774-775 DT denotes a
T3535 799-808 NN denotes construct
T3536 776-780 JJ denotes full
T3537 781-787 NN denotes length
T3538 780-781 HYPH denotes -
T3539 788-798 NN denotes expression
T3540 809-810 -LRB- denotes (
T3541 810-813 VB denotes see
T3542 814-821 NNS denotes Methods
T3543 821-822 -RRB- denotes )
T3544 822-823 . denotes .
T3545 823-917 sentence denotes Pairwise interactions were carried out with both the full-length and truncated Homer3 clones.
T3546 824-832 JJ denotes Pairwise
T3547 833-845 NNS denotes interactions
T3548 851-858 VBN denotes carried
T3549 846-850 VBD denotes were
T3550 859-862 RP denotes out
T3551 863-867 IN denotes with
T3552 868-872 CC denotes both
T3553 910-916 NNS denotes clones
T3554 873-876 DT denotes the
T3555 877-881 JJ denotes full
T3556 882-888 NN denotes length
T3557 881-882 HYPH denotes -
T3558 889-892 CC denotes and
T3559 893-902 VBN denotes truncated
T3560 903-909 NN denotes Homer3
T3561 916-917 . denotes .
R1916 T3389 T3390 prep By,identified
R1917 T3391 T3392 compound library,screening
R1918 T3392 T3389 pobj screening,By
R1919 T3393 T3390 nsubj we,identified
R1920 T3394 T3395 nummod two,proteins
R1921 T3395 T3390 dobj proteins,identified
R1922 T3396 T3395 punct (,proteins
R1923 T3397 T3395 appos HOMER3,proteins
R1924 T3398 T3397 cc and,HOMER3
R1925 T3399 T3397 conj DNCL1,HOMER3
R1926 T3400 T3395 punct ),proteins
R1927 T3401 T3402 dep that,interact
R1928 T3402 T3395 relcl interact,proteins
R1929 T3403 T3402 prep with,interact
R1930 T3404 T3405 det the,peptide
R1931 T3405 T3403 pobj peptide,with
R1932 T3406 T3407 npadvmod C,terminal
R1933 T3407 T3405 amod terminal,peptide
R1934 T3408 T3407 punct -,terminal
R1935 T3409 T3405 cc and,peptide
R1936 T3410 T3411 nummod three,proteins
R1937 T3411 T3405 conj proteins,peptide
R1938 T3412 T3411 punct (,proteins
R1939 T3413 T3411 appos HOMER3,proteins
R1940 T3414 T3413 punct ", ",HOMER3
R1941 T3415 T3413 conj DNCL1,HOMER3
R1942 T3416 T3415 cc and,DNCL1
R1943 T3417 T3415 conj TRIM11,DNCL1
R1944 T3418 T3411 punct ),proteins
R1945 T3419 T3420 dep that,interact
R1946 T3420 T3411 relcl interact,proteins
R1947 T3421 T3420 prep with,interact
R1948 T3422 T3423 det the,domain
R1949 T3423 T3421 pobj domain,with
R1950 T3424 T3423 amod whole,domain
R1951 T3425 T3423 compound PST,domain
R1952 T3426 T3390 punct .,identified
R1953 T3428 T3429 nsubj This,suggests
R1954 T3430 T3431 mark that,interact
R1955 T3431 T3429 ccomp interact,suggests
R1956 T3432 T3431 nsubj HOMER3,interact
R1957 T3433 T3432 cc and,HOMER3
R1958 T3434 T3432 conj DNCL1,HOMER3
R1959 T3435 T3436 advmod specifically,with
R1960 T3436 T3431 prep with,interact
R1961 T3437 T3438 det the,peptide
R1962 T3438 T3436 pobj peptide,with
R1963 T3439 T3440 npadvmod C,terminal
R1964 T3440 T3438 amod terminal,peptide
R1965 T3441 T3440 punct -,terminal
R1966 T3442 T3443 mark while,interacts
R1967 T3443 T3431 advcl interacts,interact
R1968 T3444 T3443 nsubj TRIM11,interacts
R1969 T3445 T3443 prep with,interacts
R1970 T3446 T3447 det a,part
R1971 T3447 T3445 pobj part,with
R1972 T3448 T3449 advmod more,terminal
R1973 T3449 T3447 amod terminal,part
R1974 T3450 T3449 npadvmod N,terminal
R1975 T3451 T3449 punct -,terminal
R1976 T3452 T3447 prep of,part
R1977 T3453 T3454 det the,domain
R1978 T3454 T3452 pobj domain,of
R1979 T3455 T3454 compound PST,domain
R1980 T3456 T3429 punct .,suggests
R1981 T3458 T3459 nsubj We,conducted
R1982 T3460 T3461 amod pairwise,tests
R1983 T3461 T3459 dobj tests,conducted
R1984 T3462 T3461 prep between,tests
R1985 T3463 T3464 amod specific,constructs
R1986 T3464 T3462 pobj constructs,between
R1987 T3465 T3466 aux to,confirm
R1988 T3466 T3459 advcl confirm,conducted
R1989 T3467 T3468 det the,interactions
R1990 T3468 T3466 dobj interactions,confirm
R1991 T3469 T3468 acl identified,interactions
R1992 T3470 T3469 prep in,identified
R1993 T3471 T3472 det the,screen
R1994 T3472 T3470 pobj screen,in
R1995 T3473 T3472 compound library,screen
R1996 T3474 T3466 cc and,confirm
R1997 T3475 T3476 aux to,investigate
R1998 T3476 T3466 conj investigate,confirm
R1999 T3477 T3476 advmod further,investigate
R2000 T3478 T3479 det the,interaction
R2001 T3479 T3476 dobj interaction,investigate
R2002 T3480 T3479 prep between,interaction
R2003 T3481 T3480 pobj PAX6,between
R2004 T3482 T3481 cc and,PAX6
R2005 T3483 T3481 conj HOMER3,PAX6
R2006 T3484 T3481 punct ", ",PAX6
R2007 T3485 T3481 appos DNCL1,PAX6
R2008 T3486 T3485 cc and,DNCL1
R2009 T3487 T3485 conj TRIM11,DNCL1
R2010 T3488 T3459 punct .,conducted
R2011 T3490 T3491 det The,clones
R2012 T3491 T3495 nsubj clones,were
R2013 T3492 T3491 nmod Dncl1,clones
R2014 T3493 T3492 cc and,Dncl1
R2015 T3494 T3492 conj Trim11,Dncl1
R2016 T3496 T3497 dep that,pulled
R2017 T3497 T3491 relcl pulled,clones
R2018 T3498 T3497 auxpass were,pulled
R2019 T3499 T3497 prep out,pulled
R2020 T3500 T3499 prep of,out
R2021 T3501 T3502 det the,library
R2022 T3502 T3500 pobj library,of
R2023 T3503 T3504 amod full,length
R2024 T3504 T3495 attr length,were
R2025 T3505 T3504 punct -,length
R2026 T3506 T3495 punct ", ",were
R2027 T3507 T3495 cc but,were
R2028 T3508 T3509 det the,cDNAs
R2029 T3509 T3511 nsubj cDNAs,lacked
R2030 T3510 T3509 compound Homer3,cDNAs
R2031 T3511 T3495 conj lacked,were
R2032 T3512 T3513 det the,acids
R2033 T3513 T3511 dobj acids,lacked
R2034 T3514 T3515 npadvmod N,terminal
R2035 T3515 T3513 amod terminal,acids
R2036 T3516 T3515 punct -,terminal
R2037 T3517 T3513 nummod 70,acids
R2038 T3518 T3513 compound amino,acids
R2039 T3519 T3511 punct .,lacked
R2040 T3521 T3522 det The,region
R2041 T3522 T3525 nsubjpass region,inserted
R2042 T3523 T3522 amod missing,region
R2043 T3524 T3522 compound coding,region
R2044 T3526 T3525 auxpass was,inserted
R2045 T3527 T3525 prep into,inserted
R2046 T3528 T3529 det the,cDNA
R2047 T3529 T3527 pobj cDNA,into
R2048 T3530 T3529 amod truncated,cDNA
R2049 T3531 T3529 compound Homer3,cDNA
R2050 T3532 T3533 aux to,give
R2051 T3533 T3525 advcl give,inserted
R2052 T3534 T3535 det a,construct
R2053 T3535 T3533 dobj construct,give
R2054 T3536 T3537 amod full,length
R2055 T3537 T3535 compound length,construct
R2056 T3538 T3537 punct -,length
R2057 T3539 T3535 compound expression,construct
R2058 T3540 T3541 punct (,see
R2059 T3541 T3525 parataxis see,inserted
R2060 T3542 T3541 dobj Methods,see
R2061 T3543 T3541 punct ),see
R2062 T3544 T3525 punct .,inserted
R2063 T3546 T3547 amod Pairwise,interactions
R2064 T3547 T3548 nsubjpass interactions,carried
R2065 T3549 T3548 auxpass were,carried
R2066 T3550 T3548 prt out,carried
R2067 T3551 T3548 prep with,carried
R2068 T3552 T3553 preconj both,clones
R2069 T3553 T3551 pobj clones,with
R2070 T3554 T3553 det the,clones
R2071 T3555 T3556 amod full,length
R2072 T3556 T3553 nmod length,clones
R2073 T3557 T3556 punct -,length
R2074 T3558 T3556 cc and,length
R2075 T3559 T3556 conj truncated,length
R2076 T3560 T3553 compound Homer3,clones
R2077 T3561 T3548 punct .,carried

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the bag model. You can change it to the chain model.

Id Subject Object Predicate Lexical cue
T3223 39-47 CHEBI_PR_EXT:protein denotes proteins
T3224 49-55 PR_EXT:000008680 denotes HOMER3
T3225 60-65 PR_EXT:000002325 denotes DNCL1
T3226 90-100 CHEBI_SO_EXT:C_terminus_or_C_terminal_region denotes C-terminal
T3227 101-108 CHEBI_SO_EXT:peptide_or_peptide_region denotes peptide
T3228 119-127 CHEBI_PR_EXT:protein denotes proteins
T3229 129-135 PR_EXT:000008680 denotes HOMER3
T3230 137-142 PR_EXT:000002325 denotes DNCL1
T3231 147-153 PR_EXT:000016642 denotes TRIM11
T3232 188-194 SO_EXT:0000417 denotes domain
T3233 215-221 PR_EXT:000008680 denotes HOMER3
T3234 226-231 PR_EXT:000002325 denotes DNCL1
T3235 263-273 CHEBI_SO_EXT:C_terminus_or_C_terminal_region denotes C-terminal
T3236 274-281 CHEBI_SO_EXT:peptide_or_peptide_region denotes peptide
T3237 288-294 PR_EXT:000016642 denotes TRIM11
T3238 317-327 CHEBI_SO_EXT:N_terminus_or_N_terminal_region denotes N-terminal
T3239 344-350 SO_EXT:0000417 denotes domain
T3240 397-407 SO_EXT:engineered_biological_sequence denotes constructs
T3241 520-524 PR_EXT:000012318 denotes PAX6
T3242 529-535 PR_EXT:000008680 denotes HOMER3
T3243 537-542 PR_EXT:000002325 denotes DNCL1
T3244 547-553 PR_EXT:000016642 denotes TRIM11
T3245 559-564 PR_EXT:000002325 denotes Dncl1
T3246 569-575 PR_EXT:000016642 denotes Trim11
T3247 576-582 SO_EXT:sequence_cloned_entity denotes clones
T3248 645-651 PR_EXT:000008680 denotes Homer3
T3249 652-657 SO_EXT:cDNA denotes cDNAs
T3250 669-679 CHEBI_SO_EXT:N_terminus_or_N_terminal_region denotes N-terminal
T3251 683-694 CHEBI_SO_EXT:amino_acid denotes amino acids
T3252 708-721 SO_EXT:coding_sequence denotes coding region
T3253 726-734 SO_EXT:sequence_insertion_process denotes inserted
T3254 744-753 SO_EXT:sequence_truncation_process denotes truncated
T3255 754-760 PR_EXT:000008680 denotes Homer3
T3256 761-765 SO_EXT:cDNA denotes cDNA
T3257 788-798 GO:0010467 denotes expression
T3258 799-808 SO_EXT:engineered_biological_sequence denotes construct
T3259 893-902 SO_EXT:sequence_truncation_process denotes truncated
T3260 903-909 PR_EXT:000008680 denotes Homer3
T3261 910-916 SO_EXT:sequence_cloned_entity denotes clones

craft-ca-core-dev

Below, discontinuous spans are shown in the bag model. You can change it to the chain model.

Id Subject Object Predicate Lexical cue
T3138 49-55 PR:000008680 denotes HOMER3
T3139 60-65 PR:000002325 denotes DNCL1
T3140 129-135 PR:000008680 denotes HOMER3
T3141 137-142 PR:000002325 denotes DNCL1
T3142 147-153 PR:000016642 denotes TRIM11
T3143 188-194 SO:0000417 denotes domain
T3144 215-221 PR:000008680 denotes HOMER3
T3145 226-231 PR:000002325 denotes DNCL1
T3146 288-294 PR:000016642 denotes TRIM11
T3147 344-350 SO:0000417 denotes domain
T3148 520-524 PR:000012318 denotes PAX6
T3149 529-535 PR:000008680 denotes HOMER3
T3150 537-542 PR:000002325 denotes DNCL1
T3151 547-553 PR:000016642 denotes TRIM11
T3152 559-564 PR:000002325 denotes Dncl1
T3153 569-575 PR:000016642 denotes Trim11
T3154 645-651 PR:000008680 denotes Homer3
T3155 754-760 PR:000008680 denotes Homer3
T3156 788-798 GO:0010467 denotes expression
T3157 903-909 PR:000008680 denotes Homer3