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PMC:1208879 / 1140-1516 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T386 0-3 PRP$ denotes Our
T387 16-20 NNS denotes data
T388 4-15 JJ denotes preliminary
T389 21-28 VBP denotes suggest
T390 29-33 IN denotes that
T391 39-48 VBZ denotes interacts
T392 34-38 NN denotes PAX6
T393 49-53 IN denotes with
T394 54-60 NN denotes HOMER3
T395 60-62 , denotes ,
T396 62-67 NN denotes DNCL1
T397 68-71 CC denotes and
T398 72-78 NN denotes TRIM11
T399 78-79 . denotes .
T400 79-376 sentence denotes We propose that the interaction of PAX6 with HOMER3 and DNCL1 is a mechanism by which synaptic activation could lead to changes in neuronal transcriptional activity, and that some of the neural anomalies in patients with PAX6 mutations could be explained by impaired protein-protein interactions.
T401 80-82 PRP denotes We
T402 83-90 VBP denotes propose
T403 91-95 IN denotes that
T404 142-144 VBZ denotes is
T405 96-99 DT denotes the
T406 100-111 NN denotes interaction
T407 112-114 IN denotes of
T408 115-119 NN denotes PAX6
T409 120-124 IN denotes with
T410 125-131 NN denotes HOMER3
T411 132-135 CC denotes and
T412 136-141 NN denotes DNCL1
T413 145-146 DT denotes a
T414 147-156 NN denotes mechanism
T415 157-159 IN denotes by
T416 192-196 VB denotes lead
T417 160-165 WDT denotes which
T418 166-174 JJ denotes synaptic
T419 175-185 NN denotes activation
T420 186-191 MD denotes could
T421 197-199 IN denotes to
T422 200-207 NNS denotes changes
T423 208-210 IN denotes in
T424 211-219 JJ denotes neuronal
T425 236-244 NN denotes activity
T426 220-235 JJ denotes transcriptional
T427 244-246 , denotes ,
T428 246-249 CC denotes and
T429 250-254 IN denotes that
T430 325-334 VBN denotes explained
T431 255-259 DT denotes some
T432 260-262 IN denotes of
T433 263-266 DT denotes the
T434 274-283 NNS denotes anomalies
T435 267-273 JJ denotes neural
T436 284-286 IN denotes in
T437 287-295 NNS denotes patients
T438 296-300 IN denotes with
T439 301-305 NN denotes PAX6
T440 306-315 NNS denotes mutations
T441 316-321 MD denotes could
T442 322-324 VB denotes be
T443 335-337 IN denotes by
T444 338-346 JJ denotes impaired
T445 363-375 NNS denotes interactions
T446 347-354 NN denotes protein
T447 355-362 NN denotes protein
T448 354-355 SYM denotes -
T449 375-376 . denotes .
R189 T387 T389 nsubj data,suggest
R190 T388 T387 amod preliminary,data
R192 T391 T389 ccomp interacts,suggest
R193 T392 T391 nsubj PAX6,interacts
R203 T404 T402 advcl is,propose
R204 T405 T406 det the,interaction
R205 T406 T404 nsubj interaction,is
R206 T407 T406 prep of,interaction
R207 T408 T407 pobj PAX6,of
R208 T409 T406 prep with,interaction
R209 T410 T409 pobj HOMER3,with
R210 T411 T410 cc and,HOMER3
R211 T412 T410 conj DNCL1,HOMER3
R215 T416 T414 relcl lead,mechanism
R216 T417 T415 pobj which,by
R217 T418 T419 amod synaptic,activation
R218 T419 T416 nsubj activation,lead
R219 T420 T416 aux could,lead
R224 T425 T423 pobj activity,in
R225 T426 T425 amod transcriptional,activity
R229 T430 T404 conj explained,is
R230 T431 T430 nsubjpass some,explained
R231 T432 T431 prep of,some
R232 T433 T434 det the,anomalies
R234 T435 T434 amod neural,anomalies
R235 T436 T434 prep in,anomalies
R236 T437 T436 pobj patients,in
R237 T438 T437 prep with,patients
R238 T439 T440 compound PAX6,mutations
R239 T440 T438 pobj mutations,with
R240 T441 T430 aux could,explained
R241 T442 T430 auxpass be,explained
R244 T445 T443 pobj interactions,by
R245 T446 T447 nmod protein,protein
R247 T448 T447 punct -,protein
R188 T386 T387 poss Our,data
R191 T390 T391 mark that,interacts
R194 T393 T391 prep with,interacts
R195 T394 T393 pobj HOMER3,with
R196 T395 T394 punct ", ",HOMER3
R197 T396 T394 conj DNCL1,HOMER3
R198 T397 T396 cc and,DNCL1
R199 T398 T396 conj TRIM11,DNCL1
R200 T399 T389 punct .,suggest
R201 T401 T402 nsubj We,propose
R202 T403 T404 mark that,is
R212 T413 T414 det a,mechanism
R213 T414 T404 attr mechanism,is
R214 T415 T416 prep by,lead
R220 T421 T416 prep to,lead
R221 T422 T421 pobj changes,to
R222 T423 T422 prep in,changes
R223 T424 T425 amod neuronal,activity
R226 T427 T404 punct ", ",is
R227 T428 T404 cc and,is
R228 T429 T430 mark that,explained
R233 T434 T432 pobj anomalies,of
R242 T443 T430 prep by,explained
R243 T444 T445 amod impaired,interactions
R246 T447 T445 compound protein,interactions
R248 T449 T402 punct .,propose

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T161 34-38 PR_EXT:000012318 denotes PAX6
T162 54-60 PR_EXT:000008680 denotes HOMER3
T163 62-67 PR_EXT:000002325 denotes DNCL1
T164 72-78 PR_EXT:000016642 denotes TRIM11
T165 115-119 PR_EXT:000012318 denotes PAX6
T166 125-131 PR_EXT:000008680 denotes HOMER3
T167 136-141 PR_EXT:000002325 denotes DNCL1
T168 166-174 GO:0045202 denotes synaptic
T169 211-219 CL:0000540 denotes neuronal
T170 220-235 GO_EXT:transcription denotes transcriptional
T171 267-273 UBERON_EXT:neural_tissue_or_nerve_or_nervous_system denotes neural
T172 301-305 PR_EXT:000012318 denotes PAX6
T173 306-315 SO_EXT:sequence_alteration_entity_or_process denotes mutations
T174 347-354 CHEBI_PR_EXT:protein denotes protein
T103 355-362 CHEBI_PR_EXT:protein denotes protein

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T93 34-38 PR:000012318 denotes PAX6
T94 54-60 PR:000008680 denotes HOMER3
T95 62-67 PR:000002325 denotes DNCL1
T96 72-78 PR:000016642 denotes TRIM11
T97 115-119 PR:000012318 denotes PAX6
T98 125-131 PR:000008680 denotes HOMER3
T99 136-141 PR:000002325 denotes DNCL1
T100 166-174 GO:0045202 denotes synaptic
T101 211-219 CL:0000540 denotes neuronal
T102 301-305 PR:000012318 denotes PAX6