Id |
Subject |
Object |
Predicate |
Lexical cue |
T7725 |
0-4 |
NNS |
denotes |
Mice |
T7726 |
5-8 |
CC |
denotes |
and |
T7727 |
9-19 |
NN |
denotes |
genotyping |
T7728 |
19-167 |
sentence |
denotes |
The Hdhex4/5 mice carrying a pGKneo insertion/replacement inactivating mutation in the mouse HD gene homologue have been described previously [10]. |
T7729 |
20-23 |
DT |
denotes |
The |
T7730 |
33-37 |
NNS |
denotes |
mice |
T7731 |
24-30 |
NN |
denotes |
Hdhex4 |
T7732 |
30-31 |
HYPH |
denotes |
/ |
T7733 |
31-32 |
CD |
denotes |
5 |
T7734 |
141-150 |
VBN |
denotes |
described |
T7735 |
38-46 |
VBG |
denotes |
carrying |
T7736 |
47-48 |
DT |
denotes |
a |
T7737 |
91-99 |
NN |
denotes |
mutation |
T7738 |
49-55 |
NN |
denotes |
pGKneo |
T7739 |
66-77 |
NN |
denotes |
replacement |
T7740 |
56-65 |
NN |
denotes |
insertion |
T7741 |
65-66 |
HYPH |
denotes |
/ |
T7742 |
78-90 |
VBG |
denotes |
inactivating |
T7743 |
100-102 |
IN |
denotes |
in |
T7744 |
103-106 |
DT |
denotes |
the |
T7745 |
121-130 |
NN |
denotes |
homologue |
T7746 |
107-112 |
NN |
denotes |
mouse |
T7747 |
113-115 |
NN |
denotes |
HD |
T7748 |
116-120 |
NN |
denotes |
gene |
T7749 |
131-135 |
VBP |
denotes |
have |
T7750 |
136-140 |
VBN |
denotes |
been |
T7751 |
151-161 |
RB |
denotes |
previously |
T7752 |
162-163 |
-LRB- |
denotes |
[ |
T7753 |
163-165 |
CD |
denotes |
10 |
T7754 |
165-166 |
-RRB- |
denotes |
] |
T7755 |
166-167 |
. |
denotes |
. |
T7756 |
167-294 |
sentence |
denotes |
The experiments were conducted in accordance with an IACUC approved protocol, through the MGH Subcommittee on Animal Research. |
T7757 |
168-171 |
DT |
denotes |
The |
T7758 |
172-183 |
NNS |
denotes |
experiments |
T7759 |
189-198 |
VBN |
denotes |
conducted |
T7760 |
184-188 |
VBD |
denotes |
were |
T7761 |
199-201 |
IN |
denotes |
in |
T7762 |
202-212 |
NN |
denotes |
accordance |
T7763 |
213-217 |
IN |
denotes |
with |
T7764 |
218-220 |
DT |
denotes |
an |
T7765 |
236-244 |
NN |
denotes |
protocol |
T7766 |
221-226 |
NNP |
denotes |
IACUC |
T7767 |
227-235 |
VBN |
denotes |
approved |
T7768 |
244-246 |
, |
denotes |
, |
T7769 |
246-253 |
IN |
denotes |
through |
T7770 |
254-257 |
DT |
denotes |
the |
T7771 |
262-274 |
NNP |
denotes |
Subcommittee |
T7772 |
258-261 |
NNP |
denotes |
MGH |
T7773 |
275-277 |
IN |
denotes |
on |
T7774 |
278-284 |
NNP |
denotes |
Animal |
T7775 |
285-293 |
NNP |
denotes |
Research |
T7776 |
293-294 |
. |
denotes |
. |
T7777 |
294-464 |
sentence |
denotes |
Mutant Hdhex4/5/Hdhex4/5 and normal littermates were obtained in timed pregnancies from mating of Hdhex4/5/Hdh+ heterozygotes, genotyped by PCR assay, as described [10]. |
T7778 |
295-301 |
NN |
denotes |
Mutant |
T7779 |
302-308 |
NN |
denotes |
Hdhex4 |
T7780 |
331-342 |
NNS |
denotes |
littermates |
T7781 |
308-309 |
HYPH |
denotes |
/ |
T7782 |
309-310 |
CD |
denotes |
5 |
T7783 |
310-311 |
HYPH |
denotes |
/ |
T7784 |
311-317 |
NN |
denotes |
Hdhex4 |
T7785 |
317-318 |
HYPH |
denotes |
/ |
T7786 |
318-319 |
CD |
denotes |
5 |
T7787 |
320-323 |
CC |
denotes |
and |
T7788 |
324-330 |
JJ |
denotes |
normal |
T7789 |
348-356 |
VBN |
denotes |
obtained |
T7790 |
343-347 |
VBD |
denotes |
were |
T7791 |
357-359 |
IN |
denotes |
in |
T7792 |
360-365 |
VBN |
denotes |
timed |
T7793 |
366-377 |
NNS |
denotes |
pregnancies |
T7794 |
378-382 |
IN |
denotes |
from |
T7795 |
383-389 |
NN |
denotes |
mating |
T7796 |
390-392 |
IN |
denotes |
of |
T7797 |
393-399 |
NN |
denotes |
Hdhex4 |
T7798 |
407-420 |
NNS |
denotes |
heterozygotes |
T7799 |
399-400 |
HYPH |
denotes |
/ |
T7800 |
400-401 |
CD |
denotes |
5 |
T7801 |
401-402 |
HYPH |
denotes |
/ |
T7802 |
402-405 |
NN |
denotes |
Hdh |
T7803 |
405-406 |
SYM |
denotes |
+ |
T7804 |
420-422 |
, |
denotes |
, |
T7805 |
422-431 |
VBN |
denotes |
genotyped |
T7806 |
432-434 |
IN |
denotes |
by |
T7807 |
435-438 |
NN |
denotes |
PCR |
T7808 |
439-444 |
NN |
denotes |
assay |
T7809 |
444-446 |
, |
denotes |
, |
T7810 |
446-448 |
IN |
denotes |
as |
T7811 |
449-458 |
VBN |
denotes |
described |
T7812 |
459-460 |
-LRB- |
denotes |
[ |
T7813 |
460-462 |
CD |
denotes |
10 |
T7814 |
462-463 |
-RRB- |
denotes |
] |
T7815 |
463-464 |
. |
denotes |
. |
T7816 |
464-502 |
sentence |
denotes |
The day of plug was taken to be E0.5. |
T7817 |
465-468 |
DT |
denotes |
The |
T7818 |
469-472 |
NN |
denotes |
day |
T7819 |
485-490 |
VBN |
denotes |
taken |
T7820 |
473-475 |
IN |
denotes |
of |
T7821 |
476-480 |
NN |
denotes |
plug |
T7822 |
481-484 |
VBD |
denotes |
was |
T7823 |
491-493 |
TO |
denotes |
to |
T7824 |
494-496 |
VB |
denotes |
be |
T7825 |
497-501 |
NN |
denotes |
E0.5 |
T7826 |
501-502 |
. |
denotes |
. |
T7827 |
502-616 |
sentence |
denotes |
Embryos that were morphologically normal were pooled separately from morphologically mutant embryos for analysis. |
T7828 |
503-510 |
NNS |
denotes |
Embryos |
T7829 |
549-555 |
VBN |
denotes |
pooled |
T7830 |
511-515 |
WDT |
denotes |
that |
T7831 |
516-520 |
VBD |
denotes |
were |
T7832 |
521-536 |
RB |
denotes |
morphologically |
T7833 |
537-543 |
JJ |
denotes |
normal |
T7834 |
544-548 |
VBD |
denotes |
were |
T7835 |
556-566 |
RB |
denotes |
separately |
T7836 |
567-571 |
IN |
denotes |
from |
T7837 |
572-587 |
RB |
denotes |
morphologically |
T7838 |
588-594 |
NN |
denotes |
mutant |
T7839 |
595-602 |
NNS |
denotes |
embryos |
T7840 |
603-606 |
IN |
denotes |
for |
T7841 |
607-615 |
NN |
denotes |
analysis |
T7842 |
615-616 |
. |
denotes |
. |
T7843 |
616-771 |
sentence |
denotes |
Nodal expression was determined in embryos from matings of Hdhex4/5/Hdh+; NdllacZ/Ndl+ compound heterozygotes genotyped by PCR assay as described in [29]. |
T7844 |
617-622 |
NN |
denotes |
Nodal |
T7845 |
623-633 |
NN |
denotes |
expression |
T7846 |
638-648 |
VBN |
denotes |
determined |
T7847 |
634-637 |
VBD |
denotes |
was |
T7848 |
649-651 |
IN |
denotes |
in |
T7849 |
652-659 |
NNS |
denotes |
embryos |
T7850 |
660-664 |
IN |
denotes |
from |
T7851 |
665-672 |
NNS |
denotes |
matings |
T7852 |
673-675 |
IN |
denotes |
of |
T7853 |
676-682 |
NN |
denotes |
Hdhex4 |
T7854 |
713-726 |
NNS |
denotes |
heterozygotes |
T7855 |
682-683 |
HYPH |
denotes |
/ |
T7856 |
683-684 |
CD |
denotes |
5 |
T7857 |
684-685 |
HYPH |
denotes |
/ |
T7858 |
685-688 |
NN |
denotes |
Hdh |
T7859 |
688-689 |
SYM |
denotes |
+ |
T7860 |
689-690 |
, |
denotes |
; |
T7861 |
691-698 |
NN |
denotes |
NdllacZ |
T7862 |
699-702 |
NN |
denotes |
Ndl |
T7863 |
698-699 |
HYPH |
denotes |
/ |
T7864 |
702-703 |
SYM |
denotes |
+ |
T7865 |
704-712 |
NN |
denotes |
compound |
T7866 |
727-736 |
VBN |
denotes |
genotyped |
T7867 |
737-739 |
IN |
denotes |
by |
T7868 |
740-743 |
NN |
denotes |
PCR |
T7869 |
744-749 |
NN |
denotes |
assay |
T7870 |
750-752 |
IN |
denotes |
as |
T7871 |
753-762 |
VBN |
denotes |
described |
T7872 |
763-765 |
IN |
denotes |
in |
T7873 |
766-767 |
-LRB- |
denotes |
[ |
T7874 |
767-769 |
CD |
denotes |
29 |
T7875 |
769-770 |
-RRB- |
denotes |
] |
T7876 |
770-771 |
. |
denotes |
. |
R4667 |
T7726 |
T7725 |
cc |
and,Mice |
R4668 |
T7727 |
T7725 |
conj |
genotyping,Mice |
R4669 |
T7729 |
T7730 |
det |
The,mice |
R4670 |
T7730 |
T7734 |
nsubjpass |
mice,described |
R4671 |
T7731 |
T7730 |
nmod |
Hdhex4,mice |
R4672 |
T7732 |
T7731 |
punct |
/,Hdhex4 |
R4673 |
T7733 |
T7731 |
nummod |
5,Hdhex4 |
R4674 |
T7735 |
T7730 |
acl |
carrying,mice |
R4675 |
T7736 |
T7737 |
det |
a,mutation |
R4676 |
T7737 |
T7735 |
dobj |
mutation,carrying |
R4677 |
T7738 |
T7739 |
compound |
pGKneo,replacement |
R4678 |
T7739 |
T7742 |
npadvmod |
replacement,inactivating |
R4679 |
T7740 |
T7739 |
compound |
insertion,replacement |
R4680 |
T7741 |
T7739 |
punct |
/,replacement |
R4681 |
T7742 |
T7737 |
amod |
inactivating,mutation |
R4682 |
T7743 |
T7735 |
prep |
in,carrying |
R4683 |
T7744 |
T7745 |
det |
the,homologue |
R4684 |
T7745 |
T7743 |
pobj |
homologue,in |
R4685 |
T7746 |
T7745 |
compound |
mouse,homologue |
R4686 |
T7747 |
T7745 |
compound |
HD,homologue |
R4687 |
T7748 |
T7745 |
compound |
gene,homologue |
R4688 |
T7749 |
T7734 |
aux |
have,described |
R4689 |
T7750 |
T7734 |
auxpass |
been,described |
R4690 |
T7751 |
T7734 |
advmod |
previously,described |
R4691 |
T7752 |
T7753 |
punct |
[,10 |
R4692 |
T7753 |
T7734 |
parataxis |
10,described |
R4693 |
T7754 |
T7753 |
punct |
],10 |
R4694 |
T7755 |
T7734 |
punct |
.,described |
R4695 |
T7757 |
T7758 |
det |
The,experiments |
R4696 |
T7758 |
T7759 |
nsubjpass |
experiments,conducted |
R4697 |
T7760 |
T7759 |
auxpass |
were,conducted |
R4698 |
T7761 |
T7759 |
prep |
in,conducted |
R4699 |
T7762 |
T7761 |
pobj |
accordance,in |
R4700 |
T7763 |
T7762 |
prep |
with,accordance |
R4701 |
T7764 |
T7765 |
det |
an,protocol |
R4702 |
T7765 |
T7763 |
pobj |
protocol,with |
R4703 |
T7766 |
T7767 |
npadvmod |
IACUC,approved |
R4704 |
T7767 |
T7765 |
amod |
approved,protocol |
R4705 |
T7768 |
T7759 |
punct |
", ",conducted |
R4706 |
T7769 |
T7759 |
prep |
through,conducted |
R4707 |
T7770 |
T7771 |
det |
the,Subcommittee |
R4708 |
T7771 |
T7769 |
pobj |
Subcommittee,through |
R4709 |
T7772 |
T7771 |
compound |
MGH,Subcommittee |
R4710 |
T7773 |
T7771 |
prep |
on,Subcommittee |
R4711 |
T7774 |
T7775 |
compound |
Animal,Research |
R4712 |
T7775 |
T7773 |
pobj |
Research,on |
R4713 |
T7776 |
T7759 |
punct |
.,conducted |
R4714 |
T7778 |
T7779 |
nmod |
Mutant,Hdhex4 |
R4715 |
T7779 |
T7780 |
nmod |
Hdhex4,littermates |
R4716 |
T7780 |
T7789 |
nsubjpass |
littermates,obtained |
R4717 |
T7781 |
T7779 |
punct |
/,Hdhex4 |
R4718 |
T7782 |
T7779 |
nummod |
5,Hdhex4 |
R4719 |
T7783 |
T7779 |
punct |
/,Hdhex4 |
R4720 |
T7784 |
T7779 |
appos |
Hdhex4,Hdhex4 |
R4721 |
T7785 |
T7784 |
punct |
/,Hdhex4 |
R4722 |
T7786 |
T7784 |
nummod |
5,Hdhex4 |
R4723 |
T7787 |
T7779 |
cc |
and,Hdhex4 |
R4724 |
T7788 |
T7779 |
conj |
normal,Hdhex4 |
R4725 |
T7790 |
T7789 |
auxpass |
were,obtained |
R4726 |
T7791 |
T7789 |
prep |
in,obtained |
R4727 |
T7792 |
T7793 |
amod |
timed,pregnancies |
R4728 |
T7793 |
T7791 |
pobj |
pregnancies,in |
R4729 |
T7794 |
T7789 |
prep |
from,obtained |
R4730 |
T7795 |
T7794 |
pobj |
mating,from |
R4731 |
T7796 |
T7795 |
prep |
of,mating |
R4732 |
T7797 |
T7798 |
nmod |
Hdhex4,heterozygotes |
R4733 |
T7798 |
T7796 |
pobj |
heterozygotes,of |
R4734 |
T7799 |
T7797 |
punct |
/,Hdhex4 |
R4735 |
T7800 |
T7797 |
nummod |
5,Hdhex4 |
R4736 |
T7801 |
T7797 |
punct |
/,Hdhex4 |
R4737 |
T7802 |
T7797 |
appos |
Hdh,Hdhex4 |
R4738 |
T7803 |
T7802 |
punct |
+,Hdh |
R4739 |
T7804 |
T7798 |
punct |
", ",heterozygotes |
R4740 |
T7805 |
T7798 |
acl |
genotyped,heterozygotes |
R4741 |
T7806 |
T7805 |
prep |
by,genotyped |
R4742 |
T7807 |
T7808 |
compound |
PCR,assay |
R4743 |
T7808 |
T7806 |
pobj |
assay,by |
R4744 |
T7809 |
T7789 |
punct |
", ",obtained |
R4745 |
T7810 |
T7811 |
mark |
as,described |
R4746 |
T7811 |
T7789 |
advcl |
described,obtained |
R4747 |
T7812 |
T7813 |
punct |
[,10 |
R4748 |
T7813 |
T7811 |
parataxis |
10,described |
R4749 |
T7814 |
T7813 |
punct |
],10 |
R4750 |
T7815 |
T7789 |
punct |
.,obtained |
R4751 |
T7817 |
T7818 |
det |
The,day |
R4752 |
T7818 |
T7819 |
nsubjpass |
day,taken |
R4753 |
T7820 |
T7818 |
prep |
of,day |
R4754 |
T7821 |
T7820 |
pobj |
plug,of |
R4755 |
T7822 |
T7819 |
auxpass |
was,taken |
R4756 |
T7823 |
T7824 |
aux |
to,be |
R4757 |
T7824 |
T7819 |
xcomp |
be,taken |
R4758 |
T7825 |
T7824 |
attr |
E0.5,be |
R4759 |
T7826 |
T7819 |
punct |
.,taken |
R4760 |
T7828 |
T7829 |
nsubjpass |
Embryos,pooled |
R4761 |
T7830 |
T7831 |
dep |
that,were |
R4762 |
T7831 |
T7828 |
relcl |
were,Embryos |
R4763 |
T7832 |
T7833 |
advmod |
morphologically,normal |
R4764 |
T7833 |
T7831 |
acomp |
normal,were |
R4765 |
T7834 |
T7829 |
auxpass |
were,pooled |
R4766 |
T7835 |
T7836 |
advmod |
separately,from |
R4767 |
T7836 |
T7829 |
prep |
from,pooled |
R4768 |
T7837 |
T7838 |
advmod |
morphologically,mutant |
R4769 |
T7838 |
T7839 |
compound |
mutant,embryos |
R4770 |
T7839 |
T7836 |
pobj |
embryos,from |
R4771 |
T7840 |
T7829 |
prep |
for,pooled |
R4772 |
T7841 |
T7840 |
pobj |
analysis,for |
R4773 |
T7842 |
T7829 |
punct |
.,pooled |
R4774 |
T7844 |
T7845 |
compound |
Nodal,expression |
R4775 |
T7845 |
T7846 |
nsubjpass |
expression,determined |
R4776 |
T7847 |
T7846 |
auxpass |
was,determined |
R4777 |
T7848 |
T7846 |
prep |
in,determined |
R4778 |
T7849 |
T7848 |
pobj |
embryos,in |
R4779 |
T7850 |
T7849 |
prep |
from,embryos |
R4780 |
T7851 |
T7850 |
pobj |
matings,from |
R4781 |
T7852 |
T7851 |
prep |
of,matings |
R4782 |
T7853 |
T7854 |
nmod |
Hdhex4,heterozygotes |
R4783 |
T7854 |
T7852 |
pobj |
heterozygotes,of |
R4784 |
T7855 |
T7853 |
punct |
/,Hdhex4 |
R4785 |
T7856 |
T7853 |
nummod |
5,Hdhex4 |
R4786 |
T7857 |
T7853 |
punct |
/,Hdhex4 |
R4787 |
T7858 |
T7853 |
appos |
Hdh,Hdhex4 |
R4788 |
T7859 |
T7858 |
punct |
+,Hdh |
R4789 |
T7860 |
T7853 |
punct |
;,Hdhex4 |
R4790 |
T7861 |
T7862 |
compound |
NdllacZ,Ndl |
R4791 |
T7862 |
T7853 |
appos |
Ndl,Hdhex4 |
R4792 |
T7863 |
T7862 |
punct |
/,Ndl |
R4793 |
T7864 |
T7862 |
punct |
+,Ndl |
R4794 |
T7865 |
T7854 |
compound |
compound,heterozygotes |
R4795 |
T7866 |
T7854 |
acl |
genotyped,heterozygotes |
R4796 |
T7867 |
T7866 |
prep |
by,genotyped |
R4797 |
T7868 |
T7869 |
compound |
PCR,assay |
R4798 |
T7869 |
T7867 |
pobj |
assay,by |
R4799 |
T7870 |
T7871 |
mark |
as,described |
R4800 |
T7871 |
T7866 |
advcl |
described,genotyped |
R4801 |
T7872 |
T7871 |
prep |
in,described |
R4802 |
T7873 |
T7874 |
punct |
[,29 |
R4803 |
T7874 |
T7872 |
pobj |
29,in |
R4804 |
T7875 |
T7874 |
punct |
],29 |
R4805 |
T7876 |
T7846 |
punct |
.,determined |