PMC:1186732 / 48728-49111 JSONTXT

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    craft-sa-dev

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contrast to the ERG differences between mouse rd7 and human NR2E3 mutants, both species demonstrate slow retinal degeneration. It is possible that this degeneration is attributable to the abnormal function of the hybrid photoreceptor cell type characterized in the present study. The coexpression of both rod and cone genes in the same cell could predispose the cell to apoptosis."}

    craft-ca-core-ex-dev

    {"project":"craft-ca-core-ex-dev","denotations":[{"id":"T8313","span":{"begin":43,"end":48},"obj":"NCBITaxon:10088"},{"id":"T8314","span":{"begin":57,"end":62},"obj":"NCBITaxon:9606"},{"id":"T8315","span":{"begin":63,"end":68},"obj":"PR_EXT:000011403"},{"id":"T8316","span":{"begin":69,"end":76},"obj":"SO_EXT:sequence_altered_entity"},{"id":"T8317","span":{"begin":83,"end":90},"obj":"NCBITaxon:species"},{"id":"T8318","span":{"begin":108,"end":115},"obj":"UBERON:0000966"},{"id":"T8319","span":{"begin":223,"end":241},"obj":"CL:0000210"},{"id":"T8320","span":{"begin":237,"end":241},"obj":"CL_GO_EXT:cell"},{"id":"T8321","span":{"begin":289,"end":299},"obj":"GO:0010467"},{"id":"T8322","span":{"begin":308,"end":311},"obj":"CL:0000604"},{"id":"T8323","span":{"begin":316,"end":320},"obj":"CL:0000573"},{"id":"T8324","span":{"begin":321,"end":326},"obj":"SO_EXT:0000704"},{"id":"T8325","span":{"begin":339,"end":343},"obj":"CL_GO_EXT:cell"},{"id":"T8326","span":{"begin":365,"end":369},"obj":"CL_GO_EXT:cell"},{"id":"T8327","span":{"begin":373,"end":382},"obj":"GO:0006915"}],"text":"In contrast to the ERG differences between mouse rd7 and human NR2E3 mutants, both species demonstrate slow retinal degeneration. It is possible that this degeneration is attributable to the abnormal function of the hybrid photoreceptor cell type characterized in the present study. The coexpression of both rod and cone genes in the same cell could predispose the cell to apoptosis."}

    craft-ca-core-dev

    {"project":"craft-ca-core-dev","denotations":[{"id":"T7743","span":{"begin":43,"end":48},"obj":"NCBITaxon:10088"},{"id":"T7744","span":{"begin":57,"end":62},"obj":"NCBITaxon:9606"},{"id":"T7745","span":{"begin":63,"end":68},"obj":"PR:000011403"},{"id":"T7746","span":{"begin":83,"end":90},"obj":"NCBITaxon:species"},{"id":"T7747","span":{"begin":108,"end":115},"obj":"UBERON:0000966"},{"id":"T7748","span":{"begin":223,"end":241},"obj":"CL:0000210"},{"id":"T7749","span":{"begin":289,"end":299},"obj":"GO:0010467"},{"id":"T7750","span":{"begin":308,"end":311},"obj":"CL:0000604"},{"id":"T7751","span":{"begin":316,"end":320},"obj":"CL:0000573"},{"id":"T7752","span":{"begin":321,"end":326},"obj":"SO:0000704"},{"id":"T7753","span":{"begin":373,"end":382},"obj":"GO:0006915"}],"text":"In contrast to the ERG differences between mouse rd7 and human NR2E3 mutants, both species demonstrate slow retinal degeneration. It is possible that this degeneration is attributable to the abnormal function of the hybrid photoreceptor cell type characterized in the present study. The coexpression of both rod and cone genes in the same cell could predispose the cell to apoptosis."}